CN114796162A

CN114796162A - Plaster for treating bone fracture and arthralgia and myalgia and preparation method thereof

Info

Publication number: CN114796162A
Application number: CN202210421893.1A
Authority: CN
Inventors: 李亲照
Original assignee: Individual
Current assignee: Individual
Priority date: 2022-04-21
Filing date: 2022-04-21
Publication date: 2022-07-29

Abstract

The invention relates to a plaster for treating bone fracture and arthralgia and myalgia and a preparation method thereof, wherein the plaster comprises the following raw material medicines by weight: 15-30 g of nux vomica, 40-60 g of musk, 40-60 g of dragon's blood, 60-90 g of safflower, 60-90 g of ground beetle, 40-60 g of frankincense, 40-60 g of myrrh, 30-60 g of elephant skin, 60-90 g of garden balsam stem, 30-60 g of keel, 15-30 g of native copper, 10-15 g of pseudo-ginseng, 60-90 g of Chinese angelica, 80-90 g of teasel root, 50-60 g of rhizoma drynariae and 5-10 g of borneol. The formula is prepared by reasonable compatibility, has the effects of promoting blood circulation, removing blood stasis, relieving swelling, relaxing muscles and tendons, dredging collaterals and relieving pain, can quickly relieve pain for diseases such as limb joint fracture, injured tendons, soft tissue injury, cervical, thoracic and lumbar disc herniation and the like, has good treatment effect, and especially has obvious curative effect on bone injury diseases of long-term bone and muscle pain and old injury which are not healed and are newly injured.

Description

Plaster for treating bone fracture and arthralgia and myalgia and preparation method thereof

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a plaster for treating bone fracture and arthralgia and myalgia and a preparation method thereof.

Background

Fracture refers to the continuous complete or partial fracture of bone structure, which is often seen in children and the elderly, and also occurs in young and middle-aged people, and patients often have one-part fracture and a few multiple fractures, and the fracture is divided into the following parts according to the physical manifestations of different periods after fracture: hematoma formation, fibrous callus formation, bony callus formation, and callus remodeling or remodeling. In general, through the above steps, the fractured part is restored to the same structure as the original bone tissue, and the complete healing is achieved.

Lack of exercise and incorrect posture causes muscle and bone pain, which is a common defect of the old, and starts to spread among young and middle-aged people. Neck pain occurs when sitting in front of the computer for a whole day; lumbago due to long-term standing in the air-conditioned room; the mouse is used too much, and the wrist is painful; occasional swimming, shoulder pain; mountain climbing leading to knee pain. The "muscles and bones" of the young become the special characters of many young and middle-aged people.

The treatment of bone injury and arthralgia and myalgia generally adopts external treatment method, because its curative effect is obvious, easy to master, the price is cheap, become the most common therapy of bone injury treatment, can divide into applying ointment, applying and rubbing medicine, fumigation and washing wet dressing medicine and hot compress medicine according to the formulation, wherein the applying ointment plays an important role in all external treatment medicines with its definite curative effect, convenient use, abundant type. The most obvious disease symptoms, no matter bone fracture or muscle and bone pain, are pain, and have the advantages of long duration, long treatment time, low cure effect and easy repetition, thereby not only reducing the early treatment effect, but also even aggravating the disease symptoms and increasing the pain of patients. The existing plaster for treating bone injuries and arthralgia and myalgia has good effects on treating corresponding bone injuries and arthralgia and myalgia, but has poor treatment effects on bone injuries such as bone and myalgia which are not treated for a long time and bone injuries which are not healed and are newly injured.

Disclosure of Invention

The invention aims to provide a plaster for treating bone injuries and arthralgia and myalgia and a preparation method thereof, so as to provide the plaster capable of quickly relieving pain symptoms of the bone injuries and the arthralgia and myalgia, and particularly has obvious curative effect on bone injuries with long-term disability of treating the bone injuries and the pains of old injuries and new injuries.

In order to achieve the purpose, the invention adopts the following technical scheme:

a plaster for treating bone fracture and arthralgia and myalgia and a preparation method thereof are disclosed, which comprises the following raw material medicines by weight: 15-30 g of nux vomica, 40-60 g of musk, 40-60 g of dragon's blood, 60-90 g of safflower, 60-90 g of ground beetle, 40-60 g of frankincense, 40-60 g of myrrh, 30-60 g of elephant skin, 60-90 g of garden balsam stem, 30-60 g of keel, 15-30 g of native copper, 10-15 g of pseudo-ginseng, 60-90 g of Chinese angelica, 80-90 g of teasel root, 50-60 g of rhizoma drynariae and 5-10 g of borneol.

