CN105748065A - Moisture-retention microneedle matrix array surface bioelectric electrode - Google Patents
Moisture-retention microneedle matrix array surface bioelectric electrode Download PDFInfo
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- CN105748065A CN105748065A CN201610044254.2A CN201610044254A CN105748065A CN 105748065 A CN105748065 A CN 105748065A CN 201610044254 A CN201610044254 A CN 201610044254A CN 105748065 A CN105748065 A CN 105748065A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/296—Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/398—Electrooculography [EOG], e.g. detecting nystagmus; Electroretinography [ERG]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/04—Constructional details of apparatus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
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- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
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Abstract
The invention relates to a moisture-retention microneedle matrix array surface bioelectric electrode.The moisture-retention microneedle matrix array surface bioelectric electrode comprises an electrode body, a signal processing module, a heat-transfer insulating thin film layer and an ultra-thin hook and loop fastener or a self-attachment thin film and is constructed through a 3D or die casting mode.The electrode body is a hollow cylinder or elliptic cylinder and is internally provided with a cavity used for storing liquid electrolyte, a solid or hollow microneedle array is distributed on the upper surface of the electrode body, a series of micropores are formed between microneedles, the surface of the electrode body is plated with silver, gold or platinum and other conductive metal through a chemical plating method, an electrochemical deposition method, a vacuum evaporation method or a magnetron sputtering method or other methods, the back side of the electrode body is provided with the signal processing module provided with a voltage follower, and a voltage follower circuit is encapsulated by heat-transfer insulating glue and attached to the ultra-thin hook and loop fastener or the self-attachment thin film.The moisture-retention microneedle matrix array surface bioelectric electrode has the denoising and moisture retention functions, and improves stability of bioelectric signal acquisition.
Description
Technical field
The present invention relates to bio electricity electro-technical field, particularly relate to a kind of moisturizing micropin matrix array surface biological electricity electrode.
Background technology
When carrying out medical diagnosis and research, it is necessary to the internal electromotive force of tester is measured and record, it is required for when carrying out bio electricity monitoring adopting electrode to contact with human body
Clinical a large amount of electrode used is the disposable Ag/Agcl electrode with conductive paste at present, and electrode slice is usually directly pasted and detected position accordingly at health by physiological signal dynamic acquisition, then passes through wire by physiological signal transmission to signal processor.This type of mode has the disadvantage that
(1) needing to use conductive paste to paste on skin by electrode slice, the existence of conductive paste can make some detected persons not feel well, and even causes skin allergy, festers or the symptom such as inflammation.
(2) due to the existence of conductive paste, if for the monitoring of long-term physiological signal, conductive paste can become dry gradually in dehydration on the one hand, it is easy to causes the sharply change with contact impedance that comes off of electrode, affects stablizing of signal.
(3) owing to the Ag/Agcl electrode with conductive paste is easy to fall off, clinical measurement can only be carried out, it is impossible to realize the collection under the real-time status such as motion and monitoring.
(4) the disposable Ag/Agcl electrode with conductive paste, uses and is once just dropped, during use costly.
Summary of the invention
For the deficiency that prior art exists, the present invention provides a kind of to be had noise reduction and moisture-keeping functions, can be used for the moisturizing micropin matrix array surface biological electricity electrode of the collection of the bioelectrical signals such as electrocardio, brain electricity, eye electricity and myoelectricity.
For this, technical scheme is as follows:
For solving the problems referred to above, the moisturizing micropin matrix array surface biological electricity electrode package of the present invention is containing electrode body, signal processing circuit module, heat conducting insulating film layer and ultra-thin VELCRO or self-adhering film, a cavity is had inside electrode body, microneedle array and the microwell array of entity or hollow it is arranged with at electrode body upper surface, conductive metal film is had at electrode body and microneedle surface, being signal processing circuit module at the electrode body back side, signal processing circuit module is encapsulated and is pasted onto by heat conducting insulating film layer on one piece of ultra-thin VELCRO or self-adhering film.
