CN114768374B - Tryptophan uptake device for melatonin synthesis preparation and use method thereof - Google Patents
Tryptophan uptake device for melatonin synthesis preparation and use method thereof Download PDFInfo
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- CN114768374B CN114768374B CN202210547352.3A CN202210547352A CN114768374B CN 114768374 B CN114768374 B CN 114768374B CN 202210547352 A CN202210547352 A CN 202210547352A CN 114768374 B CN114768374 B CN 114768374B
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/02—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor with moving adsorbents
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D33/00—Filters with filtering elements which move during the filtering operation
- B01D33/06—Filters with filtering elements which move during the filtering operation with rotary cylindrical filtering surfaces, e.g. hollow drums
- B01D33/11—Filters with filtering elements which move during the filtering operation with rotary cylindrical filtering surfaces, e.g. hollow drums arranged for outward flow filtration
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D33/00—Filters with filtering elements which move during the filtering operation
- B01D33/58—Handling the filter cake in the filter for purposes other than for regenerating the filter cake remaining on the filtering element
- B01D33/60—Handling the filter cake in the filter for purposes other than for regenerating the filter cake remaining on the filtering element for washing
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
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Abstract
The invention discloses a tryptophan uptake device for melatonin synthesis preparation and a using method thereof, relates to the technical field of melatonin synthesis preparation, and aims to solve the problems that the existing tryptophan purification method is limited by an uptake purification device, a plurality of groups of different devices are required to be replaced during purification, and the steps are complicated. The flexible graphite braided sleeve is arranged between the top cover and the tank body, and the top cover is in telescopic connection with the tank body through the flexible graphite braided sleeve; the refrigeration copper coil is arranged on the outer wall of the tank body; the ceramic heating sleeve is arranged on the inner wall of the tank body; the rotary drum is arranged on the inner wall of the ceramic heating sleeve, and a plurality of filtering holes are formed in the outer wall of the rotary drum; the stirring shaft is arranged inside the rotary drum, and the upper end of the stirring shaft is in transmission connection with the output end of the asynchronous motor through a coupler; and the supporting columns are arranged on two sides of the supporting bottom plate, and the top plate is installed at the upper ends of the supporting columns.
Description
Technical Field
The invention relates to the technical field of melatonin synthesis and preparation, in particular to a tryptophan uptake device for melatonin synthesis and preparation and a using method thereof.
Background
L-tryptophan is one of eight essential amino acids of a human body, is also an important reactant for synthesizing and preparing melatonin, and needs to be taken and purified before tryptophan reaction in order to improve the purity and quality of the melatonin prepared by subsequent synthesis;
if the publication number is CN 1012450047B which is named as a tryptophan purification method, the tryptophan to be purified is dissolved in water, the filtrate after the adsorption of surface oxidation activated carbon is added, the filtrate is concentrated in vacuum at 40-65 ℃ until the original volume is 6-10%, the temperature is reduced to 3-5 ℃, the filtrate is stirred and crystallized to obtain a pure product, and the intermittent concentration and cooling crystallization mode is preferably adopted in the concentration process.
However, the existing tryptophan purification method is limited by an intake purification device, and a plurality of different devices are required to be replaced during purification, so that the steps are complicated.
Therefore, we have proposed a tryptophan uptake device for melatonin synthesis production and a method for using the same in order to solve the problems set forth above.
Disclosure of Invention
The invention aims to provide a tryptophan uptake device for melatonin synthesis preparation and a using method thereof, and aims to solve the problems that the existing tryptophan purification method provided by the background art is limited by an uptake purification device, a plurality of groups of different devices are required to be replaced during purification, and the steps are complicated.
In order to achieve the purpose, the invention provides the following technical scheme: a tryptophan uptake device for melatonin synthesis preparation comprises a supporting base plate, wherein a purification uptake device main body is arranged above the supporting base plate, the purification uptake device main body comprises a top cover, a tank body and three supporting legs, the supporting legs are arranged below the tank body, a discharge pipe is arranged at the middle position of the lower end of the tank body, a motor base is arranged at the middle position of the upper end of the top cover, an asynchronous motor is arranged in the motor base, a feed hopper is arranged on one side of the motor base, the lower end of the feed hopper extends into the tank body and is provided with a flow guide pipe, electric control valves are arranged at the connecting position of the feed hopper and the top cover and the connecting position of the discharge pipe and the tank body, a temperature and humidity sensor is arranged on the other side of the motor base and penetrates through and extends into the tank body, and a vacuum pumping joint is arranged at the front end of the motor base;
further comprising:
the flexible graphite braided sleeve is arranged between the top cover and the tank body, and the top cover is in telescopic connection with the tank body through the flexible graphite braided sleeve;
the refrigeration copper coil is arranged on the outer wall of the tank body;
the ceramic heating sleeve is arranged on the inner wall of the tank body;
the rotary drum is arranged on the inner wall of the ceramic heating sleeve, and a plurality of filtering holes are formed in the outer wall of the rotary drum;
the stirring shaft is arranged inside the rotary drum, and the upper end of the stirring shaft is in transmission connection with the output end of the asynchronous motor through a coupler;
the pillar, it sets up supporting baseplate's both sides, the roof is installed to the upper end of pillar, hydraulic telescoping rod is installed to the intermediate position department of roof upper end, and hydraulic telescoping rod's output runs through and extends to the lower extreme of roof, and with the motor cabinet transmission is connected.
Preferably, one end of the refrigeration copper coil pipe is provided with a water return joint, and the other end of the refrigeration copper coil pipe is provided with a water inlet joint.
Preferably, the periphery of top cap upper surface is provided with first electro-magnet, and first electro-magnet is provided with four, be provided with first electromagnetic adsorption piece around the ceramic heating cover up end, and first electromagnetic adsorption piece is provided with four, the both sides of ceramic heating cover up end all are provided with the electrode slice, the internally mounted of ceramic heating cover has electric heating coil.
Preferably, the inner sides of the four first electromagnets are provided with second electromagnets, the periphery of the upper surface of the rotary drum is provided with second electromagnetic adsorption sheets, and the number of the second electromagnetic adsorption sheets is four.
Preferably, the lower extreme of rotary drum is provided with the rotational positioning platform, the third electro-magnet is all installed to the both sides of rotational positioning platform, and the rotational positioning platform passes through the third electro-magnet and is connected with the bottom surface magnetic force absorption of rotary drum, the below of rotational positioning platform is provided with the power platform, the internally mounted of power platform has brushless motor, and brushless motor's output and rotational positioning platform, be provided with the ball between power platform and the rotational positioning platform, and the ball is provided with a plurality ofly, the outer wall of power platform passes through support and jar internal wall connection, be provided with the runner between power platform and the jar internal wall.
Preferably, a first activated carbon adsorption rod is installed on the outer wall of the lower end of the stirring shaft, a second activated carbon adsorption rod is arranged at the upper end of the first activated carbon adsorption rod, and one end of the second activated carbon adsorption rod is fixedly connected with the stirring shaft.
Preferably, the outer wall of the first activated carbon adsorption rod is provided with a stirring blade, and the outer wall of the second activated carbon adsorption rod is provided with a scraping blade.
Preferably, temperature and humidity sensor's one side pure water pipe joint, the lower extreme of pure water pipe joint extends to the inside of the jar body, and installs the pure water shower, first nozzle is installed to the one end of pure water shower, install the second nozzle on the outer wall of pure water shower lower extreme, and the second nozzle is provided with threely.
Preferably, the joint of the tank body and the flexible graphite weaving sleeve is provided with a pressing ring, and the pressing ring is in threaded connection with the tank body through a plurality of fastening screws.
Preferably, the method for using the tryptophan uptake device for melatonin synthesis preparation comprises the following steps:
the method comprises the following steps: firstly, respectively connecting a vacuumizing joint and a pure water pipe joint on the device with a vacuumizing pipeline and a pure water pumping pipeline to finish preparation work;
step two: after the preparation is finished, pouring 1-1.5 wt% tryptophan water solution into the device from a feed hopper, starting an asynchronous motor, driving a stirring shaft in the device to rotate by the output end of the asynchronous motor, and driving a top cover and the stirring shaft to move up and down once by a hydraulic telescopic rod in the process so that two groups of first activated carbon adsorption rods and second activated carbon adsorption rods at the lower end of the stirring shaft can fully adsorb impurities;
step three: after the impurity removal is finished, starting an electric heating coil in the ceramic heating sleeve, enabling the interior of the device to be in a vacuum state through a vacuumizing pipeline, and concentrating the solution to 6-10% of the original volume in vacuum at 40-65 ℃;
step four: after the concentration is finished, stopping heating continuously, introducing cooling water into a refrigeration copper coil outside the device, reducing the temperature to 3-5 ℃, simultaneously driving the stirring shaft to rotate again by the output end of the asynchronous motor, and stirring the concentrated solution by using the stirring blades on the outer wall of the first activated carbon adsorption rod to crystallize;
step five: after crystallization is finished, the first electromagnet on the top cover drives the top surface of the ceramic heating sleeve to be adsorbed, meanwhile, the hydraulic telescopic rod contracts, so that the top cover drives the ceramic heating sleeve to move upwards, the brushless motor drives the rotary positioning table and the rotary drum adsorbed by the third electromagnet to rotate at a high speed after crystallization is finished, water and impurities in the crystals are discharged along the filter holes in the rotary drum by utilizing centrifugal force, and the impurities and the water thrown out of the filter holes reach the discharge pipe along the flow channel to be discharged;
step six: the hydraulic telescopic rod stretches out again to drive the top cover and the ceramic heating sleeve to move downwards to a position close to the bottom surface of the tank body, filtering holes at the bottom of the rotary drum are reserved, pure water is pumped into a pure water spray pipe through a pure water pumping pipeline, crystals on the inner wall and the edge of the rotary drum are sprayed and flushed by the first nozzle and the second nozzle, and meanwhile, the rotary drum continues to rotate to continuously throw the pure water out of the filtering holes;
step seven: after washing, the hydraulic telescopic rod is completely stretched out, the ceramic heating sleeve is closed with the bottom of the tank body, and an electric heating coil in the ceramic heating sleeve is started to dry crystals at 30-45 ℃ in a vacuum environment to obtain a finished product;
step eight: after the drying is finished, the asynchronous motor drives the stirring shaft to rotate for a circle, the scraping blade on the outer wall of the second activated carbon adsorption rod is used for scraping crystals on the wall of the rotary drum, then the first electromagnet and the second electromagnet are driven simultaneously to adsorb the ceramic heating sleeve and the rotary drum, meanwhile, the third electromagnet is stopped to separate the rotary drum from the rotary positioning table, the top cover is contracted by the hydraulic telescopic rod to drive the rotary drum and the ceramic heating sleeve to move upwards simultaneously, the finished product is thrown out from the periphery under the rotating action of the rotary positioning table, and the finished product falls into the flow channel to finish discharging the material
Compared with the prior art, the invention has the beneficial effects that:
1. according to the invention, the stirring shaft and the top cover are positioned, the effect of up-and-down telescopic movement along the tank can be realized through the hydraulic telescopic rod, meanwhile, two groups of activated carbon adsorption rods are arranged on two sides of the lower end of the stirring shaft, in the step of intake and purification, 1-1.5% tryptophan water solution by weight concentration is poured into the device from the feed hopper, the asynchronous motor is started, the stirring shaft in the device is driven to rotate by the output end of the asynchronous motor, in the process, the top cover and the stirring shaft are driven to move up and down once by the hydraulic telescopic rod, so that the two groups of activated carbon adsorption rods at the lower end of the stirring shaft are in uniform contact with the solution and fully adsorb impurities.
2. The ceramic heating sleeve, the rotary drum and the pure water spray pipe are arranged in the purification and intake device, when the device needs to be heated, the ceramic heating sleeve is covered outside the rotary drum to block the filter holes on the outer wall of the rotary drum, so that materials can be heated in the inner cavity of the rotary drum; when the material needs to be centrifugally filtered, a first electromagnet on the top cover can be driven to adsorb the top surface of the ceramic heating sleeve, and meanwhile, a hydraulic telescopic rod on the top of the device contracts to enable the top cover to drive the ceramic heating sleeve to move upwards to expose the filter holes in the outer wall of the rotary drum, and then the brushless motor drives the rotary positioning table and the rotary drum to rotate at a high speed, so that the centrifugal separation of the material can be realized, and moisture and impurities can be discharged along the filter holes in the rotary drum; when the materials need to be washed, the hydraulic telescopic rod is driven to stretch out again to drive the top cover and the ceramic heating sleeve to move downwards to a position close to the bottom surface of the tank body, only filtration holes at the bottom of the rotary drum are reserved, pure water is pumped into the pure water spray pipe through the pure water pumping pipeline, and the materials on the inner wall and the edge of the rotary drum are sprayed and flushed by the nozzles.
