CN114764185B - Waste liquid pool with clamping groove mounting mode - Google Patents
Waste liquid pool with clamping groove mounting mode Download PDFInfo
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- CN114764185B CN114764185B CN202110504727.3A CN202110504727A CN114764185B CN 114764185 B CN114764185 B CN 114764185B CN 202110504727 A CN202110504727 A CN 202110504727A CN 114764185 B CN114764185 B CN 114764185B
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- space
- waste liquid
- boss
- upper plane
- side plate
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- 239000007788 liquid Substances 0.000 title claims abstract description 72
- 239000002699 waste material Substances 0.000 title claims abstract description 34
- 239000000758 substrate Substances 0.000 claims abstract description 14
- 238000009434 installation Methods 0.000 claims description 11
- 241000826860 Trapezium Species 0.000 claims 1
- 238000003384 imaging method Methods 0.000 abstract description 33
- 231100000331 toxic Toxicity 0.000 abstract description 6
- 230000002588 toxic effect Effects 0.000 abstract description 6
- 230000009931 harmful effect Effects 0.000 abstract description 4
- 238000000034 method Methods 0.000 description 12
- 230000008569 process Effects 0.000 description 7
- 239000012472 biological sample Substances 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000003287 optical effect Effects 0.000 description 3
- 239000000523 sample Substances 0.000 description 3
- 238000013461 design Methods 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- QURLONWWPWCPIC-UHFFFAOYSA-N 2-(2-aminoethoxy)ethanol;3,6-dichloro-2-methoxybenzoic acid Chemical compound NCCOCCO.COC1=C(Cl)C=CC(Cl)=C1C(O)=O QURLONWWPWCPIC-UHFFFAOYSA-N 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 210000003792 cranial nerve Anatomy 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 238000011900 installation process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000002220 organoid Anatomy 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
-
- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/33—Immersion oils, or microscope systems or objectives for use with immersion fluids
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Microscoopes, Condenser (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The application belongs to the technical field of fluorescent microscope accessories, and particularly relates to a waste liquid tank in a clamping groove mounting mode. A substrate comprising an upper plane and a lower plane; the side plate is fixedly connected to the side edge of the substrate, and the side plate fully surrounds the upper plane to form a first space; the side plate part forms a second space around the lower plane; the first space is internally provided with a liquid containing structure and a connecting structure, and the second space is internally provided with a connecting structure. The application provides a waste liquid pool with a clamping groove mounting mode, which is characterized in that a liquid containing structure is arranged on the upper plane of a substrate to contain imaging liquid sprayed out of an imaging bin, so that the imaging liquid is prevented from polluting a table top, and other harmful effects caused by toxic imaging liquid are avoided.
Description
Technical Field
The application belongs to the technical field of fluorescent microscope accessories, and particularly relates to a waste liquid tank in a clamping groove mounting mode.
Background
With the continuous deep research and exploration of life science, the three-dimensional space information based on biological tissues also enters into deep research, such as cranial nerves, organoids, vascularity and the like.
Methods for processing large-scale biological samples (whole brain and spinal cord of mice, etc.) and three-dimensional microscopic imaging methods are emerging. Researchers carry out transparentization treatment on large-scale biological samples of different types by adopting a plurality of transparentization methods such as CUBIC, CLARITY, uDISCO/iDISCO, PEGASOS and the like, and then rapidly obtain three-dimensional images of complete large-scale biological samples by using a novel microscope such as a light sheet illumination microscope and the like. After the sample is subjected to the transparentization treatment, the sample is fixed on an objective table of a microscope for imaging, imaging liquid can be replaced aiming at samples of different transparentization methods in the imaging process, the condition that the imaging liquid overflows from a container can be avoided in the process of replacing the imaging liquid, the imaging liquid scattered on an operation platform can pollute and corrode the operation platform, and in addition, some imaging liquid is toxic and can cause environmental pollution.
In order to solve the problem, a waste liquid pool which can contain waste liquid, is convenient to detach and clean and can not change the installation position is designed.
Disclosure of Invention
A waste liquid pool with a clamping groove installation mode comprises
A substrate comprising an upper plane and a lower plane;
the side plate is fixedly connected to the side edge of the substrate, and the side plate fully surrounds the upper plane to form a first space; the side plate part forms a second space around the lower plane;
the first space is internally provided with a liquid containing structure and a connecting structure, and the second space is internally provided with a connecting structure.
As a preferable technical scheme, a first boss is arranged in the first space, and the first boss is fixedly connected to the upper plane; the side surface of the first boss, the upper plane and the side surface of the side plate in the upper plane direction form a liquid receiving groove.
As a preferable technical scheme, a protrusion is arranged in the first space, and a threaded hole is formed in the end portion of the protrusion.
As a preferable technical scheme, the cross section pattern of the bulge is one of trapezoid, rectangle, T-shape, convex shape and concave shape.
As a preferable technical scheme, the protrusion is fixedly connected to the first boss, and the height of the protrusion relative to the upper plane is higher than the height of the side plate relative to the upper plane.
As a preferable technical scheme, the side edge of the substrate at least comprises a segment, the side plate is partially arranged around the side edge of the substrate in the lower plane direction, and an opening is arranged at the segment.
As a preferable technical solution, a second boss is disposed in the second space, and the second boss extends from the line segment in a direction opposite to the line segment.
As a preferable technical scheme, a connecting groove is arranged in the boss, and an opening is arranged on the connecting groove at the line segment part.
As a preferred embodiment, the connecting groove is wider near the lower plane and narrower away from the lower plane.
As a preferable technical scheme, the end face of the connecting groove is provided with a threaded hole, the threaded hole is a through hole, and the other end of the threaded hole is arranged on the side plate.
The beneficial effects are that:
the application provides a waste liquid pool with a clamping groove mounting mode, which is characterized in that a liquid containing structure is arranged on the upper plane of a substrate to contain imaging liquid sprayed out of an imaging bin, so that the imaging liquid is prevented from polluting a table top, and other harmful effects caused by toxic imaging liquid are avoided. Meanwhile, a connecting structure is arranged on the upper plane of the base plate and used for installing other fixing accessories. The lower plane is provided with the connecting groove which is open, the movement of the X axis and the Z axis, the rotation of the four degrees of freedom and the rotation of the Y axis are limited, and meanwhile, the end part of the connecting groove is provided with the threaded hole which limits the movement of the Y axis, so that the detachable fixation of the waste liquid pool is realized, the waste liquid pool is convenient to unpick and wash, the positions of the waste liquid pool which is installed again after unpick and wash each time are completely consistent, the incident direction and the angle of the optical system beam are consistent, and the quality of the imaged beam each time is guaranteed.
Drawings
In order to more clearly illustrate the embodiments of the application or the technical solutions in the prior art, the drawings that are required in the embodiments or the description of the prior art will be briefly described, it being obvious that the drawings in the following description are only some embodiments of the application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
The drawings of the embodiments of the present disclosure relate only to the structures related to the embodiments of the present disclosure, and other structures may refer to the general design. In the drawings for describing embodiments of the present disclosure, the thickness of layers or regions is exaggerated or reduced for clarity, i.e., the drawings are not drawn to actual scale.
FIG. 1 is a schematic view of the upper plane perspective structure of a waste liquid tank in a clamping groove installation mode;
FIG. 2 is a schematic view of a lower planar perspective structure;
FIG. 3 is a schematic cross-sectional view;
the device comprises an upper plane 11, a lower plane 12, a line segment 13, a side plate 2, a first boss 3, a liquid receiving groove 4, a protrusion 5, a first threaded hole 6, a second boss 7, a connecting groove 8 and a second threaded hole 9.
Detailed Description
The disclosure of the present application will be further understood in conjunction with the following detailed description of the preferred embodiments of the application, including examples.
