CN114441281B - Device for detecting tetracycline medicine residues in laboratory - Google Patents

Device for detecting tetracycline medicine residues in laboratory Download PDF

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Publication number
CN114441281B
CN114441281B CN202210108380.5A CN202210108380A CN114441281B CN 114441281 B CN114441281 B CN 114441281B CN 202210108380 A CN202210108380 A CN 202210108380A CN 114441281 B CN114441281 B CN 114441281B
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China
Prior art keywords
mounting groove
front side
laboratory
box
boxes
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CN202210108380.5A
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Chinese (zh)
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CN114441281A (en
Inventor
朱德伟
李蝶
蔡敏艳
康贻军
沈敏
张春
詹兴敏
李锐强
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Yancheng Tinghu District Dezerui Biotechnology Co ltd
Yancheng Teachers University
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Yancheng Tinghu District Dezerui Biotechnology Co ltd
Yancheng Teachers University
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Priority to CN202210108380.5A priority Critical patent/CN114441281B/en
Publication of CN114441281A publication Critical patent/CN114441281A/en
Priority to ZA2022/07939A priority patent/ZA202207939B/en
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Publication of CN114441281B publication Critical patent/CN114441281B/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B08CLEANING
    • B08BCLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B3/00Cleaning by methods involving the use or presence of liquid or steam
    • B08B3/04Cleaning involving contact with liquid
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01DMEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D21/00Measuring or testing not otherwise provided for
    • G01D21/02Measuring two or more variables by means not covered by a single other subclass
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/44Sample treatment involving radiation, e.g. heat
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7756Sensor type
    • G01N2021/7759Dipstick; Test strip

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a device for detecting tetracycline medicine residues in a laboratory, which comprises a shell, wherein two feeding boxes are arranged at the upper end of the shell, feeding holes are formed in the upper ends of the two feeding boxes, first blocking blocks are arranged on the two feeding holes, a mounting cavity is formed in the shell, a mounting box is arranged at the inner bottom of the mounting cavity, a mounting groove is formed in the front side of the mounting box, the front side of the mounting groove is communicated with the outside, and a rotary door is arranged at the front side of the mounting groove. The device is through setting up rabbling mechanism, can effectually guarantee to take the homogeneity degree that detects solution and detect reagent solution before detecting, avoids the inhomogeneous detection result that influences of solution, and the electro-magnet and the permanent magnet isotructure of setting can mix the operation fast, has improved the efficiency of detection, and wiper mechanism can clean the device after detecting the completion, avoids remaining residue to influence subsequent detection result.

