CN114558169A - Self-repairing nutrient injection and application method thereof - Google Patents

Self-repairing nutrient injection and application method thereof Download PDF

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Publication number
CN114558169A
CN114558169A CN202210196283.6A CN202210196283A CN114558169A CN 114558169 A CN114558169 A CN 114558169A CN 202210196283 A CN202210196283 A CN 202210196283A CN 114558169 A CN114558169 A CN 114558169A
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CN
China
Prior art keywords
nutrient injection
repairing
self
injection
nutrient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210196283.6A
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Chinese (zh)
Inventor
房一汀
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Jingjia Biotechnology Co ltd
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Beijing Jingjia Biotechnology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Beijing Jingjia Biotechnology Co ltd filed Critical Beijing Jingjia Biotechnology Co ltd
Priority to CN202210196283.6A priority Critical patent/CN114558169A/en
Publication of CN114558169A publication Critical patent/CN114558169A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/025Other specific inorganic materials not covered by A61L27/04 - A61L27/12
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/18Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/20Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/06Flowable or injectable implant compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/34Materials or treatment for tissue regeneration for soft tissue reconstruction

Abstract

The invention provides an autologous repair nutrient injection and an application method thereof, belonging to the technical field of beauty medicine. Comprises sodium chloride solution, collagen, PEG600, dimethylaminoethanol and cationic hyaluronic acid. The self-repairing nutrient injection and the application method thereof provided by the invention have the advantages of effectively tensioning the skin, preventing the skin from loosening and sagging, delaying aging, being safe and healthy, and simultaneously enabling the facial skin to achieve a full, compact, smooth and beautiful youthful vigor state.

Description

Self-repairing nutrient injection and application method thereof
Technical Field
The invention provides an autologous repair nutrient injection and an application method thereof, belonging to the technical field of beauty medicine.
Background
Beauty is a life style, and the desire for beauty varies more and more. Although the aesthetic looks of people are constantly changing, the pursuit of beauty is not always changed, thereby creating the beauty industry. Ever since the existence of human beings, there has been beauty treatment. The beauty treatment is to beautify the appearance of people. With the development of society and the improvement of science and technology, the beauty treatment is continuously changed and improved from content to form. In the cosmetic field, anti-aging is one of its most important components. When people age, the change of appearance is reflected in the aspect of face, and there are three main manifestations: wrinkles, prolapse, collapse. That is, the skin of people is aged loose with age, so that it is necessary to beautify, maintain and repair the skin of the face in order to make the face less afraid of aging.
For beautifying and maintaining, various modes such as external smearing, oral taking, injection beautifying and the like exist. The market of cosmetics for external application is coming to the fifth generation, namely the age of biological cosmetics, after the four generations of evolution and development of minerals, mutton fat, pure plants and chemical synthetic products. The first five generations of cosmetic products are collagen. Meanwhile, beauty lovers also try to supplement a large amount of collagen through food, health care products and the like, such as eating pig trotters or taking collagen oral liquid. However, the effects of both external use and internal use are difficult to rapidly and obviously realize, and the injection beauty has the problems of not long-term effect of absorbable injection and repeated injection and the problem of potential safety hazard of the non-absorbable injection. For repair and beauty, the human body has certain regeneration and repair capacity after skin is wounded. For example, when the wound field is small or the injury is light, repair can occur through the natural healing process. Therefore, the cosmetic effect of delaying skin aging can be achieved by utilizing self-repairing.
Disclosure of Invention
The self-repairing nutrient injection and the application method thereof provided by the invention have the advantages of effectively tensioning the skin, preventing the skin from loosening and sagging, delaying aging, being safe and healthy, and simultaneously enabling the facial skin to achieve a full, compact, smooth and beautiful youthful vigor state.
The invention provides an autologous repair nutrition injection which comprises a sodium chloride solution, collagen, PEG600, dimethylaminoethanol and cationic hyaluronic acid.
Further, the cationic hyaluronic acid is sodium hyaluronate gel. The method specifically comprises the following steps: 1-3% of sodium hyaluronate gel.
Further, the molecular weight of the sodium hyaluronate is 200 ten thousand daltons.
Further, the sodium chloride solution is sodium chloride injection with the mass concentration of 0.9%, and the sodium chloride injection is proper.
Further, the collagen is type I collagen. The method comprises the following specific steps: 6-12% of collagen.
Further, 3-5% of dimethylaminoethanol.
Further, PEG 6004-6%.
Further, it can be used for facial care.
Further, the injection is injected into the connective tissue or fascia layers of the face, and the injection is flattened by pressing with a hand, squeezed and spread toward the surrounding tissue, impacting away the adjacent local cortex.
The invention has the beneficial effects that:
1. the invention overcomes the problem of single effect of the traditional product, and the sodium hyaluronate is used for lubricating rough skin and preventing adhesion hyperplasia generated by tissue repair after liquid separation, avoids the risk that new tissues formed after trauma are likely to be hardened, and can tighten loose skin; the sodium chloride injection has the functions of diluting all components, and simultaneously assisting the separation of liquid in skin tissues; the collagen plays a role in nourishing skin, meanwhile, the dimethylaminoethanol plays a role in increasing the content of the collagen and relieving the wrinkle depth, the problem of facial skin aging is radically solved, and repeated injection is not needed.
2. The invention utilizes the hydrodynamic force soft stripping action of the nutrient injection to form wound under the skin, the human tissue can activate the strong self-repairing capability of the human body after being wounded to form an adhesive protein, namely the scar which is usually called by us has two characteristics, namely, the growing power and the contracture power. The hyperplastic force can form space occupation under the skin, and the place with wrinkles, depressions and incomplete congenital development of the skin is restored and plump; the contracture force can tighten the skin from all directions to the middle to form a compact collagen fiber net under the skin, so that the effect of tightening the skin without loosening and drooping is achieved, and the gravity is effectively resisted.
3. Hyaluronic acid with different molecular weights has different using effects, the cosmetic usage is generally not more than 150 thousands, and the nutrient injection of the invention has the best effect on the problems of deep wrinkles on the face and adhesion of tissue repair lacuna.
The nutrient injection has strong proliferation and tissue repair performance, and full, compact, smooth and beautiful youthful vigor appearance is achieved by utilizing the proliferation and the repair performance of the nutrient injection; meanwhile, the utility model has the characteristics of natural effect, convenient use and the like.
Drawings
Detailed Description
The invention provides an autologous repair nutrient injection and a using method thereof.
The invention provides an auto-repairing nutrient injection which comprises a sodium chloride solution, collagen, PEG600, dimethylaminoethanol and cationic hyaluronic acid.
Example 1
The formula is as follows: 6% of collagen, 4% of PEG 6004%, 4% of dimethylaminoethanol, 1% of sodium hyaluronate gel and a proper amount of sodium chloride solution.
Example 2
The formula is as follows: 6% of collagen, 4% of PEG 6004%, 4% of dimethylaminoethanol, 3% of sodium hyaluronate gel and a proper amount of sodium chloride solution.
Example 3
The formula is as follows: 12% of collagen, 4% of PEG 6004%, 4% of dimethylaminoethanol, 1% of sodium hyaluronate gel and a proper amount of sodium chloride solution.
Example 4
The formula is as follows: 12% of collagen, 4% of PEG 6004%, 4% of dimethylaminoethanol, 3% of sodium hyaluronate gel and a proper amount of sodium chloride solution.
The molecular weight of the sodium hyaluronate is 200 ten thousand daltons.
The sodium chloride solution is sodium chloride injection with the mass concentration of 0.9%.
Example 5
The application method of the nutrient injection for the facial skin self-repairing comprises the steps of injecting the nutrient injection into a connective tissue layer or a fascia layer, flattening the nutrient injection by pressing with hands, extruding the nutrient injection to spread to surrounding tissues, and separating adjacent local cortex by impact.
Performance testing of examples 1-4:
4 healthy volunteers were selected as test subjects. Each test subject was injected with the nutritional injection of examples 1-4 above, and the condition of the facial skin at the injection site 10 days after injection was visually observed. The results of the performance measurements are shown in Table 1.
Example 1 Example 1 Example 2 Example 3 Example 4
Wrinkling condition on injection 4.5±0.5 5.0±0.5 5.5±0.5 6.0±0.5
Wrinkle condition 10 days after injection 4.0±0.5 4.1±0.5 4.7±0.5 4.6±0.5
As can be seen from the data in the table 1, after the nutritional injection of the embodiments 1 to 4 is injected, wrinkles at the injection part are obviously reduced, which shows that the nutritional injection of the embodiments 1 to 4 can enable the skin to achieve a full, compact, smooth and beautiful youthful state, and has the characteristics of natural effect, convenient use and the like.
The present invention and its embodiments have been described above, but the description is not limitative, and the actual structure is not limited thereto. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (7)

1. An autologous repair nutrient injection, which is characterized in that: comprises sodium chloride solution, collagen, PEG600, dimethylaminoethanol and cationic hyaluronic acid.
2. The self-repairing nutrient injection according to claim 1, wherein: the cationic hyaluronic acid is sodium hyaluronate gel.
3. The self-repairing nutrient injection according to claim 2, wherein: the molecular weight of the sodium hyaluronate is 200 ten thousand daltons.
4. The self-repairing nutrient injection according to claim 1, wherein: the sodium chloride solution is sodium chloride injection with the mass concentration of 0.9%.
5. The self-repairing nutrient injection according to claim 1, wherein: the collagen is type I collagen.
6. The method for applying the self-repairing nutrient injection according to claim 1, wherein the self-repairing nutrient injection comprises the following steps: it can be used for caring facial skin.
7. The method for applying the self-repairing nutrient injection according to claim 6, wherein the self-repairing nutrient injection comprises the following steps: injecting the nutrient injection into the connective tissue layer or fascia layer of the face, pressing the nutrient injection with hands to flatten the nutrient injection, extruding the nutrient injection to diffuse to the surrounding tissues, and separating the adjacent local cortex by impact to form a wound.
CN202210196283.6A 2022-03-02 2022-03-02 Self-repairing nutrient injection and application method thereof Pending CN114558169A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210196283.6A CN114558169A (en) 2022-03-02 2022-03-02 Self-repairing nutrient injection and application method thereof

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Application Number Priority Date Filing Date Title
CN202210196283.6A CN114558169A (en) 2022-03-02 2022-03-02 Self-repairing nutrient injection and application method thereof

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CN114558169A true CN114558169A (en) 2022-05-31

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080274946A1 (en) * 2004-10-01 2008-11-06 Giampapa Vincent C Method and composition for restoration of age related tissue loss in the face or selected areas of the body
WO2014044808A2 (en) * 2012-09-21 2014-03-27 Labo Cosprophar Ag Fast-penetration cosmetic dermal filler for topical application
CN104922698A (en) * 2015-06-03 2015-09-23 广州暨南生物医药研究开发基地有限公司 Human stem cell growth factor injection and preparation method thereof
CN109528642A (en) * 2018-12-27 2019-03-29 上海欧邦医疗管理有限公司 A kind of autogenous repairing nutrient injection and its application method
CN111632070A (en) * 2020-06-18 2020-09-08 上海鄄飞健康管理咨询有限公司 Nutritional injection for neck skin repair and application method thereof
WO2021234074A1 (en) * 2020-05-20 2021-11-25 Monderna Health & Wellness Composition comprising different specific collagens and uses on the skin

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080274946A1 (en) * 2004-10-01 2008-11-06 Giampapa Vincent C Method and composition for restoration of age related tissue loss in the face or selected areas of the body
WO2014044808A2 (en) * 2012-09-21 2014-03-27 Labo Cosprophar Ag Fast-penetration cosmetic dermal filler for topical application
CN104922698A (en) * 2015-06-03 2015-09-23 广州暨南生物医药研究开发基地有限公司 Human stem cell growth factor injection and preparation method thereof
CN109528642A (en) * 2018-12-27 2019-03-29 上海欧邦医疗管理有限公司 A kind of autogenous repairing nutrient injection and its application method
WO2021234074A1 (en) * 2020-05-20 2021-11-25 Monderna Health & Wellness Composition comprising different specific collagens and uses on the skin
CN111632070A (en) * 2020-06-18 2020-09-08 上海鄄飞健康管理咨询有限公司 Nutritional injection for neck skin repair and application method thereof

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Application publication date: 20220531

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