CN114606116A - Culture system for herpes zoster vaccine - Google Patents
Culture system for herpes zoster vaccine Download PDFInfo
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- CN114606116A CN114606116A CN202210303950.6A CN202210303950A CN114606116A CN 114606116 A CN114606116 A CN 114606116A CN 202210303950 A CN202210303950 A CN 202210303950A CN 114606116 A CN114606116 A CN 114606116A
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- 229960005486 vaccine Drugs 0.000 title claims abstract description 27
- 208000007514 Herpes zoster Diseases 0.000 title claims abstract description 22
- 230000007246 mechanism Effects 0.000 claims abstract description 59
- 238000010438 heat treatment Methods 0.000 claims abstract description 10
- 238000002474 experimental method Methods 0.000 claims abstract description 6
- 238000003466 welding Methods 0.000 claims description 27
- 238000005192 partition Methods 0.000 claims description 23
- 230000000149 penetrating effect Effects 0.000 claims description 2
- 238000007599 discharging Methods 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 2
- 230000000694 effects Effects 0.000 description 4
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010046865 Vaccinia virus infection Diseases 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 238000002255 vaccination Methods 0.000 description 1
- 208000007089 vaccinia Diseases 0.000 description 1
- 238000010792 warming Methods 0.000 description 1
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
- C12M41/20—Heat exchange systems, e.g. heat jackets or outer envelopes the heat transfer medium being a gas
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/26—Conditioning fluids entering or exiting the reaction vessel
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
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Abstract
The invention discloses a culture system for herpes zoster vaccines, which relates to the technical field of vaccine culture devices, and particularly relates to a culture system for herpes zoster vaccines, which comprises an incubator, wherein a baffle is welded on the front end surface of the incubator, the front end surface of the incubator is rotatably connected with a chamber door on the side surface of the baffle, an observation window is embedded in the side surface of the chamber door, an experiment support is arranged in an inner cavity of the incubator, a temperature monitor and a humidity monitor are arranged at the upper end of the inner cavity of the incubator in a threaded manner, a driving mechanism is arranged on the inner side surface of the baffle, and a locking mechanism is arranged on the outer side surface of the baffle, and the culture system has the beneficial effects that: through adjustment mechanism, actuating mechanism and the adjustment mechanism cooperation that sets up, the hot-blast volume of regulation that can be convenient to can adjust the volume of heating, and then reach the temperature control to incubator inside, rotate the inside of discharging the incubator with hot-blast and moisture is even through going out the tuber pipe, make the temperature and the humidity evenly distributed of incubator inner chamber, thereby guarantee the stable cultivation of bacterin.
Description
Technical Field
The invention relates to the technical field of vaccine culture devices, in particular to a culture system for herpes zoster vaccines.
Background
The vaccine is a biological product which is prepared from various pathogenic microorganisms and is used for vaccination, and the vaccine is the most economical and effective means for preventing and controlling infectious diseases, and plays an important role in protecting human health from the earliest vaccinating vaccinia to the present diversified vaccines. Since different vaccines require different temperatures, humidities, and the like during culture, a dedicated culture apparatus is required. Because the required temperature and humidity of different time of bacterin cultivation also are different, in order to discover the better cultivation temperature and humidity of bacterin, so need make the bacterin be under different temperature and humidity, but current bacterin culture apparatus has certain defect when using, and inside temperature and humidity can't accurate control to current bacterin culture apparatus, and temperature and humidity are too high and too low can lead to the cultivation failure, have so influenced the result of experiment greatly. And current culture apparatus is when heating up and the humidification to bacterin, and most direct heats and humidifies in to the incubator through air outlet and humidification pipe, causes the temperature and the humidity inhomogeneous in the incubator like this easily, and can't be quick with the temperature and the humidity control in the incubator to required cultivation environment to influence the cultivation of bacterin. To this end, we propose a culture system for herpes zoster vaccines to solve the above drawbacks.
Disclosure of Invention
The present invention aims to provide a culture system for herpes zoster vaccine to solve the problems in the background art.
In order to achieve the purpose, the invention provides the following technical scheme: a culture system for herpes zoster vaccines comprises an incubator, wherein a baffle is welded on the front end face of the incubator, the front end face of the incubator is rotatably connected with a chamber door on the side face of the baffle, an observation window is embedded in the side face of the chamber door, an experiment support is installed in an inner chamber of the incubator, a temperature monitor and a humidity monitor are installed on the upper end thread of the inner chamber of the incubator, a driving mechanism is installed on the inner side face of the baffle, a locking mechanism is arranged on the outer side face of the baffle, a fixing plate is welded on the inner chamber of the incubator, a humidifier is installed on the side face of the fixing plate, a humidifying pipe is connected to the side face of the humidifier through a pipe joint, a heating device is connected to one side, away from the humidifier, of the fixing plate through a bolt, a fan is installed on the inner side of the incubator, a partition plate is welded in the inner chamber of the incubator, and a circular groove is formed in the side face of the partition plate, the fan-shaped air conditioner is characterized in that four fan-shaped air outlets are formed in the side face of the circular groove in a circumferential array, one end of the humidifying pipe penetrates through the partition plate and extends out of the fan-shaped air outlets, an annular limiting groove is formed in the cylindrical surface of the circular groove, a fan-shaped groove is formed in the side face of the annular limiting groove, an adjusting mechanism is arranged in the circular groove, a rotating mechanism is installed on the side face of the partition plate, a fixed column is welded on the side face of the partition plate, a fixed gear is welded at one end of the fixed column, and a power mechanism is installed on the side face of the partition plate on one side of the rotating mechanism.
Preferably, the driving mechanism includes: the side welding of round bar has first helical gear, the other end of round bar passes baffle and round plate welding, the side welding of round plate has the gag lever post, the side meshing of first helical gear has the second helical gear, the side of second helical gear has drive gear through round pin hub connection.
Preferably, the driving gear is arranged in the partition plate and is rotatably connected with the partition plate through a pin shaft.
Preferably, the locking mechanism includes: location pick, rectangular channel, locking spring, fixed pick, direction round hole, sector plate, activity post, guide way and adjust knob, the side of circular slab is provided with the location pick, the rectangular channel has been seted up to the side of location pick, the side welding of location pick has the locking spring, the side joint of location pick has fixed pick, the symmetrical welding has the sector plate about the side of fixed pick, sector plate and baffle welding, the direction round hole has been seted up to the side of fixed pick, the side welding of location pick has the activity post, the one end of activity post is run through and is seted up the guide way, the one end of activity post is passed the direction round hole and is welded with adjust knob.
Preferably, the side that location tooth piece and fixed tooth piece are a circular block becomes the circumference array and has seted up the skewed tooth, the one end of gag lever post passes rectangular channel and guide way in proper order, and gag lever post and rectangular channel, guide way sliding connection.
Preferably, the adjusting mechanism comprises: the fan-shaped tooth adjusting mechanism comprises adjusting circular plates, fan-shaped through grooves, annular positioning plates and fan-shaped teeth, wherein the adjusting circular plates are connected in the circular grooves in a rotating mode, the four fan-shaped through grooves are formed in the side faces of the adjusting circular plates in a circumferential array, the annular positioning plates are welded on the cylindrical surfaces of the adjusting circular plates, and the fan-shaped teeth are welded on the side faces of the annular positioning plates.
Preferably, the annular positioning plate is rotatably connected with the annular limiting groove, the sector-shaped teeth are rotatably connected with the sector-shaped groove, and the sector-shaped teeth are meshed with the driving gear.
Preferably, the rotating mechanism includes: annular limiting plate, drum, annular bellying, fixed plectane, through-hole, annular constant head tank, first ring gear, play tuber pipe, exhaust vent, spacing ring and second ring gear, the side welding of baffle has annular limiting plate, the inboard rotation of annular limiting plate is connected with the drum, the one end of drum is provided with annular bellying, the other end welding of drum has fixed plectane, four through-holes have been seted up to the side of fixed plectane one-tenth circumference array, annular constant head tank has been seted up to the inboard of through-hole, the outside welding of drum has first ring gear, the through-hole internal rotation is connected with out the tuber pipe, the exhaust vent has been seted up to the one end one-tenth circumference array of play tuber pipe, the outside welding of play tuber pipe has the spacing ring, the other end welding of play tuber pipe has second ring gear.
Preferably, the annular boss is rotatably connected with the annular limiting plate, the cross section of the annular limiting plate is arranged in an L shape, the limiting ring is rotatably connected with the annular positioning groove, and the second gear ring is meshed with the fixed gear.
Preferably, the power mechanism comprises: the motor comprises a concave seat, a motor shaft and a power gear, wherein the concave seat is welded on the side face of the partition plate, the motor shaft is rotatably connected to the side face of the concave seat, the power gear is welded at one end of the motor shaft, and the power gear is meshed with a first gear ring.
Compared with the prior art, the invention has the beneficial effects that: the invention has reasonable structure and strong functionality, and has the following advantages:
1. when the size of the fan-shaped air outlet in the incubator needs to be adjusted, the adjusting knob is pressed inwards firstly, the adjusting knob drives the positioning tooth block to move through the movable column, so that the positioning tooth block is separated from the fixed tooth block, at the moment, the adjusting knob is rotated again, the adjusting knob drives the movable column, the limiting rod and the circular plate to rotate, the circular plate drives the first bevel gear to rotate through the circular rod, the first bevel gear drives the second bevel gear to rotate, the second bevel gear drives the driving gear to rotate through the pin shaft, the driving gear drives the fan-shaped teeth in the adjusting mechanism to rotate, so that the adjusting circular plate rotates along the circular groove, the overlapped part of the fan-shaped through groove and the fan-shaped air outlet is gradually reduced, thereby reducing the hot air output, when the fan-shaped through groove and the fan-shaped air outlet are completely staggered and distributed, at the fan-shaped air outlet is completely sealed, and then heating is stopped, and the adjusting mechanism, the driving mechanism and the adjusting mechanism are matched, the output of hot air can be conveniently adjusted, so that the heating amount can be adjusted, and the temperature inside the incubator can be controlled;
2. carry out the humidification in the incubator through humidifier and the cooperation of humidification pipe that sets up, rotary mechanism and the cooperation of power unit through the setting, power gear through among the power unit drives first ring gear and drum and rotates, the drum drives fixed plectane and rotates, fixed plectane drives out the tuber pipe and rotates, it drives the second ring gear along fixed gear roll to go out the tuber pipe simultaneously, the second ring gear drives out the tuber pipe and rotates simultaneously, hot-blast and moisture all flow along the exhaust vent that goes out the tuber pipe, rotate the inside of discharging the incubator with hot-blast and moisture is even through going out the tuber pipe, make the temperature and the humidity evenly distributed of incubator inner chamber, thereby guarantee the stable cultivation of bacterin.
Drawings
FIG. 1 is a schematic structural diagram of a culture apparatus for herpes zoster vaccine according to the invention;
FIG. 2 is a schematic cross-sectional view of the culture apparatus for herpes zoster vaccine according to the present invention;
FIG. 3 is an enlarged view of the structure at A in FIG. 2;
FIG. 4 is an exploded view of the drive mechanism and locking mechanism configuration of the present invention;
FIG. 5 is a schematic view of the interior of the structure of the herpes zoster vaccine culturing device of the invention;
FIG. 6 is a schematic view of the structure of the partition and the adjusting mechanism of the present invention
FIG. 7 is a schematic view of the separator structure of the present invention;
FIG. 8 is a schematic view of an adjustment mechanism of the present invention;
FIG. 9 is a schematic view of a second bevel gear and drive gear arrangement of the present invention;
FIG. 10 is a schematic view of the partition, the rotating mechanism and the power mechanism according to the present invention;
fig. 11 is a schematic sectional view of the structure of the partition and the rotating mechanism of the present invention.
In the figure: 1. an incubator; 11. a baffle plate; 12. a box door; 13. an observation window; 14. an experiment bracket; 15. a temperature monitor; 16. a humidity monitor; 2. a round bar; 21. a first helical gear; 22. a circular plate; 23. a limiting rod; 24. a second helical gear; 25. a drive gear; 3. positioning a tooth block; 31. a rectangular groove; 32. a locking spring; 33. fixing the tooth block; 34. a guide circular hole; 35. a sector plate; 36. a movable post; 37. a guide groove; 38. adjusting a knob; 4. a fixing plate; 41. a humidifier; 42. a humidifying pipe; 43. a warming device; 44. a fan outlet; 5. a partition plate; 51. a circular groove; 52. a fan-shaped air outlet; 53. an annular limiting groove; 54. a sector groove; 55. adjusting the circular plate; 56. a fan-shaped through groove; 57. an annular positioning plate; 58. sector-shaped teeth; 6. an annular limiting plate; 61. a cylinder; 62. an annular boss; 63. fixing the circular plate; 64. a through hole; 65. an annular positioning groove; 66. a first gear ring; 67. fixing the column; 68. fixing a gear; 7. an air outlet pipe; 71. an air outlet; 72. a limiting ring; 73. a second gear ring; 8. a concave seat; 81. a motor shaft; 82. a power gear.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1 to 11, the present invention provides a technical solution: the utility model provides a culture system for herpes zoster bacterin, including incubator 1, the preceding terminal surface welding of incubator 1 has baffle 11, incubator 1's preceding terminal surface rotates in baffle 11's side and is connected with chamber door 12, the side embedding of chamber door 12 has observation window 13, experiment support 14 is installed to incubator 1's inner chamber, temperature monitor 15 and humidity monitor 16 are installed to the upper end screw thread of incubator 1 inner chamber, through the temperature monitor 15 and the humidity monitor 16 cooperation that set up, the temperature and the humidity of real-time 1 inner chamber of monitoring incubator.
Actuating mechanism is installed to baffle 11's medial surface, and actuating mechanism is including: round bar 2, first helical gear 21, circular slab 22, gag lever post 23, second helical gear 24 and drive gear 25, the side of baffle 11 is rotated and is connected with round bar 2, the one end welding of round bar 2 has first helical gear 21, the other end of round bar 2 passes baffle 11 and the welding of circular slab 22, the side welding of circular slab 22 has gag lever post 23, the side meshing of first helical gear 21 has second helical gear 24, there is drive gear 25 side of second helical gear 24 through the round pin hub connection, drive gear 25 sets up in baffle 5, and drive gear 25 rotates with baffle 5 through the round pin axle and is connected, rotate through gag lever post 23 and drive first helical gear 21 and rotate, first helical gear 21 drives second helical gear 24 and rotates, second helical gear 24 drives drive gear 25 through the round pin axle and rotates.
The lateral surface of baffle 11 is provided with locking mechanical system, and locking mechanical system is including: the positioning tooth block 3, the rectangular groove 31, the locking spring 32, the fixed tooth block 33, the round guide hole 34, the sector plate 35, the movable column 36, the guide groove 37 and the adjusting knob 38, the positioning tooth block 3 is arranged on the side surface of the circular plate 22, the rectangular groove 31 is formed in the side surface of the positioning tooth block 3, the locking spring 32 is welded on the side surface of the positioning tooth block 3, the fixed tooth block 33 is clamped on the side surface of the positioning tooth block 3, the sector plate 35 is welded on the side surface of the fixed tooth block 33 in an up-and-down symmetrical mode, the sector plate 35 is welded with the baffle 11, the round guide hole 34 is formed in the side surface of the fixed tooth block 33, the movable column 36 is welded on the side surface of the positioning tooth block 3, the guide groove 37 is formed in a penetrating mode at one end of the movable column 36, the side surfaces of the positioning tooth block 3 and the fixed tooth block 33 which are both circular blocks form a circumferential array and are provided with oblique teeth, one end of the limiting rod 23 sequentially penetrates through the rectangular groove 31 and the guide groove 37, and the limiting rod 23 and the rectangular groove 31, the limiting rod 23, The guide groove 37 is connected in a sliding manner, one end of the movable column 36 penetrates through the guide round hole 34 and is welded with the adjusting knob 38, the locking spring 32 is sleeved on the limiting rod 23, the locking spring 32 is arranged between the circular plate 22 and the positioning toothed block 3, and the locking spring 32 applies elasticity to the positioning toothed block 3.
Inner chamber welding of incubator 1 has fixed plate 4, the side-mounting of fixed plate 4 has humidifier 41, there is humidification pipe 42 side of humidifier 41 through the coupling joint, there is heating apparatus 43 one side that humidifier 41 was kept away from to fixed plate 4 through bolted connection, fan 44 is installed out to incubator 1's inboard, the inner chamber welding of incubator 1 has baffle 5, circular slot 51 has been seted up to baffle 5's side, four fan-shaped air outlets 52 have been seted up to circular slot 51's side one-tenth circumference array, humidification pipe 42's one end is passed baffle 5 and is extended out from fan-shaped air outlet 52 in, annular spacing groove 53 has been seted up to circular slot 51's the face of cylinder, fan-shaped groove 54 has been seted up to annular spacing groove 53's side, be provided with adjustment mechanism in the circular slot 51, adjustment mechanism is including: an adjusting circular plate 55, a fan-shaped through groove 56, an annular positioning plate 57 and a fan-shaped tooth 58, wherein the adjusting circular plate 55 is rotatably connected in the circular groove 51, four fan-shaped through grooves 56 are arranged on the side surface of the adjusting circular plate 55 in a circumferential array, the annular positioning plate 57 is welded on the cylindrical surface of the adjusting circular plate 55, the fan-shaped tooth 58 is welded on the side surface of the annular positioning plate 57, the annular positioning plate 57 is rotatably connected with the annular limiting groove 53, the fan-shaped tooth 58 is rotatably connected with the fan-shaped groove 54, the fan-shaped tooth 58 is meshed with the driving gear 25, the driving gear 25 drives the fan-shaped tooth 58 in the adjusting mechanism to rotate, the fan-shaped tooth 58 drives the annular positioning plate 57 to rotate along the annular limiting groove 53, the annular positioning plate 57 drives the adjusting circular groove 55 to rotate along the circular groove 51, so that the adjusting circular plate 55 drives the overlapping part of the fan-shaped through groove 56 and the fan-shaped air outlet 52 to gradually reduce the amount of hot air, when the fan-shaped through groove 56 and the fan-shaped air outlet 52 are completely staggered and distributed, the fan-shaped air outlet 52 is completely closed by the adjusting circular plate 55.
The side-mounting of baffle 5 has rotary mechanism, and rotary mechanism includes: the air-out device comprises an annular limiting plate 6, a cylinder 61, an annular bulge 62, a fixed circular plate 63, through holes 64, an annular positioning groove 65, a first gear ring 66, an air-out pipe 7, an air-out hole 71, a limiting ring 72 and a second gear ring 73, wherein the annular limiting plate 6 is welded on the side surface of a partition plate 5, the cylinder 61 is rotatably connected on the inner side of the annular limiting plate 6, the annular bulge 62 is arranged at one end of the cylinder 61, the fixed circular plate 63 is welded at the other end of the cylinder 61, four through holes 64 are formed in the side surface of the fixed circular plate 63 in a circumferential array, the annular positioning groove 65 is formed in the inner side of each through hole 64, the first gear ring 66 is welded on the outer side of the cylinder 61, the air-out pipe 7 is rotatably connected in the through holes 64, the air-out holes 71 are formed in the circumferential array at one end of the air-out pipe 7, the limiting ring 72 is welded on the outer side of the air-out pipe 7, the second gear ring 73 is welded at the other end of the air-out pipe 7, the annular bulge 62 is rotatably connected with the annular limiting plate 6, the cross section of annular limiting plate 6 becomes L shape setting, the spacing ring 72 rotates with annular positioning groove 65 and is connected, second gear ring 73 and the meshing of fixed gear 68, when drum 61 rotates, drum 61 drives annular bellying 62 and rotates along annular limiting plate 6, thereby guarantee the rotation that drum 61 can be stable, drum 61 drives fixed plectane 63 and rotates, fixed plectane 63 drives out tuber pipe 7 and rotates, it drives second gear ring 73 and rolls along fixed gear 68 to go out tuber pipe 7, second gear ring 73 drives out tuber pipe 7 and rotates simultaneously, it is along the rotation of through-hole 64 to go out tuber pipe 7 along with fixed plectane 63 revolution while, rotate the inside of discharging incubator 1 with hot-blast and moisture is even through going out tuber pipe 7, make the temperature and the humidity evenly distributed of incubator 1 inner chamber.
The side welding of baffle 5 has fixed column 67, and the one end welding of fixed column 67 has fixed gear 68, and power unit is installed in one side of rotary mechanism in the side of baffle 5, and power unit is including: the motor comprises a concave seat 8, a motor shaft 81 and a power gear 82, wherein the concave seat 8 is welded on the side surface of the partition plate 5, the motor shaft 81 is rotatably connected on the side surface of the concave seat 8, the power gear 82 is welded on one end of the motor shaft 81, the power gear 82 is meshed with the first gear ring 66, the power source of the motor shaft 81 is a motor, and the motor is embedded in the partition plate 5.
When the size of the fan-shaped air outlet 52 in the incubator 1 needs to be adjusted, firstly, the adjusting knob 38 is pressed inward, the adjusting knob 38 drives the movable column 36 to slide along the limiting rod 23, the movable column 36 drives the positioning toothed block 3 to slide along the limiting rod 23, so that the positioning toothed block 3 is separated from the fixed toothed block 33, meanwhile, the positioning toothed block 3 extrudes the locking spring 32, then, the adjusting knob 38 is rotated, the adjusting knob 38 drives the movable column 36, the limiting rod 23 and the circular plate 22 to rotate, the circular plate 22 drives the first helical gear 21 to rotate through the circular rod 2, the first helical gear 21 drives the second helical gear 24 to rotate, the second helical gear 24 drives the driving gear 25 to rotate through the pin shaft, the driving gear 25 drives the fan-shaped teeth 58 in the adjusting mechanism to rotate, the fan-shaped teeth 58 drives the annular positioning plate 57 to rotate along the annular limiting groove 53, the annular positioning plate 57 drives the adjusting circular plate 55 to rotate along the circular groove 51, the adjusting circular plate 55 drives the overlapped part of the fan-shaped through groove 56 and the fan-shaped air outlet 52 to gradually reduce, thereby reducing the amount of hot air, when the fan-shaped through groove 56 and the fan-shaped air outlet 52 are completely staggered and distributed, at the moment, the fan-shaped air outlet 52 is completely sealed by the adjusting circular plate 55, and then the incubator 1 is stopped to be heated, the amount of hot air in the air outlet pipe 7 can be conveniently adjusted through the matching of the arranged adjusting mechanism, the driving mechanism and the adjusting mechanism, thereby adjusting the heating amount, further achieving the temperature control of the inner part of the incubator 1, when the adjustment is completed, the pressing of the adjusting knob 38 is released, under the elastic force of the locking spring 32, the positioning tooth block 3 is clamped with the fixed tooth block 33, the driving mechanism is fixed through the arranged locking mechanism, the driving mechanism can not rotate, further, the adjusting mechanism is fixed, and the adjusting circular plate 55 is prevented from shaking at will, thereby ensuring the heating stability.
Through the cooperation of the humidifier 41 and the humidifying pipe 42, the moisture flows out along the humidifying pipe 42, through the cooperation of the heating device 43 and the air outlet fan 44, the hot air and the moisture are blown out along the fan-shaped air outlet 52, through the cooperation of the rotating mechanism and the power mechanism, the power gear 82 is driven to rotate through the motor shaft 81 in the power mechanism, the power gear 82 drives the first gear ring 66 and the cylinder 61 to rotate, the cylinder 61 drives the annular boss 62 to rotate along the annular limiting plate 6, thereby ensuring the stable rotation of the cylinder 61, the cylinder 61 drives the fixed circular plate 63 to rotate, the fixed circular plate 63 drives the air outlet pipe 7 to rotate, the air outlet pipe 7 drives the second gear ring 73 to roll along the fixed gear 68, meanwhile, the second gear ring 73 drives the air outlet pipe 7 to rotate, the air outlet pipe 7 drives the limiting ring 72 to rotate along the annular positioning groove 65, thereby ensuring the stable rotation of the air outlet pipe 7, hot-blast and moisture all flow along the exhaust vent 71 of tuber pipe 7, rotate the inside of discharging incubator 1 with hot-blast and moisture is even through tuber pipe 7, make the temperature and the humidity evenly distributed of incubator 1 inner chamber to guarantee the stable cultivation of bacterin.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (10)
1. A culture system for herpes zoster vaccines, comprising an incubator (1), characterized in that: the incubator is characterized in that a baffle (11) is welded on the front end face of the incubator (1), the front end face of the incubator (1) is connected with a chamber door (12) in a rotating mode on the side face of the baffle (11), an observation window (13) is embedded into the side face of the chamber door (12), an experiment support (14) is installed in an inner cavity of the incubator (1), a temperature monitor (15) and a humidity monitor (16) are installed on the upper end threads of the inner cavity of the incubator (1), a driving mechanism is installed on the inner side face of the baffle (11), a locking mechanism is arranged on the outer side face of the baffle (11), a fixing plate (4) is welded in the inner cavity of the incubator (1), a humidifier (41) is installed on the side face of the fixing plate (4), a humidifying pipe (42) is connected to the side face of the humidifier (41) through a pipe joint, and a heating device (43) is connected to one side, far away from the humidifier (41), of the fixing plate (4), through a bolt, a fan (44) is arranged on the inner side of the incubator (1), a partition plate (5) is welded in the inner cavity of the incubator (1), the side surface of the clapboard (5) is provided with a circular groove (51), the side surface of the circular groove (51) is provided with four fan-shaped air outlets (52) in a circumferential array, one end of the humidifying pipe (42) passes through the partition board (5) and extends out of the fan-shaped air outlet (52), the cylindrical surface of the circular groove (51) is provided with an annular limiting groove (53), the side surface of the annular limiting groove (53) is provided with a fan-shaped groove (54), an adjusting mechanism is arranged in the circular groove (51), a rotating mechanism is arranged on the side surface of the clapboard (5), a fixing column (67) is welded to the side face of the partition plate (5), a fixed gear (68) is welded to one end of the fixing column (67), and a power mechanism is installed on one side of the rotating mechanism on the side face of the partition plate (5).
2. A culture system for a herpes zoster vaccine according to claim 1, characterised in that: the driving mechanism comprises: round bar (2), first helical gear (21), circular slab (22), gag lever post (23), second helical gear (24) and drive gear (25), the side of baffle (11) is rotated and is connected with round bar (2), the one end welding of round bar (2) has first helical gear (21), the other end of round bar (2) passes baffle (11) and circular slab (22) welding, the side welding of circular slab (22) has gag lever post (23), the side meshing of first helical gear (21) has second helical gear (24), the side of second helical gear (24) has drive gear (25) through round pin hub connection.
3. A culture system for a herpes zoster vaccine according to claim 2, characterised in that: the driving gear (25) is arranged in the partition board (5), and the driving gear (25) is rotationally connected with the partition board (5) through a pin shaft.
4. A culture system for herpes zoster vaccine according to claim 2, characterised in that: the locking mechanism comprises: the positioning tooth block (3), the rectangular groove (31), the locking spring (32), the fixed tooth block (33), the guide round hole (34), the sector plate (35), the movable column (36), the guide groove (37) and the adjusting knob (38), wherein the positioning tooth block (3) is arranged on the side surface of the circular plate (22), the rectangular groove (31) is formed in the side surface of the positioning tooth block (3), the locking spring (32) is welded on the side surface of the positioning tooth block (3), the fixed tooth block (33) is clamped on the side surface of the positioning tooth block (3), the sector plates (35) are symmetrically welded on the upper portion and the lower portion of the side surface of the fixed tooth block (33), the sector plates (35) are welded with the baffle plate (11), the guide round hole (34) is formed in the side surface of the fixed tooth block (33), the movable column (36) is welded on the side surface of the positioning tooth block (3), and the guide groove (37) is formed in a penetrating mode at one end of the movable column (36), one end of the movable column (36) penetrates through the guide round hole (34) and is welded with the adjusting knob (38).
5. A culture system for herpes zoster vaccine according to claim 4, characterised in that: the side that location tooth piece (3) and fixed tooth piece (33) are a circular piece becomes the circumference array and has seted up the skewed tooth, rectangular channel (31) and guide way (37) are passed in proper order to the one end of gag lever post (23), and gag lever post (23) and rectangular channel (31), guide way (37) sliding connection.
6. A culture system for a herpes zoster vaccine according to claim 1, characterised in that: the adjustment mechanism comprises: the adjustable adjusting disc is characterized by comprising an adjusting disc (55), a fan-shaped through groove (56), an annular positioning plate (57) and fan-shaped teeth (58), wherein the adjusting disc (55) is connected in the circular groove (51) in a rotating mode, the four fan-shaped through grooves (56) are formed in the side face of the adjusting disc (55) in a circumferential array mode, the annular positioning plate (57) is welded on the cylindrical surface of the adjusting disc (55), and the fan-shaped teeth (58) are welded on the side face of the annular positioning plate (57).
7. A culture system for a herpes zoster vaccine according to claim 6, characterised in that: the annular positioning plate (57) is rotatably connected with the annular limiting groove (53), the sector gear (58) is rotatably connected with the sector groove (54), and the sector gear (58) is meshed with the driving gear (25).
8. A culture system for a herpes zoster vaccine according to claim 1, characterised in that: the rotary mechanism comprises: the air conditioner comprises an annular limiting plate (6), a cylinder (61), an annular boss (62), a fixed circular plate (63), a through hole (64), an annular positioning groove (65), a first gear ring (66), an air outlet pipe (7), an air outlet hole (71), a limiting ring (72) and a second gear ring (73), wherein the annular limiting plate (6) is welded on the side surface of a partition plate (5), the cylinder (61) is rotatably connected on the inner side of the annular limiting plate (6), the annular boss (62) is arranged at one end of the cylinder (61), the fixed circular plate (63) is welded at the other end of the cylinder (61), four through holes (64) are formed in the side surface of the fixed circular plate (63) in a circumferential array, the annular positioning groove (65) is formed in the inner side of the through hole (64), the first gear ring (66) is welded on the outer side of the cylinder (61), the air outlet pipe (7) is rotatably connected in the through hole (64), the one end of going out tuber pipe (7) becomes the circumference array and has seted up exhaust vent (71), the outside welding of going out tuber pipe (7) has spacing ring (72), the other end welding of going out tuber pipe (7) has second gear ring (73).
9. A culture system for a herpes zoster vaccine according to claim 8, characterised in that: annular bellying (62) rotate with annular limiting plate (6) and are connected, the cross section of annular limiting plate (6) becomes L shape and sets up, spacing ring (72) rotate with annular positioning groove (65) and are connected, second gear ring (73) and fixed gear (68) meshing.
10. A culture system for a herpes zoster vaccine according to claim 8, characterised in that: the power mechanism comprises: concave seat (8), motor shaft (81) and power gear (82), the side welding of baffle (5) has concave seat (8), the side rotation of concave seat (8) is connected with motor shaft (81), the one end welding of motor shaft (81) has power gear (82), power gear (82) and first gear ring (66) meshing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN202210303950.6A CN114606116A (en) | 2022-03-25 | 2022-03-25 | Culture system for herpes zoster vaccine |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210303950.6A CN114606116A (en) | 2022-03-25 | 2022-03-25 | Culture system for herpes zoster vaccine |
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| CN114606116A true CN114606116A (en) | 2022-06-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202210303950.6A Pending CN114606116A (en) | 2022-03-25 | 2022-03-25 | Culture system for herpes zoster vaccine |
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Cited By (1)
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| CN116655748A (en) * | 2023-02-28 | 2023-08-29 | 易慧生物技术(上海)有限公司 | Truncated varicella-zoster virus gE protein and application thereof |
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