CN114432569A - Surface treatment method and equipment for interventional catheter - Google Patents
Surface treatment method and equipment for interventional catheter Download PDFInfo
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- CN114432569A CN114432569A CN202111671884.XA CN202111671884A CN114432569A CN 114432569 A CN114432569 A CN 114432569A CN 202111671884 A CN202111671884 A CN 202111671884A CN 114432569 A CN114432569 A CN 114432569A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M25/0045—Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
- A61M2025/0046—Coatings for improving slidability
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E30/00—Energy generation of nuclear origin
- Y02E30/10—Nuclear fusion reactors
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Abstract
The invention discloses a surface treatment method of an interventional catheter, which comprises the following steps: s100, preprocessing: the method comprises the following steps of placing an interventional conduit into a sample chamber of a plasma generator, and carrying out wrapping type plasma treatment on the side wall of the interventional conduit after introducing gas, wherein the interventional conduit can be subjected to wrapping type regional treatment during surface treatment through a fixing component so as to avoid uneven surface treatment caused by the fact that the interventional conduit is shielded by a clamping device; then the rotating frame can clamp the interventional catheter and drive the interventional catheter to rotate around the center of the vacuum chamber in the vacuum chamber so that the whole interventional catheter passes through the annular processing chamber; then the lifting component is inserted into the solution corresponding to the current position of the interventional catheter in the multiple solutions with the interventional catheter; the stent assembly is then caused to alter the position of the different solutions aligned with the interventional catheter.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a surface treatment method and equipment of an interventional catheter.
Background
The high lubricity is one of the very important performances of the intravascular interventional catheter, and when the catheter enters and exits a blood vessel and moves in the blood vessel, the high lubricity can inhibit the adhesion of macromolecules in blood such as plasma protein, platelets and the like on the surface of a material, reduce the damage to the blood vessel wall and blood cells, relieve the disturbance to the laminar flow of the blood and avoid the occurrence of coagulation reaction.
In the prior art, there are a plurality of operation modes for surface treatment of an interventional catheter, wherein an important step is surface treatment of the catheter, the interventional catheter is placed in a sample chamber of a plasma generator during treatment, and plasma treatment is performed after gas is introduced, for example, in the invention patent with the application number of 202110964059.2, the invention discloses a surface treatment device for an anti-unloading medical cardiovascular interventional balloon catheter, which performs pretreatment on the surface of the catheter, a motor drives a turntable to rotate, an elliptical groove controls the movement of a pull rod to stretch a rope B, two connecting rods drive two clamping rings to deflect while moving in a movable hole until the cardiovascular balloon catheter is stably clamped, then the motor is turned off, a foot pedal drives a cross rod to move downwards, the rope A drives an L-shaped clamping rod to move in the moving process of the cross rod, until L type kelly and L type groove block, square piece just shifted out from the square groove this moment, then people can rotate the processing dish limit and carry out surface treatment to cardiovascular sacculus pipe, has greatly improved efficiency, that is to say can be to the firm centre gripping of cardiovascular sacculus pipe in, can rotate the limit and carry out surface treatment work, has greatly improved work efficiency.
However, this operation has limitations when the surface treatment is not uniform, for example, when the interventional catheter is subjected to surface treatment, the interventional catheter is directly driven by the turntable to rotate around the turntable, but the surface of the catheter itself is limited by the clamping device, so that the surface of the catheter is easily shaded, and the treatment on the surface of the catheter is not uniform.
Therefore, the surface treatment equipment for the interventional catheter in the prior art cannot solve the problem that the catheter is easily shielded by the clamping device to cause uneven surface treatment when the surface treatment is carried out on the catheter.
Disclosure of Invention
The invention aims to provide a surface treatment method and equipment for an interventional catheter, which aim to solve the technical problem that the catheter is easily shielded by a clamping device to cause uneven surface treatment when the surface treatment is carried out on the catheter in the prior art.
In order to solve the technical problems, the invention specifically provides the following technical scheme,
a surface treatment method of an interventional catheter, comprising the steps of:
s100, preprocessing: placing the interventional conduit into a sample chamber of a plasma generator, and carrying out wrapped plasma treatment on the side wall of the interventional conduit after introducing gas;
s200, modification treatment: soaking the pretreated interventional catheter in the grafting modification solution for a certain time, taking out the interventional catheter, and sequentially performing interventional catheter surface cleaning and soaking treatment and interventional catheter surface drying treatment;
s300, coating a coating: coating the coupling agent and the coating solution on the surface of the interventional catheter obtained in the step S200 in sequence and curing;
s400, post-processing: and (5) immersing the interventional catheter obtained in the step (S300) into concentrated ammonia water, taking out and drying.
In order to solve the above technical problem, the present invention further provides a processing apparatus for a surface processing method of an interventional catheter, wherein the steps S100 and S200 are performed in the processing apparatus:
the processing equipment comprises
A vacuum chamber capable of storing a plurality of solutions for soaking at the bottom;
the adjusting mechanism is connected to the top of the vacuum chamber in a penetrating way;
the rotating frame is connected to the center position in the vacuum chamber;
the adjusting mechanism comprises a lifting assembly, an expansion assembly and a fixing assembly;
the lifting assembly is connected to the top of the vacuum chamber in a sealing mode, one end of the lifting assembly penetrates through the vacuum chamber and extends to the outside, the other end of the lifting assembly is located in the vacuum chamber and is connected with the expansion assembly, the side wall of the expansion assembly is connected with the lifting assembly, and the fixing assembly is connected to the side wall of the expansion assembly;
the fixing component can fix the position of the interventional catheter and is provided with at least one annular processing chamber on the side wall of the interventional catheter; the rotating frame is used for clamping the interventional catheter and driving the interventional catheter to rotate around the center of the vacuum chamber in the vacuum chamber so that the whole interventional catheter passes through the annular processing chamber; the lifting assembly can insert the interventional catheter into a solution corresponding to the current interventional catheter position in a plurality of solutions; the stent assembly is capable of changing the position of different solutions aligned by the interventional catheter.
As a preferred scheme of the invention, the inner wall of the bottom of the vacuum chamber is provided with a plurality of liquid storage channels, and the inner side wall of the vacuum chamber is connected with a target sleeve;
the lifting assembly comprises a sealing isolation sleeve penetrating through the top of the vacuum chamber, the side wall of the sealing isolation sleeve is connected with the vacuum chamber in a sealing manner, an extension sleeve is connected in the sealing isolation sleeve, one end, close to the vacuum chamber, of the extension sleeve is connected with the expansion assembly, and the extension sleeve can axially move in the sealing isolation sleeve;
the expansion assembly comprises a limiting sleeve connected with one end of the sealing isolation sleeve, which is positioned at the vacuum chamber, two ends of the limiting sleeve are respectively connected with an expansion sleeve, and the expansion sleeves can axially move in the limiting sleeve to change the position of the interventional catheter;
the fixed subassembly includes a plurality of fixed point presss from both sides and at least one half arc cover, and is a plurality of fixed point presss from both sides along two expansion cover lateral wall sets up, and is a plurality of fixed point presss from both sides the combination forms annular structure, fixed point presss from both sides the position that is used for fixed restriction to intervene the pipe, half arc cover is connected the lateral wall of restriction cover, half arc cover can hug closely the target cover with the combination formation enclosed parcel ring.
As a preferable scheme of the invention, the rotating frame comprises a rotating disc arranged at the central position in the vacuum chamber, the side wall of the rotating disc is rotatably connected with a sliding column, the side wall of the sliding column is sleeved with a pull-back spring connected with the rotating disc, the sliding column can be driven by the pull-back spring to reset after rotating with the rotating disc, one end of the sliding column, which is far away from the rotating disc, is connected with a plurality of holding pieces, one side of the holding pieces, which is far away from the sliding column, is provided with a plurality of clamping pieces rotatably connected with the sliding column, and the holding pieces and the clamping pieces are combined in a one-to-one correspondence manner to form a clamp holder for clamping an interventional catheter.
As a preferable scheme of the present invention, the expansion sleeve includes a side body sliding sleeve slidably connected in the limiting sleeve, one end of the side body sliding sleeve, which is far away from the limiting sleeve, is connected with an end sliding sleeve, and the end sliding sleeve can axially slide in the side body sliding sleeve.
As a preferred scheme of the invention, a friction strip is mounted on the side wall of the limiting sleeve, a pipe body kneading strip is arranged on the side wall of the friction strip, and the friction strip and the pipe body kneading strip can be mutually attached and clamp the intervention conduit between the friction strip and the pipe body kneading strip;
and a pulling column connected with the tube body rubbing strip is arranged in the limiting sleeve, and the pulling column can axially move in the sealing isolation sleeve to pull the tube body rubbing strip back and forth to rub the interventional catheter.
As a preferable scheme of the invention, a pair of opening sleeves are respectively arranged at two ends of the wrapping ring, the pair of opening sleeves are respectively connected with the semi-arc sleeve and the target sleeve in a one-to-one correspondence manner, and the pair of opening sleeves can push the holding sheet and the clamping sheet to open.
In a preferred embodiment of the present invention, an elastic clamping block is disposed in the fixing point clamp, and the elastic clamping block can be pushed by the holding piece and the clamping piece to expand and release the limited interventional catheter.
As a preferable scheme of the invention, an included angle is arranged between the elastic clamping block and the side sliding sleeve, and the included angle ranges from 0 degree to 90 degrees.
In a preferable mode of the invention, the thickness of the two ends of the expanding sleeve is not more than the thickness of the central position of the expanding sleeve.
Compared with the prior art, the invention has the following advantages,
according to the invention, the intervention catheter can be subjected to wrapped regional treatment during surface treatment through the fixing component so as to avoid uneven surface treatment caused by the fact that the intervention catheter is shielded by the clamping device; then the rotating frame can clamp the interventional catheter and drive the interventional catheter to rotate around the center of the vacuum chamber in the vacuum chamber so that the whole interventional catheter passes through the annular processing chamber; then the lifting component is inserted into the solution corresponding to the current position of the interventional catheter in the multiple solutions with the interventional catheter; the stent assembly is then caused to alter the position of the different solutions aligned with the interventional catheter.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below. It should be apparent that the drawings in the following description are merely exemplary, and that other embodiments can be derived from the drawings provided by those of ordinary skill in the art without inventive effort.
FIG. 1 is a schematic diagram of the overall structure of an embodiment of the present invention;
FIG. 2 is a schematic view of a vacuum chamber according to an embodiment of the present invention;
FIG. 3 is a schematic structural view of the sliding sleeve when the sliding sleeve is not opened;
FIG. 4 is a schematic structural view of the embodiment of the present invention when the sliding sleeve is opened;
FIG. 5 is a schematic view of a structure of a tubular body kneading bar according to an embodiment of the present invention;
FIG. 6 is a top view of a sliding column in accordance with an embodiment of the present invention;
fig. 7 is a flowchart of surface treatment of an interventional catheter in accordance with an embodiment of the present invention.
Reference numerals in the figures denote the following respectively,
1-vacuum chamber; 2-an adjustment mechanism; 3-a rotating frame; 4-a lifting assembly; 5-an expansion component; 6-a fixing component;
11-a liquid storage channel; 12-a target sleeve; 31-a rotating disc; 32-a sliding column; 33-a pull back spring; 34-a holding sheet; 35-a clamping piece; 41-sealing the isolation sleeve; 42-an extension sleeve;
51-a restraining sleeve; 52-an expansion sleeve;
61-fixation point clamp; 62-half arc sleeve; 63-wrapping a ring;
511-rubbing strip; 512-rubbing the tube body with rubbing strips; 513-pulling the column; 521-side sliding sleeve; 522-end sliding sleeve; 611-elastic clamping blocks; 631-flaring sleeve.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in fig. 7, the present invention provides a surface treatment method of an interventional catheter, comprising the steps of:
s100, preprocessing: placing the interventional catheter into a sample chamber of a plasma generator, introducing gas, and performing wrapping type plasma treatment on the side wall of the interventional catheter, wherein the discharge power is 10W to 310W, and the treatment time is 1min to 5 min;
s200, modification treatment: soaking the pretreated interventional catheter in a grafting modification solution for a certain time, taking out, and sequentially performing interventional catheter surface cleaning and soaking treatment and interventional catheter surface drying treatment, wherein the grafting modification solution is a solution composed of glycidyl methacrylate and a first organic solvent, the mass percentage concentration of the glycidyl methacrylate in the solution is 5-95%, the temperature of the grafting modification treatment is 30-90 ℃, the soaking time of the interventional catheter is 2-24 h, the drying temperature of the drying treatment is 65-75 ℃, and the drying time is 10-14 h;
s300, coating a coating: applying a coupling agent and a coating solution to the surface of the interventional catheter obtained in step S200 in sequence and curing, wherein the coupling agent is applied first (for example, epoxy-containing siloxane is applied) to increase the adhesion of the coating solution;
s400, post-processing: and (5) immersing the interventional catheter obtained in the step (S300) into concentrated ammonia water, taking out and drying.
In this embodiment, compared with the prior art, the method can perform the wrapped plasma treatment on the side wall of the interventional catheter during the pretreatment process (i.e. in the case of the normal treatment, the treatment is performed outside the catheter by surrounding the interventional catheter regionally for the interventional catheter resynchronization during the normal treatment).
The specific treatment of the surface treatment method of the interventional catheter is as follows: the surface treatment efficiency is increased mainly by the action of the wrapping plasma treatment, the adhesion force increasing treatment is performed on the surface of the catheter through the surface treatment by the coupling agent, and other stages are the same as the prior art.
Example 2:
as shown in fig. 1, a processing apparatus for a surface processing method, steps S100 and S200 each perform in the processing apparatus:
the processing equipment comprises
A vacuum chamber 1 capable of storing a plurality of solutions for soaking at the bottom;
the adjusting mechanism 2 is connected to the top of the vacuum chamber 1 in a penetrating way;
a rotating frame 3 connected to the center position inside the vacuum chamber 1;
wherein, the adjusting mechanism 2 comprises a lifting component 4, an expansion component 5 and a fixing component 6;
the lifting assembly 4 is connected to the top of the vacuum chamber 1 in a sealing manner, one end of the lifting assembly 4 penetrates through the vacuum chamber 1 and extends to the outside, the other end of the lifting assembly 4 is positioned in the vacuum chamber 1 and is connected with the expansion assembly 5, the side wall of the expansion assembly 5 is connected with the lifting assembly 4, and the fixing assembly 6 is connected to the side wall of the expansion assembly 5;
the fixing assembly 6 is capable of fixing the position of the interventional catheter and providing at least one annular processing chamber in the side wall of the interventional catheter; the rotating frame 3 is used for clamping the interventional catheter and driving the interventional catheter to rotate around the center of the vacuum chamber 1 in the vacuum chamber 1 so that the whole interventional catheter passes through the annular processing chamber; the lifting component 4 can insert the interventional catheter into a solution corresponding to the current interventional catheter position in a plurality of solutions; the stent assembly 5 is capable of changing the position of different solutions to be registered with the interventional catheter.
The treatment equipment can carry out wrapped regional treatment on the interventional catheter during surface treatment through the fixing component 6 so as to avoid uneven surface treatment caused by the fact that the interventional catheter is shielded by the clamping device, and during specific implementation, the fixing component 6 can fix the position of the interventional catheter and at least one annular treatment chamber is arranged on the side wall of the interventional catheter; then the rotating frame 3 can clamp the interventional catheter and drive the interventional catheter to rotate around the center of the vacuum chamber 1 in the vacuum chamber 1 so that the whole interventional catheter passes through the annular processing chamber; then the lifting component 4 is inserted into the solution corresponding to the current position of the interventional catheter in the multiple solutions with the interventional catheter; the stent assembly 5 is then caused to alter the position of the different solutions aligned with the interventional catheter.
As shown in fig. 1 and 2, the inner wall of the bottom of the vacuum chamber 1 is provided with a plurality of liquid storage channels 11, and the inner side wall of the vacuum chamber 1 is connected with a target sleeve 12;
the lifting assembly 4 comprises a sealing isolation sleeve 41 which penetrates through the top of the vacuum chamber 1, the side wall of the sealing isolation sleeve 41 is connected with the vacuum chamber 1 in a sealing manner, an extension sleeve 42 is connected in the sealing isolation sleeve 41, one end of the extension sleeve 42, which is close to the vacuum chamber 1, is connected with the expansion assembly 5, and the extension sleeve 42 can axially move in the sealing isolation sleeve 41;
the expansion assembly 5 comprises a limiting sleeve 51 connected with the sealing isolation sleeve 41 at one end of the vacuum chamber 1, an expansion sleeve 52 is connected with both ends of the limiting sleeve 51, and the expansion sleeve 52 can axially move in the limiting sleeve 51 to change the position of the interventional catheter;
the fixing assembly 6 comprises a plurality of fixing point clamps 61 and at least one half arc sleeve 62, the fixing point clamps 61 are arranged along the side walls of the two expansion sleeves 52, the fixing point clamps 61 are combined to form a ring-shaped structure, the fixing point clamps 61 are used for fixing and limiting the position of the interventional catheter, the half arc sleeve 62 is connected to the side wall of the limiting sleeve 51, and the half arc sleeve 62 can be tightly attached to the target sleeve 12 to be combined to form an unclosed wrapping ring 63.
In order to realize the action of wrapping type regional treatment during surface treatment of the interventional catheter, during specific work, the interventional catheter is directly clamped between the fixing point clamps 61, and meanwhile, the interventional catheter is located in the wrapping ring 63 (the interventional catheter is not connected at the first position), once the interventional catheter is driven by the rotating frame 3 to rotate around the rotating frame 3, the interventional catheter can slide along the axis of the wrapping ring 63 at the moment, and the wrapping ring 63 is wrapped in the process (the target sleeve 12 can be evaporated by means of the principle of electric arc evaporation coating during surface pretreatment in the prior art), the wrapping ring 63 can wrap and cover more surface areas of the interventional catheter, so that the pretreatment effect of the interventional catheter is better.
After the pretreatment is finished, the interventional catheter needs to be modified, namely, soaked by different solutions, but the modification treatment can also be carried out in the vacuum chamber 1 (namely, the pretreated vacuum chamber 1 is vacuumized to ensure that the drying effect is better, namely, vacuum drying), after the working environment treatment, the extension sleeve 42 can axially move in the sealing isolation sleeve 41 to ensure that the interventional catheter is soaked in the first solution, then the interventional catheter is lifted, and the expansion sleeve 52 axially moves in the limiting sleeve 51 to change the position of the interventional catheter, so that the interventional catheter is changed from being aligned with the storage liquid channel 11 in which the first solution is stored to being aligned with the storage liquid channel 11 in which the second solution is stored, and then the interventional catheter is put down to the second solution.
As shown in fig. 1 and 6, the rotating frame 3 includes a rotating disc 31 disposed at the central position inside the vacuum chamber 1, a sliding column 32 is rotatably connected to a side wall of the rotating disc 31, a pull-back spring 33 connected to the rotating disc 31 is sleeved on a side wall of the sliding column 32, the sliding column 32 can be driven by the pull-back spring 33 to reset after rotating with the rotating disc 31, one end of the sliding column 32, which is far away from the rotating disc 31, is connected with a plurality of fixing pieces 34, one side of the fixing pieces 34, which is far away from the sliding column 32, is provided with a plurality of clamping pieces 35 rotatably connected to the sliding column 32, and the fixing pieces 34 and the clamping pieces 35 are combined in a one-to-one correspondence to form a clamp for clamping an interventional catheter.
The pull-back spring 33 is specifically configured as shown in fig. 1, and has a larger end and a smaller end, so as not to affect the elastic return capability and the deflection capability.
When concrete during operation again, drive rolling disc 31 through external drive and rotate, later pivoted rolling disc 31 can drive the holder through slip post 32 and rotate together, because of solid piece 34 and holding piece 35 all set up a plurality ofly, so the holder is applyed the clamping-force of interveneeing on the pipe again and is had many places, even there is one and relaxs other play and also can continue the centre gripping, and the setting of a plurality of holders still can play the purpose that the pipe end was intervened in the firm, make and intervene the pipe end and can not appear crooked perk phenomenon at the in-process of moving about again.
The expansion sleeve 52 comprises a side body sliding sleeve 521 which is slidably connected in the limiting sleeve 51, one end of the side body sliding sleeve 521, which is far away from the limiting sleeve 51, is connected with an end sliding sleeve 522, and the end sliding sleeve 522 can axially slide in the side body sliding sleeve 521.
When the expanding sleeve 52 is expanded again, the side sliding sleeve 521 can slide out of the limiting sleeve 51 by injecting gas into the limiting sleeve 51, and the end sliding sleeve 522 can slide out of the side sliding sleeve 521, that is, the end sliding sleeve moves from the state shown in fig. 3 to the state shown in fig. 4.
As shown in fig. 1 and 5, a friction strip 511 is mounted on the side wall of the limiting sleeve 51, a tube kneading strip 512 is arranged on the side wall of the friction strip 511, and the friction strip 511 and the tube kneading strip 512 can be mutually attached and clamp the interventional catheter therebetween;
a pulling column 513 connected to the tube rubbing strip 512 is provided in the restraining sleeve 51, and the pulling column 513 is axially movable within the sealing and isolating sleeve 41 to pull the tube rubbing strip 512 back and forth to frictionally intervene in the catheter.
As shown in FIG. 5, the side wall of the restricting sleeve 51 is provided with a sliding slot at a position corresponding to the tube kneading bar 512, and an insulating film may be mounted on the pulling column 513 to prevent gas from entering the vacuum chamber 1 through the sliding slot.
When the re-catheter slides, the catheter is easily blocked, so that the re-catheter is driven to slide, the small motor is driven by the driver to drive the pulling column 513 to axially move in the sealing isolation sleeve 41 to pull the tube rubbing strip 512 back and forth to rub the interventional catheter, and then the rubbed interventional catheter rotates to enable the whole interventional catheter surface to be fully pretreated.
The two ends of the wrapping ring 63 are provided with a pair of opening sleeves 631, the pair of opening sleeves 631 are respectively connected with the half arc sleeve 62 and the target sleeve 12 in a one-to-one correspondence manner, and the pair of opening sleeves 631 can push the holding pieces 34 and the clamping pieces 35 to open.
The operation is to prevent the conduit from being shielded when the conduit enters the wrapping ring 63 through the fixing piece 34 and the clamping piece 35, and even if the single fixing piece 34 and the clamping piece 35 loosen other fixing pieces 34 and clamping pieces 35, the conduit can be continuously clamped and pushed to move (the fixing piece 34 and the clamping piece 35 can be connected with the sliding column 32 through the rotating shaft provided with the torsion springs on the side walls).
The fixing point clamp 61 is provided with a flexible clamping block 611, and the flexible clamping block 611 can be pushed by the holding piece 34 and the clamping piece 35 to expand and release the limited interventional catheter.
An included angle is arranged between the elastic clamping block 611 and the side sliding sleeve 521, the included angle ranges from 0 to 90 degrees, and the included angle is arranged so that the interventional catheter in the fixing point clamp 61 can be pushed by the elastic clamping block 611 to cling to the expansion sleeve 52.
The thickness of the two ends of the expanding sleeve 631 is not larger than the thickness of the central position of the expanding sleeve 631, so that the holding piece 34 and the clamping piece 35 can be pushed to expand.
The above embodiments are only exemplary embodiments of the present application, and are not intended to limit the present application, and the protection scope of the present application is defined by the claims. Various modifications and equivalents may be made by those skilled in the art within the spirit and scope of the present application and such modifications and equivalents should also be considered to be within the scope of the present application.
Claims (10)
1. A method for surface treatment of an interventional catheter, comprising the steps of:
s100, preprocessing: placing the interventional conduit into a sample chamber of a plasma generator, and carrying out wrapped plasma treatment on the side wall of the interventional conduit after introducing gas;
s200, modification treatment: soaking the pretreated interventional catheter in the grafting modification solution for a certain time, taking out the interventional catheter, and sequentially performing interventional catheter surface cleaning and soaking treatment and interventional catheter surface drying treatment;
s300, coating a coating: coating the coupling agent and the coating solution on the surface of the interventional catheter obtained in the step S200 in sequence and curing;
s400, post-processing: and (5) immersing the interventional catheter obtained in the step (S300) into concentrated ammonia water, taking out and drying.
2. A treatment device for use in a method for surface treatment of an interventional catheter as defined in claim 1, wherein both steps S100 and S200 are performed in the treatment device:
the processing equipment comprises
A vacuum chamber (1) capable of storing a plurality of solutions for soaking at the bottom;
the adjusting mechanism (2) is connected to the top of the vacuum chamber (1) in a penetrating way;
the rotating frame (3) is connected to the central position in the vacuum chamber (1);
wherein the adjusting mechanism (2) comprises a lifting component (4), an expansion component (5) and a fixing component (6);
the lifting assembly (4) is connected to the top of the vacuum chamber (1) in a sealing mode, one end of the lifting assembly (4) penetrates through the vacuum chamber (1) and extends to the outside, the other end of the lifting assembly (4) is located in the vacuum chamber (1) and is connected with the expansion assembly (5), the side wall of the expansion assembly (5) is connected with the lifting assembly (4), and the fixing assembly (6) is connected to the side wall of the expansion assembly (5);
the fixing component (6) can fix the position of the interventional catheter and is provided with at least one annular processing chamber on the side wall of the interventional catheter; the rotating frame (3) is used for clamping the interventional catheter and driving the interventional catheter to rotate around the center of the vacuum chamber (1) in the vacuum chamber (1) so that the whole interventional catheter passes through the annular processing chamber; the lifting assembly (4) can be used for inserting the interventional catheter into a solution corresponding to the current interventional catheter position in various solutions; the stent assembly (5) is capable of changing the position of different solutions aligned with the interventional catheter.
3. The processing apparatus for the surface processing method of the interventional catheter as defined in claim 2, characterized in that the bottom inner wall of the vacuum chamber (1) is provided with a plurality of liquid storage channels (11), and the inner wall of the vacuum chamber (1) is connected with a target sleeve (12);
the lifting assembly (4) comprises a sealing isolation sleeve (41) penetrating through the top of the vacuum chamber (1), the side wall of the sealing isolation sleeve (41) is connected with the vacuum chamber (1) in a sealing manner, an extension sleeve (42) is connected in the sealing isolation sleeve (41), one end, close to the vacuum chamber (1), of the extension sleeve (42) is connected with the expansion assembly (5), and the extension sleeve (42) can move axially in the sealing isolation sleeve (41);
the expansion assembly (5) comprises a limiting sleeve (51) connected with the sealing isolation sleeve (41) at one end of the vacuum chamber (1), an expansion sleeve (52) is connected to each end of the limiting sleeve (51), and the expansion sleeve (52) can axially move in the limiting sleeve (51) to change the position of an interventional catheter;
the fixing assembly (6) comprises a plurality of fixing point clamps (61) and at least one half arc sleeve (62), the fixing point clamps (61) are arranged along two side walls of the expansion sleeve (52), the fixing point clamps (61) are combined to form an annular structure, the fixing point clamps (61) are used for fixing and limiting the position of an interventional catheter, the half arc sleeve (62) is connected to the side wall of the limiting sleeve (51), and the half arc sleeve (62) can be tightly attached to the target sleeve (12) to form an unclosed wrapping ring (63) in a combined mode.
4. A treatment device for a method of surface treatment of an interventional catheter as defined in claim 3, it is characterized in that the rotating frame (3) comprises a rotating disc (31) arranged at the central position in the vacuum chamber (1), the side wall of the rotating disc (31) is rotatably connected with a sliding column (32), the side wall of the sliding column (32) is sleeved with a pull-back spring (33) connected with the rotating disc (31), the sliding column (32) can be driven by a pull-back spring (33) to reset after rotating with the rotating disc (31), one end of the sliding column (32) far away from the rotating disc (31) is connected with a plurality of fixing pieces (34), a plurality of clamping sheets (35) which are rotatably connected with the sliding column (32) are arranged on one side of the fixing sheet (34) far away from the sliding column (32), the holding sheets (34) and the clamping sheets (35) are correspondingly combined one by one to form a clamp holder for clamping the interventional catheter.
5. Treatment equipment for a method for the superficial treatment of an interventional catheter according to claim 4, characterized in that the dilatation sleeve (52) comprises a lateral sliding sleeve (521) slidably connected inside the limiting sleeve (51), wherein an end sliding sleeve (522) is connected to one end of the lateral sliding sleeve (521) far away from the limiting sleeve (51), and the end sliding sleeve (522) can slide axially inside the lateral sliding sleeve (521).
6. Treatment apparatus for a method of surface treatment of interventional catheters according to claim 5, characterised in that the side wall of the restraining sleeve (51) is fitted with a friction strip (511), the side wall of the friction strip (511) is provided with a tube rub strip (512), the friction strip (511) and the tube rub strip (512) being able to engage each other and clamp an interventional catheter between them;
a pulling column (513) connected with the tube body rubbing strip (512) is arranged in the limiting sleeve (51), and the pulling column (513) can axially move in the sealing isolation sleeve (41) to pull the tube body rubbing strip (512) back and forth to rub the interventional catheter.
7. The treatment apparatus for the surface treatment method of the interventional catheter as defined in claim 6, wherein the wrapping ring (63) is provided at both ends thereof with a pair of expanding sleeves (631), the pair of expanding sleeves (631) are respectively connected to the half-arc sleeve (62) and the target sleeve (12) in a one-to-one correspondence, and the pair of expanding sleeves (631) can push the holding pieces (34) and the holding pieces (35) to expand.
8. Treatment device for a method of surface treatment of interventional catheters according to claim 7, characterised in that inside the fixation point clamp (61) a resilient clamping block (611) is arranged, which resilient clamping block (611) can be pushed by the holding piece (34) and the clamping piece (35) to expand and release the restricted interventional catheter.
9. Treatment equipment for a surface treatment method of an interventional catheter as defined in claim 8, wherein an angle is provided between the resilient clamp block (611) and the lateral sliding sleeve (521), the angle being in the range of 0-90 degrees.
10. Treatment device for a method of surface treatment of interventional catheters according to claim 7, characterised in that the thickness of the two ends of the flaring sleeve (631) is not greater than the thickness of the flaring sleeve (631) at the centre position.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111671884.XA CN114432569B (en) | 2021-12-31 | 2021-12-31 | Surface treatment method and equipment for interventional catheter |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111671884.XA CN114432569B (en) | 2021-12-31 | 2021-12-31 | Surface treatment method and equipment for interventional catheter |
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| CN114432569A true CN114432569A (en) | 2022-05-06 |
| CN114432569B CN114432569B (en) | 2023-08-29 |
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Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103326035A (en) * | 2013-06-17 | 2013-09-25 | 北京科技大学 | Automatic impregnating system for solid oxide fuel cell electrode |
| CN104558667A (en) * | 2014-07-15 | 2015-04-29 | 北京迪玛克医药科技有限公司 | Interventional catheter surface treatment method and interventional catheter |
| US20160074633A1 (en) * | 2014-09-11 | 2016-03-17 | Pine Medical Limited | Drug Coated Balloon Catheter and Method of Manufacture Thereof |
| WO2018121352A1 (en) * | 2016-12-30 | 2018-07-05 | 先健科技(深圳)有限公司 | Drug-loading instrument and preparation method therefor |
| CN113599673A (en) * | 2021-08-21 | 2021-11-05 | 张莲 | Surface treatment device of anti-load medical cardiovascular intervention balloon catheter |
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2021
- 2021-12-31 CN CN202111671884.XA patent/CN114432569B/en active Active
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103326035A (en) * | 2013-06-17 | 2013-09-25 | 北京科技大学 | Automatic impregnating system for solid oxide fuel cell electrode |
| CN104558667A (en) * | 2014-07-15 | 2015-04-29 | 北京迪玛克医药科技有限公司 | Interventional catheter surface treatment method and interventional catheter |
| US20160074633A1 (en) * | 2014-09-11 | 2016-03-17 | Pine Medical Limited | Drug Coated Balloon Catheter and Method of Manufacture Thereof |
| WO2018121352A1 (en) * | 2016-12-30 | 2018-07-05 | 先健科技(深圳)有限公司 | Drug-loading instrument and preparation method therefor |
| CN113599673A (en) * | 2021-08-21 | 2021-11-05 | 张莲 | Surface treatment device of anti-load medical cardiovascular intervention balloon catheter |
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| CN114432569B (en) | 2023-08-29 |
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