CN114813299A - Medicine sensitive detection sample sampling pretreatment mixing arrangement - Google Patents
Medicine sensitive detection sample sampling pretreatment mixing arrangement Download PDFInfo
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- CN114813299A CN114813299A CN202210505903.XA CN202210505903A CN114813299A CN 114813299 A CN114813299 A CN 114813299A CN 202210505903 A CN202210505903 A CN 202210505903A CN 114813299 A CN114813299 A CN 114813299A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
- G01N2001/386—Other diluting or mixing processes
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Abstract
A sampling pretreatment mixing device for drug sensitive detection samples comprises a supporting plate, wherein one side of the supporting plate is fixedly connected with a containing shell and a workbench, the workbench is arranged below the containing shell, an assembly hole is formed in the upper end of the containing shell, a mixing shaft is rotationally arranged in the assembly hole, threads are arranged in a hole in the mixing shaft, a threaded rod is arranged in the mixing shaft, a mixing component is fixedly arranged on the outer side of the mixing shaft, an auxiliary component is arranged at the end part of the mixing component, one side of the containing shell is fixedly arranged on the supporting plate, a drug receiving port is fixedly arranged on the other side of the containing shell, a square through hole is formed in the drug receiving port, the containing shell continuously moves when reaching the position of a smearing rotating shaft, the rotating direction of the smearing rotating shaft is opposite to the moving direction of a detection flat plate, and the process not only greatly smears bacterial colonies to be detected on the detection flat plate uniformly, the test result is more accurate, the time for coating the bacterial colony is greatly shortened, and the efficiency is improved.
Description
Technical Field
The invention relates to the technical field of drug sensitivity detection, in particular to a sampling, preprocessing and mixing device for a drug sensitivity detection sample.
Background
With the continuous emergence of new pathogenic bacteria, the prevention and treatment effect of the antibacterial drugs is increasingly poor. And the sensitivity of various pathogenic bacteria to different antibacterial drugs is different, and the sensitivity of different strains of the same bacterium to different antibacterial drugs is also different. For a long time, the generation of drug resistance of various pathogenic bacteria causes various common antibacterial drugs to lose the efficacy and can not well master the sensitivity of the drugs to the bacteria, so that drug sensitivity tests are needed.
At present, the most widely used method for drug sensitivity test is plate method, i.e. a filter paper sheet containing quantitative antibacterial drugs is stuck on the surface of agar inoculated with test bacteria, the drugs in the paper sheet are diffused in the agar, and the concentration of the antibacterial drugs is logarithmically reduced along with the increase of diffusion distance, so that a concentration gradient is formed around the paper sheet. Meanwhile, the bacterial strains in the bacteriostatic concentration range around the paper sheet can not grow, and the bacterial strains outside the bacteriostatic range can grow, so that transparent bacteriostatic rings are formed around the paper sheet, the diameters of the bacteriostatic rings of different bacteriostatic drugs can be different due to the influence of the diffusion speed of the drugs in the agar, and the size of the bacteriostatic ring can reflect the sensitivity of the test bacteria to the drugs. But the operation steps are complicated and fragmentary, and the use efficiency is greatly reduced.
In order to solve the problems, the invention provides a sampling, preprocessing and mixing device for a drug sensitive detection sample.
Disclosure of Invention
(1) Technical problem to be solved
The invention aims to overcome the problems in the prior art, adapt to practical needs and provide a sampling pretreatment mixing device for a drug sensitive detection sample so as to solve the technical problems.
