CN114343834A - Pulse ablation control device and pulse ablation system - Google Patents
Pulse ablation control device and pulse ablation system Download PDFInfo
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- CN114343834A CN114343834A CN202111545316.5A CN202111545316A CN114343834A CN 114343834 A CN114343834 A CN 114343834A CN 202111545316 A CN202111545316 A CN 202111545316A CN 114343834 A CN114343834 A CN 114343834A
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Abstract
The embodiment of the specification provides a pulse ablation control device and a pulse ablation system. The control device comprises a power supply module, a high-voltage pulse module and a control module, wherein the power supply module is electrically connected with the high-voltage pulse module and the control module respectively; the control module is used for acquiring pulse electrical parameters corresponding to the target focus and controlling the power supply module and the high-voltage pulse module according to the pulse electrical parameters; the power supply module generates a continuous adjustable electric signal corresponding to the pulse electric parameter and provides the electric signal to the high-voltage pulse module; the high-voltage pulse module converts the electric signal into a high-voltage pulse signal and applies the high-voltage pulse signal to the ablation electrode so as to discharge the target focus for pulse ablation. By generating continuously adjustable pulse voltage, the optimal amplitude voltage according with cell characteristics is output, the operation effect is improved, and the human body injury is reduced.
Description
Technical Field
The specification relates to the technical field of medical equipment, in particular to a pulse ablation control device and a pulse ablation system.
Background
In the modern society, the number of patients suffering from arrhythmia is increasing year by year. High voltage pulse ablation is a commonly used method of treating rapid arrhythmia. The high-voltage pulse ablation method is characterized in that a high-voltage pulse electric field with the pulse width of millisecond, microsecond or even nanosecond is generated, and extremely high energy is released in a short time, so that cell walls are broken, a large number of irreversible micropores are formed, cell sap is lost, focus cell death is realized, and the expected treatment effect is achieved.
According to the cell characteristics and clinical data analysis, the tolerance voltages of cells at different human tissue parts are different, so that the treatment difficulty is brought to pulse ablation, and if the pulse voltage is too low, the ablation treatment is not thorough, and sequelae or other complications are caused; if the pulse voltage is too high, normal cells are damaged, and unnecessary damage is generated.
Disclosure of Invention
In view of this, embodiments of the present disclosure provide a pulse ablation control device and a pulse ablation system, wherein the pulse ablation control device can output a voltage corresponding to an optimal amplitude of cells at different locations, kill focus cells, and avoid damaging normal cells.
The embodiment of the specification provides the following technical scheme:
a pulse ablation control device, comprising: the ablation device comprises a power supply module, a high-voltage pulse module and a control module, wherein the power supply module is respectively and electrically connected with the high-voltage pulse module and the control module;
the control module is used for acquiring a pulse electrical parameter corresponding to a target focus and controlling the power supply module and the high-voltage pulse module according to the pulse electrical parameter;
the power supply module is used for generating a continuously adjustable electric signal corresponding to the pulse electric parameter under the control of the control module and providing the electric signal to the high-voltage pulse module;
the high-voltage pulse module is used for converting the electric signal into a high-voltage pulse signal under the control of the control module and applying the high-voltage pulse signal to the ablation electrode so as to perform pulse ablation on the target focus discharge.
In the scheme, the control module is electrically connected with the power supply module and the high-voltage pulse module respectively for control, pulse parameters are obtained through the control module, and a continuous adjustable electric signal is generated at the power supply module, so that a high-voltage pulse signal is converted and generated at the high-voltage pulse module, the optimal amplitude voltage meeting the requirement of killing focus cells is obtained, the optimal amplitude voltage is accurately released to a focus area, normal cells are prevented from being damaged, the pulse ablation operation effect is improved, and operation damage is reduced.
The embodiment of the present specification further provides a solution, where the power module includes a dc electrical module and an inverter module, the dc electrical module is electrically connected to the inverter module, and the inverter module is electrically connected to the high-voltage pulse module; the control module is electrically connected with the direct current module and the inversion module respectively;
the power module is used for generating a continuously adjustable electric signal corresponding to the pulse electric parameter under the control of the control module and providing the electric signal to the high-voltage pulse module, and comprises:
the direct current module generates a continuous adjustable electric signal corresponding to the pulse electric parameter under the control of the control module, and the inversion module inverts the electric signal and provides the inverted electric signal to the high-voltage pulse module so that the high-voltage pulse module converts the inverted electric signal into a high-voltage pulse signal;
and/or the direct current module provides a continuous electric signal for the inversion module under the control of the control module, the inversion module generates a continuous adjustable electric signal corresponding to the pulse electric parameter after performing inversion and voltage regulation on the continuous electric signal through PWM under the control of the control module, and provides the continuous adjustable electric signal to the high-voltage pulse module, so that the high-voltage pulse module converts the inverted continuous adjustable electric signal into a high-voltage pulse signal.
The embodiment of the present specification further provides a scheme, where the high-voltage pulse module includes a boost module and a rectifier module;
the power supply module is electrically connected with the boosting module, and the boosting module is electrically connected with the rectifying module;
the electric signal is sequentially subjected to voltage modulation by the boosting module, and the rectifying module performs alternating current and direct current conversion to generate the high-voltage pulse signal.
The embodiment of the present specification further provides a scheme, where the high-voltage pulse module further includes a charge pump module, and the charge pump module is electrically connected to the rectification module to store and/or convert high-voltage pulse energy of the high-voltage pulse signal output by the rectification module.
The embodiment of the present specification further provides a scheme, when the number of the ablation electrodes is multiple, the pulse ablation control device further includes a pulse switching module, the high-voltage pulse module is electrically connected to the ablation electrodes through the pulse switching module, and the pulse switching module is electrically connected to the control module;
the high-voltage pulse signal output by the high-voltage pulse module comprises a high-voltage positive pulse and a high-voltage negative pulse, and the pulse switching module is used for outputting the high-voltage positive pulse or the high-voltage negative pulse to the ablation electrode under the control of the control module.
The embodiment of the present specification further provides a solution, where the pulse switching module includes a plurality of switches, and two ends of each switch are electrically connected to one of the ablation electrodes;
the switch is used for outputting high-voltage positive pulses or high-voltage negative pulses to the connected ablation electrode under the control of the control module.
The embodiment of the present specification further provides a scheme, where the control device further includes a data acquisition module, and the data acquisition module is electrically connected to the control module;
the control module is used for acquiring the pulse electrical parameters corresponding to the target focus, and comprises a data acquisition module for acquiring the electrophysiological characteristics of the target focus and transmitting the electrophysiological characteristics to the control module.
The embodiment of the present specification further provides a scheme, where the control module includes a first control unit and a second control unit, and the first control unit and the second control unit are respectively configured to enable the high-voltage pulse module;
the high voltage pulse module is used for applying the high voltage pulse signal to the ablation electrode under the control of the control module, and comprises: the high-voltage pulse module outputs high-voltage positive pulses or high-voltage negative pulses to the connected ablation electrode when the first control unit and the second control unit are enabled simultaneously.
The embodiment of the present specification further provides a scheme that the controller of the first control unit and the controller of the second control unit are different controllers.
The present description also provides a pulse ablation system, an ablation catheter and a pulse ablation control device as described in any one of the preceding, the ablation catheter being connected to the pulse ablation control device.
