CN110840405A - Manufacturing method of flexible array sensor and pulse condition detection system based on flexible array sensor - Google Patents

Manufacturing method of flexible array sensor and pulse condition detection system based on flexible array sensor Download PDF

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CN110840405A
CN110840405A CN201911172242.8A CN201911172242A CN110840405A CN 110840405 A CN110840405 A CN 110840405A CN 201911172242 A CN201911172242 A CN 201911172242A CN 110840405 A CN110840405 A CN 110840405A
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pulse
flexible
array sensor
flexible array
pulse condition
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王凤霞
章云霖
陈涛
孙立宁
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Suzhou University
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Suzhou University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4854Diagnosis based on concepts of traditional oriental medicine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802Sensor mounted on worn items
    • A61B5/681Wristwatch-type devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813Specially adapted to be attached to a specific body part
    • A61B5/6824Arm or wrist
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6843Monitoring or controlling sensor contact pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04Arrangements of multiple sensors of the same type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/12Manufacturing methods specially adapted for producing sensors for in-vivo measurements
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/164Details of sensor housings or probes; Details of structural supports for sensors the sensor is mounted in or on a conformable substrate or carrier
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16Details of sensor housings or probes; Details of structural supports for sensors
    • A61B2562/168Fluid filled sensor housings

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
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  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

The embodiment of the invention discloses a manufacturing method of a flexible array sensor and a pulse condition detection system based on the flexible array sensor. The pulse condition detection system based on the flexible array sensor comprises an external force applying module for applying pressure to a radial artery, the flexible array sensor which is located at a preset position of the radial artery and used for sensing the pulse pressure at the preset position, a signal processing module which is connected with the output end of the flexible array sensor and used for processing the output signal of the flexible array sensor, a pulse condition acquisition module which is connected with the signal processing module and used for realizing signal conversion and storage, and a pulse condition distinguishing module which is connected with the pulse condition acquisition module and used for carrying out feature extraction and analysis according to the signal in the pulse condition acquisition module, realizing three-dimensional pulse condition presentation and distinguishing different pulse conditions. The pulse condition detection system is convenient to use and simple to wear, and can visually present pulse condition distribution.

Description

Manufacturing method of flexible array sensor and pulse condition detection system based on flexible array sensor
Technical Field
The invention relates to the technical field of medical instruments, in particular to a pulse condition detection system based on a flexible array sensor and a manufacturing method of the flexible array sensor used for the pulse condition detection system.
Background
TCM is a treasure of Chinese nationality and is a medical discipline for studying human physiology, pathology, and disease diagnosis and prevention. The pulse condition is an important basis for the diagnosis of traditional Chinese medicine, which refers to the condition of rapid, slow, strong, weak and deep pulse, and is the image and dynamic display of pulse. In the process of traditional Chinese medicine diagnosis, doctors determine pulse conditions by feeling pulses. The pulse feeling process is as follows: the doctor of traditional Chinese medicine applies different pressures to the cun, guan and chi parts of the patient's radial artery by three fingers to feel the process of different pulsation of the patient's artery. Because the traditional Chinese medicine diagnosis of pulse conditions depends on the subjective feeling of doctors on pulse fluctuation, the feeling of fingers cannot be expressed accurately and quantitatively, and thus the traditional Chinese medicine diagnosis cannot be accepted by broad scholars. Further, since the pulse condition is limited by the level of the doctor and the accuracy of the physical perception, the accuracy of pulse condition diagnosis and the practical application in modern medicine are greatly restricted.
At present, there are two main types of mechanized pulse diagnosis devices. The first is a large pulse diagnosis device used in professional places such as hospitals, and the device has a complex structure and a high use threshold, and can acquire a good pulse signal only by the accompanying guidance of professional medical care personnel, so that the device is difficult to adapt to the convenient development trend of modern medical treatment and is not beneficial to wide popularization. The second is a portable household pulse diagnosis instrument, which is convenient to use and relatively random in use scenes, but has high purchase cost, does not visually present the collected human body pulse distribution signals, and cannot give specific analysis principles and corresponding relations of the pulse of a user.
The main component of the mechanized pulse diagnosis equipment is a pulse condition sensor. Currently, pulse condition sensors include single point pulse condition sensors and array pulse condition sensors. The single-point pulse condition sensor only collects pulse signals at the radial artery in a single point mode, and judges the pulse condition of a human body by analyzing two-dimensional pulse signals through a time domain analysis method. The arrangement of each unit sensor in the existing array pulse condition sensor is scattered, and the positioning is not reasonably carried out according to the position of the cun, the chi and the guan of the radial artery of a human body, so that three-dimensional pulse condition signals can be collected, but the disordered signal distribution is not beneficial to the pulse condition signal analysis. Furthermore, most of the existing pulse condition sensor arrays are based on a silicon-based hard circuit board, and each sensor unit device is also made of a rigid material, so that the curved surface fitting degree of the wrist of a patient is poor, the acquisition accuracy can be influenced, and the wearing comfort is low
Therefore, in order to solve the above technical problems, it is necessary to provide a pulse detecting system based on a flexible array sensor, which is convenient to use and easy to wear, and can visually present pulse distribution, and a manufacturing method of the flexible array sensor for the pulse detecting system.
Disclosure of Invention
In view of this, in the embodiment of the present invention, to solve the problems that the large-scale diagnostic apparatus in the prior art is inconvenient to use, the portable diagnostic apparatus is inconvenient to wear, and the pulse condition distribution cannot be visually represented, the flexible array sensor is adopted to detect pulse signals of three radial arteries at multiple points, the detected pulse signals are analyzed by the processor, and the analysis result is three-dimensionally displayed by the determination system. Furthermore, the flexible array sensor adopted in the embodiment of the invention can reasonably distribute the sensor units according to the cun, the chi and the guan of the radial artery of the human body, and the flexible substrate and the flexible electrode are adopted, so that the accuracy of sensing signals is improved, and the wearing comfort level is improved.
In order to achieve the above object, an embodiment of the present invention provides the following technical solutions: a pulse condition detection system based on a flexible array sensor comprises: the external force application module is used for simulating the application of pressure to the radial artery in the pulse feeling process of the traditional Chinese medicine; the flexible array sensor is positioned at a preset position of a radial artery and used for sensing pulse pressure at the preset position; the signal processing module is connected with the output end of the flexible array sensor and used for processing the output signal of the flexible array sensor; the pulse condition acquisition module is connected with the signal processing module and is used for realizing the conversion and storage of signals; and the pulse condition distinguishing module is connected with the pulse condition acquisition module and is used for carrying out feature extraction and analysis according to the signals in the pulse condition acquisition module and realizing three-dimensional presentation of pulse conditions and distinguishing different pulse conditions.
As a further improvement of the present invention, the external force applying module includes: the flexible unit is positioned at a preset position of the radial artery and used for applying pressure to the radial artery in the process of simulating pulse feeling in traditional Chinese medicine; a fastening unit for fixing the flexible unit at a preset position of the radial artery; the pressurizing unit is connected with the flexible unit and is used for transforming the pressure in the flexible unit; and the air pressure detection unit is connected with the flexible unit and used for detecting the pressure in the flexible unit.
As a further improvement of the invention, the flexible array sensor is attached to the inner side of the flexible unit and used for sensing the pulse pressure at a preset position.
As a further improvement of the invention, the preset positions comprise the positions of the cun, the ulnar and the guan of the radial artery.
As a further development of the invention, the flexible array sensor comprises a plurality of pressure sensitive sensor units.
As a further improvement of the invention, the flexible array sensor comprises a flexible substrate, a pulse condition detection layer, a flexible electrode and an encapsulation layer, wherein the pulse condition detection layer comprises a plurality of pressure-sensitive sensor units.
As a further improvement of the present invention, the signal processing module includes a differential amplifying circuit and a filter circuit.
As a further improvement of the invention, the pulse condition acquisition module is a multi-channel data acquisition card and is used for converting an analog signal into a digital signal.
As a further improvement of the invention, the discrimination algorithm in the pulse condition discrimination module comprises the following steps: extracting the characteristics of the signals input by the pulse condition acquisition module, and judging the frequency, the intensity and the pulse condition of the pulse according to the extracted characteristics; drawing the pulse condition into a three-dimensional curved surface diagram in spatial distribution by adopting a difference method; and performing characteristic analysis on the curved surface, and determining the health condition of the human body by combining the frequency and the intensity of the pulse.
The embodiment of the invention also provides a manufacturing method of the flexible array sensor for the pulse condition detection system, which comprises the following steps: designing the position layout of each sensor unit in the flexible array sensor according to the distribution sizes of the cun, guan and chi parts of the radial artery of the human body; respectively preparing a flexible substrate with sensor units and a flexible electrode according to the designed position layout of the sensor units, preparing a flexible effective layer on the flexible substrate, and attaching an insulating layer on the flexible electrode; and attaching the flexible electrode and the flexible substrate by an attaching method.
The invention has the following advantages:
the embodiment of the invention adopts the flexible array sensor to detect pulse signals of three parts of the radial artery at multiple points respectively, analyzes the detected pulse signals through the processor and displays the analysis result in a three-dimensional manner through the judgment system. Furthermore, the flexible array sensor manufactured by the manufacturing method provided by the embodiment of the invention can reasonably distribute the sensor units according to the size, the size and the closing of the radial artery of the human body, and the flexible substrate and the flexible electrode are adopted, so that the accuracy of sensing signals is improved, and the wearing comfort level is improved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments described in the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a pulse detecting system based on a flexible array sensor according to an embodiment of the present invention;
fig. 2 is a schematic diagram of a distribution of sensing units of a flexible array sensor according to an embodiment of the present invention;
fig. 3 is a schematic flow chart and a corresponding schematic structural diagram of a manufacturing method of a flexible array sensor according to an embodiment of the present invention;
FIG. 4 is a schematic diagram of pulse signals detected by a flexible array sensor according to the embodiment shown in FIG. 1;
FIG. 5 is a schematic diagram of the spatial pulse profile sensed by the pulse detection system in the embodiment shown in FIG. 1;
FIG. 6 is a flowchart illustrating the operation steps of the pulse detecting system of the embodiment shown in FIG. 1.
Description of the reference symbols in the drawings:
100. pulse condition detection system based on flexible array sensor
10. Radial artery 21, pressurizing unit
23. Flexible unit 31 and flexible array sensor
33. Flexible substrate 40 and signal processing module
50. Pulse condition acquisition unit 60 and pulse condition discrimination unit
35. Data connector
Detailed Description
In order to make those skilled in the art better understand the technical solution of the present invention, the technical solution in the embodiment of the present invention will be clearly and completely described below with reference to the drawings in the embodiment of the present invention, and it is obvious that the described embodiment is only a part of the embodiment of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, a pulse detecting system 100 based on a flexible array sensor is provided in an embodiment of the present invention. The pulse condition detection system 100 based on the flexible array sensor comprises an external force applying module for applying pressure to the radial artery 10 in the process of simulating the pulse feeling of the traditional Chinese medicine, the flexible array sensor 31 which is positioned at the preset position of the radial artery 10 and used for sensing the pulse pressure at the preset position, a signal processing module 40 which is connected with the output end of the flexible array sensor 31 and used for processing the output signal of the flexible array sensor, a pulse condition collecting module 50 which is connected with the signal processing module 40 and used for realizing the conversion and storage of signals, and a pulse condition distinguishing module 60 which is connected with the pulse condition collecting module 50 and used for carrying out feature extraction and analysis according to the signals in the pulse condition collecting module 50 and realizing the three-dimensional presentation and distinguishing of different pulse conditions. Wherein the preset positions comprise the position of the cun, the ulnar and the guan of the radial artery.
With continued reference to fig. 1, the external force applying module includes a flexible unit 23 located at a preset position of the radial artery 10 and used for applying pressure to the radial artery 10 in a process of simulating a traditional Chinese medicine pulse-taking process, a fastening unit (not shown in the figure) for fixing the flexible unit 23 at the preset position of the radial artery 10, a pressurizing unit 21 connected to the flexible unit 23 and used for transforming the pressure in the flexible unit 23, and an air pressure detecting unit (not shown in the figure) connected to the flexible unit 23 and used for detecting the pressure in the flexible unit 23. The flexible array sensor 31 is attached to the inner side of the flexible unit 23 for sensing the pulse pressure at a predetermined position. In a specific embodiment, the flexible unit 23 is a flexible airbag, the fastening unit is a hook and loop fastener, the pressurizing unit 21 is an air pump, and the air pressure detecting unit is an air pressure sensor. Because the flexible air bag is completely flexible, the flexible air bag can be well attached to the wrist of a patient. The magic tape fixes the flexible air bag at a preset position in a surrounding manner, and the air pump is used for pressurizing and simulating different pulse feeling pressures of floating, middle and sinking in the pulse feeling process of the traditional Chinese medicine, so that the optimal pressure in the pulse feeling process can be determined, and the flexible array sensor 31 can acquire the pulse wave with the optimal waveform. The external force application module is simple in structure and easy to use.
Referring to fig. 1 and 2, the flexible array sensor 31 includes a plurality of pressure sensitive sensor units. The flexible array sensor 31 comprises a flexible substrate 33, a pulse condition detection layer, a flexible electrode and an encapsulation layer. Wherein the pulse detecting layer comprises a plurality of pressure-sensitive sensor units. The flexible array sensor 31 adopts a flexible design, can be perfectly attached to the curved surface of the wrist of a human body, and integrates sensor units at the three positions of size, dimension and closing into a flexible circuit, thereby effectively improving the use convenience. 3 sensor units are respectively distributed at the inch, the off and the ruler in the radial direction and the transverse direction and are used for detecting pulse width signals and pulse signals.
With continued reference to fig. 3, a method of making a flexible array sensor 31 for use in a pulse detection system includes the steps of: and designing the position layout of each sensor unit in the flexible array sensor according to the distribution sizes of the cun, guan and chi parts of the radial artery of the human body. Respectively preparing a flexible substrate with sensor units and a flexible electrode according to the designed position layout of the sensor units, preparing a flexible effective layer on the flexible substrate, and pasting an insulating layer on the flexible electrode. And attaching the flexible electrode and the flexible substrate by an attaching method.
The specific embodiment process is that 9 pressure-sensitive sensor units are distributed in a space with the length of 30mm and the width of 6mm, the interval between the axial pressure-sensitive sensor units is 10mm and is respectively used for detecting pulse signals of the cun position, the guan position and the chi position of a radial artery, the interval between the pressure-sensitive sensor units distributed in the radial direction is 1mm and is used for detecting pulse width signals, a stainless steel die is processed according to the design, and a flexible electrode is prepared on PET by a screen printing method. The Eco-flex prepolymer was dropped into a stainless steel mold, heated on a heating table, and removed after curing to serve as the flexible substrate 33 of the pulse condition sensor. Adding 0.5-2% of initiator Ammonium Persulfate (APS) and 1.5-3.5% of ethanol solution of monodisperse silicon dioxide microspheres into ionic liquid (1-vinyl-3-ethylimidazole dinitrile amine salt). And (3) putting the mixed solution into a centrifuge tube, uniformly mixing for 20 minutes, dripping into the prepared flexible substrate 33, putting on a heating table, heating to 70 ℃ for 40 minutes, and taking down after curing. After washing the ionic gel with a potassium hydroxide solution for 5 minutes, the ionic gel film was washed again with deionized water for 2 minutes and air-dried. The flexible electrode is attached to the flexible substrate 33 by means of an attachment method, and 502 glue is matched to ensure good contact. The flexible circuit is connected with the signal processing module 40 by a data connector 35. The data connector 35 may in particular be a standard plug, for example a 12P-XH2.54 standard plug, so that the array sensor is easily replaceable.
The flexible array sensor adopted by the embodiment of the invention can reasonably distribute the sensor units according to the cun, the chi and the guan of the radial artery of the human body, and the flexible substrate and the flexible electrode are adopted, so that the accuracy of sensing signals is improved, and the wearing comfort level is improved.
The signal processing module 40 includes a differential amplifying circuit and a filtering circuit. The signal processing module 40 converts the resistance signal of the pressure sensitive sensor unit into a voltage signal using a voltage division principle. Because the pulse signal changes weakly, the signal processing module 40 needs to amplify the voltage signal after the differential amplification circuit for a second time and add a band-pass filter to filter out high-frequency noise, and then transmit the signal to the pulse acquisition module 50. As shown in fig. 4, a schematic diagram of the pulse signal detected by the signal processing module 40 based on the flexible array sensor in one embodiment is shown.
The pulse acquisition module 50 is a multi-channel data acquisition card for converting analog signals into digital signals. The pulse condition acquisition module converts the analog quantity input by the signal processing module 40 into a digital quantity at a preset frequency, for example, at a specific frequency of 100 Hz.
The pulse condition distinguishing module 60 is used for performing feature extraction and analysis according to the signals in the pulse condition collecting module 50 and realizing three-dimensional presentation of pulse conditions and distinguishing different pulse conditions. The pulse condition determining module 60 may be a general-purpose computer or a specialized device for determining pulse condition signals. The discriminating algorithm in the pulse condition discriminating module 60 includes the steps of: extracting the characteristics of the signals input by the pulse condition acquisition module 50, and judging the frequency, the intensity and the pulse condition of the pulse according to the extracted characteristics; drawing the pulse condition into a three-dimensional curved surface diagram in spatial distribution by adopting a difference method; and performing characteristic analysis on the curved surface, and determining the health condition of the human body by combining the frequency and the intensity of the pulse. As shown in FIG. 5, the pulse detection system 100 in one embodiment is configured to detect a spatial pulse profile.
In one embodiment, the pulse condition acquisition module 50 may employ a multi-channel NI data acquisition card, and the software includes a DAQmx VI acquisition function packaged in the LABVIEW for implementing simultaneous acquisition and storage of multi-channel voltage signals. The two-dimensional pulse signal and the three-dimensional distribution curve of the pulse condition are displayed on the program interface of the pulse condition judging module 60.
As shown in fig. 6, a specific workflow of a pulse detecting system 100 based on a flexible array sensor according to an embodiment of the present invention is as follows: fixing an external force application module at a preset position (namely positioning the flexible array sensor), and applying pressure to simulate a pulse feeling process; the signal processing module receives a detection signal of the flexible array sensor and converts, amplifies and filters the signal, and the pulse condition acquisition module acquires and stores the signal output by the signal processing module through multiple channels; the pulse condition distinguishing unit extracts micro signal characteristics of the multi-channel collected signals of the pulse condition collecting module and performs pulse space interpolation distribution and analysis, thereby realizing three-dimensional presentation of pulse condition space distribution and distinguishing of different pulse conditions.
In the pulse condition detection system based on the flexible array sensor provided by the embodiment of the invention, the array sensor adopts a completely flexible design, can be perfectly attached to the curved surface of the wrist of a human body, integrates the sensing unit devices at the inch part, the close part and the size part into a flexible circuit, and improves the use convenience. And a plurality of sensor units are distributed at the inch, the close and the scale parts and are used for detecting pulse width signals. The pulse condition distinguishing module is not limited to the analysis of two-dimensional pulse condition signals, and the pulse condition signals are obtained by combining the difference of three-dimensional space distribution pulse condition signals for feature extraction and analysis. The flexible array sensor provided by the embodiment of the invention has the advantages of simple preparation, low cost, strong biocompatibility and easy replacement, and the pulse condition detection system breaks through the traditional two-dimensional pulse condition characteristic point analysis and analyzes the pulse condition from the angle of a three-dimensional curved surface to judge the human body pulse condition, thereby having good application prospect in the modernized Chinese medical science city.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.

Claims (10)

1. A pulse detection system based on a flexible array sensor, the system comprising:
the external force application module is used for simulating the application of pressure to the radial artery in the pulse feeling process of the traditional Chinese medicine;
the flexible array sensor is positioned at a preset position of a radial artery and used for sensing pulse pressure at the preset position;
the signal processing module is connected with the output end of the flexible array sensor and used for processing the output signal of the flexible array sensor;
the pulse condition acquisition module is connected with the signal processing module and is used for realizing the conversion and storage of signals;
and the pulse condition distinguishing module is connected with the pulse condition acquisition module and is used for carrying out feature extraction and analysis according to the signals in the pulse condition acquisition module and realizing three-dimensional presentation of pulse conditions and distinguishing different pulse conditions.
2. The pulse detecting system based on the flexible array sensor as claimed in claim 1, wherein the external force applying module comprises:
the flexible unit is positioned at a preset position of the radial artery and used for applying pressure to the radial artery in the process of simulating pulse feeling in traditional Chinese medicine;
a fastening unit for fixing the flexible unit at a preset position of the radial artery;
the pressurizing unit is connected with the flexible unit and is used for transforming the pressure in the flexible unit;
and the air pressure detection unit is connected with the flexible unit and used for detecting the pressure in the flexible unit.
3. The pulse detecting system of claim 2, wherein the flexible array sensor is attached to the inner side of the flexible unit for sensing the pulse pressure at a predetermined position.
4. The pulse detecting system based on the flexible array sensor as claimed in claim 1, wherein the predetermined positions include the position of the radial artery at the cun, chi and guan positions.
5. The pulse detecting system based on the flexible array sensor as claimed in claim 1, wherein the flexible array sensor comprises a plurality of pressure sensitive sensor units.
6. The pulse detecting system based on the flexible array sensor as claimed in claim 5, wherein the flexible array sensor comprises a flexible substrate, a pulse detecting layer, a flexible electrode and an encapsulating layer, and the pulse detecting layer comprises a plurality of pressure-sensitive sensor units.
7. The pulse condition detection system based on the flexible array sensor as claimed in claim 1, wherein the signal processing module comprises a differential amplifying circuit and a filtering circuit.
8. The pulse detection system of claim 1, wherein the pulse acquisition module is a multi-channel data acquisition card for converting analog signals into digital signals.
9. The pulse detecting system based on the flexible array sensor as claimed in claim 1, wherein the discriminating algorithm in the pulse discriminating module comprises the steps of:
extracting the characteristics of the signals input by the pulse condition acquisition module, and judging the frequency, the intensity and the pulse condition of the pulse according to the extracted characteristics;
drawing the pulse condition into a three-dimensional curved surface diagram in spatial distribution by adopting a difference method;
and performing characteristic analysis on the curved surface, and determining the health condition of the human body by combining the frequency and the intensity of the pulse.
10. A method for manufacturing a flexible array sensor for use in a pulse detection system, the method comprising the steps of:
designing the position layout of each sensor unit in the flexible array sensor according to the distribution sizes of the cun, guan and chi parts of the radial artery of the human body;
respectively preparing a flexible substrate with sensor units and a flexible electrode according to the designed position layout of the sensor units, preparing a flexible effective layer on the flexible substrate, and attaching an insulating layer on the flexible electrode;
and attaching the flexible electrode and the flexible substrate by an attaching method.
CN201911172242.8A 2019-11-26 2019-11-26 Manufacturing method of flexible array sensor and pulse condition detection system based on flexible array sensor Pending CN110840405A (en)

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CN111387954A (en) * 2020-03-24 2020-07-10 燕山大学 Multi-array pulse condition acquisition system
CN111938610A (en) * 2020-07-10 2020-11-17 中国科学院上海微系统与信息技术研究所 Air bag integrated pulse diagnosis instrument touch sensing array structure
CN112263222A (en) * 2020-11-13 2021-01-26 电子科技大学 Feedback enhanced pulse condition searching and collecting array and method
CN113397500A (en) * 2021-08-03 2021-09-17 华东师范大学 Pulse monitoring device
CN114869234A (en) * 2022-04-29 2022-08-09 无锡市华焯光电科技有限公司 Pulse data detection device and detection system with same

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