CN114748645B

CN114748645B - Ferritin-based research and development system for universal influenza vaccine

Info

Publication number: CN114748645B
Application number: CN202210321531.5A
Authority: CN
Inventors: 安有才; 王帅; 张玉辉; 贾春玉; 冷文娜; 陈晓芬
Original assignee: Jiangsu Zhonghui Yuantong Biotechnology Co ltd
Current assignee: Jiangsu Zhonghui Yuantong Biotechnology Co ltd
Priority date: 2022-03-25
Filing date: 2022-03-25
Publication date: 2023-06-06
Anticipated expiration: 2042-03-25
Also published as: CN114748645A

Abstract

The invention relates to the technical field of biological medicine, in particular to a universal influenza vaccine development system based on ferritin. The experimental mouse capturing component is located at one end of the experimental development component, the rear transmission component is located at one end of the experimental mouse capturing component, the experimental development component comprises an experimental mouse incubator, an external pipeline, an observation window, a clamping fault, an attracting pipeline, a connecting pipe, a mouse food placing frame, an odor emission plate and a reaction recording box, wherein the external pipeline penetrates through one middle side of the experimental mouse incubator, through the arrangement of the experimental mouse capturing component, the feeding experimental mouse can be limited in position through structures such as a shrinkage adhesion plate in the feeding process of the experimental mouse, so that the experimental mouse moves in a specified range, and then the experimental mouse can be quickly subjected to subcutaneous injection of influenza vaccine through the controllable groove and the reversible lifting cover, so that the influenza vaccine in research and development can be injected into the body of the experimental mouse under the non-tension atmosphere of the experimental mouse.

Description

Ferritin-based research and development system for universal influenza vaccine

Technical Field

The invention relates to the technical field of biological medicine, in particular to a developing system for a universal influenza vaccine based on ferritin.

Background

Influenza vaccine is used to prevent influenza caused by influenza virus, and is suitable for any healthy person possibly infected with influenza virus, and is inoculated once before epidemic season each year, and immunity can last for one year. Influenza vaccines are one of the main measures for preventing and controlling influenza. Because the HA and NA antigens of the influenza virus are easy to generate antigen drift, the influenza virus is easy to generate variation, and great difficulty is brought to the prediction of annual influenza epidemic strains and the development of influenza vaccines. Thus, the development and preparation of universal influenza vaccines with broad-spectrum resistance that are effective against a variety of different epidemic strains is particularly urgent. The ferritin is taken as a spherical protein which is widely existing in organisms and can be self-assembled, the distance between the amino ends of every two adjacent subunits on the surface is about 4.5-7.5nm, the ferritin is suitable for loading antigens on the outer surface, and the ferritin is further suitable for being taken as a carrier for researching and developing influenza vaccines.

The current process of developing influenza vaccine based on ferritin comprises experimental steps, the experimental steps are that the influenza vaccine is injected into an experimental mouse in the continuously developed influenza vaccine, the reaction of the experimental mouse is observed so as to analyze the drug property of the influenza vaccine, and the experimental mouse is specially cultured in the laboratory, so that when the influenza vaccine is injected into the experimental mouse, medical staff can choose to directly take the experimental mouse to inject the influenza vaccine subcutaneously, and the direct taking mode can lead to the great tension or timidity of the experimental mouse before the influenza vaccine is injected, and further, compared with the normal reaction, the reaction of the experimental mouse after the influenza vaccine is injected has a difference, the feedback of the drug property result of the influenza vaccine is caused, and errors exist, so that the medical staff can not accurately judge the drug property of the influenza vaccine in development.

Disclosure of Invention

The invention aims to provide a developing system for a universal influenza vaccine based on ferritin, which solves the problems in the process.

In order to achieve the above purpose, the present invention provides the following technical solutions: the utility model provides a general influenza research and development system for vaccine based on ferritin, experiment mouse catches one end that subassembly is located experiment research and development subassembly, and wherein rear drive assembly is located experiment mouse and catches one end of subassembly, experiment research and development subassembly is including experiment mouse incubator, external pipeline, observation window, screens fault, lure pipeline, connecting pipe, the frame is placed to the rat food, smell gives off board and reaction record case, and wherein external pipeline runs through the one end medial side of experiment mouse incubator and arranges, the upper end medial side at external pipeline is arranged to the observation window, and wherein screens fault is seted up at the one end of external pipeline, lure the one end of pipeline by screwed connection at external pipeline, wherein the connecting pipe is by screwed connection at the one end of lureing the pipeline, the frame is placed to the rat food embedding is in the one end downside of pipeline, and wherein the smell gives off the board inserts the upper end of placing the frame at the rat food, reaction record case is lured at the one end of connecting pipe by the screw fixation.

Preferably, the external pipeline is connected with the experimental mouse incubator by a screw, wherein transparent glass is placed at the inner end of the observation window, the transparent glass is connected with the external pipeline by glue, the mouse food placing frame is connected with the attracting pipeline by a buckle, the odor emission plate is movably arranged on the mouse food placing frame in a drawing and inserting manner, and a plurality of groups of round holes are formed in the odor emission plate.

Preferably, the one end middle side of laboratory mouse incubator runs through and sets up along to the spout, wherein along to the inner of spout has placed the interior slider, the lower extreme of interior slider sets up welded connection's embedded cardboard, and wherein embedded cardboard is located the inside of screens layer, the one end of interior slider sets up screw connection's pullable pole, and wherein the one end of pullable pole sets up screw connection's location snap ring, laboratory mouse incubator upper end one side sets up screw connection's access guide arm, and wherein access guide arm lower extreme bilateral symmetry sets up buckle connection's elasticity bayonet catch lever, the one end of elasticity bayonet lever sets up integrated into one piece's locking piece.

Preferably, the controllable groove is symmetrically arranged at one end of the attracting pipeline, the turnover lifting cover which is movably connected is symmetrically arranged at two sides of the upper end of the attracting pipeline, the adjusting through groove is arranged at one end of the attracting pipeline in a penetrating mode, a supporting rod which is connected with a buckle is arranged at one side of the upper end of the attracting pipeline, and a sleeving frame which is connected with a screw is arranged at one end of the supporting rod.

Preferably, the laboratory mouse catches subassembly is including shrink laminating board, concave-convex plate, linkage push rod, normal position restoring rod, dislocation clamp plate, afterbody bull stick, outside extension rod and circle slider, wherein the one end at shrink laminating board is fixed to the concave-convex plate, the linkage push rod is by screw connection in upper end one side of shrink laminating board, and wherein normal position restoring rod overlaps on the linkage push rod, dislocation clamp plate welded connection is in the upper end of linkage push rod, afterbody bull stick swing joint is in the one end middle side of shrink laminating board, and wherein outside extension rod swing joint is in the upper end one side of afterbody bull stick, the upper end at outside extension rod is fixed by the buckle to the round slider.

Preferably, the shrink laminating board is evenly located the inside of attracting the pipeline, wherein is integrated into one piece's structure between shrink laminating board and the concave-convex plate, the linkage push rod runs through the one end of attracting the pipeline and arranges, and wherein the normal position resumes the pole and is located the outer end of shrink laminating board, outside extension rod runs through in proper order and adjusts logical groove and cup joints the frame and arrange.

Preferably, the other end of shrink laminating board sets up swing joint's neck and keeps out the board, and wherein neck keeps out board one end and sets up integrated into one piece's anticreep dog, the one end that neck keeps out the board runs through and sets up the removal spout, and wherein the inner of removal spout runs through and has arranged the controllable pole, the controllable pole runs through and lures the pipeline arrangement, and wherein the controllable pole lower extreme sets up buckle connection's interior roof, the cover has welded connection's a run through drum on the controllable pole, run through the upper end of drum and run through and have arranged the upper and lower transfer pole that the pivot is connected, wherein go up down and lure and adopt the spiro union to be connected between the pipeline.

Preferably, the rear transmission assembly comprises a transmission toothed ring, branch rods, a cover baffle, a connecting rod, a surrounding ring and an inner extrusion block, wherein the branch rods are uniformly welded at one end of the transmission toothed ring, the cover baffle is welded at the other end of the branch rods, the connecting rod is uniformly connected at one end of the transmission toothed ring by screws, the surrounding ring is welded at one end of the plurality of groups of connecting rods, the inner extrusion block is uniformly fixed at the inner end of the surrounding ring, the transmission toothed ring is sleeved on an attracting pipeline, and the transmission toothed ring is connected with the attracting pipeline by a rotating shaft.

Compared with the prior art, the invention has the beneficial effects that:

1. through the arrangement of the invention, the laboratory mice can be attracted into the attracting pipeline in advance in a food attracting way, the laboratory mice are not required to be directly controlled by hands of medical staff, the medical staff is convenient to carry out subcutaneous injection of influenza vaccine on the laboratory mice through the pipeline, meanwhile, the laboratory mice cannot be overstressed and timidized in the process of injecting the influenza vaccine, and the numerical value of the laboratory mice in the research and development fed back by the laboratory mice is most accurate, so that the follow-up research and development of the influenza vaccine by the medical staff is facilitated;

2. through the arrangement of the invention, the feeding experimental mouse can be subjected to position limitation by contracting the structures such as the sticking board and the like in the feeding process of the experimental mouse, so that the experimental mouse moves in a specified range, and then the influenza vaccine can be quickly injected into the body of the experimental mouse through the controllable groove and the reversible lifting cover, so that the influenza vaccine in research and development can be injected into the body of the experimental mouse under the non-tension atmosphere of the experimental mouse.

Drawings

FIG. 1 is a schematic perspective view of the present invention;

FIG. 2 is a schematic diagram of a half-cut perspective view of the laboratory mouse incubator of the present invention;

fig. 3 is a schematic perspective view of the attracting pipeline of the present invention;

FIG. 4 is a right side view of the attracting pipeline of the present invention;

fig. 5 is a schematic perspective view of the attracting pipeline of the present invention in semi-section;

FIG. 6 is a schematic drawing showing a front view of the attracting pipeline of the present invention in semi-section;

FIG. 7 is a schematic front view of a shrink-fit board according to the present invention;

FIG. 8 is a perspective view of a drive ring gear of the present invention;

FIG. 9 is an enlarged schematic view of the invention at A in FIG. 2;

fig. 10 is an enlarged schematic view of the invention at B in fig. 5.

In the figure: the experimental mouse incubator 1, the edge slide groove 101, the inner slide block 102, the embedded clamping plate 103, the pullable rod 104, the positioning clamping ring 105, the access guide rod 106, the elastic clamping rod 107, the locking block 108, the external pipeline 11, the observation window 12, the clamping fault 13, the attracting pipeline 14, the controllable groove 1401, the reversible lifting cover 1402, the adjusting through groove 1403, the supporting rod 1404, the sleeving frame 1405, the connecting pipe 15, the mouse food placing frame 16, the odor emission plate 17, the reaction recording box 18, the shrinkage adhesion plate 2, the neck adhesion plate 201, the anti-falling stop block 202, the moving slide groove 203, the controllable rod 204, the inner top plate 205, the penetrating cylinder 206, the up-down adjusting rod 207, the concave-convex plate 21, the linkage push rod 22, the in-situ restoring rod 23, the dislocation pressing plate 24, the tail rotary rod 25, the outer extension rod 26, the smooth block 27, the transmission toothed ring 3, the branching rod 31, the covering baffle 32, the receiving connecting rod 33, the encircling circular ring 34 and the inner extrusion block 35.

Detailed Description

Features and exemplary embodiments of various aspects of the invention are described in detail below. In the following detailed description, numerous specific details are set forth in order to provide a thorough understanding of the invention. It will be apparent, however, to one skilled in the art that the present invention may be practiced without some of these specific details. The following description of the embodiments is merely intended to provide a better understanding of the invention by showing examples of the invention. The present invention is in no way limited to any particular configuration and algorithm set forth below, but rather covers any modification, substitution, and improvement of elements, components, and algorithms without departing from the spirit of the invention. In the drawings and the following description, well-known structures and techniques have not been shown in order to avoid unnecessarily obscuring the present invention.

Referring to fig. 1 to 10, the present invention provides a technical solution: including the experiment research and development subassembly that has the experiment mouse function of natural attracting, the experiment mouse catches subassembly that has laminating restriction function and the rear drive subassembly that has synchronous restriction function, the experiment mouse catches the one end that the subassembly was located experiment research and development subassembly, wherein the rear drive subassembly is located the one end that the subassembly was caught to the experiment mouse, experiment research and development subassembly is including experiment mouse incubator 1, external pipeline 11, observation window 12, screens layer 13, lure pipeline 14, connecting pipe 15, the frame 16 is placed to the rat feed, smell gives off board 17 and reaction record case 18, wherein external pipeline 11 runs through the one end medial side of experiment mouse incubator 1 and arranges, observation window 12 arranges the upper end medial side of external pipeline 11, wherein screens layer 13 is seted up at the one end of external pipeline 11, lure pipeline 14 by screwed connection at the one end of external pipeline 11, wherein connecting pipe 15 is by screwed connection at the one end of lured pipeline 14, frame 16 is placed to the rat feed is embedded at the one end downside of connecting pipe 14, wherein smell gives off board 17 inserts the upper end of placing frame 16, reaction record case 18 is by the screw fixation at the one end of 15.

Meanwhile, the mode of attracting the laboratory mice by food is utilized, so that the laboratory mice have stronger appetite and better experiment effect, at the moment, the laboratory mice cannot be overstressed and timidized in the process of injecting the influenza vaccine, the numerical value of the laboratory mice in the research and development fed back by the laboratory mice is most accurate, the laboratory mice completed by injecting the influenza vaccine can enter the reaction recording box 18, medical staff can directly pass through the reaction recording box 18, and the reaction after the influenza vaccine in the research and development is injected to the laboratory mice can be realized.

The connecting pipe 15 is transparent plastic pipe with lure the material that pipeline 14 adopted, be convenient for medical personnel observe the dynamics of laboratory mouse constantly, the material of external pipeline 11 can be metal or plastics simultaneously, through observation window 12, can observe whether the laboratory mouse leaves the inside of external pipeline 11, the work of giving medical personnel is convenient, further the frame 16 is placed to the mouse food and lure the intercommunication between pipeline 14 to the frame 16 is placed to the mouse food and lure the pipeline 14 to adopt the buckle to connect, the medical personnel of being convenient for take the frame 16 is placed to the mouse food, the medical personnel of being convenient for adds the mouse food to the inside of placing frame 16 is placed to the mouse food, realize the lure to the laboratory mouse, insert smell emission board 17 on placing the frame 16 at the same time, can control the food of laboratory mouse, even can directly utilize the smell of mouse food to lure the laboratory mouse, and can not let the laboratory mouse eat.

The external pipeline 11 is connected with the experimental rat incubator 1 by adopting a screw, wherein transparent glass is placed at the inner end of the observation window 12, the transparent glass is connected with the external pipeline 11 by adopting glue, the rat feed placing frame 16 is connected with the attracting pipeline 14 by adopting a buckle, the odor emission plate 17 is movably arranged on the rat feed placing frame 16 in a drawing and inserting way, and a plurality of groups of circular holes are formed in the odor emission plate 17.

The round holes are convenient for the odor of the mice to be emitted.

The middle side of one end of the laboratory mouse incubator 1 is penetrated and is offered along to the spout 101, wherein along to the inner of spout 101 place interior slider 102, the lower extreme of interior slider 102 sets up welded connection's embedded cardboard 103, wherein embedded cardboard 103 is located the inside of screens layer 13, the one end of interior slider 102 sets up screw connection's pullable pole 104, wherein the one end of pullable pole 104 sets up screw connection's location snap ring 105, laboratory mouse incubator 1 upper end one side sets up screw connection's access guide 106, wherein access guide 106 lower extreme bilateral symmetry sets up buckle connection's elasticity bayonet catch 107, the one end of elasticity bayonet catch 107 sets up integrated into one piece's locking piece 108.

Utilize along to spout 101 and interior slider 102, can slide from top to bottom to embedding cardboard 103, the embedding cardboard 103 of being convenient for inserts or leaves the inside of screens fault 13, when needs lure the laboratory mouse, upwards pulling can pull rod 104, make interior slider 102 slide along to spout 101's inside, simultaneously make access guide arm 107 enter into the inside of location snap ring 105, further access guide arm 107 takes place deformation, locking piece 108 can block the lower extreme at location snap ring 105 this moment, and then accomplish the purpose to embedding cardboard 103 position restriction, the laboratory mouse's of being convenient for is eaten to the lure of laboratory mouse, embedding cardboard 103 card is in the inside of screens fault 13 simultaneously, also can prevent that the laboratory mouse that the injection had influenza vaccine from getting back to the inside of laboratory mouse incubator 1.

The controllable grooves 1401 are symmetrically formed in two sides of one end of the attracting pipeline 14, wherein the movable turnover covers 1402 are symmetrically arranged on two sides of the upper end of the attracting pipeline 14, the adjusting through grooves 1403 are formed in one end of the attracting pipeline 14 in a penetrating mode, the supporting rods 1404 are connected in a buckling mode on one side of the upper end of the attracting pipeline 14, and the sleeving frames 1405 are connected through screws on one end of the supporting rods 1404.

The reversible lifting cover 1402 is connected with the attracting pipeline 14 through a rotating shaft, the reversible lifting cover 1402 covers the controllable groove 1401, the reversible lifting cover 14021 is reversed, the controllable groove 1401 can be exposed, at the moment, two sides of the body of the laboratory mouse are exposed, medical staff can conveniently and rapidly pass through the subcutaneous of the laboratory mouse, and injection of influenza vaccine in research and development is completed on the laboratory mouse.

The laboratory mouse catches subassembly is including shrink laminating board 2, the concave-convex plate 21, linkage push rod 22, normal position resume pole 23, dislocation clamp plate 24, afterbody bull stick 25, outside extension pole 26 and round sliding block 27, wherein the concave-convex plate 21 is fixed in the one end of shrink laminating board 2, linkage push rod 22 is by screw connection in the upper end one side of shrink laminating board 2, wherein normal position resume pole 23 cover is on linkage push rod 22, dislocation clamp plate 24 welded connection is in the upper end of linkage push rod 22, afterbody bull stick 25 swing joint is in the one end middle side of shrink laminating board 2, wherein outside extension pole 26 swing joint is in afterbody bull stick 25's upper end one side, round sliding block 27 is fixed in outside extension pole 26's upper end by the buckle.

The shape of shrink laminating board 2 and concave-convex plate 21 can arrange according to the trapezium of laboratory mouse, can embed fixed contactor in the inside of concave-convex plate 21 simultaneously, prevent that concave-convex plate 21 is excessive to the laboratory mouse from excessively restricting, arouse the reaction of laboratory mouse, the shape that dislocation clamp plate 24 arranged is the arc, dislocation clamp plate 24 is located the inside that encircles ring 34 simultaneously, normal position restoring rod 23 can be elasticity, also can be the curved lever that has the elastic rod, normal position restoring rod 23 mainly is responsible for the later stage of linkage push rod 22 and resets, and then realize shrink laminating board 2 and concave-convex plate 21's reset for the health of laboratory mouse can not receive the restriction.

The shrink fitting plate 2 is uniformly located inside the attracting pipeline 14, wherein the shrink fitting plate 2 and the concave-convex plate 21 are of an integrally formed structure, the linkage push rod 22 penetrates through one end of the attracting pipeline 14 to be arranged, the in-situ restoring rod 23 is located at the outer end of the shrink fitting plate 2, and the outer extension rod 26 penetrates through the adjusting through groove 1403 and the sleeving frame 1405 in sequence.

Through shrink adhesion plate 2 and concave-convex plate 21, carry out the position restriction to the experiment mouse body trunk that is eating for the experiment mouse moves in the regulation scope, specifically, when dislocation clamp plate 24 is pressed, linkage push rod 22 is pushed, shrink adhesion plate 2 and concave-convex plate 21 can carry out the laminating slightly to the experiment mouse's body, realize the purpose to experiment mouse position restriction, adopt the torsional spring to be connected between afterbody bull stick 25 and the shrink adhesion plate 2 simultaneously, adopt the torsional spring to be connected between outside extension rod 26 and the afterbody bull stick 25, the position of afterbody bull stick 25 and outside extension rod 26 can change along with the position of shrink adhesion plate 2, afterbody bull stick 25 can restrict the afterbody of experiment mouse simultaneously, prevent that the phenomenon of backing up from appearing in the experiment mouse.

The other end of the shrink laminating plate 2 is provided with a neck retaining plate 201 which is movably connected, wherein one end of the neck retaining plate 201 is provided with an integrally formed anti-drop stop block 202, one end of the neck retaining plate 201 is penetrated and provided with a movable sliding groove 203, the inner end of the movable sliding groove 203 is penetrated and provided with a controllable rod 204, the controllable rod 204 is penetrated and provided with an attracting pipeline 14, the lower end of the controllable rod 204 is provided with an inner top plate 205 which is in snap connection, the controllable rod 204 is sleeved with a penetrating cylinder 206 which is in welded connection, the upper end of the penetrating cylinder 206 is penetrated and provided with an upper and lower adjusting rod 207 which is connected with a rotating shaft, and the upper and lower adjusting rod 207 is in threaded connection with the attracting pipeline 14.

Neck abutment plate 201 and anticreep dog 202 can restrict the neck position of laboratory mouse, can effectually move the laboratory mouse to the front end for the laboratory mouse can normally accomplish the injection flow of influenza vaccine, adopts the torsional spring to connect between neck abutment plate 201 and the shrink adhesion plate 2.

Through the rotation to the vertical adjustment pole 207, can make the controllable pole 204 carry out the up-and-down motion, simultaneously with the help of running through the buffering of drum 206 for the controllable pole 204 can not rotate along with the vertical adjustment pole 207, when the controllable pole 204 upward movement, under the effect of removal spout 203 and interior roof 205, make neck butt plate 201 can upwards perk, consequently can increase the interval between a plurality of neck butt plates 201, so that later carry out the position restriction operation to the neck of laboratory mouse.

The rear transmission assembly comprises a transmission toothed ring 3, a branch rod 31, a cover baffle 32, a receiving connecting rod 33, a surrounding ring 34 and an inner extrusion block 35, wherein the branch rod 31 is uniformly welded at one end of the transmission toothed ring 3, the cover baffle 32 is welded at the other end of the branch rod 31, the receiving connecting rod 33 is uniformly connected at one end of the transmission toothed ring 3 through screws, the surrounding ring 34 is welded at one end of a plurality of groups of receiving connecting rods, the inner extrusion block 35 is uniformly fixed at the inner end of the surrounding ring 34, the transmission toothed ring 3 is sleeved on the attracting pipeline 14, and the transmission toothed ring 3 is connected with the attracting pipeline 14 through a rotating shaft.

The transmission toothed ring 3 can be driven by a gear, a motor for driving the gear to rotate is in signal connection with the contactor, the transmission toothed ring 3 can be driven by a connecting rod 33 to drive a surrounding circular ring 34, so that the inner extrusion block 35 presses down the misplacement pressing plate 24, and the outer extension rod 26 is pressed down by a circular sliding block 27 when the plate 32 is covered.

The different technical features presented in the different embodiments may be combined to advantage. Other variations to the disclosed embodiments can be understood and effected by those skilled in the art in view of the drawings, the description, and the claims. In the claims, the term "comprising" does not exclude other means or steps; the indefinite article "a" does not exclude a plurality; the terms "first," "second," and the like, are used for designating a name and not for indicating any particular order. Any reference signs in the claims shall not be construed as limiting the scope. The functions of the various elements presented in the claims may be implemented by means of a single hardware or software module. The presence of certain features in different dependent claims does not imply that these features cannot be combined to advantage.

Claims

1. The utility model provides a general influenza research and development system for vaccine based on ferritin, includes that experiment research and development subassembly that has natural lure laboratory mouse function, laboratory mouse that has laminating restriction function catch subassembly and have synchronous restriction function's rear drive subassembly, its characterized in that: the experiment mouse catches one end that the subassembly is located experiment research and development subassembly, wherein the rear drive assembly is located the one end that the experiment mouse caught the subassembly, experiment research and development subassembly is including experiment mouse incubator (1), external pipeline (11), observation window (12), screens layer (13), lure pipeline (14), connecting pipe (15), frame (16) are placed to the mouse food, smell gives off board (17) and reaction record case (18) are placed to smell, wherein external pipeline (11) run through the one end middle side arrangement of experiment mouse incubator (1), observation window (12) are arranged in the upper end middle side of external pipeline (11), wherein screens layer (13) are seted up in the one end of external pipeline (11), pipeline (14) are by screwed connection in the one end of external pipeline (11), wherein connecting pipe (15) are by screwed connection in the one end of lure pipeline (14), frame (16) are placed in the one end downside of lure pipeline (14) to the mouse food, wherein smell gives off board (17) and inserts the upper end of frame (16) in the mouse food, reaction record case (18) are by fixed in connecting pipe (15), tail (21), tail (24), tail (25) are caught tail (25), tail (25) are drawn back and are drawn together to the experiment board (25), tail (25) is including the normal position Outside extension rod (26) and round sliding block (27), wherein concave-convex plate (21) are fixed in the one end of shrink adhesion plate (2), linkage push rod (22) are by screw connection in the upper end one side of shrink adhesion plate (2), wherein normal position restoring rod (23) cover is on linkage push rod (22), dislocation clamp plate (24) welded connection is in the upper end of linkage push rod (22), afterbody bull stick (25) swing joint is in the one end middle side of shrink adhesion plate (2), wherein outside extension rod (26) swing joint is in the upper end one side of afterbody bull stick (25), round sliding block (27) are fixed in the upper end of outside extension rod (26) by the buckle, shrink adhesion plate (2) evenly are located the inside of shrink adhesion plate (14), wherein be integrated into one piece's structure between shrink adhesion plate (2) and the (21), one end that lures adhesion plate (22) runs through lured adhesion plate (14) is arranged, wherein normal position restoring rod (23) are located the outer end of adhesion plate (2), outside extension rod (26) are connected with flexible neck (201) in proper order, extension rod (201) are arranged in proper order, neck (201) are connected with flexible neck (201), the neck butt plate is characterized in that one end of the neck butt plate (201) is penetrated and provided with a movable chute (203), the inner end of the movable chute (203) is penetrated and provided with a controllable rod (204), the controllable rod (204) is penetrated and provided with an attracting pipeline (14), the lower end of the controllable rod (204) is provided with an inner top plate (205) connected in a buckling manner, the controllable rod (204) is sleeved with a penetrating cylinder (206) connected in a welding manner, the upper end of the penetrating cylinder (206) is penetrated and provided with an upper and lower adjusting rod (207) connected with a rotating shaft in a penetrating manner, and the upper and lower adjusting rod (207) is connected with the attracting pipeline (14) in a threaded manner.

2. The ferritin-based universal influenza vaccine development system of claim 1, wherein: adopt screw connection between external pipeline (11) and experiment mouse incubator (1), wherein transparent glass is placed to the inner of observation window (12), adopts gluey connection between its transparent glass and the external pipeline (11), adopt the buckle to be connected between frame (16) and the attracting pipeline (14) are placed to the mouse food, and wherein smell gives off board (17) and takes out the activity on frame (16) and insert the arrangement of placing to the mouse food, set up multiunit circular hole on smell gives off board (17).

3. A development system for a ferritin-based universal influenza vaccine according to claim 2, wherein: the one end middle side of laboratory mouse incubator (1) runs through and sets up along to spout (101), wherein along to interior sliding block (102) of spout (101) have been placed, the lower extreme of interior sliding block (102) sets up welded connection's embedded cardboard (103), and wherein embedded cardboard (103) are located the inside of screens fault (13), the one end of interior sliding block (102) sets up screw connection's pulling rod (104), and wherein the one end of pulling rod (104) sets up screw connection's location snap ring (105), laboratory mouse incubator (1) upper end one side sets up screw connection's access guide arm (106), and wherein access guide arm (106) lower extreme bilateral symmetry sets up buckle connection's elasticity bayonet lock (107), the one end of elasticity bayonet lock (107) sets up integrated into one piece's locking piece (108).

4. A development system for a ferritin-based universal influenza vaccine according to claim 2, wherein: the novel multifunctional induction pipe is characterized in that controllable grooves (1401) are symmetrically formed in two sides of one end of the induction pipe (14), movable connection turnover covers (1402) are symmetrically arranged on two sides of the upper end of the induction pipe (14), an adjusting through groove (1403) is formed in one end of the induction pipe (14) in a penetrating mode, a supporting rod (1404) in buckling connection is arranged on one side of the upper end of the induction pipe (14), and a sleeving frame (1405) in screw connection is arranged at one end of the supporting rod (1404).

5. The ferritin-based universal influenza vaccine development system of claim 1, wherein: the rear transmission assembly comprises a transmission toothed ring (3), a branch rod (31), a covering baffle (32), a connecting rod (33), a surrounding circular ring (34) and an inner extrusion block (35), wherein the branch rod (31) is uniformly welded at one end of the transmission toothed ring (3), the covering baffle (32) is welded at the other end of the branch rod (31), the connecting rod (33) is uniformly connected at one end of the transmission toothed ring (3) through screws, the surrounding circular ring (34) is welded at one end of the plurality of groups of connecting rods (33), the inner extrusion block (35) is uniformly fixed at the inner end of the surrounding circular ring (34), the transmission toothed ring (3) is sleeved on an attracting pipeline (14), and the transmission toothed ring (3) is connected with the attracting pipeline (14) through a rotating shaft.