CN109124626A - Novel passive flexible optical electrode - Google Patents
Novel passive flexible optical electrode Download PDFInfo
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- CN109124626A CN109124626A CN201810837807.9A CN201810837807A CN109124626A CN 109124626 A CN109124626 A CN 109124626A CN 201810837807 A CN201810837807 A CN 201810837807A CN 109124626 A CN109124626 A CN 109124626A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
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Abstract
The invention discloses a kind of novel passive flexible optical electrodes, are made of optical sensitive device (1), flexible probe (2), matrix (4), conductance connection layer (5) and (7) five part of transition zone；Wherein: in flexible probe (2) array insertion matrix (4), the flexible probe (2) includes free end and bottom end, free end is directly contacted with organism, and bottom end passes through transition zone (7) and is bonded with conductance connection layer (5)；Conductance connection layer (5) is set to the upper surface of transition zone (7)；The electrode slot structure formed on conductance connection layer (5), as the interface with optical sensitive device (1).The present invention significantly reduces hair interference and the contact impedance between electrode and scalp, and it is integrated with optical sensitive device, remove noise jamming and motion artifacts caused by conducting wire, electric light sensing sensitivity and compatibility are improved, realizes the wearable EEG signals detection steady in a long-term based on optical principle.
Description
Technical field
The present invention relates to be applied to the novel passive flexible optical electrode technology field of human body surface biology electro-detection and micro-
The detection field of weak low frequency EEG signals, more particularly to it is a kind of based on electrooptic effect, can be used for the passive flexibility of brain electro-detection
Optical electrode.
Background technique
Brain electricity is the external expressive form of inside of human body nerve cell activity, and as a kind of most basic physiological phenomenon it
One, medical clinic applications, disease prevention, brain-computer interface and in terms of have major application value and study meaning
Justice.Brain electricity belongs to faint low frequency signal, only only microvolt magnitude, so just needing to improve detection accuracy to biological detection
Electrode proposes higher performance indicator.
Currently used biological detection electrode has traditional Ag/Agcl electrode, microneedle electrodes, flexible substrate electrode, foam
Structure electrode, weaving flexible electrode etc..But there are still the defects of different aspect in EEG signals detection for they, such as:
1) traditional Ag/Agcl electrode using metal due to, as main part, causing its anti-interference ability weak, sensitivity
It is low, and due to the presence of Signa Gel, it easily causes skin sensitivity, be unfavorable for long-time brain electro-detection.
2) microneedle electrodes avoid the cuticula of high impedance, to greatly reduce contact due to being penetrated into conductivity meter dermatotome
Impedance embodies good performance in signal acquisition, but because of the otherness of preparation process complexity and Different Individual cuticula, no
Conducive to popularization and use.
3) flexible substrate electrode, foaming structure electrode and weaving flexible electrode have good application performance on wearable,
And stability is good, but interference problem caused by hair can not be overcome in EEG measuring, influences the quality of EEG signals.
In addition, the dry electrode of traditional biological is mainly used in the brain electricity detecting system of electrical method, the brain under complex environment
There is a problem of that signal fidelity is low, anti-electromagnetic interference capability is weak and the rich degree of information characteristics is limited in electro-detection.
There is big advantage on improving anti-interference and precision based on the EEG measuring of optical principle, it is in recent years, external
Has the method for carrying out brain electro-detection using the electrooptic effect of optical crystal, but in the detection process can be by the limit of conventional dry electrode
The not high problem of electric light sensing compatibility is made and encountered, the extraction of high s/n ratio EEG signals is influenced.Therefore, a kind of application is invented
In the bioelectrode of optical principle measurement brain electricity, it is necessary with improving electric light sensing compatibility and sensitivity.
