CN114414488A - Nondestructive blood bag plasma chyle index measuring method - Google Patents

Nondestructive blood bag plasma chyle index measuring method Download PDF

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CN114414488A
CN114414488A CN202210079537.6A CN202210079537A CN114414488A CN 114414488 A CN114414488 A CN 114414488A CN 202210079537 A CN202210079537 A CN 202210079537A CN 114414488 A CN114414488 A CN 114414488A
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plasma
index
chyle
blood bag
light intensity
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CN114414488B (en
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刘�英
刘运保
张志亮
黄勇华
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Qingyuan Central Blood Station Qingyuan Institute Of Blood Transfusion
Qingyuan Polytechnic
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Qingyuan Central Blood Station Qingyuan Institute Of Blood Transfusion
Qingyuan Polytechnic
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity

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Abstract

The invention provides a nondestructive measuring method for plasma chyle index of blood bag, comprising the following steps: acquiring a first light intensity value I1 of the light source after the light source passes through the blood bag with the first thickness value h 1; obtaining a second light intensity value I2 after the light source passes through the blood bag with the second thickness value h 2; calculating the chyle index of the plasma according to the first light intensity value I1 and the second light intensity value I2; wherein the second thickness value h2 is smaller than the second thickness value h 1. The invention does not need to extract plasma from the blood bag for chyle index measurement, and solves the problems that the existing blood bag plasma chyle index measurement method needs to extract partial plasma from the blood bag for measurement, and the plasma loss and the risk of secondary pollution exist.

Description

Nondestructive blood bag plasma chyle index measuring method
Technical Field
The invention relates to the technical field of material analysis, in particular to a nondestructive testing method for plasma chyle index of blood bag.
Background
Plasma chyle index is an important parameter in determining whether plasma can be clinically used, and plasma with excessive chyle is not suitable for clinical use. For the measurement of chyle index of blood bag plasma, the existing methods all need to extract part of plasma from the blood bag, then inject the extracted plasma into some transparent containers with fixed shapes, and finally measure the chyle index by methods such as an exponential method, a turbidimetric method, an enzyme-linked immunosorbent nephelometric method, a full-automatic enzyme immunoassay method, a biochemical analyzer method, plasma chyle detection based on CCD and the like.
However, the existing methods for measuring the plasma chyle index of the blood bag require that part of the plasma is extracted from the blood bag for measurement, and the plasma loss and the risk of secondary pollution exist.
Disclosure of Invention
Based on the above, in order to solve the problems that the existing blood bag plasma chyle index measuring method needs to extract partial plasma from the blood bag for measurement, and the risk of plasma loss and secondary pollution exists, the invention provides a nondestructive blood bag plasma chyle index measuring method, which has the following specific technical scheme:
a nondestructive measurement method for plasma chyle index of blood bag comprises the following steps:
s1, obtaining a first light intensity value I1 of the blood bag after the light source passes through the first thickness value h 1.
S2, obtaining a second light intensity value I2 of the blood bag after the light source passes through the second thickness value h 2.
S3, calculating the chyle index of the plasma according to the first light intensity value I1 and the second light intensity value I2.
The method for measuring the plasma chyle index of the lossless blood bag does not need to extract plasma from the blood bag for measuring the chyle index, and solves the problems that the existing method for measuring the plasma chyle index of the blood bag needs to extract partial plasma from the blood bag for measuring, and the plasma loss and the risk of secondary pollution exist.
Wherein the second thickness value h2 is smaller than the second thickness value h 1.
Further, the chyle index x ═ of the plasma (2A)bx/Ab1) -1, wherein,
Figure BDA0003485538470000021
Figure BDA0003485538470000022
i3 is the third light intensity value after the light source transmits the plasma with chyle index of 1 at the first thickness value h1, and I4 is the fourth light intensity value after the light source transmits the plasma with chyle index of 1 at the second thickness value h 2.
Wherein, the plasma with chyle index of 1 refers to the ratio of 1: 1 proportion is diluted by colorless transparent normal saline, and the blood fat concentration is changed to the original
Figure BDA0003485538470000023
Plasma with a back transmittance identical to that of normal plasma.
Further, the chyle index x ═ log of the plasma2((3A2#bx/A2#b1) -1), wherein,
Figure BDA0003485538470000024
i3 is the third light intensity value after the light source transmits the plasma with chyle index of 1 at the first thickness value h1, and I4 is the fourth light intensity value after the light source transmits the plasma with chyle index of 1 at the second thickness value h 2.
Wherein the plasma with chyle index of 1 refers to a plasma with chyle index of 1: 2 proportion is diluted by colorless transparent normal saline, and the blood fat concentration is changed to the original
Figure BDA0003485538470000025
Plasma with a back transmittance identical to that of normal plasma.
Further, a light intensity signal is generated by the light sensor, and the light intensity signal of the light source after passing through the blood bag with the first thickness value h1 is converted into a first light intensity value by the control module, and the light intensity signal of the light source after passing through the blood bag with the second thickness value h2 is converted into a second light intensity value.
Further, the blood bag is located between the light source and the light sensor.
Further, an optical filter is arranged between the blood bag and the optical sensor.
Further, the light source is a monochromatic light source.
A computer-readable storage medium, in which a computer program is stored which, when being executed by a processor, carries out the method of non-destructive blood bag plasma chylomicron index measurement.
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The invention will be further understood from the following description in conjunction with the accompanying drawings. The components in the figures are not necessarily to scale, emphasis instead being placed upon illustrating the principles of the embodiments. Like reference numerals designate corresponding parts throughout the different views.
Fig. 1 is a schematic overall flow chart of a nondestructive blood bag plasma chyle index measuring method in an embodiment of the invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail below with reference to embodiments thereof. It should be understood that the detailed description and specific examples, while indicating the scope of the invention, are intended for purposes of illustration only and are not intended to limit the scope of the invention.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not represent the only embodiments.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
The terms "first" and "second" used herein do not denote any particular order or quantity, but rather are used to distinguish one element from another.
As shown in fig. 1, a method for non-destructive measurement of plasma chylomicron index of blood bag in an embodiment of the present invention includes the following steps:
s1, obtaining a first light intensity value I1 of the blood bag after the light source passes through the first thickness value h 1.
S2, obtaining a second light intensity value I2 of the blood bag after the light source passes through the second thickness value h 2.
S3, calculating the chyle index of the plasma according to the first light intensity value I1 and the second light intensity value I2.
Wherein the second thickness value h2 is smaller than the second thickness value h 1.
Because the blood lipid concentration of the blood bag plasma is different at the first thickness value and the second thickness value, the light intensity signals generated by the optical sensor at two times are different, and the blood bag plasma can be obtained according to the Lambert-beer law
Figure BDA0003485538470000041
Or alternatively
Figure BDA0003485538470000042
Wherein epsilonbIs the molar extinction coefficient of blood lipids, cbIs the concentration of blood lipids, AbRepresenting the light attenuation of monochromatic light of the light source caused by plasma with the thickness of h1-h 2. Due to epsilonbAnd h1, h2, thus
Figure BDA0003485538470000043
Or AbConcentration c of feces and blood lipidbIn connection with, AbAnd cbIn a linear relationship.
Assuming that the concentration of blood lipids in normal plasma is cb0According to the standard of GB 18469-2001, it can be known that if the blood plasma to be tested is expressed as 1: n proportion, diluting with colorless transparent normal saline, and changing blood lipid concentration into original one
Figure BDA0003485538470000044
The rear light transmittance is the same as that of normal plasma, and the chyle index of the plasma to be detected is n. It can be deduced from this that, when the blood lipid concentration of the plasma to be measured is (1+ n) cb0When the plasma chylomicron index to be detected is n. Thus, the following relation table of the blood lipid concentration and the chyle index can be obtained.
Blood lipid concentration 2cb0 3cb0 4cb0 5cb0 6cb0 7cb0
Chyle index 1 2 3 4 5 6
Assuming a calibration with plasma having a chyle index of 1, the measured light attenuation was recorded as Ab1Since the light attenuation and the blood fat concentration are in a linear relationship, the following relationship table of the light attenuation and the chyle index can be obtained.
Figure BDA0003485538470000051
From the above table, it can be seen that the light attenuation at an chyle index of n is
Figure BDA0003485538470000052
From this, it can be concluded that the chylomicron index x ═ 2A of the plasmabx/Ab1) -1. Wherein the content of the first and second substances,
Figure BDA0003485538470000053
i3 is the third light intensity value after the light source transmits the plasma with chyle index of 1 at the first thickness value h1, and I4 is the fourth light intensity value after the light source transmits the plasma with chyle index of 1 at the second thickness value h 2.
Regarding the correspondence between chyle index and dilution factor, the following methods are also used in some places: dilution ratio 1: 2 corresponds to a chyle index of 1, a dilution ratio of 1: 4 corresponds to a chyle index of 2, dilution ratio 1: 8 corresponds to a chyle index of 3, dilution ratio 1: 16 corresponds to a chyle index of 4, dilution ratio 1: 32 corresponds to a chyle index of 5, dilution ratio 1: 64 corresponds to a chyle index of 6.
Assuming that the blood lipid concentration in normal plasma is cb0According to the corresponding relationship, the following relationship table of the blood lipid concentration and the 2# chyle index can be obtained.
Blood lipid concentration 3cb0 5cb0 9cb0 17cb0 33cb0 65cb0
Chyle index # 2 1 2 3 4 5 6
Assuming calibration with 2# chyle index 1 plasma, the measured light attenuation was recorded as A2#b1Since the light attenuation and the blood lipid concentration are in a linear relationship, the following relationship table of the light attenuation and the 2# chyle index can be obtained.
Figure BDA0003485538470000061
As can be seen from the above table, the light attenuation of the 2# chyle index is n
Figure BDA0003485538470000062
From this, it can be concluded that the plasma has a 2# chylomicron index x ═ log2((3A2#bx/A2#b1) -1), wherein,
Figure BDA0003485538470000063
i3 is the third light intensity value of the light source after transmitting the plasma with the 2# chyle index of 1 at the first thickness value h1, and I4 is the fourth light intensity value of the light source after transmitting the plasma with the 2# chyle index of 1 at the second thickness value h 2.
In summary, the light transmission characteristic difference of the plasma blood bag when the thickness is different is utilized, and the chyle index of the plasma is calculated according to the first light intensity value and the second light intensity value, the plasma chyle index measurement method of the lossless blood bag does not need to extract the plasma from the blood bag for chyle index measurement, and the problems that the plasma loss and the risk of secondary pollution exist in the existing plasma chyle index measurement method of the blood bag, and partial plasma needs to be extracted from the blood bag for measurement are solved.
In one embodiment, a light intensity signal is generated by the light sensor and converted by the control module into a first light intensity value after the light source has transmitted through the blood bag of the first thickness value h1 and into a second light intensity value after the light source has transmitted through the blood bag of the second thickness value h 2.
In one embodiment, an optical filter is disposed between the blood bag and the light sensor. Specifically, the optical filter is in close contact with the optical sensor. Through the optical filter, light interference outside a light source wave band can be avoided, and the measurement precision of the plasma chyle index of the blood bag is improved.
In one embodiment, the blood bag is positioned between the light source and the light sensor, the light source being a monochromatic light source. Thus, the measurement sensitivity of the plasma chyle index of the blood bag can be improved.
In one embodiment, two sides of the blood bag are respectively attached to the light source and the optical filter (when the optical filter is not included, two sides of the blood bag are respectively attached to the light source and the optical sensor), and the blood bag in the measurement area is filled with plasma without air bubbles, so that the plasma chylomicron index measurement accuracy is improved. The thickness difference between h2 and h1 is obvious, so that the first light intensity value and the second light intensity value obtained by two times of measurement are obviously different, and the chyle index of the plasma is better measured.
A computer-readable storage medium, in which a computer program is stored which, when being executed by a processor, carries out the method of non-destructive blood bag plasma chylomicron index measurement.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (8)

1. A nondestructive measurement method for plasma chyle index of blood bag is characterized by comprising the following steps:
acquiring a first light intensity value I1 of the blood bag of which the light source passes through a first thickness value h 1;
acquiring a second light intensity value I2 of the blood bag of which the light source passes through a second thickness value h 2;
calculating the chyle index of the plasma from the first light intensity value I1 and the second light intensity value I2;
wherein the second thickness value h2 is smaller than the second thickness value h 1.
2. The method for nondestructive measurement of plasma chyle index of blood bag according to claim 1 wherein said plasma chyle index x ═ 2Abx/Ab1) -1, wherein,
Figure FDA0003485538460000011
Figure FDA0003485538460000012
i3 is the third light intensity value after the light source transmits the plasma with the chyme index of 1 at the first thickness value h1, and I4 is the fourth light intensity value after the light source transmits the plasma with the chyme index of 1 at the second thickness value h 2;
wherein, the plasma with chyle index of 1 refers to the ratio of 1: 1 proportion is diluted by colorless transparent normal saline, and the blood fat concentration is changed to the original
Figure FDA0003485538460000013
Plasma with a back transmittance identical to that of normal plasma.
3. The method of claim 2, wherein the plasma chylomicron index x-log is obtained by a non-destructive method2((3A2#bx/A2#b1) -1), wherein,
Figure FDA0003485538460000014
i3 is the third light intensity value after the light source transmits the plasma with the chyme index of 1 at the first thickness value h1, and I4 is the fourth light intensity value after the light source transmits the plasma with the chyme index of 1 at the second thickness value h 2;
wherein, the plasma with chyle index of 1 refers to the ratio of 1: 2 proportion is diluted by colorless transparent normal saline, and the blood fat concentration is changed to the original
Figure FDA0003485538460000015
Plasma with a back transmittance identical to that of normal plasma.
4. The method of claim 3, wherein a light intensity signal is generated by the light sensor, and the control module converts the light intensity signal of the light source after passing through the blood bag with the first thickness value h1 into a first light intensity value and converts the light intensity signal of the light source after passing through the blood bag with the second thickness value h2 into a second light intensity value.
5. The method of claim 4, wherein the blood bag is located between the light source and the light sensor.
6. The method of claim 5, wherein an optical filter is disposed between the blood bag and the optical sensor.
7. The method of claim 6, wherein the light source is a monochromatic light source.
8. A computer-readable storage medium, characterized in that the computer-readable storage medium stores a computer program which, when executed by a processor, implements the non-destructive pouch plasma chylomicron index measuring method according to any one of claims 1-7.
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Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07280814A (en) * 1994-04-14 1995-10-27 Hitachi Ltd Automatic specimen inspection system
US20020167667A1 (en) * 1997-03-03 2002-11-14 James Samsoondar Method and apparatus for measuring analytes in blood bags
US20020186363A1 (en) * 1999-09-03 2002-12-12 James Samsoondar Method and apparatus for screening plasma for interferents in plasma from donor blood bags
CN1560599A (en) * 2004-03-01 2005-01-05 北京市红十字血液中心 Method for investigating blood chylus degree
JP2008026036A (en) * 2006-07-18 2008-02-07 Aloka Co Ltd Inclusion measuring device
CN201993312U (en) * 2011-01-31 2011-09-28 山东省血液中心 Fat blood plasma chyle degree detection device
CA2791004A1 (en) * 2011-09-28 2012-12-07 Aoi Seiki Co., Ltd. Test preprocessing apparatus, test preprocessing method, and specimen processing apparatus
CN103207157A (en) * 2013-04-11 2013-07-17 侯广安 Rapid detection method for severe chylemia
CN105092474A (en) * 2015-08-11 2015-11-25 中山大学 Device and method for measuring extinction coefficient of water body and method for measuring extinction coefficient of suspended matter
CN206563707U (en) * 2017-03-20 2017-10-17 山东省血液中心 Blood plasma chyle interpretoscope and sampled plasma system
CN108760659A (en) * 2018-08-16 2018-11-06 济南希望医疗器械有限公司 It donates blood primary dcreening operation analyzer and its application method
CN109632654A (en) * 2019-01-23 2019-04-16 南方医科大学南方医院 A kind of detection device and its implementation of blood plasma chyle and haemolysis
CN111829962A (en) * 2020-06-28 2020-10-27 中国科学院苏州生物医学工程技术研究所 Plasma chyle degree detection method and system
CN214622293U (en) * 2021-04-09 2021-11-05 深圳市迈思特生物医学工程有限公司 Blood detection device

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07280814A (en) * 1994-04-14 1995-10-27 Hitachi Ltd Automatic specimen inspection system
US20020167667A1 (en) * 1997-03-03 2002-11-14 James Samsoondar Method and apparatus for measuring analytes in blood bags
US20020186363A1 (en) * 1999-09-03 2002-12-12 James Samsoondar Method and apparatus for screening plasma for interferents in plasma from donor blood bags
CN1560599A (en) * 2004-03-01 2005-01-05 北京市红十字血液中心 Method for investigating blood chylus degree
JP2008026036A (en) * 2006-07-18 2008-02-07 Aloka Co Ltd Inclusion measuring device
CN201993312U (en) * 2011-01-31 2011-09-28 山东省血液中心 Fat blood plasma chyle degree detection device
CA2791004A1 (en) * 2011-09-28 2012-12-07 Aoi Seiki Co., Ltd. Test preprocessing apparatus, test preprocessing method, and specimen processing apparatus
CN103207157A (en) * 2013-04-11 2013-07-17 侯广安 Rapid detection method for severe chylemia
CN105092474A (en) * 2015-08-11 2015-11-25 中山大学 Device and method for measuring extinction coefficient of water body and method for measuring extinction coefficient of suspended matter
CN206563707U (en) * 2017-03-20 2017-10-17 山东省血液中心 Blood plasma chyle interpretoscope and sampled plasma system
CN108760659A (en) * 2018-08-16 2018-11-06 济南希望医疗器械有限公司 It donates blood primary dcreening operation analyzer and its application method
CN109632654A (en) * 2019-01-23 2019-04-16 南方医科大学南方医院 A kind of detection device and its implementation of blood plasma chyle and haemolysis
CN111829962A (en) * 2020-06-28 2020-10-27 中国科学院苏州生物医学工程技术研究所 Plasma chyle degree detection method and system
CN214622293U (en) * 2021-04-09 2021-11-05 深圳市迈思特生物医学工程有限公司 Blood detection device

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
M KROISS，ETC: "Association of mitotane with chylomicrons and serum lipoproteins: practical implications for treatment of adrenocortical carcinoma", EUROPEAN JOURNAL OF ENDOCRINOLOGY *
师玉红，等: "吸光度判断乳糜血在4040生化分析仪初筛中的应用", 临床血液学杂志 *
罗怀雪;梁洁贞;卢少芬;陈存意;谭晓颖;曾雪莹;赖建芬;陈馥如;何玉冰;林雪梅;: "低温倒置静置法降低乳糜血浆报废率的研究应用", 中国实用医药 *

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