CN114558169A - Self-repairing nutrient injection and application method thereof - Google Patents
Self-repairing nutrient injection and application method thereof Download PDFInfo
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- CN114558169A CN114558169A CN202210196283.6A CN202210196283A CN114558169A CN 114558169 A CN114558169 A CN 114558169A CN 202210196283 A CN202210196283 A CN 202210196283A CN 114558169 A CN114558169 A CN 114558169A
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- nutrient injection
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- 239000007924 injection Substances 0.000 title claims abstract description 46
- 238000002347 injection Methods 0.000 title claims abstract description 46
- 235000015097 nutrients Nutrition 0.000 title claims abstract description 29
- 238000000034 method Methods 0.000 title claims abstract description 12
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 22
- 102000008186 Collagen Human genes 0.000 claims abstract description 17
- 108010035532 Collagen Proteins 0.000 claims abstract description 17
- 229920001436 collagen Polymers 0.000 claims abstract description 17
- 239000011780 sodium chloride Substances 0.000 claims abstract description 11
- 239000000243 solution Substances 0.000 claims abstract description 11
- UEEJHVSXFDXPFK-UHFFFAOYSA-N N-dimethylaminoethanol Chemical compound CN(C)CCO UEEJHVSXFDXPFK-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229960002887 deanol Drugs 0.000 claims abstract description 10
- 230000008439 repair process Effects 0.000 claims abstract description 10
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 7
- 230000001815 facial effect Effects 0.000 claims abstract description 7
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 7
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 7
- 125000002091 cationic group Chemical group 0.000 claims abstract description 6
- 229920002582 Polyethylene Glycol 600 Polymers 0.000 claims abstract description 4
- 229920002385 Sodium hyaluronate Polymers 0.000 claims description 11
- 229940010747 sodium hyaluronate Drugs 0.000 claims description 11
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 11
- 210000001519 tissue Anatomy 0.000 claims description 6
- 239000008354 sodium chloride injection Substances 0.000 claims description 5
- 210000002808 connective tissue Anatomy 0.000 claims description 3
- 210000003195 fascia Anatomy 0.000 claims description 3
- 102000012422 Collagen Type I Human genes 0.000 claims description 2
- 108010022452 Collagen Type I Proteins 0.000 claims description 2
- 230000003796 beauty Effects 0.000 abstract description 12
- 230000032683 aging Effects 0.000 abstract description 3
- 239000003814 drug Substances 0.000 abstract description 2
- 238000007665 sagging Methods 0.000 abstract description 2
- 230000000694 effects Effects 0.000 description 8
- 239000002537 cosmetic Substances 0.000 description 6
- 230000037303 wrinkles Effects 0.000 description 6
- 229920001223 polyethylene glycol Polymers 0.000 description 5
- 241000282414 Homo sapiens Species 0.000 description 4
- 235000016709 nutrition Nutrition 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 230000017423 tissue regeneration Effects 0.000 description 3
- 206010062575 Muscle contracture Diseases 0.000 description 2
- 208000006111 contracture Diseases 0.000 description 2
- 206010020718 hyperplasia Diseases 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 230000035755 proliferation Effects 0.000 description 2
- 238000000926 separation method Methods 0.000 description 2
- 230000009759 skin aging Effects 0.000 description 2
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 241001484259 Lacuna Species 0.000 description 1
- 208000012287 Prolapse Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 201000010251 cutis laxa Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000002390 hyperplastic effect Effects 0.000 description 1
- 230000003116 impacting effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/025—Other specific inorganic materials not covered by A61L27/04 - A61L27/12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/34—Materials or treatment for tissue regeneration for soft tissue reconstruction
Abstract
The invention provides an autologous repair nutrient injection and an application method thereof, belonging to the technical field of beauty medicine. Comprises sodium chloride solution, collagen, PEG600, dimethylaminoethanol and cationic hyaluronic acid. The self-repairing nutrient injection and the application method thereof provided by the invention have the advantages of effectively tensioning the skin, preventing the skin from loosening and sagging, delaying aging, being safe and healthy, and simultaneously enabling the facial skin to achieve a full, compact, smooth and beautiful youthful vigor state.
Description
Technical Field
The invention provides an autologous repair nutrient injection and an application method thereof, belonging to the technical field of beauty medicine.
Background
Beauty is a life style, and the desire for beauty varies more and more. Although the aesthetic looks of people are constantly changing, the pursuit of beauty is not always changed, thereby creating the beauty industry. Ever since the existence of human beings, there has been beauty treatment. The beauty treatment is to beautify the appearance of people. With the development of society and the improvement of science and technology, the beauty treatment is continuously changed and improved from content to form. In the cosmetic field, anti-aging is one of its most important components. When people age, the change of appearance is reflected in the aspect of face, and there are three main manifestations: wrinkles, prolapse, collapse. That is, the skin of people is aged loose with age, so that it is necessary to beautify, maintain and repair the skin of the face in order to make the face less afraid of aging.
For beautifying and maintaining, various modes such as external smearing, oral taking, injection beautifying and the like exist. The market of cosmetics for external application is coming to the fifth generation, namely the age of biological cosmetics, after the four generations of evolution and development of minerals, mutton fat, pure plants and chemical synthetic products. The first five generations of cosmetic products are collagen. Meanwhile, beauty lovers also try to supplement a large amount of collagen through food, health care products and the like, such as eating pig trotters or taking collagen oral liquid. However, the effects of both external use and internal use are difficult to rapidly and obviously realize, and the injection beauty has the problems of not long-term effect of absorbable injection and repeated injection and the problem of potential safety hazard of the non-absorbable injection. For repair and beauty, the human body has certain regeneration and repair capacity after skin is wounded. For example, when the wound field is small or the injury is light, repair can occur through the natural healing process. Therefore, the cosmetic effect of delaying skin aging can be achieved by utilizing self-repairing.
Disclosure of Invention
The self-repairing nutrient injection and the application method thereof provided by the invention have the advantages of effectively tensioning the skin, preventing the skin from loosening and sagging, delaying aging, being safe and healthy, and simultaneously enabling the facial skin to achieve a full, compact, smooth and beautiful youthful vigor state.
The invention provides an autologous repair nutrition injection which comprises a sodium chloride solution, collagen, PEG600, dimethylaminoethanol and cationic hyaluronic acid.
Further, the cationic hyaluronic acid is sodium hyaluronate gel. The method specifically comprises the following steps: 1-3% of sodium hyaluronate gel.
Further, the molecular weight of the sodium hyaluronate is 200 ten thousand daltons.
Further, the sodium chloride solution is sodium chloride injection with the mass concentration of 0.9%, and the sodium chloride injection is proper.
Further, the collagen is type I collagen. The method comprises the following specific steps: 6-12% of collagen.
Further, 3-5% of dimethylaminoethanol.
Further, PEG 6004-6%.
Further, it can be used for facial care.
Further, the injection is injected into the connective tissue or fascia layers of the face, and the injection is flattened by pressing with a hand, squeezed and spread toward the surrounding tissue, impacting away the adjacent local cortex.
The invention has the beneficial effects that:
1. the invention overcomes the problem of single effect of the traditional product, and the sodium hyaluronate is used for lubricating rough skin and preventing adhesion hyperplasia generated by tissue repair after liquid separation, avoids the risk that new tissues formed after trauma are likely to be hardened, and can tighten loose skin; the sodium chloride injection has the functions of diluting all components, and simultaneously assisting the separation of liquid in skin tissues; the collagen plays a role in nourishing skin, meanwhile, the dimethylaminoethanol plays a role in increasing the content of the collagen and relieving the wrinkle depth, the problem of facial skin aging is radically solved, and repeated injection is not needed.
