CN114728057A - 用于调节髓系细胞炎性表型的抗cd53组合物和方法及其用途 - Google Patents

用于调节髓系细胞炎性表型的抗cd53组合物和方法及其用途 Download PDF

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CN114728057A
CN114728057A CN202080060640.5A CN202080060640A CN114728057A CN 114728057 A CN114728057 A CN 114728057A CN 202080060640 A CN202080060640 A CN 202080060640A CN 114728057 A CN114728057 A CN 114728057A
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cells
macrophages
cell
myeloid cells
agent
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T·I·诺沃布兰塞瓦
I·费尔德曼
S·L·萨金斯基
J·A·瓦勒
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Viseo Pharmaceutical Co
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Viseo Pharmaceutical Co
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/17—Monocytes; Macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00—Cellular immunotherapy
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CN202080060640.5A 2019-06-27 2020-06-17 用于调节髓系细胞炎性表型的抗cd53组合物和方法及其用途 Pending CN114728057A (zh)

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US201962867602P 2019-06-27 2019-06-27
US62/867602 2019-06-27
PCT/US2020/038116 WO2020263651A1 (en) 2019-06-27 2020-06-17 Anti-cd53 compositions and methods for modulating myeloid cell inflammatory phenotypes and uses thereof

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US (1) US20220251233A1 (https=)
EP (1) EP3990015A4 (https=)
JP (1) JP2022540768A (https=)
KR (1) KR20220042128A (https=)
CN (1) CN114728057A (https=)
AU (1) AU2020304415A1 (https=)
BR (1) BR112021026181A2 (https=)
CA (1) CA3142840A1 (https=)
IL (1) IL289171A (https=)
WO (1) WO2020263651A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116380755A (zh) * 2023-03-20 2023-07-04 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） CD127+PMN-MDSCs在诊断支气管肺发育不良中的应用及诊断试剂盒

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Publication number Priority date Publication date Assignee Title
KR102616360B1 (ko) * 2021-11-09 2023-12-27 재단법인 아산사회복지재단 염증성 근육병증 진단용 바이오마커 조성물
WO2024220870A1 (en) * 2023-04-19 2024-10-24 The University Of Chicago Antibody-targeted enzymatic chemoprotection
CN117816128B (zh) * 2023-12-15 2025-11-25 华南农业大学 一种重金属检测-吸附一体化复合材料及其制备方法与应用
JP7720659B1 (ja) * 2024-11-15 2025-08-08 宜広 磯貝 骨感染症の血漿バイオマーカー

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WO1992001049A2 (en) * 1990-07-13 1992-01-23 The General Hospital Corporation Cd53 cell surface antigen and use thereof
WO2018026819A2 (en) * 2016-08-01 2018-02-08 Novartis Ag Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
WO2019075220A1 (en) * 2017-10-11 2019-04-18 Bioverativ Usa Inc. METHODS FOR INDUCING COMPLEMENT ACTIVITY
US20190153079A1 (en) * 2016-04-04 2019-05-23 Bioverativ Usa Inc. Anti-complement factor bb antibodies and uses thereof
WO2020006385A2 (en) * 2018-06-29 2020-01-02 Verseau Therapeutics, Inc. Compositions and methods for modulating monocyte and macrophage inflammatory phenotypes and immunotherapy uses thereof

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WO2002072861A1 (en) * 2001-03-08 2002-09-19 Incyte Genomics, Inc. Cd53 cell surface antigen
US7674598B2 (en) * 2004-05-21 2010-03-09 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
CN101583722A (zh) * 2006-07-14 2009-11-18 阿维瓦生物科学股份有限公司 从生物学样品检测稀有细胞的方法和组合物
JP7078533B2 (ja) * 2015-10-21 2022-05-31 オーエスイー イムノセラピューティクス 炎症促進性細胞へのマクロファージ分極を改変して癌を治療するための抗ＳＩＲＰａ化合物

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WO1992001049A2 (en) * 1990-07-13 1992-01-23 The General Hospital Corporation Cd53 cell surface antigen and use thereof
US20190153079A1 (en) * 2016-04-04 2019-05-23 Bioverativ Usa Inc. Anti-complement factor bb antibodies and uses thereof
WO2018026819A2 (en) * 2016-08-01 2018-02-08 Novartis Ag Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
WO2019075220A1 (en) * 2017-10-11 2019-04-18 Bioverativ Usa Inc. METHODS FOR INDUCING COMPLEMENT ACTIVITY
WO2020006385A2 (en) * 2018-06-29 2020-01-02 Verseau Therapeutics, Inc. Compositions and methods for modulating monocyte and macrophage inflammatory phenotypes and immunotherapy uses thereof

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IZABELA TODROS-DAWDA，等: "The Tetraspanin CD53 Modulates Responses from Activating NK Cell Receptors, Promoting LFA-1 Activation and Dampening NK Cell Effector Functions", PLOS ONE, vol. 9, no. 5, 15 May 2014 (2014-05-15), pages 1, XP055882103, DOI: 10.1371/journal.pone.0097844 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116380755A (zh) * 2023-03-20 2023-07-04 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） CD127+PMN-MDSCs在诊断支气管肺发育不良中的应用及诊断试剂盒
CN116380755B (zh) * 2023-03-20 2023-11-21 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） CD127+PMN-MDSCs在诊断支气管肺发育不良中的应用及诊断试剂盒

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CA3142840A1 (en) 2020-12-30
JP2022540768A (ja) 2022-09-20
AU2020304415A1 (en) 2022-02-17
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WO2020263651A1 (en) 2020-12-30
US20220251233A1 (en) 2022-08-11

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