In the prior art, patent No. CN204351823U discloses " bioelectricity acquires dry electrode ".This patent describe
" human body surface bioelectricity is obtained using flat bowl cap, conductive channel is input to the buffering on circuit board using more leg structures
Circuit, rear end conducting wire are connect with buffer circuit.The patent can effectively improve bioelectric acquisition stability and reliability.But
High impedance caused by hair can not be overcome the problems, such as in brain electro-detection, and due to joined signal buffer circuit, leads to complicated ring
The electrometric signal-to-noise ratio decline of border hypencephalon, is unable to satisfy the passive requirement in acquisition system front end."
Patent No. CN107411735A discloses " a kind of bioelectrical signals flexibility dry-type electrode and preparation method thereof ".This is specially
Benefit describes that " electrode is made of electrode body and electrical interconnecting means.Electrode body uses flexible composite, and is prepared into three arc maintenances
Shape curved surface is bonded with skin surface, improves the stability and comfort level of acquisition signal, and electrical interconnecting means are adopted with electrode body
It is integrally poured with integral forming process, effectively reduces electrical interconnecting means-electrode body contact impedance, be conducive to measuring circuit
Connection.But because of whole fitting, the precision of brain electro-detection is seriously affected in hotspots, and due to needing to draw in measurement process
The external electro-optical device of line, the compatibility for causing electric light to sense is insufficient."
Summary of the invention
For in the patent of above-mentioned earlier application, electrode signal-to-noise ratio present in bioelectricity collection process is low, electric light passes
The problem for feeling sensitivity and compatibility deficiency, the invention proposes a kind of novel passive flexible optical electrode, whole design is to protect
It demonstrate,proves EEG signals and stablizes transmission in detection transmission process, allow between matrix, conductance connection layer and optical sensitive device in sandwich
Structure.
The present invention proposes a kind of novel passive flexible optical electrode, by optical sensitive device 1, flexible probe 2, matrix 4, electricity
Lead layer 5 and 7 five part of transition zone composition；Wherein: in 2 array of the flexible probe insertion matrix 4, the flexible probe 2
Including free end and bottom end, free end is directly contacted with organism, and bottom end passes through transition zone 7 and is bonded with conductance connection layer 5；The electricity
Lead layer 5 is set to the upper surface of transition zone 7；It is provided on conductance connection layer 5 according to array-type flexible probe positions shape
At electrode slot structure, as the interface with optical sensitive device 1.
It further include electrostatic screen layer 6, the optical sensitive device 1 is placed in electrostatic screen layer 6.
The flexible probe 2 has to be led to by the conduction that poly- arsenic coughs up the realization ion constituted of graphite ene coatings 3 and electron exchange
Road.
It is integrally formed according to the flexible probe 2 with matrix 4.
A transition zone 7 is also set up between the conductance connection layer 5 and matrix 4；The poly- arsenic coughs up graphene layer 3 across the mistake
Layer 7 is crossed tightly to be bonded with conductance connection layer 5.
Optionally, the array architecture of the flexible probe 2 is set as angled.
Optionally, 2 one layer of chitosan of laying on the flexible probe.
Optionally, lead channel is set up between the electrode slot structure, it is whole to be used as integrated design.
Compared with prior art, the present invention significantly reduces hair interference and the contact impedance between electrode and scalp,
And it is integrated with optical sensitive device, remove conducting wire caused by noise jamming and motion artifacts, improve electric light sensing sensitivity and
Compatibility realizes the wearable EEG signals detection steady in a long-term based on optical principle.
Appended drawing reference
Fig. 1 is novel passive flexible optical electrode structure schematic diagram of the invention；
Fig. 2 is novel passive flexible optical electrode sectional view of the invention；
Fig. 3 is novel passive flexible optical electrode pictorial diagram of the invention；
Fig. 4 is that conductance of the invention joins layer and optical sensitive device structural schematic diagram.
1, optical sensitive device, 2, flexible probe, 3, poly- arsenic cough up graphite ene coatings, 4, matrix, 5, conductance join layer, 6, electrostatic
Shielded layer, 7, transition zone, 11, signal input port, 12, optic fibre input end mouth, 13, optical fiber output port, 51, slot electrode knot
Structure.
Specific embodiment
Specific embodiments of the present invention are described in further detail below in conjunction with attached drawing.Wherein, to described unknown
True parameter, technical staff can refer to the prior art and understand to realize.
As depicted in figs. 1 and 2, a kind of novel passive flexible optical electrode of the invention includes made of PDMS polymer
Flexible probe 2；With PDMS matrix 4 it is support level in 2 rear end of flexible probe, it is direct is embedded into 2 array of flexible probe matrix 4
It is contacted with the conductance connection layer 5 that golden film is formed.For the adhesiveness for increasing golden film and matrix 4, one layer of flexibility can be added therebetween
PI polymer is as transition zone 7；Simultaneously to increase the contact area with golden film, contact impedance is reduced, poly- arsenic coughs up graphite ene coatings 3
Tightly it is bonded with the golden film for being vaporized on 7 surface of transition zone at disc type.
By optical sensitive device (1), flexible probe (2), matrix (4), conductance connection layer (5) and (7) five part group of transition zone
At；Wherein: in flexible probe (2) array insertion matrix (4), the flexible probe (2) includes free end and bottom end, from
It is directly contacted with organism by holding, bottom end passes through transition zone (7) and is bonded with conductance connection layer (5)；Conductance connection layer (5) is set to
The upper surface of transition zone (7)；The slot electrode formed according to array-type flexible probe positions is provided on conductance connection layer (5)
Structure, as the interface with optical sensitive device (1)
Further, in the structure of the novel passive flexible optical electrode of the present embodiment, flexible probe is directly embedded into matrix
In, and be integrally formed with matrix, to increase the stability of flexible probe.The flexible probe is coughed up graphite ene coatings using poly- arsenic and is made
Eeg signal acquisition is greatly improved using its high conductivity and carrier mobility for the conductive channel of ion and electron exchange
Intensity.When implementation, as a preference, flexible probe use array architecture, and can open it is angled, to reduce intensive head
The impedance of region bring and interference are sent out, detection flexibility and comfort level are improved.One layer of chitosan is optionally laid on flexible probe,
To increase the effect with the hydration levels of skin and sterilization.According to the one side of invention, using flexible material conduct
Base layer is used to support.Optionally, above-mentioned flexible material is related to foam, PDMS polymer, rubber, silica gel.Preferably, with one
Layer transition material is coated on base layer, and wherein transition material is related to PI polymer, TiO2/TiN2 etc., to guarantee preparation process
Adhesiveness with matrix and conductance connection layer is increased, improves signal acquisition stability.It is according to the present invention another when further implementing
Aspect, MEMS technology can be used for conductance connection layer and respective optical Sensitive Apparatus integrated molding designs, wherein optical sensitive device
More particularly to MEMS electro-optical device and other fine tuning systems, transducer architecture (optical crystal, optical waveguide structure).It can as one kind
Choosing, conductance connection layer are related to the transparent soft of common metal film (conductive materials such as gold, silver, copper), nano wire and conducting polymer preparation
Property electrode chip architecture etc..And conductance connection layer can be made into slot electrode array structure, it is corresponding with the flexible probe array structure.Electrode
Also it can refer to optical sensitive device between slot and set up lead channel, so as to integrated from different optical sensitive devices, raising
Electric light sensing compatibility and sensitivity.When further implementing, electrode outer surface increases electrostatic protection layer, so as to electrostatic isolation and dress
With use.The electrostatic protection layer preferentially selects insulating textile cloth, insulation silica gel, rubber material.
As shown in figure 4, optical sensitive device in the present invention is to select a kind of LiNbO3 electrooptic modulator of M-Z model to be
Example: selection x cuts LiNbO of the y to propagation3Substrate, golden film forms conductive channel using whole coverage mode, thereon according to array
Flexible probe position forms two electrode slot structures 51, realizes, modulation integrated with the corresponding signal input port 11 of electrooptic modulator
The two sides integrated optical fiber input 12 of device, output port 13 are used as modulator carrier channel mouth.
