CN114600876A - Mosquito killing method, poison bait and device - Google Patents

Mosquito killing method, poison bait and device Download PDF

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Publication number
CN114600876A
CN114600876A CN202210249177.XA CN202210249177A CN114600876A CN 114600876 A CN114600876 A CN 114600876A CN 202210249177 A CN202210249177 A CN 202210249177A CN 114600876 A CN114600876 A CN 114600876A
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CN
China
Prior art keywords
mosquitoes
channel
ivermectin
medicine pool
mosquito
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Pending
Application number
CN202210249177.XA
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Chinese (zh)
Inventor
郑爱华
张知彬
刘明
温丹
丁利民
李晓叶
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Institute of Zoology of CAS
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Institute of Zoology of CAS
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Priority to CN202210249177.XA priority Critical patent/CN114600876A/en
Publication of CN114600876A publication Critical patent/CN114600876A/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/002Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing a foodstuff as carrier or diluent, i.e. baits
    • A01N25/006Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing a foodstuff as carrier or diluent, i.e. baits insecticidal
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01MCATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M1/00Stationary means for catching or killing insects
    • A01M1/02Stationary means for catching or killing insects with devices or substances, e.g. food, pheronones attracting the insects
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01MCATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M1/00Stationary means for catching or killing insects
    • A01M1/20Poisoning, narcotising, or burning insects
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system

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  • Life Sciences & Earth Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Insects & Arthropods (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention discloses a mosquito killing method, poison bait and a device. The mosquito killing poison bait consists of ivermectin and mosquito nutrient solution. The mosquito killing method of the invention utilizes the poison bait to attract the mosquitoes to eat so as to kill the mosquitoes. The mosquito killing device comprises a base, a plurality of cotton cores for draining poison baits and a plurality of artificial flowers for attracting mosquitoes; the top of the base is provided with a medicine pool; a plurality of channels are arranged around the medicine pool and are communicated with the bottom of the medicine pool; each cotton core is filled in the channel from inside to outside from the bottom of each channel and exposes out of the opening end of the channel; each false flower is fixed at the open end of each channel, and the petals of each false flower are arranged around the periphery of the open end of each channel. The invention adopts ivermectin to kill mosquitoes, has good stability, is effective for a long time, is safe and nontoxic and can kill the mosquitoes efficiently; the artificial flower feeder has bright flower color, gives off the smell of cane sugar and honey, has great attraction to mosquitoes, and attracts the mosquitoes to eat for multiple times so as to kill the mosquitoes efficiently.