(2) Technical scheme
In order to realize the purpose of the invention, the technical scheme adopted by the invention is as follows: a sampling pretreatment mixing device for drug sensitive detection samples comprises a supporting plate, wherein one side of the supporting plate is fixedly connected with a containing shell and a workbench, the workbench is arranged below the containing shell, an assembly hole is formed in the upper end of the containing shell, a mixing shaft is rotationally arranged in the assembly hole, threads are arranged in a hole in the mixing shaft, a threaded rod is arranged in the mixing shaft, a mixing component is fixedly arranged on the outer side of the mixing shaft, an auxiliary component is arranged at the end part of the mixing component, one side of the containing shell is fixedly arranged on the supporting plate, the other side of the containing shell is fixedly provided with a drug receiving port, a square through hole is formed in the drug receiving port and is communicated with the inside of the containing shell, an outflow port is fixedly arranged below the containing shell, a smearing component is arranged below the outflow port, and fixed components are arranged at the two end parts of the smearing component, the workbench is provided with a first guide groove and a second guide groove, the second guide groove is arranged at one side of the first guide groove, the first guide groove is communicated with the second guide groove, a T-shaped sliding block is arranged in the first guide groove in a sliding way, a support table is fixedly connected on the T-shaped slide block, one end of the support table is provided with a first containing groove, the other end is provided with a detection flat plate, the two sides of the detection flat plate are provided with clamping blocks, one side of each clamping block is fixedly provided with a first spring, the end part of the first spring is fixedly provided with a supporting block which is fixedly arranged on the upper surface of the supporting table, a transmission rod is arranged in the second guide groove, the coating assembly is arranged on the transmission rod, the rotating wheel is arranged on one side of the lower portion of the transmission rod and is rotatably arranged in the second guide groove, one side of the rotating wheel is in close contact with the T-shaped sliding block, and the other side of the rotating wheel is in close contact with the transmission rod.
Preferentially, the mixing assembly comprises a first mixing partition plate and a second mixing partition plate, the first mixing partition plate is fixedly arranged on the outer side of the mixing shaft, the second mixing partition plate is arranged on one side of the first mixing partition plate, a mixing tank is arranged on the first mixing partition plate and extends downwards to the bottom of the first mixing partition plate, a second accommodating groove is formed in the end part of the second mixing partition plate, and the second accommodating groove penetrates through the upper surface and the lower surface of the second mixing partition plate.
Preferably, the auxiliary assembly includes a third guide groove, the third guide groove is opened at one side of the first mixing partition plate, a second spring is fixedly arranged in the third guide groove, and a second mixing partition plate is fixedly arranged at one side of the second spring.
Preferentially, paint the subassembly including paint the pivot, should paint pivot one end and rotate and set up in one side of backup pad, the other end sets up on the transfer line, it is provided with the cotton to paint the winding in the pivot, this cotton and egress opening lower surface in close contact with.
Preferentially, fixed subassembly includes the assembly groove, and this assembly groove is seted up and is paintd in the pivot, and this assembly groove internal fixation is provided with the back shaft, is provided with arc clamp splice and torsional spring on this back shaft, be provided with the torsional spring in the arc clamp splice, arc clamp splice clamping face is the arc.
Preferentially, the lower surface of egress opening is the arc, the equal circular arc transition in backup pad corner department, the fixed landing leg that is provided with of lower surface of workstation.
(3) Has the advantages that:
A. the threaded rod is pulled, under the action of thread transmission, the mixing shaft and the first mixing partition plate and the second mixing partition plate fixedly connected with the mixing shaft can rotate, physiological saline in the accommodating shell is stirred, and bacterial colonies at the end part of the inoculating loop can be promoted to be fused into the saline in the process;
B. a second spring is arranged in a third guide groove formed in the first mixing partition plate, and can apply certain thrust to the second mixing partition plate to enable the second mixing partition plate to be always attached to the inner wall of the accommodating shell, and impurities remained on the inner wall of the accommodating shell after a test can be cleaned while the second mixing partition plate rotates;
C. the bacterial colonies mixed by stirring can flow downwards through the outflow opening, the cotton cloth is soaked at the position where the cotton cloth is arranged at the bottom of the outflow opening, the T-shaped sliding block and the supporting table fixedly arranged on the T-shaped sliding block are pushed along the first guide groove, meanwhile, the T-shaped sliding block drives the rotating wheel to rotate, the rotating wheel drives the transmission rod to move, but the transmission rod and the T-shaped sliding block are opposite in moving direction, the transmission rod drives the smearing rotating shaft to rotate clockwise, the bacterial colonies to be tested can be smeared on the detection flat plate uniformly along with the movement of the detection flat plate along the first guide groove and continue to move when reaching the smearing rotating shaft, and the rotating direction of the smearing rotating shaft is opposite to the moving direction of the detection flat plate at the moment;
D. this fixed subassembly sets up in paining the pivot, can carry out the centre gripping to the winding at paining the epaxial cotton of commentaries on classics under the torsional spring effect, makes the cotton can realize paining the action, and arc clamp splice clamping face adopts the arc, and the pivot is paintd in laminating that can be better, and it is more firm to let the centre gripping, when needing to be changed the cotton, only need break off with the fingers and thumb the arc clamp splice can, change convenient and fast, be favorable to the health.
Drawings
FIG. 1 is a schematic perspective view of a mixing device for sampling and pretreating a drug sensitive test sample according to the present invention;
FIG. 2 is a schematic perspective view of another embodiment of a mixing device for sampling and pre-treating drug sensitive samples according to the present invention;
FIG. 3 is a schematic structural view of a mixing device for sampling and pretreating a drug sensitive test sample according to the present invention;
FIG. 4 is a schematic view of the structure of the transmission rod of the mixing device for sampling and pretreating drug sensitive test samples according to the present invention;
FIG. 5 is a schematic view of the structure of the threaded rod of the sampling and pre-processing mixing device for drug sensitive detection samples according to the present invention;
FIG. 6 is a schematic view of another angle of the threaded rod of the mixing device for sampling and pre-treating drug sensitive samples according to the present invention;
FIG. 7 is a schematic structural diagram of an auxiliary component of a sampling and pre-processing mixing device for drug sensitive detection samples according to the present invention.
The reference numbers are as follows:
1-support plate, 2-containing shell, 21-assembly hole, 22-medicine receiving port, 221-square through groove, 23-outflow port, 3-workbench, 31-first guide groove, 32-second guide groove, 321-transmission rod, 322-rotating wheel, 33-T-shaped sliding block, 34-support table, 341-first containing groove, 342-detection flat plate, 35-clamping block, 351-first spring, 352-support block, 4-mixing shaft, 41-threaded rod, 5-mixing component, 51-first mixing partition plate, 52-second mixing partition plate, 53-mixing groove, 54-second containing groove, 6-auxiliary component, 61-third guide groove, 62-second spring, 7-smearing component, 71-smearing rotating shaft, 72-cotton cloth, 8-fixing components, 81-assembling grooves, 82-supporting shafts, 83-arc-shaped clamping blocks, 84-torsion springs and 9-supporting legs.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
The invention will be further illustrated with reference to the following figures 1 to 7 and examples:
in the embodiment, as shown in fig. 1 to 7, a sampling, preprocessing and mixing device for drug sensitive detection samples comprises a supporting plate 1, a receiving casing 2 and a workbench 3 are fixedly connected to one side of the supporting plate 1, the receiving casing 2 is made of transparent material, the workbench 3 is arranged below the receiving casing 2, an assembly hole 21 is formed in the upper end of the receiving casing 2, a mixing shaft 4 is rotatably arranged in the assembly hole 21, a thread is arranged inside a hole in the mixing shaft 4, a threaded rod 41 is arranged in the mixing shaft 4, a mixing component 5 is fixedly arranged outside the mixing shaft 4, an auxiliary component 6 is arranged at the end of the mixing component 5, one side of the receiving casing 2 is fixedly arranged on the supporting plate 1, a drug receiving port 22 is fixedly arranged on the other side of the receiving casing 2, a square through hole 221 is formed in the drug receiving port 22, and the square through hole 221 is communicated with the interior of the receiving casing 2, an outflow port 23 is fixedly arranged below the accommodating shell 2, a smearing component 7 is arranged below the outflow port 23, fixing components 8 are arranged at two end parts of the smearing component 7, a first guide groove 31 and a second guide groove 32 are arranged on the workbench 3, the second guide groove 32 is arranged at one side of the first guide groove 31, the first guide groove 31 is communicated with the second guide groove 32, a T-shaped sliding block 33 is arranged in the first guide groove 31 in a sliding manner, a support table 34 is fixedly connected to the upper surface of the T-shaped sliding block 33, a first accommodating groove 341 is arranged at one end of the support table 34, a detection flat plate 342 is arranged at the other end of the support table, clamping blocks 35 are arranged at two sides of the detection flat plate 342, a first spring 351 is fixedly arranged at one side of the clamping blocks 35, a support block 352 is fixedly arranged at the end part of the first spring 351, and the support block 352 is fixedly arranged on the upper surface of the support table 34, a transmission rod 321 is arranged in the second guide groove 32, the smearing component 7 is arranged on the transmission rod 321, a rotating wheel 322 is arranged on one side of the lower side of the transmission rod 321, the rotating wheel 322 is rotatably arranged in the second guide groove 32, one side of the rotating wheel 322 is in close contact with the T-shaped sliding block 33, and the other side of the rotating wheel is in close contact with the transmission rod 321. Firstly, a certain amount of normal saline is poured into the accommodating shell 2 through the medicine receiving port 22, at this time, the medicine receiving port 22 is arranged at the lower half part of the accommodating shell 2, the normal saline with the same height as that in the accommodating shell 2 is arranged in the medicine receiving port 22, then the inoculating loop subjected to burning sterilization is used for taking bacterial colonies to be detected, the bacterial colonies at the end part of the inoculating loop are placed in the normal saline after being inserted into the medicine receiving port 22, the threaded rod 41 is pulled, under the action of screw transmission, the mixing shaft 4 and the first mixing partition plate 51 and the second mixing partition plate 52 fixedly connected with the mixing shaft are rotated, the normal saline in the accommodating shell 2 is stirred, the process can not only promote the bacterial colonies at the end part of the inoculating loop to be dissolved into the saline, but also, a second spring 62 is arranged in a third guide groove 61 arranged on the first mixing partition plate 51, and the second spring 62 can apply a certain thrust to the second mixing partition plate 52 so as to be always attached to the inner wall of the accommodating shell 2, while rotating, the impurities remained on the inner wall of the accommodating shell 2 after the test can be cleaned, and the process is carried out simultaneously, the bacterial colony mixed by stirring flows downwards through the outflow port 23, the cotton cloth 72 is arranged at the bottom of the outflow port 23 to be soaked by the cotton cloth 72, the cotton cloth 72 is wound on the smearing rotating shaft 71 and is fixed by the fixing component 8, when the cotton cloth 72 needs to be replaced, only the arc-shaped clamping block 83 needs to be broken off, the replacement is convenient and quick, and is beneficial to sanitation, a proper detection flat plate 342 is selected, the clamping block 35 arranged on the supporting table 34 is pulled off, the detection flat plate 342 is clamped, as shown in the position of figure 1, the T-shaped sliding block 33 and the supporting table 34 fixedly arranged on the T-shaped sliding block are pushed along the first guide groove 31, meanwhile, the T-shaped sliding block 33 drives the rotating wheel 322 to rotate, the rotating wheel 322 drives the transmission rod 321 to move, but the transmission rod 321 and the T-shaped sliding block 33 move in opposite directions, the transfer line 321 drives again and paints pivot 71 clockwise rotation, along with detecting dull and stereotyped 342 and removing along first guide way 31, the arrival continues to move when painting pivot 71 department, paint pivot 71 direction of rotation this moment and can with detect dull and stereotyped 342 moving direction opposite, this process not only is of value to and evenly paints the bacterial colony that awaits measuring on detecting dull and stereotyped 342 greatly, make the test result more accurate, and, shortened greatly and paint the bacterial colony time, the efficiency is improved, will detect dull and stereotyped 342 and push away and paint pivot 71 after, pull back to figure 1 position again, paste the filter paper piece of antibiotic medicine on detecting dull and stereotyped 342 afterwards, then, wait to observe the size of antibacterial circle can.
In this embodiment, the mixing assembly 5 includes a first mixing partition plate 51 and a second mixing partition plate 52, the first mixing partition plate 51 is fixedly disposed at the outer side of the mixing shaft 4, the second mixing partition plate 52 is disposed at one side of the first mixing partition plate 51, a mixing groove 53 is formed in the first mixing partition plate 51, the mixing groove 53 extends downward to the bottom of the first mixing partition plate 51, a second accommodating groove 54 is formed in the end portion of the second mixing partition plate 52, and the second accommodating groove 54 penetrates through the upper and lower surfaces of the second mixing partition plate 52. Pulling the threaded rod 41, under the action of the screw transmission, the mixing shaft 4 and the first mixing partition 51 and the second mixing partition 52 fixedly connected thereto will rotate, and the physiological saline in the accommodating shell 2 will be stirred, and the bacterial colony at the end of the inoculating loop will be promoted to be dissolved into the saline.
In this embodiment, the auxiliary assembly 6 includes a third guide groove 61, the third guide groove 61 is opened at one side of the first mixing partition plate 51, a second spring 62 is fixedly disposed in the third guide groove 61, and a second mixing partition plate 52 is fixedly disposed at one side of the second spring 62. A second spring 62 is arranged in a third guide groove 61 formed in the first mixing partition plate 51, and the second spring 62 applies a certain thrust to the second mixing partition plate 52 to enable the second mixing partition plate to be always attached to the inner wall of the accommodating shell 2, so that impurities remained on the inner wall of the accommodating shell 2 through tests can be cleaned while the second mixing partition plate rotates.
In this embodiment, the smearing component 7 includes a smearing rotating shaft 71, one end of the smearing rotating shaft 71 is rotatably disposed on one side of the supporting plate 1, the other end of the smearing rotating shaft 71 is disposed on the transmission rod 321, a cotton cloth 72 is wound on the smearing rotating shaft 71, and the cotton cloth 72 is in close contact with the lower surface of the outflow port 23. The bacterial colony through the stirring mixture can flow downwards through egress opening 23, set up cotton 72 department and soak cotton 72 to egress opening 23 bottom, promote T shape slider 33 and the supporting bench 34 of fixed setting on it along first guide way 31, this simultaneously, T shape slider 33 drives the runner 322 rotatory, runner 322 drives the motion of transfer line 321 again, but transfer line 321 and T shape slider 33 direction of motion are opposite, transfer line 321 drives again and paints pivot 71 clockwise rotation, along with detecting dull and stereotyped 342 and removing along first guide way 31, it moves to reach and continues when painting pivot 71 department, it can be opposite with detection dull and stereotyped 342 moving direction to paint pivot 71 direction of rotation this moment, this process not only is of value to evenly paint the bacterial colony that awaits measuring on detecting dull and stereotyped 342 greatly, make the test result more accurate, moreover, the bacterial colony time of paining has been shortened greatly, and efficiency is improved.
In this embodiment, the fixing assembly 8 includes an assembly groove 81, the assembly groove 81 is opened on the smearing rotating shaft 71, a support shaft 82 is fixedly disposed in the assembly groove 81, an arc-shaped clamping block 83 and a torsion spring 84 are disposed on the support shaft 82, the torsion spring 84 is disposed in the arc-shaped clamping block 83, and a clamping surface of the arc-shaped clamping block 83 is arc-shaped. This fixed subassembly 8 sets up on paining pivot 71, can carry out the centre gripping to the winding cotton 72 on paining pivot 71 under the torsional spring 84 effect, makes cotton 72 can realize paining the action, and arc clamp splice 83 clamping face adopts the arc, can better laminating paint pivot 72, and it is more firm to let the centre gripping, when needing to change cotton 72, only need break off with the fingers and thumb arc clamp splice 83 can, change convenient and fast is favorable to the health.
In this embodiment, the lower surface of the outflow port 23 is arc-shaped, the corners of the support plate 1 are in arc transition, the lower surface of the worktable 3 is fixedly provided with the support legs 9, and the contact positions of the T-shaped slider 33 and the rotating wheel 322, the rotating wheel 322 and the transmission rod 321, and the transmission rod 321 and the smearing rotating shaft 71 are made of rough materials. The arc transition at the edge of the supporting plate 1 is favorable for safety, and the contact parts of the T-shaped sliding block 33 and the rotating wheel 322, the rotating wheel 322 and the transmission rod 321 and the smearing rotating shaft 71 are made of rough materials, so that the friction force can be increased, and the transmission effect is improved.
The invention has the beneficial effects that:
the threaded rod 41 is pulled, under the action of threaded transmission, the mixing shaft 4 and the first mixing partition plate 51 and the second mixing partition plate 52 fixedly connected with the mixing shaft are rotated, the normal saline in the accommodating shell 2 is stirred, and bacterial colonies at the end part of the inoculating loop can be promoted to be dissolved into the saline in the process;
a second spring 62 is arranged in a third guide groove 61 formed in the first mixing partition plate 51, and the second spring 62 can apply a certain thrust to the second mixing partition plate 52 to enable the second mixing partition plate to be always attached to the inner wall of the accommodating shell 2, and can clean impurities remained on the inner wall of the accommodating shell 2 after tests while rotating;
the colonies mixed by stirring can flow downwards through the outflow port 23, the cotton cloth 72 is soaked at the position where the cotton cloth 72 is arranged at the bottom of the outflow port 23, the T-shaped sliding block 33 and the support table 34 fixedly arranged on the T-shaped sliding block 33 are pushed along the first guide groove 31, meanwhile, the T-shaped sliding block 33 drives the rotating wheel 322 to rotate, the rotating wheel 322 drives the transmission rod 321 to move, the transmission rod 321 and the T-shaped sliding block 33 are opposite in moving direction, the transmission rod 321 drives the smearing rotating shaft 71 to rotate clockwise, the smearing rotating shaft 71 continues to move when reaching the smearing rotating shaft 71 along with the movement of the detection flat plate 342, and the rotating direction of the smearing rotating shaft 71 is opposite to the moving direction of the detection flat plate 342, so that the bacterial colonies to be detected can be smeared on the detection flat plate 342 uniformly, the test result is more accurate, the bacterial colony smearing time is greatly shortened, and the efficiency is improved;
this fixed subassembly 8 sets up on paining pivot 71, can carry out the centre gripping to the winding cotton 72 on paining pivot 71 under the torsional spring 84 effect, makes cotton 72 can realize paining the action, and arc clamp splice 83 clamping face adopts the arc, can better laminating paint pivot 72, and it is more firm to let the centre gripping, when needing to change cotton 72, only need break off with the fingers and thumb arc clamp splice 83 can, change convenient and fast is favorable to the health.
The working principle is as follows:
firstly, a certain amount of normal saline is poured into the accommodating shell 2 through the medicine receiving port 22, at this time, the medicine receiving port 22 is arranged at the lower half part of the accommodating shell 2, the normal saline with the same height as that in the accommodating shell 2 is arranged in the medicine receiving port 22, then the inoculating loop subjected to burning sterilization is used for taking bacterial colonies to be detected, the bacterial colonies at the end part of the inoculating loop are placed in the normal saline after being inserted into the medicine receiving port 22, the threaded rod 41 is pulled, under the action of screw transmission, the mixing shaft 4 and the first mixing partition plate 51 and the second mixing partition plate 52 fixedly connected with the mixing shaft are rotated, the normal saline in the accommodating shell 2 is stirred, the process can not only promote the bacterial colonies at the end part of the inoculating loop to be dissolved into the saline, but also, a second spring 62 is arranged in a third guide groove 61 arranged on the first mixing partition plate 51, and the second spring 62 can apply a certain thrust to the second mixing partition plate 52 so as to be always attached to the inner wall of the accommodating shell 2, while rotating, the impurities remained on the inner wall of the accommodating shell 2 after the test can be cleaned, and the process is carried out simultaneously, the bacterial colony mixed by stirring flows downwards through the outflow port 23, the cotton cloth 72 is arranged at the bottom of the outflow port 23 to be soaked by the cotton cloth 72, the cotton cloth 72 is wound on the smearing rotating shaft 71 and is fixed by the fixing component 8, when the cotton cloth 72 needs to be replaced, only the arc-shaped clamping block 83 needs to be broken off, the replacement is convenient and quick, and is beneficial to sanitation, a proper detection flat plate 342 is selected, the clamping block 35 arranged on the supporting table 34 is pulled off, the detection flat plate 342 is clamped, as shown in the position of figure 1, the T-shaped sliding block 33 and the supporting table 34 fixedly arranged on the T-shaped sliding block are pushed along the first guide groove 31, meanwhile, the T-shaped sliding block 33 drives the rotating wheel 322 to rotate, the rotating wheel 322 drives the transmission rod 321 to move, but the transmission rod 321 and the T-shaped sliding block 33 move in opposite directions, the transfer line 321 drives again and paints pivot 71 clockwise rotation, along with detecting dull and stereotyped 342 and removing along first guide way 31, the arrival continues to move when painting pivot 71 department, paint pivot 71 direction of rotation this moment and can with detect dull and stereotyped 342 moving direction opposite, this process not only is of value to and evenly paints the bacterial colony that awaits measuring on detecting dull and stereotyped 342 greatly, make the test result more accurate, and, shortened greatly and paint the bacterial colony time, the efficiency is improved, will detect dull and stereotyped 342 and push away and paint pivot 71 after, pull back to figure 1 position again, paste the scraps of paper on detecting dull and stereotyped 342, then, wait to observe the size of antibacterial circle can.
The embodiments of the present invention are disclosed as the preferred embodiments, but not limited thereto, and those skilled in the art can easily understand the spirit of the present invention and make various extensions and changes without departing from the spirit of the present invention.
