CN114522810A - High-stability cell centrifuge for gene detection - Google Patents
High-stability cell centrifuge for gene detection Download PDFInfo
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- CN114522810A CN114522810A CN202210432589.7A CN202210432589A CN114522810A CN 114522810 A CN114522810 A CN 114522810A CN 202210432589 A CN202210432589 A CN 202210432589A CN 114522810 A CN114522810 A CN 114522810A
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/10—Centrifuges combined with other apparatus, e.g. electrostatic separators; Sets or systems of several centrifuges
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
- B04B5/0414—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B9/00—Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
- B04B9/02—Electric motor drives
- B04B9/04—Direct drive
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
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Abstract
The invention discloses a high-stability cell centrifuge for gene detection, which relates to the technical field of gene detection and comprises a base, a first centrifugal turntable and a mounting assembly, wherein a servo motor is mounted above the middle part of the base, a rotating shaft is arranged on the upper side of the servo motor, the first centrifugal turntable is mounted on the outer side above the rotating shaft, a first protection frame is fixed on the outer side below the first centrifugal turntable, the first centrifugal turntable comprises a rotating plate, a test tube cavity, a fixing rod, a mounting groove, an outer frame and a groove, the inner side of the rotating plate is provided with the test tube cavity, and the outer side of the rotating plate is fixed with the fixing rod. This cell centrifuge of high stability for gene testing, the frame that is the concentric circles form and distributes has constituted circular shape centrifugation carousel wholly with changeing the board, is convenient for carry out centrifugal treatment through centrifugal force to the test tube of inboard, through settling the subassembly convenient to detach or changing the centrifugal storehouse subassembly of damage to centrifugal rotary drum and lower rotary drum cooperation are convenient for adapt to the not test tube of co-altitude.
Description
Technical Field
The invention relates to the technical field of gene detection, in particular to a high-stability cell centrifuge for gene detection.
Background
The gene detection is a technology for detecting DNA through blood, other body fluids or cells, and after the peripheral venous blood or other tissue cells of a detected person are taken and amplified, DNA molecular information in the cells of the detected person is detected through specific equipment. In the gene detection process, a cell centrifuge is needed to centrifuge cells, and the centrifuge is a machine for separating components in liquid and solid particles or a mixture of liquid and liquid by using centrifugal force.
The existing cell centrifuge is generally of a single-layer structure, the centrifugation efficiency is low, and in the using process, the damaged centrifugal drum part is inconvenient to disassemble and replace, so that the cell centrifuge with high stability for gene detection is provided.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides a high-stability cell centrifuge for gene detection, which solves the problems in the background technology.
In order to achieve the purpose, the invention is realized by the following technical scheme: a cell centrifuge with high stability for gene detection comprises a base, a first centrifugal turntable and a placement component, wherein a servo motor is installed above the middle of the base, a rotating shaft is arranged on the upper side of the servo motor, the first centrifugal turntable is installed on the outer side of the upper portion of the rotating shaft, a first protection frame is fixed on the outer side of the lower portion of the first centrifugal turntable, the first centrifugal turntable comprises a rotating plate, a tube testing cavity, a fixing rod, a placement groove, an outer frame and a groove, the tube testing cavity is arranged on the inner side of the rotating plate, the fixing rod is fixed on the outer side of the rotating plate, the outer frame is fixed on the outer side of the fixing rod, the placement groove is arranged between the fixing rods, the groove is arranged in the middle of the inner portion of the outer frame, the placement component is installed in the placement groove and comprises a placement plate, a connecting plate, a positioning bolt, a metal plate and a magnetic suction plate, the connecting plate is fixed on the outer side of the placement plate, and the both sides of connecting plate are fixed mutually with the recess through positioning bolt, one side that the mounting plate is close to the commentaries on classics board is fixed with the metal sheet, one side that the metal sheet is close to the mounting groove is fixed with the magnetic attraction board, the below of mounting plate is fixed with centrifugal storehouse subassembly, and centrifugal storehouse subassembly includes centrifugal rotary drum, rubber spring and rubber splint, inner wall one side of centrifugal rotary drum is fixed with rubber spring, and the inboard of rubber spring is fixed with rubber splint.
Further, the upper end of rotation axis is fixed with the connection pivot, connect the top outside of pivot and install the centrifugal carousel of second, and the below outside of the centrifugal carousel of second is fixed with the second protective frame.
Furthermore, a rotating structure is formed between the first centrifugal turntable and the first protective frame through the servo motor and between the rotating shaft and the base, and the internal structures of the first centrifugal turntable and the second centrifugal turntable are the same.
Furthermore, the rotating plate and the outer frame form an integrated structure through the fixing rod, the outer frame and the groove on the inner side of the outer frame are both in an annular structure, and the outer frame and the rotating plate are distributed in a concentric circle shape.
Furthermore, the shape of the placing plate is matched with that of the placing groove, the connecting plate on one side of the placing plate is connected with the groove in a clamping manner, and twelve groups of placing plates and placing grooves are symmetrically distributed around the central line of the rotating plate.
Further, the centrifugation storehouse subassembly still includes outer casing, sliding tray, sliding block, lower rotary drum and locking bolt, the below both sides of resettlement plate all are fixed with the outer casing, and the inboard of outer casing is provided with the sliding tray, the inside slidable mounting of sliding tray has the sliding block, and runs through between sliding block and the sliding tray and have the locking bolt, one side of sliding block is fixed with down the rotary drum, and down the rotary drum is located the below of centrifugation rotary drum.
Furthermore, the vertical central line of lower rotary drum and the vertical central line coincidence of centrifugal rotary drum, and the lower rotary drum passes through sliding block, sliding tray and outer casing sliding connection.
Further, the top both sides of base are fixed with the curb plate, and the top of curb plate is fixed with the roof, spacing subassembly is all installed to the outer wall both sides of first protection frame and second protection frame, and spacing subassembly includes ball groove, ball, goes up fixed block, ball slide, spacing slider, lower fixed block and spacing spout, the outer wall upside of first protection frame and second protection frame is fixed with the ball groove, and the inboard in ball groove is provided with the ball, the fixed block is installed to the inboard top of curb plate, and the inboard of going up the fixed block is provided with the ball slide, the outer wall downside of first protection frame and second protection frame is fixed with the spacing slider, the fixed block is installed down to the inboard below of curb plate, and the inboard of fixed block is provided with spacing spout down.
Furthermore, a first positioning assembly is installed below the second protective frame and comprises a first telescopic rod, a first pressing plate and a first flexible layer, the first pressing plate is fixed below the first telescopic rod, and the first flexible layer is connected to the lower side of the first pressing plate in an adhesive mode.
Further, a second positioning assembly is installed below the top plate and comprises a second telescopic rod, a lifting plate, a movable shaft, a second pressing plate and a second flexible layer, the lifting plate is fixed below the second telescopic rod, the movable shaft is arranged on the lower side of the lifting plate, the second pressing plate is installed below the movable shaft, and the lower side of the second pressing plate is connected with the second flexible layer in a gluing mode.
The invention provides a high-stability cell centrifuge for gene detection, which has the following beneficial effects:
this cell centrifuge of high stability for gene testing, the frame that is the concentric circles form and distributes has constituted circular shape centrifugation carousel wholly with changeing the board, is convenient for carry out centrifugal treatment through centrifugal force to the test tube of inboard, through settling the subassembly convenient to detach or changing the centrifugal storehouse subassembly of damage to centrifugal rotary drum and lower rotary drum cooperation are convenient for adapt to the not test tube of co-altitude.
1. The high-stability cell centrifuge for gene detection is provided with a first centrifugal turntable and a second centrifugal turntable, the first centrifugal turntable is convenient to drive to rotate through a servo motor and a rotating shaft, the rotating shaft is fixedly connected with a connecting rotating shaft, the second centrifugal turntable is convenient to drive to rotate through the connecting rotating shaft, the first centrifugal turntable and the second centrifugal turntable have the same internal structure and can form a double-layer centrifugal structure, so that test tubes arranged in the centrifugal structures at the upper side and the lower side can be conveniently centrifuged, small-sized cell test tubes can be conveniently arranged in a test tube cavity, twelve arranging grooves corresponding to twelve groups of arranging plates are reserved between an outer frame and the rotating plates and are used for installing the arranging assemblies and the centrifugal bin assemblies, so that large-sized cell test tubes can be conveniently arranged through the centrifugal bin assemblies, and the centrifugal treatment can be carried out on the test tubes with two different sizes, the functionality is better.