Further, the medicine comprises the following raw material medicines by weight: 20g of nux vomica, 50g of musk, 45g of dragon's blood, 65g of safflower, 70g of eupolyphaga, 50g of frankincense, 50g of myrrh, 35g of elephant skin, 60g of garden balsam stem, 35g of dragon bone, 15g of native copper, 12g of pseudo-ginseng, 60g of Chinese angelica, 80g of teasel root, 55g of drynaria rhizome and 8g of borneol.

A preparation method of the plaster comprises the following preparation steps:

s1, treatment of the medicine materials: one or more of rhizoma drynariae, teasel root and ground beetle; one or more of radix Angelicae sinensis, semen Strychni, and corium Elephatis; one or more of herba speranskiae tuberculatae and Moschus; pulverizing Os Draconis, radix Dipsaci, and Pyritum, and mixing; one or more of safflower, notoginseng, frankincense and myrrh, and borneol fine material are processed and sieved by a 120-mesh sieve, and fine powder is sieved for standby;

s2, soaking the medicines: mixing the sesame oil and the medicines in the step S1 according to the ratio of 2-5: 1, and soaking for later use;

s3, frying and extracting: heating oil, adding the medicinal materials, frying with slow fire, stirring to make the medicinal materials uniformly heated, frying to the required degree, removing residue, and filtering to obtain ointment oil;

s4, oil refining: refining oil with medium and small fire for about 4-6 hr, continuously stirring the medicinal oil with a stick, and refining oleum Sesami with explosive to obtain 60-70% residue;

s5, adding yellow lead: adding Plumbum Preparatium, stirring slowly and rapidly to generate a large amount of white dense smoke, and boiling vigorously; boiling, spraying cold water into the oil pan for 3-4 times, fanning, stirring continuously to disperse smoke and eliminate rolling bubbles, decocting with slow fire until the oil color turns black, dipping a little ointment with a wooden stick, dripping into cold water, and taking out oil drop with fingers to knead the oil drop to be tender and proper if the oil drop is made into a ball;

s6, old tender test: the ointment is suitable for summer, and when the ointment is too old, sesame oil with one tenth of the weight of the ointment is added and continuously boiled until the ointment is proper;

s7, removing fire toxin: after the plaster is formed, spraying cold water into a plaster pot, namely, the black smoke comes out, then twisting the plaster into small lumps, soaking the small lumps in the cold water for 3-10 days, and changing the water 1-2 times every day; s8, preparing a patch: adding water into a small pot in a big pot to completely melt the plaster, heating with direct fire to boil off water in the plaster until no bubbles and no foam exist, stopping heating, slightly cooling, adding pulverized fine powders of Carthami flos, Notoginseng radix, Olibanum, Myrrha, sanguis Draxonis, and Borneolum, and stirring to obtain spread plaster;

s9, spreading ointment: the plaster which is not cooled is rolled up by bamboo chopsticks, the cloth is spread out, the plaster is well spread from the center to the periphery along with the size of the cloth, and finally the plaster is formed by folding.

Further, the soaking time in the S2 is 7-8 days.

Furthermore, the sesame oil added in the S6 accounts for 8-12% of the weight of the ointment.

Further, the soaking time in the S7 is 3-10 days.

The invention has the beneficial effects that:

a plaster for treating bone fracture and arthralgia and myalgia and a preparation method thereof are disclosed, which comprises the following raw material medicines by weight: 15-30 g of nux vomica, 40-60 g of musk, 40-60 g of dragon's blood, 60-90 g of safflower, 60-90 g of ground beetle, 40-60 g of frankincense, 40-60 g of myrrh, 30-60 g of elephant skin, 60-90 g of garden balsam stem, 30-60 g of keel, 15-30 g of native copper, 10-15 g of pseudo-ginseng, 60-90 g of Chinese angelica, 80-90 g of teasel root, 50-60 g of rhizoma drynariae and 5-10 g of borneol. The traditional Chinese medicine composition directly acts on skin, permeates skin to directly reach a focus, bypasses the first pass effect of liver without gastrointestinal absorption, thereby avoiding the occurrence of the condition of drug effect reduction, has good treatment effect on diseases such as limb joint fracture, injured tendons, soft tissue injury, cervical, thoracic and lumbar disc herniation and the like, particularly has obvious treatment effect on bone injury diseases of long-term bone and muscle pain and old injury which are not healed and then are newly injured, and the clinical cure rate reaches 98%.

Detailed Description

In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention.

Example 1:

a plaster for treating bone fracture and arthralgia and myalgia comprises the following raw material medicines by weight: 20g of nux vomica, 50g of musk, 45g of dragon's blood, 65g of safflower, 70g of eupolyphaga, 50g of frankincense, 50g of myrrh, 35g of elephant skin, 60g of garden balsam stem, 35g of dragon bone, 15g of native copper, 12g of pseudo-ginseng, 60g of Chinese angelica, 80g of teasel root, 55g of drynaria rhizome and 8g of borneol.

The raw material medicaments are prepared by the following steps:

s1, treatment of the medicine materials: pulverizing rhizoma Drynariae, radix Dipsaci, Eupolyphaga Seu Steleophaga, radix Angelicae sinensis, semen Strychni, corium elephatis, caulis et folium Gaultheriae Yunnanensis, Moschus, Os Draconis, radix Dipsaci, and Pyritum, mixing, processing fine materials of Carthami flos, Notoginseng radix, Olibanum, Myrrha, and Borneolum, sieving with 120 mesh sieve, and sieving fine powder.

S2, soaking medicine: mixing the sesame oil with the medicines in the step S1 according to the weight ratio of 4: 1, and soaking for 7 days for later use.

S3, frying and extracting: heating oil, adding the medicinal materials, frying with slow fire, stirring to make the medicinal materials uniformly heated, frying to the required degree, removing residue, and filtering to obtain ointment.

S4, oil refining: refining oil with medium and small fire for about 5 hr, continuously stirring the medicinal oil with a stick, and refining oleum Sesami with explosive to obtain 65% residue.

S5, adding yellow lead: adding Plumbum Preparatium, stirring slowly and rapidly to generate a large amount of white dense smoke, and boiling vigorously; the oil is boiled with small fire until the oil color turns black, a wooden stick is dipped in a little of ointment and is dripped into the cold water, and when the oil drops become beads, the oil beads are fished by fingers to be tender and suitable for cooking.

The weight ratio of the oil liquid to the yellow lead is about 1:0.5, the purpose of adding the lead is to play a role of an adhesive, and one of the important reasons that the traditional plaster has stronger drug effect than the plaster prepared by the modern process is to use the lead. The yellow lead is also called as the minium, the lead is a traditional Chinese medicine, and the effective components of the plaster can be more closely contacted with pores through the combination with the lead, quickly permeate the pores and enter the blood circulation near the affected part; the plaster prepared by the modern process is beautiful, a glue is used, the active ingredients of the plaster are prevented from being rapidly and completely absorbed, and the plaster prepared by the modern process has small medicinal potency, so that the work of the plaster prepared by the modern process is greatly reduced. The color of the pill begins to turn into dark red, and the pill needs to be slowly refined until the red color is completely faded, so that the toxicity in the pill is not completely dissolved.

The proportion of yellow lead is generally calculated according to 195 g of yellow lead used per 500 g of oil, and the season is noted (yellow lead can be used up to 240 g in summer, only 140 g in winter, and 210 g in spring and autumn are suitable). Empirically, the weight ratio of the oil pill 16: 7, one jin of sesame oil is used with four to five two pills, the four pills are tender in winter and the five pills are old in summer. The lower part of the fire is divided into the upper part and the lower part of the fire is divided into the upper part and the lower part of the fire. The former is continuously boiled with slow fire, the fried lead is slowly put into the boiling oil, continuously and clockwise stirred with a locust stick or a willow stick and a mulberry stick, bubbles are overflowed on the oil, dense smoke is emitted, when smoke is exhausted slightly, three or four drops of oil are dropped on cold water by bamboo chopsticks, the oil is slightly beaded and does not scatter, the beads are taken to wipe clean water, the water is kneaded by dry hands until the hands are sticky but not greasy, the fire is quickly stopped, or the pot is lifted away from a stove, and the mixture is continuously stirred for cooling. Discharging the pills after leaving the fire, namely discharging the pills after the refined medicinal oil leaves the stove.

S6, old tender test: the tenderness of the plaster is difficult to master, and generally the plaster should be decocted tenderly in winter and older in summer. The experimental method comprises the following steps: the ointment is tender, the tender ointment is most suitable in winter, the ointment should be decocted for a few minutes in summer, if the oil drops are kneaded, the ointment feels hard and is not sticky, the elastic ointment is immediately broken, the brittleness is higher, the ointment is older, the ointment is suitable for summer, and when the ointment is too old, sesame oil which is one tenth of the weight of the ointment is added and is continuously decocted until the ointment is tender and suitable. The size and duration of the fire and the experimental tenderness are the key points for decocting the herbs.

S7, removing fire toxin: after the plaster is prepared, spraying cold water into a plaster pot, namely, the black smoke emerges, then twisting the plaster into small lumps, soaking the small lumps in the cold water for 8 days, and changing the water 1 or 2 times every day.

S8, preparing a patch: the plaster after fire toxin is removed is heated by covering a pot in a pot and separating water, namely the plaster is put in a small pot added with water in a big pot, the plaster is heated by direct fire after being completely melted so as to decoct the water in the plaster until no bubbles or foam exists, the fire is stopped, the plaster is cooled slightly, and the pulverized and standby fine powder of safflower, pseudo-ginseng, frankincense, myrrh, dragon's blood and borneol is added to be stirred uniformly, thus the plaster can be spread.

Example 2:

a plaster for treating bone fracture and arthralgia and myalgia comprises the following raw material medicines by weight: 15g of nux vomica, 40g of musk, 40g of dragon's blood, 60g of safflower, 60g of eupolyphaga, 40g of frankincense, 40g of myrrh, 30g of elephant skin, 60g of garden balsam stem, 30g of dragon bone, 15g of native copper, 10g of pseudo-ginseng, 60g of Chinese angelica, 80g of teasel root, 50g of drynaria rhizome and 5g of borneol.

The raw material medicaments are prepared by the following steps:

S2, soaking the medicines: mixing the sesame oil with the medicines of the step S1 according to the ratio of 2: 1, and soaking for 6 days for later use.

S4, oil refining: refining oil with medium and small fire for about 4 hr, continuously stirring the medicinal oil with a stick, and refining oleum Sesami with explosive to obtain 60% residue.

s6, old tender test: the tenderness of the plaster is difficult to master, and generally the plaster should be decocted tenderly in winter and older in summer. The experimental method comprises the following steps: the ointment is suitable for summer, and when the ointment is too old, sesame oil with one tenth of the weight of the ointment is added to continuously boil until the ointment is too soft and suitable. The size and duration of the fire and the experimental tenderness are the key points for decocting the herbs.

S7, removing fire toxin: after the plaster is formed, spraying cold water into a plaster pot, namely, the black smoke emerges, then twisting the plaster into small lumps, soaking the small lumps in the cold water for 6 days, and changing the water 1 time every day.

Example 3:

a plaster for treating bone fracture and arthralgia and myalgia comprises the following raw material medicines by weight: 30g of nux vomica, 60g of musk, 60g of dragon's blood, 90g of safflower, 90g of ground beetle, 60g of frankincense, 60g of myrrh, 60g of elephant skin, 90g of garden balsam stem, 60g of dragon bone, 30g of native copper, 15g of pseudo-ginseng, 90g of Chinese angelica, 90g of teasel root, 60g of drynaria rhizome and 10g of borneol.

The raw material medicaments are prepared by the following steps:

s1, treatment of the medicine materials: pulverizing rhizoma Drynariae, radix Dipsaci, Eupolyphaga Seu Steleophaga, radix Angelicae sinensis, semen Strychni, corium elephatis, caulis et folium Gaultheriae Yunnanensis, Moschus, Os Draconis, radix Dipsaci, and Pyritum, mixing, processing fine materials of Carthami flos, Notoginseng radix, Olibanum, Myrrha, and Borneolum, sieving with 120 mesh sieve, and sieving fine powder. S2, soaking the medicines: mixing the sesame oil with the medicines in the step S1 according to the weight ratio of 5: 1, and soaking for 7 days for later use.

S4, oil refining: refining oil with medium and small fire for about 6 hr, continuously stirring the medicinal oil with a stick, and refining oleum Sesami with explosive to obtain 70% residue.

S5, adding yellow lead, stirring slowly and quickly, generating a large amount of white dense smoke at the moment, and boiling violently; the oil is boiled with small fire until the oil color turns black, a wooden stick is dipped in a little of ointment and is dripped into the cold water, and when the oil drops become beads, the oil beads are fished by fingers to be tender and suitable for cooking.

S7, removing fire toxin: spraying cold water into the plaster pan after the plaster is formed, namely, black smoke emerges, twisting the plaster into small lumps, soaking in the cold water for 8 days, and changing the water 1 or 2 times a day.