Drawings
FIG. 1 is a schematic view of the overall structure of the present invention;
FIG. 2 is a schematic structural view of the hydraulic telescopic rod according to the present invention in a contracted state;
FIG. 3 is a schematic diagram of the internal structure of the purification intake device body according to the present invention;
FIG. 4 is a schematic view of a partial planer structure of a ceramic heating jacket according to the present invention;
FIG. 5 is a schematic view of a drum structure according to the present invention;
FIG. 6 is an enlarged view of the structure at A of the present invention;
FIG. 7 is an enlarged structural view of the structure at B of the present invention;
in the figure: 1. a support base plate; 2. a purification intake device body; 3. refrigerating a copper coil; 4. a water return joint; 5. a water inlet joint; 6. a flexible graphite braided sleeve; 7. a top cover; 8. pressing a ring; 9. a motor base; 10. an asynchronous motor; 11. a feed hopper; 12. a temperature and humidity sensor; 13. a pure water pipe joint; 14. a first electromagnet; 15. a second electromagnet; 16. a discharge pipe; 17. an electrically controlled valve; 18. supporting legs; 19. a pillar; 20. a top plate; 21. a hydraulic telescopic rod; 22. a flow guide pipe; 23. a tank body; 24. a ceramic heating jacket; 241. an electric heating coil; 242. a first electromagnetic attraction sheet; 243. an electrode sheet; 25. rotating the drum; 251. a second electromagnetic attraction sheet; 26. a power stage; 27. a brushless motor; 28. a flow channel; 29. rotating the positioning table; 30. filtering holes; 31. a pure water spray pipe; 32. a first nozzle; 33. a second nozzle; 34. a coupling; 35. a stirring shaft; 36. a first activated carbon adsorption rod; 37. a second activated carbon adsorption rod; 38. stirring blades; 39. scraping a blade; 40. fastening screws; 41. a support; 42. a ball bearing; 43. a third electromagnet; 44. and (6) vacuumizing the joint.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Referring to fig. 1-7, an embodiment of the present invention is shown: a tryptophan uptake device for melatonin synthesis preparation comprises a supporting base plate 1, a purification uptake device main body 2 is arranged above the supporting base plate 1, the purification uptake device main body 2 comprises a top cover 7, a tank body 23 and supporting legs 18, the supporting legs 18 are arranged below the tank body 23, three supporting legs 18 are arranged, a discharge pipe 16 is arranged at the middle position of the lower end of the tank body 23, a motor base 9 is arranged at the middle position of the upper end of the top cover 7, an asynchronous motor 10 is arranged inside the motor base 9, a feed hopper 11 is arranged on one side of the motor base 9, the lower end of the feed hopper 11 extends into the tank body 23, a guide pipe 22 is arranged, an electric control valve 17 is arranged at the joint of the feed hopper 11 and the top cover 7 and the joint of the discharge pipe 16 and the tank body 23, a temperature and humidity sensor 12 is arranged on the other side of the motor base 9, the temperature and humidity sensor 12 penetrates and extends into the tank body 23, and a vacuum pumping joint 44 is arranged at the front end of the motor base 9;
further comprising:
the flexible graphite braided sleeve 6 is arranged between the top cover 7 and the tank body 23, and the top cover 7 is in telescopic connection with the tank body 23 through the flexible graphite braided sleeve 6;
a refrigeration copper coil 3 provided on the outer wall of the tank 23;
a ceramic heating jacket 24 provided on an inner wall of the can 23;
a rotary drum 25 arranged on the inner wall of the ceramic heating jacket 24, wherein the outer wall of the rotary drum 25 is provided with a plurality of filtering holes 30;
the stirring shaft 35 is arranged inside the rotary drum 25, and the upper end of the stirring shaft 35 is in transmission connection with the output end of the asynchronous motor 10 through a coupler 34;
the supporting columns 19 are arranged on two sides of the supporting base plate 1, the top plate 20 is installed at the upper ends of the supporting columns 19, the hydraulic telescopic rods 21 are installed at the middle positions of the upper ends of the top plate 20, and the output ends of the hydraulic telescopic rods 21 penetrate through and extend to the lower end of the top plate 20 and are in transmission connection with the motor base 9.
Referring to fig. 1, one end of the refrigeration copper coil 3 is provided with a water return joint 4, the other end of the refrigeration copper coil 3 is provided with a water inlet joint 5, and the refrigeration copper coil 3 is used for guiding cooling water, so that the internal temperature of the device can be conveniently reduced.
Referring to fig. 1 and 4, the periphery of the upper surface of the top cover 7 is provided with four first electromagnets 14, four first electromagnetic attraction pieces 242 are arranged around the upper end surface of the ceramic heating jacket 24, four first electromagnetic attraction pieces 242 are arranged on the first electromagnetic attraction pieces 242, electrode pieces 243 are arranged on both sides of the upper end surface of the ceramic heating jacket 24, an electric heating coil 241 is installed inside the ceramic heating jacket 24, the device realizes heating by the electric heating coil 241 inside the ceramic heating jacket 24, when centrifugal filtration is needed, the ceramic heating jacket 24 is attracted by the first electromagnet 14 on the top cover and is driven by the hydraulic telescopic rod 21 to move upwards, so that the filtration holes 30 on the outer wall of the rotary drum 25 are communicated with the flow channel 28.
Referring to fig. 1 and 5, the inner sides of the four first electromagnets 14 are provided with the second electromagnets 15, the periphery of the upper surface of the rotating drum 25 is provided with the second electromagnetic attraction pieces 251, and the number of the second electromagnetic attraction pieces 251 is four, after the purification is completed, the rotating drum 25 can be attracted by the second electromagnets 15, and the hydraulic telescopic rod 21 drives the rotating drum to lift, so that the crystallization and discharge are facilitated.
Referring to fig. 3, a rotary positioning table 29 is disposed at a lower end of the rotary drum 25, third electromagnets 43 are disposed on two sides of the rotary positioning table 29, the rotary positioning table 29 is magnetically connected to a bottom surface of the rotary drum 25 through the third electromagnets 43, a power table 26 is disposed below the rotary positioning table 29, a brushless motor 27 is disposed inside the power table 26, an output end of the brushless motor 27 is connected to the rotary positioning table 29, a plurality of balls 42 are disposed between the power table 26 and the rotary positioning table 29, an outer wall of the power table 26 is connected to an inner wall of the tank 23 through a bracket 41, a flow channel 28 is disposed between the power table 26 and the inner wall of the tank 23, the brushless motor 27 can drive the rotary positioning table 29 to drive the rotary drum 25, which is attracted by the third electromagnets 43, to rotate, so as to achieve centrifugal filtration of materials, and when the rotary drum 25 needs to be separated, the third electromagnets 43 can stop magnetic attraction.
Referring to fig. 3 and 7, a first activated carbon adsorption rod 36 is installed on an outer wall of a lower end of the stirring shaft 35, a second activated carbon adsorption rod 37 is installed at an upper end of the first activated carbon adsorption rod 36, and one end of the second activated carbon adsorption rod 37 is fixedly connected to the stirring shaft 35, so that the first activated carbon adsorption rod 36 and the second activated carbon adsorption rod 37 can directly adsorb solution impurities, thereby achieving a purification effect.
Referring to fig. 3 and 7, the outer wall of the first activated carbon adsorption rod 36 is provided with a stirring blade 38, the outer wall of the second activated carbon adsorption rod 37 is provided with a scraping blade 39, the stirring blade 38 can improve the stirring effect of the stirring shaft 35, and the scraping blade 39 can scrape off the material on the wall of the rotating drum 25.
Referring to fig. 1 and 3, a pure water pipe joint 13 is disposed on one side of the temperature and humidity sensor 12, a lower end of the pure water pipe joint 13 extends into the tank 23, and is provided with a pure water spray pipe 31, a first nozzle 32 is disposed at one end of the pure water spray pipe 31, a second nozzle 33 is disposed on an outer wall of a lower end of the pure water spray pipe 31, and three second nozzles 33 are disposed, and the pure water spray pipe 31 is used for introducing pure water washing materials.
Referring to fig. 1 and 6, a pressing ring 8 is arranged at the joint of the tank 23 and the flexible graphite braided sleeve 6, the pressing ring 8 is in threaded connection with the tank 23 through a plurality of fastening screws 40, when the flexible graphite braided sleeve 6 needs to be separated, the fastening screws 40 on the pressing ring 8 are dismounted, and the pressing ring 8 is dismounted, so that the internal stirring element can be conveniently and regularly overhauled and maintained.
Referring to fig. 1-7, a method for using a tryptophan uptake device for melatonin synthesis preparation comprises the following steps:
the method comprises the following steps: firstly, respectively connecting a vacuumizing joint 44 and a pure water pipe joint 13 on the device with a vacuumizing pipeline and a pure water pumping pipeline to finish preparation work;
step two: after the preparation is finished, pouring 1-1.5 wt% tryptophan water solution into the device from a feed hopper 11, starting an asynchronous motor 10, driving a stirring shaft 35 in the device to rotate by an output end of the asynchronous motor 10, and in the process, driving a top cover 7 and the stirring shaft 35 to move up and down once by a hydraulic telescopic rod 21 so that two groups of first activated carbon adsorption rods 36 and second activated carbon adsorption rods 37 at the lower end of the stirring shaft 35 fully adsorb impurities;
step three: after the impurity removal is finished, starting an electric heating coil 241 in the ceramic heating sleeve 24, enabling the device to be in a vacuum state through a vacuum-pumping pipeline, and concentrating the solution in vacuum at 40-65 ℃ until the original volume is 6-10%;
step four: after the concentration is finished, stopping heating continuously, introducing cooling water into a refrigeration copper coil pipe 3 outside the device, reducing the temperature to 3-5 ℃, simultaneously driving the stirring shaft 35 to rotate again by the output end of the asynchronous motor 10, and stirring the concentrated solution by using the stirring blade 38 on the outer wall of the first activated carbon adsorption rod 36 to crystallize the concentrated solution;
step five: after crystallization is finished, the first electromagnet 14 on the top cover 7 is driven to adsorb the top surface of the ceramic heating sleeve 24, meanwhile, the hydraulic telescopic rod 21 contracts, so that the top cover 7 drives the ceramic heating sleeve 24 to move upwards, the brushless motor 27 drives the rotary positioning table 29 and the rotary drum 25 adsorbed by the third electromagnet 43 to rotate at high speed after crystallization is finished, moisture and impurities in the crystallization are discharged along the filter holes 30 on the rotary drum 25 by using centrifugal force, and the impurities and the moisture thrown out of the filter holes 30 reach the discharge pipe 16 along the flow channel 28 to be discharged;
step six: the hydraulic telescopic rod 21 extends out again to drive the top cover 7 and the ceramic heating sleeve 24 to move downwards to a position close to the bottom surface of the tank body 23, a filtering hole 30 in the bottom of the rotary drum 25 is reserved, pure water is pumped into a pure water spraying pipe 31 through a pure water pumping pipeline, crystals on the inner wall and the edge of the rotary drum 25 are sprayed and flushed by a first nozzle 32 and a second nozzle 33, meanwhile, the rotary drum 25 continues to rotate, and pure water is continuously thrown out of the filtering hole 30;
step seven: after washing, the hydraulic telescopic rod 21 is completely extended out, so that the ceramic heating sleeve 24 and the bottom of the tank body 23 are closed, an electric heating coil 241 in the ceramic heating sleeve 24 is started, and crystals are dried in a vacuum environment at the temperature of 30-45 ℃ to obtain a finished product;
step eight: after drying, the asynchronous motor 10 drives the stirring shaft 35 to rotate for a circle, the scraping blade 39 on the outer wall of the second activated carbon adsorption rod 37 is used for scraping crystals on the wall of the rotary drum 25, then the first electromagnet 14 and the second electromagnet 15 are driven simultaneously to adsorb the ceramic heating sleeve 24 and the rotary drum 25, meanwhile, the third electromagnet 43 is stopped, the rotary drum 25 is separated from the rotary positioning table 29, the hydraulic telescopic rod 21 contracts the top cover 7 to drive the rotary drum 25 and the ceramic heating sleeve 24 to move upwards simultaneously, finished products are thrown out from the periphery under the rotation action of the rotary positioning table 29, and the finished products fall into the flow channel 28 to finish discharging.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Claims (3)
1. A tryptophan uptake device for melatonin synthesis preparation comprises a supporting base plate (1), wherein a purification uptake device main body (2) is arranged above the supporting base plate (1), the purification uptake device main body (2) comprises a top cover (7), a tank body (23) and supporting legs (18), the supporting legs (18) are arranged below the tank body (23), three supporting legs (18) are arranged, a discharge pipe (16) is arranged at the middle position of the lower end of the tank body (23), a motor base (9) is arranged at the middle position of the upper end of the top cover (7), an asynchronous motor (10) is arranged inside the motor base (9), a feed hopper (11) is arranged on one side of the motor base (9), the lower end of the feed hopper (11) extends into the tank body (23) and is provided with a guide pipe (22), an electric control valve (17) is arranged at the joint of the feed hopper (11) and the top cover (7) and the joint of the discharge pipe (16) and the tank body (23), an electric control valve (17) is arranged at the other side of the motor base (9), a temperature and humidity sensor (12) penetrates through the temperature and humidity sensor (12) and extends into the tank body (23), and a vacuum extraction joint (44) is arranged at the front end of the motor base (44) arranged at the motor base (9);
the method is characterized in that: further comprising:
the flexible graphite braided sleeve (6) is arranged between the top cover (7) and the tank body (23), and the top cover (7) is in telescopic connection with the tank body (23) through the flexible graphite braided sleeve (6);
the refrigeration copper coil (3) is arranged on the outer wall of the tank body (23);
a ceramic heating jacket (24) disposed on an inner wall of the tank (23);
the rotary drum (25) is arranged on the inner wall of the ceramic heating sleeve (24), and a plurality of filtering holes (30) are formed in the outer wall of the rotary drum (25);
the stirring shaft (35) is arranged inside the rotary drum (25), and the upper end of the stirring shaft (35) is in transmission connection with the output end of the asynchronous motor (10) through a coupler (34);
the supporting columns (19) are arranged on two sides of the supporting base plate (1), a top plate (20) is mounted at the upper end of each supporting column (19), a hydraulic telescopic rod (21) is mounted in the middle of the upper end of each top plate (20), and the output end of each hydraulic telescopic rod (21) penetrates through and extends to the lower end of each top plate (20) and is in transmission connection with the motor base (9);
the periphery of the upper surface of the top cover (7) is provided with four first electromagnets (14), the periphery of the upper end surface of the ceramic heating sleeve (24) is provided with four first electromagnetic adsorption sheets (242), the number of the first electromagnetic adsorption sheets (242) is four, the two sides of the upper end surface of the ceramic heating sleeve (24) are provided with electrode sheets (243), and an electric heating coil (241) is arranged in the ceramic heating sleeve (24);
a rotary positioning table (29) is arranged at the lower end of the rotary drum (25), third electromagnets (43) are mounted on two sides of the rotary positioning table (29), and the rotary positioning table (29) is in magnetic adsorption connection with the bottom surface of the rotary drum (25) through the third electromagnets (43);
a first activated carbon adsorption rod (36) is mounted on the outer wall of the lower end of the stirring shaft (35), a second activated carbon adsorption rod (37) is arranged at the upper end of the first activated carbon adsorption rod (36), and one end of the second activated carbon adsorption rod (37) is fixedly connected with the stirring shaft (35);
the outer wall of the first activated carbon adsorption rod (36) is provided with a stirring blade (38), and the outer wall of the second activated carbon adsorption rod (37) is provided with a scraping blade (39);
one side of the temperature and humidity sensor (12) is provided with a pure water pipe joint (13), the lower end of the pure water pipe joint (13) extends into the tank body (23) and is provided with a pure water spray pipe (31), one end of the pure water spray pipe (31) is provided with a first nozzle (32), the outer wall of the lower end of the pure water spray pipe (31) is provided with three second nozzles (33);
second electromagnets (15) are arranged on the inner sides of the four first electromagnets (14), second electromagnetic adsorption sheets (251) are arranged on the periphery of the upper surface of the rotary drum (25), and four second electromagnetic adsorption sheets (251) are arranged;
a power table (26) is arranged below the rotary positioning table (29), a brushless motor (27) is arranged in the power table (26), the output end of the brushless motor (27) is connected with the rotary positioning table (29), a plurality of balls (42) are arranged between the power table (26) and the rotary positioning table (29), the outer wall of the power table (26) is connected with the inner wall of the tank body (23) through a support (41), and a flow channel (28) is arranged between the power table (26) and the inner wall of the tank body (23);
the use method of the tryptophan uptake device for melatonin synthesis preparation comprises the following steps:
the method comprises the following steps: firstly, a vacuumizing joint (44) and a pure water pipe joint (13) on the device are respectively connected with a vacuumizing pipeline and a pure water pumping pipeline to finish preparation work;
step two: after the preparation is finished, pouring 1-1.5 wt% tryptophan water solution into the device from a feed hopper (11), starting an asynchronous motor (10), driving a stirring shaft (35) in the device to rotate by the output end of the asynchronous motor (10), and in the process, driving a top cover (7) and the stirring shaft (35) to move up and down once by a hydraulic telescopic rod (21) so that two groups of first activated carbon adsorption rods (36) and second activated carbon adsorption rods (37) at the lower end of the stirring shaft (35) fully adsorb impurities;
step three: after the impurity removal is finished, starting an electric heating coil (241) in a ceramic heating sleeve (24), enabling the interior of the device to be in a vacuum state through a vacuumizing pipeline, and concentrating the solution to 6-10% of the original volume in vacuum at the temperature of 40-65 ℃;
step four: after the concentration is finished, stopping heating continuously, introducing cooling water into a refrigeration copper coil (3) outside the device, reducing the temperature to 3-5 ℃, simultaneously driving the stirring shaft (35) to rotate again by the output end of the asynchronous motor (10), and stirring the concentrated solution by using the stirring blade (38) on the outer wall of the first activated carbon adsorption rod (36) to crystallize;
step five: after crystallization is finished, a first electromagnet (14) on the top cover (7) is driven to adsorb the top surface of the ceramic heating sleeve (24), meanwhile, the hydraulic telescopic rod (21) is contracted to enable the top cover (7) to drive the ceramic heating sleeve (24) to move upwards, after crystallization is finished, the brushless motor (27) is driven to drive the rotary positioning table (29) and the rotary drum (25) adsorbed by the third electromagnet (43) to rotate at high speed, moisture and impurities in the crystallization are discharged along the filtering holes (30) on the rotary drum (25) by utilizing centrifugal force, and the impurities and the moisture thrown out of the filtering holes (30) reach the discharge pipe (16) along the flow channel (28) to be discharged;
step six: the hydraulic telescopic rod (21) stretches out again to drive the top cover (7) and the ceramic heating sleeve (24) to move downwards to a position close to the bottom surface of the tank body (23), filtering holes (30) at the bottom of the rotary drum (25) are reserved, pure water is pumped into a pure water spraying pipe (31) through a pure water pumping pipeline, crystals on the inner wall and the edge of the rotary drum (25) are sprayed and flushed through the first nozzle (32) and the second nozzle (33), meanwhile, the rotary drum (25) continues to rotate, and pure water is continuously thrown out of the filtering holes (30);
step seven: after washing, the hydraulic telescopic rod (21) is completely extended out, the ceramic heating sleeve (24) and the bottom of the tank body (23) are closed, an electric heating coil (241) in the ceramic heating sleeve (24) is started, and crystals are dried in a vacuum environment at the temperature of 30-45 ℃ to obtain a finished product;
step eight: after drying is finished, an asynchronous motor (10) drives a stirring shaft (35) to rotate for a circle, scrapes crystals on the wall of a rotary drum (25) by using a scraping blade (39) on the outer wall of a second activated carbon adsorption rod (37), then a first electromagnet (14) and a second electromagnet (15) are driven simultaneously to adsorb a ceramic heating sleeve (24) and the rotary drum (25), and a third electromagnet (43) stops to separate the rotary drum (25) from a rotary positioning table (29), a hydraulic telescopic rod (21) shrinks a top cover (7) to drive the rotary drum (25) and the ceramic heating sleeve (24) to move upwards simultaneously, finished products are thrown out from the periphery under the rotating action of the rotary positioning table (29), and the finished products fall into a flow channel (28) to finish discharging.
2. The tryptophan uptake device for melatonin synthesis preparation according to claim 1, wherein: one end of the refrigeration copper coil pipe (3) is provided with a water return joint (4), and the other end of the refrigeration copper coil pipe (3) is provided with a water inlet joint (5).
3. The tryptophan uptake device for melatonin synthesis preparation according to claim 2, wherein: the connection of the tank body (23) and the flexible graphite weaving sleeve (6) is provided with a pressing ring (8), and the pressing ring (8) is in threaded connection with the tank body (23) through a plurality of fastening screws (40).
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