CN114514961A - Feed additive for preventing and treating parasitic diseases of pigeons, preparation method and application - Google Patents
Feed additive for preventing and treating parasitic diseases of pigeons, preparation method and application Download PDFInfo
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- CN114514961A CN114514961A CN202011307195.6A CN202011307195A CN114514961A CN 114514961 A CN114514961 A CN 114514961A CN 202011307195 A CN202011307195 A CN 202011307195A CN 114514961 A CN114514961 A CN 114514961A
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- pigeons
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- 208000030852 Parasitic disease Diseases 0.000 title claims abstract description 55
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/70—Feeding-stuffs specially adapted for particular animals for birds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/111—Aromatic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/174—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/189—Enzymes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Animal Husbandry (AREA)
- Zoology (AREA)
- Birds (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Physiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention belongs to the technical field of animal husbandry and veterinary medicine, and discloses a feed additive for preventing and treating parasitic diseases of pigeons, a preparation method and application thereof, wherein the feed additive is prepared by uniformly mixing compound amino acid, compound vitamin, Chinese herbal medicine, enzyme preparation, chitosan and beta-cyclodextrin; the additive is used for feeding pigeon to improve immunity and prevent/treat parasitic disease of pigeon. The components added in the invention are green and environment-friendly, have good effect after use and no residue, and can replace drugs or hormone feed additives to enhance the immunity of animals and increase the weight gain speed, prevent and treat parasitic diseases, shorten the growth period and promote the slaughtering in advance.
Description
Technical Field
The invention belongs to the technical field of animal husbandry and veterinary medicine, and relates to a feed additive and a preparation method thereof, in particular to a feed additive for preventing and treating parasitic diseases of pigeons, a preparation method and application.
Background
With the improvement of living standard, people not only can meet the consumption of food on fruit belly, but also more people pursue high-quality and health-care food, wherein the food with homology of medicine and food is welcomed, and young pigeons become one of the most popular food with homology of medicine and food due to higher nutritional value and medicinal value, but the wild number of the young pigeons is difficult to meet the requirements of people, and the ecological system is damaged due to over consumption of the wild young pigeons. In order to meet the edible requirements of people and protect the ecosystem, people carry out artificial domestication and artificial feeding on the young pigeons. However, in the process of artificially feeding young pigeons, the young pigeons are easy to suffer from various diseases such as parasitic diseases, so that the phenomenon of disease death before slaughtering occurs. In order to improve the breeding efficiency and shorten the slaughtering time, feeding personnel feed a large amount of antibiotics, antiparasitic drugs and hormone feed additives to reduce the morbidity of young pigeons. However, the medicine residue in the young pigeons is increased undoubtedly, and the quality of the young pigeons is reduced.
Disclosure of Invention
The invention aims to provide a feed additive for preventing and treating parasitic diseases of pigeons, so as to improve the immunity of young pigeons and prevent/treat the parasitic diseases of the pigeons;
the invention also aims to provide a preparation method of the feed additive for preventing and treating the pigeon parasitic disease;
the invention also aims to provide an application of the feed additive for preventing and treating the parasitic disease of the pigeons.
In order to achieve the purpose, the invention adopts the technical scheme that:
a feed additive for preventing and treating parasitic diseases of pigeons comprises the following raw materials in parts by weight:
compound amino acid: 0.3-1.5 parts of tryptophan, 0.1-1.0 parts of serine and 0.1-1.0 parts of threonine;
② complex vitamin: 0.05-0.4 part of biotin, 0.1-1.0 part of vitamin E, 0.1-1.0 part of nicotinamide and 0.1-1.0 part of vitamin A;
③ Chinese herbal medicine: 0.5-2.0 parts of purslane powder, 0.5-2.0 parts of American agrimony powder and 0.1-1.0 part of capsaicin;
enzyme preparation: 0.05-0.4 part of phytase, 0.05-0.4 part of amylase and 0.05-0.4 part of protease;
auxiliary materials: 0.8-2.0 parts of chitosan and 1-3 parts of beta-cyclodextrin.
As a limitation, the fineness of the Chinese herbal medicine is 80-100 meshes.
The invention also provides a preparation method of the feed additive for preventing and treating the parasitic disease of the pigeons, which is to uniformly mix all the raw materials to obtain the feed additive for preventing and treating the parasitic disease of the pigeons.
As a limitation, the uniformly mixing is to uniformly mix the compound amino acid and the compound vitamin, then add the Chinese herbal medicine and the auxiliary material to be uniformly mixed, and finally add the enzyme preparation to be uniformly mixed.
As another limitation, the feed additive for preventing and treating the parasitic disease of the pigeons needs to be vacuum-packaged.
The invention also provides an application of the feed additive for preventing and treating the pigeon parasitic disease, and the feed additive for preventing and treating the pigeon parasitic disease is used for feeding pigeons to improve the immunity and prevent/treat the pigeon parasitic disease.
As a limitation, the feed additive for preventing and treating the pigeon parasitic disease is added into feed.
Due to the adoption of the technical scheme, compared with the prior art, the invention has the technical progress that:
according to the feed additive for preventing and treating the pigeon parasitic diseases, the feed additive is obtained by compounding the compound amino acid, the compound vitamin, the enzyme preparation, the Chinese herbal medicine and the chitosan which are reasonably proportioned and taking the beta-cyclodextrin as a carrier, so that the immunity of the animal body is effectively improved, the parasitic diseases are prevented/treated, the production performance is improved, and the use of antibiotics and antiparasitic disease medicines is reduced/replaced;
wherein, the purslane is acid and cold in taste, enters liver and large intestine channels, and has the effects of clearing away heat and toxic materials, cooling blood and stopping bleeding and stopping dysentery; the western agrimony, also called agrimony, is bitter and astringent in taste, slightly warm and flat in nature, enters heart and liver channels, and has the effects of astringing to stop bleeding, stopping dysentery and killing parasites; capsaicin is also called capsaicin, and has the functions of diminishing inflammation, easing pain and improving immunity;
tryptophan, serine and threonine are also added in the invention. Tryptophan is an essential amino acid with the function of regulating the immunity of an organism, the microbial metabolite of the tryptophan has a profound effect on the immunity of intestinal mucosa, and the tryptophan is fed to the feed rich in tryptophan, has very important effects on improving the intestinal barrier and reducing infection, can participate in the renewal of plasma protein in the organism, can promote riboflavin to play a role, and is also beneficial to the synthesis of nicotinic acid and heme; threonine is an essential amino acid and is a third limiting amino acid of poultry, and the threonine is added into the feed, so that the amino acid balance of the feed can be adjusted, the growth of the poultry is promoted, the meat quality is improved, the nutritional value of the feed with low amino acid digestibility is improved, and the raw material cost of the feed can be reduced; serine, also known as beta-hydroxy alanine, is a non-essential amino acid that plays a role in the metabolism of fats and fatty acids and in muscle growth, contributes to the production of immunocytokines and antibodies, and maintains a healthy immune system. The three are matched, so that an intestinal barrier is established by improving the intestinal form, the nutrient absorption is promoted, the meat quality is improved, and the nutritional value of the pigeon meat is increased.
The phytase can decompose natural organic phosphorus in the feed, improve the nutritional value of minerals in the feed and the anti-nutritional effect of protein, and reduce phosphorus emission and environmental pollution while supplementing phosphorus elements;
the amylase promotes the decomposition of starch nutrient substances in the feed, improves the absorption and utilization rate of the organism, reduces the burden and energy consumption of the organism and reduces the feed conversion ratio;
the protease supplements the content of protease in the organism, promotes the conversion of protein in the feed to amino acid, improves the absorption utilization rate, promotes consumption and absorption, reduces the burden of the organism and energy consumption, and reduces the feed conversion ratio.
The addition of the three enzyme preparations promotes the utilization and absorption of organic phosphorus, starch and protein in the feed, reduces the feed-meat ratio, reduces the investment and environmental pollution and improves the production performance.
