CN114601481A - Surface electromyogram signal processing system and method - Google Patents
Surface electromyogram signal processing system and method Download PDFInfo
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- CN114601481A CN114601481A CN202210436776.2A CN202210436776A CN114601481A CN 114601481 A CN114601481 A CN 114601481A CN 202210436776 A CN202210436776 A CN 202210436776A CN 114601481 A CN114601481 A CN 114601481A
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
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- A—HUMAN NECESSITIES
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- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/389—Electromyography [EMG]
- A61B5/395—Details of stimulation, e.g. nerve stimulation to elicit EMG response
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
- A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
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Abstract
The embodiment of the invention provides a surface electromyogram signal processing system and a method, wherein in the system, a processing device determines the value of a target electromyogram signal according to the surface electromyogram signal in a preset time window after the first clock signal is delayed in a preset manner after receiving a first clock signal sent by a magnetic field generating device and the surface electromyogram signal sent by an electromyogram collecting device. The method extracts the value of the target electromyographic signal in the preset time window expected to generate the target electromyographic signal, can effectively reduce the influence of interference such as pulse interference, energy charging interference, interference generated by hand movement and the like on the identification of the target electromyographic signal, and improves the accuracy of acquiring the value of the target electromyographic signal.
Description
Technical Field
The embodiment of the invention relates to the technical field of medical equipment, in particular to a surface electromyographic signal processing system and method.
Background
Magnetic stimulation is a non-invasive research and treatment method which utilizes a pulsed magnetic field to act on the central nervous system, changes the membrane potential of cortical nerve cells, generates induced current, and influences the metabolism and neuroelectric activity in the brain, thereby causing a series of physiological and biochemical reactions. Magnetic Stimulation may be applied to the brain, or peripheral nerves, and is called Transcranial Magnetic Stimulation (TMS).
Prior to treating a patient with transcranial magnetic stimulation, a resting motion threshold of the patient needs to be measured to determine a stimulation intensity at which transcranial magnetic stimulation is to be administered to the patient. Wherein, the resting state movement threshold refers to the minimum stimulation intensity corresponding to the Motion Evoked Potential (MEP) of the thumb extended potential with the wave amplitude exceeding 50 microvolts induced for at least 5 times in 10 times of magnetic stimulation by using transcranial magnetic stimulation to the motor cortex of the brain of the patient in the resting state.
In practical applications, the collected surface electromyography signals include various interference signals in addition to the target electromyography signal of the patient: for example, pulse interference generated when the stimulation coil performs magnetic stimulation, charging interference generated when the magnetic field generating device is charged by a capacitor, interference generated by hand motion of a patient, white noise interference, and the like. The pulse interference, the energy charging interference and the interference amplitude generated by hand movement are large, so that the recognition of the surface electromyographic signal value of the patient is influenced, and the value of the obtained target electromyographic signal is inaccurate.
Disclosure of Invention
The embodiment of the invention provides a surface electromyographic signal processing system and method, aiming at overcoming the problem that the numerical value of a target electromyographic signal acquired by the prior art is inaccurate.
In a first aspect, an embodiment of the present invention provides a surface electromyography signal processing system, including: the device comprises a magnetic field generating device, a stimulating coil, a myoelectricity collecting device and a processing device; the magnetic field generating device is connected with the stimulating coil, and the processing device is respectively in communication connection with the magnetic field generating device and the myoelectricity collecting device;
the magnetic field generating device is used for sending a first clock signal when the discharge circuit switch is closed to the processing device when the discharge circuit switch is closed;
the myoelectric acquisition device is used for sending the acquired surface myoelectric signals to the processing device;
the processing device is used for determining the value of a target electromyographic signal according to the surface electromyographic signal in a preset time window after the first clock signal is delayed in a preset manner after the first clock signal sent by the magnetic field generating device and the surface electromyographic signal sent by the electromyographic signal collecting device are received; the magnetic field generating device, the myoelectricity collecting device and the processing device are clock pre-synchronous.
Optionally, the preset time window contains a complete signal of the target electromyogram signal.
