CN114768078A - Tattoo electrode and preparation method and system thereof - Google Patents
Tattoo electrode and preparation method and system thereof Download PDFInfo
- Publication number
- CN114768078A CN114768078A CN202210197423.1A CN202210197423A CN114768078A CN 114768078 A CN114768078 A CN 114768078A CN 202210197423 A CN202210197423 A CN 202210197423A CN 114768078 A CN114768078 A CN 114768078A
- Authority
- CN
- China
- Prior art keywords
- electrode
- layer
- tattoo
- conductive
- magnetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title abstract description 16
- 239000010410 layer Substances 0.000 claims abstract description 136
- 229920001940 conductive polymer Polymers 0.000 claims abstract description 40
- 238000012546 transfer Methods 0.000 claims abstract description 30
- 210000004556 brain Anatomy 0.000 claims abstract description 22
- 238000007641 inkjet printing Methods 0.000 claims abstract description 22
- 239000000463 material Substances 0.000 claims abstract description 21
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims abstract description 19
- 239000002042 Silver nanowire Substances 0.000 claims abstract description 18
- 238000010521 absorption reaction Methods 0.000 claims abstract description 17
- 239000012790 adhesive layer Substances 0.000 claims abstract description 17
- 239000004020 conductor Substances 0.000 claims abstract description 15
- 229920000642 polymer Polymers 0.000 claims abstract description 13
- 229920001609 Poly(3,4-ethylenedioxythiophene) Polymers 0.000 claims abstract description 10
- 210000003491 skin Anatomy 0.000 claims description 27
- 239000002122 magnetic nanoparticle Substances 0.000 claims description 13
- 239000000758 substrate Substances 0.000 claims description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 208000005156 Dehydration Diseases 0.000 claims description 8
- 230000018044 dehydration Effects 0.000 claims description 8
- 238000006297 dehydration reaction Methods 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 8
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 7
- 210000004207 dermis Anatomy 0.000 claims description 7
- 239000011248 coating agent Substances 0.000 claims description 6
- 238000000576 coating method Methods 0.000 claims description 6
- 239000002322 conducting polymer Substances 0.000 claims description 6
- 239000001856 Ethyl cellulose Substances 0.000 claims description 5
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 claims description 5
- 229920001249 ethyl cellulose Polymers 0.000 claims description 5
- 235000019325 ethyl cellulose Nutrition 0.000 claims description 5
- 238000000151 deposition Methods 0.000 claims description 4
- 230000008054 signal transmission Effects 0.000 abstract description 10
- 210000004243 sweat Anatomy 0.000 abstract description 6
- 239000002861 polymer material Substances 0.000 abstract description 5
- 230000029058 respiratory gaseous exchange Effects 0.000 abstract description 5
- 238000002834 transmittance Methods 0.000 abstract description 5
- 230000035699 permeability Effects 0.000 abstract description 2
- 238000004519 manufacturing process Methods 0.000 description 7
- 229920000144 PEDOT:PSS Polymers 0.000 description 5
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 238000004090 dissolution Methods 0.000 description 4
- 229910052751 metal Inorganic materials 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 230000036548 skin texture Effects 0.000 description 4
- 230000005389 magnetism Effects 0.000 description 3
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 238000005411 Van der Waals force Methods 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 210000002615 epidermis Anatomy 0.000 description 2
- 229910021389 graphene Inorganic materials 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000001259 photo etching Methods 0.000 description 2
- 238000007639 printing Methods 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 230000003014 reinforcing effect Effects 0.000 description 2
- YNQLUTRBYVCPMQ-UHFFFAOYSA-N Ethylbenzene Chemical compound CCC1=CC=CC=C1 YNQLUTRBYVCPMQ-UHFFFAOYSA-N 0.000 description 1
- 229910052689 Holmium Inorganic materials 0.000 description 1
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- WYTGDNHDOZPMIW-RCBQFDQVSA-N alstonine Natural products C1=CC2=C3C=CC=CC3=NC2=C2N1C[C@H]1[C@H](C)OC=C(C(=O)OC)[C@H]1C2 WYTGDNHDOZPMIW-RCBQFDQVSA-N 0.000 description 1
- 238000005229 chemical vapour deposition Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- KJZYNXUDTRRSPN-UHFFFAOYSA-N holmium atom Chemical compound [Ho] KJZYNXUDTRRSPN-UHFFFAOYSA-N 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
- 229910001172 neodymium magnet Inorganic materials 0.000 description 1
- 231100000065 noncytotoxic Toxicity 0.000 description 1
- 230000002020 noncytotoxic effect Effects 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 229960002796 polystyrene sulfonate Drugs 0.000 description 1