Claims (7)
1. The utility model provides a quick sample sampling preliminary treatment mixing arrangement that detects of medicine, includes backup pad (1), its characterized in that, one side fixedly connected with holding casing (2) and workstation (3) of backup pad (1), be provided with workstation (3) below holding casing (2), pilot hole (21) have been seted up to the upper end of holding casing (2), and this pilot hole (21) internal rotation is provided with mixing shaft (4), and mixing shaft (4) mesopore inside is provided with the screw thread, is provided with threaded rod (41) in this mixing shaft (4), the fixed mixed subassembly (5) that is provided with in the outside of mixing shaft (4), the tip of this mixed subassembly (5) is provided with auxiliary assembly (6), one side of holding casing (2) is fixed to be set up on backup pad (1), and the fixed medicine mouth (22) that is provided with of opposite side.
2. A drug sensitive assay sample pre-processing mixing device as claimed in claim 1, wherein: the medicine receiving port (22) is provided with a square through hole (221), the square through hole (221) is communicated with the inside of the accommodating shell (2), an outflow port (23) is fixedly arranged below the accommodating shell (2), a smearing component (7) is arranged below the outflow port (23), fixing components (8) are arranged at two end parts of the smearing component (7), the workbench (3) is provided with a first guide groove (31) and a second guide groove (32), the second guide groove (32) is arranged at one side of the first guide groove (31), the first guide groove (31) is communicated with the second guide groove (32), the first guide groove (31) is internally provided with a T-shaped sliding block (33) in a sliding manner, a supporting table (34) is fixedly connected to the upper surface of the T-shaped sliding block (33), one end of the supporting table (34) is provided with a first accommodating groove (341), and the other end of the supporting table is provided with a detection flat plate (342), the two sides of the detection panel (342) are provided with clamping blocks (35), one side of each clamping block (35) is fixedly provided with a first spring (351), the end part of each first spring (351) is fixedly provided with a supporting block (352), each supporting block (352) is fixedly arranged on the upper surface of the corresponding supporting table (34), a transmission rod (321) is arranged in each second guide groove (32), a smearing component (7) is arranged on each transmission rod (321), a rotating wheel (322) is arranged on one side below each transmission rod, each rotating wheel (322) is rotatably arranged in each second guide groove (32), one side of each rotating wheel (322) is in close contact with a T-shaped sliding block (33), and the other side of each rotating wheel (322) is in close contact with the transmission rod (321).
3. A drug sensitive assay sample pre-processing mixing device as claimed in claim 2, wherein: mix subassembly (5) including first mixed baffle (51) and second mixed baffle (52), first mixed baffle (51) are fixed to be set up in the outside of mixing axle (4), second mixed baffle (52) set up in one side of first mixed baffle (51), mixing tank (53) have been seted up on first mixed baffle (51), and this mixing tank (53) downwardly extending to first mixed baffle (51) bottom, second storage tank (54) have been seted up to the tip of second mixed baffle (52), and surface about this second storage tank (54) runs through second mixed baffle (52).
4. A drug sensitive assay sample pre-processing mixing device as claimed in claim 3, wherein: the auxiliary assembly (6) comprises a third guide groove (61), the third guide groove (61) is formed in one side of the first mixing partition plate (51), a second spring (62) is fixedly arranged in the third guide groove (61), and a second mixing partition plate (52) is fixedly arranged on one side of the second spring (62).
5. A pre-processing mixing device for sampling of drug sensitive assay samples as claimed in claim 4, wherein: scribble subassembly (7) including scribbling pivot (71), should scribble pivot (71) one end and rotate and set up in one side of backup pad (1), the other end sets up on transfer line (321), it is provided with cotton (72) to scribble the winding on pivot (71), this cotton (72) and egress opening (23) lower surface in close contact with.
6. A pre-processing mixing device for sampling of drug sensitive assay samples as claimed in claim 5, wherein: the fixing assembly (8) comprises an assembling groove (81), the assembling groove (81) is arranged on the smearing rotating shaft (71), a supporting shaft (82) is fixedly arranged in the assembling groove (81), an arc-shaped clamping block (83) and a torsion spring (84) are arranged on the supporting shaft (82), the torsion spring (84) is arranged in the arc-shaped clamping block (83), and a clamping surface of the arc-shaped clamping block (83) is arc-shaped.
7. A drug sensitive assay sample pre-processing mixing device as claimed in claim 6, wherein: the lower surface of egress opening (23) is the arc, the equal circular arc transition of backup pad (1) corner, the lower fixed landing leg (9) that is provided with of workstation (3).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
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