CN114646757A - Sample analysis system, film reading equipment, unloading device and unloading method - Google Patents
Sample analysis system, film reading equipment, unloading device and unloading method Download PDFInfo
- Publication number
- CN114646757A CN114646757A CN202011543134.XA CN202011543134A CN114646757A CN 114646757 A CN114646757 A CN 114646757A CN 202011543134 A CN202011543134 A CN 202011543134A CN 114646757 A CN114646757 A CN 114646757A
- Authority
- CN
- China
- Prior art keywords
- unloading
- conveying
- feedback signal
- transmission
- controlling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004458 analytical method Methods 0.000 title claims abstract description 42
- 238000000034 method Methods 0.000 title claims abstract description 27
- 230000007246 mechanism Effects 0.000 claims abstract description 313
- 230000005540 biological transmission Effects 0.000 claims abstract description 120
- 238000001514 detection method Methods 0.000 claims abstract description 65
- 230000015654 memory Effects 0.000 claims abstract description 31
- 238000004590 computer program Methods 0.000 claims abstract description 20
- 238000012546 transfer Methods 0.000 claims description 81
- 239000008280 blood Substances 0.000 claims description 14
- 210000004369 blood Anatomy 0.000 claims description 14
- 238000003384 imaging method Methods 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 7
- 239000011248 coating agent Substances 0.000 claims description 6
- 238000000576 coating method Methods 0.000 claims description 6
- 230000011664 signaling Effects 0.000 claims description 6
- 238000010191 image analysis Methods 0.000 claims description 3
- 238000010586 diagram Methods 0.000 description 4
- 238000004891 communication Methods 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000012806 monitoring device Methods 0.000 description 2
- 238000010186 staining Methods 0.000 description 2
- 230000007723 transport mechanism Effects 0.000 description 2
- 238000003491 array Methods 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The embodiment of the application provides a sample analysis system, a slide reading device, an unloading device and an unloading method, wherein the unloading device comprises an unloading transmission mechanism, a driving mechanism and a detection mechanism, the unloading transmission mechanism is provided with a plurality of unloading transmission positions for transmitting slide baskets, the detection mechanism is used for detecting state information corresponding to the unloading transmission positions and generating corresponding feedback signals, and the driving mechanism is used for driving the unloading transmission mechanism; a memory for storing a computer program; and a processor for invoking the computer program in the memory to perform: receiving an unloading instruction; controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty; and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
Description
Technical Field
The application relates to the technical field of medical instruments, in particular to a sample analysis system, a piece reading device, an unloading device and an unloading method.
Background
The film reading equipment is instrument equipment which is used for carrying out image shooting and analysis on cells in a sample smeared on a smear to be tested, and realizing automatic loading and film reading of batch blood smears. The blood smear is usually placed in a slide basket, and the slide basket is transported to a corresponding unloading position by a transport mechanism for slide basket unloading, so that the smear device can analyze the blood smear stored in the slide basket.
Therefore, how to achieve effective unloading of the slide basket is a hot topic that those skilled in the art are studying.
Disclosure of Invention
The embodiments of the present application mainly aim at providing a sample analysis system, a slide reading device, an unloading device and an unloading method, and aim at realizing effective unloading of a slide basket.
In a first aspect, an embodiment of the present application provides a sample analysis system, including:
the blood analyzer is used for carrying out conventional blood detection on a sample to be detected;
the smear preparation device is used for preparing the sample to be detected into a smear and placing the smear into a slide basket;
the slide reading device comprises an unloading device for unloading the slide basket and a slide reading device for acquiring cell images in a sample to be detected smeared on the coating and analyzing the cell images; the unloading device comprises an unloading conveying mechanism, a driving mechanism and a detection mechanism, wherein the unloading conveying mechanism is provided with a plurality of unloading conveying positions for conveying the slide baskets, the detection mechanism is used for detecting state information corresponding to the unloading conveying positions and generating corresponding feedback signals, and the driving mechanism is used for driving the unloading conveying mechanism;
a memory for storing a computer program; and
a processor for invoking a computer program in the memory to perform:
receiving an unloading instruction;
controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty;
and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
In a second aspect, an embodiment of the application provides slide reading equipment, which includes an unloading device for unloading the slide basket, and a slide reading device for acquiring a cell image in a sample to be tested smeared on a coating and analyzing the cell image;
the unloading device comprises an unloading conveying mechanism, a driving mechanism and a detection mechanism, wherein the unloading conveying mechanism is provided with a plurality of unloading conveying positions for conveying the slide baskets, the detection mechanism is used for detecting state information corresponding to the unloading conveying positions and generating corresponding feedback signals, and the driving mechanism is used for driving the unloading conveying mechanism;
a memory for storing a computer program; and
a processor for invoking a computer program in the memory to perform:
receiving an unloading instruction;
controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty;
and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
In a third aspect, an embodiment of the present application provides an unloading device, where the unloading device includes an unloading and conveying mechanism, a driving mechanism, and a detection mechanism, where the unloading and conveying mechanism is provided with a plurality of unloading and conveying positions for conveying the slide baskets, the detection mechanism is configured to detect status information corresponding to the unloading and conveying positions and generate corresponding feedback signals, and the driving mechanism is configured to drive the unloading and conveying mechanism;
a memory for storing a computer program; and
a processor for invoking a computer program in the memory to perform:
receiving an unloading instruction;
controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty or not;