Description

Device for detecting tetracycline medicine residues in laboratory
Technical Field
The invention relates to the technical field of detection of medicine residue in animal-derived foods, in particular to a device for detecting tetracycline medicine residue in a laboratory.
Background
The veterinary special medicine for tetracyclines, terramycin, aureomycin and tetracyclines has good antibacterial effect, is low in price, is widely applied to the field of livestock and aquatic organism cultivation at present, but is remained in animal tissues and livestock products due to unreasonable use, non-compliance of drug holidays and the like, and inevitably endangers human health after eating;
the main detection method of tetracycline medicine residues is liquid phase or liquid-mass combination and test paper detection, the liquid phase detection instrument is high in price, the test paper detection is simpler and more convenient than liquid phase detection, and the cost is lower, in the detection operation process of the test paper, the solution to be detected and the reagent need to be mixed manually, the operation is time-consuming and labor-consuming, the manual operation mixing effect is poor, and a certain amount of precipitation is easy to generate when the solution to be detected and the detection reagent are placed for a long time, so that the subsequent detection result is influenced.
Disclosure of Invention
The invention aims to solve the defects in the prior art, and provides a device for detecting tetracycline medicine residues in a laboratory.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
the utility model provides a laboratory detects remaining device of tetracycline, includes the casing, two feed boxes are installed to the upper end of casing, two the upper end of feed boxes all is equipped with the feed inlet, two all be equipped with first shutoff piece on the feed inlet, be equipped with the installation cavity in the casing, the installation box is installed to the interior bottom of installation cavity, the front side of installation box is equipped with the mounting groove, the front side of mounting groove is linked together with the external world, the revolving door is installed to the front side of mounting groove, two the discharging pipe is all installed to the lower extreme of feed box, two all install the solenoid valve on the discharging pipe, two the lower extreme of discharging pipe all installs a plurality of first bleeder pipes, and two corresponding first bleeder pipes extend to the mounting groove in and install the burette, two all be equipped with rabbling mechanism on the feed boxes, be equipped with mixing mechanism in the mounting groove;
the mixing mechanism comprises a moving block which is slidably connected in an installation groove, a placing block is arranged above the moving block, a placing frame is arranged on the placing block, a plurality of test tubes are arranged on the placing frame, two limiting grooves are formed in the upper end of the moving block, two connecting plates are fixedly connected to the lower ends of the placing block, the lower ends of the connecting plates are all extended into the corresponding limiting grooves, two connecting plates are respectively provided with a plurality of springs and the inner wall elastic connection of the corresponding limiting grooves at the left end and the right end of each connecting plate, a permanent magnet is fixedly connected to the right side of the placing block, and an electromagnet is embedded in the right inner wall of the installation groove.
Preferably, the stirring mechanism comprises two driving motors arranged at the upper ends of two feeding boxes, feeding cavities are formed in the two feeding boxes, and output shafts of the two driving motors extend to the feeding cavities and are provided with stirring assemblies.
Preferably, the upper end of casing is equipped with wiper mechanism, wiper mechanism is including installing the box in the casing upper end, the upper end of box is equipped with the water inlet, install the second sprue on the water inlet, install the water pump in the box, the main pipe is installed to the delivery port of water pump, two second branch pipes are installed to the upper end of main pipe, two all install the ring pipe in the feed box, two all install a plurality of shower nozzles on the ring pipe, two the one end that the main pipe was kept away from to the second branch pipe links to each other with the ring pipe that corresponds respectively.
Preferably, the upper end of the moving block is provided with a storage groove, a storage box is connected in a sliding manner in the storage groove, and a handle is arranged on the front side of the storage box.
Preferably, the upper end of the placing block is provided with a plurality of placing grooves, and the lower end of each test tube is positioned in the corresponding placing groove.
Preferably, a plurality of through grooves are formed in the inner bottom of each placing groove, and rubber pads are mounted on the inner walls of the placing grooves.
Preferably, two handles are arranged on the front side of the moving block, and anti-slip rubber is sleeved on each handle.
Preferably, a temperature and humidity sensor is installed at the inner top of the installation groove, and a plurality of heating pipes are embedded in the inner wall of the installation box.