Compared with the prior art, the beneficial effects that can be achieved by the at least one technical scheme adopted by the embodiment of the specification at least comprise: after the control module obtains the pulse parameter corresponding to the target focus, the power module and the high-voltage pulse module are controlled to enable the power module to generate a continuous adjustable electric signal corresponding to the pulse electric parameter and provide the continuous adjustable electric signal to the high-voltage pulse module, the high-voltage pulse module is converted to generate a high-voltage pulse signal and releases the high-voltage pulse signal to the focus area through an ablation electrode connected with the high-voltage pulse module, so that the optimal amplitude voltage meeting the requirement of killing focus cells is released to the target focus, and meanwhile, normal cells are prevented from being damaged, the pulse ablation control device can obtain any voltage within a set voltage range by generating the continuous adjustable electric signal, the voltage is increased according to multiplying power through the high-voltage pulse module, then the high-voltage pulse electricity is released through the ablation electrode, and the pulse voltage meeting the cell characteristics of the focus area is accurately released, the effect of the pulse ablation operation is improved, the operation efficiency is improved, the damage is reduced, and the safety of the patient is protected.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present application, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
FIG. 1 is a schematic electrical circuit diagram of a pulsed ablation control device;
FIG. 2 is a schematic electrical circuit diagram of a pulsed ablation control device that produces a continuously adjustable electrical signal at the output of a DC module;
FIG. 3 is a schematic circuit diagram of a pulse ablation control device using digital to analog conversion;
FIG. 4 is a schematic circuit diagram of a pulsed ablation control device that generates a continuously adjustable electrical signal at the output of an inverter module;
FIG. 5 is a schematic circuit diagram of a pulse ablation control device including a half-bridge inverter module;
FIG. 6 is a schematic circuit diagram of a pulse ablation control device including a boost module, a rectifier module, and a charge pump module;
FIG. 7 is a schematic circuit diagram of a pulse ablation control device including a pulse switching module;
FIG. 8 is a circuit diagram of a pulse switching module connected to a multi-output circuit;
FIG. 9 is a schematic circuit diagram of a pulsatile ablation control device including a data acquisition module;
FIG. 10 is a circuit schematic of a control module including two independent control units;
10, a control module, 11, a first control unit, 12, a second control unit, 13, a digital-to-analog conversion module, 20, a power module, 21, a first direct current module, 22, a first inversion module, 23, a second direct current module, 24, a second inversion module, 241, a half-bridge inversion module, 25, a direct current module, 26, an inversion module, 30, a high-voltage pulse module, 31, a boosting module, 32, a rectification module, 33, a charge pump module, 40, a pulse switching module, 50, a data acquisition module, 60 and an ablation electrode.
Detailed Description
The embodiments of the present application will be described in detail below with reference to the accompanying drawings.
The following description of the embodiments of the present application is provided by way of specific examples, and other advantages and effects of the present application will be readily apparent to those skilled in the art from the disclosure herein. It is to be understood that the embodiments described are only a few embodiments of the present application and not all embodiments. The present application is capable of other and different embodiments and its several details are capable of modifications and/or changes in various respects, all without departing from the spirit of the present application. It is to be noted that the features in the following embodiments and examples may be combined with each other without conflict. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.
It is noted that various aspects of the embodiments are described below within the scope of the appended claims. It should be apparent that the aspects described herein may be embodied in a wide variety of forms and that any specific structure and/or function described herein is merely illustrative. Based on the present application, one skilled in the art should appreciate that one aspect described herein may be implemented independently of any other aspects and that two or more of these aspects may be combined in various ways. For example, an apparatus may be implemented and/or a method practiced using any number and aspects set forth herein. Additionally, such an apparatus may be implemented and/or such a method may be practiced using other structure and/or functionality in addition to one or more of the aspects set forth herein.
It should be noted that the drawings provided in the following embodiments are only for illustrating the basic idea of the present application, and the drawings only show the components related to the present application rather than the number, shape and size of the components in actual implementation, and the type, amount and ratio of the components in actual implementation may be changed arbitrarily, and the layout of the components may be more complicated.
In addition, in the following description, specific details are provided to facilitate a thorough understanding of the examples. However, it will be understood by those skilled in the art that the aspects may be practiced without these specific details.
