CN114432569B - Surface treatment method and equipment for interventional catheter - Google Patents
Surface treatment method and equipment for interventional catheter Download PDFInfo
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- CN114432569B CN114432569B CN202111671884.XA CN202111671884A CN114432569B CN 114432569 B CN114432569 B CN 114432569B CN 202111671884 A CN202111671884 A CN 202111671884A CN 114432569 B CN114432569 B CN 114432569B
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- interventional catheter
- catheter
- vacuum chamber
- interventional
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
- A61M2025/0046—Coatings for improving slidability
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E30/00—Energy generation of nuclear origin
- Y02E30/10—Nuclear fusion reactors
Abstract
The application discloses a surface treatment method of an interventional catheter, which comprises the following steps: s100, pretreatment: the application can make the intervention catheter perform wrapped regional treatment when performing surface treatment through the fixing component, so as to avoid uneven surface treatment caused by the intervention catheter being blocked by the clamping device; then the rotating frame can clamp the intervention catheter and drive the intervention catheter to rotate around the center of the vacuum chamber in the vacuum chamber so as to enable the whole intervention catheter to pass through the annular treatment chamber; then the lifting component is inserted into the solution corresponding to the current interventional catheter position in the multiple solutions with the interventional catheter; the stent assembly is then repositioned to the different solutions aligned with the interventional catheter.
Description
Technical Field
The application relates to the technical field of medical instruments, in particular to a surface treatment method and equipment of an interventional catheter.
Background
Lubricity is one of important properties of intravascular interventional catheters, and when the catheter enters and exits a blood vessel and moves in the blood vessel, high lubricity can inhibit adhesion of macromolecules in blood such as plasma proteins, platelets and the like on the surface of materials, reduce damage to the wall of the blood vessel and blood cells, lighten disturbance to blood laminar flow, and avoid coagulation reaction.
In the prior art, there are various operation modes for surface treatment of an interventional catheter, wherein an important step is that the interventional catheter is placed in a sample chamber of a plasma generator during treatment, and then is subjected to plasma treatment after gas is introduced, for example, in the patent of application number 202110964059.2, a surface treatment device for an anti-off-load medical cardiovascular medium balloon catheter is disclosed, the surface of the catheter is subjected to pretreatment, a motor rotates with a turntable, then an elliptical groove controls the movement of a pull rod to stretch a rope B, further two connecting rods move in a movable hole and simultaneously deflect with two clamping rings until the cardiovascular balloon catheter is firmly clamped, then the motor is closed, a foot pedal is stepped down to enable the cardiovascular balloon catheter to move downwards with a cross rod, a rope A moves with an L-shaped clamping rod in the process of moving the cross rod until the L-shaped clamping rod is clamped with the L-shaped groove, and then square blocks move out of the square groove, and then people can rotate a treatment disc while carrying out surface treatment on the cardiovascular balloon catheter, namely, the cardiovascular balloon catheter can be firmly clamped, and the cardiovascular surface can be firmly clamped while working.
However, this operation has a limitation in the case of uneven surface treatment, for example, the interventional catheter is directly driven to rotate around the turntable by the turntable when the interventional catheter is subjected to surface treatment, but the surface of the interventional catheter is limited by the clamping device, so that the surface of the catheter is easy to have a shielding area, and the uneven surface treatment of the catheter is caused.
Therefore, the surface treatment equipment of the interventional catheter in the prior art cannot solve the problem that the surface treatment is uneven due to the fact that the catheter is shielded by the clamping device when the surface treatment is carried out on the catheter.
Disclosure of Invention
The application aims to provide a surface treatment method and equipment for an interventional catheter, which are used for solving the technical problem that in the prior art, when the catheter is subjected to surface treatment, the surface treatment is uneven due to the fact that the catheter is shielded by a clamping device.
In order to solve the technical problems, the application specifically provides the following technical scheme,
a method of surface treatment of an interventional catheter, comprising the steps of:
s100, pretreatment: placing the intervention catheter into a sample chamber of a plasma generator, and carrying out wrapped plasma treatment on the side wall of the intervention catheter after introducing gas;
s200, modification treatment: immersing the pretreated interventional catheter in the grafting modification solution for a certain time, taking out the interventional catheter, and sequentially carrying out the surface cleaning and immersing treatment and the surface drying treatment of the interventional catheter;
s300, coating: coating a coupling agent and a coating solution on the surface of the interventional catheter obtained in the step S200 in sequence and curing;
s400, post-processing: immersing the interventional catheter obtained in the step S300 into strong ammonia water, taking out and drying.
In order to solve the above technical problem, the present application further provides a treatment device for a surface treatment method of an interventional catheter, where both the step S100 and the step S200 are performed in the treatment device:
the processing device comprises
A vacuum chamber capable of storing a plurality of solutions for soaking at the bottom;
the adjusting mechanism is connected to the top of the vacuum chamber in a penetrating way;
the rotating frame is connected to the central position inside the vacuum chamber;
the adjusting mechanism comprises a lifting assembly, an expanding assembly and a fixing assembly;
the lifting assembly is connected to the top of the vacuum chamber in a sealing way, one end of the lifting assembly penetrates through the vacuum chamber and extends to the outer side, the other end of the lifting assembly is positioned in the vacuum chamber and connected with the expansion assembly, the side wall of the expansion assembly is connected with the lifting assembly, and the fixing assembly is connected to the side wall of the expansion assembly;
the fixing component can fix the position of the interventional catheter and is provided with at least one annular treatment chamber on the side wall of the interventional catheter; the rotating frame is used for clamping the intervention catheter and driving the intervention catheter to rotate around the center of the vacuum chamber in the vacuum chamber so as to enable the whole intervention catheter to pass through the annular treatment chamber; the lifting assembly can insert the interventional catheter into a solution corresponding to the current interventional catheter position in a plurality of solutions; the expansion assembly is capable of changing the position of different solutions aligned by the interventional catheter.
As a preferable scheme of the application, the inner wall of the bottom of the vacuum chamber is provided with a plurality of liquid storage channels, and the inner side wall of the vacuum chamber is connected with a target sleeve;
the lifting assembly comprises a sealing isolation sleeve penetrating through the top of the vacuum chamber, the side wall of the sealing isolation sleeve is in sealing connection with the vacuum chamber, an extension sleeve is connected in the sealing isolation sleeve, one end, close to the vacuum chamber, of the extension sleeve is connected with the expansion assembly, and the extension sleeve can axially move in the sealing isolation sleeve;
the expansion assembly comprises a limiting sleeve connected with one end of the sealing isolation sleeve positioned in the vacuum chamber, two ends of the limiting sleeve are connected with an expansion sleeve, and the expansion sleeve can axially move in the limiting sleeve to change the position of the interventional catheter;
the fixed subassembly includes a plurality of fixed point clamps and at least one half arc cover, and is a plurality of the fixed point clamp sets up along two expansion cover lateral wall, and a plurality of the fixed point clamp combination forms annular structure, the fixed point clamp is used for fixed restriction to intervene the position of pipe, half arc cover is connected the lateral wall of restriction cover, half arc cover can hug closely the target cover with the combination form non-confined parcel ring.
As a preferable scheme of the application, the rotating frame comprises a rotating disc arranged at the inner center position of a vacuum chamber, the side wall of the rotating disc is rotationally connected with a sliding column, the side wall of the sliding column is sleeved with a pull-back spring connected with the rotating disc, the sliding column can be driven to reset by the pull-back spring after rotating with the rotating disc, one end of the sliding column far away from the rotating disc is connected with a plurality of holding pieces, one side of the holding piece far away from the sliding column is provided with a plurality of clamping pieces rotationally connected with the sliding column, and the holding pieces and the clamping pieces are correspondingly combined one by one to form a clamp for clamping an interventional catheter.
As a preferable scheme of the application, the expansion sleeve comprises a sideways sliding sleeve which is connected in the limiting sleeve in a sliding way, one end of the sideways sliding sleeve, which is far away from the limiting sleeve, is connected with an end sliding sleeve, and the end sliding sleeve can axially slide in the sideways sliding sleeve.
As a preferable scheme of the application, the side wall of the limiting sleeve is provided with a friction strip, the side wall of the friction strip is provided with a pipe body rubbing strip, and the friction strip and the pipe body rubbing strip can be mutually adhered and clamp the intervention catheter between the two;
the limiting sleeve is internally provided with a pulling column connected with the pipe body rubbing strip, and the pulling column can axially move in the sealing isolation sleeve to reciprocally pull the pipe body rubbing strip to rub the intervention catheter.
As a preferable scheme of the application, a pair of expansion sleeves are arranged at two ends of the wrapping ring, the expansion sleeves are respectively connected with the half arc sleeve and the target sleeve in one-to-one correspondence, and the expansion sleeves can push the fixing piece and the clamping piece to expand.
As a preferred solution of the application, elastic clamping blocks are arranged in the fixed point clamps, and the elastic clamping blocks can be pushed by the fixing sheets and the clamping sheets to open and release the limited interventional catheter.
As a preferable scheme of the application, an included angle is arranged between the elastic clamping block and the lateral sliding sleeve, and the included angle is in the range of 0-90 degrees.
As a preferable scheme of the application, the thickness of the two ends of the expanding sleeve is not larger than the thickness of the center of the expanding sleeve.
Compared with the prior art, the application has the following beneficial effects,
the application can make the interventional catheter perform wrapped regional treatment when performing surface treatment through the fixing component, so as to avoid uneven surface treatment caused by the interventional catheter being shielded by the clamping device; then the rotating frame can clamp the intervention catheter and drive the intervention catheter to rotate around the center of the vacuum chamber in the vacuum chamber so as to enable the whole intervention catheter to pass through the annular treatment chamber; then the lifting component is inserted into the solution corresponding to the current interventional catheter position in the multiple solutions with the interventional catheter; the stent assembly is then repositioned to the different solutions aligned with the interventional catheter.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. It will be apparent to those of ordinary skill in the art that the drawings in the following description are exemplary only and that other implementations can be obtained from the extensions of the drawings provided without inventive effort.
FIG. 1 is a schematic diagram of the overall structure of an embodiment of the present application;
FIG. 2 is a schematic view of a vacuum chamber according to an embodiment of the present application;
FIG. 3 is a schematic view of a structure of a lateral sliding sleeve according to an embodiment of the present application when the lateral sliding sleeve is not opened;
FIG. 4 is a schematic view of a structure of the lateral sliding sleeve according to an embodiment of the present application when the lateral sliding sleeve is opened;
FIG. 5 is a schematic view of a structure of a rubbing strip for a tube body according to an embodiment of the present application;
FIG. 6 is a top view of a sliding column according to an embodiment of the present application;
FIG. 7 is a flow chart of a surface treatment of an intermediary catheter in an embodiment of the application.
Reference numerals in the drawings are respectively indicated as follows,
1-a vacuum chamber; 2-an adjusting mechanism; 3-rotating frame; 4-lifting assembly; 5-an expansion assembly; 6-fixing the assembly;
11-a liquid storage channel; 12-target sleeve; 31-rotating a disc; 32-sliding columns; 33-pull-back spring; 34-holding pieces; 35-clamping pieces; 41-sealing the insulating sleeve; 42-extending sleeve;
51-a limiting sleeve; 52-expanding sleeve;
61-a fixed point clip; 62-half arc sleeve; 63-wrapping the ring;
511-friction bars; 512-rubbing strips on the tube body; 513-pulling the column; 521-rolling sliding sleeve; 522-end sliding sleeve; 611-elastic clamp blocks; 631-expanding the sleeve.
Detailed Description
The following description of the embodiments of the present application will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present application, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.
As shown in fig. 7, the present application provides a surface treatment method of an interventional catheter, comprising the steps of:
s100, pretreatment: placing the intervention catheter into a sample chamber of a plasma generator, and carrying out wrapped plasma treatment on the side wall of the intervention catheter after introducing gas, wherein the discharge power is 10W to 310W, and the treatment time is 1min to 5min;
s200, modification treatment: soaking the pretreated intervention catheter in a grafting modification solution for a certain time, taking out the intervention catheter, and sequentially carrying out the surface cleaning and soaking treatment and the surface drying treatment of the intervention catheter, wherein the grafting modification solution is a solution composed of glycidyl methacrylate and a first organic solvent, the mass percentage concentration of the glycidyl methacrylate in the solution is 5-95%, the temperature of the grafting modification treatment is 30-90 ℃, the soaking time of the intervention catheter is 2-24 hours, the drying temperature of the drying treatment is 65-75 ℃, and the drying time is 10-14 hours;
s300, coating: coating a coupling agent and a coating solution onto the surface of the interventional catheter obtained in the step S200 in sequence and curing, wherein the coupling agent (for example, epoxy-containing siloxane) is coated to increase the adhesive force of the coating solution;
s400, post-processing: immersing the interventional catheter obtained in the step S300 into strong ammonia water, taking out and drying.
In this embodiment, compared with the prior art, the method can perform wrapped-type plasma treatment on the side wall of the interventional catheter during the pretreatment (that is, in the case of normal treatment, the interventional catheter is subjected to the action of performing the treatment on the interventional catheter outside the catheter in a synchronized and regional surrounding manner during the normal treatment).
The specific treatment of the surface treatment method of the interventional catheter is as follows: the surface treatment efficiency is mainly increased by the action of the wrapped plasma treatment, the adhesion force is increased on the surface of the catheter subjected to the surface treatment by the coupling agent, and other stages are the same as the prior art.
Example 2:
as shown in fig. 1, a processing apparatus for a surface treatment method, in which steps S100 and S200 are both performed:
the processing device comprises
A vacuum chamber 1 capable of storing a plurality of solutions for soaking at the bottom;
the adjusting mechanism 2 is connected to the top of the vacuum chamber 1 in a penetrating way;
a rotating frame 3 connected to the central position inside the vacuum chamber 1;
wherein, the adjusting mechanism 2 comprises a lifting component 4, an expanding component 5 and a fixing component 6;
the lifting assembly 4 is connected to the top of the vacuum chamber 1 in a sealing way, one end of the lifting assembly 4 penetrates through the vacuum chamber 1 and extends to the outer side, the other end of the lifting assembly 4 is positioned in the vacuum chamber 1 and is connected with the expansion assembly 5, the side wall of the expansion assembly 5 is connected with the lifting assembly 4, and the fixing assembly 6 is connected to the side wall of the expansion assembly 5;
the fixing assembly 6 is capable of fixing the position of the interventional catheter and providing at least one annular treatment chamber on the side wall of the interventional catheter; the rotating frame 3 is used for clamping the interventional catheter and driving the interventional catheter to rotate around the center of the vacuum chamber 1 in the vacuum chamber 1 so as to enable the whole interventional catheter to pass through the annular treatment chamber; the lifting assembly 4 can insert the interventional catheter into a solution corresponding to the current interventional catheter position in a plurality of solutions; the expansion assembly 5 is capable of changing the position of different solutions that the interventional catheter is aligned with.
The treatment equipment can enable the interventional catheter to carry out wrapped regional treatment when carrying out surface treatment through the fixing component 6, so as to avoid uneven surface treatment caused by the interventional catheter being shielded by the clamping device, and when the treatment equipment is implemented, the fixing component 6 can fix the position of the interventional catheter and set at least one annular treatment chamber on the side wall of the interventional catheter; the rotating frame 3 clamps the interventional catheter and drives the interventional catheter to rotate around the center of the vacuum chamber 1 in the vacuum chamber 1 so as to enable the whole interventional catheter to pass through the annular processing chamber; then the lifting assembly 4 is inserted into the solution corresponding to the current interventional catheter position in the multiple solutions with the interventional catheter; the stent assembly 5 is then repositioned to the different solutions to which the interventional catheter is aligned.
As shown in fig. 1 and 2, a plurality of liquid storage channels 11 are arranged on the inner wall of the bottom of the vacuum chamber 1, and a target sleeve 12 is connected to the inner side wall of the vacuum chamber 1;
the lifting assembly 4 comprises a sealing isolation sleeve 41 penetrating through the top of the vacuum chamber 1, the side wall of the sealing isolation sleeve 41 is in sealing connection with the vacuum chamber 1, an extension sleeve 42 is connected in the sealing isolation sleeve 41, one end, close to the vacuum chamber 1, of the extension sleeve 42 is connected with the expansion assembly 5, and the extension sleeve 42 can axially move in the sealing isolation sleeve 41;
the expansion assembly 5 comprises a limiting sleeve 51 connected with one end of the sealing isolation sleeve 41 positioned in the vacuum chamber 1, two ends of the limiting sleeve 51 are connected with an expansion sleeve 52, and the expansion sleeve 52 can axially move in the limiting sleeve 51 to change the position of the interventional catheter;
the fixing assembly 6 comprises a plurality of fixing point clips 61 and at least one half-arc sleeve 62, the plurality of fixing point clips 61 are arranged along the side walls of the two expansion sleeves 52, the plurality of fixing point clips 61 are combined to form an annular structure, the fixing point clips 61 are used for fixing the position for limiting the interventional catheter, the half-arc sleeve 62 is connected to the side wall of the limiting sleeve 51, and the half-arc sleeve 62 can be tightly attached to the target sleeve 12 to form an unsealed wrapping ring 63.
In order to realize the action of enabling the interventional catheter to carry out wrapped regional treatment when carrying out surface treatment, during specific work, the interventional catheter is directly clamped between a plurality of fixed point clamps 61, meanwhile, the interventional catheter is positioned in a wrapped ring 63 (the interventional catheter is first disconnected), once the interventional catheter is driven by a rotating frame 3 to rotate around the rotating frame 3, the interventional catheter can slide along the axis of the wrapped ring 63, in the process, the wrapped ring 63 (the surface pretreatment in the prior art is carried out by the principle of arc evaporation plating), the target sleeve 12 can be evaporated) can wrap and cover more surface area of the interventional catheter, so that the pretreatment effect of the interventional catheter is better.
While the interventional catheter needs to be modified after the pretreatment is completed, that is, the interventional catheter is soaked by different solutions, the method can also be carried out in the vacuum chamber 1 (that is, the vacuum chamber 1 subjected to the pretreatment is vacuumized to ensure that the drying effect is better, that is, the vacuum drying is realized), after the working environment is treated, the extension sleeve 42 can be axially moved in the sealing and isolating sleeve 41 to enable the interventional catheter to be immersed in the first solution, then the interventional catheter is lifted, the expansion sleeve 52 can be axially moved in the limiting sleeve 51 to change the position of the interventional catheter, so that the interventional catheter is changed from being aligned with the storage channel 11 storing the first solution to being aligned with the storage channel 11 storing the second solution, and then the interventional catheter is put down to the second solution.
As shown in fig. 1 and 6, the rotating frame 3 includes a rotating disc 31 disposed at a central position inside the vacuum chamber 1, a sliding column 32 is rotatably connected to a side wall of the rotating disc 31, a pull-back spring 33 connected to the rotating disc 31 is sleeved on a side wall of the sliding column 32, the sliding column 32 can be driven to reset by the pull-back spring 33 after rotating with the rotating disc 31, one end of the sliding column 32 far away from the rotating disc 31 is connected with a plurality of holding pieces 34, one side of the holding piece 34 far away from the sliding column 32 is provided with a plurality of clamping pieces 35 rotatably connected with the sliding column 32, and the holding pieces 34 and the clamping pieces 35 are combined in a one-to-one correspondence manner to form a clamp for clamping an interventional catheter.
The specific structure of the pull-back spring 33 is shown in fig. 1, and the pull-back spring has a large end and a small end, so that the elastic resetting capability and the deflection capability are not affected.
When the device specifically works, the rotating disc 31 is driven to rotate through the external driver, then the rotating disc 31 drives the clamp holders to rotate together through the sliding columns 32, and the clamping force applied to the interventional catheter by the clamp holders is multiple because the clamp holders 34 and 35 are all arranged, so that the clamp holders can be continuously clamped even if one clamp holder is loose and the other clamp holders are loose, the purpose of stabilizing the end part of the interventional catheter can be achieved, and the end part of the interventional catheter cannot be bent and tilted in the moving process.
The expansion sleeve 52 comprises a roll-over sliding sleeve 521 slidably connected within the constraining sleeve 51, and an end of the roll-over sliding sleeve 521 remote from the constraining sleeve 51 is connected with an end sliding sleeve 522, the end sliding sleeve 522 being capable of sliding axially within the roll-over sliding sleeve 521.
The expansion sleeve 52 can be directly injected into the limiting sleeve 51 to enable the sideslip sliding sleeve 521 to slide out of the limiting sleeve 51 during expansion, and the end sliding sleeve 522 only needs to slide out of the sideslip sliding sleeve 521, namely, the state shown in fig. 3 is moved to the state shown in fig. 4.
As shown in fig. 1 and 5, a friction strip 511 is mounted on the side wall of the limiting sleeve 51, a tube rubbing strip 512 is arranged on the side wall of the friction strip 511, and the friction strip 511 and the tube rubbing strip 512 can be mutually adhered and clamp an interventional catheter between the two;
a pulling column 513 connected to the tube kneading bar 512 is provided in the restricting housing 51, and the pulling column 513 is axially movable in the sealing insulating housing 41 to reciprocally pull the tube kneading bar 512 to rub the interventional catheter.
As shown in fig. 5, a sliding slot is provided on the side wall of the limiting sleeve 51 corresponding to the tube rubbing strip 512, and an insulating film can be mounted on the pulling column 513 to prevent gas from entering the vacuum chamber 1 through the sliding slot.
The catheter is easily shielded when the catheter slides, so that the small motor can be driven by the driver to drive the pulling column 513 to axially move in the sealing isolation sleeve 41 so as to reciprocally pull the tube rubbing strip 512 to rub the interventional catheter, and then the rubbed interventional catheter can rotate to enable the whole surface of the interventional catheter to fully accept pretreatment.
A pair of expanding sleeves 631 are provided at both ends of the wrapping ring 63, the pair of expanding sleeves 631 are respectively connected with the half arc sleeve 62 and the target sleeve 12 in one-to-one correspondence, and the pair of expanding sleeves 631 can push the holding piece 34 and the clamping piece 35 to expand.
This is to prevent the holding piece 34 and the holding piece 35 from blocking the catheter when the catheter enters the wrapping ring 63, and because the holding piece 34 and the holding piece 35 are provided in plurality, even if a single holding piece 34 and holding piece 35 release other holding pieces 34 and holding pieces 35, they can continue to hold on the side wall of the catheter and push the catheter to move (the rotation shaft connection of the torsion springs can be provided between the holding piece 34 and the holding piece 35 and the sliding column 32 through the side wall).
An elastic clamping block 611 is arranged in the fixed point clamp 61, and the elastic clamping block 611 can be pushed to open by the holding piece 34 and the clamping piece 35 and release the limited interventional catheter.
The elastic clamping block 611 and the lateral sliding sleeve 521 are provided with an included angle ranging from 0 to 90 degrees, so that the interventional catheter in the fixed point clamp 61 can be pushed by the elastic clamping block 611 to be closely attached to the expansion sleeve 52.
The thickness of both ends of the expanding sleeve 631 is not greater than the thickness of the center of the expanding sleeve 631 in order to enable the holding piece 34 and the holding piece 35 to be pushed to expand.
The above embodiments are only exemplary embodiments of the present application and are not intended to limit the present application, the scope of which is defined by the claims. Various modifications and equivalent arrangements of this application will occur to those skilled in the art, and are intended to be within the spirit and scope of the application.
Claims (8)
1. A method of surface treatment of an interventional catheter, comprising the steps of:
s100, pretreatment: placing the intervention catheter into a sample chamber of a plasma generator, and carrying out wrapped plasma treatment on the side wall of the intervention catheter after introducing gas;
s200, modification treatment: immersing the pretreated interventional catheter in the grafting modification solution for a certain time, taking out the interventional catheter, and sequentially carrying out the surface cleaning and immersing treatment and the surface drying treatment of the interventional catheter;
s300, coating: coating a coupling agent and a coating solution on the surface of the interventional catheter obtained in the step S200 in sequence and curing;
s400, post-processing: immersing the interventional catheter obtained in the step S300 into strong ammonia water, taking out and drying;
the steps S100 and S200 are performed in a processing apparatus, which includes:
a vacuum chamber (1) capable of storing a plurality of solutions for soaking at the bottom;
the adjusting mechanism (2) is connected to the top of the vacuum chamber (1) in a penetrating way;
the rotating frame (3) is connected to the central position inside the vacuum chamber (1);
wherein the adjusting mechanism (2) comprises a lifting component (4), an expanding component (5) and a fixing component (6);
the lifting assembly (4) is connected to the top of the vacuum chamber (1) in a sealing way, one end of the lifting assembly (4) penetrates through the vacuum chamber (1) and extends to the outer side, the other end of the lifting assembly (4) is positioned in the vacuum chamber (1) and is connected with the expansion assembly (5), the side wall of the expansion assembly (5) is connected with the lifting assembly (4), and the fixing assembly (6) is connected to the side wall of the expansion assembly (5);
the fixing component (6) can fix the position of the interventional catheter and is provided with at least one annular treatment chamber on the side wall of the interventional catheter; the rotating frame (3) is used for clamping the intervention catheter and driving the intervention catheter to rotate around the center of the vacuum chamber (1) in the vacuum chamber (1) so as to enable the whole intervention catheter to pass through the annular treatment chamber; the lifting assembly (4) can insert a solution corresponding to the current interventional catheter position in a plurality of solutions with the interventional catheter;
the expansion assembly (5) is capable of changing the position of different solutions aligned by the interventional catheter;
the inner wall of the bottom of the vacuum chamber (1) is provided with a plurality of liquid storage channels (11), and the inner side wall of the vacuum chamber (1) is connected with a target sleeve (12);
the lifting assembly (4) comprises a sealing isolation sleeve (41) penetrating through the top of the vacuum chamber (1), the side wall of the sealing isolation sleeve (41) is in sealing connection with the vacuum chamber (1), an extension sleeve (42) is connected in the sealing isolation sleeve (41), one end, close to the vacuum chamber (1), of the extension sleeve (42) is connected with the expansion assembly (5), and the extension sleeve (42) can axially move in the sealing isolation sleeve (41);
the expansion assembly (5) comprises a limiting sleeve (51) connected with one end of the sealing isolation sleeve (41) positioned in the vacuum chamber (1), two ends of the limiting sleeve (51) are connected with an expansion sleeve (52), and the expansion sleeve (52) can axially move in the limiting sleeve (51) to change the position of an interventional catheter;
the fixed assembly (6) comprises a plurality of fixed point clamps (61) and at least one half-arc sleeve (62), wherein the fixed point clamps (61) are arranged along two side walls of the expansion sleeve (52), the fixed point clamps (61) are combined to form an annular structure, the fixed point clamps (61) are used for fixing the position for limiting the interventional catheter, the half-arc sleeve (62) is connected with the side walls of the limiting sleeve (51), and the half-arc sleeve (62) can be clung to the target sleeve (12) to form an unsealed wrapping ring (63) in a combined mode.
2. A surface treatment method of an interventional catheter according to claim 1, wherein,
rotating turret (3) are including setting up rotating disc (31) at the inside central point of vacuum chamber (1), the lateral wall rotation of rotating disc (31) is connected with slide column (32), the lateral wall cover of slide column (32) is equipped with pullback spring (33) of being connected with rotating disc (31), slide column (32) can take place to rotate the back with rotating disc (31) and is driven by pullback spring (33) and reset, one end that rotating disc (31) was kept away from to slide column (32) is connected with a plurality of holding piece (34), one side that slide column (32) was kept away from to holding piece (34) is equipped with a plurality of grip blocks (35) of being connected with slide column (32) rotation, holding piece (34) and grip block (35) one-to-one combination form the holder that is used for the centre gripping to intervene pipe.
3. A surface treatment method of an interventional catheter according to claim 2, wherein,
the expansion sleeve (52) comprises a sideways sliding sleeve (521) which is slidably connected in the limiting sleeve (51), one end of the sideways sliding sleeve (521) far away from the limiting sleeve (51) is connected with an end sliding sleeve (522), and the end sliding sleeve (522) can axially slide in the sideways sliding sleeve (521).
4. A surface treatment method of an interventional catheter according to claim 3, wherein,
the side wall of the limiting sleeve (51) is provided with a friction strip (511), the side wall of the friction strip (511) is provided with a pipe body rubbing strip (512), and the friction strip (511) and the pipe body rubbing strip (512) can be mutually adhered and clamp an intervention catheter between the friction strip and the pipe body rubbing strip;
a pulling column (513) connected with the pipe body rubbing strip (512) is arranged in the limiting sleeve (51), and the pulling column (513) can axially move in the sealing isolation sleeve (41) to reciprocally pull the pipe body rubbing strip (512) to rub the interventional catheter.
5. A surface treatment method of an interventional catheter according to claim 4, wherein,
a pair of expansion sleeves (631) are arranged at two ends of the wrapping ring (63), the expansion sleeves (631) are respectively connected with the half-arc sleeve (62) and the target sleeve (12) in one-to-one correspondence, and the expansion sleeves (631) can push the holding piece (34) and the clamping piece (35) to expand.
6. A surface treatment method of an interventional catheter according to claim 5, wherein,
an elastic clamping block (611) is arranged in the fixed point clamp (61), and the elastic clamping block (611) can be pushed by the fixing piece (34) and the clamping piece (35) to open and release the limited interventional catheter.
7. A surface treatment method of an interventional catheter according to claim 6, wherein,
an included angle is arranged between the elastic clamping block (611) and the lateral sliding sleeve (521), and the included angle ranges from 0 degrees to 90 degrees.
8. A surface treatment method of an interventional catheter according to claim 5, wherein,
the thickness of the two ends of the expanding sleeve (631) is not greater than the thickness of the center of the expanding sleeve (631).
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103326035A (en) * | 2013-06-17 | 2013-09-25 | 北京科技大学 | Automatic impregnating system for solid oxide fuel cell electrode |
| CN104558667A (en) * | 2014-07-15 | 2015-04-29 | 北京迪玛克医药科技有限公司 | Interventional catheter surface treatment method and interventional catheter |
| WO2018121352A1 (en) * | 2016-12-30 | 2018-07-05 | 先健科技(深圳)有限公司 | Drug-loading instrument and preparation method therefor |
| CN113599673A (en) * | 2021-08-21 | 2021-11-05 | 张莲 | Surface treatment device of anti-load medical cardiovascular intervention balloon catheter |
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| EP2995335B1 (en) * | 2014-09-11 | 2022-10-12 | Pine Medical Limited | Drug coated balloon catheter and method of manufacture thereof |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103326035A (en) * | 2013-06-17 | 2013-09-25 | 北京科技大学 | Automatic impregnating system for solid oxide fuel cell electrode |
| CN104558667A (en) * | 2014-07-15 | 2015-04-29 | 北京迪玛克医药科技有限公司 | Interventional catheter surface treatment method and interventional catheter |
| WO2018121352A1 (en) * | 2016-12-30 | 2018-07-05 | 先健科技(深圳)有限公司 | Drug-loading instrument and preparation method therefor |
| CN113599673A (en) * | 2021-08-21 | 2021-11-05 | 张莲 | Surface treatment device of anti-load medical cardiovascular intervention balloon catheter |
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