CN114746145B - 用于提供肿瘤治疗场的可植入阵列 - Google Patents

用于提供肿瘤治疗场的可植入阵列

Info

Publication number
CN114746145B
CN114746145B CN202080080428.5A CN202080080428A CN114746145B CN 114746145 B CN114746145 B CN 114746145B CN 202080080428 A CN202080080428 A CN 202080080428A CN 114746145 B CN114746145 B CN 114746145B
Authority
CN
China
Prior art keywords
implantable device
electric field
electrode
electrodes
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202080080428.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN114746145A (zh
Inventor
K·W·卡尔森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novokule Co ltd
Original Assignee
Novokule Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novokule Co ltd filed Critical Novokule Co ltd
Publication of CN114746145A publication Critical patent/CN114746145A/zh
Application granted granted Critical
Publication of CN114746145B publication Critical patent/CN114746145B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36002Cancer treatment, e.g. tumour
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36017External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/05Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526Head electrodes
    • A61N1/0529Electrodes for brain stimulation
    • A61N1/0534Electrodes for deep brain stimulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • A61N1/403Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals for thermotherapy, e.g. hyperthermia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Electrotherapy Devices (AREA)
CN202080080428.5A 2019-11-21 2020-11-19 用于提供肿瘤治疗场的可植入阵列 Active CN114746145B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962938586P 2019-11-21 2019-11-21
US62/938586 2019-11-21
US202063085658P 2020-09-30 2020-09-30
US63/085658 2020-09-30
PCT/US2020/061251 WO2021102120A1 (en) 2019-11-21 2020-11-19 Implantable arrays for providing tumor treating fields

Publications (2)

Publication Number Publication Date
CN114746145A CN114746145A (zh) 2022-07-12
CN114746145B true CN114746145B (zh) 2025-09-12

Family

ID=73646603

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080080428.5A Active CN114746145B (zh) 2019-11-21 2020-11-19 用于提供肿瘤治疗场的可植入阵列

Country Status (5)

Country Link
US (1) US20240299742A1 (https=)
EP (4) EP4061477B1 (https=)
JP (1) JP2023502506A (https=)
CN (1) CN114746145B (https=)
WO (1) WO2021102120A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2023014169A (es) * 2021-06-30 2024-01-10 Novocure Gmbh Sistema de suministro de campos de tratamiento de tumores (ttfields) y de medicion de impedancia.
CN114225215B (zh) * 2021-12-31 2023-05-05 湖南安泰康成生物科技有限公司 电极系统
CN115227977B (zh) * 2022-07-21 2024-01-26 佛山科学技术学院 一种肿瘤电脉冲化学治疗系统
IL321752B1 (en) * 2023-02-06 2026-01-01 Novocure Gmbh Movable transducer array with anisotropic material layer
CN116650838B (zh) * 2023-06-08 2024-10-18 山东大学齐鲁医院 一种脑内植入式电场治疗设备
WO2025068877A1 (en) * 2023-09-29 2025-04-03 Novocure Gmbh Low frequency rf ablation system

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009520509A (ja) * 2005-10-03 2009-05-28 ノヴォキュアー・リミテッド 増殖細胞における電場の効果を増大させるための電場の最適化特性
WO2018207103A1 (en) * 2017-05-08 2018-11-15 Cardio Technology Sp. Z O.O. A system and a method for treating tumors, especially intracranial tumors

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016886A (en) * 1974-11-26 1977-04-12 The United States Of America As Represented By The United States Energy Research And Development Administration Method for localizing heating in tumor tissue
US4346715A (en) * 1978-07-12 1982-08-31 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Hyperthermia heating apparatus
DE19758114C2 (de) * 1997-12-17 2001-08-23 Biotronik Mess & Therapieg Elektrodenanordnung zur Rückenmarkstimulation
US7805201B2 (en) 2000-02-17 2010-09-28 Standen Ltd. Treating a tumor or the like with an electric field
US6868289B2 (en) * 2002-10-02 2005-03-15 Standen Ltd. Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor
US20170050021A1 (en) * 2004-08-20 2017-02-23 Eric Richard Cosman, SR. Random pulsed high frequency therapy
CA2594231C (en) * 2004-12-27 2016-04-19 Standen Ltd. Treating a tumor or the like with electric fields at different orientations
US7455689B2 (en) * 2005-08-25 2008-11-25 Edwards Lifesciences Corporation Four-leaflet stented mitral heart valve
EP2288407A1 (en) * 2008-04-29 2011-03-02 Medtronic, Inc. Therapy program modification
US20140221829A1 (en) * 2013-02-01 2014-08-07 The Texas A&M University System Localized fluorescence excitation in whole body optical imaging
WO2017201625A1 (en) * 2016-05-25 2017-11-30 Samuel Victor Lichtenstein System for treating unwanted tissue
JP6980706B2 (ja) * 2016-06-30 2021-12-15 ノボキュア ゲーエムベーハー 身体への腫瘍治療電場の長手方向伝達用のアレイ
US12403306B2 (en) * 2017-10-23 2025-09-02 Cardiac Pacemakers, Inc. Electric field shaping leads for treatment of cancer
US11338135B2 (en) * 2017-10-23 2022-05-24 Cardiac Pacemakers, Inc. Medical devices for cancer therapy with electric field shaping elements
US11607542B2 (en) * 2019-04-23 2023-03-21 Boston Scientific Scimed, Inc. Electrical stimulation for cancer treatment with internal and external electrodes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009520509A (ja) * 2005-10-03 2009-05-28 ノヴォキュアー・リミテッド 増殖細胞における電場の効果を増大させるための電場の最適化特性
WO2018207103A1 (en) * 2017-05-08 2018-11-15 Cardio Technology Sp. Z O.O. A system and a method for treating tumors, especially intracranial tumors

Also Published As

Publication number Publication date
WO2021102120A1 (en) 2021-05-27
JP2023502506A (ja) 2023-01-24
EP4061477A1 (en) 2022-09-28
EP4061477B1 (en) 2023-09-06
EP4129397A1 (en) 2023-02-08
EP4129397C0 (en) 2024-09-25
CN114746145A (zh) 2022-07-12
EP4129398A1 (en) 2023-02-08
US20240299742A1 (en) 2024-09-12
EP4061477C0 (en) 2023-09-06
EP4134127A1 (en) 2023-02-15
EP4129397B1 (en) 2024-09-25

Similar Documents

Publication Publication Date Title
CN114746145B (zh) 用于提供肿瘤治疗场的可植入阵列
US12059197B2 (en) Blood-brain barrier disruption using reversible or irreversible electroporation
US12173280B2 (en) Methods of reducing adverse effects of non-thermal ablation
CA2892449C (en) Regulating organ and tumor growth rates, function, and development
CN116322890A (zh) 用于提供肿瘤治疗场的可植入阵列
KR20180006365A (ko) 신경전도 확인 및 제한을 위한 시스템 및 디바이스
CN111615371A (zh) 用于肿瘤消融的增强的针阵列及治疗
US20250000569A1 (en) Blood-brain barrier disruption using reversible or irreversible electroporation
JP6749339B2 (ja) 高周波除神経ニードルおよび方法
JP2019534752A (ja) 求心性神経線維を選択的に活性化する為の装置及び方法
JP2020089723A (ja) 神経系構造を選択的かつ可逆的に調節して疼痛知覚を抑制する装置及び方法
US20250228602A1 (en) Methods of reducing adverse effects of non-thermal ablation
WO2013114156A1 (en) Apparatus and method for irradiating biological tissue
US20250352830A1 (en) Simultaneous ultrasonic imaging and low intensity focused ultrasound therapy
WO2016090196A1 (en) Systems and methods for regulating organ and/or tumor growth rates, function, and/or development
US20050288663A1 (en) Method and apparatus for substantial uniform ablation about a bipolar array of electrodes
HK40080408B (en) Implantable arrays for providing tumor treating fields
HK40081209A (en) Apparatus for providing tumor treating fields
HK40080867A (en) Implantable arrays for providing tumor treating fields
HK40080408A (en) Implantable arrays for providing tumor treating fields
HK40073711A (en) Implantable arrays for providing tumor treating fields
HK40073711B (en) Implantable arrays for providing tumor treating fields
US12533532B2 (en) Image-guided pulsed volume focused ultrasound
TW202602515A (zh) 用於腫瘤電場治療之電極貼片

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant