CN105748065B - A kind of moisturizing micropin matrix array surface biological electricity electrode - Google Patents

Abstract

The invention relates to a surface bioelectric electrode of a moisture-retaining microneedle matrix array. The bioelectric electrode on the surface of the moisturizing microneedle matrix array includes an electrode body, a signal processing module, a thermally conductive insulating film layer, and an ultra-thin Velcro or self-adhesive film, which is constructed by 3D or model casting; the electrode body is a hollow cylinder Body or elliptical cylinder, with a cavity inside for storing liquid electrolyte, solid or hollow microneedle arrays are arranged on the upper surface, a series of micropores are distributed between the microneedles, through electroless plating, electrochemical deposition, vacuum Evaporation method or magnetron sputtering method is used to plate conductive metals such as silver, gold, or platinum on the surface of the electrode body. The back of the electrode body is a signal processing module with a voltage follower. The voltage follower circuit is encapsulated by heat-conducting insulating glue. And stick on a piece of ultra-thin velcro or self-adhesive film. The bioelectric electrode on the surface of the moisture-retaining microneedle matrix array has the functions of noise reduction and moisture retention, and improves the stability of bioelectric signal collection.

Description

A Moisturizing Microneedle Matrix Array Surface Bioelectrical Electrode

technical field

The invention relates to the technical field of bioelectricity, in particular to a bioelectric electrode on the surface of a moisturizing microneedle matrix array.

Background technique

In medical diagnosis and research, it is necessary to measure and record the potential in the body of the examiner, and it is necessary to use electrodes to contact the human body when performing bioelectricity monitoring.

At present, the electrodes widely used in clinical practice are disposable Ag/Agcl electrodes with conductive paste. The dynamic acquisition of physiological signals is usually by directly pasting the electrode pads on the corresponding detection parts of the body, and then transmitting the physiological signals to the signal processor through wires. This type of method has the following disadvantages:

(1) It is necessary to use conductive paste to stick the electrode sheet on the skin. The presence of conductive paste will make some subjects feel uncomfortable, and even cause symptoms such as skin allergies, ulceration or inflammation.

(2) Due to the existence of conductive paste, if it is used for long-term physiological signal monitoring, on the one hand, the conductive paste will gradually dehydrate and dry, which will easily cause the electrode to fall off and the sharp change of contact impedance, which will affect the stability of the signal.

(3) Since the Ag/Agcl electrode with conductive paste is easy to fall off, it can only be used for clinical measurement, and cannot realize the acquisition and monitoring in real-time conditions such as exercise.

(4) Disposable Ag/Agcl electrodes with conductive paste are discarded after one use, and the cost is higher when used.

Contents of the invention

Aiming at the deficiencies in the prior art, the present invention provides a moisturizing microneedle matrix array surface bioelectric electrode with functions of noise reduction and moisturizing, which can be used for collecting bioelectric signals such as electrocardiogram, electroencephalogram, oculoelectricity and myoelectricity.

For this reason, technical scheme of the present invention is as follows:

In order to solve the above-mentioned problems, the bioelectric electrode on the surface of the moisturizing microneedle matrix array of the present invention includes an electrode body, a signal processing circuit module, a thermally conductive insulating film layer, and an ultra-thin Velcro or self-adhesive film. There is a cavity inside the electrode body. There are solid or hollow microneedle arrays and microhole arrays arranged on the upper surface of the main body. There is a conductive metal film on the surface of the electrode body and the microneedles. On the back of the electrode body is a signal processing circuit module. The signal processing circuit module is encapsulated by a thermally conductive insulating film layer and Attaches to a piece of ultra-thin velcro or self-adhesive film.

The shape of the electrode body is a cylinder or an ellipsoid structure, and the manufacturing method is 3D printing or model casting method, and the material for 3D printing is selected from photosensitive resin, PLA, ABS resin and the like.