and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
In a fourth aspect, an embodiment of the present application provides a smear loading and unloading method, which is applied to an unloading device, where the unloading device includes an unloading and conveying mechanism, a driving mechanism, and a detection mechanism, the unloading and conveying mechanism is provided with a plurality of unloading and conveying positions for conveying the slide baskets, the detection mechanism is used to detect status information corresponding to the unloading and conveying positions and generate corresponding feedback signals, and the driving mechanism is used to drive the unloading and conveying mechanism;
the method comprises the following steps:
receiving an unloading instruction;
controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty;
and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
The embodiment of the application provides a sample analysis system, a piece reading device, an unloading device and an unloading method, wherein the sample analysis system comprises: the blood analyzer is used for carrying out conventional blood detection on a sample to be detected; the smear preparation device is used for preparing the sample to be detected into a smear and placing the smear into a slide basket; the slide reading device comprises an unloading device for unloading the slide basket and a slide reading device for acquiring cell images in a sample to be detected smeared on the coating and analyzing the cell images; the unloading device comprises an unloading conveying mechanism, a driving mechanism and a detection mechanism, wherein the unloading conveying mechanism is provided with a plurality of unloading conveying positions for conveying the slide baskets, the detection mechanism is used for detecting state information corresponding to the unloading conveying positions and generating corresponding feedback signals, and the driving mechanism is used for driving the unloading conveying mechanism; a memory for storing a computer program; and a processor for invoking the computer program in the memory to perform: receiving an unloading instruction; controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty or not; and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal. The unloading conveying mechanism is used for detecting the unloading conveying state information corresponding to the unloading conveying mechanism through the detection mechanism, generating a corresponding feedback signal according to a detection result, and controlling the driving mechanism to drive the unloading conveying mechanism to execute a corresponding unloading task by using the feedback signal, so that the unloading conveying mechanism can be fully utilized to unload and convey, and the effective unloading of the slide basket is realized.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the description below are some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a block diagram schematically illustrating a sample analysis system according to an embodiment of the present disclosure;
FIG. 2A is a block diagram schematically illustrating the construction of a smear preparation apparatus of the sample analysis system;
FIG. 2B is a block diagram schematically illustrating the structure of a slide reading apparatus of the specimen analysis system;
FIG. 3 is a block diagram schematically illustrating the structure of an unloading apparatus of the sample analysis system;
FIGS. 4A and 4B are schematic structural views of the unloading device;
FIG. 5 is a flowchart illustrating steps of an offloading method provided by an embodiment of the application;
fig. 6A-6D are schematic views of scenarios in which the offloading device performs corresponding offloading tasks.
Detailed Description
The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are some, but not all, embodiments of the present application. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
In the description of the present application, unless expressly stated or limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meaning of the above terms in the present application can be understood in a specific case by those of ordinary skill in the art.
The embodiment of the application provides a sample analysis system, a piece reading device, an unloading device and an unloading method, wherein the sample analysis system comprises: the blood analyzer is used for carrying out conventional blood detection on a sample to be detected; the smear preparation device is used for preparing the sample to be detected into a smear and placing the smear into a slide basket; the slide reading device comprises an unloading device for unloading the slide basket and a slide reading device for acquiring cell images in a sample to be detected smeared on the coating and analyzing the cell images; the unloading device comprises an unloading conveying mechanism, a driving mechanism and a detection mechanism, wherein the unloading conveying mechanism is provided with a plurality of unloading conveying positions for conveying the slide baskets, the detection mechanism is used for detecting state information corresponding to the unloading conveying positions and generating corresponding feedback signals, and the driving mechanism is used for driving the unloading conveying mechanism; a memory for storing a computer program; and a processor for invoking the computer program in the memory to perform: receiving an unloading instruction; controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty or not; and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal. The detection mechanism detects the state information of unloading transmission corresponding to the unloading transmission mechanism, corresponding feedback signals are generated according to detection results, and the feedback signals are used for controlling the driving mechanism to drive the unloading transmission mechanism to execute corresponding unloading tasks, so that the unloading transmission of the unloading transmission mechanism can be fully utilized, and the effective unloading of the slide basket is realized.
In the following, some embodiments of the present application will be described in detail with reference to the drawings, and features in the following examples and examples may be combined with each other without conflict.
Referring to fig. 1, an embodiment of the present application provides a sample analysis system 100 for performing detection analysis on a sample to be analyzed to obtain a corresponding detection result. The sample analysis system 100 includes a blood analyzer 10, a smear preparation apparatus 20, a slide reading apparatus 30, and a control device 40.
The blood analyzer 10 is used for performing routine blood tests on a sample to be tested.
The smear preparing apparatus 20 is used to make a smear of a sample to be tested, including but not limited to a blood sample, and place the smear into a smear placing slot of a smear basket.
The slide reading device 30 is used for image shooting and analysis detection of the cells in the slide so as to obtain the corresponding analysis result.
Specifically, the smear preparation apparatus 20 includes a sampling mechanism 201 for extracting a sample, a slide loading mechanism 202 for moving a slide to a work line, a loading mechanism 203 for loading a sample to a slide, a pushing mechanism 204 for flattening the sample on the slide to form a sample film, a drying mechanism 205 for drying the sample film on the slide, a staining mechanism 206 for staining the slide to make a smear, and a smear loading mechanism 207 for loading the finished smear to a slide basket, as shown in fig. 2A.
The slide reading device 30 comprises an unloading device 60 for unloading the slide basket, and a slide reading device 50 for acquiring cell images in the sample to be tested smeared on the smear and analyzing the cell images. The film reading device 50 comprises an imaging mechanism 501, a smear moving mechanism 502 and an image analysis mechanism 503. The imaging mechanism 501 is used for shooting the cells in the sample smeared on the smear, the smear moving mechanism 502 is used for carrying the smear and moving the smear relative to the imaging mechanism 501 so that the imaging mechanism 501 shoots the cell image of the specific area of the smear, and the image analyzing mechanism 503 is used for analyzing the cell image of the smear to obtain the corresponding analysis result, as shown in fig. 2B.
Referring to fig. 3, the unloading device 60 includes an unloading transfer mechanism 601, a driving mechanism 602, and a detecting mechanism 603. The unloading and conveying mechanism 601 is provided with a plurality of unloading and conveying positions 6011 for conveying the slide baskets, the detection mechanism 603 is used for detecting the state information of the corresponding unloading and conveying position 6011 and generating corresponding feedback signals, and the driving mechanism 602 is used for driving the unloading and conveying mechanism 601 so as to realize the unloading of the slide baskets conveyed on the unloading and conveying mechanism 601.
In some embodiments, the unloading unit 60 further includes a transfer mechanism 604 for transferring the slide basket, by which the slide basket can be transferred to a corresponding unloading transfer station 6011 of the unloading transfer mechanism 601, or from the corresponding unloading transfer station 6011 to a corresponding storage area or device.
Referring to fig. 4A-4B, the unloading and transferring mechanism 601 includes a transferring and placing end and a transferring and unloading end, a plurality of unloading and transferring positions 6011 are formed between the transferring and placing end and the transferring and unloading end for transferring the slide basket to be unloaded, and the transfer direction of the slide basket on the unloading and transferring mechanism 601 is from the transferring and placing end to the transferring and unloading end, wherein the unloading and transferring mechanism 601 may be a conveyor belt or a roller, which is not limited herein.
The detection mechanism 603 includes a first detector 6031 and a second detector 6032 connected to the control device 40, the first detector 6031 is disposed corresponding to the transfer-placing end, and the second detector 6032 is disposed corresponding to the transfer-unloading end.
The unloading device 60 further comprises a limiting mechanism, which is arranged corresponding to the conveying and unloading end and is used for giving a corresponding limit to the slide basket to be unloaded after the corresponding slide basket to be unloaded is conveyed to the corresponding position to be unloaded by the unloading and conveying mechanism 601 in the conveying direction and preventing the slide basket to be unloaded from being separated from the position to be unloaded in the conveying direction, so that the detecting mechanism 603 can know whether the unloading and conveying of the unloading and conveying mechanism 601 is 6011 full load.
In some embodiments, the sheet reading device 30 or the unloading device 60 further includes a control device, which may be the same control device as the control device 40 of the sample analysis system 100 or a control device independent from the sample analysis system 100, but in this embodiment, the control device shared by the sheet reading device 30, the unloading device 60 and the sample analysis system 100 is taken as an example, and the control device can be shared by the sheet reading device 30, the unloading device 60 and the sample analysis system 100.
Specifically, the control device 40 includes at least a processor 401, a memory 402, and a communication interface. The communication interface, memory 402, and processor 401 communicate via a bus connection.
The Memory 402 may be a volatile Memory (volatile Memory), such as a Random Access Memory (RAM); or a non-volatile Memory (non-volatile Memory), such as a Read Only Memory (ROM), a flash Memory (flash Memory), a Hard Disk (Hard Disk Drive, HDD) or a Solid-State Drive (SSD); or a combination of the above kinds of memories. The memory 402 is used to store computer programs that may provide instructions and data to the processor 401.
The Processor 401 may be a Central Processing Unit (CPU), and may also be other general purpose processors, Digital Signal Processors (DSP), Application Specific Integrated Circuits (ASIC), Field Programmable Gate Arrays (FPGA) or other Programmable logic devices, discrete Gate or transistor logic devices, discrete hardware components, and so forth. Wherein a general purpose processor may be a microprocessor or the processor may be any conventional processor or the like.
The processor 401 is configured to call a computer program stored in the memory 402, so as to execute the following method:
receiving an unloading instruction;
controlling the detecting mechanism 603 to detect status information corresponding to the unloading transport position 6011 according to the unloading instruction and generate a corresponding feedback signal, where the status information is used to indicate whether the unloading transport position 6011 is empty;
and controlling the driving mechanism 602 to drive the unloading transmission mechanism 601 to execute a corresponding unloading task according to the feedback signal.