Description

Mosquito killing method, poison bait and device
Technical Field
The invention relates to the field of pest control hygiene, in particular to a method for designing a bait formulation by using ivermectin for indoor mosquito killing.
Background
Sanitary pests can harm human life through various modes such as harassment, bite, parasitism and the like, and pathogens can be transmitted to cause epidemic outbreaks such as plague, typhoid fever, malaria and the like, thereby seriously threatening the life safety of people.
The original mosquito killing methods mainly comprise electric mosquito-repellent incense liquid, mosquito-repellent incense, insecticidal spray and mosquito killing lamps, and the methods have limitations. The electric mosquito-repellent incense liquid and the mosquito-repellent incense have volatility and heavy smell and are harmful to infants, pregnant women and sensitive people. ② the insecticidal spray has obvious toxicity to the nervous system of human body, and the long-term contact (even low dose) can cause cranial nerve paralysis, abnormal sensation, dizziness, headache and other nervous symptoms. But the insecticidal components belonging to organophosphorus, organochlorine and carbamate have higher toxicity to human and livestock. The mosquito trapping efficiency of the mosquito killer lamp is low, the phenomenon that the skin is aged is more serious after the mosquito killer lamp is used for a long time, and the electric shock danger is easily caused. Therefore, a safe, nontoxic and efficient dosage form is needed to achieve the mosquito killing effect.
Ivermectin: avermectins are sixteen-membered macrocyclic lactone compounds with insecticidal, acaricidal and nematicidal activities, first developed by noose et al, university of north-li, japan and Merck, usa, and produced by fermentation of Streptomyces avermitilis (Streptomyces avermitilis). The ivermectin is a derivative of the abamectin, is a novel broad-spectrum, high-efficiency and low-toxicity antibiotic anti-parasitic drug, and has good expelling and killing effects on parasites in vivo and in vitro, particularly nematodes and arthropods.
Disclosure of Invention
The invention aims to provide a mosquito killing method, poison bait and a device, wherein ivermectin is used for killing mosquitoes, and the method is safe, nontoxic and capable of killing mosquitoes efficiently.
In a first aspect, the invention protects the use of ivermectin in killing mosquitoes.
In a second aspect, the invention provides a poison bait for killing mosquitoes, which consists of ivermectin and mosquito nutrient solution.
Further, the mosquito nutrient solution consists of cane sugar, honey and water.
Further, the concentration of ivermectin in the bait is 34 μmol/L.
As an example, the mass percentage of the sucrose in the poison bait is 5-10%, such as 5% or 10%;
the mass percentage of the honey in the poison bait is 5-10%, such as 5% or 10%.
In a third aspect, the invention provides a method of killing mosquitoes, comprising attracting mosquitoes to eat a bait according to any one of the above to kill the mosquitoes.
Further, the poison bait with the mass of 1.5mg of ivermectin is placed indoors with the length of 20-40 cubic meters (such as the length of 3.3 meters, the width of 3.2 meters and the height of 3 meters).
In a fourth aspect, the invention provides a device for killing mosquitoes with poison baits, which comprises a base, a plurality of cotton cores for draining the poison baits and a plurality of false flowers for attracting mosquitoes;
a medicine pool is arranged at the top of the base; a plurality of channels are arranged around the medicine pool and are communicated with the bottom of the medicine pool;
each cotton core is filled in the channel from inside to outside from the bottom of each channel and at least exposes out of the opening end of the channel;
each artificial flower is fixed at the opening end of each channel, and petals of each artificial flower are arranged around the periphery of the opening end of each channel.
Further, the diameter of the medicine pool is 3-5 cm, and the height of the medicine pool is 3-5 cm;
each channel has a diameter of 0.5-1.2 cm and a length of 5-15 cm;
each channel extends upwards from the bottom of the medicine pool, and the included angle between each channel and the medicine pool is 45-60 degrees;
each cotton core is at least exposed out of the opening end of the channel by 5 cm.
Furthermore, the plurality of channels are uniformly arranged around the medicine pool; the number of the false flowers is 4, and the colors are purple, yellow, blue and red respectively.
Further, the base is made of plastic, such as polypropylene (PP).
The invention has the following beneficial effects:
1. the ivermectin has good stability, is effective for a long time, and is simple to operate compared with spraying.
2. Is non-toxic because it is a drug per se. Is effective in treating and controlling Nissan disease. The concentration used in the invention is 0.03mg/ml, 50 ml of ivermectin sucrose honey solution is added into each small box, the total amount is 1.5mg, the dosage is lower than that of tablets for human use, and the safety is good.
3. Has no volatilization and no harm. For fumigation, such as mosquito coil and electric mosquito liquid.
4. High-efficiency killing mosquito.
5. The artificial flower feeder has bright flower color, gives off the smell of cane sugar and honey, has great attraction to mosquitoes, attracts the mosquitoes to take food for multiple times, and efficiently kills the mosquitoes.
Drawings
FIG. 1 shows the mosquito-killing effect of ivermectin with different concentrations in example 1 of the present invention.
FIG. 2 shows the effect of 34. mu. mol/L ivermectin bait on killing indoor mosquitoes in example 2 of the present invention.
Fig. 3 is a schematic structural view of an artificial flower mosquito-luring mosquito killer in embodiment 3 of the invention. Each label is as follows: 1-a base; 2-a medicine pool; 3-a channel; 4-cotton core; 5-false flower.
Detailed Description
