CN114505013B - Swinging type granulation machine for medicine production - Google Patents

Swinging type granulation machine for medicine production Download PDF

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Publication number
CN114505013B
CN114505013B CN202210009053.4A CN202210009053A CN114505013B CN 114505013 B CN114505013 B CN 114505013B CN 202210009053 A CN202210009053 A CN 202210009053A CN 114505013 B CN114505013 B CN 114505013B
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Prior art keywords
pipe
negative pressure
granulation machine
discharging pipe
production according
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CN202210009053.4A
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CN114505013A (en
Inventor
唐代凤
肖宁平
蔡义高
全玉康
李震
曾亚林
蒋石生
周华荣
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Hunan Timesun Pharmaceutical Co ltd
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Hunan Timesun Pharmaceutical Co ltd
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Priority to CN202210009053.4A priority Critical patent/CN114505013B/en
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms

Abstract

The invention discloses a swinging type granulation machine for medicine production, which comprises a base, a bracket on the base and a granulation mechanism on the bracket, wherein the lower end of the granulation mechanism is provided with a discharge pipe, the lower end of the discharge pipe is connected with one end of a negative pressure pipe, and the other end of the negative pressure pipe is connected with a boiling dryer. The invention can effectively solve the problem of continuous blanking, and can also solve the problem of particle adhesion in the conveying process, thereby greatly improving the production efficiency.

Description

Swinging type granulation machine for medicine production
Technical Field
The invention relates to the field of pharmaceutical appliances, in particular to a swinging granulation machine for medicine production.
Background
A swing granulator is a device that grinds wet powder or dry bulk material into desired granules. In the process of medicine production, the granulation of medicine is a common production flow, and when in granulation, medicine powder particles are uniformly mixed by using an adhesive, so that adhesive force is generated among the powder particles, and then the granules with a certain shape and size are formed under the action of an external machine. The swing type granulation machine is the most commonly used granulation equipment in the current pharmaceutical production.
The working principle of the swing type granulator during granulation is as follows: the seven-angle roller in the charging hopper is driven by the motor to repeatedly rotate, the part, provided with the leakage groove, of the bottom of the charging hopper is blocked by the screen mesh, the scraping plate is positioned on the screen mesh to extrude materials when the seven-angle roller rotates, and the materials are pressed to extrude the screen mesh to become a granular state. The existing swing type granulator usually directly falls into a collecting barrel from a feed opening to collect particles (such as a swing type granulator described in CN 215139651U) or directly adopts a conveying belt to convey the particles. The collecting barrel is adopted for collecting, so that materials are easy to fall off due to the swinging process of the swinging type granulator, the collecting barrel is replaced frequently, continuous granulation is affected, time and labor are wasted, a large amount of manpower is needed, and the production cost is high; if the material is directly conveyed by a conveying belt, the particles just coming out of the blanking opening still contain a certain amount of water, so that the adhesion force on the surface of the material is higher, and particularly, medicines with plant extract as raw materials are easy to cause particle bonding and pollution of the conveying belt, and the material is not easy to transfer from the conveying belt to the next process (drying process). Therefore, how to improve the discharging process of the swing type granulator is of great significance to improving the production efficiency.
Disclosure of Invention
The invention aims to overcome the defects of the prior art, and provides a swinging type granulation machine for medicine production, which can effectively solve the problem of continuous blanking, can also solve the problem of particle adhesion in the conveying process, and can greatly improve the production efficiency.
In order to solve the technical problems, the technical scheme provided by the invention is as follows: the utility model provides a medicine production is with swaing formula granulation machine, includes the granulation mechanism on support and the support on base, granulation mechanism's lower extreme is provided with the discharging pipe, the one end of negative pressure pipe is connected to the discharging pipe lower extreme, the other end and the boiling dryer of negative pressure pipe are connected.
According to the invention, the medicine particles in the discharging pipe are directly sucked into the boiling dryer through the negative pressure pipe, so that the conveying belt conveying and collecting processes are omitted, the problem of continuous discharging can be effectively solved, the problem of particle adhesion in the conveying process can be solved under the action of large negative pressure wind force, and the production efficiency can be greatly improved.
The invention provides a further technical scheme as follows: the anti-blocking mechanism is arranged in the discharging pipe, so that the blocking phenomenon in the discharging pipe can be avoided, the flow velocity problem of particles in the discharging pipe can be controlled through the anti-blocking mechanism, and the blocking phenomenon in the negative pressure pipe can be effectively avoided.
Further, the anti-blocking mechanism comprises a plurality of drawing plates made of light elastic materials, when the negative pressure pipe works, because of the existence of negative pressure, the drawing plates can incline towards the outlet of the discharging pipe, the inclination can not influence the falling of medicine particles in the discharging pipe, the inclination angle of the drawing plates can be 10 degrees generally, and the two symmetrical sides of the drawing plates are arranged in a staggered way; during normal use, projections of the tail ends of the drawing plates in the horizontal direction are overlapped, so that the route of the medicine particles in the discharge pipe is a curve, the anti-blocking effect can be achieved, the continuous rolling phenomenon of the granular medicine in the falling process can be achieved, further forming of the medicine is facilitated, and the adhesive force of the surfaces of the medicine particles is weakened; when the plug occurs, the drawing plate which is clung to the lower part of the plug is pulled out, and after the plug contacts, the drawing plate returns to the original position.
Further, the pull plate is provided with a handle at the tail end of the discharging pipe, so that the pull plate is convenient to pull.
Further, the distance between two adjacent drawing plates is 3-6 cm, and the medicine particles stably fall between the drawing plates.
Furthermore, the negative pressure pipe is formed by a plastic corrugated pipe, and the existence of the negative pressure pipe can not influence the normal work of the swing type granulation machine.
Further, the upper end of discharging pipe is equipped with down the hopper, the intercommunication has the hot-blast main on the hopper down, and the hot-blast main is connected with the air heater, under the combined action of negative pressure pipe and hot-blast main, hot-blast not only can not flow down the top of hopper and influence the granulation process of swinging granulator, but also can form hot-blast environment in hopper, discharging pipe and negative pressure pipe down, do benefit to the quick volatilization of medicine granule surface moisture, be favorable to eliminating the cohesive force on medicine granule surface, and then do benefit to the conveying process of medicine granule in the negative pressure intraductal smoothly going on.
Further, a screen for the falling of the medicine particles is arranged in the discharging hopper, the screen not only can play a role in controlling the falling speed of the medicine particles, but also is convenient for reducing the aggregation of the medicine particles in the falling process.
Further, the number of the screens is 1-3, when the number of the screens is more than one, the distance between the adjacent screens is not less than 10cm, enough space is reserved, and the phenomenon that medicine particles are blocked between the screens is avoided.
Further, the length of the discharging pipe is not less than 30cm, the path of the medicine particles in the discharging pipe is prolonged, and the phenomenon of blockage in the negative pressure pipe is avoided.
Compared with the prior art, the invention has the advantages that:
1. according to the invention, the medicine particles in the discharging pipe are directly sucked into the boiling dryer through the negative pressure pipe, so that the conveying belt transportation and collection processes are omitted, the problem of continuous discharging can be effectively solved, the problem of particle adhesion in the conveying process can be solved under the action of large negative pressure wind force, and the production efficiency can be greatly improved;
2. according to the invention, the anti-blocking mechanism is arranged in the discharging pipe, so that the blocking phenomenon in the discharging pipe can be avoided, the problem of controlling the flow rate of the medicine in the discharging pipe can be realized through the anti-blocking mechanism, and the blocking phenomenon in the negative pressure pipe can be effectively avoided;
3. according to the invention, the discharging hopper is arranged at the upper end of the discharging pipe, the hot air pipe is communicated with the discharging hopper, so that a synergistic effect of the hot air pipe and the negative pressure pipe can be formed, hot air can not only flow upwards of the discharging hopper to influence the granulating process of the swing granulator under the combined action of the negative pressure pipe and the hot air pipe, but also form a hot air environment in the discharging hopper, the discharging pipe and the negative pressure pipe, thereby facilitating quick volatilization of moisture on the surfaces of the medicine particles, facilitating elimination of adhesive force on the surfaces of the medicine particles, and further facilitating smooth carrying of the medicine particles in the negative pressure pipe.
Drawings
FIG. 1 is a schematic diagram of the structure of the present invention;
FIG. 2 is an enlarged sectional view of A-A in FIG. 1;
fig. 3 is an enlarged sectional view of B-B in fig. 1.
Legend description:
1. a bracket; 2. a base; 3. a granulating mechanism; 4. a discharge pipe; 5. a negative pressure pipe; 6. a boiling dryer; 7. an anti-blocking mechanism; 71. a drawing plate; 72. a handle; 8. discharging a hopper; 9. a hot air pipe; 10. an air heater; 11. and (3) screening.
Detailed Description
The present invention will be described more fully hereinafter with reference to the accompanying drawings, in which preferred embodiments are shown, for the purpose of illustrating the invention, but the scope of the invention is not limited to the specific embodiments shown.
Referring to fig. 1-3, a swing type granulation machine for medicine production comprises a base 1, a support 2 on the base 1 and a granulation mechanism 3 on the support 2, wherein a discharge pipe 4 is arranged at the lower end of the granulation mechanism 3, the lower end of the discharge pipe 4 is connected with one end of a negative pressure pipe 5, and the other end of the negative pressure pipe 5 is connected with a boiling dryer 6.
The swing type granulation machine of the embodiment directly sucks the medicine particles in the discharge pipe into the boiling dryer 6 through the negative pressure pipe 5, so that the medicine particles are dried in the boiling dryer, the conveying belt conveying and collecting processes are omitted, the problem of continuous blanking can be effectively solved, the problem of particle adhesion in the conveying process can be solved under the action of larger negative pressure wind force, and the production efficiency can be greatly improved.
In this embodiment, be equipped with in the discharging pipe 4 and prevent blockking up mechanism 7, can avoid appearing the jam phenomenon in the discharging pipe 4, can also realize controlling the velocity of flow problem of medicine in the discharging pipe 4 through preventing blockking up mechanism 7 moreover, can effectively avoid appearing the jam phenomenon in negative pressure pipe 5. The length of the discharging pipe 4 is not less than 30cm, the path of the medicine particles in the discharging pipe 4 is prolonged, and the blocking phenomenon in the negative pressure pipe 5 is avoided.
In this embodiment, the anti-blocking mechanism 7 includes a plurality of pull plates 71 made of light elastic material, when the negative pressure pipe 5 works, because of the negative pressure, the pull plates 71 incline towards the outlet of the discharging pipe 4, the inclination does not affect the falling of the drug particles in the discharging pipe 4, the inclination angle of the pull plates is 10 ° generally, and the two symmetrical sides of the plurality of pull plates 71 are arranged in a dislocation manner; in normal use, projections of the tail ends of the drawing plates 71 in the horizontal direction are overlapped, so that the route of the drug particles in the discharge pipe 4 is curved, thereby not only playing a role in preventing blockage, but also enabling the particle drugs to continuously roll in the falling process, being beneficial to further forming of the particles and weakening the adhesive force of the surfaces of the drug particles; when a blockage occurs, the drawing plate 71 closely below the blockage is pulled out, and after the blockage phenomenon contacts, the drawing plate 71 is reset. The end of the drawing plate 71, which is positioned at the discharging pipe 4, is provided with a handle 72, which is convenient for drawing the drawing plate 72. The distance between two adjacent drawing plates 71 was 4cm, and the drug particles smoothly dropped between the drawing plates 71.
In this embodiment, the negative pressure pipe 5 is made of plastic corrugated pipe, and the existence of the negative pressure pipe 5 does not affect the normal operation of the swing type granulator.
In this embodiment, the upper end of discharging pipe 4 is equipped with down hopper 8, and the intercommunication has hot-blast main 9 down hopper 8, and hot-blast main 9 is connected with air heater 10, under the combined action of negative pressure pipe 5 and hot-blast main 9, and hot-blast not only can not flow down the top of hopper and influence the granulation process of rocking granulator, but also can form hot-blast environment in hopper 8 down, discharging pipe 9 and negative pressure pipe 5, do benefit to the quick volatilization of medicine granule surface moisture, are favorable to eliminating the adhesive force on medicine granule surface, and then do benefit to the conveying process of medicine granule in negative pressure pipe 5 to go on smoothly. The screen 11 for the dropping of the medicine particles is arranged in the blanking hopper 8, and the screen 11 not only can play a role in controlling the dropping speed of the medicine particles, but also is convenient for reducing the aggregation of the medicine particles in the dropping process. The number of the screens 11 is two, the distance between the adjacent screens 11 is not less than 10cm, enough space is reserved, and the phenomenon that medicine particles are blocked between the screens 11 is avoided.