Optionally, the preset time window includes a start signal of the target electromyogram signal.
Optionally, the system further comprises: a display device;
the display device is in communication connection with the processing device;
and the display device is used for receiving and displaying the plurality of target electromyographic signals sent by the processing device.
In a second aspect, an embodiment of the present invention provides a surface electromyogram signal processing method, where the method is applied to a magnetic field generating device, and the method includes:
when closing the discharge circuit switch, a first clock signal at the time of closing the discharge circuit switch is sent to a processing device.
In a third aspect, an embodiment of the present invention provides a surface electromyography signal processing method, where the method is applied to an electromyography acquisition device, and the method includes:
collecting surface electromyographic signals of a patient;
and sending the collected surface electromyographic signals to a processing device.
In a fourth aspect, an embodiment of the present invention provides a surface electromyogram signal processing method, where the method is applied to a processing apparatus, and the method includes:
receiving a first clock signal sent by a magnetic field generating device;
receiving a surface electromyographic signal sent by an electromyographic acquisition device;
determining a value of a target electromyographic signal according to the surface electromyographic signal in a preset time window after the first clock signal is delayed in a preset mode; the magnetic field generating device, the myoelectricity collecting device and the processing device are clock pre-synchronous.
Optionally, the preset time window contains a complete signal of the target electromyogram signal.
Optionally, the preset time window includes a start signal of the target electromyogram signal.
In a fifth aspect, an embodiment of the present invention provides a surface electromyography signal processing method, where the method is applied to a display device, and the method includes:
and receiving and displaying a plurality of target electromyographic signals sent by the processing device.
In the system, after receiving a first clock signal sent by a magnetic field generating device and a surface electromyographic signal sent by an electromyographic signal collecting device, a processing device determines a numerical value of a target electromyographic signal according to the surface electromyographic signal in a preset time window after a preset delay of the first clock signal. The method extracts the value of the target electromyographic signal in the preset time window expected to generate the target electromyographic signal, can effectively reduce the influence of interference such as pulse interference, energy charging interference, interference generated by hand movement and the like on the identification of the target electromyographic signal, and improves the accuracy of acquiring the value of the target electromyographic signal.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the description of the embodiments or the prior art will be briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.
FIG. 1 is a schematic diagram of a transcranial magnetic stimulation circuit in accordance with an example embodiment of the invention;
fig. 2 is a schematic structural diagram of a surface electromyogram signal processing system according to an embodiment of the present invention;
FIG. 3 is a schematic diagram of a surface electromyography signal provided by an embodiment of the invention;
FIG. 4 is a schematic diagram of another surface electromyography provided by an embodiment of the invention;
fig. 5 is a schematic structural diagram of another surface electromyogram signal processing system according to an embodiment of the present invention;
fig. 6 is a schematic flow chart of a surface electromyogram signal processing method according to an embodiment of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, but not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
For better understanding of the technical solution of the present invention, the terms related to the present invention are explained as follows:
surface electromyography (sEMG): is an electrical signal accompanied by muscle contraction, and is an important method for non-invasively detecting muscle activity on the body surface.
Target electromyographic signals: refers to the surface electromyographic signals generated by the motor cortex of the brain of a patient when the motor cortex is subjected to transcranial magnetic stimulation.
For better understanding of the technical solution of the present invention, the principle and timing of the transcranial magnetic stimulation circuit designed by the present invention are explained as follows:
fig. 1 is a schematic diagram of a transcranial magnetic stimulation circuit, as shown in fig. 1, in accordance with an example embodiment of the present invention. Illustratively, the timing of the operation of the transcranial magnetic stimulation circuit is as follows:
in the initial state, the switch S1 and the switch S2 are in the off state.
At a first time, the switch S1 is closed, the charging circuit is switched on, and the DC power supply DC charges the capacitor C.
At a second time, the capacitor C is charged and the switch S1 is opened.
At the third moment, the switch S2 is closed, the discharging circuit is turned on, the capacitor C, the resistor R and the inductance L formed by winding the stimulating coil form an RLC oscillator circuit, and the stimulating coil generates an alternating magnetic field to magnetically stimulate the patient.
At the fourth moment, the switch S2 is turned off, and one pulse magnetic stimulation is completed.
In the above operation sequence, the time when the switch S2 of the discharge circuit is closed is the start time when the magnetic stimulation is applied to the patient. When the stimulation coil applies magnetic stimulation with enough stimulation intensity to the motor cortex of the brain of the patient, the motor cortex of the brain is activated to generate action potential, the action potential is transmitted to the abductor hallucis brevis of the patient along a nerve path, and the action potential can be captured by the electromyographic acquisition device, namely target electromyographic signals. Wherein, the action potential is transmitted to the abductor hallucis brevis by the brain, which usually takes 15 ms to 30 ms, the width of the collected target electromyographic signal is usually 15 ms to 30 ms, and the width of the pulse interference captured by the electromyographic collecting device is usually 1 ms to 3 ms in a closed room.
The embodiment of the invention provides a surface electromyographic signal processing system and method, wherein the time for implementing magnetic stimulation corresponds to the acquired surface electromyographic signal, and the value of the target electromyographic signal is extracted in a preset time window for predicting generation of the target electromyographic signal.
The technical solutions of the present invention will be described in detail below with reference to several specific embodiments, which may be combined with each other, and the same or similar concepts or processes may not be described in detail in some embodiments.
Fig. 2 is a schematic structural diagram of a surface electromyogram signal processing system according to an embodiment of the present invention. As shown in fig. 2, the surface electromyogram signal processing system may include: a magnetic field generating device 310, a stimulating coil 320, a myoelectricity collecting device 200 and a processing device 100.
Wherein the magnetic field generating device 310 is connected to the stimulation coil 320.
It should be noted that copper connections with large cross-sectional areas are typically used between the magnetic field generating device 310 and the stimulation coil 320 to support the transfer of several thousand amperes of pulsed current between the magnetic field generating device 310 and the stimulation coil 320.
The processing device 100 is respectively connected with the magnetic field generating device 310 and the myoelectricity collecting device 200 in a communication way. The specific connection mode is not limited in the embodiments of the present invention.
And a magnetic field generating device 310 for transmitting a first clock signal when the discharge circuit switch is closed to the processing device 100 when the discharge circuit switch is closed.
Taking the circuit shown in fig. 1 as an example, switch S2 is closed at the third time.
In a possible implementation manner, when the magnetic field generating device 310 closes the discharge circuit switch, the first clock signal sent to the processing device 100 may be a data packet containing a timestamp, and the processing device 100 may analyze, according to the received data packet, a corresponding time when the magnetic field generating device 310 closes the discharge circuit switch. In this alternative mode, the magnetic field generating device 310, the myoelectric acquisition device 200, and the processing device 100 are clock pre-synchronized.
In another possible implementation, the first clock signal sent by the magnetic field generating device 310 to the processing device 100 when the discharge circuit switch is closed may be a level signal that can be recognized by the processing device 100. After receiving the level signal, the processing device 100 determines the time when the level signal is received as the time when the magnetic field generating device 310 closes the discharge circuit switch. In this alternative mode, the myoelectric acquisition device 200 and the processing device 100 are clock pre-synchronized, and the magnetic field generating device 310 may not be synchronized.
And the myoelectric acquisition device 200 is used for sending the acquired surface myoelectric signal to the processing device 100.
The method for acquiring the surface electromyogram signal of the patient by the electromyogram acquisition device 200 is the prior art, and is not described in detail in this embodiment.
The processing device 100 is configured to, after receiving the first clock signal sent by the magnetic field generating device 310 and the surface electromyogram signal sent by the electromyogram acquisition device 200, determine a value of the target electromyogram signal according to the surface electromyogram signal within a preset time window after a preset delay of the first clock signal.
Wherein the magnitude of the predetermined delay is determined according to the duration of the action potential transmitted from the brain to the abductor hallucis brevis muscle and the width of the captured pulse interference. For example, the preset delay may be 15 ms, 13 ms, or 10 ms, etc., so as to ensure that the target myoelectric signal is within the preset time window and avoid covering the pulse interference within the preset time window.
In a possible implementation manner, a complete signal of the target electromyogram signal may be included in the preset time window.
Since it generally takes 15 to 30 milliseconds for action potential to be transferred to the abductor hallucis brevis by the brain, the width of the target electromyogram signal captured by the electromyogram acquisition device is generally 15 to 30 milliseconds. Thus, the preset time window may include a transmission time window and a signal time window. Exemplarily, fig. 3 is a schematic diagram of a surface electromyogram signal provided by an embodiment of the present invention. As shown in fig. 3, when the preset delay is 15 msec, 15 msec to 60 msec from the first clock signal may be set as the preset time window; for another example, when the preset delay is 10 ms, 10 ms to 65 ms from the first clock signal may be set as the preset time window.
In this way, the complete signal of the target electromyographic signal is contained in a preset time window, and the value of the target electromyographic signal can be found by the prior art. Generally, the value of the target electromyogram signal is a peak-to-peak value of the target electromyogram signal.
In another possible implementation manner, the preset time window contains a start signal of the target electromyography signal.
In this manner, the predetermined time window may comprise only a transmission time window. Exemplarily, fig. 4 is a schematic diagram of another surface electromyography signal provided by the embodiment of the present invention. As shown in fig. 4, when the preset delay is 15 msec, 15 msec to 30 msec from the first clock signal may be set as the preset time window; for another example, when the preset delay is 10 ms, 10 ms to 35 ms from the first clock signal may be set as the preset time window.
In this manner, the start signal of the target electromyogram signal is contained in the preset time window, and the first peak value of the target electromyogram signal and all peak values located within a certain range after the peak value can be found by setting a reasonable threshold value. Wherein the range may be determined by the width of the target electromyogram signal. Further, the value of the target electromyogram signal may be obtained according to all the obtained peak values.
It should be understood that, in the above embodiments, the magnetic field generating device, the myoelectricity collecting device, and the processing device are clock pre-synchronized, and the clock pre-synchronization mode is the prior art, and is not described in detail in this embodiment.
In the system for processing the surface electromyogram signal provided by the embodiment of the invention, after receiving the first clock signal sent by the magnetic field generating device and the surface electromyogram signal sent by the electromyogram collecting device, the processing device determines the value of the target electromyogram signal according to the surface electromyogram signal in the preset time window after the preset delay of the first clock signal. The method extracts the value of the target electromyographic signal in the preset time window expected to generate the target electromyographic signal, can effectively reduce the influence of interference such as pulse interference, energy charging interference, interference generated by hand movement and the like on the identification of the target electromyographic signal, and improves the accuracy of acquiring the value of the target electromyographic signal.
Fig. 5 is a schematic structural diagram of another surface electromyography signal processing system according to an embodiment of the present invention. On the basis of fig. 2, as shown in fig. 5, the system may further include: a display device 400.
Wherein the display device 400 is communicatively connected to the processing device 100.
The display device 400 is used for receiving and displaying a plurality of target electromyographic signals sent by the processing device 100.
According to the method provided by the embodiment of the invention, the target electromyographic signals extracted from the surface electromyographic signals are displayed, so that whether the current transcranial magnetic stimulation intensity is a resting state movement threshold value or not can be accurately and clearly indicated to a clinician, and the use experience of the clinician is improved.
Fig. 6 is a schematic flow chart of a surface electromyogram signal processing method according to an embodiment of the present invention, and as shown in fig. 6, the method may be applied to the surface electromyogram signal processing system shown in fig. 5, for example. The method can comprise the following steps:
s101, when the discharge circuit switch is closed, the magnetic field generating device 310 transmits a first clock signal to the processing device 100 when the discharge circuit switch is closed. Correspondingly, the processing device 100 receives the first clock signal transmitted by the magnetic field generating device 310.
S102, the myoelectric acquisition device 200 acquires surface myoelectric signals of the patient.
S103, the myoelectric acquisition device 200 sends the acquired surface myoelectric signal to the processing device 100. Correspondingly, the processing device 100 receives the surface electromyogram signal sent by the electromyogram acquisition device 200.
S104, the processing device 100 determines the value of the target electromyographic signal according to the surface electromyographic signal in the preset time window after the first clock signal is delayed in a preset mode.
Wherein the magnetic field generating device 310, the myoelectric collecting device 200, and the processing device 100 are clock pre-synchronized.
In a possible implementation manner, the preset time window contains a complete signal of the target electromyogram signal.
In another possible implementation manner, the preset time window contains a start signal of the target electromyography signal.
S105, the display device 400 receives the plurality of target electromyographic signals sent by the processing device 100.
S106, the display device 400 displays a plurality of target electromyographic signals.
According to the surface electromyogram signal processing method provided by the embodiment of the invention, after the processing device receives the first clock signal sent by the magnetic field generating device and the surface electromyogram signal sent by the electromyogram collecting device, the value of the target electromyogram signal is determined according to the surface electromyogram signal in the preset time window after the preset delay of the first clock signal. The method extracts the value of the target electromyographic signal in the preset time window expected to generate the target electromyographic signal, can effectively reduce the influence of interference such as pulse interference, energy charging interference, interference generated by hand movement and the like on the identification of the target electromyographic signal, and improves the accuracy of acquiring the value of the target electromyographic signal.
Finally, it should be noted that: the above embodiments are only used to illustrate the technical solution of the present invention, and not to limit the same; while the invention has been described in detail and with reference to the foregoing embodiments, it will be understood by those skilled in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some or all of the technical features may be equivalently replaced; and the modifications or the substitutions do not make the essence of the corresponding technical solutions depart from the scope of the technical solutions of the embodiments of the present invention.
Claims (10)
1. A surface electromyography signal processing system, comprising: the device comprises a magnetic field generating device, a stimulating coil, a myoelectricity collecting device and a processing device; the magnetic field generating device is connected with the stimulating coil, and the processing device is respectively in communication connection with the magnetic field generating device and the myoelectricity collecting device;
the magnetic field generating device is used for sending a first clock signal when the discharge circuit switch is closed to the processing device when the discharge circuit switch is closed;
the myoelectric acquisition device is used for sending the acquired surface myoelectric signals to the processing device;
the processing device is used for determining the value of a target electromyographic signal according to the surface electromyographic signal in a preset time window after the first clock signal is delayed in a preset manner after the first clock signal sent by the magnetic field generating device and the surface electromyographic signal sent by the electromyographic signal collecting device are received; the magnetic field generating device, the myoelectricity collecting device and the processing device are clock pre-synchronous.
2. The system according to claim 1, characterized in that said preset time window contains the complete signal of said target electromyographic signal.
3. The system according to claim 1, wherein the preset time window comprises a start signal of a target electromyographic signal.
4. The system according to any one of claims 1-3, further comprising: a display device;
the display device is in communication connection with the processing device;
the display device is used for receiving and displaying a plurality of target electromyographic signals sent by the processing device.
5. A surface electromyography signal processing method applied to a magnetic field generating device, the method comprising:
when closing the discharge circuit switch, a first clock signal at the time of closing the discharge circuit switch is sent to a processing device.
6. A surface electromyography signal processing method applied to an electromyography acquisition device, the method comprising:
collecting surface electromyographic signals of a patient;
and sending the collected surface electromyographic signals to a processing device.
7. A surface electromyography signal processing method applied to a processing device, the method comprising:
receiving a first clock signal sent by a magnetic field generating device;
receiving a surface electromyographic signal sent by an electromyographic acquisition device;
determining a value of a target electromyographic signal according to the surface electromyographic signal in a preset time window after the first clock signal is delayed in a preset mode; the magnetic field generating device, the myoelectricity collecting device and the processing device are clock pre-synchronous.
8. The method according to claim 7, characterized in that said preset time window contains the complete signal of said target electromyographic signal.
9. The method according to claim 7, characterized in that the preset time window contains a start signal of a target electromyographic signal.
10. A surface electromyography signal processing method applied to a display device, the method comprising:
and receiving and displaying a plurality of target electromyographic signals sent by the processing device.
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