In some embodiments, when controlling the detecting mechanism 603 according to the unloading instruction to detect the status information corresponding to the unloading transport position 6011 and generate a corresponding feedback signal, the processor 401 includes:
and controlling the driving mechanism 602 to drive the unloading and conveying mechanism 601 to execute at least one unloading task in the conveying direction according to the unloading instruction, and controlling the first detector 6031 and the second detector 6032 to detect whether the corresponding unloading and conveying position 6011 is empty or not and generate corresponding feedback signals, wherein each unloading task is used for conveying at least one slide basket by a preset distance in the conveying direction.
In some embodiments, the feedback signal comprises a first feedback signal generated by the detection mechanism 603 when the first detector detects 6031 that the corresponding unload transfer position 6011 is empty and the second detector detects 6032 that the corresponding unload transfer position 6011 is empty; when the processor 401 controls the driving mechanism 602 to drive the unloading conveying mechanism 601 to execute the corresponding unloading task according to the feedback signal, the processor includes:
and controlling the driving mechanism 603 to drive the unloading conveying mechanism 601 to execute a plurality of unloading tasks in the conveying direction according to the first feedback signal.
In some embodiments, the feedback signal includes a first feedback signal generated by the detection mechanism 603 when the first detector 6031 detects that the corresponding unload transfer station 6011 is empty and the second detector 6032 detects that the corresponding unload transfer station 6011 is empty; the unloading device 60 further comprises a transfer mechanism 604 for transferring the slide basket, and the processor 401, when controlling the driving mechanism 602 to drive the unloading transmission mechanism 601 to execute the corresponding unloading task according to the feedback signal, comprises:
and controlling the transfer mechanism 604 to transfer the corresponding slide basket to the conveying and placing end of the unloading and conveying mechanism 601 according to the first feedback signal, and controlling the driving mechanism 602 to drive the unloading and conveying mechanism 601 to execute a plurality of unloading tasks in the conveying direction.
In some embodiments, the feedback signal comprises a second feedback signal when one of the first and second detectors 6031, 6032 detects that the corresponding unload transport position 6011 is not empty and the other detects that the corresponding unload transport position 6011 is empty; when the processor 401 controls the driving mechanism 602 to drive the unloading conveying mechanism 601 to execute the corresponding unloading task according to the feedback signal, the processor includes:
and controlling the driving mechanism 602 to drive the unloading conveying mechanism 601 to execute an unloading task in the conveying direction according to the second feedback signal.
In some embodiments, the feedback signal comprises a second feedback signal generated by the detection mechanism 603 when one of the first and second detectors 6031, 6032 detects that the corresponding unload transport position 6011 is not empty and the other detects that the corresponding unload transport position 6011 is empty; the unloading device 60 further comprises a transfer mechanism 604 for transferring the slide basket, and the processor 401, when controlling the driving mechanism 602 to drive the unloading transmission mechanism 601 to execute the corresponding unloading task according to the feedback signal, comprises:
and controlling the transfer mechanism 604 to transfer the corresponding slide basket to the conveying and placing end of the unloading and conveying mechanism 601 according to the second feedback signal, and controlling the driving mechanism 602 to drive the unloading and conveying mechanism 601 to execute an unloading task in the conveying direction.
In some embodiments, the feedback signal comprises a third feedback signal generated by the detection mechanism 603 when the first detector 6031 and the second detector 6032 detect that the corresponding unloading transfer station 6011 is not empty; when the processor 401 controls the driving mechanism 602 to drive the unloading conveying mechanism 601 to execute the corresponding unloading task according to the feedback signal, the processor includes:
and controlling the driving mechanism 602 to stop driving the unloading conveying mechanism 601 according to the third feedback signal, and generating full information of the unloading conveying position 6011.
In some embodiments, the processor 401 is further configured to perform:
when the unload transfer bit is full, controlling the second detector 6032 to detect whether the corresponding unload transfer bit is empty;
when the second detector 6032 detects that the corresponding unloading transfer position is empty, the driving mechanism 602 is controlled to drive the unloading transfer mechanism 601 to perform a plurality of unloading tasks in the transfer direction.
In some embodiments, the processor 401 is further configured to perform:
controlling the first detector 6031 to detect whether the corresponding unload transfer bit is empty;
when the first detector 6031 detects that the unloading transfer position corresponding thereto is empty, the unloading device 60 failure information is generated.
In the above embodiments, the descriptions of the embodiments have respective emphasis, and for parts that are not described in detail in a certain embodiment, reference may be made to the following detailed description of the unloading method, and details are not described here again.
The unloading method provided by the embodiment of the present application will be described in detail below with reference to the working principle of the sample analysis system.
Referring to fig. 5, the smear loading and unloading method is applied to the above sample analysis system, the slide reading apparatus or the unloading device, and includes steps S101 to S103.
And S101, receiving an unloading instruction.
The working state of the sample analysis system, the slide reading equipment or the unloading device is monitored through the monitoring device, when the slide basket needs to be unloaded, the monitoring device produces a corresponding unloading instruction and sends the unloading instruction to the control device, and the control device executes operation corresponding to the unloading instruction when receiving the unloading instruction.
It will be appreciated that in some embodiments, the unload instruction may be issued by an operator to the sample analysis system via an input device. The input device may be a mouse, a keyboard, a touch display screen or a button, and the like, which is not limited herein.
In some embodiments, the unload instruction may also be issued by a remote control device communicatively coupled to the sample analysis system, the slide reading apparatus, or the unload device.
S102, controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty or not.
And after receiving the unloading instruction, the control device controls the detection mechanism to detect whether the corresponding transmission position is vacant according to the unloading instruction, and generates a corresponding feedback signal according to a detection result.
In some embodiments, the controlling the detection mechanism to detect the status information corresponding to the unload transfer bit and generate the corresponding feedback signal according to the unload instruction includes:
and controlling the driving mechanism to drive the unloading conveying mechanism to execute at least one unloading task in the conveying direction according to the unloading instruction, controlling the first detector and the second detector to detect whether the corresponding unloading conveying positions are empty or not, and generating corresponding feedback signals, wherein each unloading task is used for conveying at least one slide basket for a preset distance in the conveying direction.
Illustratively, the detection mechanism includes a first detector and a second detector; the unloading conveying mechanism comprises a conveying placing end and a conveying unloading end, a plurality of unloading conveying positions are formed between the conveying placing end and the conveying unloading end, and the conveying direction of the slide basket on the unloading conveying mechanism is from the conveying placing end to the conveying unloading end; the first detector is arranged corresponding to the transmission placing end, and the second detector is arranged corresponding to the transmission unloading end.
When an unloading instruction is received, the driving mechanism is controlled to drive the unloading transmission mechanism to execute at least one unloading task in the transmission direction, so that the phenomenon that the detection machine falsely reports full load due to the fact that the unloading transmission positions corresponding to the first detector and the second detector have the slide basket is effectively avoided being controlled by unloading of the middle part of the unloading transmission mechanism.
And after the driving mechanism drives the unloading transmission mechanism to execute at least one unloading task in the transmission direction, acquiring information whether a first detector and a second detector of the detection mechanism respectively detect the unloading transmission position, and generating a corresponding feedback signal according to the detection result. The feedback signals comprise a first feedback signal, a second feedback signal and a third feedback signal, wherein the first feedback signal indicates that the unloading transmission position detected by the first detector is empty, and the unloading transmission position detected by the second detector is empty. A second feedback signal is indicative of one of the first detector and the second detector detecting that the corresponding offload transfer site is not empty and the other detecting that the corresponding offload transfer site is empty. And the third feedback signal represents that the unloading transmission positions detected by the first detector and the second detector are both non-empty.
The vacant representation represents that the slide basket is not placed at the current unloading conveying position, and on the contrary, the non-vacant representation represents that the slide basket is placed at the current unloading conveying position.
S103, controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
And the control device controls the driving mechanism to drive the unloading transmission mechanism to execute the unloading task corresponding to the feedback signal according to the received feedback signal.
In some embodiments, the controlling the driving mechanism to drive the unloading conveying mechanism to execute the corresponding unloading task according to the feedback signal includes:
and when the received feedback signal is a first feedback signal, controlling the driving mechanism to drive the unloading transmission mechanism to execute multiple unloading tasks in the transmission direction according to the first feedback signal.
Illustratively, when a first feedback signal indicating that the first detector detects that the corresponding unloading conveying position is empty and the second detector detects that the corresponding unloading conveying position is empty is received, the first feedback signal indicates that the unloading conveying position is still empty and is not fully utilized, the control device controls the driving mechanism to drive the unloading conveying mechanism to execute a plurality of unloading tasks in the conveying direction according to the first feedback signal, and each unloading task is used for conveying at least one slide basket in the conveying direction by a preset distance.
As shown in fig. 6A, after the slide baskets placed at the unloading transfer positions at the opposite ends of the unloading transfer mechanism are unloaded or the slide baskets on the unloading transfer mechanism are completely unloaded, the first detector disposed at the transfer placing end and the second detector disposed at the transfer unloading end generate the unloading transfer position empty signal correspondingly.
At this time, if the slide basket M exists on the middle unloading transfer position of the unloading transfer mechanism, the first detector and the second detector cannot detect the related information, and in order to fully utilize the unloading transfer position, the corresponding state information of a plurality of transfer positions needs to be known, so that the control device controls the driving mechanism to drive the unloading transfer mechanism to execute a plurality of unloading tasks in the transfer direction to travel a plurality of preset distances.
If a preset distance causes the slide basket to travel one unload transfer station in the transfer direction, the unload transfer mechanism shown in figure 6A travels 5 preset distances in the transfer direction. If the number of the unloading transmission positions is N, after the unloading transmission mechanism executes N times of unloading tasks in the transmission direction, whether the corresponding unloading transmission positions have the state information of the slide baskets to be unloaded or not can be judged through detection signals output by the first detector and the second detector, so that the slide baskets to be unloaded are placed to the corresponding unloading transmission positions according to the state information of the unloading transmission positions, the unloading transmission positions of the unloading transmission mechanism can be fully utilized, the no-load state of partial unloading transmission positions is avoided, and meanwhile, the slide baskets on the unloading transmission positions corresponding to the second detector can be unloaded periodically or manually through a manipulator.
In some embodiments, the unloading device further comprises a transfer mechanism for transferring the slide basket, and the controlling the driving mechanism to drive the unloading transmission mechanism to execute the corresponding unloading task according to the feedback signal comprises:
and when the received feedback signal is a first feedback signal, controlling the transfer mechanism to transfer the corresponding slide basket to the transmission placing end of the unloading transmission mechanism according to the first feedback signal, and controlling the driving mechanism to drive the unloading transmission mechanism to execute a plurality of unloading tasks in the transmission direction.
As shown in fig. 6B, if there is a slide basket M on the middle unloading transfer position of the unloading transfer mechanism, the first detector and the second detector cannot detect the related information, and in order to fully utilize the unloading transfer position, the corresponding status information of the plurality of transfer positions needs to be known, so the control device controls the driving mechanism to drive the unloading transfer mechanism to perform a plurality of unloading tasks in the transfer direction to travel a plurality of preset distances, and periodically or manually unload the slide basket on the unloading transfer position corresponding to the second detector by the robot.
Meanwhile, the transfer mechanism can be controlled to place the slide basket to be unloaded to the unloading conveying position corresponding to the detected no-load according to the state information of the unloading conveying position detected by the first detector, so that the unloading conveying position of the unloading conveying mechanism can be fully utilized, and the no-load state of part of the unloading conveying positions is avoided.
In some embodiments, the controlling the driving mechanism to drive the unloading conveying mechanism to execute the corresponding unloading task according to the feedback signal includes:
and when the received feedback signal is a second feedback signal, controlling the driving mechanism to drive the unloading transmission mechanism to execute an unloading task in the transmission direction according to the second feedback signal.
Referring to fig. 6C, when a second feedback signal indicating that one of the first and second detectors detects that the corresponding unloading transfer position is not empty and the other one of the first and second detectors detects that the corresponding unloading transfer position is empty indicates that the current unloading transfer position may be in a normal loading or unloading state, the driving mechanism is controlled to drive the unloading transfer mechanism to move a predetermined distance in the transfer direction, and the robot arm periodically or manually unloads the slide basket on the unloading transfer position corresponding to the second detector.
In some embodiments, the unloading device further comprises a transfer mechanism for transferring the slide basket, and the controlling the driving mechanism to drive the unloading transmission mechanism to execute the corresponding unloading task according to the feedback signal comprises:
and when the received feedback signal is a second feedback signal, controlling the transfer mechanism to transfer the corresponding slide basket to the transmission placing end of the unloading transmission mechanism according to the second feedback signal, and controlling the driving mechanism to drive the unloading transmission mechanism to execute an unloading task in the transmission direction.
Referring to fig. 6C, when a second feedback signal indicating that one of the first detector and the second detector detects that the corresponding unloading transfer position is not empty and the other one of the first detector and the second detector detects that the corresponding unloading transfer position is empty indicates that the current unloading transfer position is in a normal loading or unloading state, the driving mechanism is controlled to drive the unloading transfer mechanism to perform an unloading task in the transfer direction, and the transfer mechanism is controlled to transfer the corresponding slide basket to the transfer end of the unloading transfer mechanism, so as to achieve the ordered unloading of the slide baskets.
In some embodiments, the controlling the driving mechanism to drive the unloading conveying mechanism to execute the corresponding unloading task according to the feedback signal includes:
and when the received feedback signal is a third feedback signal, controlling the driving mechanism to stop driving the unloading conveying mechanism to act according to the third feedback signal, and generating the unloading conveying position full load information.
Referring to fig. 6D, a third feedback signal indicates that the unloading transport positions detected by the first detector and the second detector are both non-empty, and then the driving mechanism is controlled to stop driving the unloading transport mechanism according to the third feedback signal, so as to generate loading information of the unloading transport positions.
In some embodiments, the method further comprises:
when the unloading transmission positions are full, controlling the second detector to detect whether the corresponding unloading transmission positions are empty;
and when the second detector detects that the corresponding unloading transmission position is empty, controlling the driving mechanism to drive the unloading transmission mechanism to execute multiple unloading tasks in the transmission direction.
Illustratively, when the unloading transfer positions are full, controlling a second detector to periodically detect whether the corresponding unloading transfer positions are empty, thereby judging whether the slide baskets on the unloading transfer positions corresponding to the second detector are unloaded; when the second detector detects that the corresponding unloading transmission position is empty, the slide basket on the corresponding unloading transmission position is indicated to be unloaded, and the driving mechanism is controlled to drive the unloading transmission mechanism to execute a plurality of unloading tasks in the transmission direction, so that the slide basket is unloaded orderly.
In some embodiments, after controlling the driving mechanism to drive the unloading conveying mechanism to perform a plurality of unloading tasks in the conveying direction, the method further comprises:
controlling the first detector to detect whether the corresponding unloading transmission position is empty;
and when the first detector detects that the corresponding unloading transmission position is empty, generating the unloading device fault information.
Illustratively, when the driving mechanism drives the unloading conveying mechanism to execute a plurality of unloading tasks in the conveying direction, which indicates that the current unloading conveying mechanism is in a normal working mode, the first detector is controlled to detect whether the corresponding unloading conveying position is empty; and when the first detector detects that the corresponding unloading transmission position is empty, the first detector indicates that a fault possibly exists in the current unloading device, so that the corresponding unloading transmission position cannot receive the slide basket to be transmitted, and fault information of the unloading device is generated.
It is to be understood that the terminology used in the description of the present application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. As used in the specification of the present application and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
It should also be understood that the term "and/or" as used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items. It should be noted that, in this document, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or system that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or system. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other like elements in a process, method, article, or system that comprises the element.
The above-mentioned serial numbers of the embodiments of the present application are merely for description and do not represent the merits of the embodiments. While the invention has been described with reference to specific embodiments, the scope of the invention is not limited thereto, and various equivalent modifications or substitutions can be easily made by those skilled in the art within the technical scope of the invention. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.
Claims (14)
1. A sample analysis system, comprising:
the blood analyzer is used for carrying out conventional blood detection on a sample to be detected;
the smear preparation device is used for preparing the sample to be detected into a smear and placing the smear into a slide basket;
the slide reading device comprises an unloading device for unloading the slide basket and a slide reading device for acquiring cell images in the to-be-detected sample smeared on the coating and analyzing the cell images; the unloading device comprises an unloading conveying mechanism, a driving mechanism and a detection mechanism, wherein the unloading conveying mechanism is provided with a plurality of unloading conveying positions for conveying the slide baskets, the detection mechanism is used for detecting state information corresponding to the unloading conveying positions and generating corresponding feedback signals, and the driving mechanism is used for driving the unloading conveying mechanism;
a memory for storing a computer program; and
a processor for invoking a computer program in the memory to perform:
receiving an unloading instruction;
controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty;
and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
2. The sample analysis system of claim 1, wherein the detection mechanism comprises a first detector and a second detector;
the unloading conveying mechanism comprises a conveying placing end and a conveying unloading end, a plurality of unloading conveying positions are formed between the conveying placing end and the conveying unloading end, and the conveying direction of the slide basket on the unloading conveying mechanism is from the conveying placing end to the conveying unloading end;
the first detector is arranged corresponding to the transmission placing end, and the second detector is arranged corresponding to the transmission unloading end.
3. The sample analysis system of claim 2, wherein the processor, in controlling the detection mechanism to detect status information corresponding to the unload transport bits and generate corresponding feedback signals in accordance with the unload instructions, comprises:
and controlling the driving mechanism to drive the unloading conveying mechanism to execute at least one unloading task in the conveying direction according to the unloading instruction, controlling the first detector and the second detector to detect whether the corresponding unloading conveying positions are empty or not, and generating corresponding feedback signals, wherein each unloading task is used for conveying at least one slide basket for a preset distance in the conveying direction.
4. The sample analysis system of claim 3, wherein the feedback signal comprises a first feedback signal generated by the detection mechanism when the first detector detects that the corresponding unload transport position is empty and the second detector detects that the corresponding unload transport position is empty; when the processor controls the driving mechanism to drive the unloading transmission mechanism to execute the corresponding unloading task according to the feedback signal, the method comprises the following steps:
and controlling the driving mechanism to drive the unloading conveying mechanism to execute multiple unloading tasks in the conveying direction according to the first feedback signal.
5. The sample analysis system of claim 3, wherein the feedback signal comprises a first feedback signal generated by the detection mechanism when the first detector detects that the corresponding unload transport position is empty and the second detector detects that the corresponding unload transport position is empty; the unloading device also comprises a transfer mechanism for transferring the slide basket, and the processor, when controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal, comprises:
and controlling the transfer mechanism to transfer the corresponding slide basket to a transmission placing end of the unloading and conveying mechanism according to the first feedback signal, and controlling the driving mechanism to drive the unloading and conveying mechanism to execute multiple unloading tasks in the transmission direction.
6. The sample analysis system of claim 3, wherein the feedback signal comprises a second feedback signal when one of the first and second detectors detects that the corresponding unload transport position is not empty and the other detects that the corresponding unload transport position is empty; when the processor controls the driving mechanism to drive the unloading transmission mechanism to execute the corresponding unloading task according to the feedback signal, the method comprises the following steps:
and controlling the driving mechanism to drive the unloading conveying mechanism to execute an unloading task in the conveying direction according to the second feedback signal.
7. The sample analysis system of claim 3, wherein the feedback signal comprises a second feedback signal generated by the detection mechanism when one of the first and second detectors detects that the corresponding unload transport position is not empty and the other detects that the corresponding unload transport position is empty; the unloading device also comprises a transfer mechanism for transferring the slide basket, and the processor, when controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal, comprises:
and controlling the transfer mechanism to transfer the corresponding slide basket to the transmission placing end of the unloading transmission mechanism according to the second feedback signal, and controlling the driving mechanism to drive the unloading transmission mechanism to execute an unloading task in the transmission direction.
8. The sample analysis system of claim 3, wherein the feedback signal comprises a third feedback signal generated by the detection mechanism when the first detector and the second detector detect that the corresponding unload transport position is not empty; when the processor controls the driving mechanism to drive the unloading transmission mechanism to execute the corresponding unloading task according to the feedback signal, the method comprises the following steps:
and controlling the driving mechanism to stop driving the unloading conveying mechanism to act according to the third feedback signal, and generating the unloading conveying position full load information.
9. The sample analysis system of claim 8, wherein the processor is further configured to perform:
when the unloading transmission positions are full, controlling the second detector to detect whether the corresponding unloading transmission positions are empty;
and when the second detector detects that the corresponding unloading transmission position is empty, controlling the driving mechanism to drive the unloading transmission mechanism to execute multiple unloading tasks in the transmission direction.