Biotin, also known as vitamin H and coenzyme R, is an essential substance for the synthesis of vitamin C, and is one of substances essential for the normal metabolism of fats and proteins. Biotin is a vital regulatory element for the xenogenesis of glycogen, the combined action of fatty acids and the metabolism of amino acids, and can also promote the synthesis of proteins by helping to generate energy; the biotin can assist cell growth, produce fatty acid, metabolize carbohydrate, fat and protein, is beneficial to the utilization of vitamin B group, promotes the health of sweat glands, nervous tissues, bone marrow and gonads, maintains the normal operation and growth of skin and hair, and improves the immunity;
the nicotinamide can provide required vitamins for organisms, and meanwhile, can maintain the stability of beneficial bacteria in intestinal tracts, promote the proliferation of the beneficial bacteria, improve the nonspecific immunity of the organisms and enhance the specific immunity;
the chitosan can maintain the stability of beneficial bacteria in intestinal tracts, promote the proliferation of the beneficial bacteria and improve the nonspecific immunity and the specific immunity of organisms;
beta-cyclodextrin is used as a carrier, can coat and stabilize each component, and maintains the stability of the compound amino acid and the enzyme preparation;
the components added in the invention are green and environment-friendly, have good effect after use and no residue, and can replace drugs or hormone feed additives to enhance the immunity of pigeons, increase the weight gain speed of pigeons, reduce the infection of parasitic diseases of pigeons, shorten the growth period and promote slaughter in advance;
the feed additive can replace part of antibiotics, reduce the loss of the breeding industry, reduce the harm of the drug feed additive to human bodies through a food chain, and provide safety protection for food;
the invention has wide raw material source and low cost, and can bring good economic benefit for breeding enterprises.
The feed additive for preventing and treating the pigeon parasitic diseases is used for being added into feed/health sand to feed pigeons, and is particularly suitable for feeding young pigeons.
Detailed Description
The present invention is further illustrated by the following specific examples, which are to be construed as merely illustrative, and not limitative of the remainder of the disclosure.
The phytase activity is more than or equal to 10000U/g, and is purchased from summer prosperous group; the amylase has the activity of more than or equal to 5000U/g and is purchased from Henan Jia navigation chemical products, Inc.; the protease activity is more than or equal to 10000U/g, and is purchased from Zhejiang Shengtong Biotechnology limited company.
Example 1 preparation method of a feed additive for preventing and treating parasitic diseases of pigeons
The feed additive for preventing and treating the parasitic disease of the pigeons is prepared by the embodiment, and comprises the following steps of:
1) 0.5kg of tryptophan, 0.5kg of serine and 0.5kg of threonine are uniformly mixed to obtain the compound amino acid.
0.2kg of biotin, 0.5kg of vitamin E, 0.8kg of nicotinamide and 0.5kg of vitamin A are uniformly mixed to obtain the compound vitamin.
Mixing 1.0kg of herba Portulacae powder with fineness of 80 mesh, 1.0kg of radix et caulis Opuntiae Dillenii powder with fineness of 80 mesh and 0.5kg of capsaicin with fineness of 100 mesh to obtain Chinese medicinal materials.
Uniformly mixing 0.2kg of phytase (the enzyme activity is more than or equal to 10000U/g), 0.2kg of amylase (the enzyme activity is more than or equal to 5000U/g) and 0.2kg of protease (the enzyme activity is more than or equal to 10000U/g) to obtain the enzyme preparation.
1.4kg of chitosan and 2kg of beta-cyclodextrin are uniformly mixed to obtain the auxiliary material.
2) Mixing compound amino acid and compound vitamin, adding Chinese herbal medicine mixed powder and adjuvants, mixing, adding enzyme preparation, mixing, vacuumizing, and storing in shade dry place to obtain feed additive for preventing and treating pigeon parasitic disease, labeled as N1.
The feed additive for preventing and treating the pigeon parasitic diseases prepared by the embodiment is used for being added into feed/health sand to feed pigeons, and is particularly suitable for feeding young pigeons.
Example 2-6 preparation method of feed additive for preventing and treating parasitic diseases of pigeons
Examples 2 to 6 are methods for preparing a feed additive for controlling parasitic diseases of pigeons, the steps of which are substantially the same as those of example 1, except for the difference in the amount of raw materials, and are specifically shown in table 1:
TABLE 1 feed additive for controlling parasitic diseases of pigeons
The contents of the other portions of examples 2 to 6 are the same as those of example 1.
Example 7 application of feed additive for controlling parasitic diseases of pigeons
Experiment of feed additive for preventing and treating parasitic disease of pigeons on shortening slaughtering time and preventing coccidiosis
The method comprises the steps of selecting 700 healthy coccidiosis-free fattening squabs aged 21 days, randomly dividing the fattening squabs into 7 groups, wherein each group comprises 100, namely a blank group and a test group A1-A6, wherein the blank group is used for feeding commercial squab feed (50 jin/bag of pigeon flying and growing nutrition feed), and the NA 1-NA 6 groups are used for feeding commercial squab feed (50 jin/bag of pigeon flying and growing nutrition feed) which is premixed with 1% of feed additives N1-N6 for preventing and treating pigeon parasitic diseases prepared in examples 1-6 one by one, feeding, managing and keeping health according to a conventional squab feeding program, wherein the test time is from 7/20 days in 2020 to 7/27 days in 2020, wherein the squabs reaching the marketing standard in the test period are continuously fed until the test is finished, so that the weight is increased better in a statistical manner.
During the test period and within 10 days after the test, the situation of the pigeon group is observed every day, the pigeon group is weighed once every day, the occurrence situation of coccidiosis is observed, whether the pigeon group reaches the marketing standard (the marketing standard is that the weight of the young pigeon reaches more than 500 g) or not is judged, the natural morbidity is counted, and the specific results are shown in a table 2:
TABLE 2 summary of the effects of feed additives for controlling parasitic diseases in pigeons on shortening the slaughtering time
After feeding for 7 days, the average body weight of the young pigeons in the test group reaches more than 540g, the coccidiosis incidence rate is obviously lower than that of the control group, the average body weight of the young pigeons in the blank group is only 490g, the coccidiosis incidence rate is 20%, the young pigeons in the test group reach the marketing standard after 7 days, marketing can be carried out in advance, only 24 young pigeons in the blank group reach the marketing standard, and the marketing age reaching the marketing standard is also obviously higher than that of the test group. The experimental results prove that the feed additive for preventing and treating the parasitic disease of the pigeons, prepared by the invention, can obviously prevent the coccidiosis of the young pigeons, improve the immunity, shorten the slaughtering time and improve the economic benefit.
Second) experiment of influence of feed additive for preventing and treating parasitic disease of pigeons on treatment of coccidiosis of young pigeons
The test is carried out in the experimental animal center of the company. Selecting 30 fattening young pigeons (40 young pigeons are artificially inoculated with the coccidiosis for toxin induction) infected by 16 days of age, randomly dividing the fattening young pigeons into 3 groups, and 10 each group respectively comprises a negative control group, a positive control group and an experimental group, wherein the negative control group feeds a commercial young pigeons feed (50 jin/bag of pigeon flight nutritional feed) without feeding medicaments for treating the coccidiosis, the positive control group feeds a Kochia scoparia, and the commercial young pigeons feed (50 jin/bag of pigeon flight nutritional feed) one by one, and the experimental group correspondingly feeds a commercial young pigeons feed (50 jin/bag of pigeon flight nutritional feed) premixed with 1 percent of the feed additive N1 for preventing and treating the pigeon parasitic diseases prepared in the embodiment 1 without feeding medicaments for treating the coccidiosis. The young pigeon is bred, managed and kept healthy according to the conventional breeding program, and the test time is from 7/15 days in 2020 to 22 days in 7/22 days in 2020.
During the test period, the pigeon flock and coccidiosis conditions are observed every day, the pigeon flock and coccidiosis conditions are weighed once a day, the treatment conditions of the sick young pigeons are counted, and the specific results are shown in a table 3:
TABLE 3 Table of the effect experiment of feed additive for preventing and treating parasitic diseases of pigeon on coccidiosis of young pigeon
| Group of | Negative control group | Positive control group | Experimental group |
| Young pigeon only number (only) | 10 | 10 | 10 |
| Young pigeon treated 7 days later has only one young pigeon treated | 0 | 8 | 6 |
| Cure rate (%) | 0 | 80 | 60 |
| 7 days later, the young pigeons died of illness are counted (only) | 4 | 1 | 2 |
| Mortality (%) | 40 | 10 | 20 |
| Initial average young pigeon body weight (g) | 314 | 310 | 298 |
| Average squab weight (g) 7 days later | 361 | 370 | 368 |
After 7 days of the experiment, the cure rate of the positive control group reaches 80 percent, the cure rate of the experimental group reaches 60 percent, and the negative control group has no self-healing young pigeon; the fatality rate of the positive control group is 10 percent, the fatality rate of the experimental group is 20 percent, and the fatality rate of the negative control group is as high as 40 percent; and the average weight gain of the young pigeons in the positive control group and the experimental group is higher than that in the negative control group. The experiments prove that the feed additive for preventing and treating the pigeon parasitic disease has the curative effect of treating the pigeon parasitic disease.
Thirdly) acute toxicological test of feed additive for preventing and treating parasitic diseases of pigeons
The feed additive for young pigeons provided in example 1 is added to feed for young pigeons of 16 days old in normal amount, 10 times, 50 times and 100 times, respectively, and the mixed feed for young pigeons is labeled as RCN 1-RCN 4, wherein the normal amount is the feed additive N1 which is added with 1.0% of the weight of the feed and is used for preventing and treating parasitic diseases of pigeons.
Selecting 50 healthy coccidiosis-free fattening young pigeons of 16 days old, randomly dividing the fattening young pigeons into 5 groups, wherein each group comprises 10 control groups and NC 1-NC 4 groups, wherein the control groups are used for feeding common commercial young pigeons, and the NC 1-NC 4 groups are used for feeding young pigeons with RCN 1-RCN 4, and the fattening young pigeons are fed in an unlimited manner in the whole day. The test time is from 11 days 6/2020 to 21 days 6/2020. Observing and recording the clinical reaction of the young pigeons in the feeding process, respectively and remotely inspecting the organ pathological changes of the young pigeons in each group after the feeding is finished, and displaying that all indexes of the young pigeons in the control group and the NC 1-NC 4 groups are normal without pathological changes. The experimental results prove that the feed additive for preventing and treating the pigeon parasitic disease prepared by the invention has no acute toxicity.
Claims (7)
1. The feed additive for preventing and treating the parasitic disease of the pigeons is characterized by comprising the following raw materials in parts by weight:
compound amino acid: 0.3-1.5 parts of tryptophan, 0.1-1.0 parts of serine and 0.1-1.0 parts of threonine;
② complex vitamin: 0.05-0.4 part of biotin, 0.1-1.0 part of vitamin E, 0.1-1.0 part of nicotinamide and 0.1-1.0 part of vitamin A;
(iii) Chinese herbal medicines: 0.5-2.0 parts of purslane powder, 0.5-2.0 parts of American agrimony powder and 0.1-1.0 part of capsaicin;
fourthly, enzyme preparation: 0.05-0.4 part of phytase, 0.05-0.4 part of amylase and 0.05-0.4 part of protease;
auxiliary materials: 0.8-2.0 parts of chitosan and 1-3 parts of beta-cyclodextrin.
2. The feed additive for preventing and treating the parasitic disease of the pigeons according to claim 1, wherein the fineness of the Chinese herbal medicines is 80-100 meshes.
3. A method for preparing a feed additive for preventing and treating parasitic diseases of pigeons according to claim 1 or 2, which is characterized in that all raw materials are uniformly mixed to obtain the feed additive for preventing and treating the parasitic diseases of the pigeons.
4. The preparation method of the feed additive for preventing and treating the parasitic disease of the pigeons according to claim 3, wherein the uniformly mixing is to uniformly mix the compound amino acid and the compound vitamin, then add the Chinese herbal medicines and the auxiliary materials to uniformly mix, and finally add the enzyme preparation to uniformly mix.
5. The method for preparing a feed additive for preventing and treating parasitic diseases of pigeons according to claim 3 or 4, wherein the feed additive for preventing and treating parasitic diseases of pigeons is further subjected to vacuum packaging.
6. The use of the feed additive for preventing and treating parasitic diseases of pigeons according to claim 1 or 2, wherein the feed additive for preventing and treating parasitic diseases of pigeons is used for feeding pigeons to improve immunity and prevent/treat parasitic diseases of pigeons.
7. The use of the feed additive for preventing and treating the parasitic disease of the pigeons according to claim 6, wherein the feed additive for preventing and treating the parasitic disease of the pigeons is used for being added into feed.
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