2. This gene detects cell centrifuge with high stability is provided with the arrangement subassembly, the identical inside of being convenient for set plate setting at the arrangement groove of the shape of arrangement plate and arrangement groove, the inside of embedding to the recess can be gone into to the connecting plate of arrangement plate one side, it is fixed to be convenient for realize the locking between connecting plate and the frame through positioning bolt, it makes the arrangement plate set up stably to inhale the connection through magnetism between arrangement plate one side metal sheet and the commentaries on classics board one side magnetism suction plate, thereby the arrangement plate is convenient for dismantle or change the centrifugal storehouse subassembly of damage through arrangement subassembly with centrifugal rotary drum fixed connection, need not to change whole first centrifugal carousel or the centrifugal carousel of second.
3. This gene detects cell centrifuge with high stability is provided with centrifugation storehouse subassembly, rubber splint pass through the inner wall elastic connection of rubber spring with the centrifugal rotary drum, make rubber splint can carry out flexible centre gripping to the inside test tube of centrifugal rotary drum, the upside of rubber splint is the entering of the opening column structure of slope be convenient for the test tube, the vertical central line coincidence of the vertical central line of lower rotary drum and centrifugal rotary drum makes down the rotary drum can carry out the bearing to the bottom of the inside test tube of centrifugal rotary drum, the position height of the inboard lower rotary drum of slide adjustment oversheath of being convenient for through the mutually supporting between sliding block and the sliding tray, so as to adapt to the test tube of different length, thereby be convenient for lock the fixed position that makes lower rotary drum to the sliding block through the locking bolt.
4. This gene detects cell centrifuge with high stability is provided with spacing subassembly, the ball slide is convenient for carry on spacingly to the rotatory orbit of ball, spacing spout is convenient for carry on spacingly to the rotatory orbit of spacing slider, consequently sliding fit between the ball slide through the ball of ball inslot portion and last fixed block, sliding fit between the spacing spout through spacing slider and lower fixed block, make first centrifugal turntable, first protection frame, the centrifugal turntable of second, the second protection frame is more steady at the rotatory in-process of centrifugation, thereby can improve the holistic stability of centrifugal device.
5. The high-stability cell centrifuge for gene detection is provided with a first positioning component and a second positioning component, the first telescopic rod below the second protective frame is convenient for lifting and adjusting the position height of the first pressure plate and the first flexible layer, the first pressure plate, the second protective frame and the first centrifugal turntable synchronously rotate, so that the first flexible layer can be attached to the upper side surface of the first centrifugal turntable to press and limit the first centrifugal turntable and the test tubes inside the first centrifugal turntable, the second telescopic rod is convenient for lifting and adjusting the position height of the lifting plate and the second pressing plate, the second pressing plate is rotatably connected with the lifting plate through the movable shaft so as to be matched with the rotation of a second centrifugal turntable below the second pressing plate, make the flexible layer of second can laminate mutually with the side of going up of second centrifugal turntable and carry out the pressfitting spacing to second centrifugal turntable and inside test tube to avoid the test tube to break away from by the upside in centrifugal treatment process.
Drawings
FIG. 1 is a schematic front view of a high stability cell centrifuge for gene detection according to the present invention;
FIG. 2 is an enlarged schematic view of the cell centrifuge of FIG. 1A for high stability in gene detection according to the present invention;
FIG. 3 is a schematic top view of a first centrifuge disk of a high stability cell centrifuge for gene detection according to the present invention;
FIG. 4 is a schematic diagram of an assembly structure of a first centrifugal turntable and a mounting assembly of a high-stability cell centrifuge for gene detection according to the present invention;
FIG. 5 is a schematic diagram showing an enlarged top view of a mounting assembly of a high stability cell centrifuge for gene detection according to the present invention;
FIG. 6 is a schematic view of the front view of the inner cross-sectional structure of the centrifuge chamber assembly of the high stability cell centrifuge for gene detection according to the present invention;
FIG. 7 is an enlarged schematic view of the cell centrifuge at B in FIG. 6, showing high stability for gene detection according to the present invention.