The cardiac pulse electric field ablation is an ablation mode using a pulse field as energy, has preferential selectivity on myocardial tissues, utilizes non-thermal energy ablation, has the characteristics of instantaneous energy release, difficulty in damaging adjacent tissues and organs and the like, and is increasingly concerned. The high-voltage pulse ablation is to generate a high-voltage pulse electric field with the pulse width of millisecond, microsecond or even nanosecond, and release extremely high energy in a short time, so that cell walls are broken, a large number of irreversible micropores are formed, cell sap is lost, focus cell death is realized, and the expected treatment effect is achieved.
Research and analysis on cell characteristics and clinical research data show that the cell tolerance voltage parameters of different human tissue positions are different, and in order to achieve a good treatment effect, the voltage with the optimal amplitude is required to be output according to different cell characteristic voltages to kill cells in a focus area, and meanwhile, the healthy cells are not greatly influenced.
Based on the clinical requirements and technical characteristics, the inventor provides a pulse ablation control system capable of being continuously adjusted in an output voltage range, a low-voltage power supply module is electrically connected with a high-voltage pulse module, the control module is used for managing the modules, pulse electrical parameters of a focus area are collected through a control device, the low-voltage power supply module is controlled according to the pulse electrical parameters, a continuously adjustable electrical signal is output, the high-voltage pulse module is used for multiplying the electrical signal and releasing the electrical signal to the focus area, and therefore the output voltage of high-voltage pulse is continuously adjusted, the characteristics of cells in different focus areas are met, and the optimal amplitude voltage meeting the requirement of ablating the cells in the area is output.
The technical solutions provided by the embodiments of the present application are described below with reference to the accompanying drawings.
The pulse ablation control device shown in fig. 1 comprises a power supply module 20, a high-voltage pulse module 30 and a control module 10, wherein the power supply module 20 is electrically connected with the high-voltage pulse module 30 and the control module 10 respectively, the high-voltage pulse module 30 is electrically connected with the control module 10, and the high-voltage pulse module 30 is electrically connected with an ablation electrode 60. The control module 10 performs two operations, including the control module 10 obtaining a pulse electrical parameter corresponding to the target lesion, and controlling the power module 20 and the high voltage pulse module 30 according to the pulse electrical parameter, where it should be noted that the two operations of the control module 10 may be a continuous operation mode or a circulating operation mode. It should be noted that the manner of acquiring the pulse electrical parameter of the target lesion may include a direct measurement manner, such as acquiring the cell resistance of the lesion region, or may also include an indirect measurement manner, such as acquiring the current and/or voltage of the ablation electrode, and the specific acquisition manner is not limited herein. The power module 20 is configured to generate a continuously adjustable electrical signal corresponding to the pulse electrical parameter under the control of the control module 10, and provide the electrical signal to the high voltage pulse module 30. The high voltage pulse module 30 is configured to convert the electrical signal into a high voltage pulse signal under the control of the control module 10, for example, increase the voltage by using a voltage transformation method or a capacitive energy storage method, apply the high voltage pulse signal to the ablation electrode 60, release energy through the ablation electrode, and discharge the target lesion for pulse ablation.
The control module controls the power supply module and the high-voltage pulse module according to the pulse electrical parameters of the target focus, the high-voltage pulse module converts the electrical signals into high-voltage pulse signals by generating continuously adjustable electrical signals at the power supply module, then the high-voltage pulse with continuously adjustable output voltage is generated, the optimal amplitude voltage which accords with the ablation of cells in the region is output through the ablation electrode, a good treatment effect is achieved, and normal cells are prevented from being damaged.
In some embodiments, as shown in fig. 2, the power module 20 includes a first dc module 21 and a first inverter module 22, the first dc module 21 is electrically connected to the first inverter module 22, the first inverter module 22 is electrically connected to the high-voltage pulse module 30, and the control module 10 is electrically connected to the first dc module 21 and the first inverter module 22, respectively. Under the control of the control module 10, the first dc power module 21 generates the continuously adjustable electrical signal corresponding to the pulse electrical parameter, and the first inversion module 22 inverts the electrical signal and then provides the inverted electrical signal to the high-voltage pulse module 30, so that the high-voltage pulse module 30 converts the inverted electrical signal into a high-voltage pulse signal.