When describing embodiments of the present application, the use of "preferred," "more preferred," etc. refers to embodiments of the present application that may provide certain benefits in some instances. However, other embodiments may be preferred under the same or other circumstances. In addition, the recitation of one or more preferred embodiments does not imply that other embodiments are not useful, nor is it intended to exclude other embodiments from the scope of the application.
In this document, relational terms such as first, second, and the like may be used solely to distinguish one entity from another entity without necessarily requiring or implying any actual such relationship or order between such entities. Moreover, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a component, apparatus, or device that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such exclusion, apparatus, or device.
When a component, element, or layer is referred to as being "on," "coupled to," "connected to," or "coupled to" another element, or layer, it can be directly on, coupled to, connected to, or coupled to the other component, element, or layer, or intervening elements or layers may be present. In contrast, when an element is referred to as being "directly on," "directly coupled to," "directly connected to," or "directly coupled to" another element or layer, there may be no intervening elements or layers present. Other words used to describe the relationship between elements should be interpreted in a similar fashion (e.g., "between … …" and "directly between … …", "adjacent" and "directly adjacent", etc.).
A waste liquid tank according to a clamping groove installation mode shown in figures 1-3 comprises
A substrate comprising an upper plane 11 and a lower plane 12;
the side plate 2 is fixedly connected to the side edge of the substrate, and the side plate 2 entirely surrounds the upper plane 11 to form a first space; the side plate 2 partially surrounds the lower plane 12 to form a second space;
the first space is internally provided with a liquid containing structure and a connecting structure, and the second space is internally provided with a connecting structure.
The liquid containing structure in the first space may be any structure capable of containing imaging liquid, and in this embodiment, the liquid receiving tank 4 is preferred;
the connecting structure in the first space may be any structure capable of realizing a connecting function, and in this embodiment, it is preferable that the protrusion 5 and the first threaded hole 6 are formed;
the connection structure in the second space may be any structure capable of realizing a connection function, and in this embodiment, it is preferable that the connection groove 8 and the second screw hole 9 are formed.
A first boss 3 is arranged in the first space, and the first boss 3 is fixedly connected to the upper plane 11; the side surface of the first boss 3, the upper plane 11 and the side surface of the side plate 2 in the direction of the upper plane 11 form a liquid receiving groove 4.
By arranging the liquid receiving tank 4, the imaging liquid sprayed out of the imaging bin is contained, the imaging liquid is prevented from polluting the table top, and other harmful effects caused by toxic imaging liquid are avoided.
A protrusion 5 is arranged in the first space, and a first threaded hole 6 is formed in the end portion of the protrusion 5.
The cross section graph of the bulge 5 is one of trapezoid, rectangle, T-shape, convex shape and concave shape.
The bulge 5 and the first threaded hole 6 are used for connecting other fixed parts, so that the matching of the waste liquid pool and other parts is realized, and the applicability of the waste liquid pool is enhanced.
The protrusion 5 is fixedly connected to the first boss 3, and the height of the protrusion 5 relative to the upper plane 11 is higher than the height of the side plate 2 relative to the upper plane 11.
The bulge 5 is higher than the side plate 2, so that the connection part of the waste liquid tank and other parts is higher than the liquid receiving tank 4, and the imaging liquid in the liquid receiving tank 4 is prevented from polluting other parts matched with the waste liquid tank.
The side edge of the substrate at least comprises a segment 13, the side plate 2 is partially arranged around the side edge of the substrate in the direction of the lower plane 12, and an opening is partially arranged on the segment 13.
The purpose of setting the line segment 13 is to enable the side surface of the waste liquid pool to be provided with at least one plane for matching and aligning with other parts, so that the waste liquid pool is guaranteed to be positioned at the same position after being detached and installed each time, the incident direction and the angle of the optical system beam are guaranteed to be consistent, and the quality of the imaged beam each time is guaranteed.
A second boss 7 is disposed in the second space, and the second boss 7 extends from the line segment 13 in a direction opposite to the line segment 13.