- 239000011970 polystyrene sulfonate Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 229910052594 sapphire Inorganic materials 0.000 description 1
- 239000010980 sapphire Substances 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000003746 surface roughness Effects 0.000 description 1
- 238000010023 transfer printing Methods 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0076—Tattooing apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Virology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Decoration By Transfer Pictures (AREA)
Abstract
The invention discloses a tattoo electrode and a preparation method and a system thereof. The tattoo electrode comprises a conductive layer and transfer tattoo paper; the conductive layer comprises a conductive body wrapped by a conductive polymer, wherein the conductive polymer is PEDOT (PSS material), and the conductive body is a silver nanowire; the transfer tattoo paper comprises an adhesive layer, a dissolving layer and a supporting layer; the conductive layer is used to form an all-polymer electrode by ink-jet printing an electrical conductor onto the adhesive layer and the support layer. According to the tattoo electrode and the preparation method and system thereof, the conductive layer, the transfer tattoo paper and the magnetic absorption layer are arranged, and the materials corresponding to all the layers are reasonably selected, so that the light transmittance and the air permeability of the tattoo electrode can be enhanced by using the silver nanowire material in a network shape, the influence of sweat on brain signal transmission is reduced while the skin respiration is not hindered, and the tattoo electrode has washability by using the non-hydrophilicity of the conductive polymer material, and can stably record the brain signals for a long time.
Description
Technical Field
The invention relates to the technical field of bioelectrode, in particular to a tattoo electrode and a preparation method and a system thereof.
Background
The tattoo electrode is a flexible, stretchable and ultrathin electronic sensing device, can be attached to the skin of a human body to record various human electrophysiological signals with high signal-to-noise ratio, and has great application prospect in the fields of brain-computer interfaces, daily health monitoring and intelligent medical treatment. 2017, a graphene-based tattoo electrode in the shape of filamentous serpentine was developed in the united states, which has a high stretchability of 40%, an optical transparency of 85%, and a mesh structure that can provide good air permeability. However, since the electrode is produced by chemical vapor deposition, the obtained graphene is easily damaged, it is difficult to obtain a desired tattoo pattern, and the durability is low. France and Italy in 2018 cooperate to develop a tattooing electrode for brain signal measurement, a conductive polymer is printed on transfer tattooing paper in an ink-jet printing mode, and the conductive polymer and the tattooing paper are optimized to record brain signals with high quality and high signal-to-noise ratio, but the cost is high, and the process is complex and time-consuming. In addition, the current tattooing electrodes often have the disadvantages of poor adhesion, complicated connection of electrode connectors, and the like.
Disclosure of Invention
The invention provides a tattoo electrode and a preparation method and a system thereof, aiming at overcoming the defects of poor adhesiveness of the tattoo electrode, complex connection and the like in the prior art.
The invention solves the technical problems through the following technical scheme:
the invention provides a tattoo electrode, which comprises a conductive layer and transfer tattoo paper;
the conducting layer comprises a conductor wrapped by a conducting polymer, wherein the conducting polymer is PEDOT (PSS (poly 3, 4-ethyl benzene dioxythiophene and polystyrene sulfonate)) material, and the conductor is silver nanowire; the transfer tattoo paper comprises an adhesive layer, a dissolving layer and a supporting layer; the conductive layer is used to form an all-polymer electrode by ink-jet printing the electrical conductor onto the adhesive layer and the support layer.
Preferably, one side of the adhesive layer is the supporting layer; the other side of the adhesive layer is used for being attached to human skin.
Preferably, the dissolution layer comprises a water-soluble polyethylene oxide substrate; the support layer comprises an ethyl cellulose layer.
Preferably, the magnetic absorption layer is also included; the magnetic absorption layer comprises magnetic nanoparticles wrapped by the conductive polymer;
the magnetic layer is used for magnetically attracting the electrode connector so as to enable the electrode connector to output brain signals acquired by the tattooing electrode; wherein the electrode connector comprises a magnetic disk for magnetically attracting the magnetic attraction layer and the electrode connector.
The invention also provides a preparation method of the tattooing electrode, which is used for preparing the tattooing electrode and comprises the following steps:
ink-jet printing the conductor of the tattoo electrode on transfer tattoo paper of the tattoo electrode to generate a full polymer electrode;
and performing dissolving and dewatering treatment on the transfer tattoo paper to dissolve the dissolving layer and form the supporting layer, wherein the supporting layer is used for supporting the conductive layer of the tattoo electrode.
Preferably, the thickness of the support layer is 500nm (nanometers).
Preferably, the preparation method further comprises: coating the conductive polymer of the tattooing electrode on the magnetic nanoparticles, and dissolving the conductive polymer in water with a preset volume ratio to generate a high-concentration ink solution; the high-concentration ink solution is used for depositing on a dermis layer to form a magnetic absorption layer.
The invention also provides a preparation system of the tattooing electrode, which is used for preparing the tattooing electrode, and the preparation system comprises:
an ink jet printing module for ink jet printing the conductor of the tattoo electrode on the transfer tattoo paper of the tattoo electrode to generate a full polymer electrode;
and the dehydration treatment module is used for dissolving and dehydrating the transfer tattoo paper so as to dissolve the dissolving layer and form the supporting layer, and the supporting layer is used for supporting the conductive layer of the tattoo electrode.
Preferably, the thickness of the support layer is 500 nm.
Preferably, the preparation system further comprises a magnetic suction module, which is used for coating the conductive polymer of the tattoo electrode on the magnetic nanoparticles and dissolving the conductive polymer in water with a preset volume proportion to generate a high-concentration ink solution; the high-concentration ink solution is used for depositing on a dermis layer to form a magnetic absorption layer.
The positive progress effects of the invention are as follows: according to the tattoo electrode and the preparation method and system thereof, the conductive layer, the transfer tattoo paper and the magnetic absorption layer are arranged, and the materials corresponding to the layers are reasonably selected, so that the light transmittance and the electric conductivity of the tattoo electrode can be enhanced by utilizing the electric conductivity and the transmissivity of the silver nanowire material in the network shape, the skin respiration is not hindered, and the influence of sweat on brain signal transmission is reduced. The conductive polymer material is not hydrophilic, so that the tattooing electrode has washability and can stably record brain signals for a long time. The magnetic absorption layer enables the electrode connector to be absorbed on the tattoo electrode for signal transmission, and improves the operation convenience of the brain-computer interface. In addition, the tattooing electrode is directly attached to the skin texture of a human body, so that the induction area, the interface adhesive force and the stability can be increased to the maximum extent, the recording signal-to-noise ratio of an electroencephalogram signal is improved, and the problems of signal quality attenuation, motion artifacts and the like in the traditional electrode based on hard metal or conductive gel are solved. The tattooing electrode can stretch and bend along with the skin, so that the biocompatibility is improved.
Drawings
Fig. 1 is a schematic structural view of a tattooing electrode according to embodiment 1 of the present invention.
FIG. 2 is a schematic structural view of a transfer tattooing paper according to the tattooing electrode of example 1 of the present invention.
Fig. 3 is a flowchart of a method for manufacturing a tattooing electrode according to example 2 of the present invention.
Fig. 4 is a block diagram illustrating a system for manufacturing a tattooing electrode according to example 3 of the present invention.
Detailed Description
The invention is further illustrated by the following examples, which are not intended to limit the scope of the invention.
Example 1
Referring to fig. 1, the present embodiment specifically provides a tattooing electrode, which includes a conductive layer 101, transfer tattoo paper 102, and a magnetic attraction layer 103. The conducting layer 101 comprises a conducting body wrapped by conducting polymer, wherein the conducting polymer is PEDOT, PSS material, and the conducting body is silver nanowire; the transfer tattoo paper 102 includes an adhesive layer, a dissolving layer, and a support layer; the conductive layer 101 is used to form an all-polymer electrode by ink-jet printing an electrical conductor onto the adhesive layer and the support layer. Optionally, the magnetically attractive layer 103 comprises magnetic nanoparticles encapsulated by a conductive polymer; the magnetic attraction layer 103 is used for magnetically attracting the electrode connector so as to enable the electrode connector to output brain signals acquired by the tattoo electrode; wherein the electrode connector comprises a magnetic disk for magnetically attracting the magnetic attraction layer and the electrode connector.
For the conductive layer, silver nanowires are used as a conductive material of the conductive layer because of their high conductivity, high flexibility, and high light transmittance. However, due to the characteristics of high surface roughness, low adhesion with a flexible substrate and the like of the silver nanowire material, the conductive polymer consisting of PEDOT and PSS is coated on the silver nanowires with the net structure, the silver nanowires with the net structure can ensure the respiration and light transmittance of the skin, and the influence of sweat on the brain signal acquisition of the tattoo electrode is reduced. The conductive polymer PEDOT: PSS has the advantages of high conductivity, printability and chemical stability, and can be easily processed into a film shape using conventional techniques. The conductive polymer PEDOT, PSS, is also a non-cytotoxic material, does not pose any risk to skin host cells when attached to human skin, and therefore has good biocompatibility.
As a preferred embodiment, refer to fig. 2 showing a structure of a transfer tattoo paper, wherein one side of an adhesive layer 1 is a support layer 2; it will be appreciated that the other side of the adhesive layer 1 is intended to be attached to human skin. The dissolving layer 3 is a water-soluble polyethylene oxide substrate; the support layer 2 comprises an ethylcellulose layer. Wherein the adhesive layer 1 can be securely adhered to the skin of the human body. The dissolving layer 3 functions as a temporary soft base, and the ethyl cellulose layer remaining after dissolving functions as a support layer 2 for supporting the conductive layer of the tattoo electrode. Wherein the ethylcellulose layer is a low cost, skin-safe and easy to use material. In this way, the conductive layer on the support layer of the transfer tattoo paper is easily and stably transferred to the skin of a human body.
The magnetic absorption layer is mainly made of magnetic nanoparticles wrapped by a conductive polymer film PEDOT (polymer foot nano-particles) PSS (patterned sapphire substrate), and is mainly used for recording brain signals, and the brain signals with high signal-to-noise ratio can be stably recorded for a long time only by adsorbing an electrode connector with the magnet characteristic on a tattoo electrode. The preparation process comprises the steps of firstly coating conductive polymer PEDOT: PSS on magnetic nano particles, dissolving the magnetic nano particles in water with a certain proportion, and preparing the magnetic nano particles into a high-concentration ink solution. In the specific use process of the tattooing electrode of this embodiment, when tattooing is started, a circle of skin around the conductive layer may be disinfected and vaseline may be applied, and then the tattooing gun is used, and the tattooing needle thereof punctures the epidermis layer of the skin at a high speed and then the ink solution is brought into the skin around the conductive layer and deposited in the dermis layer under the epidermis layer, thereby forming the magnetic absorption layer. It can be understood that the signal transmission of the tattoo electrode is relayed through the electrode connector, the material of the center of the electrode connector can be silver or silver chloride to play a role of electric conduction, the periphery of the electrode connector is a magnetic disc, the material of the electrode connector can be neodymium-iron-boron magnet, the electrode connector is a permanent magnet with the magnetism second to that of the absolute zero-degree holmium magnet, and the electrode connector plays a role of magnetically attracting the magnetic layer of the tattoo electrode. When the brain signal is required to be recorded, the center of the electrode connector align to the conductive layer of the human skin, and the magnetic disk can be connected with the skin magnetic attraction layer according to the magnetic attraction effect, so that the center of the electrode connector is stably connected with the conductive layer of the skin, and the electrode connector can be used for transmitting the brain signal.
The layer is inhaled through setting up conducting layer, rendition tattoo paper and magnetism to the tattoo electrode of this embodiment to and select for use the material that each layer corresponds rationally, can utilize the electric conductivity and the transmissivity of the silver nanowire material of network shape reinforcing tattoo electrode's light transmissivity and electric conductive property, and do not hinder the influence of reduction sweat to brain signal transmission when skin is breathed. The conductive polymer material is not hydrophilic, so that the tattooing electrode has washability and can stably record brain signals for a long time. The magnetic absorption layer enables the electrode connector to be absorbed on the tattoo electrode for signal transmission, and improves the operation convenience of the brain-computer interface. In addition, the tattoo electrode is directly attached to the skin texture of a human body, so that the sensing area, the interface adhesive force and the stability can be increased to the maximum extent, the recording signal-to-noise ratio of an electroencephalogram signal is improved, and the problems of signal quality attenuation, motion artifacts and the like in the traditional electrode based on hard metal or conductive gel are solved. The tattooing electrode can stretch and bend along with the skin, so that the biocompatibility is improved.