In the figure: 1. a base; 2. a servo motor; 3. a rotating shaft; 4. a first centrifugal turntable; 401. rotating the plate; 402. a tube testing cavity; 403. fixing the rod; 404. a placing groove; 405. an outer frame; 406. a groove; 5. a first protection frame; 6. connecting the rotating shaft; 7. a second centrifugal turntable; 8. a second protective frame; 9. arranging the component; 901. placing a plate; 902. a connecting plate; 903. positioning the bolt; 904. a metal plate; 905. a magnetic attraction plate; 10. a centrifugal bin assembly; 1001. a centrifugal drum; 1002. a rubber spring; 1003. a rubber splint; 1004. an outer shroud; 1005. a sliding groove; 1006. a slider; 1007. a lower drum; 1008. locking the bolt; 11. a side plate; 12. a top plate; 13. a limiting component; 1301. a ball groove; 1302. a ball bearing; 1303. an upper fixed block; 1304. a ball ramp; 1305. a limiting slide block; 1306. a lower fixed block; 1307. a limiting chute; 14. a first positioning assembly; 1401. a first telescopic rod; 1402. a first platen; 1403. a first flexible layer; 15. a second positioning assembly; 1501. a second telescopic rod; 1502. a lifting plate; 1503. a movable shaft; 1504. a second platen; 1505. a second flexible layer.
Detailed Description
Referring to fig. 1 to 7, the present invention provides a technical solution: a high-stability cell centrifuge for gene detection comprises a base 1, a first centrifugal turntable 4 and a placement component 9, wherein a servo motor 2 is installed above the middle of the base 1, a rotating shaft 3 is arranged on the upper side of the servo motor 2, the first centrifugal turntable 4 is installed on the outer side above the rotating shaft 3, a first protection frame 5 is fixed on the outer side below the first centrifugal turntable 4, the first centrifugal turntable 4 comprises a rotating plate 401, a test tube cavity 402, a fixing rod 403, a placement groove 404, an outer frame 405 and a groove 406, the inner side of the rotating plate 401 is provided with the test tube cavity 402, the outer side of the rotating plate 401 is fixed with the fixing rod 403, the outer frame 405 is fixed on the outer side of the fixing rod 403, the placement groove 404 is arranged between the fixing rods, the groove 406 is arranged in the middle of the outer frame 405, the placement component 9 is installed in the placement groove 404, and the placement component 9 comprises a placement plate 901, a connecting plate 902, a connecting plate 403 and a groove 406, Positioning bolt 903, metal sheet 904 and magnetism board 905 are inhaled, the outside of mounting plate 901 is fixed with connecting plate 902, and the both sides of connecting plate 902 are fixed mutually with recess 406 through positioning bolt 903, one side that mounting plate 901 is close to commentaries on classics board 401 is fixed with metal sheet 904, one side that metal sheet 904 is close to mounting groove 404 is fixed with magnetism board 905, the below of mounting plate 901 is fixed with centrifugal storehouse subassembly 10, and centrifugal storehouse subassembly 10 includes centrifugal rotary drum 1001, rubber spring 1002 and rubber splint 1003, the inner wall one side of centrifugal rotary drum 1001 is fixed with rubber spring 1002, and the inboard of rubber spring 1002 is fixed with rubber splint 1003.
Referring to fig. 1, a connecting shaft 6 is fixed at the upper end of the rotating shaft 3, a second centrifugal turntable 7 is installed on the outer side above the connecting shaft 6, and a second protective frame 8 is fixed on the outer side below the second centrifugal turntable 7; the first centrifugal turntable 4 and the first protective frame 5 form a rotating structure through the servo motor 2 and the rotating shaft 3 with the base 1, and the internal structures of the first centrifugal turntable 4 and the second centrifugal turntable 7 are the same;
the operation is as follows specifically, be convenient for drive the rotation of first centrifugal turntable 4 through servo motor 2 and rotation axis 3, rotation axis 3 with be connected pivot 6 fixed connection, be convenient for drive the rotation of second centrifugal turntable 7 through connecting pivot 6, first centrifugal turntable 4 can make first centrifugal turntable 4 and second centrifugal turntable 7 constitute double-deck centrifugal structure with the inner structure of second centrifugal turntable 7 the same to be convenient for carry out centrifugal operation to the inside test tube that sets up of upper and lower both sides centrifugal structure.
Referring to fig. 4-5, the rotating plate 401 and the outer frame 405 form an integrated structure through the fixing rods 403, the outer frame 405 and the grooves 406 inside the outer frame are both in a ring-shaped structure, and the outer frame 405 and the rotating plate 401 are distributed in a concentric circle;
Referring to fig. 4, the shape of the mounting plate 901 is matched with that of the mounting groove 404, the connecting plate 902 on one side of the mounting plate 901 is connected with the groove 406 in a clamping manner, and twelve groups of the mounting plate 901 and the mounting groove 404 are symmetrically distributed about the center line of the rotating plate 401;
the shape of the placing plate 901 is matched with that of the placing groove 404, so that the placing plate 901 is arranged in the placing groove 404, the connecting plate 902 on one side of the placing plate 901 can be clamped into the groove 406, the connecting plate 902 and the outer frame 405 are locked and fixed conveniently through the positioning bolt 903, the placing plate 901 is stably arranged through the magnetic attraction connection between the metal plate 904 on one side of the placing plate 901 and the magnetic attraction plate 905 on one side of the rotating plate 401, the placing plate 901 is fixedly connected with the centrifugal rotating drum 1001, so that the damaged centrifugal bin assembly 10 can be conveniently detached or replaced through the placing assembly 9, and the whole first centrifugal rotating disc 4 or the whole second centrifugal rotating disc 7 does not need to be replaced.
Referring to fig. 5-7, the centrifugal bin assembly 10 further includes an outer casing 1004, a sliding groove 1005, a sliding block 1006, a lower rotating cylinder 1007 and a locking bolt 1008, wherein the outer casing 1004 is fixed on both sides below the placement plate 901, the sliding groove 1005 is formed in the inner side of the outer casing 1004, the sliding block 1006 is slidably installed in the sliding groove 1005, the locking bolt 1008 penetrates through the sliding groove 1005 between the sliding block 1006 and the sliding groove 1005, the lower rotating cylinder 1007 is fixed on one side of the sliding block 1006, and the lower rotating cylinder 1007 is located below the centrifugal rotating cylinder 1001; the vertical center line of the lower rotary cylinder 1007 is superposed with the vertical center line of the centrifugal rotary cylinder 1001, and the lower rotary cylinder 1007 is connected with the outer guard 1004 in a sliding way through a sliding block 1006 and a sliding groove 1005;
the concrete operation is as follows, rubber splint 1003 passes through the inner wall elastic connection of rubber spring 1002 with centrifugal rotary drum 1001, make rubber splint 1003 can carry out flexible centre gripping to the inside test tube of centrifugal rotary drum 1001, the upside of rubber splint 1003 is the entering of the opening column structure of slope convenient to test tube, the vertical central line of down section of thick bamboo 1007 makes down section of thick bamboo 1007 can carry out the bearing to the bottom of the inside test tube of centrifugal rotary drum 1001 with the vertical central line coincidence of centrifugal rotary drum 1001, the position height of the inboard lower section of thick bamboo 1007 of slide adjustment oversheath of being convenient for through the mutually supporting between sliding block 1006 and the sliding tray 1005, so that adapt to the test tube of different length, thereby be convenient for lock the fixed position that makes down section of thick bamboo 1007 to sliding block 1006 through locking bolt 1008.
Referring to fig. 1, side plates 11 are fixed on two sides of the upper portion of a base 1, a top plate 12 is fixed on the upper portion of each side plate 11, limiting assemblies 13 are mounted on two sides of the outer walls of a first protective frame 5 and a second protective frame 8, each limiting assembly 13 comprises a ball groove 1301, balls 1302, an upper fixing block 1303, a ball slideway 1304, a limiting slider 1305, a lower fixing block 1306 and a limiting chute 1307, the ball grooves 1301 are fixed on the upper sides of the outer walls of the first protective frame 5 and the second protective frame 8, the balls 1302 are arranged on the inner sides of the ball grooves 1301, the upper fixing block 1303 is mounted on the upper side of the inner side of each side plate 11, the ball slideway 1304 is arranged on the inner side of the upper fixing block 1303, the limiting slider 1305 is fixed on the lower sides of the outer walls of the first protective frame 5 and the second protective frame 8, the lower fixing block 1306 is mounted on the lower side of the inner side of each side plate 11, and the limiting chute 1307 is arranged on the inner side of the lower fixing block 1306;
the operation is as follows, the ball slideway 1304 is convenient for limiting the rotating movement track of the ball 1302, the limiting sliding groove 1307 is convenient for limiting the rotating movement track of the limiting sliding block 1305, and therefore the sliding fit between the ball 1302 inside the ball groove 1301 and the ball slideway 1304 of the upper fixing block 1303 and the sliding fit between the limiting sliding block 1305 and the limiting sliding groove 1307 of the lower fixing block 1306 are achieved, so that the first centrifugal turntable 4, the first protection frame 5, the second centrifugal turntable 7 and the second protection frame 8 are more stable in the centrifugal rotating process, and the overall stability of the centrifugal device can be improved.
Referring to fig. 1, a first positioning assembly 14 is installed below the second protective frame 8, the first positioning assembly 14 includes a first telescopic rod 1401, a first pressing plate 1402 and a first flexible layer 1403, the first pressing plate 1402 is fixed below the first telescopic rod 1401, and the first flexible layer 1403 is glued to the lower side of the first pressing plate 1402;
the operation is as follows specifically, the first telescopic link 1401 through 8 belows in the second protection frame is convenient for go up and down to adjust the position height of first clamp plate 1402 and first flexible layer 1403, first clamp plate 1402, second protection frame 8 and first centrifugal carousel 4 synchronous revolution for first flexible layer 1403 of first clamp plate 1402 downside can laminate mutually with the last side of first centrifugal carousel 4 and carry out the pressfitting spacingly to first centrifugal carousel 4 and inside test tube, avoid the test tube to break away from first centrifugal carousel 4 by the upside in the centrifugal processing process.
A second positioning assembly 15 is mounted below the top plate 12, the second positioning assembly 15 comprises a second telescopic rod 1501, a lifting plate 1502, a movable shaft 1503, a second pressing plate 1504 and a second flexible layer 1505, the lifting plate 1502 is fixed below the second telescopic rod 1501, the movable shaft 1503 is arranged on the lower side of the lifting plate 1502, the second pressing plate 1504 is mounted below the movable shaft 1503, and the second flexible layer 1505 is glued to the lower side of the second pressing plate 1504;
the operation is as follows specifically, be convenient for through second telescopic link 1501 to go up and down to adjust the position height of lifter plate 1502 and second clamp plate 1504, second clamp plate 1504 rotates with lifter plate 1502 through loose axle 1503 to be connected and is convenient for cooperate the rotation of below second centrifugal turntable 7 for second flexible layer 1505 of second clamp plate 1504 downside can laminate mutually with the last side of second centrifugal turntable 7 and carry out the pressfitting spacing to second centrifugal turntable 7 and inside test tube, avoid the test tube to break away from first centrifugal turntable 4 by the upside in the centrifugation process.
To sum up, when the high-stability cell centrifuge for gene detection is used, the placing plate 901 can be arranged inside the placing groove 404, so that the connecting plate 902 on one side of the placing plate 901 can be clamped and embedded into the groove 406, then the connecting plate 902 and the outer frame 405 are locked and fixed through the positioning bolt 903, meanwhile, the placing plate 901 is stably arranged through the magnetic attraction connection between the metal plate 904 on one side of the placing plate 901 and the magnetic attraction plate 905 on one side of the rotating plate 401, and otherwise, the damaged centrifugal bin assembly 10 can be detached or replaced through the placing assembly 9 when the centrifugal rotating drum is damaged, and the whole first centrifugal rotating disc 4 or the second centrifugal rotating disc 7 does not need to be replaced;
then the test tube can be placed in the test tube cavity 402 of the rotating plate 401 or in the centrifugal drum 1001, at this time, the upper side of the rubber clamp plate 1003 is of an inclined opening-shaped structure so as to facilitate the entry of the test tube, the rubber clamp plate 1003 can flexibly clamp the test tube in the centrifugal drum 1001 under the elastic action of the rubber spring 1002, then the position height of the lower drum 1007 inside the outer protecting plate 1004 can be adjusted through the mutual matching between the sliding block 1006 and the sliding groove 1005 in a sliding manner, and the sliding block 1006 is locked and fixed through the locking bolt 1008 so as to fix the position of the lower drum 1007, so that the lower drum 1007 supports the bottom of the test tube in the centrifugal drum 1001;
then, the first telescopic rod 1401 below the second protective frame 8 is used for lifting and lowering to adjust the position heights of the first pressing plate 1402 and the first flexible layer 1403, the first pressing plate 1402, the second protective frame 8 and the first centrifugal turntable 4 rotate synchronously, so that the first flexible layer 1403 can be attached to the upper side surface of the first centrifugal turntable 4 to press and limit the first centrifugal turntable 4 and test tubes inside the first centrifugal turntable 4, the second telescopic rod 1501 is used for lifting and lowering to adjust the position heights of the lifting plate 1502 and the second pressing plate 1504, the second pressing plate 1504 can be matched with the rotation of the second centrifugal turntable 7 below due to the rotary connection of the second pressing plate 1504 and the lifting plate 1502 through the movable shaft 1503, the second flexible layer 1505 can be attached to the upper side surface of the second centrifugal turntable 7 to press and limit the second centrifugal turntable 7 and test tubes inside the second centrifugal turntable 7, and the test tubes are prevented from being separated in the centrifugal processing process;
then the servo motor 2 and the rotating shaft 3 drive the first centrifugal turntable 4 to rotate, the rotating shaft 3 is fixedly connected with the connecting rotating shaft 6, so that the second centrifugal turntable 7 can be synchronously driven to rotate through the connecting rotating shaft 6, the first centrifugal turntable 4 and the second centrifugal turntable 7 can form a double-layer centrifugal structure due to the fact that the internal structures of the first centrifugal turntable 4 and the second centrifugal turntable 7 are the same, and therefore centrifugal operation can be conducted on test tubes arranged inside the centrifugal structures on the upper side and the lower side, in the process, balls 1302 inside ball grooves 1301 on the upper side of the outer walls of the first protection frame 5 and the second protection frame 8 can roll inside ball slide ways 1304 of the upper fixing block 1303, and limiting slide blocks on the lower side of the outer walls of the first protection frame 5 and the second protection frame 8 can slide inside limiting slide grooves 1307 of the lower fixing block 1306, so that the first centrifugal turntable 4, the first protection frame 5, the second protection frame 1305, The second centrifugal turntable 7 and the second protective frame 8 are more stable in the centrifugal rotation process, so that the use process of the high-stability cell centrifuge for the whole gene detection is completed.
Claims (10)
1. The high-stability cell centrifuge for gene detection is characterized by comprising a base (1), a first centrifugal turntable (4) and a placement assembly (9), wherein a servo motor (2) is installed above the middle of the base (1), a rotating shaft (3) is arranged on the upper side of the servo motor (2), the first centrifugal turntable (4) is installed on the outer side above the rotating shaft (3), a first protection frame (5) is fixed on the outer side below the first centrifugal turntable (4), the first centrifugal turntable (4) comprises a rotating plate (401), a test tube cavity (402), a fixing rod (403), a placement groove (404), an outer frame (405) and a groove (406), the inner side of the rotating plate (401) is provided with the test tube cavity (402), the outer side of the rotating plate (401) is fixed with the fixing rod (403), and the outer frame (405) is fixed on the outer side of the fixing rod (403), and a mounting groove (404) is arranged between the fixing rods (403), a groove (406) is arranged in the middle of the inner part of the outer frame (405), the mounting component (9) is mounted in the mounting groove (404), the mounting component (9) comprises a mounting plate (901), a connecting plate (902), a positioning bolt (903), a metal plate (904) and a magnetic attraction plate (905), the connecting plate (902) is fixed to the outer side of the mounting plate (901), two sides of the connecting plate (902) are fixed with the groove (406) through the positioning bolt (903), the metal plate (904) is fixed to one side of the mounting plate (901) close to the rotating plate (401), the magnetic attraction plate (905) is fixed to one side of the metal plate (904) close to the mounting groove (404), a centrifugal bin component (10) is fixed to the lower part of the mounting plate (901), and the centrifugal bin component (10) comprises a centrifugal rotating drum (1001), The centrifugal drum comprises a rubber spring (1002) and a rubber clamping plate (1003), wherein the rubber spring (1002) is fixed on one side of the inner wall of the centrifugal drum (1001), and the rubber clamping plate (1003) is fixed on the inner side of the rubber spring (1002).
2. The cytospin with high stability for gene detection according to claim 1, wherein a connection shaft (6) is fixed on the upper end of the rotation shaft (3), a second centrifugal turntable (7) is installed on the outer side above the connection shaft (6), and a second protection frame (8) is fixed on the outer side below the second centrifugal turntable (7).