The present invention is described in further detail below with reference to specific embodiments, which are given for the purpose of illustration only and are not intended to limit the scope of the invention. The examples provided below serve as a guide for further modifications by a person skilled in the art and do not constitute a limitation of the invention in any way.
The experimental methods used in the following examples are all conventional methods unless otherwise specified; the materials, reagents and the like used are commercially available unless otherwise specified.
The ivermectin manufacturer in the following examples is a shenlong veterinary drug factory in northern Guangxi, and the product name is ivermectin solution, and the specification is 100 ml.
Preparing a sucrose honey solution: dissolving sucrose and honey in water to prepare an aqueous solution containing 5% by mass of sucrose (0.05 g/mL (mass: volume)) and 5% by mass of honey (0.05 g/mL (mass: volume)) for later use.
Example 1 selection of Ivermectin concentration in bait
The 0.3% ivermectin stock solution is diluted by a solution containing 5% sucrose and 5% honey according to 100 times, 1000 times and 10000 times, so that the final concentration of the ivermectin reaches 34 mu mol/L, 3.4 mu mol/L and 0.34 mu mol/L respectively. 50 female mosquitoes were placed in each cage, and different concentrations of ivermectin sucrose honey solution were given, and the control group was normal 5% sucrose and 5% honey solution without ivermectin. The mosquitoes were cultured in an artificial climate box at a humidity of 60%, a temperature of 28 ℃ and a daily illumination time of 12 hours, and the survival number of the mosquitoes was observed and recorded every day, and the results are shown in fig. 1, in the experimental group with the ivermectin concentration of 34 mu mol/L, 60% of the mosquitoes were killed on day 3, and all the mosquitoes were killed on day 6. This indicates that the ivermectin and sucrose honey mixed solution can successfully kill mosquitoes.
Example 2 killing indoor mosquitoes with poison bait
A stock solution of 0.3% (mass: volume) ivermectin was diluted 100-fold with a solution containing 5% (mass: volume) sucrose and 5% (mass: volume) honey to give a final concentration of ivermectin of 34. mu. mol/L. 400 female mosquitoes are placed in a room with the length of 3.3 meters, the width of 3.2 meters and the height of 3 meters, cotton is added into two small round boxes with the diameter of 6 centimeters and the height of 7 centimeters, wherein the cotton in one round box is added with an ivermectin cane sugar honey solution with the concentration of 34 mu mol/L, and the cotton in the other round box is added with normal 5 percent cane sugar and 5 percent honey solution. Both round boxes in the control room were filled with normal 5% sucrose and 5% honey solutions. The number of mosquitoes surviving was observed and recorded, and as a result, 92% of mosquitoes were killed on day 3 as shown in fig. 2. This shows that the mixed solution of ivermectin and sucrose honey can successfully kill mosquitoes without affecting the feeding ability of mosquitoes.
Example 3 Artificial flower mosquito-luring and killing device
As shown in fig. 3, the artificial flower mosquito-luring mosquito killer comprises a base 1 made of PP, four cotton cores 2 for guiding poison baits and four artificial flowers 3 which are purple, yellow, blue and red respectively and are used for luring mosquitoes;
the upper surface of the base 1 is circular with the diameter of 5 cm, the lower surface is circular with the diameter of 10 cm, the longitudinal section is trapezoidal, and the height of the base is 4 cm; a medicine pool 2 with the diameter of 4 cm and the height of 4 cm is arranged at the top of the base 1; two channels 3 with the diameter of 1.2 cm and the length of 5 cm are arranged around the medicine pool 2, and the two channels 3 are both communicated with the bottom of the medicine pool 2; each channel 3 extends upwards from the bottom of the medicine pool 2, and the included angle between each channel and the medicine pool is 45 degrees;
each cotton core 4 is filled in the channel from the bottom of each channel 3 to the outside and exposes the opening end of the channel by 5 cm;
each false flower 5 is fixed at the open end of each channel 3, and the petals of each false flower 5 are arranged around the periphery of the open end of each channel 3.
When the drug pool is used, poison bait is added into the drug pool, the cotton core absorbs water after the poison bait is added, and the odor of the cane sugar and the honey and the bright flowers attract mosquitoes to eat so as to kill the mosquitoes.
The mosquito killing effect is evaluated by taking the bait agent as an example, wherein the bait agent comprises 10% (mass: volume) of cane sugar, 10% (mass: volume) of honey and 0.003% (mass: volume) of ivermectin solution. Both round boxes in the control room were filled with normal 10% sucrose and 10% honey solutions. The observation records the survival number of mosquitoes, and the results are as follows: 100% of mosquitoes can be killed by the 3 rd day, which shows that the artificial flower attractant can improve the efficiency of killing mosquitoes.
The present invention has been described in detail above. It will be apparent to those skilled in the art that the invention can be practiced in a wide range of equivalent parameters, concentrations, and conditions without departing from the spirit and scope of the invention and without undue experimentation. While the invention has been described with reference to specific embodiments, it will be appreciated that the invention can be further modified. In general, this application is intended to cover any variations, uses, or adaptations of the invention following, in general, the principles of the invention and including such departures from the present disclosure as come within known or customary practice within the art to which the invention pertains. The use of some of the essential features is possible within the scope of the claims attached below.

Claims (10)

1. The application of ivermectin in killing mosquito is provided.
2. A poison bait for killing mosquitoes, which is characterized in that: it consists of ivermectin and mosquito nutrient solution.
3. A bait according to claim 2, wherein: the mosquito nutrient solution consists of cane sugar, honey and water.
4. A bait according to claim 3, wherein: the concentration of the ivermectin in the poison bait is 34 mu mol/L.
5. A method for killing mosquitoes comprising attracting mosquitoes to eat with the bait according to any one of claims 2 to 4 to kill the mosquitoes.
6. A method of killing mosquitoes according to claim 5, wherein: and placing the poison bait with the mass of 1.5mg of ivermectin in every 20-40 cubic meters indoors.
7. A device for killing mosquitoes with the bait according to any one of claims 2 to 4, comprising a base, a plurality of wicks for draining the bait and a plurality of artificial flowers for attracting mosquitoes;
a medicine pool is arranged at the top of the base; a plurality of channels are arranged around the medicine pool and are communicated with the bottom of the medicine pool;
each cotton core is filled in the channel from inside to outside from the bottom of each channel and exposes the opening end of the channel;
each artificial flower is fixed at the opening end of each channel, and petals of each artificial flower are arranged around the periphery of the opening end of each channel.
8. The apparatus of claim 7, wherein: the diameter of the medicine pool is 3-5 cm, and the height of the medicine pool is 3-5 cm;
each channel has a diameter of 0.5-1.2 cm and a length of 5-15 cm;
each channel extends upwards from the bottom of the medicine pool, and the included angle between each channel and the medicine pool is 45-60 degrees;
each cotton core is at least exposed out of the opening end of the channel by 5 cm.
9. The apparatus of claim 7 or 8, wherein: the plurality of channels are uniformly arranged around the medicine pool; the number of the false flowers is 4, and the colors are purple, yellow, blue and red respectively.
10. The apparatus according to any one of claims 7-9, wherein: the base is made of plastic.
CN202210249177.XA 2022-03-14 2022-03-14 Mosquito killing method, poison bait and device Pending CN114600876A (en)

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1229592A (en) * 1999-01-14 1999-09-29 毛广佳 Mosquito trap agent
CN104798751A (en) * 2015-04-16 2015-07-29 宁国市瑞来安有害生物防制有限责任公司 Mosquito and insect prevention and control device
CN205161659U (en) * 2015-11-11 2016-04-20 张雨丰 Kill mosquito device of mosquito of killing
CN107372516A (en) * 2017-07-26 2017-11-24 南通功成精细化工有限公司 A kind of hygienic biocide granule and preparation method thereof
WO2018037093A1 (en) * 2016-08-24 2018-03-01 Vestergaard Sa A method and substrate with abamectin and fenpyroximate for killing mosquitoes
CN112970488A (en) * 2021-02-05 2021-06-18 百色芒果研究院 Method for preventing and treating common cecidomyiia miscanthus
CN113519568A (en) * 2020-04-21 2021-10-22 刘波 Mosquito bait
US20210386065A1 (en) * 2020-06-10 2021-12-16 Valent Biosciences Llc Mixture of mectins and pyrethroids and uses thereof
TWM623565U (en) * 2021-09-01 2022-02-21 傑若德 哈里斯 Mosquito Killer

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1229592A (en) * 1999-01-14 1999-09-29 毛广佳 Mosquito trap agent
CN104798751A (en) * 2015-04-16 2015-07-29 宁国市瑞来安有害生物防制有限责任公司 Mosquito and insect prevention and control device
CN205161659U (en) * 2015-11-11 2016-04-20 张雨丰 Kill mosquito device of mosquito of killing
WO2018037093A1 (en) * 2016-08-24 2018-03-01 Vestergaard Sa A method and substrate with abamectin and fenpyroximate for killing mosquitoes
CN107372516A (en) * 2017-07-26 2017-11-24 南通功成精细化工有限公司 A kind of hygienic biocide granule and preparation method thereof
CN113519568A (en) * 2020-04-21 2021-10-22 刘波 Mosquito bait
US20210386065A1 (en) * 2020-06-10 2021-12-16 Valent Biosciences Llc Mixture of mectins and pyrethroids and uses thereof
CN112970488A (en) * 2021-02-05 2021-06-18 百色芒果研究院 Method for preventing and treating common cecidomyiia miscanthus
TWM623565U (en) * 2021-09-01 2022-02-21 傑若德 哈里斯 Mosquito Killer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
卢玉霞等: ""畜禽驱虫程序的误区与对策"", 《中国畜禽种业》 *

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