Example 2
Referring to fig. 3, this example specifically provides a method for preparing a tattooing electrode according to example 1, which includes:
s1, ink-jet printing a conductor of a tattoo electrode on transfer tattoo paper to generate a full-polymer electrode;
and S2, dissolving and dehydrating the transfer tattoo paper to dissolve the dissolving layer and form a supporting layer, wherein the supporting layer is used for supporting the conducting layer of the tattoo electrode. Preferably, the thickness of the support layer is 500 nm.
Step S1, inkjet printing the silver nanowires wrapped in the conductive polymer film PEDOT: PSS on the water-soluble polyethylene oxide substrate (i.e., the dissolved layer) of the adhesive layer and the support layer of the transfer tattoo paper to obtain the all-polymer electrode. Specifically, inkjet printing may be performed in a predetermined area, and printing may be performed according to a preset pattern, resulting in a desired patterned tattoo electrode. Step S2 of dissolving and dehydrating the transfer tattoo paper, PEDOT: the thickness of the individual printed layers of PSS is 240nm, which are transferred to human skin after dehydration treatment. The water-soluble polyethylene oxide substrate is completely dissolved in water, and the silver nanowires wrapped in the conductive polymer film PEDOT: PSS are kept intact and keep the conductive property thereof. The remained substrate-free electrode can form full contact with human skin through Van der Waals force due to the ultra-thin characteristic. The tattooing electrode has washability due to the non-hydrophilicity of the conductive polymer, and can stably record brain signals for a long time. Inkjet printing can pattern various materials onto various flexible substrates by way of digital design. Furthermore, the ink jet printing has the advantages of high resolution, low cost, high accuracy and the like, and compared with the manufacturing processes of aerosol jet, photoetching and the like, the tattoo electrode has low manufacturing process cost and simple operation.
As a preferred embodiment, the preparation method further includes step S0: the conductive polymer of the tattoo electrode is coated on the magnetic nanoparticles and dissolved in a predetermined volume ratio of water to produce a high-concentration ink solution. It is understood that when the magnetic attraction layer configuration of embodiment 1 is adopted, step S0 is performed to deposit a high concentration ink solution on the dermis layer to form the magnetic attraction layer.
According to the preparation method of the tattoo electrode, the conductive layer, the transfer tattoo paper and the magnetic absorption layer are arranged, and the materials corresponding to the layers are reasonably selected, so that the light transmittance and the electric conductivity of the tattoo electrode can be enhanced by utilizing the electric conductivity and the transmissivity of the silver nanowire material in the network shape, the skin breathing is not hindered, and the influence of sweat on brain signal transmission is reduced. The conductive polymer material is not hydrophilic, so that the tattooing electrode has washability and can stably record brain signals for a long time. The magnetic absorption layer enables the electrode connector to be absorbed on the tattoo electrode for signal transmission, and improves the operation convenience of the brain-computer interface. In addition, the tattoo electrode is directly attached to the skin texture of a human body, so that the sensing area, the interface adhesive force and the stability can be increased to the maximum extent, the recording signal-to-noise ratio of an electroencephalogram signal is improved, and the problems of signal quality attenuation, motion artifacts and the like in the traditional electrode based on hard metal or conductive gel are solved. The tattoo electrode can stretch and bend along with the skin, so that the biocompatibility is improved.
Example 3
Referring to fig. 4, this embodiment specifically provides a system for preparing a tattooing electrode according to embodiment 1, which includes:
an inkjet printing module 10 for inkjet printing the conductor of the tattoo electrode on the transfer tattoo paper to generate a full polymer electrode;
and a dehydration processing module 20 for performing dissolution and dehydration processing on the transfer tattoo paper to dissolve the dissolution layer and form a support layer for supporting the conductive layer of the tattoo electrode. Preferably, the thickness of the support layer is 500 nm.
