CN114515733A - Hair washing device of solid-phase microporous reactor and using method - Google Patents

Hair washing device of solid-phase microporous reactor and using method Download PDF

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Publication number
CN114515733A
CN114515733A CN202210111287.XA CN202210111287A CN114515733A CN 114515733 A CN114515733 A CN 114515733A CN 202210111287 A CN202210111287 A CN 202210111287A CN 114515733 A CN114515733 A CN 114515733A
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cavity
liquid
micropore
washing
waste liquid
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CN114515733B (en
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徐高扬
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Xiamen Xianming Biotechnology Co ltd
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Xiamen Xianming Biotechnology Co ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B9/00Cleaning hollow articles by methods or apparatus specially adapted thereto 
    • B08B9/08Cleaning containers, e.g. tanks
    • B08B9/093Cleaning containers, e.g. tanks by the force of jets or sprays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E60/00Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
    • Y02E60/10Energy storage using batteries

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Cleaning And Drying Hair (AREA)

Abstract

The invention discloses a hair washing device of a solid-phase microporous reactor and a using method, comprising the following steps: the top of the solid phase micropore is provided with an opening, and the bottom surface of the micropore cavity is provided with a gain structure; the hair washing liquid injection structure extends into the micropore cavity and keeps a certain distance with the inner side wall of the micropore cavity to form a liquid washing cavity; waste liquid suction and discharge structure, waste liquid suction and discharge structure includes that one is located the waste liquid derivation chamber in the flushing area that micropore vestibule and lotion chamber formed, the lateral wall axial connection that the waste liquid derivation chamber visited into the micropore vestibule has an extension edge, the shape of the shape adaptation gain structure on extension edge, it removes to the solid phase micropore in to combine together back removal with waste liquid suction and discharge structure to annotate the liquid structure with washing head, can erode in step, the suction action or go on in turn fast, can accomplish fast in the short time and erode the action with the suction, compare in current intermittent type nature take out, the washing mode that two steps of liquid feeding go on in turn, the abluent time has been shortened, the efficiency and the effect of work have been improved.

Description

Hair washing device of solid-phase microporous reactor and using method
Technical Field
The invention relates to a microporous hair washing device, in particular to a hair washing device of a solid-phase microporous reactor and a using method.
Background
Enzyme-linked immunoassay based on solid-phase micropores and tubes is applied to the fields of biological science research and clinical diagnosis for nearly half a century, and some emerging technology platforms are also realized based on the solid-phase micropores and the tubes.
In the manufacturing and detection processes of the labeled immunoassay reagent of the solid phase micropore and the solid phase tube, the cleaning process of the solid phase micropore and the solid phase tube is a very important operation step. Therefore, free components which do not participate in the reaction are fully separated and thoroughly washed, so that the free components which interfere with the detection are eliminated, the background is reduced to the minimum level, and the sensitivity of the detection method is ensured. The desired washing results are the most thorough washing, the least washing liquor remaining and the least time consuming. The existing instrument and equipment have a series of problems of complex structure, long washing time, residual washing liquid and the like.
So far, the washing modes aiming at the enzyme-linked immunoassay solid phase micropore and tube are as follows: 1. the straight-tube type long and short double needles are parallel and parallel, the long needle absorbs liquid, the short needle adds liquid, when in work, the hair is washed and slowly falls into the micropores, reaction liquid (the long needle) is firstly pumped, then the hair is lifted, the liquid injection needle is kept stand for a plurality of seconds after filling washing liquid, then the hair is fallen to pump waste liquid, and the steps are alternated for 4 to 5 times; 2. the straight cylinder type concentric circle sleeve needle, the outer ring needle is used for injecting liquid and the inner core needle is used for drawing liquid, and the liquid injection needle and the tail end of the liquid drawing needle are parallel and level or the middle liquid drawing needle is slightly longer. When the washing machine works, the washing head falls to the liquid level of the micropores, and the inner core liquid pumping needle pumps and exhausts waste liquid; then the hair is lifted, the liquid injection needle (outer ring) is injected with the washing liquid, the mixture is kept stand for a plurality of seconds, and then the mixture falls to the liquid level of the micropore by the washing device and the inner core liquid extraction needle is used for pumping and discharging the waste liquid, and the steps are alternated for a plurality of times. The two washing modes have complicated structure and take much time, and residual washing liquor exists.