2. The invention utilizes the hydrodynamic force soft stripping action of the nutrient injection to form wound under the skin, the human tissue can activate the strong self-repairing capability of the human body after being wounded to form an adhesive protein, namely the scar which is usually called by us has two characteristics, namely, the growing power and the contracture power. The hyperplastic force can form space occupation under the skin, and the place with wrinkles, depressions and incomplete congenital development of the skin is restored and plump; the contracture force can tighten the skin from all directions to the middle to form a compact collagen fiber net under the skin, so that the effect of tightening the skin without loosening and drooping is achieved, and the gravity is effectively resisted.
3. Hyaluronic acid with different molecular weights has different using effects, the cosmetic usage is generally not more than 150 thousands, and the nutrient injection of the invention has the best effect on the problems of deep wrinkles on the face and adhesion of tissue repair lacuna.
The nutrient injection has strong proliferation and tissue repair performance, and full, compact, smooth and beautiful youthful vigor appearance is achieved by utilizing the proliferation and the repair performance of the nutrient injection; meanwhile, the utility model has the characteristics of natural effect, convenient use and the like.
Drawings
Detailed Description
The invention provides an autologous repair nutrient injection and a using method thereof.
The invention provides an auto-repairing nutrient injection which comprises a sodium chloride solution, collagen, PEG600, dimethylaminoethanol and cationic hyaluronic acid.
Example 1
The formula is as follows: 6% of collagen, 4% of PEG 6004%, 4% of dimethylaminoethanol, 1% of sodium hyaluronate gel and a proper amount of sodium chloride solution.
Example 2
The formula is as follows: 6% of collagen, 4% of PEG 6004%, 4% of dimethylaminoethanol, 3% of sodium hyaluronate gel and a proper amount of sodium chloride solution.
Example 3
The formula is as follows: 12% of collagen, 4% of PEG 6004%, 4% of dimethylaminoethanol, 1% of sodium hyaluronate gel and a proper amount of sodium chloride solution.
Example 4
The formula is as follows: 12% of collagen, 4% of PEG 6004%, 4% of dimethylaminoethanol, 3% of sodium hyaluronate gel and a proper amount of sodium chloride solution.
The molecular weight of the sodium hyaluronate is 200 ten thousand daltons.
The sodium chloride solution is sodium chloride injection with the mass concentration of 0.9%.
Example 5
The application method of the nutrient injection for the facial skin self-repairing comprises the steps of injecting the nutrient injection into a connective tissue layer or a fascia layer, flattening the nutrient injection by pressing with hands, extruding the nutrient injection to spread to surrounding tissues, and separating adjacent local cortex by impact.
Performance testing of examples 1-4:
4 healthy volunteers were selected as test subjects. Each test subject was injected with the nutritional injection of examples 1-4 above, and the condition of the facial skin at the injection site 10 days after injection was visually observed. The results of the performance measurements are shown in Table 1.
Example 1 | Example 1 | Example 2 | Example 3 | Example 4 |
Wrinkling condition on injection | 4.5±0.5 | 5.0±0.5 | 5.5±0.5 | 6.0±0.5 |
Wrinkle condition 10 days after injection | 4.0±0.5 | 4.1±0.5 | 4.7±0.5 | 4.6±0.5 |
As can be seen from the data in the table 1, after the nutritional injection of the embodiments 1 to 4 is injected, wrinkles at the injection part are obviously reduced, which shows that the nutritional injection of the embodiments 1 to 4 can enable the skin to achieve a full, compact, smooth and beautiful youthful state, and has the characteristics of natural effect, convenient use and the like.
The present invention and its embodiments have been described above, but the description is not limitative, and the actual structure is not limited thereto. In summary, those skilled in the art should appreciate that they can readily use the disclosed conception and specific embodiments as a basis for designing or modifying other structures for carrying out the same purposes of the present invention without departing from the spirit and scope of the invention as defined by the appended claims.
Claims (7)
1. An autologous repair nutrient injection, which is characterized in that: comprises sodium chloride solution, collagen, PEG600, dimethylaminoethanol and cationic hyaluronic acid.
2. The self-repairing nutrient injection according to claim 1, wherein: the cationic hyaluronic acid is sodium hyaluronate gel.
3. The self-repairing nutrient injection according to claim 2, wherein: the molecular weight of the sodium hyaluronate is 200 ten thousand daltons.
4. The self-repairing nutrient injection according to claim 1, wherein: the sodium chloride solution is sodium chloride injection with the mass concentration of 0.9%.
5. The self-repairing nutrient injection according to claim 1, wherein: the collagen is type I collagen.
6. The method for applying the self-repairing nutrient injection according to claim 1, wherein the self-repairing nutrient injection comprises the following steps: it can be used for caring facial skin.
7. The method for applying the self-repairing nutrient injection according to claim 6, wherein the self-repairing nutrient injection comprises the following steps: injecting the nutrient injection into the connective tissue layer or fascia layer of the face, pressing the nutrient injection with hands to flatten the nutrient injection, extruding the nutrient injection to diffuse to the surrounding tissues, and separating the adjacent local cortex by impact to form a wound.
Priority Applications (1)
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CN202210196283.6A CN114558169A (en) | 2022-03-02 | 2022-03-02 | Self-repairing nutrient injection and application method thereof |
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CN202210196283.6A CN114558169A (en) | 2022-03-02 | 2022-03-02 | Self-repairing nutrient injection and application method thereof |
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Family Applications (1)
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CN202210196283.6A Pending CN114558169A (en) | 2022-03-02 | 2022-03-02 | Self-repairing nutrient injection and application method thereof |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080274946A1 (en) * | 2004-10-01 | 2008-11-06 | Giampapa Vincent C | Method and composition for restoration of age related tissue loss in the face or selected areas of the body |
WO2014044808A2 (en) * | 2012-09-21 | 2014-03-27 | Labo Cosprophar Ag | Fast-penetration cosmetic dermal filler for topical application |
CN104922698A (en) * | 2015-06-03 | 2015-09-23 | 广州暨南生物医药研究开发基地有限公司 | Human stem cell growth factor injection and preparation method thereof |
CN109528642A (en) * | 2018-12-27 | 2019-03-29 | 上海欧邦医疗管理有限公司 | A kind of autogenous repairing nutrient injection and its application method |
CN111632070A (en) * | 2020-06-18 | 2020-09-08 | 上海鄄飞健康管理咨询有限公司 | Nutritional injection for neck skin repair and application method thereof |
WO2021234074A1 (en) * | 2020-05-20 | 2021-11-25 | Monderna Health & Wellness | Composition comprising different specific collagens and uses on the skin |
-
2022
- 2022-03-02 CN CN202210196283.6A patent/CN114558169A/en active Pending
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080274946A1 (en) * | 2004-10-01 | 2008-11-06 | Giampapa Vincent C | Method and composition for restoration of age related tissue loss in the face or selected areas of the body |
WO2014044808A2 (en) * | 2012-09-21 | 2014-03-27 | Labo Cosprophar Ag | Fast-penetration cosmetic dermal filler for topical application |
CN104922698A (en) * | 2015-06-03 | 2015-09-23 | 广州暨南生物医药研究开发基地有限公司 | Human stem cell growth factor injection and preparation method thereof |
CN109528642A (en) * | 2018-12-27 | 2019-03-29 | 上海欧邦医疗管理有限公司 | A kind of autogenous repairing nutrient injection and its application method |
WO2021234074A1 (en) * | 2020-05-20 | 2021-11-25 | Monderna Health & Wellness | Composition comprising different specific collagens and uses on the skin |
CN111632070A (en) * | 2020-06-18 | 2020-09-08 | 上海鄄飞健康管理咨询有限公司 | Nutritional injection for neck skin repair and application method thereof |
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