Claims (8)

1. The utility model provides a medicine production is with swaing granulation machine, includes the granulation mechanism on support and the support on base, granulation mechanism's lower extreme is provided with discharging pipe, its characterized in that: the lower end of the discharging pipe is connected with one end of a negative pressure pipe, and the other end of the negative pressure pipe is connected with the boiling dryer; an anti-blocking mechanism is arranged in the discharging pipe; the anti-blocking mechanism comprises a plurality of drawing plates made of light elastic materials, and when the negative pressure pipe works, the drawing plates incline to the outlet of the discharging pipe due to the existence of negative pressure, and the two symmetrical sides of the drawing plates are arranged in a staggered manner; in normal use, projections of the tail ends of the drawing plates in the horizontal direction are overlapped, so that the route of the drug particles in the discharge pipe is a curve; when the blockage occurs, the drawing plate which is clung to the lower part of the blockage is pulled out, and after the blockage phenomenon is solved, the drawing plate is reset.
2. The rocking granulation machine for pharmaceutical production according to claim 1, wherein: the pull plate is provided with a handle at the tail end of the discharging pipe.
3. The rocking granulation machine for pharmaceutical production according to claim 1, wherein: the distance between two adjacent drawing plates is 3-6 cm.
4. A rocking granulation machine for pharmaceutical production according to any one of claims 1 to 3, characterized in that: the negative pressure pipe is formed by a plastic corrugated pipe.
5. A rocking granulation machine for pharmaceutical production according to any one of claims 1 to 3, characterized in that: the upper end of discharging pipe is equipped with down the hopper, the intercommunication has the hot-blast main on the hopper down, and the hot-blast main is connected with the air heater.
6. The rocking granulation machine for pharmaceutical production according to claim 5, wherein: a screen for the drug particles to fall down is arranged in the discharging hopper.
7. The rocking granulation machine for pharmaceutical production according to claim 6, wherein: the number of the screens is 1-3, and when the number of the screens is more than one, the distance between the adjacent screens is not less than 10cm.
8. A rocking granulation machine for pharmaceutical production according to any one of claims 1 to 3, characterized in that: the length of the discharging pipe is not less than 30cm.
CN202210009053.4A 2022-01-06 2022-01-06 Swinging type granulation machine for medicine production Active CN114505013B (en)

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Application Number Priority Date Filing Date Title
CN202210009053.4A CN114505013B (en) 2022-01-06 2022-01-06 Swinging type granulation machine for medicine production

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Application Number Priority Date Filing Date Title
CN202210009053.4A CN114505013B (en) 2022-01-06 2022-01-06 Swinging type granulation machine for medicine production

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CN114505013B true CN114505013B (en) 2023-08-22

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