CN1147815A - 腺苷衍生物 - Google Patents

腺苷衍生物 Download PDF

Info

Publication number
CN1147815A
CN1147815A CN95192979A CN95192979A CN1147815A CN 1147815 A CN1147815 A CN 1147815A CN 95192979 A CN95192979 A CN 95192979A CN 95192979 A CN95192979 A CN 95192979A CN 1147815 A CN1147815 A CN 1147815A
Authority
CN
China
Prior art keywords
compound
formula
alkyl
methyladenosine
cyclohexyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN95192979A
Other languages
English (en)
Chinese (zh)
Inventor
F·加迪恩
B·L·K·曼戈
J·R·福扎德
M·法拉沙德
P·K·卡帕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9409324A external-priority patent/GB9409324D0/en
Priority claimed from GB9416693A external-priority patent/GB9416693D0/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of CN1147815A publication Critical patent/CN1147815A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CN95192979A 1994-05-10 1995-05-09 腺苷衍生物 Pending CN1147815A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB9409324A GB9409324D0 (en) 1994-05-10 1994-05-10 New organic compounds, their preparation and use
US24991494A 1994-05-26 1994-05-26
US08/249,914 1994-05-26
GB9416693A GB9416693D0 (en) 1994-08-18 1994-08-18 Improvements in or relating to organic compounds
GB9409324.2 1994-08-18
GB9416693.1 1994-08-18

Publications (1)

Publication Number Publication Date
CN1147815A true CN1147815A (zh) 1997-04-16

Family

ID=27267177

Family Applications (1)

Application Number Title Priority Date Filing Date
CN95192979A Pending CN1147815A (zh) 1994-05-10 1995-05-09 腺苷衍生物

Country Status (13)

Country Link
EP (1) EP0759925A1 (pt)
JP (1) JPH09512823A (pt)
CN (1) CN1147815A (pt)
AU (1) AU2546195A (pt)
BR (1) BR9507683A (pt)
CA (1) CA2186847A1 (pt)
CZ (1) CZ327896A3 (pt)
FI (1) FI964468A (pt)
HU (1) HUT75338A (pt)
NO (1) NO964735L (pt)
PL (1) PL316985A1 (pt)
SK (1) SK146096A3 (pt)
WO (1) WO1995030683A1 (pt)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100579533C (zh) * 2003-03-07 2010-01-13 剑桥生物工艺有限公司 治疗疼痛的化合物
US8252766B2 (en) 2002-12-09 2012-08-28 Cbt Development Limited Use of spongosine for the treatment of pain
CN108822174A (zh) * 2018-08-29 2018-11-16 上海兆维科技发展有限公司 新型核苷修饰物2’-eoe-鸟嘌呤核苷及其制备方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110902A (en) * 1997-06-23 2000-08-29 Moehler; Hanns Method for the inhibition of neuronal activity leading to a focal epileptic seizure by local delivery of adenosine
EP2021350B1 (en) 2006-03-21 2016-12-21 Rheinische Friedrich-Wilhelms-Universität Bonn Phosphorylated a2a receptor agonists

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8729994D0 (en) * 1987-12-23 1988-02-03 Glaxo Group Ltd Chemical compounds
GB2226027B (en) * 1988-12-13 1992-05-20 Sandoz Ltd Adenosine derivatives,their production and use
US5017578A (en) * 1989-06-09 1991-05-21 Hoechst-Roussel Pharmaceuticals Inc. N-heteroaryl-purin-6-amines useful as analgesic and anticonvulsant agents
HUT61567A (en) * 1990-12-07 1993-01-28 Sandoz Ag Process for producing new pharmaceutical compositions comprising 2'-o-alkyladenosine derivatives and for producing 6-cyclohexyl-2'-o-methyladenosinehydrate
DK62692D0 (pt) * 1992-05-14 1992-05-14 Novo Nordisk As

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8252766B2 (en) 2002-12-09 2012-08-28 Cbt Development Limited Use of spongosine for the treatment of pain
CN100579533C (zh) * 2003-03-07 2010-01-13 剑桥生物工艺有限公司 治疗疼痛的化合物
CN108822174A (zh) * 2018-08-29 2018-11-16 上海兆维科技发展有限公司 新型核苷修饰物2’-eoe-鸟嘌呤核苷及其制备方法

Also Published As

Publication number Publication date
EP0759925A1 (en) 1997-03-05
HUT75338A (en) 1997-05-28
HU9603105D0 (en) 1997-01-28
CZ327896A3 (en) 1997-03-12
CA2186847A1 (en) 1995-11-16
NO964735L (no) 1997-01-10
WO1995030683A1 (en) 1995-11-16
JPH09512823A (ja) 1997-12-22
FI964468A0 (fi) 1996-11-06
AU2546195A (en) 1995-11-29
PL316985A1 (en) 1997-03-03
SK146096A3 (en) 1997-07-09
FI964468A (fi) 1996-11-06
NO964735D0 (no) 1996-11-08
BR9507683A (pt) 1997-09-23

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C01 Deemed withdrawal of patent application (patent law 1993)
WD01 Invention patent application deemed withdrawn after publication