10. The sample analysis system of claim 9, wherein the processor is further configured to perform:
controlling the first detector to detect whether the corresponding unloading transmission position is empty;
and when the first detector detects that the corresponding unloading transmission position is empty, generating the unloading device fault information.
11. The specimen analysis system of claim 9, wherein the slide interpreting apparatus further comprises: the smear analysis system comprises an imaging mechanism, a smear moving mechanism and an image analysis mechanism, wherein the imaging mechanism is used for shooting cells in a sample to be detected smeared on a smear; the smear moving mechanism is used for moving the smear relative to the imaging mechanism so that the imaging mechanism shoots a cell image of a specific area of the smear; the image analysis mechanism is used for analyzing the cell image of the smear.
12. The slide reading equipment is characterized by comprising an unloading device for unloading a slide basket and a slide reading device for acquiring a cell image in a sample to be tested smeared on a coating and analyzing the cell image;
the unloading device comprises an unloading conveying mechanism, a driving mechanism and a detection mechanism, wherein the unloading conveying mechanism is provided with a plurality of unloading conveying positions for conveying the slide baskets, the detection mechanism is used for detecting state information corresponding to the unloading conveying positions and generating corresponding feedback signals, and the driving mechanism is used for driving the unloading conveying mechanism;
a memory for storing a computer program; and
a processor for invoking a computer program in the memory to perform:
receiving an unloading instruction;
controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty;
and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
13. The unloading device is characterized by comprising an unloading conveying mechanism, a driving mechanism and a detection mechanism, wherein the unloading conveying mechanism is provided with a plurality of unloading conveying positions for conveying slide baskets, the detection mechanism is used for detecting state information corresponding to the unloading conveying positions and generating corresponding feedback signals, and the driving mechanism is used for driving the unloading conveying mechanism;
a memory for storing a computer program; and
a processor for invoking a computer program in the memory to perform:
receiving an unloading instruction;
controlling the detection mechanism to detect state information corresponding to the unloading transmission position according to the unloading instruction and generating a corresponding feedback signal, wherein the state information is used for representing whether the unloading transmission position is empty;
and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
14. The unloading method is applied to an unloading device and is characterized in that the unloading device comprises an unloading and conveying mechanism, a driving mechanism and a detection mechanism, wherein the unloading and conveying mechanism is provided with a plurality of unloading and conveying positions for conveying slide baskets, the detection mechanism is used for detecting state information corresponding to the unloading and conveying positions and generating corresponding feedback signals, and the driving mechanism is used for driving the unloading and conveying mechanism;
the method comprises the following steps:
receiving an unloading instruction;
controlling the detection mechanism to detect state information corresponding to the unloading transmission position and generate a corresponding feedback signal according to the unloading instruction, wherein the state information is used for representing whether the unloading transmission position is empty;
and controlling the driving mechanism to drive the unloading transmission mechanism to execute a corresponding unloading task according to the feedback signal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011543134.XA CN114646757A (en) | 2020-12-21 | 2020-12-21 | Sample analysis system, film reading equipment, unloading device and unloading method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011543134.XA CN114646757A (en) | 2020-12-21 | 2020-12-21 | Sample analysis system, film reading equipment, unloading device and unloading method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114646757A true CN114646757A (en) | 2022-06-21 |
Family
ID=81992117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011543134.XA Pending CN114646757A (en) | 2020-12-21 | 2020-12-21 | Sample analysis system, film reading equipment, unloading device and unloading method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114646757A (en) |
-
2020
- 2020-12-21 CN CN202011543134.XA patent/CN114646757A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5557933B2 (en) | Sample processing system | |
| CN104520718B (en) | The transport method of sample test automation system and a corpse or other object for laboratory examination and chemical testing | |
| JP7392097B2 (en) | Analysis method | |
| CN101118245B (en) | Automatic analyzer | |
| JP6220781B2 (en) | Centrifuge, pretreatment system equipped with centrifuge, and control method of the system | |
| CN110325865A (en) | Automatic analysing apparatus | |
| JP6499872B2 (en) | Specimen transfer device and specimen transport system | |
| JP6777728B2 (en) | Specimen transfer system and sample transfer method | |
| CN111392402A (en) | Automatic grabbing method, device, equipment and storage medium | |
| JP6426569B2 (en) | Sample inspection system | |
| US20200081419A1 (en) | Server and controlling method thereof | |
| CN114646757A (en) | Sample analysis system, film reading equipment, unloading device and unloading method | |
| CN111279198B (en) | Automatic analyzer | |
| JP6078355B2 (en) | Automatic analyzer and sample rack transport method | |
| JP6047399B2 (en) | Sample transport system in automatic analyzer | |
| JP6143549B2 (en) | Sample processing system | |
| US20220050121A1 (en) | System and method for device specific quality control | |
| JP3710534B2 (en) | Process control method | |
| CN105717893B (en) | Material inspects process optimization control system and control method by random samples | |
| CN216285342U (en) | Sample analysis system and sample scheduling system | |
| JP2009092448A (en) | Fluorescent x-ray analysis system, and program used for its system | |
| US20230184795A1 (en) | Automatic analyzer | |
| JP4880932B2 (en) | Inspection device | |
| JP4571686B2 (en) | Analysis system | |
| JP6221109B2 (en) | Sample analysis system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |