CN111840780A - Line adapter suitable for blood purification device during ECMO - Google Patents

Line adapter suitable for blood purification device during ECMO Download PDF

Info

Publication number
CN111840780A
CN111840780A CN202010595194.XA CN202010595194A CN111840780A CN 111840780 A CN111840780 A CN 111840780A CN 202010595194 A CN202010595194 A CN 202010595194A CN 111840780 A CN111840780 A CN 111840780A
Authority
CN
China
Prior art keywords
branch pipe
ecmo
branch
pipe
blood
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202010595194.XA
Other languages
Chinese (zh)
Other versions
CN111840780B (en
Inventor
解启莲
王昆
刘欢
解尧
余洪龙
杨东
李剑
陈宏凯
宋泽阳
徐小菊
李杨帅
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anhui Tongling Bionic Technology Co Ltd
Original Assignee
Anhui Tongling Bionic Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anhui Tongling Bionic Technology Co Ltd filed Critical Anhui Tongling Bionic Technology Co Ltd
Priority to CN202010595194.XA priority Critical patent/CN111840780B/en
Publication of CN111840780A publication Critical patent/CN111840780A/en
Application granted granted Critical
Publication of CN111840780B publication Critical patent/CN111840780B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/02—Access sites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/165—Constructional aspects thereof with a dialyser bypass on the dialysis fluid line
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3653—Interfaces between patient blood circulation and extra-corporal blood circuit
    • A61M1/3659—Cannulae pertaining to extracorporeal circulation
    • A61M1/3661—Cannulae pertaining to extracorporeal circulation for haemodialysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M2039/1077—Adapters, e.g. couplings adapting a connector to one or several other connectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention belongs to the technical field of medical instruments, and particularly relates to a pipeline adapter applicable to a blood purification device during ECMO (interstitial-free) periods, which comprises a header pipe and branch pipes, wherein one end of the header pipe is connected to an ECMO drainage pipe, the other end of the header pipe is provided with a shunt valve, the two branch pipes are respectively a first branch pipe and a second branch pipe, and the first branch pipe and the second branch pipe are respectively connected to the shunt valve; the first branch pipe is provided with a first peristaltic pump, the outlet of the first branch pipe is connected to the ECMO oxygenator, the second branch pipe is provided with a second peristaltic pump, and the outlet of the second branch pipe is connected to the CRRT filter; according to the invention, through the organic combination of the diverter valve and the first and second peristaltic pumps, the first branch pipe and the second branch pipe are respectively matched with the requirements of the flow rate and the pressure of the pipeline, particularly the second branch pipe cannot cause high-pressure alarm due to too large flow rate, and a separate flow limiter is not required to change the flow rate, so that the risk of hemolysis and thrombosis is reduced.

Description

Line adapter suitable for blood purification device during ECMO
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a pipeline adapter suitable for a blood purification device during ECMO.
Background
Extracorporeal membrane oxygenation (ECMO) is an extracorporeal life support technology, can replace cardiopulmonary function, provides stable circulating blood volume for patients with cardiopulmonary failure, timely and effectively recovers blood supply and oxygen supply of important organs such as heart, brain and the like, and gains time and opportunity for the treatment of critically ill patients. The ECMO system mainly comprises an oxygenator (membrane lung), a centrifugal pump and a pipeline, wherein the pipeline is used as a bridge between the oxygenator and the centrifugal pump and is connected with a patient, specifically, an arteriovenous cannula is connected with a blood vessel of the patient to lead venous blood of the patient out of the body, the venous blood is changed into arterial blood after gas exchange (carbon dioxide discharge and oxygen absorption) is completed by the oxygenator, and then the arterial blood is sent into an arterial system of the patient through the arterial cannula, so that stable circulating blood volume is provided for tissue organs of the patient suffering from cardiopulmonary failure.
Continuous Renal Replacement Therapy (CRRT) refers to blood purification for 24 hours each day to replace the function of the damaged kidney, and has strong blood purification effects by drawing the blood out of the body, removing some metabolic wastes or toxic substances in the blood through the diffusion, convection and adsorption of a filter membrane, and drawing the blood back into the body.
At present, many diseases, such as viral pneumonia caused by novel coronavirus COVID-19, are not only cardiopulmonary dysfunction, but also accompanied with kidney injury, in such a situation, the purpose of rescuing patients is difficult to achieve by using ECMO or CRRT alone, and ECMO and CRRT are usually used simultaneously, but if two blood diversion passages are established for ECMO and CRRT, two groups of wound are required to be opened on the patients; and a larger dose of anticoagulation is required during the use of CRRT, so this approach increases patient pain and increases the risk of infection, mechanical injury and difficulty of anticoagulation management. Another concept is to connect the CRRT device with the ECMO device, but it should be noted that the ECMO sends blood into the body to maintain the blood flow of the tissues and organs of the body, and needs to provide great power, so the blood flow rate and pressure in the blood line of the ECMO are high; in normal hemodialysis, the blood flow rate is often slow, because too fast a circuit blood flow update may lead to a blood filter clearing transition on the one hand, and too high a flow pressure may cause a machine arterial pressure to alarm continuously on the other hand. The current conventional method is to add a flow restrictor, but the direct access of the flow restrictor is prone to turbulence, which carries potential hemolysis and thrombus risk.
Disclosure of Invention
In order to overcome the defects existing in the process of using ECMO equipment and CRRT equipment in the prior art, the invention provides a pipeline adapter suitable for a blood purification device in an ECMO period, which can divide blood in an ECMO drainage tube in proportion and respectively convey the blood to an oxygenator and a CRRT filter of ECMO according to different flow rates so as to realize the functions of oxygenating the blood of a patient and purifying the blood.
In order to achieve the purpose, the invention adopts the following technical scheme:
a line adapter suitable for use in a blood purification apparatus during ECMO, comprising:
one end of the main pipe is connected to the ECMO drainage pipe, and the other end of the main pipe is provided with a shunt valve;
the two branch pipes are respectively a first branch pipe and a second branch pipe, and the first branch pipe and the second branch pipe are respectively connected to the flow dividing valve;
the first branch pipe is provided with a first peristaltic pump, the outlet of the first branch pipe is connected to the ECMO oxygenator, the second branch pipe is provided with a second peristaltic pump, and the outlet of the second branch pipe is connected to the CRRT filter;
and the blood to be oxygenated and purified is led out from the ECMO drainage tube and then respectively enters the first branch tube and the second branch tube through the header tube, and respectively enters the ECMO oxygenator and the CRRT filter under the driving of the first peristaltic pump and the second peristaltic pump.
Preferably, the ratio of the flow rates of the first branch pipe and the second branch pipe is 8: 2.
compared with the prior art, the pipeline adapter provided by the invention has the advantages that the first branch pipe and the second branch pipe are respectively matched with the requirements of the flow rate and the pressure of the pipeline through the organic combination of the flow dividing valve and the first peristaltic pump and the second peristaltic pump, particularly, the second branch pipe does not cause high-pressure alarm due to too large flow rate, a separate flow limiter is not needed for changing the flow rate, and the risk of hemolysis and thrombosis is reduced.
The ECMO equipment and the CRRT equipment are connected by adopting the pipeline adapter provided by the invention, so that the two equipment do not need to be respectively provided with pipes, namely, the two blood diversion passages which are not mutually influenced are prevented from being respectively formed on the body of a patient to construct, the pain of the patient is reduced, and the risks of infection and mechanical injury are reduced.
Additional features and advantages of the invention will be set forth in the detailed description which follows.
Drawings
FIG. 1 is a schematic diagram of a line adapter suitable for use with a blood purification apparatus during ECMO, according to an embodiment of the present invention;
the reference numbers in the figures illustrate: 10-manifold, 11-diverter valve, 20-branch, 21-first branch, 211-first peristaltic pump, 22-second branch, 221-second peristaltic pump, 30-ECMO oxygenator, 40-CRRT filter.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further clarified by combining the specific drawings.
It will be understood that when an element is referred to as being "secured to" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any and all combinations of one or more of the associated listed items.
As shown in fig. 1, the invention provides a pipeline adapter suitable for a blood purification device during ECMO, which comprises a main pipe 10 and a branch pipe 20, wherein one end of the main pipe 10 is connected to an ECMO drainage pipe, and the ECMO drainage pipe is used for leading blood out of a patient and injecting the blood back into the patient through an arterial cannula after oxygenation is completed; a diverter valve 11 is provided at the other end of the manifold 10. The branch pipes 20 are provided with two branch pipes, namely a first branch pipe 21 and a second branch pipe 22, and the first branch pipe 21 and the second branch pipe 22 are respectively connected to the flow dividing valve 11. Wherein, the first branch pipe 21 is provided with a first peristaltic pump 211, the outlet of the first branch pipe 21 is connected to the ECMO oxygenator 30, the second branch pipe 22 is provided with a second peristaltic pump 221, and the outlet of the second branch pipe 22 is connected to the CRRT filter 40.
The blood to be oxygenated and purified is led out from the ECMO drainage tube, then enters the first branch tube 21 and the second branch tube 22 through the header tube 10, and enters the ECMO oxygenator 30 and the CRRT filter 40 under the driving of the first peristaltic pump 211 and the second peristaltic pump 221.
In the invention, the blood led out from the ECMO drainage tube is divided by the pipeline adapter according to a proportion, and one strand of blood passes through the CRRT filter 40 to realize the purification effect on the blood; the other blood flow passes through an ECMO oxygenator 30 to complete blood oxygenation, carbon dioxide in the blood is exchanged, and fresh oxygen is dissolved; finally, the blood is converged into the body of the patient. Specifically, the shunt valve 11 disposed at the end of the manifold 10 shunts the blood into the first branch tube 21 and the second branch tube 22, and the first peristaltic pump 211 and the second peristaltic pump 221 are used to deliver the blood to the ECMO oxygenator 30 and the CRRT filter 40 according to a certain flow ratio, thereby achieving oxygenation and purification of the blood.
Further, according to the present invention, the ratio of the flow rates of the first branch pipe 21 and the second branch pipe 22 is 8: 2. the first peristaltic pump and the second peristaltic pump provided by the invention are not sensitive to pressure, have very high precision and can accurately control the blood flow of the first branch pipe and the second branch pipe; the first and second peristaltic pumps are used as power sources of the pipeline adapter, and strictly control the blood flow of the first and second branch pipes, so that the blood flow of the second branch pipe 22 flowing into the CRRT filter 40 can be effectively controlled, and the pressure can be obviously reduced, so as to meet the filtering requirements of the CRRT filter 40.
The foregoing shows and describes the general principles, essential features, and inventive features of this invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.

Claims (2)

1. A line adapter suitable for use in a blood purification apparatus during ECMO, comprising:
A main pipe (10), one end of which is connected to the ECMO drainage pipe, and the other end of which is provided with a shunt valve (11);
the two branch pipes (20) are respectively a first branch pipe (21) and a second branch pipe (22), and the first branch pipe (21) and the second branch pipe (22) are respectively connected to the flow dividing valve (11);
wherein a first peristaltic pump (211) is arranged on the first branch pipe (21), the outlet of the first branch pipe (21) is connected to the ECMO oxygenator (30), a second peristaltic pump (221) is arranged on the second branch pipe (22), and the outlet of the second branch pipe (22) is connected to the CRRT filter (40);
the blood to be oxygenated and purified is led out from the ECMO drainage tube, then enters the first branch tube (21) and the second branch tube (22) through the header tube (10) respectively, and enters the ECMO oxygenator (30) and the CRRT filter (40) respectively under the driving of the first peristaltic pump (211) and the second peristaltic pump (221).
2. Line adapter suitable for a blood purification device during ECMO according to claim 1, wherein the ratio of the flow rates of said first branch (21) and second branch (22) is 8: 2.
CN202010595194.XA 2020-06-24 2020-06-24 Line adapter suitable for blood purification device during ECMO Active CN111840780B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202010595194.XA CN111840780B (en) 2020-06-24 2020-06-24 Line adapter suitable for blood purification device during ECMO

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202010595194.XA CN111840780B (en) 2020-06-24 2020-06-24 Line adapter suitable for blood purification device during ECMO

Publications (2)

Publication Number Publication Date
CN111840780A true CN111840780A (en) 2020-10-30
CN111840780B CN111840780B (en) 2022-07-12

Family

ID=72989836

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202010595194.XA Active CN111840780B (en) 2020-06-24 2020-06-24 Line adapter suitable for blood purification device during ECMO

Country Status (1)

Country Link
CN (1) CN111840780B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116439871A (en) * 2023-04-28 2023-07-18 天津大学温州安全(应急)研究院 ECMO experimental device and method for animals

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1378701A (en) * 1971-04-13 1974-12-27 Rhone Poulenc Sa Pressure modulator for and artificial bloodcircuit
US4205042A (en) * 1978-06-23 1980-05-27 Cobe Laboratories, Inc. Blood oxygenator with a gas filter
US20080199357A1 (en) * 2006-12-07 2008-08-21 Levitronix Llc Integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a method of de-bubbling and priming an extracorporeal life support system
CN202376524U (en) * 2011-11-30 2012-08-15 虞文魁 Multifunctional extracorporeal life support and treatment system integrated device
CN103260670A (en) * 2010-10-15 2013-08-21 塞托弗尔克斯股份有限公司 Cytopheresic cartridge and use thereof
CN104800902A (en) * 2015-04-30 2015-07-29 北京迈淩医疗技术发展有限公司 Extracorporeal circulation life supporting device for treating and curing multiple organ failure
US20180344914A1 (en) * 2016-06-06 2018-12-06 The Trustees Of Columbia University In The City Of New York Wearable Ultrafiltration Devices Methods and Systems
CN110072568A (en) * 2016-12-15 2019-07-30 费森尤斯医疗护理德国有限责任公司 For executing blood processor, the blood guide device, blood processing system of extracorporeal blood treatment
CN111135360A (en) * 2020-01-21 2020-05-12 广州弘大医疗科技有限公司 Right heart auxiliary device and control method thereof

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1378701A (en) * 1971-04-13 1974-12-27 Rhone Poulenc Sa Pressure modulator for and artificial bloodcircuit
US4205042A (en) * 1978-06-23 1980-05-27 Cobe Laboratories, Inc. Blood oxygenator with a gas filter
US20080199357A1 (en) * 2006-12-07 2008-08-21 Levitronix Llc Integrated centrifugal blood pump-oxygenator, an extracorporeal life support system and a method of de-bubbling and priming an extracorporeal life support system
CN103260670A (en) * 2010-10-15 2013-08-21 塞托弗尔克斯股份有限公司 Cytopheresic cartridge and use thereof
CN202376524U (en) * 2011-11-30 2012-08-15 虞文魁 Multifunctional extracorporeal life support and treatment system integrated device
CN104800902A (en) * 2015-04-30 2015-07-29 北京迈淩医疗技术发展有限公司 Extracorporeal circulation life supporting device for treating and curing multiple organ failure
US20180344914A1 (en) * 2016-06-06 2018-12-06 The Trustees Of Columbia University In The City Of New York Wearable Ultrafiltration Devices Methods and Systems
CN110072568A (en) * 2016-12-15 2019-07-30 费森尤斯医疗护理德国有限责任公司 For executing blood processor, the blood guide device, blood processing system of extracorporeal blood treatment
CN111135360A (en) * 2020-01-21 2020-05-12 广州弘大医疗科技有限公司 Right heart auxiliary device and control method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116439871A (en) * 2023-04-28 2023-07-18 天津大学温州安全(应急)研究院 ECMO experimental device and method for animals
CN116439871B (en) * 2023-04-28 2024-03-01 天津大学温州安全(应急)研究院 ECMO experimental device and method for animals

Also Published As

Publication number Publication date
CN111840780B (en) 2022-07-12

Similar Documents

Publication Publication Date Title
CA2495459C (en) Selective plasma exchange therapy
US6685664B2 (en) Method and apparatus for ultrafiltration utilizing a long peripheral access venous cannula for blood withdrawal
CN110072569B (en) System for extracorporeal blood treatment, treatment device, kit and method for operating a system for extracorporeal blood treatment
US7942842B2 (en) Apparatus and method for the treatment of blood
CN104800902A (en) Extracorporeal circulation life supporting device for treating and curing multiple organ failure
CN112672678A (en) Wearable modular in vitro life support device for mobile treatment of single and multiple organ failure
Hung et al. Extracorporeal membrane oxygenation: coming to an ICU near you
CN111840780B (en) Line adapter suitable for blood purification device during ECMO
CN112043896A (en) Extracorporeal circulation system
CN114404703B (en) Combined artificial kidney, pre-flushing method and working method thereof
CN214859807U (en) Extracorporeal circulation system
WO2021031433A1 (en) Extracorporeal membrane oxygenation system
CN214679564U (en) Liver support system used in vitro
CN112755288B (en) In-vitro liver support system
US11759559B2 (en) Adjustable shunt pediatric/neonatal ECMO circuit
CN220158875U (en) Continuous blood purifying pipeline
CN219049761U (en) But remote monitoring's dual-purpose blood purification ultrafiltration system of peace warfare
CN212914049U (en) Modular continuous kidney substitution machine
RU2812169C2 (en) Wearable modular device of extracorporeal life-support for mobile treatment of single or multiple organ failure
Ronco et al. The evolving technology for continuous renal replacement therapy from current standards to high-volume hemofiltration
Ronco et al. Nomenclature for continuous renal replacement therapies
CN113521418A (en) Double-filtration adsorption plasma replacement system
CN117398539A (en) Blood purification device with respiratory support function
González-Fernández et al. PROTOCOL OF EXTRACORPOREAL PURIFICATION TECHNIQUES
Wang Blood Purification in the Management of Cardiorenal Organ Failure in Critical Patients with COVID-19 in ICU: A Review

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant