CN114720189A - Integral type ration sampling adds reagent device - Google Patents
Integral type ration sampling adds reagent device Download PDFInfo
- Publication number
- CN114720189A CN114720189A CN202210177061.XA CN202210177061A CN114720189A CN 114720189 A CN114720189 A CN 114720189A CN 202210177061 A CN202210177061 A CN 202210177061A CN 114720189 A CN114720189 A CN 114720189A
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- Prior art keywords
- sampling
- rod
- support rod
- guide
- motor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
- G01N2001/1418—Depression, aspiration
- G01N2001/1427—Positive displacement, piston, peristaltic
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- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Hydrology & Water Resources (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
The invention discloses an integrated quantitative sampling reagent adding device which comprises an operation table, a mechanical arm, a sampling mechanism, a sampling cup, a mixing cup and a cleaning chamber, wherein the mechanical arm, the sampling cup, the mixing cup and the cleaning chamber are arranged on the operation table, the sampling mechanism is arranged at the end part of the mechanical arm and comprises an installation table, a sampling tube, a piston and a sampling assembly, the sampling assembly comprises a first supporting rod, a second supporting rod, a first motor, a first screw rod, a first guide sleeve and a second guide sleeve, when sampling is carried out, the mechanical arm places the sampling mechanism above the sampling cup, the sampling tube extends into the sampling cup, the first motor is started, the first screw rod is driven to rotate, the piston is driven to move upwards along the first guide rod, and blood can be quantitatively sampled according to the number of turns of the first screw rod driven to rotate by the motor.
Description
Technical Field
The invention relates to the technical field of sampling, in particular to an integrated quantitative sampling and reagent adding device.
Background
At present, 500uL of diluent is added into a reaction cup, then 2uL of the diluent is sampled by using a liquid transfer device, the sample is added into the reaction cup after sampling, the reaction cup is shaken to uniformly mix the sample and the diluent, and a liquid transfer device with a 50uL or 100uL range needs to be replaced, 50uL of reagent is added, and then the mixture is uniformly mixed for detection. Whole operation process need use two pipettors of different ranges at least, and operation process is more complicated, and especially to sample error great below 2uL, the cost is higher, and is comparatively troublesome, and the blood after the sample is easily received environmental pollution moreover, causes the testing result inaccurate.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention aims to provide an integrated quantitative sampling and reagent adding device.
In order to achieve the technical purpose, the technical scheme adopted by the invention is as follows.
An integrated quantitative sampling and reagent adding device, comprising:
the manipulator, the sampling cup, the mixing cup and the cleaning chamber are arranged on the operation table, the sampling mechanism is arranged at the end part of the manipulator and comprises an installation table, a sampling tube, a piston and a sampling assembly, the installation table is connected to the end part of the manipulator, the sampling tube is sleeved in the installation table, the bottom of the sampling tube penetrates through the bottom of the installation table, the piston is arranged in the sampling tube in a matching manner, the sampling assembly comprises a first support rod, a second support rod, a first motor, a first screw rod, a first guide sleeve and a second guide sleeve, the first support rod and the second support rod are vertically arranged at the top of the installation table, the first guide sleeve and the second guide sleeve are vertically arranged at the top of the piston, the first motor is arranged at the top of the first support rod, and an output shaft of the first motor is vertically downward, the first screw rod is coaxially and fixedly connected to the output shaft end of the first motor, the first screw rod is sleeved in the first guide sleeve, the first guide rod is arranged on one side of the second support rod in parallel, and the second guide rod is sleeved in the second guide sleeve.
As a further improvement of the technical scheme, a blocking component is arranged at the bottom of the mounting table and comprises a connecting plate, a pull rope, a baffle and a connecting column, the connecting plate is vertically arranged at the bottom of the mounting table, one end of the connecting column is connected with the end part of the baffle, the other end of the connecting column horizontally penetrates through the connecting plate, an external step is arranged at the end part of the connecting column, the baffle is positioned below the connecting column, a first spring is sleeved on the connecting column, one end of the first spring is abutted against the end part of the baffle, the other end of the first spring is abutted against the connecting plate, the top surface of the baffle is matched with the bottom of the sampling tube to block the sampling tube, a first guide pillar and a second guide pillar are horizontally connected with the top of the mounting table, a third support rod and a fourth support rod are respectively sleeved on the first guide pillar and the second guide pillar, a second spring is sleeved on the first guide pillar and the fourth guide pillar, and a shifting block is connected between the third support rod and the fourth support rod, the top of the mounting table is provided with a guide rail which forms sliding fit with the shifting block, the bottom surface of the shifting block is obliquely arranged, the top surface of the piston is in contact with the bottom inclined surface of the shifting block in the process that the piston moves upwards, and a pull rope is connected between the baffle and the shifting block.