The present invention solve during the brain wave acquisition based on optical principle contact impedance between existing scalp and electrode it is high,
Stability is poor, motion artifacts are obvious and electric light sensing is compatible and under-sensitive problem, effectively improves the letter of brain wave acquisition
It makes an uproar ratio.
Above embodiments are to specific descriptions of the invention.But it is to be appreciated that the invention is not limited to above-mentioned tools
The embodiment of body, it is without restrictive.Those skilled in the art under the inspiration of the present invention, do not depart from present inventive concept
The corresponding deformation made under the premise of theory, belongs within protection scope.
Claims (8)
1. a kind of novel passive flexible optical electrode, which is characterized in that by optical sensitive device (1), flexible probe (2), matrix
(4), conductance connection layer (5) and (7) five part of transition zone composition；Wherein: in flexible probe (2) array insertion matrix (4),
The flexible probe (2) includes free end and bottom end, and free end is directly contacted with organism, and bottom end passes through transition zone (7) and electricity
Lead layer (5) fitting；Conductance connection layer (5) is set to the upper surface of transition zone (7)；It is arranged on conductance connection layer (5)
The electrode slot structure that with good grounds array-type flexible probe positions are formed, as the interface with optical sensitive device (1).
2. novel passive flexible optical electrode as described in claim 1, which is characterized in that further include electrostatic screen layer (6), institute
Optical sensitive device (1) is stated to be placed in electrostatic screen layer (6).
3. novel passive flexible optical electrode as claimed in claim 1 or 2, which is characterized in that the flexible probe (2) has
The conductive channel of realization ion and electron exchange that graphite ene coatings (3) are constituted is coughed up by poly- arsenic.
4. novel passive flexible optical electrode as claimed in claim 1 or 2, which is characterized in that according to the flexible probe (2)
It is integrally formed with matrix (4).
5. novel passive flexible optical electrode as claimed in claim 3, which is characterized in that conductance connection layer (5) and matrix
(4) transition zone (7) are also set up between；The poly- arsenic cough up graphene layer (3) across the transition zone (7) tightly with the conductance
Join layer (5) fitting.
6. novel passive flexible optical electrode as claimed in claim 1 or 2, which is characterized in that optional, the flexible probe
(2) array architecture is set as angled.
7. novel passive flexible optical electrode as claimed in claim 1 or 2, which is characterized in that optional, the flexible probe
Upper (2) are laid with one layer of chitosan.
8. novel passive flexible optical electrode as claimed in claim 1 or 2, which is characterized in that optional, the slot electrode knot
Lead channel is set up between structure, it is whole to be used as integrated design.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810837807.9A CN109124626B (en) | 2018-07-26 | 2018-07-26 | Novel passive flexible optical electrode |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810837807.9A CN109124626B (en) | 2018-07-26 | 2018-07-26 | Novel passive flexible optical electrode |
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| Publication Number | Publication Date |
|---|---|
| CN109124626A true CN109124626A (en) | 2019-01-04 |
| CN109124626B CN109124626B (en) | 2021-11-23 |
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| CN201810837807.9A Active CN109124626B (en) | 2018-07-26 | 2018-07-26 | Novel passive flexible optical electrode |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111096742A (en) * | 2019-12-13 | 2020-05-05 | 开封市学国生物科技有限公司 | 3D chronic brain electrode adjusting device for experiments |
| CN113261968A (en) * | 2021-05-17 | 2021-08-17 | 派尼尔科技（天津）有限公司 | Flexible lithium niobate thin film electroencephalogram detection chip and device |
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| CN113261968A (en) * | 2021-05-17 | 2021-08-17 | 派尼尔科技（天津）有限公司 | Flexible lithium niobate thin film electroencephalogram detection chip and device |
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| CN109124626B (en) | 2021-11-23 |
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