CN114720930A - Magnetic resonance imaging method, device and equipment of pulse gating system and storage medium - Google Patents

Magnetic resonance imaging method, device and equipment of pulse gating system and storage medium Download PDF

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CN114720930A
CN114720930A CN202210369067.7A CN202210369067A CN114720930A CN 114720930 A CN114720930 A CN 114720930A CN 202210369067 A CN202210369067 A CN 202210369067A CN 114720930 A CN114720930 A CN 114720930A
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pulse
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microcontroller
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张敦友
林先钗
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Beijing Wandong Medical Technology Co ltd
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Beijing Wandong Medical Technology Co ltd
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    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/54Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
    • G01R33/56Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/567Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution gated by physiological signals, i.e. synchronization of acquired MR data with periodical motion of an object of interest, e.g. monitoring or triggering system for cardiac or respiratory gating
    • G01R33/5673Gating or triggering based on a physiological signal other than an MR signal, e.g. ECG gating or motion monitoring using optical systems for monitoring the motion of a fiducial marker

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Abstract

The application provides a magnetic resonance imaging method, a device, equipment and a storage medium of a pulse gating system, which are applied to the technical field of magnetic resonance, and the method comprises the following steps: the finger-clipped pulse sensor acquires an artery pulse signal on the surface of the skin of each finger tip at any time; the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signals to obtain pulse digital signals; the pulse analog-to-digital converter sends a pulse digital signal to the microcontroller through the SPI three-wire interface; the microcontroller carries out fast Fourier transform processing on the pulse digital signals according to the original data matrix to obtain pulse waveform data; microcontroller passes through the cable interface and uploads pulse waveform data to pulse gate host computer, the beneficial effect of this application: the magnetic resonance imaging system adopts a pressure-sensitive sensing technology, can stably and accurately acquire pulse wave signals of human finger tips, has low power consumption, high reliability, strong anti-interference capability and better adaptability, and is favorable for improving the quality of magnetic resonance pulse imaging.

Description

Magnetic resonance imaging method, device and equipment of pulse gating system and storage medium
Technical Field
The present application relates to the field of magnetic resonance technology, and in particular, to a magnetic resonance imaging method, apparatus, device and storage medium for a pulse gating system.
Background
The PPG (Photoplethysmography, PPG for short) is used for obtaining the information of the artery pulsation; the PPG technology is a non-invasive detection method for detecting blood volume change in living body tissues by means of a photoelectric means, when light beams with a certain wavelength irradiate the surface of the skin at the finger tip, the contraction and expansion of blood vessels can affect the transmission or reflection of light every heartbeat, most of the existing magnetic resonance imaging systems are based on the PPG technology, generally collect fingertip pulse wave information of a human body on the basis of an LED light source and a detector in a finger sleeve form, perform analog-to-digital conversion on pulse signals through a front-end analog circuit, perform signal interaction with an upper computer through a micro control unit, and finally output a gate control trigger signal; however, since light emitted by the fluorescent lamp, the decorative lamp strip and the display screen in the shielding room of the magnetic resonance imaging system can cause frequency components causing measurement errors, in addition to light interference, a gradient line graph inevitably vibrates with a certain intensity when the magnetic resonance imaging system scans, so that the technical problem of eliminating blood vessel pulsation artifacts in clinical application of the magnetic resonance imaging system is still difficult to solve, and the quality of magnetic resonance pulse imaging is directly influenced.
Disclosure of Invention
In view of this, the embodiment of the present application provides a magnetic resonance imaging method for a pulse gating system, which can stably and accurately acquire an arterial pulse signal on the skin surface of each finger tip at any time by using a pressure-sensitive sensing technology, and is low in power consumption, high in reliability, strong in anti-interference capability, and beneficial to improving the quality of magnetic resonance pulse imaging.
In a first aspect, an embodiment of the present application provides a magnetic resonance imaging method of a pulse gating system, including:
the finger-clipped pulse sensor acquires an artery pulse signal on the surface of the skin of each finger tip at any time;
the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signals to obtain pulse digital signals;
the pulse analog-to-digital converter sends the pulse digital signal to a microcontroller through an SPI three-wire interface;
the microcontroller carries out fast Fourier transform processing on the pulse digital signals according to an original data matrix to obtain pulse waveform data, wherein the original data matrix is a two-dimensional array with pulse digital signal positioning information;
and the microcontroller uploads the pulse waveform data to a pulse gate control upper computer through a cable interface.
With reference to the first aspect, the present embodiments provide a first possible implementation manner of the first aspect, in which the finger-clip type pulse sensor acquires an arterial pulse signal from a skin surface of each finger tip at any time, and includes:
the finger-clipped pulse sensor acquires a differential arterial pulse signal on one path of the skin surface of each finger tip at any moment;
the finger-clipped pulse sensor converts the pressure change generated by the acquired arterial pulse signal into a pulse wave signal which changes along with time.
With reference to the first possible implementation manner of the first aspect, this application provides a second possible implementation manner of the first aspect, where the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signal to obtain a pulse digital signal, and the method includes:
the front-end sampling card acquires the pulse wave signals from the finger-clipped pulse sensor, and sequentially performs filtering processing, signal amplification processing and signal isolation processing on the pulse wave signals to obtain pulse analog signals, wherein the pulse analog-to-digital converter comprises the front-end sampling card, an analog-to-digital conversion chip and an A/D converter;
and the front-end sampling card inputs the pulse analog signals to a differential input end of the A/D converter for analog-to-digital conversion to obtain pulse digital signals.
With reference to the first possible implementation manner or the second possible implementation manner of the first aspect, an embodiment of the present application provides a third possible implementation manner of the first aspect, where the pulse analog-to-digital converter sends the pulse digital signal to the microcontroller through an SPI three-wire interface, and the method includes:
the output end of the pulse analog-to-digital converter is connected with the microcontroller through an SPI three-wire interface;
the pulse analog-to-digital converter is configured with a register in the analog-to-digital conversion chip through an SPI three-wire interface, and sends the pulse digital signal stored in the register to a microcontroller through a clock signal and a control signal of the SPI three-wire interface.
With reference to the first possible implementation manner or the second possible implementation manner of the first aspect, an embodiment of the present application provides a fourth possible implementation manner of the first aspect, where the microcontroller performs fast fourier transform processing on the pulse digital signal according to an original data matrix to obtain pulse waveform data, and the method includes:
the microcontroller inputs the real part matrix and the imaginary part matrix of the pulse digital signal with the positioning information into a Fourier transformer;
the Fourier transformer is used for taking a module of a corresponding point of the two matrixes to obtain a new matrix;
and the Fourier transformer respectively carries out fast Fourier transform processing in two directions according to the rows and the columns of the new matrix to obtain pulse waveform data.
With reference to the first possible implementation manner or the second possible implementation manner of the first aspect, an embodiment of the present application provides a fifth possible implementation manner of the first aspect, where the microcontroller uploads the pulse waveform data to the pulse gating upper computer through a cable interface, and the pulse gating upper computer includes:
the microcontroller is in communication connection with the pulse gate control upper computer through an RS232 cable interface;
after communication is established, the pulse gating upper computer sends a control instruction and a configuration information instruction to the microcontroller;
the microcontroller uploads the pulse waveform data to the pulse gate control upper computer through an RS232 cable interface according to the pulse gate control upper computer control instruction;
and the pulse gating upper computer performs visual display on the received pulse waveform data through a graphical user interface.
With reference to the first possible implementation manner or the second possible implementation manner of the first aspect, an embodiment of the present application provides a sixth possible implementation manner of the first aspect, where the pulse gating upper computer performs visual display on pulse waveform data through a graphical user interface, and specifically includes:
the pulse gating upper computer is used for visually displaying the pulse waveform data through a graphic user interface, and the visual display comprises: ascending branches and descending branches; wherein, the ascending branch shows that when the heart contracts, the blood vessel wall is expanded, the fingertip pulse pressure is increased, and the ascending branch of the pulse waveform, namely the wave peak value is formed; the descending branch means that when the heart is in diastole, the blood vessel wall is gradually retracted, the fingertip pulse pressure is reduced, and the descending branch of the pulse waveform is formed.
In a second aspect, an embodiment of the present application further provides an apparatus for magnetic resonance imaging of a pulse gating system, where the apparatus includes:
the acquisition module is used for acquiring an arterial pulse signal on the surface of the skin of each finger tip at any moment by the finger-clip type pulse sensor;
the conversion module is used for carrying out analog-to-digital conversion on the acquired pulse wave signals by the pulse analog-to-digital converter to obtain pulse digital signals;
the sending module is used for sending the pulse digital signal to the microcontroller through the SPI three-wire interface by the pulse analog-to-digital converter;
the processing module is used for the microcontroller to perform fast Fourier transform processing on the pulse digital signals according to an original data matrix to obtain pulse waveform data, wherein the original data matrix is a two-dimensional array with pulse digital signal positioning information;
and the uploading module is used for uploading the pulse waveform data to a pulse gating upper computer through a cable interface by the microcontroller.
In a third aspect, an embodiment of the present application further provides a computer device, which includes a memory, a processor, and a computer program stored in the memory and executable on the processor, and the processor implements the magnetic resonance imaging method steps of the pulse gating system of the above claims when executing the computer program.
In a fourth aspect, the present application provides a computer-readable storage medium having a computer program stored thereon, which, when being executed by a processor, performs the steps of a magnetic resonance imaging method, such as a pulse gating system.
Compared with the prior art that the pulse wave signals of the fingertips of a human body are acquired by adopting a PPG technology, the magnetic resonance imaging method of the pulse gating system provided by the embodiment of the application can stably and accurately acquire the pulse wave signals of the finger tips by adopting a finger-clamping type pressure-sensitive sensing technology, and has better pressure-sensitive technology adaptability and stronger interference resistance in the magnetic resonance imaging system. The method includes that a finger-clipped pulse sensor collects arterial pulse signals on the surface of skin at each finger tip at any time; the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signals to obtain pulse digital signals; the pulse analog-to-digital converter sends a pulse digital signal to the microcontroller through the SPI three-wire interface; the microcontroller carries out fast Fourier transform processing on the pulse digital signals according to the original data matrix to obtain pulse waveform data; and the microcontroller uploads the pulse waveform data to a pulse gate control upper computer through an RS-232 cable interface. Particularly, the finger-clipped pulse sensor is adopted in the magnetic resonance imaging system, so that the arterial pulse signal on the surface of the skin of each finger tip at any moment can be accurately acquired, and the finger-clipped pulse sensor has the characteristics of small volume, low power consumption, high reliability, strong anti-interference capability, more stable acquisition of the pulse wave signal of the finger tip of a human body and better adaptability; interference caused by fingertip signal measurement error and vibration acquired based on PPG technology is effectively avoided, the pulse analog-to-digital converter sends pulse digital signals to the microcontroller through the SPI three-wire interface, the steps of magnetic resonance scanning iterative computation and signal modulation are avoided, the technical problems of long time consumption and difficult parameter selection are effectively solved, and the quality of magnetic resonance pulse imaging is improved.
In order to make the aforementioned objects, features and advantages of the present application more comprehensible, preferred embodiments accompanied with figures are described in detail below.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present application and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained from the drawings without inventive effort.
Fig. 1 shows a flowchart of a magnetic resonance imaging method of a pulse gating system according to an embodiment of the present application.
Fig. 2 shows a functional block diagram of a magnetic resonance imaging method of a pulse gating system according to an embodiment of the present application.
Fig. 3 is a schematic flow chart illustrating the acquisition of an arterial pulse signal in a magnetic resonance imaging method of a pulse gating system according to an embodiment of the present application.
Fig. 4 is a schematic flowchart illustrating an analog-to-digital conversion of a pulse wave signal in a magnetic resonance imaging method of a pulse gating system according to an embodiment of the present application.
Fig. 5 is a schematic flow chart illustrating a process of sending pulse digital signals in a magnetic resonance imaging method of a pulse gating system according to an embodiment of the present application.
Fig. 6 is a schematic flow chart illustrating a process of obtaining pulse waveform data in a magnetic resonance imaging method of a pulse gating system according to an embodiment of the present application.
Fig. 7 is a schematic flowchart illustrating a procedure of uploading pulse waveform data to a pulse gating host in an mri method of a pulse gating system according to an embodiment of the present disclosure.
Fig. 8 shows a schematic structural diagram of a magnetic resonance imaging apparatus of a pulse gating system according to an embodiment of the present application.
Fig. 9 shows a schematic structural diagram of a computer device provided in an embodiment of the present application.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application clearer, the technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all the embodiments. The components of the embodiments of the present application, generally described and illustrated in the figures herein, can be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the present application, presented in the accompanying drawings, is not intended to limit the scope of the claimed application, but is merely representative of selected embodiments of the application. All other embodiments, which can be derived by a person skilled in the art from the embodiments of the present application without making any creative effort, shall fall within the protection scope of the present application.
The heartbeat of a human body can generate a pressure wave to be transmitted through a blood vessel, the pressure wave can slightly change the diameter of the blood vessel, the information of the pulsation of the arterial blood vessel is obtained by utilizing a Photoplethysmography (PPG for short), the PPG technology is often applied to wearable equipment such as a watch or a wrist guard and the like to realize continuous detection of heart rate information, in magnetic resonance imaging, the physiological motion artifact of the human body is generally inhibited by the magnetic resonance physiological gating technology, when the magnetic resonance blood vessel imaging is carried out, the elimination of the blood vessel pulsation artifact is a priority consideration, a pulse gating system for the magnetic resonance imaging acquires the pulse information of the human body in real time to be processed and applied, and finally sends out a gating trigger signal to a spectrometer of the magnetic resonance system, so that the magnetic resonance system is guided to carry out scanning.
Considering that when the artery blood vessel information of the human body is acquired according to the PPG technology, light can cause measurement errors and reduce the sensitivity of signals; based on this, the embodiments of the present application provide a magnetic resonance imaging method of a pulse gating system, which is described below by way of example.
Some embodiments of the present application will be described in detail below with reference to the accompanying drawings. The embodiments described below and the features of the embodiments can be combined with each other without conflict.
Fig. 1 is a flow chart of a magnetic resonance imaging method of a pulse gating system according to an embodiment of the present application; as shown in fig. 1 and 2, the method specifically comprises the following steps:
and step S10, the finger-clipped pulse sensor collects the artery pulse signals of the skin surface of each finger tip at any time.
Step S10 is implemented by disposing the finger clip at the finger tip of a human finger, collecting the artery pulse signal on the skin surface of each finger tip at any time by the finger clip type pulse sensor, and converting the collected artery pulse signal into a pulse wave signal varying with time.
Step S20, the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signal to obtain a pulse digital signal.
In the specific implementation of step S20, the finger-clipped pulse sensor inputs the acquired pulse wave signal into the pulse analog-to-digital converter, and according to the nyquist sampling theorem, the pulse analog-to-digital converter performs sampling processing on any instantaneous pulse wave signal that continuously changes with time, and according to a preset sampling period, performs a/D analog-to-digital conversion on an amplitude value corresponding to the pulse wave signal in each sampling time period to obtain a pulse digital signal.
And step S30, the pulse analog-to-digital converter sends the pulse digital signal to the microcontroller through the SPI three-wire interface.
Step S30 is implemented in a concrete way, the pulse analog-digital converter establishes communication with the microcontroller in a serial way through the embedded SPI three-wire interface, reads and writes pulse digital signals in the pulse analog-digital conversion chip through the SPI three-wire interface, and transmits the pulse digital signals to the microcontroller in a data stream mode, wherein the pulse analog-digital converter adopts a 16-bit high-precision pulse analog-digital converter; the pulse analog-to-digital conversion chip is an AD775 analog-to-digital conversion chip.
And step S40, the microcontroller performs fast Fourier transform processing on the pulse digital signals according to the original data matrix to obtain pulse waveform data, wherein the original data matrix is a two-dimensional array with pulse digital signal positioning information.
When the step S40 is implemented specifically, the microcontroller inputs the two-dimensional array with pulse digital signal positioning information into the fourier transformer, the fourier transformer performs fast fourier transform processing in two directions respectively according to the rows and columns of the two-dimensional array to obtain pulse waveform data, and the microcontroller selects the STM32F103CBT6 processor of ST jew semiconductor corporation.
And step S50, the microcontroller uploads the pulse waveform data to a pulse gate control upper computer through a cable interface.
When the step S50 is implemented specifically, the microcontroller is in communication connection with the pulse gate control upper computer through the cable interface, the pulse gate control upper computer sends a control instruction and a hardware configuration instruction to the microcontroller according to preset parameters of the controller unit, the microcontroller uploads pulse waveform data to the pulse gate control upper computer through the RS-232 cable interface according to the control instruction, the pulse gate control upper computer receives the pulse waveform data and then performs visual display through the graphical user interface, and meanwhile, the microcontroller sends the pulse waveform data to the client through the RS-232 cable interface.
In a possible implementation, fig. 3 shows a schematic flow chart of acquiring an arterial pulse signal in a magnetic resonance imaging method of a pulse gating system provided in an embodiment of the present application; in step S10, the finger-clipped pulse sensor acquires an artery pulse signal from the skin surface of each finger tip at any time, and includes:
step S101, the finger-clipped pulse sensor collects one path of differential arterial pulse signals on the surface of the skin of each finger tip at any time.
Step S102, the finger-clip type pulse sensor converts the pressure change generated by the acquired artery pulse signal into a pulse wave signal changing along with time.
When the steps S101 and S102 are implemented specifically, the output end of the finger-clipped pulse sensor is connected to the input ends of two signal lines which are equal in length, equal in width, and closely adjacent to each other and are on the same layer, the output ends of the two signal lines are connected to the input end of the pulse analog-to-digital converter, the finger-clipped pulse sensor collects one path of differential arterial pulse signal on the skin surface of each finger end at any time through an electric conductor, extracts the pressure change generated by the arterial pulse signal through an operational amplifier, and converts the pressure into a pulse wave signal changing along with time.
In a possible implementation, fig. 4 shows a schematic flow chart of performing analog-to-digital conversion on a pulse wave signal in a magnetic resonance imaging method of a pulse gating system provided in an embodiment of the present application; in the step S20, the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signal to obtain a pulse digital signal, including:
step S201, the front end sampling card obtains a pulse wave signal from the finger-clipped pulse sensor, and sequentially performs filtering, signal amplification and signal isolation on the pulse wave signal to obtain a pulse analog signal, wherein the pulse analog-to-digital converter includes the front end sampling card, an a/D converter and a controller unit.
Step S202, the front-end sampling card inputs the pulse analog signal to a differential input end of the A/D converter for analog-to-digital conversion, and a pulse digital signal is obtained.
In the specific implementation of steps S201 and S202, the finger-clipped pulse sensor inputs the acquired pulse wave signals to the pulse analog-to-digital converter through two signal lines on the same layer, a front-end sampling card, an analog-to-digital conversion chip and an a/D converter are integrated in the pulse analog-to-digital converter, the front-end sampling card samples any instantaneous pulse wave signal continuously changing with time through a single high-speed channel, filters the pulse wave signal without change, sequentially amplifies the signal amplitude, removes noise and amplifies the power of the processed pulse wave signal, isolates the amplified pulse wave signal, obtains an analog pulse signal after multiple amplification and filtering, sends the obtained analog pulse signal to the differential input of the a/D converter by the front-end sampling card, sets the optimal conversion frequency according to different frequency ranges, the A/D converter samples the pulse analog signal according to the gradient magnetic field and the size of the layer, and the A/D converter performs analog-to-digital conversion on the speed and the precision of the pulse analog signal to obtain a pulse digital signal.
In a possible implementation, fig. 5 shows a schematic flow chart of sending pulse digital signals in a magnetic resonance imaging method of a pulse gating system provided in an embodiment of the present application; in step S30, the pulse analog-to-digital converter sends the pulse digital signal to the microcontroller through the SPI three-wire interface, including:
and step S301, the output end of the pulse analog-to-digital converter is connected with the microcontroller through the SPI three-wire interface.
Step S302, the pulse analog-to-digital converter configures a register in the analog-to-digital conversion chip through the SPI three-wire interface, and sends a pulse digital signal stored in the register to the microcontroller through a clock signal and a control signal of the SPI three-wire interface.
When the steps S301 and S302 are implemented specifically, the output end of the pulse analog-to-digital converter establishes communication with the microcontroller through the embedded SPI three-wire interface, the pulse analog-to-digital converter configures the register in the analog-to-digital conversion chip through the SPI three-wire interface according to the clock signal of the timer and the control signal of the built-in controller, when the pulse analog-to-digital chip sends a clock signal to the clock input end of the microcontroller, the microcontroller is conducted with the clock input end of the pulse analog-to-digital chip, when the clock signal is changed from a low level to a high level, a rising edge is completed, the pulse analog-to-digital chip sends the pulse digital signal stored in the register to the microcontroller, the microcontroller selects the STM32F103CBT6 processor, and the timer and the two controllers are arranged inside the microcontroller.
In a possible implementation, fig. 6 is a schematic flow chart illustrating obtaining pulse waveform data in a magnetic resonance imaging method of a pulse gating system according to an embodiment of the present application; in the step S40, the microcontroller performs fast fourier transform processing on the pulse digital signal according to the original data matrix to obtain pulse waveform data, including:
step S401, the microcontroller inputs the real part matrix and the imaginary part matrix of the pulse digital signal with the positioning information into a Fourier transformer.
Step S402, taking a module of the corresponding point of the two matrixes by the Fourier transformer to obtain a new matrix.
And step S403, the Fourier transformer respectively carries out fast Fourier transform processing in two directions according to the rows and columns of the new matrix to obtain pulse waveform data.
When the steps S401, S402, and S403 are implemented specifically, the microcontroller reads three-dimensional coordinate data of the pulse digital signal, generates two original data matrices corresponding to the pulse digital signal, one representing a real part matrix of the signal, and the other representing an imaginary part matrix, inputs the two original matrices into the fourier transformer, and the fourier transformer performs a modulus operation on corresponding points of the two matrices to obtain a new matrix, and performs fast fourier transform in two directions according to rows and columns of the new matrix, respectively, to obtain pulse waveform data.
In a possible implementation, fig. 7 is a schematic flow chart illustrating uploading of pulse waveform data to a pulse gating upper computer in a magnetic resonance imaging method of a pulse gating system according to an embodiment of the present application; in above-mentioned step S50, microcontroller passes through the cable interface and uploads pulse waveform data to pulse gate host computer, includes:
step S501, the microcontroller is in communication connection with a pulse gate control upper computer through an RS232 cable interface;
step S502, after communication is established, the pulse gate control upper computer sends a control instruction and a configuration information instruction to the microcontroller;
step S503, the microcontroller uploads the pulse waveform data to the pulse gate upper computer through an RS232 cable interface according to the control instruction of the pulse gate upper computer;
and step S504, the pulse gating upper computer performs visual display on the received pulse waveform data through a graphical user interface.
When the steps S501, S502, S503 and S504 are implemented specifically, after the microcontroller establishes communication with the pulse gating upper computer through the RS232 cable interface, the pulse gating upper computer responds to an operation request of a technician, and sends a control instruction and a configuration information instruction to the microcontroller in the form of binary codes according to the control pins, where the configuration information instruction includes: the system comprises a console configuration instruction, a main control image display configuration instruction, a secondary control information display configuration instruction, a network adapter configuration instruction and a frequency spectrograph interface configuration instruction, wherein the pulse gating upper computer also has the functions of data management, image archiving, printing, machine self-checking and the like; then, the microcontroller uploads pulse waveform data to a pulse gating upper computer through an RS232 cable interface according to a configured control instruction, and the pulse gating upper computer visually displays an ascending branch and an arterial waveform descending branch of a pulse blood pressure waveform through a graphic user interface, wherein the ascending branch indicates that when the heart contracts, a blood vessel wall is expanded, the fingertip pulse pressure is increased, and the ascending branch of the pulse waveform, namely a wave peak value, is formed; the descending branch means that when the heart is in diastole, the blood vessel wall is gradually retracted, the fingertip pulse pressure is reduced, and the descending branch of the pulse waveform is formed.
Fig. 8 is a schematic structural diagram of a magnetic resonance imaging apparatus of a pulse gating system according to an embodiment of the present application, and as shown in fig. 8, the apparatus includes:
the acquisition module 601 is used for acquiring an arterial pulse signal on the surface of the skin of each finger tip at any moment by using the finger-clip type pulse sensor;
the conversion module 602 is configured to perform analog-to-digital conversion on the acquired pulse wave signal by using a pulse analog-to-digital converter to obtain a pulse digital signal;
the sending module 603 is configured to send the pulse digital signal to the microcontroller through the SPI three-wire interface by the pulse analog-to-digital converter;
the processing module 604 is configured to perform fast fourier transform processing on the pulse digital signal by the microcontroller according to an original data matrix to obtain pulse waveform data, where the original data matrix is a two-dimensional array with pulse digital signal positioning information;
and an uploading module 605 for uploading the pulse waveform data to the pulse gating upper computer by the microcontroller through the cable interface.
When the finger clip is specifically implemented, the finger clip is arranged at the finger tip position of a human finger, the finger clip collects arterial pulse signals on the skin surface of each finger tip at any moment through a built-in finger clip type pulse sensor, and the collected arterial pulse signals are converted into pulse wave signals changing along with time; the finger-clipped pulse sensor inputs the acquired pulse wave signals into a pulse analog-to-digital converter, the pulse analog-to-digital converter samples any instant pulse wave signals continuously changing along with time according to the Nyquist sampling theorem, and A/D analog-to-digital conversion is carried out on amplitude values corresponding to the pulse wave signals in each sampling time period according to a preset sampling period to obtain pulse digital signals; the pulse analog-to-digital converter establishes communication with the microcontroller in a serial mode through an embedded SPI three-wire interface, reads pulse digital signals written into a pulse analog-to-digital conversion chip through the SPI three-wire interface and transmits the pulse digital signals to the microcontroller in a data flow mode; the microcontroller inputs the two-dimensional array with the pulse digital signal positioning information into a Fourier transformer, and the Fourier transformer respectively carries out fast Fourier transform processing in two directions according to the rows and the columns of the two-dimensional array to obtain pulse waveform data; the pulse gating upper computer sends a control instruction and a hardware configuration instruction to the microcontroller according to preset parameters of the controller unit, the microcontroller uploads pulse waveform data to the pulse gating upper computer through the RS-232 cable interface according to the control instruction, and the pulse gating upper computer performs visual display through the graphical user interface after receiving the pulse waveform data.
Corresponding to the magnetic resonance imaging method of the pulse gating system in fig. 1, an embodiment of the present application further provides a computer apparatus 70, fig. 9, as shown in fig. 9, the apparatus includes a memory 701, a processor 702, and a computer program stored on the memory 701 and executable on the processor 702, wherein the processor 702 implements the method when executing the computer program.
The finger-clipped pulse sensor acquires an artery pulse signal on the surface of the skin of each finger tip at any time;
the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signals to obtain pulse digital signals;
the pulse analog-to-digital converter sends a pulse digital signal to the microcontroller through the SPI three-wire interface;
the microcontroller carries out fast Fourier transform processing on the pulse digital signals according to an original data matrix to obtain pulse waveform data, wherein the original data matrix is a two-dimensional array with pulse digital signal positioning information;
and the microcontroller uploads the pulse waveform data to the pulse gate control upper computer through a cable interface.
Corresponding to the magnetic resonance imaging method of the pulse gating system in fig. 1, an embodiment of the present application further provides a computer readable storage medium having a computer program stored thereon, where the computer program is executed by a processor to perform the following steps:
the finger-clipped pulse sensor acquires arterial pulse signals on the surface of the skin of each finger tip at any time;
the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signals to obtain pulse digital signals;
the pulse analog-to-digital converter sends a pulse digital signal to the microcontroller through the SPI three-wire interface;
the microcontroller carries out fast Fourier transform processing on the pulse digital signals according to an original data matrix to obtain pulse waveform data, wherein the original data matrix is a two-dimensional array with pulse digital signal positioning information;
and the microcontroller uploads the pulse waveform data to the pulse gate control upper computer through a cable interface.
Based on the analysis, compared with the related technology that the pulse wave signals of the fingertips of the human body are acquired by adopting a PPG technology, the finger-clipped pressure-sensitive sensing technology provided by the embodiment of the application can stably and accurately acquire the pulse wave signals of the fingertips, and the finger-clipped pulse sensor has the advantages of small volume, low power consumption, high reliability, strong anti-interference capability, more stable acquisition of the pulse wave signals of the fingertips of the human body and better adaptability; interference caused by measurement error and vibration of fingertip signal collected based on PPG technology is effectively avoided.
The magnetic resonance imaging apparatus of the pulse gating system provided by the embodiment of the application can be specific hardware on the device or software or firmware installed on the device. The device provided by the embodiment of the present application has the same implementation principle and technical effect as the foregoing method embodiments, and for the sake of brief description, reference may be made to the corresponding contents in the foregoing method embodiments where no part of the device embodiments is mentioned. It is clear to those skilled in the art that, for convenience and brevity of description, the specific working processes of the apparatus and the unit described above may refer to the corresponding processes in the foregoing method embodiments, and are not described herein again.
In the embodiments provided in the present application, it should be understood that the disclosed apparatus and method may be implemented in other ways. The above-described embodiments of the apparatus are merely illustrative, and for example, a division of a unit is merely a division of one logic function, and there may be other divisions when actually implemented, and for example, a plurality of units or components may be combined or integrated into another system, or some features may be omitted, or not executed. In addition, the shown or discussed mutual coupling or direct coupling or communication connection may be an indirect coupling or communication connection of devices or units through some communication interfaces, and may be in an electrical, mechanical or other form.
Units described as separate parts may or may not be physically separate, and parts displayed as units may or may not be physical units, may be located in one place, or may be distributed on a plurality of network units. Some or all of the units can be selected according to actual needs to achieve the purpose of the solution of the embodiment.
In addition, functional units in the embodiments provided in the present application may be integrated into one processing unit, or each unit may exist alone physically, or two or more units are integrated into one unit.
The functions, if implemented in the form of software functional units and sold or used as a stand-alone product, may be stored in a computer readable storage medium. Based on such understanding, the technical solution of the present application or portions thereof that substantially contribute to the prior art may be embodied in the form of a software product stored in a storage medium and including instructions for causing a computer device (which may be a personal computer, a server, or a network device) to execute all or part of the steps of the method according to the embodiments of the present application. And the aforementioned storage medium includes: a U-disk, a removable hard disk, a Read-Only Memory (ROM), a Random Access Memory (RAM), a magnetic disk or an optical disk, and other various media capable of storing program codes.
It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus once an item is defined in one figure, it need not be further defined and explained in subsequent figures, and moreover, the terms "first", "second", "third", etc. are used merely to distinguish one description from another and are not to be construed as indicating or implying relative importance.
Finally, it should be noted that: the above-mentioned embodiments are only specific embodiments of the present application, and are used for illustrating the technical solutions of the present application, but not limiting the same, and the scope of the present application is not limited thereto, and although the present application is described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: any person skilled in the art can modify or easily conceive the technical solutions described in the foregoing embodiments or equivalent substitutes for some technical features within the technical scope disclosed in the present application; such modifications, changes or substitutions do not depart from the spirit and scope of the present disclosure, which should be construed in light of the above teachings. Are intended to be covered by the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.

Claims (10)

1. A method of magnetic resonance imaging for a pulse gating system, comprising:
the finger-clipped pulse sensor acquires an artery pulse signal on the surface of the skin of each finger tip at any time;
the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signals to obtain pulse digital signals;
the pulse analog-to-digital converter sends the pulse digital signal to a microcontroller through an SPI three-wire interface;
the microcontroller carries out fast Fourier transform processing on the pulse digital signals according to an original data matrix to obtain pulse waveform data, wherein the original data matrix is a two-dimensional array with pulse digital signal positioning information;
and the microcontroller uploads the pulse waveform data to a pulse gate control upper computer through a cable interface.
2. The method of magnetic resonance imaging of a pulse gating system according to claim 1, wherein the finger-clipped pulse sensor acquires the arterial pulse signal of the skin surface of each finger tip at any time, comprising:
the finger-clipped pulse sensor acquires a differential arterial pulse signal on one path of the skin surface of each finger tip at any moment;
the finger-clipped pulse sensor converts the pressure change generated by the acquired arterial pulse signal into a pulse wave signal which changes along with time.
3. The magnetic resonance imaging method of the pulse gating system of claim 1, wherein the pulse analog-to-digital converter performs analog-to-digital conversion on the acquired pulse wave signal to obtain a pulse digital signal, comprising:
the front-end sampling card acquires the pulse wave signals from the finger-clipped pulse sensor, and sequentially performs filtering processing, signal amplification processing and signal isolation processing on the pulse wave signals to obtain pulse analog signals, wherein the pulse analog-to-digital converter comprises the front-end sampling card, an analog-to-digital conversion chip and an A/D converter;
and the front-end sampling card inputs the pulse analog signals to a differential input end of the A/D converter for analog-to-digital conversion to obtain pulse digital signals.
4. The magnetic resonance imaging method of the pulse gating system according to claim 1, wherein the pulse analog-to-digital converter sends the pulse digital signal to the microcontroller through the SPI three-wire interface, comprising:
the output end of the pulse analog-to-digital converter is connected with the microcontroller through an SPI three-wire interface;
the pulse analog-digital converter is configured with a register in the analog-digital conversion chip through the SPI three-wire interface, and sends the pulse digital signal stored in the register to the microcontroller through a clock signal and a control signal of the SPI three-wire interface.
5. The method of claim 1, wherein the microcontroller performs fast fourier transform processing on the pulse digital signal according to a raw data matrix to obtain pulse waveform data, and the method comprises:
the microcontroller inputs the real part matrix and the imaginary part matrix of the pulse digital signal with the positioning information into a Fourier transformer;
the Fourier transformer is used for taking a module of a corresponding point of the two matrixes to obtain a new matrix;
and the Fourier transformer respectively carries out fast Fourier transform processing in two directions according to the rows and the columns of the new matrix to obtain pulse waveform data.
6. The method of magnetic resonance imaging of a pulse gating system according to claim 1, wherein the microcontroller uploads the pulse waveform data to a pulse gating host computer through a cable interface, comprising:
the microcontroller is in communication connection with the pulse gate control upper computer through an RS232 cable interface;
after communication is established, the pulse gating upper computer sends a control instruction and a configuration information instruction to the microcontroller;
the microcontroller uploads the pulse waveform data to the pulse gate control upper computer through an RS232 cable interface according to the pulse gate control upper computer control instruction;
and the pulse gating upper computer performs visual display on the received pulse waveform data through a graphical user interface.
7. The magnetic resonance imaging method of the pulse gating system according to claim 1, wherein the pulse gating upper computer performs visual display of the pulse waveform data through a graphical user interface, and specifically comprises:
the pulse gating upper computer carries out visual display on the pulse waveform data through a graphic user interface, the visual display comprises: ascending branches and descending branches; wherein, the ascending branch shows that when the heart contracts, the blood vessel wall is expanded, the fingertip pulse pressure is increased, and the ascending branch of the pulse waveform, namely the wave peak value is formed; the descending branch means that when the heart is in diastole, the blood vessel wall is gradually retracted, the fingertip pulse pressure is reduced, and the descending branch of the pulse waveform is formed.
8. An apparatus for magnetic resonance imaging of a pulse gating system, the apparatus comprising:
the acquisition module is used for acquiring an arterial pulse signal on the surface of the skin of each finger tip at any moment by the finger-clip type pulse sensor;
the conversion module is used for carrying out analog-to-digital conversion on the acquired pulse wave signals by the pulse analog-to-digital converter to obtain pulse digital signals;
the sending module is used for sending the pulse digital signal to the microcontroller through the SPI three-wire interface by the pulse analog-to-digital converter;
the processing module is used for the microcontroller to perform fast Fourier transform processing on the pulse digital signals according to an original data matrix to obtain pulse waveform data, wherein the original data matrix is a two-dimensional array with pulse digital signal positioning information;
and the uploading module is used for uploading the pulse waveform data to a pulse gating upper computer through a cable interface by the microcontroller.
9. A computer device comprising a memory, a processor and a computer program stored on the memory and executable on the processor, characterized in that the steps of the method of any of the preceding claims 1 to 7 are implemented when the computer program is executed by the processor.
10. A computer-readable storage medium, having stored thereon a computer program which, when being executed by a processor, is adapted to carry out the steps of the method according to any one of claims 1 to 7.
CN202210369067.7A 2022-04-08 2022-04-08 Magnetic resonance imaging method, device and equipment of pulse gating system and storage medium Pending CN114720930A (en)

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