CN114515321A - 一种温阳暖宫膏方及其应用 - Google Patents

一种温阳暖宫膏方及其应用 Download PDF

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Publication number
CN114515321A
CN114515321A CN202210147149.7A CN202210147149A CN114515321A CN 114515321 A CN114515321 A CN 114515321A CN 202210147149 A CN202210147149 A CN 202210147149A CN 114515321 A CN114515321 A CN 114515321A
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parts
warming
yang
pulp
white
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CN114515321B (zh
Inventor
张晓天
余佩思
余承鸿
韦硕硕
唐嘉仪
姜凡
王莹
王雪莹
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Shuguang Hospital Affiliated to Shanghai University of TCM
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Shuguang Hospital Affiliated to Shanghai University of TCM
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Abstract

本发明涉及一种温阳暖宫膏方，其由以下重量份配比的原料药制备而成：高丽红参80‑100份、白人参90‑110份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药140‑160份、白茯苓190‑210份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、阿胶120份、鹿角胶120份、饴糖250份、白蜜250份、黄酒250份。本发明还提供了温阳暖宫膏方的用途。本发明温肾助阳，益气健脾，养心安神。

Description

一种温阳暖宫膏方及其应用
技术领域
本发明涉及中药领域，具体地说，涉及一种温阳暖宫膏方及其应用。
背景技术
中医养生膏方是一种将根据中医原理将中药饮片反复煎煮，去渣取汁，经蒸发浓缩后，加糖、蜂蜜或阿胶等制成的半流体剂型，针对体虚易感者，亚健康状态，慢性疾病，儿童、女性、老年人等特殊人群有良好效果，在现代临床上的应用愈加广泛。
《内经·素问》曰：“阳气者，若天与日，失其所则折寿而不彰。”阳气，是人体生长、发育以及进行各种生命活动的动力之源。女性的生理特点是经、带、胎、产、乳，这些生理功能都与血密切相关，而血分不足或血脉凝涩瘀滞都有可能导致妇科疾病的产生。《景岳全书·妇人规·经脉诸脏病因》说：“女子以血为主，血旺则经调子嗣……故治妇人病当以经血先。”而血“得温则行，遇寒则凝”，也就是说血的正常运行有赖于阳气的温煦和推动。
中国专利文献CN104815307A，公开了一种温阳暖宫包，所述温阳暖宫包按照重量份的组成包括：穿山甲10克、炮姜20克、桂枝20克、元胡30克、艾叶20克、石楠叶30克、乳香20克、没药20克、紫石英60克、红花25克、白芷50克、当归20克、蛇床子60克、白芥子25克、小茴香60克、吴茱萸20克、透骨草50克、川芎30克、路路通15克、冰片3克、青皮30克；按上述组成的原料制成规格为568g/袋的药包，使用时将药包置入凉水中浸泡半小时，再通过水蒸或微波炉加热，最后放在小腹上热敷30-40分钟，本发明主治妇女各种小腹疼痛，通过热敷小腹能产生较强的温经通络，散寒止疼的功效，具有消炎杀菌、暧宫去寒、增强自身免疫力、调节内分泌、淡化皱纹、保养卵巢，延缓衰老等治疗和辅助作用。
而目前关于疗效显著，副作用小的一种温阳暖宫膏方还未见报道。
发明内容
本发明的目的是针对现有技术中的不足，提供一种温阳暖宫膏方。
本发明的再一的目的是，提供所述温阳暖宫膏方的用途。
为实现上述第一个目的，本发明采取的技术方案是：一种温阳暖宫膏方，其由以下重量份配比的原料药制备而成：高丽红参80-100份、白人参90-110份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药140-160份、白茯苓190-210份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、阿胶120份、鹿角胶120份、饴糖250份、白蜜250份、黄酒250份。
优选地，温阳暖宫膏方，其由以下重量份配比的原料药制备而成：高丽红参85-95份、白人参95-105份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药145-155份、白茯苓195-205份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、阿胶120份、鹿角胶120份、饴糖250份、白蜜250份、黄酒250份
更优选地，温阳暖宫膏方，其由以下重量份配比的原料药制备而成：高丽红参90份、白人参100份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药150份、白茯苓200份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、阿胶120份、鹿角胶120份、饴糖250份、白蜜250份、黄酒250份。
为实现上述第二个目的，本发明采取的技术方案是：
如上任一所述的温阳暖宫膏方在制备改善或治疗月经期疾病、孕期疾病、哺乳期疾病、妇科疾病的食品、保健品或药物中的应用。
优选地，所述的月经期疾病是闭经、痛经，所述的孕期疾病是习惯性流产、先兆流产；所述的哺乳期疾病是恶露淋漓不尽、产后腹痛、产后身痛；所述的妇科疾病是不孕、子宫肌瘤、阴道炎。
本发明优点在于：
1、本发明治疗原则：温肾助阳，益气健脾，养心安神
配伍关系：将四君子汤、右归丸、四物汤、保元汤加减化裁，方中用生炙黄芪、肉苁蓉、补骨脂、肉桂、鹿角胶、仙灵脾、嫩仙茅、紫石英补气温阳，黄芪生用善于补一身之气，兼有升阳固表之功，肉桂补火助阳，散寒止痛，温经通脉，补骨脂、肉苁蓉、鹿角胶温阳益精，仙灵脾、仙茅补肾暖宫，紫石英安神暖宫。厚杜仲、女贞子、菟丝子、枸杞子补益肝肾。共奏君药之效。熟地黄、全当归、阿胶、炒川芎有养血调经之功，张景岳著《妇人归》曰“妇人所重在血，血能构精，胎孕乃成”；熟地黄为滋补肝肾阴血之要药，补血滋阴，益精填髓，当归甘温质润，为妇科要药和补血要药，既能补血活血，又能调经止痛，阿胶补血滋阴，白芍舒肝止痛，炒川芎既能活血化瘀，又能行气，为“血中之气药”，为臣药。高丽红参、白人参、炒白术、白茯苓、淮山药、生熟薏苡仁益气健脾，红参配白参大补元气，补脾益肺，炒白术燥湿健脾，益气安胎，白茯苓配苡仁利水渗湿，益脾和胃，怀山药健脾益气，扶正固本，为佐药。大红枣、莲子肉、核桃肉、桂圆肉养心安神，黑芝麻补益精血，炙甘草、饴糖、白蜜益气调中，扶助正气，黄酒引经助药上行，调和诸药，为使药。
本发明主要治疗的疾病：月经期疾病：月经后期、闭经、痛经等；孕期疾病：习惯性流产、先兆流产等；哺乳期：恶露淋漓不尽、产后腹痛、产后身痛；妇科杂病：不孕、子宫肌瘤、阴道炎等育龄期人群。
使用方法：
膏方服用剂量要根据病情或患者的身体情况及药物性质决定，与患者消化功能关系非常密切。一般应从小剂量开始，逐渐加量，如成人每日先服一汤匙，约10-15克，如果消化功能正常，1周后改为1天服两次，即早晨起床后与晚上睡前1小时各空腹服用1次。
2、动物实验表明本发明温阳暖宫膏方对于寒凝血瘀模型大鼠有明显的作用，效果显著。
3、本发明通过调节卵巢血管舒-缩因子ET-1、Ang-2、CGRP、NO的活性,改善卵巢血液供应,促进卵巢发育,调节E2、P、T水平,从而达到治疗月经期疾病、孕期疾病、哺乳期疾病、妇科疾病的目的。
具体实施方式
下面对本发明提供的具体实施方式作详细说明。
实施例1本发明温阳暖宫膏方的制备(一)
高丽红参90份、白人参100份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药150份、白茯苓200份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例2本发明温阳暖宫膏方的制备(二)
高丽红参90份、白人参90份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药160份、白茯苓195份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例3本发明温阳暖宫膏方的制备(三)
高丽红参80份、白人参110份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药145份、白茯苓205份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例4本发明温阳暖宫膏方的制备(四)
高丽红参100份、白人参95份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药155份、白茯苓200份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例5本发明温阳暖宫膏方的制备(五)
高丽红参85份、白人参105份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药150份、白茯苓190份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例6本发明温阳暖宫膏方的制备(六)
高丽红参95份、白人参100份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药140份、白茯苓210份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例7本发明温阳暖宫膏方的制备(七)
高丽红参90份、白人参110份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药145份、白茯苓200份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例8本发明温阳暖宫膏方的制备(八)
高丽红参80份、白人参95份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药155份、白茯苓190份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例9本发明温阳暖宫膏方的制备(九)
高丽红参100份、白人参105份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药150份、白茯苓210份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例10本发明温阳暖宫膏方的制备(十)
高丽红参85份、白人参100份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药140份、白茯苓195份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例11本发明温阳暖宫膏方的制备(十一)
高丽红参95份、白人参90份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药160份、白茯苓205份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、鹿角胶120份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份，融化收膏。
实施例12温阳暖宫膏方对对寒凝血瘀模型大鼠的实验研究
1.1动物
选用健康清洁级SD雌性大鼠40只,鼠龄3个月,体重230g±20g,由上海中医药大学实验动物中心提供。适应性饲养2周后,按随机数字表法将其分为4组,每组10只,即正常对照组(正常组)、模型对照组(模型组)、中药对照组、本发明温阳暖宫膏方组1。
1.2试验药物
中药对照组：中药组成如下：高丽红参90份、白人参100份、生黄芪150份、炙黄芪150份、淮山药150份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、酒锁阳100份、紫石英150份、川肉桂30份、熟附子20份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份，上药浓煎去渣，取浓汁入阿胶120份、饴糖250份、白蜜250份、黄酒250份。给药时用蒸馏水配制成溶液。
本发明温阳暖宫膏方组1：按照实施例1所述的方法制备。给药时用蒸馏水配制成溶液。
1.3分组及造模
适应性饲养2周后,按随机数字表法将其分为4组,每组10只,即正常对照组(正常组)、模型对照组(模型组)、中药对照组、本发明温阳暖宫膏方组1。
寒凝血瘀动物模型的建立造模方法采用冰水冷冻的方法。将模型组、中药对照组、本发明温阳暖宫膏方组1大鼠置于0℃～1℃冰水中20分钟，每日1次，连续2周，大鼠出现蜷缩少动，反应迟钝，爪尾部紫暗，耳色暗红，喜扎堆，呼吸微弱，被毛无光泽，饮水量少，小便色清，大便溏泻等症状，造成寒凝血瘀大鼠模型。
1.4给药方式
在成功建模后，对每组中的大鼠进行称重，对每组进行不同干预。
正常对照组:正常组常规饲养。给予同体积(本发明温阳暖宫膏方组1同体积)的蒸馏水。
模型组:大鼠置于0℃-1℃冰水中20min，每日1次,连续2周。2周后给予同体积(本发明温阳暖宫膏方组1同体积)的蒸馏水。
中药对照组:大鼠置于0℃-1℃冰水中20min,每日1次,连续2周。2周后按10g生药/(kg·d)-1的剂量给予相应药液灌胃，其中所述生药为除糖和黄酒以外的原料；连续灌胃14天。
本发明温阳暖宫膏方组1:大鼠置于0℃-1℃冰水中20min,每日1次,连续2周。2周后按10g生药/(kg·d)-1的剂量给予相应药液灌胃，其中所述生药为除糖和黄酒以外的原料；连续灌胃14天。
1.5观察及统计
①血清孕酮(P)、雌二醇(E2)、睾酮(T)激素含量测定:灌胃14天后,于动情间期断头取血,离心取上清,采用放射免疫法测定血清P、E2、T；②卵巢组织血管舒-缩因子活性检测:迅速剖取卵巢,剔除周围组织,分别加入预冷的0.1mol LKH2PO4缓冲液(pH＝7.4),制成10％的组织匀浆,4℃3000rmin离心5min,取上清分装,采用放射免疫法测定内皮素-1(ET-1)、血管紧张素-Ⅱ(Ang-2)、降钙素基因相关肽(CGRP)、利用硝酸还原酶法测定一氧化氮(NO)。
统计方法
采用SPSS21.0计软件处理数据，各组统计资料均以
Figure BDA0003508742720000082
表示。
1.6结果
大鼠血清P、E2、T的含量变化见表1
表1大鼠血清P、E2、T的含量(x±s)
Figure BDA0003508742720000081
Figure BDA0003508742720000091
注:与正常组比较:＊P<0.01；与模型组比较:△P<0.01
表1显示,模型组大鼠的血清E2、P、T与正常组比较均有所降低(＊P<0.01)。中药对照组E2、P升高,本发明温阳暖宫膏方组1的E2、P、T均升高,与模型组比较差异有统计学意义(均P<0.01)。
本发明能够调节卵巢局部血管的舒缩功能。大鼠血清ET-1、NO、Ang-2、CGRP活性变化见表2
表2大鼠卵巢组织ET-1、NO、Ang-2、CGRP活性
Figure BDA0003508742720000092
注:与正常组比较:＊P<0.05；与模型组比较:△P<0.05
表2显示,模型组大鼠卵巢组织ET-1、Ang-2活性升高,NO、CGRP活性降低,与正常组比较显著性有统计学意义(均P<0.05)；中药对照组、本发明温阳暖宫膏方组1的ET-1、Ang-2均减低,NO、CGRP均升高,二者比较有统计学意义(均P<0.05)。
本发明可能通过调节卵巢血管舒-缩因子ET-1、Ang-2、CGRP、NO的活性,改善卵巢血液供应,促进卵巢发育,调节E2、P、T水平,从而达到治疗月经期疾病、孕期疾病、哺乳期疾病、妇科疾病的目的。
血管收缩-舒张因子在妇科疾病的发生发展中有着重要意义,根据寒为阴邪,性主收引凝滞,得温则缓的特点,我们观察了温阳暖宫膏方对模型大鼠对卵巢局部血管收缩-舒张因子的作用。结果显示，模型组卵巢组织血管收缩因子ET-1、Ang-2活性升高，舒张因子NO、CGRP活性降低；中药对照组、本发明温阳暖宫膏方组1ET-1、Ang-2均减低,NO、CGRP均升高,说明本发明能够调节卵巢局部血管的舒缩功能。生殖器官的血液供应与卵泡的发育和生殖激素的水平有密切的关系,而温阳暖宫膏方可能通过调节卵巢血管舒缩因子ET-1、Ang-2、CGRP、NO的活性,改善卵巢血液供应,促进卵巢发育,调节E2、P、T水平,从而达到治疗寒凝血瘀妇科疾病的目的。
以上所述仅是本发明的优选实施方式，应当指出，对于本技术领域的普通技术人员，在不脱离本发明方法的前提下，还可以做出若干改进和补充，这些改进和补充也应视为本发明的保护范围。

Claims (5)

1.一种温阳暖宫膏方，其特征在于，其由以下重量份配比的原料药制备而成：高丽红参80-100份、白人参90-110份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药140-160份、白茯苓190-210份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、阿胶120份、鹿角胶120份、饴糖250份、白蜜250份、黄酒250份。
2.根据权利要求1所述的温阳暖宫膏方，其特征在于，其由以下重量份配比的原料药制备而成：高丽红参85-95份、白人参95-105份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药145-155份、白茯苓195-205份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、阿胶120份、鹿角胶120份、饴糖250份、白蜜250份、黄酒250份。
3.根据权利要求2所述的温阳暖宫膏方，其特征在于，其由以下重量份配比的原料药制备而成：高丽红参90份、白人参100份、生黄芪150份、炙黄芪150份、炒白术150份、淮山药150份、白茯苓200份、生苡仁200份、熟苡仁200份、补骨脂100份、肉苁蓉100份、仙灵脾150份、嫩仙茅90份、紫石英150份、川肉桂30份、熟地黄100份、厚杜仲100份、女贞子90份、枸杞子90份、菟丝子90份、全当归150份、炒川芎90份、炙甘草90份、大红枣100份、莲子肉100份、核桃肉100份、桂圆肉100份、黑芝麻100份、阿胶120份、鹿角胶120份、饴糖250份、白蜜250份、黄酒250份。
4.根据权利要求1-3任一所述的温阳暖宫膏方在制备改善或治疗月经期疾病、孕期疾病、哺乳期疾病、妇科疾病的食品、保健品或药物中的应用。
5.根据权利要求4所述的应用，其特征在于，所述的月经期疾病是闭经、痛经，所述的孕期疾病是习惯性流产、先兆流产；所述的哺乳期疾病是恶露淋漓不尽、产后腹痛、产后身痛；所述的妇科疾病是不孕、子宫肌瘤、阴道炎。
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