CN111840780B

CN111840780B - Line adapter suitable for blood purification device during ECMO

Info

Publication number: CN111840780B
Application number: CN202010595194.XA
Authority: CN
Inventors: 解启莲; 王昆; 刘欢; 解尧; 余洪龙; 杨东; 李剑; 陈宏凯; 宋泽阳; 徐小菊; 李杨帅
Original assignee: Anhui Tongling Bionic Technology Co Ltd
Current assignee: Anhui Tongling Bionic Technology Co Ltd
Priority date: 2020-06-24
Filing date: 2020-06-24
Publication date: 2022-07-12
Anticipated expiration: 2040-06-24
Also published as: CN111840780A

Abstract

The invention belongs to the technical field of medical instruments, and particularly relates to a pipeline adapter applicable to a blood purification device during ECMO (interstitial-free) periods, which comprises a header pipe and branch pipes, wherein one end of the header pipe is connected to an ECMO drainage pipe, the other end of the header pipe is provided with a shunt valve, the two branch pipes are respectively a first branch pipe and a second branch pipe, and the first branch pipe and the second branch pipe are respectively connected to the shunt valve; the first branch pipe is provided with a first peristaltic pump, the outlet of the first branch pipe is connected to the ECMO oxygenator, the second branch pipe is provided with a second peristaltic pump, and the outlet of the second branch pipe is connected to the CRRT filter; according to the invention, through the organic combination of the diverter valve and the first and second peristaltic pumps, the first branch pipe and the second branch pipe are respectively matched with the requirements of the flow rate and the pressure of the pipeline, particularly the second branch pipe cannot cause high-pressure alarm due to too large flow rate, and a separate flow limiter is not required to change the flow rate, so that the risk of hemolysis and thrombosis is reduced.

Description

Line adapter suitable for blood purification device during ECMO

Technical Field

The invention belongs to the technical field of medical instruments, and particularly relates to a pipeline adapter suitable for a blood purification device during ECMO.

Background

Extracorporeal membrane oxygenation (ECMO) is an extracorporeal life support technology, can replace cardiopulmonary function, provides stable circulating blood volume for patients with cardiopulmonary failure, timely and effectively recovers blood supply and oxygen supply of important organs such as heart and brain, and gains time and opportunity for treatment of critically ill patients. The ECMO system mainly comprises an oxygenator (membrane lung), a centrifugal pump and a pipeline, wherein the pipeline is used as a bridge between the oxygenator and the centrifugal pump and is connected with a patient, specifically, an arteriovenous cannula is connected with a blood vessel of the patient to lead venous blood of the patient out of the body, the venous blood is changed into arterial blood after gas exchange (carbon dioxide discharge and oxygen absorption) is completed by the oxygenator, and then the arterial blood is sent into an arterial system of the patient through the arterial cannula, so that stable circulating blood volume is provided for tissue organs of the patient suffering from cardiopulmonary failure.

Continuous Renal Replacement Therapy (CRRT) refers to blood purification for 24 hours each day to replace the function of the damaged kidney, and has strong blood purification effects by drawing the blood out of the body, removing some metabolic wastes or toxic substances in the blood through the diffusion, convection and adsorption of a filter membrane, and drawing the blood back into the body.

At present, many diseases are not only heart and lung dysfunction but also kidney injury, under the condition, ECMO or CRRT is used alone to be difficult to achieve the purpose of rescuing patients, and ECMO and CRRT are used at the same time under the common condition, but if two blood diversion passages are established for ECMO and CRRT, two groups of wound wounds need to be opened on the body of the patients; and a larger dose of anticoagulation is required during the use of CRRT, so this approach increases patient pain and increases the risk of infection, mechanical injury and difficulty of anticoagulation management. Another concept is to connect the CRRT device with the ECMO device, but it should be noted that the ECMO sends blood into the body to maintain the blood flow of the tissues and organs of the body, and needs to provide great power, so the blood flow rate and pressure in the blood line of the ECMO are high; in normal hemodialysis, the blood flow rate is often slow, because too fast a circuit blood flow update may lead to a blood filter clearing transition on the one hand, and too high a flow pressure may cause a machine arterial pressure to alarm continuously on the other hand. The current conventional method is to add a flow restrictor, but the direct access of the flow restrictor is prone to turbulence, which carries potential hemolysis and thrombus risk.

Disclosure of Invention

In order to overcome the defects existing in the process of using ECMO equipment and CRRT equipment in the prior art, the invention provides a pipeline adapter suitable for a blood purification device in an ECMO period, which can divide blood in an ECMO drainage tube in proportion and respectively convey the blood to an oxygenator and a CRRT filter of ECMO according to different flow rates so as to realize the functions of oxygenating the blood of a patient and purifying the blood.

In order to achieve the purpose, the invention adopts the following technical scheme to realize the purpose:

a line adapter suitable for use in a blood purification apparatus during ECMO, comprising:

one end of the main pipe is connected to the ECMO drainage pipe, and the other end of the main pipe is provided with a shunt valve;

the two branch pipes are respectively a first branch pipe and a second branch pipe, and the first branch pipe and the second branch pipe are respectively connected to the flow dividing valve;

the first branch pipe is provided with a first peristaltic pump, the outlet of the first branch pipe is connected to the ECMO oxygenator, the second branch pipe is provided with a second peristaltic pump, and the outlet of the second branch pipe is connected to the CRRT filter;

and the blood to be oxygenated and purified is led out from the ECMO drainage tube and then respectively enters the first branch tube and the second branch tube through the header tube, and respectively enters the ECMO oxygenator and the CRRT filter under the driving of the first peristaltic pump and the second peristaltic pump.

Preferably, the ratio of the flow rates of the first branch pipe and the second branch pipe is 8: 2.

compared with the prior art, the pipeline adapter provided by the invention has the advantages that the first branch pipe and the second branch pipe are respectively matched with the requirements of the flow rate and the pressure of the pipeline through the organic combination of the flow dividing valve and the first peristaltic pump and the second peristaltic pump, particularly, the second branch pipe does not cause high-pressure alarm due to too large flow rate, a separate flow limiter is not needed for changing the flow rate, and the risk of hemolysis and thrombosis is reduced.

The ECMO equipment and the CRRT equipment are connected by adopting the pipeline adapter provided by the invention, so that the two equipment do not need to be respectively provided with pipes, namely, the two blood diversion passages which are not mutually influenced are prevented from being respectively formed on the body of a patient to construct, the pain of the patient is reduced, and the risks of infection and mechanical injury are reduced.

Additional features and advantages of the invention will be set forth in the detailed description which follows.

Drawings

FIG. 1 is a schematic diagram of a line adapter suitable for use with a blood purification apparatus during ECMO, according to an embodiment of the present invention;

the reference numbers in the figures illustrate: 10-manifold, 11-diverter valve, 20-branch, 21-first branch, 211-first peristaltic pump, 22-second branch, 221-second peristaltic pump, 30-ECMO oxygenator, 40-CRRT filter.

Detailed Description

In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further clarified by combining the specific drawings.

It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. As used herein, the terms "vertical," "horizontal," "left," "right," and the like are for purposes of illustration only and are not intended to represent the only embodiment.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.

As shown in fig. 1, the invention provides a pipeline adapter suitable for a blood purification device during ECMO, which comprises a main pipe 10 and a branch pipe 20, wherein one end of the main pipe 10 is connected to an ECMO drainage pipe, and the ECMO drainage pipe is used for leading blood out of a patient and injecting the blood back into the patient through an arterial cannula after oxygenation is completed; a diverter valve 11 is provided at the other end of the manifold 10. The branch pipes 20 are provided with two branch pipes, namely a first branch pipe 21 and a second branch pipe 22, and the first branch pipe 21 and the second branch pipe 22 are respectively connected to the flow dividing valve 11. Wherein, the first branch pipe 21 is provided with a first peristaltic pump 211, the outlet of the first branch pipe 21 is connected to the ECMO oxygenator 30, the second branch pipe 22 is provided with a second peristaltic pump 221, and the outlet of the second branch pipe 22 is connected to the CRRT filter 40.

The blood to be oxygenated and purified is led out from the ECMO drainage tube, then enters the first branch tube 21 and the second branch tube 22 through the header tube 10, and enters the ECMO oxygenator 30 and the CRRT filter 40 under the driving of the first peristaltic pump 211 and the second peristaltic pump 221.

In the invention, the blood led out from the ECMO drainage tube is divided by the pipeline adapter according to a proportion, and one strand of blood passes through the CRRT filter 40 to realize the purification effect on the blood; the other blood flow passes through an ECMO oxygenator 30 to complete blood oxygenation, carbon dioxide in the blood is exchanged, and fresh oxygen is dissolved; finally, the blood is converged into the body of the patient. Specifically, the shunt valve 11 disposed at the end of the manifold 10 shunts the blood into the first branch tube 21 and the second branch tube 22, and the first peristaltic pump 211 and the second peristaltic pump 221 are used to deliver the blood to the ECMO oxygenator 30 and the CRRT filter 40 according to a certain flow ratio, thereby achieving oxygenation and purification of the blood.

Further, according to the present invention, the ratio of the flow rates of the first branch pipe 21 and the second branch pipe 22 is 8: 2. the first peristaltic pump and the second peristaltic pump provided by the invention are not sensitive to pressure, have very high precision and can accurately control the blood flow of the first branch pipe and the second branch pipe; the first and second peristaltic pumps are used as power sources of the pipeline adapter, and strictly control the blood flow of the first and second branch pipes, so that the blood flow of the second branch pipe 22 flowing into the CRRT filter 40 can be effectively controlled, and the pressure can be obviously reduced, so as to meet the filtering requirements of the CRRT filter 40.

The foregoing shows and describes the general principles, essential features, and inventive features of this invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims

1. A line adapter suitable for use in a blood purification apparatus during ECMO, comprising:

a main pipe (10), one end of which is connected to the ECMO drainage pipe, and the other end of which is provided with a shunt valve (11);

the two branch pipes (20) are respectively a first branch pipe (21) and a second branch pipe (22), the first branch pipe (21) and the second branch pipe (22) are mutually independent, and the first branch pipe (21) and the second branch pipe (22) are respectively connected to the flow dividing valve (11);

wherein a first peristaltic pump (211) is arranged on the first branch pipe (21), the outlet of the first branch pipe (21) is connected to the ECMO oxygenator (30), a second peristaltic pump (221) is arranged on the second branch pipe (22), and the outlet of the second branch pipe (22) is connected to the CRRT filter (40);

the blood to be oxygenated and purified is led out from the ECMO drainage tube, then enters a first branch tube (21) and a second branch tube (22) through the header tube (10) respectively, and enters an ECMO oxygenator (30) and a CRRT filter (40) respectively under the driving of a first peristaltic pump (211) and a second peristaltic pump (221);

the flow rate ratio of the first branch pipe (21) to the second branch pipe (22) is 8: 2.