3. The cytospin machine with high stability for gene detection according to claim 2, wherein the first centrifugal turntable (4) and the first protection frame (5) form a rotating structure with the base (1) through the servo motor (2), the rotating shaft (3), and the inner structure of the first centrifugal turntable (4) is the same as that of the second centrifugal turntable (7).
4. The cytospin machine with high stability for gene detection according to claim 1, wherein the rotating plate (401) is integrated with the outer frame (405) through the fixing rod (403), the outer frame (405) and the inner groove (406) are both in a ring structure, and the outer frame (405) and the rotating plate (401) are distributed in a concentric circle.
5. The cytospin with high stability for gene detection according to claim 1, wherein the shape of the installation plate (901) is matched with that of the installation groove (404), the connection plate (902) at one side of the installation plate (901) is connected with the groove (406) in a clamping manner, and twelve groups of installation plates (901) and installation grooves (404) are symmetrically distributed about the center line of the rotating plate (401).
6. The cytospin with high stability for gene detection according to claim 1, wherein the centrifugation bin assembly (10) further comprises an outer protection plate (1004), a sliding groove (1005), a sliding block (1006), a lower rotating cylinder (1007) and a locking bolt (1008), the outer protection plate (1004) is fixed on both sides of the lower portion of the placement plate (901), the sliding groove (1005) is arranged on the inner side of the outer protection plate (1004), the sliding block (1006) is slidably mounted inside the sliding groove (1005), the locking bolt (1008) penetrates through the sliding groove (1005) and the sliding block (1006), the lower rotating cylinder (1007) is fixed on one side of the sliding block (1006), and the lower rotating cylinder (1007) is located below the centrifugation rotating cylinder (1001).
7. The cytospin with high stability for gene detection according to claim 6, wherein the vertical center line of the lower rotating cylinder (1007) coincides with the vertical center line of the centrifugal rotating cylinder (1001), and the lower rotating cylinder (1007) is slidably connected with the outer guard (1004) through a slide block (1006) and a slide groove (1005).
8. The cytospin with high stability for gene detection according to claim 1, wherein side plates (11) are fixed on both sides of the upper part of the base (1), a top plate (12) is fixed on the upper part of the side plates (11), limiting assemblies (13) are installed on both sides of the outer walls of the first protective frame (5) and the second protective frame (8), each limiting assembly (13) comprises a ball groove (1301), a ball (1302), an upper fixing block (1303), a ball slideway (1304), a limiting slider (1305), a lower fixing block (1306) and a limiting slideway (1307), the ball grooves (1301) are fixed on the upper sides of the outer walls of the first protective frame (5) and the second protective frame (8), the balls (1302) are arranged on the inner sides of the ball grooves (1301), the upper fixing block (1303) is installed on the upper side of the side plate (11), and the ball slideway (1304) is arranged on the inner side of the upper fixing block (1303), and limiting sliding blocks (1305) are fixed on the lower sides of the outer walls of the first protective frame (5) and the second protective frame (8), lower fixing blocks (1306) are installed below the inner sides of the side plates (11), and limiting sliding grooves (1307) are formed in the inner sides of the lower fixing blocks (1306).
9. The cytospin with high stability for gene detection according to claim 2, wherein a first positioning component (14) is installed below the second protective frame (8), the first positioning component (14) comprises a first telescopic rod (1401), a first pressing plate (1402) and a first flexible layer (1403), the first pressing plate (1402) is fixed below the first telescopic rod (1401), and the first flexible layer (1403) is glued to the lower side of the first pressing plate (1402).
10. The cytospin with high stability for gene detection according to claim 8, wherein a second positioning assembly (15) is installed below the top plate (12), the second positioning assembly (15) comprises a second telescopic rod (1501), a lifting plate (1502), a movable shaft (1503), a second pressing plate (1504) and a second flexible layer (1505), the lifting plate (1502) is fixed below the second telescopic rod (1501), the movable shaft (1503) is arranged on the lower side of the lifting plate (1502), the second pressing plate (1504) is installed below the movable shaft (1503), and the second flexible layer (1505) is glued to the lower side of the second pressing plate (1504).
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| CN114522810B (en) | 2022-08-16 |
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