In other embodiments, one or more medicines can be selected from the medicines in the formula, the fundamental principle of the formula is not changed, and similar effects can be achieved, but the more the selected medicines are, the more reasonable the medicine combination formula is, the more remarkable the curative effect is, the optimal formula is when the formula is the combination of all the medicines, and the details of the embodiment of preparing the plaster by adding and subtracting the combination of the same medicines are not repeated herein.

The plaster prepared by the invention has a treatment course of 7 days, pain is relieved in 2-3 days, generally, the pain of a patient with a lighter disease is obviously relieved after the patient takes the plaster for one treatment course, the patient with a heavier disease is cured in 2-3 treatment courses, the patient with the heavier disease is basically cured in 4-5 treatment courses, and the clinical cure rate reaches 98%.

The dosage, indications and effects of the plaster of the invention are explained in detail below in connection with clinical treatment cases:

case 1:

the patients: li Shi, female 52 years old, 8 months and 20 days in 2019. The pain of the right ankle joint caused by the trauma is complained and attacks repeatedly, the pain is relieved after the plaster is applied for three days, and the pain is not developed until now after 7 days as a treatment course.

Case 2:

the patients: wenyao, male, 60 years old, 13 days of 12 months and 13 years old in 2019, chief complaints are neck and shoulder pain, upper limbs are cool, neck is radiated to fingertips like an electric shock, head and neck are aggravated obviously when rotating, and the disease is improved after 2 courses of application, which is not found until now.

Case 3:

the patients: wangzhi, female, age 63, diagnosed in 2020, 03 and 10 days, DR shows in the left wrist of hospital: the distal radius fracture can be aligned. And (3) diagnosis: fracture of the radius. The local pain and swelling subsided after 5 days of application. 2, the patient can move after treatment period, and the left wrist DR is rechecked: local callus formation is recommended to be added for 1-2 courses of treatment.

The present invention is not limited to the above-mentioned preferred embodiments, and any other products in various forms can be obtained by anyone in the light of the present invention, but any changes in the shape or structure thereof, which have the same or similar technical solutions as those of the present application, fall within the protection scope of the present invention.

Claims

1. A plaster for treating bone fracture and arthralgia and myalgia is characterized in that: comprises the following raw material medicines by weight: 15-30 g of nux vomica, 40-60 g of musk, 40-60 g of dragon's blood, 60-90 g of safflower, 60-90 g of ground beetle, 40-60 g of frankincense, 40-60 g of myrrh, 30-60 g of elephant skin, 60-90 g of garden balsam stem, 30-60 g of keel, 15-30 g of native copper, 10-15 g of pseudo-ginseng, 60-90 g of Chinese angelica, 80-90 g of teasel root, 50-60 g of rhizoma drynariae and 5-10 g of borneol.

2. The plaster for treating bone injuries and arthralgia and myalgia as claimed in claim 1, wherein: 20g of nux vomica, 50g of musk, 45g of dragon's blood, 65g of safflower, 70g of eupolyphaga, 50g of frankincense, 50g of myrrh, 35g of elephant skin, 60g of garden balsam stem, 35g of dragon bone, 15g of native copper, 12g of pseudo-ginseng, 60g of Chinese angelica, 80g of teasel root, 55g of drynaria rhizome and 8g of borneol.

3. A process for producing a plaster according to claim 1, which comprises: the preparation method comprises the following preparation steps:

s4, oil refining: refining oil with medium or small fire for about 4-6 hr, continuously stirring the medicinal oil with a stick, and refining oleum Sesami with explosive to obtain 60-70% residue;

s5, adding yellow lead: adding Plumbum Preparatium, stirring slowly and rapidly to generate a large amount of white dense smoke, and boiling vigorously; boiling in oil pan, spraying cold water into the oil pan for 3-4 times, fanning, stirring continuously to disperse smoke and eliminate bubble, decocting with slow fire until the oil color turns black, dipping a little ointment with a wooden stick, dripping into cold water, and taking out oil drop with fingers to knead the oil drop to be tender and proper if the oil drop becomes a ball;

s9, spreading ointment: the plaster which is not cooled is rolled up by bamboo chopsticks, the cloth is spread out, the plaster is slowly spread from the center to the periphery along with the size of the cloth, and finally the plaster is folded in half.

4. The production method according to claim 3, characterized in that: the soaking time in the S2 is 7-8 days.

5. The production method according to claim 3, characterized in that: the sesame oil added in the S6 accounts for 8-12% of the weight of the ointment.

6. The production method according to claim 3, characterized in that: the soaking time in the S7 is 3-10 days.