The ink jet printing module 10 ink-jet prints silver nanowires wrapped in a conductive polymer film PEDOT: PSS onto a water-soluble polyethylene oxide substrate (i.e., a dissolving layer) of a transfer printing tattoo paper adhesive layer and a support layer to obtain a full polymer electrode. Specifically, inkjet printing may be performed in a predetermined area, and printing may be performed according to a preset pattern, resulting in a desired patterned tattoo electrode. The dehydration processing module 20 performs dissolution and dehydration processing on the transfer tattoo paper, and the ratio of PEDOT: the thickness of the single printed layer of PSS is 240nm, which is transferred to human skin after dehydration treatment. The water-soluble polyethylene oxide substrate is completely dissolved in water, and the silver nanowires wrapped in the conductive polymer film PEDOT, PSS are kept intact, and the conductive property of the silver nanowires is kept. The remained substrate-free electrode can form full contact with human skin through van der waals force due to the ultra-thin characteristic. The tattooing electrode has washability due to the non-hydrophilicity of the conductive polymer, and can stably record brain signals for a long time. Inkjet printing can pattern various materials onto various flexible substrates by way of digital design. Furthermore, the ink-jet printing has the advantages of high resolution, low cost, high accuracy and the like, and compared with the manufacturing processes of aerosol jet, photoetching and the like, the tattoo electrode has the advantages of low cost and simple operation in the manufacturing process.
In a preferred embodiment, the manufacturing method further includes a magnetic attracting module 30 for coating the conductive polymer of the tattoo electrode on the magnetic nanoparticles and dissolving the conductive polymer in a predetermined volume ratio of water to generate a high-concentration ink solution. It is understood that when the magnetic attraction layer configuration of embodiment 1 is adopted, the magnetic attraction module 30 is used to deposit a high concentration ink solution on the dermis layer to form the magnetic attraction layer.
The preparation system of tattoo electrode of this embodiment is through setting up conducting layer, rendition tattoo paper and magnetism layer to and select for use the material that each layer corresponds rationally, can utilize the electric conductivity and the transmissivity of the silver nanowire material of network shape reinforcing tattoo electrode's light transmissivity and electric conductive property, and reduce the influence of sweat to brain signal transmission when not hindering skin breathing. The conductive polymer material is not hydrophilic, so that the tattooing electrode has washability and can stably record brain signals for a long time. The magnetic absorption layer enables the electrode connector to be absorbed on the tattoo electrode for signal transmission, and improves the operation convenience of the brain-computer interface. In addition, the tattoo electrode is directly attached to the skin texture of a human body, so that the sensing area, the interface adhesive force and the stability can be increased to the maximum extent, the recording signal-to-noise ratio of an electroencephalogram signal is improved, and the problems of signal quality attenuation, motion artifacts and the like in the traditional electrode based on hard metal or conductive gel are solved. The tattooing electrode can stretch and bend along with the skin, so that the biocompatibility is improved.
While specific embodiments of the invention have been described above, it will be understood by those skilled in the art that this is by way of example only, and that the scope of the invention is defined by the appended claims. Various changes and modifications to these embodiments may be made by those skilled in the art without departing from the spirit and scope of the invention, and these changes and modifications are within the scope of the invention.
Claims (10)
1. A tattoo electrode is characterized by comprising a conductive layer and transfer tattoo paper;
the conducting layer comprises a conductor wrapped by a conducting polymer, wherein the conducting polymer is PEDOT (PSS material), and the conductor is a silver nanowire; the transfer tattoo paper comprises an adhesive layer, a dissolving layer and a supporting layer; the conductive layer is used to form an all-polymer electrode by ink-jet printing the electrical conductor onto the adhesive layer and the support layer.
2. The tattoo electrode of claim 1, wherein one side of said adhesive layer is said support layer; the other side of the adhesive layer is used for attaching to human skin.
3. The tattooing electrode of claim 1, wherein said dissolving layer comprises a water-soluble polyethylene oxide substrate; the support layer comprises an ethylcellulose layer.
4. The tattoo electrode of any of claims 1-3, further comprising a magnetic attracting layer; the magnetic absorption layer comprises magnetic nanoparticles wrapped by the conductive polymer;
the magnetic layer is used for magnetically attracting the electrode connector so as to enable the electrode connector to output brain signals acquired by the tattooing electrode; the electrode connector comprises a magnetic disc, and the magnetic disc is used for enabling the magnetic absorption layer and the electrode connector to be magnetically absorbed.
5. A method for preparing a tattoo electrode, for use in preparing a tattoo electrode according to any one of claims 1-3, said method comprising:
ink-jet printing the conductor of the tattooing electrode on transfer tattooing paper of the tattooing electrode to generate an all-polymer electrode;
and performing dissolving and dewatering treatment on the transfer tattoo paper to dissolve the dissolving layer and form the supporting layer, wherein the supporting layer is used for supporting the conductive layer of the tattoo electrode.
6. The method of preparing a tattoo electrode according to claim 5, wherein the support layer has a thickness of 500 nm.
7. The method of preparing the tattoo electrode according to claim 5, for preparing the tattoo electrode according to claim 4, further comprising:
coating the conductive polymer of the tattoo electrode on the magnetic nanoparticles, and dissolving the conductive polymer in water with a preset volume proportion to generate a high-concentration ink solution; the high-concentration ink solution is used for depositing on a dermis layer to form a magnetic absorption layer.
8. A system for preparing a tattoo electrode according to any one of claims 1-3, said system comprising:
an ink jet printing module for ink jet printing the conductor of the tattoo electrode on the transfer tattoo paper of the tattoo electrode to generate a full polymer electrode;
and the dehydration treatment module is used for dissolving and dehydrating the transfer tattoo paper so as to dissolve the dissolving layer and form the supporting layer, and the supporting layer is used for supporting the conductive layer of the tattoo electrode.
9. The system for preparing a tattoo electrode according to claim 8, wherein the support layer has a thickness of 500 nm.
10. The system for preparing a tattoo electrode according to claim 8, for preparing a tattoo electrode according to claim 4, further comprising:
the magnetic suction module is used for coating the conductive polymer of the tattooing electrode on the magnetic nano particles and dissolving the conductive polymer in water with a preset volume proportion to generate a high-concentration ink solution; the high-concentration ink solution is used for depositing on a dermis layer to form a magnetic absorption layer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210197423.1A CN114768078A (en) | 2022-03-02 | 2022-03-02 | Tattoo electrode and preparation method and system thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210197423.1A CN114768078A (en) | 2022-03-02 | 2022-03-02 | Tattoo electrode and preparation method and system thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114768078A true CN114768078A (en) | 2022-07-22 |
Family
ID=82422979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210197423.1A Pending CN114768078A (en) | 2022-03-02 | 2022-03-02 | Tattoo electrode and preparation method and system thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114768078A (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050061198A1 (en) * | 2003-08-06 | 2005-03-24 | Khan Misbah H. | Magnetic ink tissue markings |
| CN102087885A (en) * | 2009-12-08 | 2011-06-08 | 中国科学院福建物质结构研究所 | Planar silver nanowire transparent conductive thin film and preparation method thereof |
| KR20160120610A (en) * | 2015-04-08 | 2016-10-18 | (주)인성정보 | Tatoo mask assembly for iontophoresis |
| US9827430B1 (en) * | 2017-02-02 | 2017-11-28 | Qualcomm Incorporated | Injected conductive tattoos for powering implants |
| CN110310763A (en) * | 2019-06-25 | 2019-10-08 | 武汉工程大学 | A kind of preparation method of the flexible transparent electrode based on PEDOT:PSS and silver nanowires |
| CN111640538A (en) * | 2020-05-27 | 2020-09-08 | 广西大学 | Preparation and transfer printing method of PEDOT (PolyEthylenediamine terephthalate): PSS (PolyEthylenediamine) substrate-free tattoo electrode |
| CN113069682A (en) * | 2021-04-07 | 2021-07-06 | 济南澜亿未来生物科技有限公司 | Semi-permanent tattoo patch, preparation method and use method thereof |
| CN113243920A (en) * | 2021-05-12 | 2021-08-13 | 北京石墨烯研究院 | Flexible attached skin electrode and preparation method and application thereof |
-
2022