The electrode is hollow and contains a cavity inside the electrode body, which can store liquid electrolyte, and the liquid electrolyte can penetrate between the electrode and the skin through hollow microneedles or micropores.

As another improvement of the present invention, the number of microholes in the solid or hollow microneedle array and the microhole array is 4-64, and the number of microneedles is 4-64. The microneedles are solid or hollow, and the microneedles are solid or hollow. The height of the needle is 150-500 μm, the diameter of the microneedle is 100-500 μm, the diameter of the hollow microhole is 50-100 μm, and the tip of the microneedle is conical or semicircular.

There is a conductive metal film on the surface of the electrode body and the microneedle array, and the conductive metal film is prepared by methods such as chemical plating, electrochemical deposition, vacuum evaporation or magnetron sputtering, and its surface can be silver, Gold, platinum, iridium oxide, silver/silver chloride and other metal or metal compound films

As another improvement of the present invention, there is a voltage follower with enhanced input impedance on the signal processing circuit module, the signal processing circuit module and the electrode body are connected with adhesive glue, and the signal is connected with the voltage follower on the circuit module. The side away from the main body of the electrode is encapsulated with a thermally conductive insulating film layer of resin or insulating varnish. The voltage follower circuit on the signal processing circuit module is welded on a flexible or hard substrate, and there are three wires on it, which are respectively connected to the positive and negative poles of the power supply and the output signal

One side of the electrode body has a hole for injecting liquid electrolyte, and the other side has a wire or conductive silver glue to form a path between the conductive metal film on the electrode surface and the signal processing circuit module.

The electrodes are mounted on an ultra-thin Velcro or self-adhesive patch, which can be freely combined with any wearable product

Compared with the prior art, the moisture-retaining microneedle matrix array surface bioelectric electrode distributes solid or hollow microneedles and hollow micropores on the upper surface of the electrode body, which can infiltrate the liquid electrolyte stored in the cavity of the electrode body into the electrode Between it and the skin, it can play a moisturizing role and effectively improve the stability of bioelectrical signal collection. A signal processing circuit module is connected to the lower surface of the electrode body, and the voltage follower on the signal processing circuit module can increase the input impedance. Use ultra-thin velcro or self-adhesive patch on the bottom of the electrode to ensure that the bioelectric electrode on the surface of the wet microneedle matrix array can be freely combined with wearable products, and can collect the required physiological signals, which has great convenience . At the same time, the bioelectric electrode on the surface of the wet microneedle matrix array can be reused. Compared with the disposable Ag/Agcl electrode with conductive paste, which is discarded after one use, the electrode has a higher utilization rate and is more environmentally friendly.

Description of drawings

Below in conjunction with accompanying drawing and specific embodiment the present invention will be described in further detail:

Fig. 1 is the structural representation of an embodiment of the bioelectric electrode on the surface of the moisturizing microneedle matrix array of the present invention;

Fig. 2 is a top view structure schematic diagram of an embodiment of the bioelectric electrode on the surface of the moisture-retaining microneedle matrix array of the present invention;

Fig. 3 is a structural schematic diagram of another embodiment of the bioelectric electrode on the surface of the moisture-retaining microneedle matrix array of the present invention;

Fig. 4 is a top view structure schematic diagram of another embodiment of the bioelectric electrode on the surface of the moisture-retaining microneedle matrix array of the present invention;

Fig. 5 is a schematic structural view of the signal processing module in an embodiment of the bioelectric electrode on the surface of the moisturizing microneedle matrix array of the present invention;

Fig. 6 is a working principle diagram of a voltage follower in an embodiment of the bioelectric electrode on the surface of the moisturizing microneedle matrix array of the present invention;

Detailed ways

The present invention is described in detail below in conjunction with embodiment and accompanying drawing thereof, but the present invention is not limited by embodiment:

