CN114366893A - Dual cycle carbon dioxide scavenging machine - Google Patents

Dual cycle carbon dioxide scavenging machine Download PDF

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Publication number
CN114366893A
CN114366893A CN202210164590.6A CN202210164590A CN114366893A CN 114366893 A CN114366893 A CN 114366893A CN 202210164590 A CN202210164590 A CN 202210164590A CN 114366893 A CN114366893 A CN 114366893A
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CN
China
Prior art keywords
closed container
carbon dioxide
dialysate
driving pump
hollow fiber
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN202210164590.6A
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Chinese (zh)
Inventor
朱章华
王妍
陈鸣
虞文魁
郭晓芳
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Nanjing Drum Tower Hospital
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Nanjing Drum Tower Hospital
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Publication date
Application filed by Nanjing Drum Tower Hospital filed Critical Nanjing Drum Tower Hospital
Priority to CN202210164590.6A priority Critical patent/CN114366893A/en
Publication of CN114366893A publication Critical patent/CN114366893A/en
Withdrawn legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3666—Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698—Blood oxygenators with or without heat-exchangers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0413—Blood

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

The invention discloses a double-circulation carbon dioxide scavenging machine, which is characterized in that: the device comprises a driving pump, a hollow fiber dialyzer and a closed container, wherein the upper end of the hollow fiber dialyzer is communicated with a blood introducing port through a pipeline and is provided with a driving pump A, and the lower end of the hollow fiber dialyzer is communicated with a blood feedback port through a pipeline; the dialysate outlet and the dialysate inlet of the hollow fiber dialyzer are respectively communicated with the upper end and the lower end of the closed container through pipelines and are provided with driving pumps; the upper end of the closed container is provided with a gas outlet which is connected to the negative pressure pump. The invention solves the problem of low efficiency of removing carbon dioxide in blood and improves the efficiency of removing carbon dioxide in blood; the treatment of clinical II-type respiratory failure is facilitated, the curative effect is improved, and the usage of a tracheal intubation respirator is reduced, so that the treatment comfort and prognosis of a patient are improved; the device has simple principle and structure and strong applicability, and is convenient for popularization, production and use.

Description

Dual cycle carbon dioxide scavenging machine
Technical Field
The invention relates to a carbon dioxide removing device, in particular to a double-circulation carbon dioxide removing machine.
Background
Currently, clinical type II respiratory failure is common, and severe type II respiratory failure requires ventilator support therapy. However, in the ventilator support therapy, especially in the invasive ventilator support therapy, the patient needs tracheal intubation, which is very painful, and usually needs to be assisted by a large amount of anesthetic and sedative drugs, so that the side effects are great. The existing new treatment method is called an Extracorporeal membrane lung Carbon Dioxide Removal technology (ECCO 2R), is similar to the existing leaf-gram membrane (Extracorporeal membrane lung oxygenation, ECMO) which is gradually familiar to the public, is simpler than the leaf-gram membrane, is convenient and has small side effect, utilizes the gas exchange function of the membrane lung to remove the Carbon Dioxide in blood, but has lower efficiency, and only can ensure that a small number of patients avoid the support of a tracheal intubation respirator.
The physicochemical principle that the carbon dioxide removal efficiency is low is that 1. the membrane lung removes gas by using the diffusion effect generated by the pressure difference of the gas at the two sides of the membrane, and the pressure of the carbon dioxide in the blood is not high, so the diffusion efficiency is low; 2. most of the carbon dioxide in blood exists in the form of bicarbonate rather than in a free state, and although bicarbonate and free carbon dioxide can be converted into each other, the efficiency is low in physiological conditions, and the removal efficiency is limited.
Therefore, based on the two important restriction factors, a novel carbon dioxide dialysis device is designed to solve the problem of low carbon dioxide removal efficiency.
Disclosure of Invention
Aiming at the defects in the prior art, the invention provides a double-circulation carbon dioxide scavenging machine to solve the problem of low carbon dioxide scavenging efficiency in blood.
In order to achieve the purpose, the invention adopts the following technical scheme:
the utility model provides a dual cycle carbon dioxide elimination machine which characterized in that: the device comprises a driving pump, a hollow fiber dialyzer and a closed container, wherein the upper end of the hollow fiber dialyzer is communicated with a blood introducing port through a pipeline and is provided with a driving pump A, and the lower end of the hollow fiber dialyzer is communicated with a blood return port through a pipeline; the dialysate outlet of the hollow fiber dialyzer is communicated with the upper end of the closed container through a pipeline and is provided with a driving pump B, and the dialysate inlet of the hollow fiber dialyzer is communicated with the lower end of the closed container through a pipeline and is provided with a driving pump C; and the upper end of the closed container is provided with a gas outlet which is connected to the negative pressure pump.
In order to optimize the technical scheme, the specific measures adopted further comprise:
further, the closed container comprises a temperature control device, and the temperature control device is arranged at the lower end of the closed container.
Further, a stirring device is arranged at the lower end of the inner cavity of the closed container.
Furthermore, an inlet for the dialysate to flow into at the upper end of the closed container is arranged to be a flaring which can make the dialysate flow down along the inner wall of the closed container in a membrane shape.
Further, the flow rate controlled by the driving pump B is equal to that controlled by the driving pump C.
Further, the closed container comprises a weighing device and a control system, the weighing device is used for measuring the weight of the dialysate in the closed container, and the control system is electrically connected with the weighing device, the driving pump B and the driving pump C respectively.
Further, the dialysate adopts macromolecular alkaline dialysate.
The invention has the beneficial effects that:
the invention greatly improves the removal efficiency of carbon dioxide in blood; the treatment of clinical II-type respiratory failure is facilitated, the curative effect is improved, and the usage of a tracheal intubation respirator is reduced, so that the treatment comfort and prognosis of a patient are improved; the device has simple principle and structure and strong applicability, and is convenient for popularization, production and use.
Drawings
Fig. 1 is a schematic structural view of a double circulation carbon dioxide remover.
Reference numerals: 1. the device comprises a driving pump A, a hollow fiber dialyzer, a closed container, a blood introducing port, a blood returning port, a gas outlet, a dialysate inlet, a driving pump B and a driving pump C, wherein the driving pump A is 2, the hollow fiber dialyzer is 3, the closed container is 4, the blood introducing port is 5, the blood returning port is 6, the gas outlet is 7, the dialysate inlet is 8, the driving pump B is 9, and the driving pump C is 10.
Detailed Description
The present invention will now be described in further detail with reference to the accompanying drawings.
It should be noted that the terms "upper", "lower", "left", "right", "front", "back", etc. used in the present invention are for clarity of description only, and are not intended to limit the scope of the present invention, and the relative relationship between the terms and the terms is not limited by the technical contents of the essential changes.
As shown in the attached drawings, the double circulation carbon dioxide remover of the embodiment is characterized in that: the device comprises a driving pump, a hollow fiber dialyzer 2 and a closed container 3, wherein the upper end of the hollow fiber dialyzer 2 is communicated with a blood introducing port 4 through a pipeline, and is provided with a driving pump A1 to assist the flow of blood; the lower end of the hollow fiber dialyzer 2 is communicated with the blood feedback port 5 through a pipeline; the dialysate outlet 7 of the hollow fiber dialyzer 2 is communicated with the upper end of the closed container 3 through a pipeline and is provided with a driving pump B9 to help the flow of dialysate; a dialysate inlet 8 of the hollow fiber dialyzer 2 is communicated with the lower end of the closed container 3 through a pipeline and is provided with a driving pump C10 so as to ensure the circulation of dialysate; the upper end of the closed container 3 is provided with a gas outlet 6, and the gas outlet 6 is connected to a negative pressure pump, so that carbon dioxide dissolved in dialysate overflows under the action of negative pressure and is discharged through the gas outlet 6. Wherein, hollow fiber dialyzer 2 plays the semi-permeable membrane effect, can allow the free passing through of small molecule material, and macromolecular material can not pass through to this realizes that the device operates.
In this embodiment, the closed container 3 includes a temperature control device, the temperature control device is disposed at the lower end of the closed container 3, and the temperature control device heats the dialysate in the closed container 3 to a temperature slightly higher than that of a human body, so that the solubility of carbon dioxide can be reduced by increasing the temperature of water, which is beneficial to discharge carbon dioxide; and the temperature of the dialysate can be increased to prevent heat loss caused by extracorporeal blood circulation, so that hypothermia of a patient is caused, and the hypothermia side effect is relieved.
In this embodiment, a stirring device is provided at the lower end of the inner cavity of the closed container 3, and the discharge of carbon dioxide dissolved in the dialysate can be further promoted.
In this embodiment, the inlet for the dialysate to flow into the upper end of the sealed container 3 is formed as a flare which allows the dialysate to flow down in a film-like manner along the inner wall of the sealed container 3, and further contributes to the escape of carbon dioxide.
In this embodiment, the flow rates controlled by the driving pump B9 and the driving pump C10 are equal, so as to ensure the carbon dioxide removal efficiency and balance of liquid inlet and outlet.
In this embodiment, the closed container 3 includes a weighing device and a control system, the weighing device is used for measuring the weight of the dialysate in the closed container 3, and the control system is electrically connected to the weighing device, the driving pump B9 and the driving pump C10 respectively, so as to adjust the power of the driving pump B9 and the driving pump C10 according to the weight change of the dialysate, so as to prevent the phenomenon of device unbalance or empty pumping of the driving pump caused by too much or too little dialysate in the closed container 3 due to the flow rate difference controlled by the driving pump B9 and the driving pump C10.
In this embodiment, the alkaline dialysate of macromolecule is adopted to the dialysate, can increase the carbon dioxide solubility because of the basicity, increases the dialysate and to the efficiency of ingesting of carbon dioxide in the blood, and the macromolecule is because of the pellicle that can not freely pass through hollow fiber cerini dialyser cerini 2 to avoid disturbing blood pH value.
When the device is used, in the left circulation, blood is led out from the body and passes through the hollow fiber dialyzer 2, and then micromolecular substances including carbon dioxide and the like can be subjected to dispersion exchange with dialysate on the other side of the membrane through the hollow fiber semipermeable membrane of the hollow fiber dialyzer 2, high-concentration carbon dioxide is dispersed and enters the dialysate, the content of carbon dioxide in the blood is reduced, and the carbon dioxide is returned to the body.
In the right side circulation, the dialysate is driven by a driving pump, passes through a hollow fiber dialyzer 2, is subjected to dispersion exchange, then has increased carbon dioxide content, enters a closed container 3, and escapes and is discharged from the dialysate by the action of negative pressure, wherein the carbon dioxide is dissolved in the dialysate; and then, the dialysate with low carbon dioxide content enters the circulation again for exchange, and the circulation is repeated in cycles to achieve the effect of dynamically removing the carbon dioxide in the blood.
The above is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above-mentioned embodiments, and all technical solutions belonging to the idea of the present invention belong to the protection scope of the present invention. It should be noted that modifications and embellishments within the scope of the invention may be made by those skilled in the art without departing from the principle of the invention.

Claims (7)

1. The utility model provides a dual cycle carbon dioxide elimination machine which characterized in that: the device comprises a driving pump, a hollow fiber dialyzer (2) and a closed container (3), wherein the upper end of the hollow fiber dialyzer (2) is communicated with a blood introducing port (4) through a pipeline and is provided with a driving pump A (1), and the lower end of the hollow fiber dialyzer (2) is communicated with a blood feedback port (5) through a pipeline; the dialysate outlet (7) of the hollow fiber dialyzer (2) is communicated with the upper end of the closed container (3) through a pipeline and is provided with a driving pump B (9), and the dialysate inlet (8) of the hollow fiber dialyzer (2) is communicated with the lower end of the closed container (3) through a pipeline and is provided with a driving pump C (10); the upper end of the closed container (3) is provided with a gas outlet (6), and the gas outlet (6) is connected to a negative pressure pump.
2. A dual cycle carbon dioxide scavenger according to claim 1, wherein: the closed container (3) comprises a temperature control device, and the temperature control device is arranged at the lower end of the closed container (3).
3. A dual cycle carbon dioxide remover according to claim 2, wherein: and a stirring device is arranged at the lower end of the inner cavity of the closed container (3).
4. A dual cycle carbon dioxide remover according to claim 3, wherein: the inlet for the dialysate to flow into the upper end of the closed container (3) is set as a flaring which can make the dialysate flow down along the inner wall of the closed container (3) in a film shape.
5. The dual cycle carbon dioxide remover as claimed in claim 4, wherein: the flow rate controlled by the driving pump B (9) is equal to that controlled by the driving pump C (10).
6. A dual cycle carbon dioxide remover according to claim 5, wherein: the closed container (3) comprises a weighing device and a control system, the weighing device is used for measuring the weight of the dialysate in the closed container (3), and the control system is electrically connected with the weighing device, the driving pump B (9) and the driving pump C (10) respectively.
7. A dual cycle carbon dioxide remover according to claim 6, wherein: the dialysate adopts macromolecular alkaline dialysate.
CN202210164590.6A 2022-02-23 2022-02-23 Dual cycle carbon dioxide scavenging machine Withdrawn CN114366893A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210164590.6A CN114366893A (en) 2022-02-23 2022-02-23 Dual cycle carbon dioxide scavenging machine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210164590.6A CN114366893A (en) 2022-02-23 2022-02-23 Dual cycle carbon dioxide scavenging machine

Publications (1)

Publication Number Publication Date
CN114366893A true CN114366893A (en) 2022-04-19

Family

ID=81146601

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210164590.6A Withdrawn CN114366893A (en) 2022-02-23 2022-02-23 Dual cycle carbon dioxide scavenging machine

Country Status (1)

Country Link
CN (1) CN114366893A (en)

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Application publication date: 20220419