- 2022-03-02 CN CN202210197423.1A patent/CN114768078A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050061198A1 (en) * | 2003-08-06 | 2005-03-24 | Khan Misbah H. | Magnetic ink tissue markings |
| CN102087885A (en) * | 2009-12-08 | 2011-06-08 | 中国科学院福建物质结构研究所 | Planar silver nanowire transparent conductive thin film and preparation method thereof |
| KR20160120610A (en) * | 2015-04-08 | 2016-10-18 | (주)인성정보 | Tatoo mask assembly for iontophoresis |
| US9827430B1 (en) * | 2017-02-02 | 2017-11-28 | Qualcomm Incorporated | Injected conductive tattoos for powering implants |
| CN110310763A (en) * | 2019-06-25 | 2019-10-08 | 武汉工程大学 | A kind of preparation method of the flexible transparent electrode based on PEDOT:PSS and silver nanowires |
| CN111640538A (en) * | 2020-05-27 | 2020-09-08 | 广西大学 | Preparation and transfer printing method of PEDOT (PolyEthylenediamine terephthalate): PSS (PolyEthylenediamine) substrate-free tattoo electrode |
| CN113069682A (en) * | 2021-04-07 | 2021-07-06 | 济南澜亿未来生物科技有限公司 | Semi-permanent tattoo patch, preparation method and use method thereof |
| CN113243920A (en) * | 2021-05-12 | 2021-08-13 | 北京石墨烯研究院 | Flexible attached skin electrode and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 江禹;马俊林;朱楠;: "柔性印刷可穿戴电化学传感器", 化学通报, no. 04, 18 April 2020 (2020-04-18) * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Liu et al. | Recent progress in flexible wearable sensors for vital sign monitoring | |
| Qiu et al. | A bioinspired, durable, and nondisposable transparent graphene skin electrode for electrophysiological signal detection | |
| Lee et al. | Self-adhesive epidermal carbon nanotube electronics for tether-free long-term continuous recording of biosignals | |
| Niu et al. | Surface bioelectric dry Electrodes: A review | |
| Li et al. | On-skin graphene electrodes for large area electrophysiological monitoring and human-machine interfaces | |
| CN103225204B (en) | Wearable flexible sensor and making method thereof | |
| Liu et al. | Silver nanowire-composite electrodes for long-term electrocardiogram measurements | |
| CN109323781A (en) | A method of preparing flexible self energizing integrated pressure sensor array | |
| CN108324274A (en) | A kind of class skin multi-channel surface myoelectric pole and preparation method thereof based on reticular structure design | |
| CN105748065A (en) | Moisture-retention microneedle matrix array surface bioelectric electrode | |
| Meng et al. | A flexible dry electrode based on APTES-anchored PDMS substrate for portable ECG acquisition system | |
| KR101392946B1 (en) | The dry bio-electrode sensor with multi stub electrodes and the fabrication method thereof | |
| CN111743529B (en) | Skin electrode and manufacturing method thereof | |
| US10966622B2 (en) | Printed ECG electrode and method | |
| CN112254630A (en) | Flexible wearable sensor with high sensitivity and high deformation range and preparation method thereof | |
| CN105232036A (en) | Medical sensor and manufacturing method thereof | |
| Xiao et al. | High-adhesive flexible electrodes and their manufacture: A review | |
| CN114279601A (en) | Flexible nano-film pressure sensor and preparation method thereof | |
| Wang et al. | Robust tattoo electrode prepared by paper-assisted water transfer printing for wearable health monitoring | |
| CN114768078A (en) | Tattoo electrode and preparation method and system thereof | |
| Tong et al. | Wearable electrochemical sensors based on nanomaterials for healthcare applications | |
| Yuwen et al. | Carbon nanotubes: a powerful bridge for conductivity and flexibility in electrochemical glucose sensors | |
| CN112932494A (en) | Epidermis dry electrode and manufacturing method thereof and epidermis electric signal acquisition device | |
| CN202960505U (en) | Disposable electrocardiogram monitoring electrode adopting conductive hydrogel | |
| CN109330590B (en) | Epidermal electrode for epidermal signal acquisition and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: No. 337 Shahe Road, Jiangqiao Town, Jiading District, Shanghai, March 2018_ Room 203 JT3300 Applicant after: Shanghai Lisha Technology Co.,Ltd. Address before: 200233 floor 21, block B, xincaohejing international business center, Xuhui District, Shanghai Applicant before: Shanghai Lisha Technology Co.,Ltd. |
|
| CB02 | Change of applicant information |