As a further improvement of the technical scheme, the third support rod and the fourth support rod are provided with adjusting assemblies, each adjusting assembly comprises a second motor, a second lead screw and a second guide rod, the second motor is installed at the top of the third support rod, an output shaft of the second motor is vertically downward, the top end of the second lead screw is coaxially and fixedly connected with the output shaft end of the second motor, the other end of the second lead screw is movably connected with the bottom of the third support rod, the second guide rod is vertically arranged on one side of the fourth support rod, and the second lead screw and the second guide rod are sleeved with the shifting block.
As a further improvement of the technical scheme, a liquid feeding assembly is arranged on the mounting table and comprises a connecting shell and a liquid feeding pipe, the connecting shell is communicated with the liquid feeding pipe, and the discharge end of the liquid feeding pipe penetrates through the piston to extend into the sampling pipe.
As a further improvement of the technical scheme, a shifting wheel is arranged in the connecting shell, the end part of the shifting wheel is connected with a connecting shaft, and centrifugal rods are uniformly arranged on the connecting shaft in a surrounding manner in the circumferential direction.
Compared with the prior art, the sampling tube has the advantages that in the using process of the sampling tube, the blood can be quantitatively sampled when the sampling tube is used for sampling, the sampling tube can be plugged when the liquid is taken to be quantitative, so that the sampling tube is prevented from being polluted, the bottom of the sampling tube can be plugged under different sampling amounts, and the solution in the sampling tube can be triggered to oscillate when the dissolving agent is added, so that the dissolving speed of the blood is increased.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required to be used in the embodiments of the present invention will be briefly described below. It is obvious that the drawings described below are only some embodiments of the invention, and that for a person skilled in the art, other drawings can be derived from them without inventive effort.
Fig. 1 is a schematic view of the overall structure of the present invention.
FIG. 2 is a schematic view of a sampling assembly of the present invention.
Fig. 3 is a schematic view of the piston installation of the present invention.
Fig. 4 is a schematic view of a charging assembly of the present invention.
Fig. 5 is a schematic view of the transmission mechanism of the present invention.
FIG. 6 is a diagram of a shift block structure according to the present invention.
Fig. 7 is a schematic view of the installation of the shift block of the present invention.
Fig. 8 is a schematic view of the baffle installation of the present invention.
The indications in the figures are:
1. an operation table; 2. a manipulator; 3. a sampling mechanism; 4. sampling a cup; 5. a mixing cup; 6. a cleaning chamber; 7. an installation table; 8. a sampling tube; 9. a piston; 10. a sampling assembly; 11. a transmission mechanism; 12. a liquid adding assembly; 13. a first supporting rod; 14. a second supporting rod; 15. a first motor; 16. a first screw rod; 17. a first guide rod; 18. a first guide sleeve; 19. a second guide sleeve; 20. connecting the shell; 21. a liquid feeding pipe; 22. a connecting shaft; 23. a centrifugal lever; 24. a first guide post; 25. a second guide post; 26. a third supporting rod; 27. a fourth supporting rod; 28. a second motor; 29. a second screw rod; 30, a second guide rod; 31. a shift block; 32. a guide rail; 33. a connecting plate; 34. pulling a rope; 35. a baffle plate; 36. connecting columns.
Detailed Description
The technical scheme of the invention is further explained by the specific implementation mode in combination with the attached drawings.
Wherein the showings are for the purpose of illustration only and are shown by way of illustration only and not in actual form, and are not to be construed as limiting the present patent; to better illustrate the embodiments of the present invention, some parts of the drawings may be omitted, enlarged or reduced, and do not represent the size of an actual product; it will be understood by those skilled in the art that certain well-known structures in the drawings and descriptions thereof may be omitted.
The same or similar reference numerals in the drawings of the embodiments of the present invention correspond to the same or similar components; in the description of the present invention, it should be understood that if the terms "upper", "lower", "left", "right", "inner", "outer", etc. are used for indicating the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, it is only for convenience of description and simplification of description, but it is not indicated or implied that the referred device or element must have a specific orientation, be constructed in a specific orientation and be operated, and therefore, the terms describing the positional relationship in the drawings are only used for illustrative purposes and are not to be construed as limitations of the present patent, and the specific meanings of the terms may be understood by those skilled in the art according to specific situations.
In the description of the present invention, unless otherwise explicitly specified or limited, the term "connected" or the like, if appearing to indicate a connection relationship between components, is to be understood broadly, for example, as being either fixedly connected, detachably connected, or integrated; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or may be connected through one or more other components or may be in an interactive relationship with one another. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
1-8, an integrated quantitative sampling and reagent adding device, comprising:
operation panel 1, manipulator 2, sampling mechanism 3, sample cup 4, mix cup 5, purge chamber 6, manipulator 2, sample cup 4, mix cup 5, purge chamber 6 set up on operation panel 1, sampling mechanism 3 set up in the tip of manipulator 2, sampling mechanism 3 include mount table 7, sampling tube 8, piston 9, sampling subassembly 10, mount table 7 connect in the tip of manipulator 2, sampling tube 8 cover locate in mount table 7, the bottom of mount table 7 is passed to the bottom of sampling tube 8, piston 9 match and set up in sampling tube 8, sampling subassembly 10 include bracing piece one 13, bracing piece two 14, motor one 15, lead screw one 16, guide arm one 17, guide pin bushing one 18, guide pin bushing two 19, bracing piece one 13, support bar two 14 vertically set up in the top of mount table 7, guide pin bushing one 18, The second guide sleeve 19 is vertically arranged at the top of the piston 9, the first motor 15 is arranged at the top of the first support rod 13, an output shaft of the first motor 15 is vertically downward, the first screw rod 16 is coaxially and fixedly connected to an output shaft end of the first motor 15, the first screw rod 16 is sleeved in the first guide sleeve 18, the first guide rod 17 is arranged on one side of the second support rod 14 in parallel, the first guide rod 17 is sleeved in the second guide sleeve 19, when sampling is carried out, the sampling mechanism 3 is placed above the sampling cup 4 by the manipulator 2, then the sampling tube 8 extends into the sampling cup 4, the first motor 15 is started, and the first screw rod 16 is driven to rotate, so that the piston 9 is driven to move upwards along the first guide rod 17, and blood can be quantitatively sampled according to the number of rotating turns of the first screw rod 16 driven by the first motor 15.
More specifically, after blood is sampled and in order to avoid sampling pollution, a blocking assembly is arranged at the bottom of the mounting table 7 and comprises a connecting plate 33, a pull rope 34, a baffle 35 and a connecting column 36, the connecting plate 33 is vertically arranged at the bottom of the mounting table 7, one end of the connecting column 36 is connected with the end of the baffle 35, the other end of the connecting column 36 horizontally penetrates through the connecting plate 33, an external step is arranged at the end of the connecting column 36, the baffle 35 is located below the connecting column 36, a first spring is sleeved on the connecting column 36, one end of the first spring abuts against the end of the baffle 35, the other end of the first spring abuts against the connecting plate 33, the top surface of the baffle 35 is matched with the bottom of the sampling tube 8 and can block the sampling tube 8, a first guide pillar 24 and a second guide pillar 25 are horizontally connected to the top of the mounting table 7, and a third support rod 26 is sleeved on the first guide pillar 24 and the second guide pillar 25 respectively, A fourth support rod 27, a second spring is sleeved on the first guide pillar 24 and the second guide pillar 25, a displacement block 31 is connected between the third support rod 26 and the fourth support rod 27, a guide rail 32 which forms a sliding fit with the displacement block 31 is arranged at the top of the mounting table 7, the bottom surface of the displacement block 31 is arranged in an inclined manner, in the process that the piston 9 moves upwards, the top surface of the piston 9 is in contact with the bottom inclined surface of the displacement block 31, a pull rope 34 is connected between the baffle 35 and the displacement block 31, when the liquid is taken to a fixed amount, the piston 9 abuts against the bottom surface of the displacement block 31, so that the displacement block 31 moves along the first guide pillar 24 and the second guide pillar 25, the pull rope 34 is driven to pull the baffle 35 to move towards the bottom close to the sampling tube 8, and the sampling tube 8 is blocked.
More specifically, in order to satisfy and carry out the shutoff to the bottom of sampling tube 8 under the different sampling volume, bracing piece three 26, bracing piece four 27 on be provided with adjusting part, adjusting part includes motor two 28, lead screw two 29, guide bar two 30, motor two 28 is installed in the top of bracing piece three 26, the output shaft of motor two 28 is vertical downwards, the top of lead screw two 29 and the coaxial fixed connection of output shaft end of motor two 28, the bottom swing joint of the other end and bracing piece three 26, guide bar two 30 vertically set up in one side of bracing piece four 27, shift block 31 cover is located on lead screw two 29, guide bar two 30, motor two 28 drive lead screw two 29 rotate, can adjust the distance between shift block 31 and the piston 9 to can satisfy and realize carrying out the shutoff to the bottom of sampling tube 8 under the different sampling volume.
As shown in fig. 4, need discharge blood after the sample is accomplished, need mix the washing to sampling tube 8 simultaneously, for this reason, be provided with liquid feeding subassembly 12 on mount table 7, liquid feeding subassembly 12 is including connecting casing 20, liquid feeding pipe 21, connects casing 20 and communicates on liquid feeding pipe 21, and the discharge end of liquid feeding pipe 21 passes piston 9 and stretches into to sampling tube 8 in to be convenient for extract the lytic agent.
More specifically, a dial wheel is arranged in the connecting shell 20, the end of the dial wheel is connected with a connecting shaft 22, centrifugal rods 23 are uniformly arranged on the connecting shaft 22 in a surrounding manner in the circumferential direction, when the lytic agent is extracted, the lytic agent impacts the dial wheel to drive the connecting shaft 22 to rotate, so that the centrifugal rods 23 rotate and extend, the end of the centrifugal rods 23 touches the mounting table 7, so that the solution in the sampling tube 8 oscillates, and the dissolving speed of blood is increased.
The working principle is as follows:
in the using process of the sampling device, when sampling is carried out, the mechanical arm 2 places the sampling mechanism 3 above the sampling cup 4, then the sampling tube 8 extends into the sampling cup 4, the motor I15 is started, so that the screw rod I16 is driven to rotate, the piston 9 is driven to move upwards along the guide rod I17, blood can be quantitatively sampled according to the number of turns of the rotation of the screw rod I16 driven by the motor I15, when liquid is taken to be quantitative, the piston 9 props against the bottom surface of the shifting block 31, so that the shifting block 31 moves along the guide post I24 and the guide post II 25, the pull rope 34 is driven to pull the baffle 35 to move towards the bottom close to the sampling tube 8, so that the sampling tube 8 is plugged, the motor II 28 drives the screw rod II 29 to rotate, the distance between the shifting block 31 and the piston 9 can be adjusted, so that the plugging of the bottom of the sampling tube 8 can be realized under different sampling quantities, when a dissolving agent is extracted, the dissolving agent impacts the dial wheel to drive the connecting shaft 22 to rotate, so that the centrifugal rod 23 rotates and extends, the end part of the centrifugal rod 23 touches the mounting platform 7, the solution in the sampling tube 8 is oscillated, and the dissolving speed of the blood is improved.
It should be understood that the above-described embodiments are merely preferred embodiments of the invention and the technical principles applied thereto. It will be understood by those skilled in the art that various modifications, equivalents, changes, and the like can be made to the present invention. However, such variations are within the scope of the invention as long as they do not depart from the spirit of the invention. In addition, certain terms used in the specification and claims of the present application are not limiting, but are used merely for convenience of description.
Claims (5)
1. An integrated quantitative sampling and reagent adding device, which is characterized by comprising:
the manipulator, the sampling cup, the mixing cup and the cleaning chamber are arranged on the operation table, the sampling mechanism is arranged at the end part of the manipulator and comprises an installation table, a sampling tube, a piston and a sampling assembly, the installation table is connected to the end part of the manipulator, the sampling tube is sleeved in the installation table, the bottom of the sampling tube penetrates through the bottom of the installation table, the piston is arranged in the sampling tube in a matching manner, the sampling assembly comprises a first support rod, a second support rod, a first motor, a first screw rod, a first guide sleeve and a second guide sleeve, the first support rod and the second support rod are vertically arranged at the top of the installation table, the first guide sleeve and the second guide sleeve are vertically arranged at the top of the piston, the first motor is arranged at the top of the first support rod, and an output shaft of the first motor is vertically downward, the first screw rod is coaxially and fixedly connected to the output shaft end of the first motor, the first screw rod is sleeved in the first guide sleeve, the first guide rod is arranged on one side of the second support rod in parallel, and the second guide rod is sleeved in the second guide sleeve.
2. The integrated quantitative sampling and reagent adding device according to claim 1, wherein a blocking component is arranged at the bottom of the mounting table and comprises a connecting plate, a pull rope, a baffle plate and a connecting column, the connecting plate is vertically arranged at the bottom of the mounting table, one end of the connecting column is connected with the end of the baffle plate, the other end of the connecting column horizontally penetrates through the connecting plate, an external step is arranged at the end of the connecting column, the baffle plate is arranged below the connecting column, a first spring is sleeved on the connecting column, one end of the first spring abuts against the end of the baffle plate, the other end of the first spring abuts against the connecting plate, the top surface of the baffle plate is matched with the bottom of the sampling tube to block the sampling tube, a first guide pillar and a second guide pillar are horizontally connected with the top of the mounting table, a third support rod and a fourth support rod are respectively sleeved on the first guide pillar and the second guide pillar, a second spring is sleeved on the first guide pillar and the second guide pillar, the piston is characterized in that a shifting block is connected between the third supporting rod and the fourth supporting rod, a guide rail which is in sliding fit with the shifting block is arranged at the top of the mounting table, the bottom surface of the shifting block is obliquely arranged, the top surface of the piston is in contact with the inclined surface of the bottom of the shifting block in the process of moving the piston upwards, and a pull rope is connected between the baffle and the shifting block.
3. The integrated quantitative sampling and reagent adding device of claim 2, wherein the third support rod and the fourth support rod are provided with adjusting assemblies, each adjusting assembly comprises a second motor, a second screw rod and a second guide rod, the second motor is mounted at the top of the third support rod, an output shaft of the second motor is vertically downward, the top end of the second screw rod is coaxially and fixedly connected with the output shaft end of the second motor, the other end of the second screw rod is movably connected with the bottom of the third support rod, the second guide rod is vertically arranged at one side of the fourth support rod, and the second screw rod and the second guide rod are sleeved with the shifting block.
4. The integrated quantitative sampling and reagent adding device according to claim 3, wherein the mounting table is provided with a liquid adding assembly, the liquid adding assembly comprises a connecting shell and a liquid adding pipe, the connecting shell is communicated with the liquid adding pipe, and a discharging end of the liquid adding pipe penetrates through the piston and extends into the sampling pipe.
5. The integrated quantitative sampling and reagent adding device according to claim 4, wherein a thumb wheel is arranged in the connecting shell, a connecting shaft is connected to the end of the thumb wheel, and centrifugal rods are uniformly arranged around the connecting shaft in the circumferential direction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210177061.XA CN114720189A (en) | 2022-02-25 | 2022-02-25 | Integral type ration sampling adds reagent device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210177061.XA CN114720189A (en) | 2022-02-25 | 2022-02-25 | Integral type ration sampling adds reagent device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114720189A true CN114720189A (en) | 2022-07-08 |
Family
ID=82235852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210177061.XA Withdrawn CN114720189A (en) | 2022-02-25 | 2022-02-25 | Integral type ration sampling adds reagent device |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114720189A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024066274A1 (en) * | 2022-09-29 | 2024-04-04 | 时新(上海)产品设计有限公司 | Sample adding device |
-
2022
- 2022-02-25 CN CN202210177061.XA patent/CN114720189A/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024066274A1 (en) * | 2022-09-29 | 2024-04-04 | 时新(上海)产品设计有限公司 | Sample adding device |
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| WW01 | Invention patent application withdrawn after publication | ||
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Application publication date: 20220708 |