The second boss 7 is provided to reduce the material as much as possible at unnecessary parts, so that the weight of the waste liquid pool is reduced as much as possible under the premise of ensuring stable functions and stable structures, the disassembly and assembly difficulty is reduced, and the loads of other parts in an application scene are reduced.
A connecting groove 8 is arranged in the second boss 7, and an opening is arranged on the connecting groove 8 at the line segment 13.
The purpose of the opening is to open the port of the connecting groove 8, so that the waste liquid pool and the fixing process are in a translational process, the connecting groove 8 is slowly sleeved on the protruding part below, and the stable and accurate installation process is ensured.
The connecting groove 8 is wider near the lower plane 12 and narrower away from the lower plane 12.
The shape of the connecting groove 8 can enable the connection and coordination of the connecting groove 8 to simultaneously limit the movement and rotation of the X axis and the Z axis and one rotation degree of freedom of the Y axis, so that more fixed parts are avoided, the number of parts is reduced, and the assembly process is simplified.
The end face of the connecting groove 8 is provided with a second threaded hole 9, the second threaded hole 9 is a through hole, and the other end of the second threaded hole 9 is arranged on the side plate 2.
The second threaded hole 9 is used for limiting the automatic freedom degree of the Y axis, so that the waste liquid tank can be completely fixed.
Working principle: the application provides a waste liquid pool with a clamping groove mounting mode, which is used in a fluorescent microscope for biological tissue transparentization three-dimensional space information acquisition experiment; in view of the sample test that can carry out different transparentization methods in the experimental process, to ensure that imaging effect is good, just must change corresponding imaging liquid at every turn, this just needs to guarantee that imaging storehouse is stable at every turn's in-process of changing, but the unavoidable hand can shake, can spill imaging liquid. The sprayed imaging liquid can pollute the experiment table surface, and is more troublesome for cleaning some toxic imaging liquids. In addition, each removal of the waste reservoir changes the position of each installation, resulting in a change in the direction of the system beam after it passes through the imaging bin slide. This just needs to design a section waste liquid pond, and convenient dismantlement washs, and the installation direction is the same at every turn.
According to the waste liquid pool with the clamping groove installation mode, the liquid receiving groove 4 is arranged to contain the imaging liquid sprayed out of the imaging bin, so that the imaging liquid is prevented from polluting a table top, and other harmful effects caused by toxic imaging liquid are avoided. The purpose of setting the line segment 13 is to enable the side surface of the waste liquid pool to be provided with at least one plane for matching and aligning with other parts, so that the waste liquid pool is guaranteed to be positioned at the same position after being detached and installed each time, the incident direction and the angle of the optical system beam are guaranteed to be consistent, and the quality of the imaged beam each time is guaranteed. The connecting grooves 8 are arranged in a shape limiting manner, so that the connecting grooves 8 are connected and matched, the movement and the rotation of the X axis and the Z axis are limited, and the rotation of the Y axis is limited, so that more fixed parts are avoided, the number of the parts is reduced, and the assembly process is simplified.
Finally, it should be noted that the above description is only for illustrating the technical solution of the present application, and not for limiting the scope of the present application, and that the simple modification and equivalent substitution of the technical solution of the present application can be made by those skilled in the art without departing from the spirit and scope of the technical solution of the present application.
Claims (5)
1. A draw-in groove mounting means's waste liquid pond, its characterized in that includes:
a substrate comprising an upper plane (11) and a lower plane (12);
the side plates (2) are fixedly connected to the side edges of the substrate, and the side plates (2) fully surround the upper plane (11) to form a first space; -said side plate (2) partly surrounding said lower plane (12) forming a second space;
a liquid containing structure and a connecting structure are arranged in the first space, and a connecting structure is arranged in the second space;
a first boss (3) is arranged in the first space, and the first boss (3) is fixedly connected to the upper plane (11); the side surface of the first boss (3), the upper plane (11) and the side surface of the side plate (2) in the direction of the upper plane (11) form a liquid receiving groove (4);
the side edge of the base plate at least comprises a section of line segment (13), the side plate (2) is arranged around the side edge of the base plate in the direction of the lower plane (12), and an opening is arranged on the section of the line segment (13);
a second boss (7) is arranged in the second space, and the second boss (7) extends from the line segment (13) to a direction opposite to the line segment (13);
a connecting groove (8) is formed in the second boss (7), and an opening is formed in the connecting groove (8) at the part of the line segment (13);
the connecting groove (8) is wider near the lower plane (12) and narrower away from the lower plane (12).
2. The waste liquid pool in the clamping groove installation mode according to claim 1, wherein a protrusion (5) is arranged in the first space, and a first threaded hole (6) is formed in the end portion of the protrusion (5).
3. The waste liquid pool with the card slot installation mode according to claim 2, wherein the cross section pattern of the bulge (5) is one of trapezium, rectangle, T shape, convex shape and concave shape.
4. A card slot installation waste liquid pool as claimed in claim 2 or 3, wherein the projection (5) is fixedly connected to the first boss (3), and the height of the projection (5) relative to the upper plane (11) is higher than the height of the side plate (2) relative to the upper plane (11).
5. The waste liquid pool in the clamping groove installation mode according to claim 1, wherein a second threaded hole (9) is formed in the end face of the connecting groove (8), the second threaded hole (9) is a through hole, and the other end of the second threaded hole (9) is arranged on the side plate (2).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110504727.3A CN114764185B (en) | 2021-05-10 | 2021-05-10 | Waste liquid pool with clamping groove mounting mode |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110504727.3A CN114764185B (en) | 2021-05-10 | 2021-05-10 | Waste liquid pool with clamping groove mounting mode |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114764185A CN114764185A (en) | 2022-07-19 |
| CN114764185B true CN114764185B (en) | 2023-12-15 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202110504727.3A Active CN114764185B (en) | 2021-05-10 | 2021-05-10 | Waste liquid pool with clamping groove mounting mode |
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| Country | Link |
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| CN (1) | CN114764185B (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201344193A (en) * | 2012-04-24 | 2013-11-01 | Ind Tech Res Inst | Immunoassay test apparatus |
| JP2014239675A (en) * | 2013-03-29 | 2014-12-25 | 大日本印刷株式会社 | Structure, micro passage device, and method for using structure |
| CN110068921A (en) * | 2013-10-25 | 2019-07-30 | 牛津大学科技创新有限公司 | Compact microscope |
| CN110743210A (en) * | 2019-10-29 | 2020-02-04 | 孟红娜 | Environment-friendly new energy automobile battery production waste liquid recovery device |
| CN212686275U (en) * | 2020-06-27 | 2021-03-12 | 周娜 | Gold ore deposit chemical examination is with detection reagent storage device |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10871499B2 (en) * | 2017-09-20 | 2020-12-22 | Seiko Epson Corporation | Reagent cartridge, reagent cartridge set, and pathological specimen preparation device |
-
2021
- 2021-05-10 CN CN202110504727.3A patent/CN114764185B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201344193A (en) * | 2012-04-24 | 2013-11-01 | Ind Tech Res Inst | Immunoassay test apparatus |
| JP2014239675A (en) * | 2013-03-29 | 2014-12-25 | 大日本印刷株式会社 | Structure, micro passage device, and method for using structure |
| CN110068921A (en) * | 2013-10-25 | 2019-07-30 | 牛津大学科技创新有限公司 | Compact microscope |
| CN110743210A (en) * | 2019-10-29 | 2020-02-04 | 孟红娜 | Environment-friendly new energy automobile battery production waste liquid recovery device |
| CN212686275U (en) * | 2020-06-27 | 2021-03-12 | 周娜 | Gold ore deposit chemical examination is with detection reagent storage device |
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| Publication number | Publication date |
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| CN114764185A (en) | 2022-07-19 |
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