CN117398539A - Blood purification device with respiratory support function - Google Patents
Blood purification device with respiratory support function Download PDFInfo
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- CN117398539A CN117398539A CN202311632997.8A CN202311632997A CN117398539A CN 117398539 A CN117398539 A CN 117398539A CN 202311632997 A CN202311632997 A CN 202311632997A CN 117398539 A CN117398539 A CN 117398539A
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- 239000008280 blood Substances 0.000 title claims abstract description 142
- 210000004369 blood Anatomy 0.000 title claims abstract description 142
- 238000000746 purification Methods 0.000 title claims abstract description 33
- 230000000241 respiratory effect Effects 0.000 title claims abstract description 21
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims abstract description 62
- 229910002092 carbon dioxide Inorganic materials 0.000 claims abstract description 31
- 239000001569 carbon dioxide Substances 0.000 claims abstract description 28
- 239000007788 liquid Substances 0.000 claims description 92
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 49
- 239000001301 oxygen Substances 0.000 claims description 49
- 229910052760 oxygen Inorganic materials 0.000 claims description 49
- 238000006467 substitution reaction Methods 0.000 claims description 26
- 238000006073 displacement reaction Methods 0.000 claims description 11
- 239000012530 fluid Substances 0.000 claims description 5
- 238000006213 oxygenation reaction Methods 0.000 abstract description 7
- 239000002699 waste material Substances 0.000 description 17
- 230000006870 function Effects 0.000 description 13
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- 150000002500 ions Chemical class 0.000 description 2
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- 230000029058 respiratory gaseous exchange Effects 0.000 description 2
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- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010018910 Haemolysis Diseases 0.000 description 1
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- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
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- 208000010285 Ventilator-Induced Lung Injury Diseases 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
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- 229910052801 chlorine Inorganic materials 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1698—Blood oxygenators with or without heat-exchangers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3666—Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/04—Liquids
- A61M2202/0413—Blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/18—General characteristics of the apparatus with alarm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/20—Blood composition characteristics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/40—Respiratory characteristics
- A61M2230/43—Composition of exhalation
- A61M2230/432—Composition of exhalation partial CO2 pressure (P-CO2)
Landscapes
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- External Artificial Organs (AREA)
Abstract
The invention provides a blood purification device with a respiratory support function, wherein an oxygenator is arranged on a blood path of the blood purification device, and the oxygenator is arranged on a blood path output pipeline or a blood path input pipeline. The blood purification device can perform extracorporeal oxygenation of blood by using the oxygenator while purifying the blood, remove carbon dioxide in the blood, and provide partial respiratory support function for patients.
Description
Technical Field
The invention relates to the technical field of medical machinery, in particular to blood purification equipment with a respiratory support function.
Background
In vitro carbon dioxide removal (ECCO 2R) is one of the in vitro life support technologies, and the function of replacing lung ventilation by gas exchange is realized by draining blood to an artificial membrane lung (membrane oxygenator), performing oxygenation and CO2 removal, and then reinfusion to the human body. In vitro carbon dioxide removal (ECCO 2R) is mainly used to remove carbon dioxide from patients with acute hypoxia or acute high carbon dioxide respiratory failure to minimize respiratory acidosis and allow more lung protective ventilator settings that can reduce ventilator-induced lung injury. The blood flow of the extracorporeal carbon dioxide removal (ECCO 2R) is relatively low (200-1500 ml/min), CO2 metabolized by a human body can be completely removed, and partial oxygenation capacity can be provided for a patient while CO2 is removed, so that partial respiratory function support of the patient is realized.
Currently, ECMO devices are used clinically to reduce blood flow and use smaller catheters than those used in ECMO for ECCO2R therapy. ECMO devices are expensive, have high consumable costs, typically require a healthcare team to operate, are complex to use, and have very high technical requirements for operators. And reduced centrifugal pump efficiency in ECMO systems can lead to increased blood stagnation and recirculation, which can lead to increased hemolysis, while lower blood flow can also lead to uneven blood flow distribution, blood stagnation through large membrane lungs, need to use higher doses of anticoagulants to avoid thrombosis, and can increase the risk of severe bleeding in patients.
Usually, respiratory failure patients often incorporate other organ failure, and continuous blood purification equipment (CRRT) is required to remove toxins and moisture in the patient and correct internal environment disorder, so that the CRRT equipment and the ECMO equipment are required to be used for treatment for the patient at the same time to realize functional support treatment of a plurality of organs, but the combined use and operation of the two equipment are complex, the treatment cost is high, and safety risks exist.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention aims to provide a blood purifying device with a breathing support function.
In order to achieve the above object, the present invention provides a blood purification apparatus having a respiratory support function, wherein an oxygenator is provided in a blood path of the blood purification apparatus, and the oxygenator is provided in a blood path output line or a blood path input line.
The blood purifying device can purify blood and simultaneously perform extracorporeal oxygenation of the blood by using an oxygenator to remove carbon dioxide in the blood.
In an alternative scheme of the blood purification device with the respiratory support function, a first blood oxygen monitor is arranged on a pipeline in front of a blood inlet end of the oxygenator, a second blood oxygen monitor is arranged on a pipeline behind a blood outlet end of the oxygenator, and blood oxygen signal output ends of the first blood oxygen monitor and the second blood oxygen monitor are respectively connected with a control module of the blood purification device.
In the alternative scheme, the control module can know the oxygenation condition of the blood in real time according to the information fed back by the first blood oxygen monitor and the second blood oxygen monitor sensor.
In an alternative scheme of the blood purification device with the respiratory support function, the device further comprises a percutaneous carbon dioxide monitor, and a carbon dioxide partial pressure signal output end of the percutaneous carbon dioxide monitor is connected with a control module of the blood purification device.
In the alternative scheme, the information fed back by the first blood oxygen monitor, the second blood oxygen monitor sensor and the percutaneous carbon dioxide monitor can be used for evaluating the curative effect by the control module so as to realize the optimal curative effect; and can also be used for judging whether some parts in the blood purifying equipment work normally, such as whether the membrane hole of the oxygenator is blocked.
In an alternative aspect of the blood purification apparatus with respiratory support function, the apparatus further comprises a substitution liquid line and/or a dialysate line;
one end of the replacement liquid pipeline is used for inputting replacement liquid, and the other end of the replacement liquid pipeline is connected to the blood path;
one end of the dialysate pipeline is used for inputting replacement liquid, and the other end of the dialysate pipeline is connected to the dialysate inlet end of the hemofilter of the blood purifying device.
In an alternative aspect of the blood purification apparatus with respiratory support function, the replacement fluid line includes a pre-replacement fluid line and/or a post-replacement fluid line;
one end of the front replacement liquid pipeline is used for inputting replacement liquid, the other end of the front replacement liquid pipeline is connected to the blood pipeline output pipeline, and a front replacement pump is arranged on the front replacement liquid pipeline;
one end of the post-replacement liquid pipeline is used for inputting replacement liquid, the other end of the post-replacement liquid pipeline is connected to the blood path input pipeline, and a post-replacement pump is arranged on the post-replacement liquid pipeline;
and the front displacement pump and the rear displacement pump are respectively in control connection with the control module.
In the alternative scheme, pre-dilution, post-dilution and simultaneous pre-and post-dilution (mixed dilution) can be selected according to clinical requirements, and simultaneously the flow of the replacement liquid of the pre-dilution and the post-dilution can be flexibly carried out according to requirements, so that the service life of the blood filter is prolonged, the treatment metering of a patient is ensured, and the coagulation problem caused by the excessive concentration of blood is reduced.
In an alternative of the respiratory support-equipped blood purification apparatus, the other end of the pre-substitution liquid line is connected to the blood inlet end of the hemofilter.
In an alternative scheme of the blood purifying device with the breathing support function, the blood purifying device further comprises an alarm module connected with the control module.
In an alternative of the blood purification apparatus with respiratory support function, the air inlet of the oxygenator is connected to the oxygen outlet of the oxygen supply device, and the oxygen supply device is connected to the control module in a communication manner.
The beneficial effects of the invention are as follows:
in the process of purifying blood, the invention exchanges gas between blood and externally input oxygen, eliminates a large amount of carbon dioxide in the blood, and realizes the supporting or replacing effect of lung function.
The invention can simultaneously remove toxins such as creatinine, urea nitrogen, inflammatory mediators, cytokines and the like in the body of a patient with renal failure and respiratory failure, and exchange oxygen and carbon dioxide in blood in vitro, and simultaneously realize the substitution of renal and pulmonary functions. Compared with the traditional ECMO, the invention simplifies the treatment scheme, reduces the treatment cost, and has simple operation and safe and reliable treatment process.
Additional aspects and advantages of the invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention.
Drawings
The foregoing and/or additional aspects and advantages of the invention will become apparent and may be better understood from the following description of embodiments taken in conjunction with the accompanying drawings in which:
FIG. 1 is a functional block diagram of the present invention;
fig. 2 is a schematic view of an assembly of the present invention.
Detailed Description
Embodiments of the present invention are described in detail below, examples of which are illustrated in the accompanying drawings, wherein like or similar reference numerals refer to like or similar elements or elements having like or similar functions throughout. The embodiments described below by referring to the drawings are illustrative only and are not to be construed as limiting the invention.
In the description of the present invention, unless otherwise specified and defined, it should be noted that the terms "mounted," "connected," and "coupled" are to be construed broadly, and may be, for example, mechanical or electrical, or may be in communication with each other between two elements, directly or indirectly through intermediaries, as would be understood by those skilled in the art, in view of the specific meaning of the terms described above.
As shown in fig. 1 and 2, the present invention provides a blood purification apparatus having a respiratory support function, in which an oxygenator 4 is provided on a blood path of the blood purification apparatus. In this embodiment, the oxygenator 4 may be a membrane type oxygenator, and may be disposed on a blood output line, as shown in fig. 1, or may be disposed on a blood input line, that is, a line through which blood is returned to the patient end, as shown in fig. 2, and performs in-vitro oxygenation of blood in synchronization with the blood purification process, thereby removing carbon dioxide.
The blood purification apparatus is further provided with a substitution liquid line and a dialysate line 14, one end of the substitution liquid line is inputted with substitution liquid, the other end is connected to the blood path, one end of the dialysate line 14 is inputted with substitution liquid, and the other end is connected to the dialysate inlet end of the hemofilter 6 of the blood purification apparatus. The substitution liquid line may include the pre-substitution liquid line 21 or the post-substitution liquid line 12. As shown in fig. 2, fig. 2 shows a case where the oxygenator 4 is provided in the blood inlet line and only the post-replacement fluid line 12 is provided. In fig. 2, the blood purifying apparatus includes a display 1 and a main body 2, and a blood pump 3, a dialysate pump 16, a post-substitution liquid pump 13, a waste liquid pump 15, a substitution liquid meter 18, and a waste liquid meter 10 are arranged on the front surface of the main body 2.
The blood pump 3 is installed on the arterial line 8, the import of this arterial line 8 is connected with the exit linkage of patient's blood passageway pair, the export of this arterial line 8 is connected with the import of hemofilter 6, hemofilter 6 sets firmly on host computer 2 through holder two 7, the export of hemofilter 6 is connected with the blood import of oxygenator 4 through the pipeline, oxygenator 4 sets firmly on host computer 2 through holder one 5, the air inlet of oxygenator 4 is connected with oxygen, the blood exit linkage of oxygenator 4 has venous line 9, be provided with the venous pot on the venous line 9, the export of patient's central venous catheter is connected to the other end of venous line 9.
The replacement liquid bag 19 is hung on the replacement liquid meter 18, the liquid interface of the replacement liquid bag 19 is connected with the inlet of the post-replacement liquid pipeline 12, the post-replacement liquid pump 13 is arranged on the post-replacement liquid pipeline 12, and the outlet of the post-replacement liquid pipeline 12 is connected with the venous kettle branch pipe of the venous pipeline 9.
The line between the inlet of the post-substitution liquid line 12 and the post-substitution liquid pump 13 is provided with a branch line which is connected to the inlet of the dialysate line 14, the dialysate pump 16 is mounted on the dialysate line 14, and the outlet of the dialysate line 14 is connected to the first joint outside the membrane of the hemofilter 6.
The second joint outside the membrane of the hemofilter 6 is connected with the inlet of a waste liquid pipeline 17, a waste liquid pump 15 is arranged on the waste liquid pipeline 17, the outlet of the waste liquid pipeline 17 is connected with the joint of a waste liquid bag 11, and the waste liquid bag 11 is hung on a waste liquid meter 10.
The blood purifying device leads out the blood of a patient from the outlet of the central venous catheter through the blood pump 3, the blood sequentially passes through the hemofilter 6 and the oxygenator 4, and the blood subjected to substance exchange and gas exchange is finally returned to the human body through the inlet of the central venous catheter, and continuous extracorporeal blood circulation is formed.
The back substitution liquid pump 13 inputs the liquid in the substitution liquid bag 19 into venous blood from a branch pipe on the venous kettle to enter a human body through power; the dialysate pump 16 inputs the liquid in the replacement liquid bag 19 to the outside of the membrane of the hemofilter 6 by power; the waste liquid pump 15 discharges the input dialysate into the waste liquid bag 11 by power, and also discharges part of the moisture in the blood in the hollow fiber membranes of the hemofilter 6 into the waste liquid bag 11 across the membranes. In this process, the speeds of the post-displacement pump 13, the dialysis pump 16 and the waste liquid pump 15 are adjusted by continuously metering the displacement liquid meter 18 and the waste liquid meter 10, so that the liquid output from the displacement liquid bag 19 and the liquid discharged into the waste liquid bag 11 are kept in balance. According to the clinical treatment prescription, if the patient needs to be dehydrated from the body of the renal failure patient, the speeds of the post-displacement pump 13, the dialysis pump 16 and the waste liquid pump 15 are adjusted so that the amount of liquid entering the waste liquid bag 11 per unit time is larger than the amount of liquid discharged from the displacement liquid bag 19, and the difference is the dehydration amount from the body per unit time. The replacement liquid mainly contains ions close to the components of a human body, including potassium, sodium, calcium, chlorine, magnesium, glucose, bicarbonate and other ion components, and can continuously remove a large amount of small molecular toxins in the blood of the human body by utilizing the dispersion and convection principle when the replacement liquid passes through the hemofilter 6, so that the removal of substances such as creatinine, urea nitrogen, inflammatory mediators, cytokines and the like in the body of a patient suffering from renal failure and respiratory failure is realized.
In extracorporeal circulation, when venous blood passes through the oxygenator 4, the venous blood exchanges gas with externally input oxygen to remove a large amount of carbon dioxide in the blood, thereby realizing the supporting or substituting effect of lung function.
In this embodiment, as shown in fig. 1, a first blood oxygen monitor 22 is disposed on a pipeline before the blood inlet end of the oxygenator 4, a second blood oxygen monitor 23 is disposed on a pipeline after the blood outlet end of the oxygenator 4, and blood oxygen signal output ends of the first blood oxygen monitor 22 and the second blood oxygen monitor 23 are respectively connected with a control module of the blood purifying device. The control module can control the blood purification operation and evaluate the oxygenation condition of the blood through the blood oxygen saturation fed back by the first blood oxygen monitor 22 and the second blood oxygen monitor 23.
As shown in fig. 1, a percutaneous carbon dioxide monitor 24 may be further provided, the percutaneous carbon dioxide monitor 24 is attached to the patient, the partial pressure PaCO2 of carbon dioxide in the blood of the patient is measured in real time by the percutaneous carbon dioxide monitor 24, and the output end of the partial pressure signal of carbon dioxide of the percutaneous carbon dioxide monitor 24 is connected with the control module of the blood purifying device. The control module can evaluate the curative effect according to the information fed back by the first blood oxygen monitor 22, the second blood oxygen monitor sensor 23 and the percutaneous carbon dioxide monitor 24, and feed back and adjust parameters such as blood flow, oxygen flow and the like so as to realize the optimal curative effect; meanwhile, whether the oxygenator 4 is blocked by a membrane hole of the oxygenator or not can be analyzed according to the information fed back by the first blood oxygen monitor 22, the second blood oxygen monitor sensor 23 and the percutaneous carbon dioxide monitor 24, so that the gas exchange efficiency is reduced, an operator is prompted to replace corresponding consumable materials in time, and an alarm module is arranged to prompt when in prompting, such as a voice alarm module, and characters and diagrams can be displayed on the display screen 1 to alarm.
In this embodiment, the air inlet of the oxygenator 4 is connected to the oxygen outlet of the oxygen supply device, which may be in communication with the control module. The control module can control the oxygen supply amount of the oxygen supply device according to the information fed back by the first blood oxygen monitor 22, the second blood oxygen monitor sensor 23 and the percutaneous carbon dioxide monitor 24, so that the oxygen supply is always accurate; or the control module sends the information fed back by the first blood oxygen monitor 22, the second blood oxygen monitor sensor 23 and the percutaneous carbon dioxide monitor 24 to the oxygen supply device, and the oxygen supply device automatically adjusts the oxygen supply quantity.
In this embodiment, if the pre-substitution liquid pipeline 21 is required to be provided in the implementation, the pre-substitution liquid pipeline 21 is connected to the blood pipeline at one end, for example, to the blood inlet end of the hemofilter 6, and the pre-substitution pump 20 is provided on the pre-substitution liquid pipeline 21 as shown in fig. 1. The pre-displacement pump 20 and the post-displacement pump 12 are respectively in control connection with the control module. When the front replacement liquid pipeline 21 and the rear replacement liquid pipeline 12 exist at the same time, the front replacement liquid pump 20 and the rear replacement liquid pump 13 can be started at the same time, or only one of them can be started, and the control module can control the start or the stop of the front replacement liquid pump 20 and the rear replacement liquid pump 13 according to actual needs, and the rotating speeds of the front replacement liquid pump 20 and the rear replacement liquid pump 13 are controlled.
In this embodiment, an anticoagulant 25 is also added to the blood path in order to avoid coagulation of the blood.
In the description of the present specification, a description referring to terms "one embodiment," "some embodiments," "examples," "specific examples," or "some examples," etc., means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
While embodiments of the present invention have been shown and described, it will be understood by those of ordinary skill in the art that: many changes, modifications, substitutions and variations may be made to the embodiments without departing from the spirit and principles of the invention, the scope of which is defined by the claims and their equivalents.
Claims (8)
1. A blood purification device with a respiratory support function is characterized in that an oxygenator is arranged on a blood path of the blood purification device, and the oxygenator is arranged on a blood path output pipeline or a blood path input pipeline.
2. The blood purification apparatus with respiratory support function according to claim 1, wherein a first blood oxygen monitor is provided on a line before a blood inlet end of the oxygenator, a second blood oxygen monitor is provided on a line after a blood outlet end of the oxygenator, and blood oxygen signal output ends of the first blood oxygen monitor and the second blood oxygen monitor are respectively connected with a control module of the blood purification apparatus.
3. The respiratory support function equipped blood purification apparatus of claim 1, further comprising a transcutaneous carbon dioxide monitor, wherein the carbon dioxide partial pressure signal output of the transcutaneous carbon dioxide monitor is coupled to the control module of the blood purification apparatus.
4. The respiratory support functional blood purification apparatus of claim 1, further comprising a substitution fluid line and/or a dialysate line;
one end of the replacement liquid pipeline is used for inputting replacement liquid, and the other end of the replacement liquid pipeline is connected to the blood path;
one end of the dialysate pipeline is used for inputting replacement liquid, and the other end of the dialysate pipeline is connected to the dialysate inlet end of the hemofilter of the blood purifying device.
5. The respiratory support blood purification apparatus according to claim 4, wherein the substitution liquid line comprises a pre-substitution liquid line and/or a post-substitution liquid line;
one end of the front replacement liquid pipeline is used for inputting replacement liquid, the other end of the front replacement liquid pipeline is connected to the blood pipeline output pipeline, and a front replacement pump is arranged on the front replacement liquid pipeline;
one end of the post-replacement liquid pipeline is used for inputting replacement liquid, the other end of the post-replacement liquid pipeline is connected to the blood path input pipeline, and a post-replacement pump is arranged on the post-replacement liquid pipeline;
and the front displacement pump and the rear displacement pump are respectively in control connection with the control module.
6. The respiratory support blood purification apparatus according to claim 5, wherein the other end of the pre-substitution liquid line is connected to a blood inlet end of a hemofilter.
7. A blood purification apparatus with respiratory support according to claim 2 or 3, further comprising an alarm module connected to the control module.
8. The blood purification apparatus with respiratory support function according to claim 1, wherein the air inlet of the oxygenator is connected to an oxygen outlet of an oxygen supply device, and the oxygen supply device is communicatively connected to a control module.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311632997.8A CN117398539A (en) | 2023-12-01 | 2023-12-01 | Blood purification device with respiratory support function |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311632997.8A CN117398539A (en) | 2023-12-01 | 2023-12-01 | Blood purification device with respiratory support function |
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| CN117398539A true CN117398539A (en) | 2024-01-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202311632997.8A Pending CN117398539A (en) | 2023-12-01 | 2023-12-01 | Blood purification device with respiratory support function |
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| Country | Link |
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| CN (1) | CN117398539A (en) |
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2023
- 2023-12-01 CN CN202311632997.8A patent/CN117398539A/en active Pending
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