Described electrode body be shaped as cylinder or ellipsoidal configuration, adopt 3D to print or the manufacture method of model casting method, material selection photosensitive resin that 3D prints, PLA, ABS resin etc..
Described electrode is hollow, containing cavity inside electrode body, it is possible to store liquid electrolyte, and liquid electrolyte can pass through hollow microneedles or micropore permeation between electrode and skin.
Another kind of improvement as the present invention, in the microneedle array of entity or hollow and microwell array, micropore number is 4-64, micropin number is 4-64, described micropin is entity or hollow, the height of micropin is at 150-500 μm, the diameter of micropin is 100-500 μm, and the aperture of hollow microporous is at 50-100 μm, and the top of micropin is taper or semicircle.
There is conductive metal film on described electrode body and the surface of microneedle array, conductive metal film is to be prepared by methods such as electroless plating method, electrochemical deposition method, vacuum vapour deposition or magnetron sputtering methods, and its surface can be metal or the metal compound films such as silver, gold, platinum, yttrium oxide, silver/silver chloride
Another kind of improvement as the present invention, signal processing circuit module has the voltage follower strengthening input impedance, connecting with adhesive glue between signal processing circuit module and electrode body, the voltage follower on signal place circuit module adopts the heat conducting insulating film layer encapsulation of resin or insullac in the side deviating from electrode body.Voltage follower circuit in signal processing circuit module is welded in flexibility or hard substrate, has three wires above, is connected with power positive cathode and output signal respectively
The side of described electrode body has for the electrolytical hole of injecting fluid, and opposite side has wire or conductive silver glue to make electrode surface conductive metal film form path with signal processing circuit module.
Described electrode is contained in VELCRO one piece ultra-thin or on bioadhesive patch, it is possible to be combined with any wearable product freely
Compared with prior art, this moisturizing micropin matrix array surface biological electricity electrode is by the micropin of electrode body the upper surface solid or hollow of distribution and hollow microporous, can the liquid electrolyte being stored in electrode body cavity be penetrated between electrode and skin, the effect of row moisturizing can be played, be effectively improved the stability that bioelectrical signals is collected.Lower surface at electrode body is connected to signal processing circuit module, and the voltage follower in signal processing circuit module can increase input impedance.Ultra-thin VELCRO is used or from bioadhesive patch, it is ensured that this wet micropin matrix array surface biological electricity electrode can be combined with wearable product freely, it is possible to collects required physiological signal, has great convenience at electrode base.This wet micropin matrix array surface biological electricity electrode can reuse simultaneously, compares the use of the disposable Ag/Agcl electrode with conductive paste and is once just dropped, and this electrode utilization rate is higher, also more environmentally-friendly.
Accompanying drawing explanation
Below in conjunction with the drawings and specific embodiments, the present invention is further detailed explanation:
Fig. 1 is the structural representation of an embodiment of moisturizing micropin matrix array surface biological electricity electrode of the present invention；
Fig. 2 is the plan structure schematic diagram of an embodiment of moisturizing micropin matrix array surface biological electricity electrode of the present invention；
Fig. 3 is the structural representation of another embodiment of moisturizing micropin matrix array surface biological electricity electrode of the present invention；
Fig. 4 is the plan structure schematic diagram of another embodiment of moisturizing micropin matrix array surface biological electricity electrode of the present invention；
Fig. 5 be moisturizing micropin matrix array surface biological electricity electrode of the present invention an embodiment in the structural representation of signal processing module；
Fig. 6 be moisturizing micropin matrix array surface biological electricity electrode of the present invention an embodiment in the fundamental diagram of voltage follower；
Detailed description of the invention
Below in conjunction with embodiment and accompanying drawing thereof in detail the present invention is described in detail, but the present invention should not be limited by the examples:
The one of the present invention wets micropin matrix array surface biological electricity electrode (referring to Fig. 1-4), including electrode body 1, signal processing moding circuit block 2, heat conducting insulating film layer 3 and ultra-thin VELCRO or 4 four parts of self-adhering film.Wherein there is a cavity 5 inside electrode body, cavity 5 is used for storing liquid electrolyte, be arranged with micropin 6 array and micropore 7 array of entity or hollow at electrode body upper surface, the liquid electrolyte in cavity 5 can be penetrated to the skin and between electrode by micropin 6 array of hollow and micropore 7 array.Conductive metal film 8 is had at electrode body 1 upper surface and micropin 6 surface, it is signal processing circuit module 2 at the electrode body back side, signal processing circuit module 2 is encapsulated by heat conducting insulating film layer 3 and is pasted onto on one piece of ultra-thin VELCRO or self-adhering film 4, voltage follower circuit 12 in signal processing circuit module 2 is welded in flexibility or hard substrate, wire 14, the 15 and 16 respectively positive and negative joint of power supply and output Signal connector.On the left of electrode, there is one for the electrolytical hole 10 of injecting fluid, on the right side of electrode, have the wire or conductive silver glue 9 that are connected with signal processing circuit module 2 by electrode surface conductive metal film 8.
In the present embodiment, electrode body 1 be shaped as cylinder or ellipsoid, adopt 3D to print or model casting method, material selection photosensitive resin that 3D prints, PLA, ABS resin etc..
One moisturizing micropin matrix array surface biological electricity electrode of the present invention is divided into band entity micropin and band hollow microneedles two kinds, the structure of the moisturizing micropin matrix array surface biological electricity electrode with entity micropin is as it is shown in figure 1, liquid electrolyte can be merely able to be penetrated to the skin and between electrode by hollow microporous 7；Moisturizing micropin matrix array surface biological electricity electrode structure with hollow microneedles is as shown in Figure 3, liquid electrolyte can pass through hollow microneedles 6 and micropore 7 penetrates to the skin and between electrode, the electrode of two kinds of structures can play the effect of moisturizing, improve the stability of bioelectrical signals.
The top view of the moisturizing micropin matrix array surface biological electricity electrode with entity micropin of the present invention a kind of moisturizing micropin matrix array surface biological electricity electrode is as shown in Figure 2, the top view of the moisturizing micropin matrix array surface biological electricity electrode with hollow microneedles is as shown in Figure 4, the distribution of electrode body 1 upper surface has micropin 6 array and micropore 7 array of entity or hollow, wherein micropore number is 4-64, micropin number is 4-64, described micropin is entity or hollow, the height of micropin is at 150 μm to 500 μm, the diameter of micropin is 100 μm to 500 μm, the aperture of hollow microporous is at 50 μm to 100 μm, the top of micropin is taper or semicircle.
In the present embodiment, there is conductive metal film 8 on the surface of electrode body 1 and micropin 5 array, conductive metal film 8 is to be prepared by methods such as electroless plating method, electrochemical deposition method, vacuum vapour deposition or magnetron sputtering methods, and the metal on its surface and metallic compound can be metal or the metal compound films such as silver, gold, platinum, yttrium oxide, silver/silver chloride.
In the present embodiment, electrode base uses ultra-thin VELCRO or self-adhering film 4, it is ensured that this moisturizing micropin matrix array surface biological electricity electrode can be combined with wearable product freely, it is possible to collects required physiological signal, has great convenience.
The present invention a kind of moisturizing micropin matrix array surface biological electricity electrode signal processing circuit module 2 structure distribution as it is shown in figure 5, in signal processing circuit module 2 distribution have voltage follower 12, connect positive source wire 13, connect power cathode wire 14 and connect output voltage wire 15.Being connected with adhesive glue between signal processing circuit module 2 and electrode body 1, the voltage follower 12 in signal processing circuit module 2 adopts the heat conducting insulating film layer 3 of resin or insullac to encapsulate in the side deviating from electrode body 1.Voltage follower 12 operation principle in the signal processing circuit module 2 of the present invention a kind of moisturizing micropin matrix array surface biological electricity electrode is as shown in Figure 6, the inside of voltage follower 12 includes power supply coupling capacitor device C, current-limiting resistance R1, resistance R2, supply voltage VCC and output voltage Vo, adopts voltage follower 12 to be connected with electrode body and can effectively increase the input impedance of electrode.
Claims (8)
- null1. a moisturizing micropin matrix array surface biological electricity electrode，It is characterized in that: include electrode body (1)、Signal processing module (2)、Heat conducting insulating film layer (3)、Ultra-thin VELCRO or self-adhering film (4)、It is included in the cavity (5) that electrode body (1) is internal、It is fixed on micropin (6) array and micropore (7) array of electrode body (1) upper surface entity or hollow、It is coated in the conductive metal film (8) of electrode body (1) and micropin (6) array surface，Described signal processing module (2) is in electrode body (1) back side，Signal processing module (2) is encapsulated and is pasted onto by heat conducting insulating film layer (3) on one piece of ultra-thin VELCRO or self-adhering film (4)，Signal processing module 2 (on) voltage follower circuit (12) be welded in flexibility or hard substrate，Wire (14) and (15) are the positive and negative joint of power supply，Wire (16) is output Signal connector.
- 2. moisturizing micropin matrix array surface biological electricity electrode according to claim 1, it is characterized in that: electrode body (1) is shaped as cylinder or ellipsoidal configuration, adopting the manufacture method of 3D printing or model casting method, 3D printed material selects photosensitive resin, PLA, ABS resin etc..
- 3. moisturizing micropin matrix array surface biological electricity electrode according to claim 1, it is characterized in that: the distribution of electrode body (1) upper surface has micropin (6) array and micropore (7) array of entity or hollow, wherein micropore number is 4-64, micropin number is 4-64, described micropin is entity or hollow, the height of micropin is at 150-500 μm, the diameter of micropin is 100-500 μm, the aperture of hollow microporous is at 50-100 μm, and the top of micropin is taper or semicircle.
- 4. moisturizing micropin matrix array surface biological electricity electrode according to claim 1, it is characterized in that: described electrode is hollow, internal containing cavity (5) at electrode body (1), can storing liquid electrolyte, liquid electrolyte can pass through hollow microneedles or micropore permeation between electrode and skin.
- 5. moisturizing micropin matrix array surface biological electricity electrode according to claim 1, it is characterized in that: signal processing module (2) has the voltage follower (12) strengthening input impedance, being connected with adhesive glue between signal processing module (2) and electrode body (1), the voltage follower (12) on signal processing module (2) adopts heat conducting insulating film layer (3) encapsulation of resin or insullac in the side deviating from electrode body (1).
- 6. moisturizing micropin matrix array surface biological electricity electrode according to claim 1, it is characterised in that: electrode is contained on VELCRO one piece ultra-thin or self-adhering film (4), it is possible to be combined with any wearable product freely.
- 7. moisturizing micropin matrix array surface biological electricity electrode according to claim 1, it is characterized in that: there is conductive metal film (8) on the surface of electrode body (1) and micropin (5) array, conductive metal film (8) is to be prepared by methods such as electroless plating method, electrochemical deposition method, vacuum vapour deposition or magnetron sputtering methods, and its surface can be metal or the metal compound films such as silver, gold, platinum, yttrium oxide, silver, silver chloride.
- 8. moisturizing micropin matrix array surface biological electricity electrode according to claim 1, it is characterized in that: have in the side of electrode body (1) for the electrolytical hole of injecting fluid (10), opposite side has wire or conductive silver glue (9) to make electrode surface conductive metal film (8) form path with signal processing module (2).
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Cited By (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106388807A (en) * | 2016-08-30 | 2017-02-15 | 中国科学院深圳先进技术研究院 | Preparation method for surface adhesive electrode array |
| CN106955103A (en) * | 2017-05-03 | 2017-07-18 | 彭德科 | Disposable facial nerve monitoring electrode assembly |
| CN107684417A (en) * | 2016-08-04 | 2018-02-13 | 云南科威液态金属谷研发有限公司 | Injecting type microneedle electrodes based on liquid metal fluid channel and preparation method thereof |
| WO2018109758A1 (en) * | 2016-12-15 | 2018-06-21 | Tech Innosphere Engineering Ltd. | Brush electrode |
| CN108784677A (en) * | 2018-06-22 | 2018-11-13 | 厦门大学 | A kind of method of the magnetic field assistant laser processing of biomedical electrode |
| CN109044329A (en) * | 2018-09-13 | 2018-12-21 | 天津工业大学 | A kind of multifunctional bio electric transducer |
| CN109124626A (en) * | 2018-07-26 | 2019-01-04 | 天津大学 | Novel passive flexible optical electrode |
| CN109330711A (en) * | 2018-11-19 | 2019-02-15 | 广东中昇华控智能科技股份有限公司 | A kind of porous metals capillary sepage microneedle electrodes and preparation method |
| CN110063713A (en) * | 2018-01-24 | 2019-07-30 | 伟伦公司 | Physiological parameter monitor with fixing seat and the EM equipment module that can be removably attaching in fixing seat |
| CN110072450A (en) * | 2018-02-28 | 2019-07-30 | 北京布润科技有限责任公司 | A kind of bioelectricity acquisition electrode and brain wave acquisition cap |
| WO2020147556A1 (en) * | 2019-01-15 | 2020-07-23 | 浙江强脑科技有限公司 | Hydrogel reservoir electroencephalogram electrode |
| CN112631425A (en) * | 2020-12-21 | 2021-04-09 | 上海交通大学 | Microneedle array type brain-computer interface device and preparation method thereof |
| CN115349876A (en) * | 2022-09-22 | 2022-11-18 | 北京市神经外科研究所 | Wearable wireless facial myoelectricity collection system and myoelectricity collection system |
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| CN110063713A (en) * | 2018-01-24 | 2019-07-30 | 伟伦公司 | Physiological parameter monitor with fixing seat and the EM equipment module that can be removably attaching in fixing seat |
| CN110072450B (en) * | 2018-02-28 | 2022-05-20 | 北京布润科技有限责任公司 | Bioelectricity collection electrode and electroencephalogram collection cap |
| CN110072450A (en) * | 2018-02-28 | 2019-07-30 | 北京布润科技有限责任公司 | A kind of bioelectricity acquisition electrode and brain wave acquisition cap |
| CN108784677A (en) * | 2018-06-22 | 2018-11-13 | 厦门大学 | A kind of method of the magnetic field assistant laser processing of biomedical electrode |
| CN109124626B (en) * | 2018-07-26 | 2021-11-23 | 天津大学 | Novel passive flexible optical electrode |
| CN109124626A (en) * | 2018-07-26 | 2019-01-04 | 天津大学 | Novel passive flexible optical electrode |
| CN109044329A (en) * | 2018-09-13 | 2018-12-21 | 天津工业大学 | A kind of multifunctional bio electric transducer |
| CN109330711A (en) * | 2018-11-19 | 2019-02-15 | 广东中昇华控智能科技股份有限公司 | A kind of porous metals capillary sepage microneedle electrodes and preparation method |
| WO2020147556A1 (en) * | 2019-01-15 | 2020-07-23 | 浙江强脑科技有限公司 | Hydrogel reservoir electroencephalogram electrode |
| CN112631425A (en) * | 2020-12-21 | 2021-04-09 | 上海交通大学 | Microneedle array type brain-computer interface device and preparation method thereof |
| CN115349876A (en) * | 2022-09-22 | 2022-11-18 | 北京市神经外科研究所 | Wearable wireless facial myoelectricity collection system and myoelectricity collection system |
| CN115349876B (en) * | 2022-09-22 | 2023-09-15 | 北京市神经外科研究所 | Myoelectricity acquisition system |
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