Preferably, two electric hydraulic telescopic rods are installed on the inner wall of the rear side of the installation groove, the telescopic ends of the two electric hydraulic telescopic rods are fixedly connected with a baffle together, and a rubber pad is installed at the lower end of the baffle.
Compared with the prior art, the device has the advantages that:
1. according to the invention, through arranging the structures of the feeding box, the electromagnetic valve, the stirring mechanism, the discharging pipe, the first branch pipe and the like, the feeding box can stir the detection objects and the reagents, so that the two solutions are in a relatively uniform state, the detection effect is improved, the detection objects and the reagents can be guided into the plurality of test tubes for vibration mixing, and the operation is convenient and quick.
2. According to the invention, the cleaning mechanism is arranged, a certain amount of materials are inevitably adhered to the inner wall of the feeding box after the processing is finished, the feeding box can be cleaned through the structures such as the water pump and the annular pipe, the cleaned water body can be led into the storage box, the collection is convenient, the labor capacity of staff is reduced, and the accuracy of a subsequent test is ensured.
3. According to the invention, the temperature and humidity state in the installation box can be detected in real time by arranging the structures such as the temperature and humidity sensor and the heating pipe, and the temperature and humidity state can be regulated by matching with the heating pipe according to the detection requirement, so that the test can be accurately and efficiently carried out.
Drawings
FIG. 1 is a schematic diagram of a laboratory device for detecting tetracycline drug residues;
FIG. 2 is a cross-sectional view of FIG. 1;
FIG. 3 is an enlarged view of the structure of FIG. 2 at A;
FIG. 4 is a cross-sectional view of FIG. 3;
fig. 5 is an enlarged view of the structure at B in fig. 4.
In the figure: 1 casing, 2 revolving door, 3 feeding boxes, 4 boxes, 5 driving motor, 6 first chock blocks, 7 second chock blocks, 8 discharging pipes, 9 first lateral pipes, 10 water pumps, 11 main pipes, 12 second lateral pipes, 13 mounting boxes, 14 droppers, 15 moving blocks, 16 storage boxes, 17 placing racks, 18 baffle plates, 19 electric hydraulic telescopic rods, 20 annular pipes, 21 stirring components, 22 heating pipes, 23 temperature and humidity sensors, 24 permanent magnets, 25 electromagnets, 26 connecting plates, 27 limiting grooves, 28 springs, 29 placing blocks, 30 through grooves and 31 electromagnetic valves.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments.
Referring to fig. 1-5, a device for detecting tetracycline medicine residues in a laboratory comprises a shell 1, two feeding boxes 3 are installed at the upper ends of the shell 1, feeding inlets are formed in the upper ends of the two feeding boxes 3, first blocking blocks 6 are arranged on the two feeding inlets, the two feeding boxes 3 are respectively used for guiding in solution to be detected and mixed reagent for detection, an installation cavity is formed in the shell 1, an installation box 13 is installed at the inner bottom of the installation cavity, an installation groove is formed in the front side of the installation box 13, the front side of the installation groove is communicated with the outside, a rotary door 2 is installed at the front side of the installation groove, discharging pipes 8 are installed at the lower ends of the two feeding boxes 3, electromagnetic valves 31 are installed on the two discharging pipes 8, the electromagnetic valves 31 are opened when being electrified, a plurality of first branched pipes 9 are installed at the lower ends of the two corresponding branched pipes 9 extend into the installation groove and are installed with droppers 14, the solution and the reagent can be divided into a plurality of parts, and drop into corresponding droppers 14 and the corresponding droppers together into corresponding droppers for subsequent test tubes, and subsequent test experiments are convenient to carry out;
the mounting groove is internally provided with a mixing mechanism, the mixing mechanism comprises a moving block 15 which is slidably connected in the mounting groove, a placing block 29 is arranged above the moving block 15, a placing rack 17 is arranged on the placing block 29, a plurality of test tubes are arranged on the placing rack 17, the placing rack 17 is a traditional rack body for placing the test tubes, the upper end of the moving block 15 is provided with two limiting grooves 27, the lower end of the placing block 29 is fixedly connected with two connecting plates 26, the lower ends of the two connecting plates 26 are all extended into the corresponding limiting grooves 27, the left end and the right end of the two connecting plates 26 are all provided with a plurality of springs 28 which are elastically connected with the inner walls of the corresponding limiting grooves 27, the right side of the placing block 29 is fixedly connected with a permanent magnet 24, an electromagnet 25 is embedded in the inner wall on the right side of the mounting groove, and after the electromagnet 25 is electrified, the magnetic poles of the electromagnet 25 and the permanent magnet 24 are opposite can be continuously changed, and then the permanent magnet 24 is continuously attracted or repelled.
Wherein, stirring mechanisms are arranged on the two feeding boxes 3, each stirring mechanism comprises two driving motors 5 arranged at the upper ends of the two feeding boxes 3, feeding cavities are arranged in the two feeding boxes 3, the output shafts of the two driving motors 5 extend to the feeding cavities and are provided with stirring assemblies 21, and solutions in the corresponding feeding boxes 3 can be stirred by starting the two driving motors 5;
wherein, the upper end of casing 1 is equipped with wiper mechanism, wiper mechanism is including installing the box 4 in casing 1 upper end, be used for placing the water in the box 4, the upper end of box 4 is equipped with the water inlet, install second sprue 7 on the water inlet, install water pump 10 in the box 4, after the water pump 10 starts, can be with the water in the box 4 through trunk line 11 and the leading-in annular pipe 20 of second branch pipe 12, clean feeding box 3, trunk line 11 is installed to the delivery port of water pump 10, two second branch pipes 12 are installed to the upper end of trunk line 11, all install annular pipe 20 in two feeding boxes 3, all install a plurality of shower nozzles on two annular pipes 20, the one end that trunk line 11 was kept away from to two second branch pipes 12 links to each other with corresponding annular pipe 20 respectively.
Wherein, the upper end of movable block 15 is equipped with the storage tank, sliding connection has receiver 16 in the storage tank, the handle is installed to the front side of receiver 16, the upper end of placing block 29 is equipped with a plurality of standing grooves, the lower extreme of every test tube is located corresponding standing groove, the interior bottom of every standing groove all is equipped with a plurality of logical grooves 30, the rubber pad is installed to the inner wall of standing groove, two handles are installed to the front side that improves test tube movable block 15, all the cover is equipped with anti-skidding rubber on two handles, temperature and humidity sensor 23 is installed at the interior top of mounting groove, temperature and humidity sensor 23 can the inside humiture of real-time supervision mounting groove, the inner wall of mounting box 13 inlays and is equipped with a plurality of heating pipes 22, through temperature and humidity sensor 23 and heating pipe 22 matched with, can adjust the mounting groove internal environment, the test of being convenient for is quick accurate.
Wherein, two electric hydraulic telescoping rods 19 are installed to the rear side inner wall of mounting groove, and the common fixedly connected with baffle 18 of flexible end of two electric hydraulic telescoping rods 19, the rubber pad is installed to the lower extreme of baffle 18, starts the upper end that two electric hydraulic telescoping rods 19 can drive baffle 18 test tube, when can avoid vibrations, mixed liquid spill.
When the liquid storage box is used, two first blocking blocks 6 are opened, the solution to be detected and the detection liquid are actually led into two feeding boxes 3 respectively, a driving motor 5 is started, a stirring assembly 21 stirs the liquid in the feeding boxes 3, after stirring for a period of time, an electromagnetic valve 31 is started for a certain time, two equal amounts of the solution are led into a plurality of test tubes through a plurality of first branch pipes 9 and corresponding drip tubes 14, then an electromagnet 25 is electrified, so that one end magnetic pole of the electromagnet 25 relative to a permanent magnet 24 is continuously changed, the permanent magnet 24 is continuously attracted or repelled, a placing block 29 is driven to vibrate in a left-right reciprocating manner, namely, the solution in the test tubes starts to be mixed, if the liquid is afraid of being mixed, two electro-hydraulic telescopic rods 19 can be started to drive a baffle 18 to the upper ends of the plurality of test tubes, the liquid can be effectively prevented from shaking out, after the mixing is completed, a rotating door 2 is opened, the moving block 15 is pulled out, the detected test paper is put into the corresponding test tubes for detection, after the detection is completed, a test tube 10 is taken out, the test tube is led into the two feeding boxes 3, the motor is led into the two main pipelines, the two main pipelines 3 are continuously changed, the two test tubes are driven to be conveniently and the two test tubes are conveniently placed into the main pipelines 16, and the storage boxes are conveniently and the storage box is cleaned through the two main pipelines 11 and the two test tubes are conveniently and the storage box is opened, and the storage box is 16 is convenient and is opened, and the storage box is 16 and is convenient and easy to be opened and easy to store and convenient and easy to be 16 and convenient and easy to use;
the device is through setting up rabbling mechanism, can effectually guarantee to take the homogeneity degree that detects solution and detect reagent solution before detecting, avoids solution inhomogeneous to influence testing result, and the electro-magnet 25 and the permanent magnet 24 isotructure of setting can carry out the mixed operation fast, has improved the efficiency of detection, and wiper mechanism can clean the device after detecting the completion, avoids remaining residue to influence subsequent testing result.
The foregoing is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical scheme of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.

Claims (6)

1. The utility model provides a device that laboratory detected tetracycline medicine remained, includes casing (1), its characterized in that, two feed boxes (3) are installed to the upper end of casing (1), two all be equipped with the feed inlet on feed boxes (3), two all be equipped with first sprue (6) on the feed inlet, be equipped with the installation cavity in casing (1), install mounting box (13) in the interior bottom of installation cavity, the front side of mounting box (13) is equipped with the mounting groove, the front side of mounting groove is linked together with the external world, revolving door (2) are installed to the front side of mounting groove, two discharge pipe (8) are all installed to the lower extreme of feed boxes (3), two all install solenoid valve (31) on discharge pipe (8), two all install a plurality of first lateral pipe (9) on the lower extreme of discharge pipe (8), two corresponding first lateral pipe (9) extend to the mounting groove in and install drip tube (14), two are equipped with on feed boxes (3) and mix in the mounting groove, the mechanism is equipped with in the mounting groove;
the mixing mechanism comprises a moving block (15) which is slidably connected in an installation groove, a placing block (29) is arranged above the moving block (15), a placing rack (17) is arranged on the placing block (29), a plurality of test tubes are arranged on the placing rack (17), two limit grooves (27) are formed in the upper end of the moving block (15), two connecting plates (26) are fixedly connected to the lower end of the placing block (29), the lower ends of the two connecting plates (26) extend into the corresponding limit grooves (27), a plurality of springs (28) are arranged at the left end and the right end of the two connecting plates (26) and are elastically connected with the inner walls of the corresponding limit grooves (27), permanent magnets (24) are fixedly connected to the right side of the placing block (29), and electromagnets (25) are embedded in the right inner walls of the installation grooves; the stirring mechanism comprises two driving motors (5) arranged at the upper ends of two feeding boxes (3), feeding cavities are arranged in the two feeding boxes (3), and output shafts of the two driving motors (5) extend to the feeding cavities and are provided with stirring assemblies (21); the upper end of the shell (1) is provided with a cleaning mechanism, the cleaning mechanism comprises a box body (4) arranged at the upper end of the shell (1), the upper end of the box body (4) is provided with a water inlet, a second blocking block (7) is arranged on the water inlet, a water pump (10) is arranged in the box body (4), a main pipeline (11) is arranged at the water outlet of the water pump (10), two second branch pipelines (12) are arranged at the upper end of the main pipeline (11), annular pipes (20) are arranged in the feeding boxes (3), a plurality of spray heads are arranged on the two annular pipes (20), and one ends, far away from the main pipeline (11), of the two second branch pipelines (12) are respectively connected with the corresponding annular pipes (20); two electric hydraulic telescopic rods (19) are arranged on the inner wall of the rear side of the mounting groove, the telescopic ends of the two electric hydraulic telescopic rods (19) are fixedly connected with a baffle plate (18) together, and a rubber pad is arranged at the lower end of the baffle plate (18).
2. The device for detecting tetracycline drug residues in a laboratory according to claim 1, wherein a storage groove is formed in the upper end of the moving block (15), a storage box (16) is slidably connected in the storage groove, and a handle is mounted on the front side of the storage box (16).
3. A laboratory device for detecting tetracycline drug residues according to claim 2, characterized in that said placement block (29) is provided with a plurality of placement slots at its upper end, and each of said test tubes is provided with a lower end located in a corresponding placement slot.
4. A laboratory device for detecting tetracycline drug residues according to claim 3, wherein a plurality of through slots (30) are provided in the inner bottom of each of said holding slots, and rubber pads are mounted on the inner walls of said holding slots.
5. The device for detecting tetracycline drug residues in a laboratory according to claim 1, wherein two handles are mounted on the front side of the movable block (15), and anti-slip rubber is sleeved on each of the two handles.
6. The device for detecting tetracycline drug residues in a laboratory of claim 4, wherein a temperature and humidity sensor (23) is installed at the inner top of the installation groove, and a plurality of heating pipes (22) are embedded in the inner wall of the installation box (13).
CN202210108380.5A 2022-01-28 2022-01-28 Device for detecting tetracycline medicine residues in laboratory Active CN114441281B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN202210108380.5A CN114441281B (en) 2022-01-28 2022-01-28 Device for detecting tetracycline medicine residues in laboratory
ZA2022/07939A ZA202207939B (en) 2022-01-28 2022-07-18 Device for detecting tetracycline medicine residue in laboratory

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210108380.5A CN114441281B (en) 2022-01-28 2022-01-28 Device for detecting tetracycline medicine residues in laboratory

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CN114441281B true CN114441281B (en) 2024-01-02

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CN113462551A (en) * 2021-07-06 2021-10-01 厦门啸骨贸易有限公司 Mixing device capable of controlling temperature and used for biological cell culture
CN214781770U (en) * 2021-07-09 2021-11-19 哈尔滨合卓生物科技有限公司 Vibration device for DNA methylation test

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