The liquid injection needles and the liquid suction needles are all in a thin-circumference straight-cylinder structure, the inner diameter of the inner diameter needle of the liquid suction needle is much smaller than that of the micropore, and the suction force on the attachments on the reaction interface of the circumference wall is weak; the liquid pumping sequence is that the liquid is pumped from top to bottom in a contact surface type layered way, the suction force to the reaction interface at the bottom and the side wall of the micropore is weak, and the washing is insufficient; the filling, standing and liquid extraction are basic operation procedures and requirements, and much time is consumed; the waste liquid is sucked and discharged in two steps in the micropores through software, so that the washing time is prolonged, and the washing efficiency is reduced; the liquid adding amount is controlled, and suction is ensured to be extremely little residual; the filling and drawing of the solution are not particularly concerned with the reaction interface, and are time-consuming, inefficient and prone to failure in conventional solid phase microwells, tube reagent production, automated production of assays, assay analytical instruments. The defects of the traditional automatic washing device restrict and prevent the value exertion of the product of enzyme-linked immunoassay based on solid-phase micropores and tubes to a certain extent.
Disclosure of Invention
The invention provides a hair washing device of a solid-phase microporous reactor and a using method thereof, which can effectively solve the problems.
The invention is realized by the following steps:
a solid phase micro-porous reactor hair washing device comprising:
the solid-phase micropore with an opening at the top comprises a micropore cavity, the top of the micropore cavity is provided with a pore edge, and the bottom of the micropore cavity is provided with a gain structure;
the washing liquid injection structure comprises a washing liquid cavity which is deep into the micropore cavity and is arranged at an interval with the inner side wall of the micropore cavity, the outer peripheral surface of the washing liquid cavity extends outwards to form a platform edge which is erected at the top of the hole edge, the two axial ends of the washing liquid cavity are respectively provided with an upper opening and a lower opening, and the top of the washing liquid cavity is provided with a liquid injection pipe which is externally connected with an external liquid injection structure through a washing liquid injection pipe nut;
the waste liquid suction and discharge structure vertically penetrates through the upper opening and the lower opening of the washing liquid cavity, the waste liquid suction and discharge structure comprises a waste liquid leading-out cavity located in a washing area formed by the micropore cavity and the washing liquid cavity, the side wall of the waste liquid leading-out cavity extending into the micropore cavity is axially connected with an extension edge, the shape of the extension edge is matched with that of the gain structure, and the extension edge keeps a distance of not more than 1mm from the bottom of the micropore cavity and the inner side wall, so that washing liquid on the bottom of the micropore cavity and the surface of the inner side wall can be fully washed when flowing.
Establish including the lid further the liquid pipe nut is annotated to shampoo chamber keeps away from the shampoo of solid phase micropore one side, the liquid pipe nut cover is annotated to the shampoo is established the top of liquid structure, waste liquid suction structure is annotated to the shampoo and a constitution airtight space, set up the confession on the liquid pipe nut is annotated to the shampoo the waste liquid derives the round hole that the chamber passes through and supplies the through-hole that the notes liquid pipe passes through.
As a further improvement, one side of the platform edge, which is close to the solid phase micropores, is provided with a groove, and the groove of the platform edge is matched with the hole edge of the solid phase micropores.
As a further improvement, the bottom of the washing liquid cavity is an inclined angle pointing to the micropore cavity, and an inclined cutting plane of the inclined angle faces to the waste liquid suction and discharge structure.
As a further improvement, the outer wall of the waste liquid suction and discharge structure is fixed on the inner wall of the liquid injection structure of the shampoo through a connecting piece.
As a further improvement, when the waste liquid suction and discharge structure is matched with the solid phase micropores, the extension edge is always parallel to the surface of the gain structure.
As a further improvement, the distance between the epitaxial edge and the gain structure is less than 1mm, and the distance between the epitaxial edge and the inner side wall of the micropore cavity is less than 1 mm.
As a further improvement, the shape of the gain structure is a plane, a rotating body, or a rotating body with a notch.
As a further improvement, the height of the epitaxial rim increases or decreases with the shape change of the gain structure.
The use method of the solid-phase microporous reactor hair washing device comprises the following steps:
s1; a washing liquid filling liquid path and a waste liquid pumping and discharging liquid path are respectively connected with the through hole of the liquid injection pipe and the round hole of the waste liquid guide cavity to form a washing liquid flow path and a pumping and discharging flow path;
s2; starting the liquid pumping power of the waste liquid pumping and discharging liquid path, embedding the extension edge on the waste liquid guide cavity into the micropore cavity, simultaneously clamping the hole edge of the micropore cavity into the groove of the platform edge, embedding the washing liquid cavity into the inner wall of the micropore cavity, extruding the substances to be pumped in the micropore cavity to the side wall and the bottom of the extension edge in the clamping process, and completing pumping of unreacted substances or waste liquid;
s3; starting the liquid injection power of the washing liquid filling liquid path, introducing the washing liquid into the washing liquid cavity through the washing liquid flow path, flowing into the washing area along the inclined surface, and washing the inner side wall of the micropore cavity and the bottom gain structure;
s4; after the washing is finished, the washing liquid is discharged from the waste liquid guide cavity through gaps among the outer edge of the extension edge, the inner side wall of the micropore cavity and the bottom gain structure, and the liquid can be alternately pumped and the washing liquid can be simultaneously carried out.
The invention has the beneficial effects that:
when the waste liquid suction and discharge structure is matched with the solid-phase micropores, the extension edge of the waste liquid suction and discharge structure can extrude the waste liquid and the washing liquid to the side wall and the bottom of the micropore cavity, so that an interface scouring effect can be generated on the side wall and the bottom of the micropore cavity, all unreacted components are washed away, and compared with the conventional single-thin-tube suction mode, the waste liquid suction and discharge structure can more thoroughly pump and discharge the waste liquid and the washing liquid, and the washing effect is better.
According to the invention, the hair washing liquid injection structure and the waste liquid suction and discharge structure are combined together and then moved into the solid phase micropore, so that the flushing and suction actions can be synchronously carried out or rapidly and alternately carried out, and the flushing and suction actions can be rapidly completed in a short time.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it should be understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and for those skilled in the art, other related drawings can be obtained according to the drawings without inventive efforts.
FIG. 1 is a schematic structural diagram of a hair washing device of a solid-phase micro-porous reactor provided in example 1 of the present invention.
Fig. 2 is a schematic structural diagram of an assembled liquid injection structure and a waste liquid suction and discharge structure for hair washing provided in embodiment 1 of the present invention.
Fig. 3 is a schematic structural diagram of a nut of a hair washing liquid filling pipe according to embodiment 1 of the present invention.
Fig. 4 is a schematic structural diagram of a solid-phase micro-hole and epitaxial rim provided in example 1 of the present invention.
Fig. 5 is a schematic structural diagram of a solid-phase micro-hole and epitaxial rim provided in example 2 of the present invention.
Fig. 6 is a schematic structural diagram of a solid-phase micro-hole and epitaxial edge matching structure provided in embodiment 3 of the present invention.
Detailed Description
The embodiments of the present invention are within the scope of the present invention. Thus, the following detailed description of the embodiments of the present invention, presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be obtained by a person skilled in the art without any inventive step based on the embodiments of the present invention, are within the scope of the present invention.
In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and are not to be construed as indicating the purposes, technical solutions and advantages of the embodiments of the present invention, which will be described in detail and fully with reference to the accompanying drawings in the embodiments of the present invention. All other implementations that can be derived by one of ordinary skill in the art based on the embodiments of the present invention show or imply relative importance or implicitly indicate the number of technical features indicated, without inventive step. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
The first embodiment is as follows:
referring to fig. 1-6, a solid phase micro-porous reactor hair washing device comprises: the solid-phase micropore 1 is open at the top and is hollow, the solid-phase micropore 1 comprises a micropore cavity 11, the top of the micropore cavity 11 is provided with a pore edge 13, and the bottom surface of the micropore cavity 11 is provided with a gain structure 12;
the liquid injection structure 2 of the shampoo, including deepening into the pore cavity of the micropore and washing the liquid cavity 21 that is set up with the interval of inner sidewall of pore cavity 11 of the micropore, the perimeteric surface of the said washing liquid cavity 21 extends outside and has a platform along 22 set up in the top of the said hole along 13, both ends of the axial of the said washing liquid cavity 21 have upper openings and lower openings separately, there is liquid injection pipe 23 of the external liquid injection structure that connects by the liquid injection pipe nut 4 of the shampoo on the top of the said washing liquid cavity 21;
the waste liquid suction and discharge structure 3 vertically penetrates through the upper opening and the lower opening of the washing liquid cavity 21, the waste liquid suction and discharge structure 3 comprises a waste liquid leading-out cavity 31 positioned in a flushing area formed by the micropore pore cavity 11 and the washing liquid cavity 21, an extension edge 32 is axially connected to one side, extending into the micropore pore cavity 11, of the waste liquid leading-out cavity 31, the shape of the extension edge 32 is matched with the shape of the gain structure 12, and the distance between the extension edge 32 and the bottom and the inner side wall of the micropore pore cavity 11 is not more than 1mm, so that washing liquid on the bottom of the micropore pore cavity and the surface of the inner side wall can be fully washed when flowing.
Establish including the lid further the liquid pipe nut 4 is annotated to the washing head that solid phase micropore 1 one side was kept away from to washing liquid chamber 21, it establishes to wash head notes liquid pipe nut 4 cover it annotates liquid structure 2, waste liquid suction structure 3's top and constitutes an airtight space 41 to wash head, wash head notes has seted up the confession on the liquid pipe nut 4 it derives the round hole 42 that chamber 31 passes through and supplies to wash head the through-hole 43 that liquid pipe 23 passes through.
When the device is installed, a washing liquid filling path is communicated with the liquid filling pipe 23 on the washing liquid cavity 21, then a waste liquid pumping and draining path is communicated with the top of the waste liquid guide cavity 31, and meanwhile, the top of the hair washing liquid filling structure 2 is sealed through the hair washing liquid filling pipe screw cap 4 to form a closed space 41, so that a better environment is provided for pressurization of liquid filling and liquid pumping.
In some existing flushing structures, a pumping and draining structure is often installed firstly, pumping and draining actions are performed, then the pumping and draining structure is taken out, then a washing liquid filling structure is installed, washing liquid actions are performed, then a washing liquid filling structure is taken out, then the pumping and draining structure is installed for suction, thus a lot of time is consumed in the installation and removal processes, in the embodiment, in the combination process of the head washing liquid injection structure 2 and the waste liquid suction and drainage structure 3, the waste liquid suction and drainage structure 3 is fixed inside the head washing liquid injection structure 2 through a connecting piece, so that the head washing liquid injection structure 2 and the waste liquid suction and drainage structure are integrated, therefore, after the head washing liquid injection structure 2 is installed at a proper position, the waste liquid suction and drainage structure 3 is also installed at a proper position, two times of alignment are not needed, the installation and debugging time is saved, and the two structures do not need to be taken out whether to work respectively or work simultaneously, not interfere with each other, but also cooperate with each other.
When liquid structure 2 and waste liquid suction and discharge structure 3 and solid phase micropore 1 cooperate in washing hair, at first, externally, through the location effect between the hole edge 13 at micropore vestibule 11 top and the recess 221 on the wash liquid chamber 21 platform edge 22, the position between liquid structure 2 and solid phase micropore 1 is annotated to washing hair has been fixed to owing to waste liquid suction and discharge structure 3 has been annotated liquid structure 2 with washing hair, so waste liquid suction and discharge structure 3 has also been in the same place with the gomphosis between solid phase micropore 1, specific gomphosis relation is: the shampoo cavity 21 of the shampoo filling structure 2 extends into the microporous pore cavity 11 of the solid-phase micropore 1, and a flushing area is formed between the shampoo cavity 21 and the microporous pore cavity 11, it needs to be emphasized that only part of the sidewall of the bottom surface of the shampoo cavity 21 is close to the inner sidewall of the microporous pore cavity 11 and does not extend into the microporous pore cavity 11, if the part of the sidewall extends into the microporous pore cavity 11, part of the lotion cannot flush with the inner sidewall of the microporous pore cavity 11 when guiding the lotion, and the waste liquid suction and discharge structure 3 is also obstructed, and the extension edge 32 of the waste liquid suction and discharge structure 3 can resist the descending of the inner sidewall of the microporous pore cavity 11 until the lotion is suspended above the gain structure 12 in the microporous pore cavity 11, and in the descending process, the waste liquid in the microporous pore cavity 11 is always squeezed to flow to the sidewall and flow to the bottom of the microporous pore cavity 11.
In some existing flushing structures, a capillary flushing and pumping manner is often adopted, that is, in the pumping process, the direction and angle need to be continuously adjusted to improve the pumping efficiency of the waste in the microporous cavity 11, but this pumping manner is often difficult to fully cover the inner surface of the entire microporous cavity 11, which easily causes part of the material to remain on the inner wall of the solid-phase micropore 1, and has to be repeatedly pumped and soaked, and the washing efficiency is poor, and the detection result is easily affected, while in this embodiment, the matching manner between the extension edge 32 and the microporous cavity 11 can move from the top of the inner side wall 11 of the microporous cavity to the gain structure 12 of the inner side wall, in this embodiment, the shape of the gain structure 12 is a plane, the shape of the extension edge 32 is also a plane, and the extension edge 32 will move to the bottom of the microporous cavity 11, and in the moving process, all waste liquid in the micropore pore cavity 11 is extruded to the inner side wall and the bottom of the micropore pore cavity 11 and then is pumped out in a suction mode, a suction area is formed between the extension edge 32 and the waste liquid guide cavity 31, liquid in a flushing area is pumped in the suction process, and at the moment, if flushing is carried out, a washing liquid is mixed with the waste liquid and is pumped out, and if flushing is not carried out, pure waste liquid is pumped out.
In the process of extraction, because the liquid injection structure 2 and the waste liquid suction and discharge structure 3 are combined together, when the device is used by a user, the user can select a simple suction and discharge mode, or a mode of cleaning while suction and discharge, or a rapid alternating mode of suction and discharge after suction and discharge and flushing or flushing before flushing, and no matter which mode is selected, the device does not need to take out another structure.
In order to guide the flowing direction of the washing liquid flowing out from the washing liquid cavity 21, the bottom of the washing liquid cavity 21 is an inclined angle 211 pointing to the microporous pore cavity 11, and an inclined plane of the inclined angle 211 faces the waste liquid suction and discharge structure 3, so that the washing liquid can be enabled to downwards flow along the inclined angle 211, the washing liquid which is flushed in can be enabled to downwards flow along the inner side wall of the microporous pore cavity 11, all waste liquid on the inner side wall of the microporous pore cavity is downwards flushed, and the washing efficiency is improved.
In order to improve the pumping efficiency, the height of the extension edge 32 is as low as possible, but it should be emphasized that, in order to avoid the extension edge 32 pressing against the gain structure 12 to damage the surface of the gain structure 12, the extension edge 32 should be parallel to the gain structure 12, and on the basis of the parallel arrangement, the distance between the two can be minimized, and at the same time, the extension edge 32 does not damage the gain structure 12 (if the gain structure 12 is damaged, the detection effect is affected).
The distance between the extension edge 32 and the inner side wall of the micropore cavity 11 is less than 1mm, so that the effect of squeezing the washing liquid to the inner side wall of the micropore cavity 11 can be achieved, meanwhile, the movable state can be achieved, and the reaction structure at the inner side wall and the bottom of the micropore cavity 11 is not damaged, and similarly, the distance between the extension edge 32 and the gain structure 12 is not only the effect of the maximum suction efficiency, but also the gain structure 12 is not damaged, namely, the distance between the extension edge 32 and the gain structure 12 is less than 1mm, preferably, the distance between the extension edge 32 and the inner side wall of the micropore cavity 11 and the distance between the extension edge 32 and the gain structure 12 are both 0.5-1 mm.
The embodiment also provides a use method of the solid-phase micro-porous reactor hair washing device, which comprises the following steps:
s1; a washing liquid filling path and a waste liquid pumping path are respectively connected with the through hole 43 of the liquid injection tube 23 and the circular hole 42 of the waste liquid leading-out cavity 31 to form a washing liquid flow path and a pumping flow path;
s2; starting the liquid pumping power of the waste liquid pumping and discharging path, embedding the extension edge 32 on the waste liquid guiding cavity 31 into the micropore cavity 11, simultaneously clamping the hole edge 13 of the micropore cavity 11 into the groove 221 of the platform edge 22, embedding the liquid washing cavity 21 into the inner wall of the micropore cavity 11, extruding the substances to be pumped on the inner wall of the micropore cavity 11 to the bottom in the clamping process of the extension edge 32, and preparing for washing liquid in an early stage;
s3; starting the liquid injection power of the washing liquid filling path, introducing the washing liquid into the washing liquid cavity 21 through the washing liquid flow path, flowing into the washing area along the inclined surface, and washing the inner side wall of the micropore cavity 11 and the gain structure 12;
s4; after the washing is finished, washing liquid is led into a gap between the extension edge 32 and the gain structure 12 through the outer part of the extension edge 32, and the washed liquid is discharged from the waste liquid outlet cavity 31, and the liquid can be pumped and the washing liquid can be alternately carried out or simultaneously carried out.
Example two:
the present embodiment is substantially the same as the first embodiment, except that:
referring to fig. 5, the gain structure 12 is a rotating body, and in order to increase the surface area of contact, the gain structure 12 is configured as a rotating body, and correspondingly, the extension edge 32 in this embodiment is a hollow circular truncated cone structure with openings at both ends, and the circular truncated cone structure is covered over the entire rotating body, so that the extension edge 32 can be adapted to the shape of the rotating body, and the suction efficiency thereof is improved.
It should be emphasized that, because of the requirement of immunoassay, the gain structure 12 needs to be set as a rotating body to increase the surface area, and on the contrary, because of the rotating body structure, there are problems of difficult suction, incomplete suction and the like during suction because of the special-shaped structure thereof, and after the extension edge 32 corresponding to the gain structure is adopted, the negative pressure generated from the waste liquid lead-out cavity sucks at the extension edge 32, and the shape of the extension edge 32 matches with the gain structure 12, so that the waste liquid on the gain structure 12 can be thoroughly carried away, and the suction efficiency is ensured.
Example three:
the present embodiment is substantially the same as the first and second embodiments, and the difference is that:
referring to fig. 6, the gain structure 12 is a rotator with a groove 221, and similarly, in order to increase the contact surface area, the gain structure 12 is a rotator with a groove 221, and like the embodiment, the extension edge 32 in this embodiment is also a hollow truncated cone structure with openings at both ends, but since the groove 221 is formed in the rotator, the height of the whole body is reduced, accordingly, the height of the extension edge 32 is also reduced, the concentration point of negative pressure in the pumping is also reduced, the extension edge 32 can be adapted to the shape of the rotator, and the pumping efficiency is improved.
Although the shapes of the gain structure 12 and the extension edge 32 are limited in the above embodiments, the shapes of the gain structure 12 and the extension edge 32 are only exemplified, and in fact, the extension edge 32 needs to be adjusted in shape and size according to the shapes and structures of the gain structure 12 and the micropore cavity 11, and the extension edge 32 is always matched with the gain structure 12 and the micropore cavity 11.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (10)

1. A solid phase micropore reactor device of washing hair, characterized in that includes:
the solid phase micropore with an opening at the top comprises a micropore pore cavity, the top of the micropore pore cavity is provided with a pore edge, and the bottom surface of the micropore pore cavity is provided with a gain structure;
the washing liquid injection structure comprises a washing liquid cavity which is deep into the micropore cavity and is arranged at an interval with the inner side wall of the micropore cavity, the outer peripheral surface of the washing liquid cavity extends outwards to form a platform edge which is erected at the top of the hole edge, the two axial ends of the washing liquid cavity are respectively provided with an upper opening and a lower opening, and the top of the washing liquid cavity is provided with a liquid injection pipe which is externally connected with an external liquid injection structure through a washing liquid injection pipe nut;
the waste liquid suction and discharge structure vertically penetrates through the upper opening and the lower opening of the washing liquid cavity, the waste liquid suction and discharge structure comprises a waste liquid leading-out cavity positioned in a washing area formed by the micropore pore cavity and the washing liquid cavity, the side wall of the waste liquid leading-out cavity extending into the micropore pore cavity is axially connected with an extension edge, the shape of the extension edge is matched with the shape of the gain structure, and the extension edge keeps a distance of not more than 1mm with the bottom and the inner side wall of the micropore pore cavity, so that washing liquid on the bottom of the micropore pore cavity and the surface of the inner side wall can be sufficiently washed when flowing.
2. The solid-phase micropore reactor hair washing device of claim 1, further comprising a cap disposed on a hair washing liquid injection pipe nut on one side of the liquid washing cavity away from the solid-phase micropores, wherein the hair washing liquid injection pipe nut is sleeved on the tops of the hair washing liquid injection structure and the waste liquid suction and discharge structure to form a closed space, and the hair washing liquid injection pipe nut is provided with a round hole for the waste liquid to be led out from the cavity and a through hole for the liquid injection pipe to pass through.
3. The solid phase micro-well reactor hair washing device as claimed in claim 2, wherein the platform edge is provided with a groove at one side close to the solid phase micro-well, and the groove of the platform edge is matched with the hole edge of the solid phase micro-well.
4. The solid phase microporous reactor hair washing apparatus of claim 2, wherein the bottom of the washing liquid chamber is an inclined angle directed to the microporous cavity, and the inclined plane of the inclined angle is directed to the waste liquid suction and discharge structure.
5. The solid-phase microporous reactor hair washing device according to claim 1, wherein the outer wall of the waste liquid suction and discharge structure is fixed on the inner wall of the hair washing liquid injection structure through a connecting piece.
6. The solid-phase micro-porous reactor hair washing device as claimed in claim 5, wherein the extension edge is always parallel to the gain structure forming surface when the waste liquid suction and discharge structure is matched with the solid-phase micro-pores.
7. The solid-phase microporous reactor hair washing device of claim 6, wherein the distance between the extension edge and the gain structure is less than 1mm, and the distance between the extension edge and the inner side wall of the microporous cavity is less than 1 mm.
8. The solid phase micro-porous reactor hair washing apparatus of claim 5, wherein the shape of the gain structure is a plane, a rotating body, or a rotating body with a notch.
9. The solid-phase micro-porous reactor hair washing device of claim 6, wherein the height of the extension edge is increased or decreased with the shape change of the gain structure.
10. A method of using a solid phase micro-porous reactor hair washing device comprising a solid phase micro-porous reactor hair washing device as claimed in any one of claims 1 to 9, wherein:
s1; a washing liquid filling liquid path and a waste liquid pumping and discharging liquid path are respectively connected with the through hole of the liquid injection pipe and the round hole of the waste liquid guide cavity to form a washing liquid flow path and a pumping and discharging flow path;
s2; starting the liquid pumping power of the waste liquid pumping and discharging liquid path, embedding the extension edge on the waste liquid guide cavity into the micropore cavity, simultaneously clamping the hole edge of the micropore cavity into the groove of the platform edge, embedding the washing liquid cavity into the inner wall of the micropore cavity, extruding the substances to be pumped in the micropore cavity to the side wall and the bottom of the extension edge in the clamping process, and completing pumping of unreacted substances or waste liquid;
s3; starting the liquid injection power of the washing liquid filling liquid path, introducing the washing liquid into the washing liquid cavity through the washing liquid flow path, flowing into the washing area along the inclined surface, and washing the inner side wall of the micropore cavity and the bottom gain structure;
s4; after the washing is finished, the washing liquid is discharged from the waste liquid guide cavity through gaps among the outer edge of the extension edge, the inner side wall of the micropore cavity and the bottom gain structure, and the liquid can be alternately pumped and the washing liquid can be simultaneously carried out.
CN202210111287.XA 2022-01-29 2022-01-29 Hair washing device of solid-phase micropore reactor and use method Active CN114515733B (en)

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CN202210111287.XA CN114515733B (en) 2022-01-29 2022-01-29 Hair washing device of solid-phase micropore reactor and use method

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US5592959A (en) * 1993-12-20 1997-01-14 Toa Medical Electronics Co., Ltd. Pipet washing apparatus
JPH10328634A (en) * 1997-05-28 1998-12-15 Naotaka Nakamura Suction hole of suction section at end of cleaning tool for cleaning black sludge among small stones accumulated on bottom of water tank, pond or the like
JP2014070915A (en) * 2012-09-27 2014-04-21 Tosoh Corp Liquid sucking method, and solid phase washing method using the same
CN204769670U (en) * 2015-07-14 2015-11-18 厦门先明生物技术有限公司 Washing device of immunodetection analytical instrument
CN209006249U (en) * 2018-09-11 2019-06-21 深圳市新产业生物医学工程股份有限公司 Diagnositc analyser and its cleaning assembly
CN110076155A (en) * 2018-01-25 2019-08-02 深圳市新产业生物医学工程股份有限公司 Cleaning assembly, wiper mechanism and chemiluminescence detector
CN211576967U (en) * 2019-11-19 2020-09-25 苏州长光华医生物医学工程有限公司 Cleaning needle imbibition needle structure with good cleaning effect
CN213856173U (en) * 2020-10-23 2021-08-03 深圳雷杜生命科学股份有限公司 Simple biochemical reaction cup cleaning module and cleaning device
CN213856203U (en) * 2020-10-23 2021-08-03 深圳雷杜生命科学股份有限公司 Biochemical reaction cup cleaning module and cleaning device

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5592959A (en) * 1993-12-20 1997-01-14 Toa Medical Electronics Co., Ltd. Pipet washing apparatus
JPH10328634A (en) * 1997-05-28 1998-12-15 Naotaka Nakamura Suction hole of suction section at end of cleaning tool for cleaning black sludge among small stones accumulated on bottom of water tank, pond or the like
JP2014070915A (en) * 2012-09-27 2014-04-21 Tosoh Corp Liquid sucking method, and solid phase washing method using the same
CN204769670U (en) * 2015-07-14 2015-11-18 厦门先明生物技术有限公司 Washing device of immunodetection analytical instrument
CN110076155A (en) * 2018-01-25 2019-08-02 深圳市新产业生物医学工程股份有限公司 Cleaning assembly, wiper mechanism and chemiluminescence detector
CN209006249U (en) * 2018-09-11 2019-06-21 深圳市新产业生物医学工程股份有限公司 Diagnositc analyser and its cleaning assembly
CN211576967U (en) * 2019-11-19 2020-09-25 苏州长光华医生物医学工程有限公司 Cleaning needle imbibition needle structure with good cleaning effect
CN213856173U (en) * 2020-10-23 2021-08-03 深圳雷杜生命科学股份有限公司 Simple biochemical reaction cup cleaning module and cleaning device
CN213856203U (en) * 2020-10-23 2021-08-03 深圳雷杜生命科学股份有限公司 Biochemical reaction cup cleaning module and cleaning device

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