Optionally, the communication interface of the control module 10 is connected to the feedback end of the first dc module 21, so that the output voltage of the first dc module 21 is continuously adjustable.
For example, as shown in fig. 3, the input voltage of the first dc module 21 is 48V, the communication interface of the control module 10 is an SPI serial bus, the SPI serial bus is electrically connected to the digital-to-analog conversion module 13 (i.e., DAC module), and the digital-to-analog conversion module 13 is connected to the feedback end of the first dc module 21, so that the output voltage of the first dc module 21 is continuously adjustable in the range of 0 to 45V.
Optionally, the first inverter module 22 includes a half-bridge inverter circuit or a full-bridge inverter circuit.
In some embodiments, as shown in fig. 4, the power module 20 includes a second dc module 23 and a second inverter module 24, the second dc module 23 is electrically connected to the second inverter module 24, the second inverter module 24 is electrically connected to the high voltage pulse module 30, the control module 10 is electrically connected to the second dc module 23 and the second inverter module 24, the second dc module 23 generates a continuous electrical signal under the control of the control module 30, and the second inverter module 24 generates a continuously adjustable electrical signal corresponding to the pulse electrical parameter after performing inversion and voltage adjustment on the continuous electrical signal through PWM under the control of the control module 10 and provides the continuous adjustable electrical signal to the high voltage pulse module 30, so that the high voltage pulse module 30 converts the continuous adjustable electrical signal into a high voltage pulse signal.
Optionally, the second inverter module 24 includes a half-bridge inverter circuit or a full-bridge inverter circuit.
Optionally, the output voltage of the second inverter module 24 is continuously adjustable by controlling the switching frequency of the second inverter module 24.
For example, as shown in fig. 5, the second inverter module 24 is a half-bridge inverter module 241, that is, the power module 20 includes a second dc module 23 and a half-bridge inverter module 241, the second dc module 23 is electrically connected to the half-bridge inverter module 241, the half-bridge inverter module 241 is electrically connected to the high-voltage pulse module 30, the control module 10 is electrically connected to the second dc module 23 and the half-bridge inverter module 241, and the output voltage of the half-bridge inverter module 241 can be continuously adjusted by changing the duty ratio of the PWM signal sent to the half-bridge inverter module 241 by the control module 10.
In some embodiments, as shown in fig. 6, the high-voltage pulse module includes a boosting module 31 and a rectifying module 32, the dc module 25 is electrically connected to the inverting module 26, the inverting module 26 is electrically connected to the boosting module 31, the boosting module 31 is electrically connected to the rectifying module 32, the control module 10 is electrically connected to the dc module 25 and the inverting module 26, an output end of the inverting module 26 may output an electrical signal with continuously adjustable voltage, and a manner of generating the electrical signal with continuously adjustable voltage may refer to the foregoing embodiments, which is not described herein again. The electric signal with continuously adjustable voltage sequentially passes through the boosting module 31 to modulate the voltage, the rectifying module 32 performs alternating current and direct current conversion to generate a high-voltage pulse signal, and the high-voltage pulse signal is released through the ablation electrode to perform ablation treatment.
Preferably, as shown in fig. 6, the high voltage pulse module 30 further includes a charge pump module 33, and the charge pump module 33 is electrically connected to the rectifying module 32 to store and/or convert the high voltage pulse energy of the high voltage pulse signal output by the rectifying module 32.
It should be noted that the control module 10 may electrically connect any one or more of the boosting module 31, the rectifying module 32, and the charge pump module 33 according to a control requirement, for example: the control module 10 is electrically connected with the boosting module 31 (not shown in the figure); alternatively, the control module 10 is electrically connected to the charge pump module 33 (as shown in fig. 6) to control the charge pump module 33 to discharge the pulse energy; alternatively, the control module 10 is electrically connected to the rectifying module 32 and the charge pump module 33, respectively.
Optionally, the boosting module 31 includes a transformer, a bootstrap circuit, and the like.
Optionally, the rectification module 32 includes a half-wave rectification circuit, a full-wave bridge rectification circuit, and the like.
Optionally, the charge pump module 33 includes a switching regulator boost pump, a non-regulation capacitor type charge pump, and a regulation capacitor type charge pump.
In some embodiments, the pulse ablation device has multiple ablation electrodes, for example, the distal end of an ablation catheter is provided with a ring member on which multiple ablation electrodes are disposed for delivering pulse ablation energy, in which case the pulse ablation control apparatus further includes a pulse switching die 40 that, in combination with the multiple ablation electrodes, is capable of delivering positive or negative pulses on the different electrodes.
As shown in fig. 7, the high voltage pulse module 30 is electrically connected to the pulse switching module 40, the pulse switching module 40 is electrically connected to the ablation electrode 60, the control module 10 is electrically connected to the pulse switching module 40, and the pulse switching module 40 is configured to output a high voltage positive pulse and/or a high voltage negative pulse to the ablation electrode 60 under the control of the control module 10.
It should be noted that the high voltage pulse module 30 can also output a high voltage positive pulse and a high voltage negative pulse under the control of the control module 10, for example, the control module 10 is electrically connected to the charge pump module 33, and outputs the high voltage positive pulse and/or the high voltage negative pulse by controlling the charge pump module 33, for example: two separate charge pump circuits are used, wherein a first positive high-voltage charge pump is used for generating positive high voltage, a second negative high-voltage charge pump is used for generating negative high voltage, the working conditions of the two charge pump circuits are controlled by the control module 10, and high-voltage positive pulse and/or high-voltage negative pulse are/is output. The charge pump module with two independent charge pump circuits is electrically connected with the pulse switching module, the control module is configured to be electrically connected with the charge pump module and the pulse switching module respectively, and the pulse output mode on the ablation electrode can be configured more flexibly through the management of the control module.
In some embodiments, as shown in fig. 8, the pulse switching module 40 includes a plurality of switches, and both ends of each switch are electrically connected to one of the ablation electrodes;
the switch is used for outputting high-voltage positive pulses or high-voltage negative pulses to the connected ablation electrodes under the control of the control module 10.
Preferably, the switch is a single-pole double-throw relay, as shown in fig. 8, and with this type of relay, positive and negative pulse outputs between any two or more output electrodes can be realized, as shown in fig. 8, the pulse switching module 40 connects the high-voltage positive pulse circuit and the high-voltage negative pulse circuit, and a multi-output circuit (i.e. OUT in fig. 8) is arranged between the high-voltage positive pulse circuit and the high-voltage negative pulse circuit1To OUTn) Each circuit is sequentially connected with a relay A in seriesnAblation electrode and relay Bn. At this time, if the relay A is used1Connecting high-voltage positive pulse, relay B5High-voltage negative pulse is connected, the rest relays are connected with a suspension end, and the pulse switching module 40 is arranged on an output circuit OUT1And OUT5High-voltage positive pulses are output; if the relay B is connected1Connecting high-voltage negative pulse, relay A2High-voltage positive pulse is connected, the rest relays are connected with a suspension end, and the pulse switching module 40 is arranged on an output circuit OUT1And OUT2High-voltage negative pulses are output; if the relay A is used1And relay A3Connecting high-voltage positive pulse, relay B1And relay B4High-voltage negative pulse is connected, the rest relays are connected with a suspension end, and the pulse switching module 40 is arranged on an output circuit OUT1And OUT3Between, OUT2And OUT4While simultaneously outputting high voltage positive pulses.
In some embodiments, the pulse ablation control device shown in fig. 9 further comprises a data acquisition module 50, the data acquisition module 50 is electrically connected to the control module 10, and the data acquisition module 50 is configured to acquire the electrophysiological characteristics of the target lesion and transmit the electrophysiological characteristics to the control module 10.
Optionally, the acquiring electrophysiological characteristics of the target lesion comprises: by using the mapping catheter, the data acquisition module 50 directly acquires the current value and/or voltage value of the target lesion; electrically connecting the data acquisition module 50 with the ablation electrode 60, and acquiring a current value and/or a voltage value on the ablation electrode attached to the target focus; the data acquisition module 50 is electrically connected to the pulse switching module 40, and acquires a feedback current value and/or a voltage value on the pulse switching module 40.
The electrophysiological characteristics of a target focus are collected through the data collection module, measurement data can be fed back to the control module in time, the control module calculates impedance characteristic data of focus cells through a built-in or external calculation method according to the measurement data, the control module adjusts the output voltage of the power supply module in time according to the impedance characteristic data, pulses with the optimal amplitude value according with the impedance characteristics of the focus cells are output through the high-voltage pulse module, effective ablation of the focus cells and protection of normal cells are achieved, and the treatment effect is improved.
In some embodiments, as shown in fig. 10, the control module 10 includes a first control unit 11 and a second control unit 12, the first control unit 11 and the second control unit 12 are respectively connected to the high voltage pulse module 30 and are capable of respectively enabling the high voltage pulse module 30, and when the high voltage pulse module 30 is simultaneously enabled at the first control unit 11 and the second control unit 12, a high voltage positive pulse or a high voltage negative pulse is output to the connected ablation electrode 60.
The pulse voltage that uses in the pulse ablation operation is high, uses kilovolt rank pulse electric field more, through set up the control unit that two control high-voltage pulse module enabled in the control unit, only when two control unit enable simultaneously, just can allow to release high-voltage pulse, prevents that the condition of unexpected release pulse from taking place, protection patient safety and operation safety.
Preferably, the first control unit 11 and the second control unit 12 are different controllers. For example: the first control unit 11 is a field programmable gate array type (FPGA) chip; the second control unit 12 is a Micro Control Unit (MCU). Further, the pulse width is controlled by an FPGA chip; the MCU is used for controlling the pulse number, and the pulse width and the pulse number are independently controlled, so that better stability is provided for a control system. Similarly, the FPGA chip and the MCU may be connected to the high voltage pulse module 30, and only when both the FPGA chip and the MCU are enabled, the high voltage pulse module 30 can output the high voltage positive pulse or the high voltage negative pulse.
Based on the same inventive concept, embodiments of the present specification further provide a pulse ablation system, which includes an ablation catheter and the pulse ablation control device described in any one of the preceding claims, wherein the ablation catheter is connected with the pulse ablation control device.
The embodiments in the present specification are described in a progressive manner, and the same and similar parts among the embodiments can be referred to each other, and each embodiment focuses on the differences from the other embodiments. In particular, for the method embodiments described later, since they correspond to the system, the description is simple, and for the relevant points, reference may be made to the partial description of the system embodiments.
The above description is only for the specific embodiments of the present application, but the scope of the present application is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present application should be covered within the scope of the present application. Therefore, the protection scope of the present application shall be subject to the protection scope of the claims.
Claims (10)
1. A pulse ablation control device, comprising: the ablation device comprises a power supply module, a high-voltage pulse module and a control module, wherein the power supply module is respectively and electrically connected with the high-voltage pulse module and the control module;
the control module is used for acquiring a pulse electrical parameter corresponding to a target focus and controlling the power supply module and the high-voltage pulse module according to the pulse electrical parameter;
the power supply module is used for generating a continuously adjustable electric signal corresponding to the pulse electric parameter under the control of the control module and providing the electric signal to the high-voltage pulse module;
the high-voltage pulse module is used for converting the electric signal into a high-voltage pulse signal under the control of the control module and applying the high-voltage pulse signal to the ablation electrode so as to perform pulse ablation on the target focus discharge.
2. The pulse ablation control device according to claim 1, wherein the power module comprises a dc module and an inverter module, the dc module is electrically connected to the inverter module, and the inverter module is electrically connected to the high voltage pulse module; the control module is electrically connected with the direct current module and the inversion module respectively;
the power module is used for generating a continuously adjustable electric signal corresponding to the pulse electric parameter under the control of the control module and providing the electric signal to the high-voltage pulse module, and comprises:
the direct current module generates a continuous adjustable electric signal corresponding to the pulse electric parameter under the control of the control module, and the inversion module inverts the electric signal and provides the inverted electric signal to the high-voltage pulse module so that the high-voltage pulse module converts the inverted electric signal into a high-voltage pulse signal;
and/or the direct current module provides a continuous electric signal for the inversion module under the control of the control module, the inversion module generates a continuous adjustable electric signal corresponding to the pulse electric parameter after performing inversion and voltage regulation on the continuous electric signal through PWM under the control of the control module, and provides the continuous adjustable electric signal to the high-voltage pulse module, so that the high-voltage pulse module converts the inverted continuous adjustable electric signal into a high-voltage pulse signal.
3. The pulse ablation control device according to claim 1, wherein the high voltage pulse module comprises a boost module and a rectifier module;
the power supply module is electrically connected with the boosting module, and the boosting module is electrically connected with the rectifying module;
the electric signals sequentially pass through the boosting module for boosting, and the rectifying module generates the electric signals output by the boosting module into the high-voltage pulse signals.
4. The pulse ablation control device according to claim 3, wherein the high-voltage pulse module further comprises a charge pump module, and the charge pump module is electrically connected with the rectification module to store and/or transform high-voltage pulse energy of the high-voltage pulse signal output by the rectification module.
5. The pulse ablation control device according to claim 1, further comprising a pulse switching module, when the ablation electrode is plural, through which the high-voltage pulse module is electrically connected with the ablation electrode, the pulse switching module being electrically connected with the control module;
the high-voltage pulse signal output by the high-voltage pulse module comprises a high-voltage positive pulse and a high-voltage negative pulse, and the pulse switching module is used for outputting the high-voltage positive pulse or the high-voltage negative pulse to the ablation electrode under the control of the control module.
6. The pulse ablation control device according to claim 5, wherein the pulse switching module comprises a plurality of switches, and two ends of each switch are electrically connected with one ablation electrode;
the switch is used for outputting high-voltage positive pulses or high-voltage negative pulses to the connected ablation electrode under the control of the control module.
7. The pulse ablation control device according to claim 1, further comprising a data acquisition module electrically connected to the control module;
the control module is used for acquiring the pulse electrical parameters corresponding to the target focus, and comprises a data acquisition module for acquiring the electrophysiological characteristics of the target focus and transmitting the electrophysiological characteristics to the control module.
8. The pulse ablation control device according to claim 1, wherein the control module comprises a first control unit and a second control unit, the first control unit and the second control unit being respectively used for enabling the high voltage pulse module;
the high voltage pulse module is used for applying the high voltage pulse signal to the ablation electrode under the control of the control module, and comprises: the high-voltage pulse module outputs high-voltage positive pulses or high-voltage negative pulses to the connected ablation electrode when the first control unit and the second control unit are enabled simultaneously.
9. The pulse ablation control device of claim 8, wherein the controller of the first control unit and the controller of the second control unit are different controllers.
10. A pulse ablation system comprising an ablation catheter and a pulse ablation control device as claimed in any one of claims 1 to 9, said ablation catheter being connected to said pulse ablation control device.
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| CN115005961A (en) * | 2022-07-07 | 2022-09-06 | 上海普实医疗器械股份有限公司 | Cardiac pulse electric field ablation system |
| CN116458993A (en) * | 2023-04-19 | 2023-07-21 | 上海玮启医疗器械有限公司 | Pulse ablation control system |
| US11786300B2 (en) | 2021-04-07 | 2023-10-17 | Btl Medical Technologies S.R.O. | Pulsed field ablation device and method |
| US11896298B2 (en) | 2021-07-06 | 2024-02-13 | Btl Medical Development A.S. | Pulsed field ablation device and method |
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| CN114343834B (en) | 2023-04-28 |
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