A wet microneedle matrix array surface bioelectric electrode of the present invention (see Figures 1-4), including an electrode body 1, a signal processing module circuit block 2, a thermally conductive insulating film layer 3 and an ultra-thin Velcro or self-adhesive film 4 four parts. There is a cavity 5 inside the electrode body, the cavity 5 is used to store liquid electrolyte, solid or hollow arrays of microneedles 6 and micropores 7 are arranged on the upper surface of the electrode body, and the liquid electrolyte in the cavity 5 can pass through the hollow The array of microneedles 6 and the array of micropores 7 penetrate between the skin and the electrodes. There is a conductive metal film 8 on the upper surface of the electrode body 1 and the surface of the microneedle 6, and the signal processing circuit module 2 is on the back of the electrode body. On the adhesive film 4, the voltage follower circuit 12 on the signal processing circuit module 2 is welded on a flexible or hard substrate, and the wires 14, 15 and 16 are the positive and negative connectors of the power supply and the output signal connectors respectively. There is a hole 10 for injecting liquid electrolyte on the left side of the electrode, and a wire or conductive silver glue 9 connecting the conductive metal film 8 on the electrode surface with the signal processing circuit module 2 on the right side of the electrode.

In this embodiment, the shape of the electrode main body 1 is a cylinder or an ellipsoid, and 3D printing or model casting is adopted, and the materials for 3D printing are selected from photosensitive resin, PLA, ABS resin and the like.

A surface bioelectric electrode of a moisturizing microneedle matrix array of the present invention is divided into two types: a microneedle with a solid body and a microneedle with a hollow body. The structure of the surface bioelectric electrode with a microneedle matrix array with a solid body is shown in Figure 1. The electrolyte can only penetrate between the skin and the electrode through the hollow micropore 7; the surface bioelectric electrode structure of the moisturizing microneedle matrix array with hollow microneedles is shown in Figure 3, and the liquid electrolyte can pass through the hollow microneedle 6 and the micropore 7 Penetrating into the gap between the skin and the electrode, the electrodes of both structures can play a moisturizing role and improve the stability of bioelectrical signals.

A top view of the moisturizing microneedle matrix array surface bioelectric electrode with solid microneedles of the present invention is shown in Figure 2, and the moisturizing microneedle matrix array surface bioelectric electrode with hollow microneedles As shown in Figure 4, the upper surface of the electrode body 1 is distributed with solid or hollow microneedle 6 arrays and microhole 7 arrays, wherein the number of microholes is 4-64, and the number of microneedles is 4-64. The microneedle is solid or hollow, the height of the microneedle is 150 μm to 500 μm, the diameter of the microneedle is 100 μm to 500 μm, the diameter of the hollow micropore is 50 μm to 100 μm, and the tip of the microneedle is tapered or semicircular.

In this embodiment, there is a conductive metal film 8 on the surface of the electrode body 1 and the microneedle 5 array, and the conductive metal film 8 is prepared by methods such as electroless plating, electrochemical deposition, vacuum evaporation or magnetron sputtering. , the metal and metal compound on its surface can be silver, gold, platinum, iridium oxide, silver/silver chloride and other metal or metal compound films.

In this embodiment, the bottom of the electrode uses ultra-thin Velcro or self-adhesive film 4 to ensure that the bioelectric electrode on the surface of the moisturizing microneedle matrix array can be freely combined with the wearable product, and the required physiological signals can be collected. Great convenience.

The structure distribution of the signal processing circuit module 2 of the bioelectric electrode on the surface of a moisturizing microneedle matrix array of the present invention is shown in Figure 5. On the signal processing circuit module 2, a voltage follower 12, a wire 13 connected to the positive pole of the power supply, and a connecting wire 13 are distributed on the signal processing circuit module 2. The wire 14 of the negative pole of the power supply and the wire 15 connected to the output voltage. The signal processing circuit module 2 and the electrode body 1 are connected with adhesive glue, and the voltage follower 12 on the signal processing circuit module 2 is packaged with a thermally conductive insulating film layer 3 of resin or insulating varnish on the side away from the electrode body 1 . The working principle of the voltage follower 12 on the signal processing circuit module 2 of the surface bioelectric electrode of a moisturizing microneedle matrix array of the present invention is shown in Figure 6. The inside of the voltage follower 12 includes a power decoupling capacitor C and a current limiting resistor. R1, resistor R2, power supply voltage VCC and output voltage Vo are connected to the electrode main body by using the voltage follower 12 to effectively increase the input impedance of the electrode.

Claims (8)

1. A moisturizing microneedle matrix array surface bioelectric electrode, the moisturizing microneedle matrix array surface bioelectric electrode comprises an electrode body (1), a signal processing circuit module (2), a thermally conductive insulating film layer (3) and an ultra-thin magic Paste or self-adhesive film (4) four parts, in which there is a cavity (5) inside the electrode body, solid or hollow arrays of microneedles (6) and microholes (7) are arranged on the upper surface of the electrode body. There is a conductive metal film (8) on the surface of the electrode body (1) and the microneedle (6), and a signal processing circuit module (2) is located on the back of the electrode body, and the signal processing circuit module (2) is encapsulated by a thermally conductive insulating film layer (3) and Paste on an ultra-thin velcro or self-adhesive film (4), the voltage follower (12) on the signal processing circuit module (2) is welded on a flexible or hard substrate, and the first wire (13) is connected to the positive pole of the power supply , the second wire (14) is connected to the negative pole of the power supply, and the third wire (15) is connected to the output voltage. 2. Moisturizing microneedle matrix array surface bioelectric electrode according to claim 1, is characterized in that: electrode main body (1) shape is cylinder or ellipsoid structure, and its manufacturing method is 3D printing or model casting method, 3D printing The material used is photosensitive resin, PLA or ABS resin. 3. The moisturizing microneedle matrix array surface bioelectric electrode according to claim 1, characterized in that: the upper surface of the electrode body (1) is distributed with solid or hollow microneedle (6) arrays and micropore (7) arrays, The number of microholes is 4-64, the number of microneedles is 4-64, the microneedles are solid or hollow, the height of the microneedles is 150 μm to 500 μm, the diameter of the microneedles is 100 μm to 500 μm, and the hollow micropores The aperture of the microneedle is between 50 μm and 100 μm, and the tip of the microneedle is conical or semicircular. 4. Moisturizing microneedle matrix array surface bioelectric electrode according to claim 1, is characterized in that: described electrode is hollow, contains cavity (5) inside electrode main body (1), can store liquid electrolyte, liquid Electrolytes are able to penetrate between the electrodes and the skin through hollow microneedles or pores. 5. moisturizing microneedle matrix array surface bioelectric electrode according to claim 1, is characterized in that: the voltage follower (12) that strengthens input impedance is arranged on signal processing circuit module (2), signal processing circuit module (2) ) and the electrode body (1) are connected with adhesive glue, and the voltage follower (12) on the signal processing circuit module (2) adopts a thermally conductive insulating film of resin or insulating varnish on the side away from the electrode body (1) Layer (3) encapsulation. 6. The moisturizing microneedle matrix array surface bioelectric electrode according to claim 1, characterized in that: the electrode is mounted on an ultra-thin Velcro or self-adhesive film (4), and can be freely attached to any wearable product combined. 7. moisturizing microneedle matrix array surface bioelectric electrode according to claim 1, is characterized in that: the surface of electrode main body (1) and microneedle (6) array has conductive metal film (8), and conductive metal film (8 ) is prepared by electroless plating, electrochemical deposition, vacuum evaporation or magnetron sputtering, and its surface is a thin film of metal or metal compound. 8. The moisturizing microneedle matrix array surface bioelectric electrode according to claim 1, characterized in that: there are holes (10) for injecting liquid electrolyte on one side of the electrode body (1), and there are wires or conductive electrodes on the other side. The silver glue (9) forms a path between the conductive metal film (8) on the electrode surface and the signal processing circuit module (2).