CN219439389U - Pulsed electric field therapeutic device - Google Patents

Pulsed electric field therapeutic device Download PDF

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Publication number
CN219439389U
CN219439389U CN202222254974.5U CN202222254974U CN219439389U CN 219439389 U CN219439389 U CN 219439389U CN 202222254974 U CN202222254974 U CN 202222254974U CN 219439389 U CN219439389 U CN 219439389U
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module
pulse
signal
foot switch
power supply
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董守龙
姚陈果
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Chongqing University
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Chongqing University
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Abstract

The utility model discloses a pulse electric field treatment device, which comprises a computer control module, a programmable control acquisition module, a pulse forming module, an output switching module, an electrode group, an isolation and power supply module and a high-voltage direct current power supply module, wherein the computer control module is connected with the programmable control acquisition module; the utility model provides a pulse electric field treatment device, which can realize the purposes of reducing muscle contraction, enhancing biomedical effect and the like by flexibly adjusting the amplitude, pulse width, polarity and the like of pulse parameters.

Description

Pulsed electric field therapeutic device
Technical Field
The utility model relates to the field of tissue ablation, in particular to a pulsed electric field treatment device.
Background
The pulsed electric field tissue ablation technology is to release high-voltage electric pulses to biological tissues through electrode needles, so that the aim of tissue ablation is fulfilled. Its main tissue ablation principle includes:
1. the high voltage pulsed electric field alters membrane structure permeability in cells, including cell membranes, mitochondrial membranes, golgi apparatus, nuclear membranes, etc., disrupting cellular homeostasis, causing cell necrosis.
2. The high-voltage pulse electric field acts on the inside of cells to form an internal electric treatment effect, and causes biomedical effects such as apoptosis, pyrosis and the like, so that the cells die, cell fragments after death can be phagocytized by phagocytes in the body, and simultaneously, the immune response of the body occurs, so that the effect of controlling tumors is achieved.
Animal experiments and cell experimental studies show that the field intensity amplitude of the electric pulse is related to the cell biomedical effect (electroporation, irreversible electroporation, internal electrical treatment effect, etc.) caused by the electric pulse.
Therefore, in order to enhance the biomedical effect of cells, a pulsed electric field generating device that can flexibly adjust the pulse parameters is needed.
Disclosure of Invention
The utility model aims to provide a pulse electric field treatment device which comprises a computer control module, a programmable control acquisition module, a pulse forming module, an output switching module, an electrode group, an isolation and power supply module and a high-voltage direct current power supply module, wherein the computer control module is connected with the programmable control acquisition module;
the isolation and power supply module receives external alternating current and further supplies power to the computer control module, the programmable control acquisition module and the high-voltage direct current power supply module;
the high-voltage direct-current power supply module converts the electric signal transmitted by the isolation and power supply module into a direct-current voltage signal with adjustable amplitude and transmits the direct-current voltage signal to the pulse forming module and the output switching module;
the computer control module generates pulse parameter adjustment data and transmits the pulse parameter adjustment data to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal;
the programmable control acquisition module transmits the pulse control signal to the pulse forming module and transmits the output switching signal to the output switching module;
the pulse forming module transmits pulse signals to the electrode through the output switching module;
the output switching module transmits pulse signals to part or all of the electrodes in the electrode group;
the electrodes receiving the pulse signals electrically stimulate the target area.
Further, the system also comprises an external control module;
the external control function module comprises an external trigger function module and a foot switch;
the external triggering function module receives a synchronous control signal transmitted by external equipment and transmits the synchronous control signal to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal;
the foot switch generates a foot switch action signal and transmits the foot switch action signal to the programmable control acquisition module; the foot switch action signals comprise foot switch trigger action signals and foot switch release action signals;
the foot switch action signal is a foot switch trigger action signal, and the pulse forming module transmits a pulse signal to the electrode through the output switching module;
the foot switch action signal is a foot switch loosening action signal, and the pulse forming module only applies the pulse signal to the internal load Rint of the switching module, and does not transmit the pulse signal to the electrode.
Further, the power supply filter is also included;
the power filter filters the electric signals output by the isolation and power supply module.
Further, the pulse forming module outputs pulse signals with adjustable amplitude, pulse width, polarity and number.
Further, the device also comprises a measuring circuit;
the measuring circuit monitors real-time pulse parameters output by the pulse forming module and feeds the real-time pulse parameters back to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and outputs a switching signal.
Further, a discharge circuit is also included;
the discharging circuit is used for discharging the electric energy stored in the pulse forming module.
Further, the device also comprises a foot switch circuit and an isolation device;
the foot switch circuit is used for receiving foot switch action signals generated by foot switches and transmitting the foot switch action signals to the programmable control acquisition module through the isolation device;
further, the pulse forming module comprises a bipolar multi-level pulse generating circuit and a unipolar multi-level pulse generating circuit.
Further, the emergency stop switch is included;
the emergency stop switch is used for closing the pulse electric field treatment device.
Further, a display for displaying the pulse operation state is included.
The utility model has the technical effects that the pulse electric field treatment device is undoubtedly provided, and the device can flexibly adjust the amplitude, the pulse width, the polarity and the like of pulse parameters, thereby being beneficial to achieving the purposes of reducing muscle contraction, enhancing biomedical effects and the like.
Drawings
FIG. 1 is a block diagram of a pulsed electric field therapy device;
FIG. 2 is a schematic diagram of a foot switch control;
FIG. 3 is a bipolar multi-level pulse generation circuit;
fig. 4 is a unipolar multi-level pulse generation circuit.
Detailed Description
The present utility model is further described below with reference to examples, but it should not be construed that the scope of the above subject matter of the present utility model is limited to the following examples. Various substitutions and alterations are made according to the ordinary skill and familiar means of the art without departing from the technical spirit of the utility model, and all such substitutions and alterations are intended to be included in the scope of the utility model.
Example 1:
referring to fig. 1 to 4, a pulsed electric field therapeutic apparatus includes a computer control module, a programmable control acquisition module, a pulse forming module, an output switching module, an electrode group, an isolation and power supply module, a high voltage direct current power supply module, an external control module, a power filter, a measurement circuit, a discharge circuit, a foot switch circuit, an isolation device, a scram switch, and a display for displaying the running state of the pulse;
the isolation and power supply module receives external alternating current and further supplies power to the computer control module, the programmable control acquisition module and the high-voltage direct current power supply module;
the high-voltage direct-current power supply module converts the electric signal transmitted by the isolation and power supply module into a direct-current voltage signal with adjustable amplitude and transmits the direct-current voltage signal to the pulse forming module and the output switching module;
the computer control module generates pulse parameter adjustment data and transmits the pulse parameter adjustment data to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal according to the pulse parameter adjustment data;
the programmable control acquisition module transmits the pulse control signal to the pulse forming module and transmits the output switching signal to the output switching module;
the pulse forming module transmits pulse signals to the electrode through the output switching module;
the output switching module transmits pulse signals to part or all of the electrodes in the electrode group according to the output switching signals;
the electrodes receiving the pulse signals electrically stimulate the target area.
The external control function module comprises an external trigger function module and a foot switch;
the external triggering function module receives a synchronous control signal transmitted by external equipment and transmits the synchronous control signal to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal;
the foot switch generates a foot switch action signal and transmits the foot switch action signal to the programmable control acquisition module; the foot switch action signals comprise foot switch trigger action signals and foot switch release action signals;
the foot switch action signal is a foot switch trigger action signal, and the pulse forming module transmits a pulse signal to the electrode through the output switching module;
the foot switch action signal is a foot switch loosening action signal, and the pulse forming module only applies the pulse signal to the internal load Rint of the switching module, and does not transmit the pulse signal to the electrode.
The power filter filters the electric signals output by the isolation and power supply module.
The pulse forming module outputs pulse signals with adjustable amplitude, pulse width, polarity and number.
The measuring circuit monitors real-time pulse parameters output by the pulse forming module and feeds the real-time pulse parameters back to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and outputs a switching signal.
The discharging circuit is used for discharging the electric energy stored in the pulse forming module.
The foot switch circuit is used for receiving foot switch action signals generated by foot switches and transmitting the foot switch action signals to the programmable control acquisition module through the isolation device;
the pulse forming module comprises a bipolar multi-level pulse generating circuit and a unipolar multi-level pulse generating circuit.
The emergency stop switch is used for closing the pulse electric field treatment device.
Example 2:
a pulse electric field treatment device comprises a computer control module, a programmable control acquisition module, a pulse forming module, an output switching module, an electrode group, an isolation and power supply module and a high-voltage direct current power supply module;
the isolation and power supply module receives external alternating current and further supplies power to the computer control module, the programmable control acquisition module and the high-voltage direct current power supply module;
the high-voltage direct-current power supply module converts the electric signal transmitted by the isolation and power supply module into a direct-current voltage signal with adjustable amplitude and transmits the direct-current voltage signal to the pulse forming module and the output switching module;
the computer control module generates pulse parameter adjustment data and transmits the pulse parameter adjustment data to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal according to the pulse parameter adjustment data;
the programmable control acquisition module transmits the pulse control signal to the pulse forming module and transmits the output switching signal to the output switching module;
the pulse forming module transmits pulse signals to the electrode through the output switching module;
the output switching module transmits pulse signals to part or all of the electrodes in the electrode group according to the output switching signals;
the electrodes receiving the pulse signals electrically stimulate the target area.
Example 3:
the main content of the pulsed electric field treatment device is as shown in embodiment 2, wherein the pulsed electric field treatment device further comprises an external control module;
the external control function module comprises an external trigger function module and a foot switch;
the external triggering function module receives a synchronous control signal transmitted by external equipment and transmits the synchronous control signal to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal;
the foot switch generates a foot switch action signal and transmits the foot switch action signal to the programmable control acquisition module; the foot switch action signals comprise foot switch trigger action signals and foot switch release action signals;
the foot switch action signal is a foot switch trigger action signal, and the pulse forming module transmits a pulse signal to the electrode through the output switching module;
the foot switch action signal is a foot switch loosening action signal, and the pulse forming module only applies the pulse signal to the internal load Rint of the switching module, and does not transmit the pulse signal to the electrode.
Example 4:
a pulsed electric field treatment apparatus, the main content of which is described in embodiment 2, further comprising a power filter;
the power filter filters the electric signals output by the isolation and power supply module.
Example 5:
the main content of the pulsed electric field treatment device is as in embodiment 2, wherein the pulse forming module outputs pulse signals with adjustable amplitude, pulse width, polarity and number.
Example 6:
a pulsed electric field treatment apparatus, the main content of which is described in embodiment 2, further comprising a measurement circuit;
the measuring circuit monitors real-time pulse parameters output by the pulse forming module and feeds the real-time pulse parameters back to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and outputs a switching signal.
Example 7:
a pulsed electric field treatment apparatus, the main content of which is shown in embodiment 2, further comprising a discharge circuit;
the discharging circuit is used for discharging the electric energy stored in the pulse forming module.
Example 8:
a pulsed electric field therapeutic apparatus, the main content of which is shown in embodiment 2, further comprises a foot switch circuit and an isolation device;
the foot switch circuit is used for receiving foot switch action signals generated by foot switches and transmitting the foot switch action signals to the programmable control acquisition module through the isolation device;
example 9:
the main content of the pulsed electric field treatment device is as in embodiment 2, wherein the pulse forming module comprises a bipolar multi-level pulse generating circuit and a unipolar multi-level pulse generating circuit.
Example 10:
the main content of the pulsed electric field treatment device is as shown in the embodiment 2, wherein the pulsed electric field treatment device further comprises an emergency stop switch;
the emergency stop switch is used for closing the pulse electric field treatment device.
Example 11:
a pulsed electric field therapy apparatus, the main content of which is as in embodiment 2, further comprising a display for displaying the running state of the pulses.
Example 12:
a pulse electric field treatment device comprises a computer control module, a programmable control acquisition module, a pulse forming module, an output switching module, an electrode group, an isolation and power supply module and a high-voltage direct current power supply module;
the isolation and power supply module receives external alternating current and further supplies power to the computer control module, the programmable control acquisition module and the high-voltage direct current power supply module;
the high-voltage direct-current power supply module converts the electric signal transmitted by the isolation and power supply module into a direct-current voltage signal with adjustable amplitude and transmits the direct-current voltage signal to the pulse forming module and the output switching module;
the computer control module generates pulse parameter adjustment data and transmits the pulse parameter adjustment data to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal according to the pulse parameter adjustment data;
the programmable control acquisition module transmits the pulse control signal to the pulse forming module and transmits the output switching signal to the output switching module;
the pulse forming module transmits pulse signals to the electrode through the output switching module;
the output switching module transmits pulse signals to part or all of the electrodes in the electrode group according to the output switching signals;
the electrode receiving the pulse signal performs electrical stimulation to the target area.
The pulsed electric field therapy device further comprises an external control module;
the external control function module comprises an external trigger function module and a foot switch;
the external triggering function module receives a synchronous control signal transmitted by external equipment and transmits the synchronous control signal to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal according to the synchronous control signal and the pulse parameter adjustment data;
the foot switch generates a foot switch action signal and transmits the foot switch action signal to the programmable control acquisition module; the foot switch action signals comprise foot switch trigger action signals and foot switch release action signals;
when the programmable control acquisition module receives a foot switch trigger action signal, the pulse forming module transmits a pulse signal to the electrode through the output switching module;
when the programmable control acquisition module receives the foot switch loosening action signal, the pulse forming module only applies the pulse signal to the internal load Rint of the switching module, and does not transmit the pulse signal to the electrode.
Specifically, the foot switch is controlled as follows:
when the foot switch is stepped down (for example, the signal is 1), the programmable control module receives a foot switch stepping instruction (for example, when the signal is 1), the programmable control module sends out an instruction to control the relay 0 to be conducted (as shown in the following diagram), and then the relay 0 is conducted. The high voltage pulse generated by the pulse forming module is transmitted to the following 12 relays (output switching module). Then 12 relays in the switching module are output, and 6 electrode pins are independently connected with a positive wire or a negative wire through on/off.
When the foot switch is released (for example, the signal is 0), the programmable control module receives a foot switch release instruction (for example, when the signal is 0), the programmable control module sends out an instruction to control the relay 0 to be opened (as shown in the following diagram), and then the relay 0 is opened. The high voltage pulse generated by the pulse forming module will be applied only to the internal load Rint of the switching module.
The pulsed electric field treatment device further comprises a power filter;
the power filter filters the electric signals output by the isolation and power supply module.
The pulse forming module outputs pulse signals with adjustable amplitude, pulse width, polarity and number.
The pulsed electric field therapy device further comprises a measurement circuit;
the measuring circuit monitors real-time pulse parameters output by the pulse forming module and feeds the real-time pulse parameters back to the programmable control acquisition module;
and the programmable control acquisition module generates a pulse control signal and an output switching signal according to the real-time pulse parameters.
The pulsed electric field therapy device further comprises a discharge circuit;
the discharging circuit is used for discharging the electric energy stored in the pulse forming module.
The pulse electric field treatment device also comprises a foot switch circuit and an isolation device;
the foot switch circuit is used for receiving foot switch action signals generated by foot switches and programmable control the acquisition module through the isolation device;
the pulse forming module comprises a bipolar multi-level pulse generating circuit.
The pulse forming module comprises a power supply module, a first pulse forming module, a second pulse forming module and a load;
the power supply module supplies power to the first pulse forming module and the second pulse forming module;
the first pulse forming module comprises n first pulse generating units; the integer n is more than or equal to 2;
the second pulse forming module comprises m second pulse generating units; the integer m is more than or equal to 2;
the first pulse forming module and the second pulse forming module are respectively connected in series at two ends of the load, and electric pulses are applied to the two ends of the load.
The power supply module comprises at least two first power supply units and at least two second power supply units;
the two first power supply units are a first high-voltage power supply unit and a first low-voltage power supply unit respectively;
the first high-voltage power supply unit and the first low-voltage power supply unit respectively supply power to different first pulse generation units in the first pulse formation module;
the two second power supply units are respectively a second high-voltage power supply unit and a second low-voltage power supply unit;
the second high-voltage power supply unit and the second low-voltage power supply unit respectively supply power to different second pulse generating units in the first pulse forming module.
The power supply module comprises n first power supply units and m second power supply units;
among the n first power supply units, n1 first power supply units are first high-voltage power supply units, and n2 first power supply units are first low-voltage power supply units; n1+n2=n;
the ith first power supply unit supplies power to the ith first pulse generation unit; i=1, 2, …, n;
among the m second power supply units, m1 second power supply units are second high-voltage power supply units, and m2 second power supply units are second low-voltage power supply units; m1+m2=m;
the j second power supply unit supplies power to the j second pulse generation unit; j=1, 2, …, m.
The circuit topology of the ith first pulse generation unit is as follows:
the first end of the isolation device IPi-1 is connected with the end where the positive electrode of the power supply module is located, and the second end is connected with the capacitor CPi-1 in series and then grounded; the second end of the isolation device IPi-1 is connected with the second end of the switch SPI-1 after being connected with the capacitor CPi-1 in series; i=1, 2, …, n;
the second end of the isolation device IPi-1 is connected with the first end of the switch SPI-1 in series, and the second end of the switch SPI-1 is connected with the first end of the switch SPI-1 in series; the second end of the switch SPi-1 is grounded;
the second end of the isolation device IPi-1 is connected with the second end of the switch SPI-2 after being connected with the switch SPI-1 in series;
the second end of the isolation device IPi-1 is connected with the first end of the isolation device IPi-2 in series;
the first end of the isolation device IPi-g is connected with the second end of the isolation device IPi- (g-1) in series, and the second end is connected with the second end of the switch SPI-g after being connected with the capacitor CPi-g in series; g=2, …, x; g. x is an integer;
the second end of the isolation device IPi-g is connected with the first end of the switch SPI-g in series, and the second end of the switch SPI-g is connected with the first end of the switch SPI-g in series;
the second end of the isolation device IPi-g is connected with the second end of the switch SPI- (g+1) after the switch SPI-g is connected in series;
the second end of the switch SPi-x is connected with the second end of the capacitor CP (i+1) -1 in series;
the second terminal of switch SPi-x is connected in series with the second terminal of switch SP (i+1) -1.
The circuit topology of the j-th second pulse generating unit is as follows:
the first end of the isolation device INj-1 is connected with the end where the positive electrode of the power supply module is positioned, and the second end is connected with the capacitor CNj-1 in series and then grounded; the second end of the isolation device INj-1 is connected in series with the capacitor CNj-1 and then connected to the second end of the switch SNj-1; j=1, 2, …, m;
the second terminal of isolation device INj-1 is connected in series with the first terminal of switch SNj-1, and the second terminal of switch SNj-1 is connected in series with the first terminal of switch SNj-1; the second terminal of switch SNj-1 is grounded;
the second terminal of the isolation device INj-1 is connected in series with the second terminal of the switch SNj-1 and then connected to the second terminal of the switch SNj-2;
the second end of isolation device INj-1 is connected in series with the first end of isolation device INj-2;
the first end of the isolation device INj-g is connected in series with the second end of the isolation device INj- (g-1), and the second end is connected in series with the second end of the switch SNj-g after the capacitor CNj-g; g=2, …, x; g. x is an integer;
the second terminal of isolation device INj-g is connected in series with the first terminal of switch SNj-g, and the second terminal of switch SNj-g is connected in series with the first terminal of switch SNj-g;
the second terminal of isolation device INj-g is connected in series with second terminal of switch SNj-g and then switch SNj- (g+1);
a second terminal of the switch SNj-x is connected in series with a second terminal of the capacitor CN (j+1) -1;
the second terminal of switch SNj-x is connected in series with the second terminal of switch SN (j+1) -1.
The pulsed electric field treatment device also comprises an emergency stop switch;
the emergency stop switch is used for closing the pulse electric field treatment device.
The pulsed electric field therapy device further comprises a display for displaying the status of the pulsed operation.
Example 13:
referring to fig. 1,2 and 4, a pulsed electric field therapeutic apparatus includes a computer control module, a programmable control acquisition module, a pulse forming module, an output switching module, an electrode group, an isolation and power supply module, and a high voltage dc power supply module;
the isolation and power supply module receives external alternating current and further supplies power to the computer control module, the programmable control acquisition module and the high-voltage direct current power supply module;
the high-voltage direct-current power supply module converts the electric signal transmitted by the isolation and power supply module into a direct-current voltage signal with adjustable amplitude and transmits the direct-current voltage signal to the pulse forming module and the output switching module;
the computer control module generates pulse parameter adjustment data and transmits the pulse parameter adjustment data to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal according to the pulse parameter adjustment data;
the programmable control acquisition module transmits the pulse control signal to the pulse forming module and transmits the output switching signal to the output switching module;
the pulse forming module transmits pulse signals to the electrode through the output switching module;
the output switching module transmits pulse signals to part or all of the electrodes in the electrode group according to the output switching signals;
the electrode receiving the pulse signal performs electrical stimulation to the target area.
The pulsed electric field therapy device further comprises an external control module;
the external control function module comprises an external trigger function module and a foot switch;
the external triggering function module receives a synchronous control signal transmitted by external equipment and transmits the synchronous control signal to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal according to the synchronous control signal and the pulse parameter adjustment data;
the foot switch generates a foot switch action signal and transmits the foot switch action signal to the programmable control acquisition module; the foot switch action signals comprise foot switch trigger action signals and foot switch release action signals;
when the programmable control acquisition module receives a foot switch trigger action signal, the pulse forming module transmits a pulse signal to the electrode through the output switching module;
when the programmable control acquisition module receives the foot switch loosening action signal, the pulse forming module only applies the pulse signal to the internal load Rint of the switching module, and does not transmit the pulse signal to the electrode.
Specifically, the foot switch is controlled as follows:
when the foot switch is stepped down (for example, the signal is 1), the programmable control module receives a foot switch stepping instruction (for example, when the signal is 1), the programmable control module sends out an instruction to control the relay 0 to be conducted (as shown in the following diagram), and then the relay 0 is conducted. The high voltage pulse generated by the pulse forming module is transmitted to the following 12 relays (output switching module). Then 12 relays in the switching module are output, and 6 electrode pins are independently connected with a positive wire or a negative wire through on/off.
When the foot switch is released (for example, the signal is 0), the programmable control module receives a foot switch release instruction (for example, when the signal is 0), the programmable control module sends out an instruction to control the relay 0 to be opened (as shown in the following diagram), and then the relay 0 is opened. The high voltage pulse generated by the pulse forming module will be applied only to the internal load Rint of the switching module.
The pulsed electric field treatment device further comprises a power filter;
the power filter filters the electric signals output by the isolation and power supply module.
The pulse forming module outputs pulse signals with adjustable amplitude, pulse width, polarity and number.
The pulsed electric field therapy device further comprises a measurement circuit;
the measuring circuit monitors real-time pulse parameters output by the pulse forming module and feeds the real-time pulse parameters back to the programmable control acquisition module;
and the programmable control acquisition module generates a pulse control signal and an output switching signal according to the real-time pulse parameters.
The pulsed electric field therapy device further comprises a discharge circuit;
the discharging circuit is used for discharging the electric energy stored in the pulse forming module.
The pulse electric field treatment device also comprises a foot switch circuit and an isolation device;
the foot switch circuit is used for receiving foot switch action signals generated by foot switches and programmable control the acquisition module through the isolation device;
the pulse forming module comprises a unipolar multi-level pulse generating circuit.
The pulse forming module comprises a power supply module and a pulse forming module;
the power supply module supplies power to the pulse forming module;
the pulse forming module comprises n pulse generating units; the integer n is more than or equal to 2;
the pulse forming module applies an electrical pulse across a load. The pulse forming module at least comprises a high-voltage pulse generating unit and a low-voltage pulse generating unit.
The power supply module comprises n power supply units;
among the n power supply units, n1 power supply units are high-voltage power supply units, and n2 power supply units are low-voltage power supply units; n1+n2=n;
the ith power supply unit supplies power to the ith pulse generation unit; i=1, 2, …, n;
the circuit topology of the pulse forming module is as follows:
the anode of the diode INL1 is connected in series with one end of the low-voltage power supply unit LVDC1, and the other end of the low-voltage power supply unit LVDC1 is grounded;
the cathode of the diode INL1 is connected in series with the anode of the diode INL 2;
the cathode of the diode INL1 is connected with the capacitor CNL1 in series and then grounded; the cathode of the diode INL1 is connected with the switches SNL1, SNL1 in series and then grounded;
the anode of diode INLj is connected in series with the cathode of diode INL (j-1), and the cathode is connected in series with the anode of diode INL (j+1); j=2, 3, …, m; m is an integer;
the cathode of the diode INLj is connected with the second end of the switch SNL (j+1) after being connected with the capacitor CNLj in series;
the cathode of the diode INLm is connected in series with the switch SNLm and then connected with the second end of the switch SNH 1;
the anode of the diode INH1 is connected in series with one end of the anode of the high-voltage power supply unit HVDC1, and the other end of the cathode of the high-voltage power supply unit HVDC1 is grounded;
the cathode of the diode INH1 is connected in series with the anode of the diode INH 2;
the cathode of the diode INH1 is connected in series with the capacitor CNH1 and then connected to the second end of the switch SNH 1; the cathode of the diode INH1 is connected with the capacitor CNH1 after being connected with the switches SNH1 and SNH1 in series;
the anode of the diode INHk is connected in series with the cathode of the diode INH (k-1), and the cathode is connected in series with the anode of the diode INH (k+1); k=2, 3, …, f; f is an integer;
the cathode of the diode INHk is connected with the second end of the switch SNH (k+1) after being connected with the capacitor CNHk in series;
the cathode of the diode INH f is connected in series with the switch SNH f and the load RL and then grounded.
Example 14:
a pulsed electric field therapeutic device comprises the following components:
the pulse parameter control system has the advantages that the pulse parameter control system is provided with the computer control module and the programmable control acquisition module, can realize the accurate control of the pulse parameter, is provided with a friendly man-machine interaction interface, and can accurately control the pulse parameter through the computer display by a user and display the pulse running state of the treatment device.
The pulse synchronous control device has an external trigger function, can be connected with external equipment, and can synchronously control and output pulses.
The pulse output control device is provided with a foot switch, and a user can realize pulse output control by stepping on the foot switch.
The power supply filter, the isolation and power supply module are arranged, so that the filtering of the power supply alternating current can be realized, the protection isolation is realized, and the power supply is performed on other modules.
The high-voltage direct-current power supply module can convert alternating-current commercial power into adjustable direct current so as to supply power for the pulse forming module.
The pulse forming module is provided for converting the direct current of the high-voltage direct current power supply module into high-voltage pulses with adjustable parameters such as amplitude, pulse width, polarity and the like.
The high-voltage pulse generator is provided with an output switching module, and can switch and output the high-voltage pulse generated by the pulse forming module to the electrode needle interface, so that the switching and outputting of the high-voltage pulse by a plurality of electrode needles are realized.
The high-voltage pulse parameter measuring circuit is provided with a measuring circuit, and can measure the high-voltage pulse parameter generated by the pulse forming module and feed back the high-voltage pulse parameter to the programmable acquisition module.
A discharge circuit is provided to discharge the electrical energy stored in the pulse forming module when the treatment is completed or the output is discontinued.
Example 15:
a pulsed electric field therapy device, comprising: the device comprises a display, a computer host, a programmable control acquisition module, an external trigger function, a foot switch, a module with a power filter, an isolation and power supply module, a high-voltage direct-current power supply module, a pulse forming module, an output switching module, a measuring circuit, a discharging circuit and the like.
The host computer can be a notebook computer, a desktop computer, a microcomputer, an industrial personal computer and the like.
The programmable control module can be a programmable chip such as a singlechip, an ARM microprocessor, an FPGA and the like and an accessory circuit, and can control and measure the electrical parameters in the circuit.
The external trigger circuit can receive external trigger signals and transmit the external trigger signals to the programmable control acquisition module through isolating devices such as optical fibers, optocouplers, small transformers and the like.
The foot switch circuit can receive external foot switch action signals and transmit the signals to the programmable control acquisition module through isolating devices such as optical fibers, optocouplers, small transformers and the like.
The power filter can filter the AC mains supply and is also provided with a switch, a fuse and other devices, so that safe and reliable electric energy is provided for the treatment system.
The isolation and power supply module comprises an isolation transformer, can isolate alternating current, has the function of converting alternating current into direct current, and can provide alternating current and direct current power for other modules.
The high-voltage direct-current power supply module can supply alternating current or direct current into direct current with adjustable amplitude, so as to provide electric energy for the pulse forming module.
The pulse forming module internally comprises energy storage elements (capacitors, inductors and the like), switches and other elements and circuits, electric energy in the energy storage elements can be converted into high-voltage pulses through switching of the switches, the polarity of the high-voltage pulses can be unipolar or bipolar, the waveform can be square waves, triangular waves, trapezoidal waves, exponential waves and the like, the pulse amplitude is adjustable, and the output frequency and the number are adjustable.
The measuring circuit comprises current measuring and voltage measuring functions, and can measure high-voltage pulse parameters in the pulse forming module and transmit the high-voltage pulse parameters to the programmable control acquisition module.
And the discharging circuit can release the energy stored in the pulse forming module when the treatment device stops running or stops running.
The output switching module comprises a plurality of switches (relays, IGBTs, MOSFETs and the like), and can switch the pulse of the pulse forming module to a plurality of electrode interfaces, wherein the number of the electrode pin interfaces is more than or equal to 2.
The emergency stop switch can be pressed in an emergency mode to stop pulse output when the device fails or the treatment process is abnormal.
The control system switch can control the computer to be turned on or off.

Claims (10)

1. A pulsed electric field therapy device, characterized by: the device comprises a computer control module, a programmable control acquisition module, a pulse forming module, an output switching module, an electrode group, an isolation and power supply module and a high-voltage direct-current power supply module;
the isolation and power supply module receives external alternating current and further supplies power to the computer control module, the programmable control acquisition module and the high-voltage direct current power supply module;
the high-voltage direct-current power supply module converts the electric signal transmitted by the isolation and power supply module into a direct-current voltage signal with adjustable amplitude and transmits the direct-current voltage signal to the pulse forming module and the output switching module;
the computer control module generates pulse parameter adjustment data and transmits the pulse parameter adjustment data to the programmable control acquisition module;
the programmable control acquisition module generates a pulse control signal and an output switching signal;
the programmable control acquisition module transmits the pulse control signal to the pulse forming module and transmits the output switching signal to the output switching module;
the pulse forming module transmits pulse signals to the electrode through the output switching module;
the output switching module transmits pulse signals to part or all of the electrodes in the electrode group;
the electrodes receiving the pulse signals electrically stimulate the target area.
2. A pulsed electric field therapy apparatus according to claim 1, characterized in that: the system also comprises an external control module;
the external control function module comprises an external trigger function module and a foot switch;
the external triggering function module receives a synchronous control signal transmitted by external equipment and transmits the synchronous control signal to the programmable control acquisition module;
the foot switch generates a foot switch action signal and transmits the foot switch action signal to the programmable control acquisition module; the foot switch action signals comprise foot switch trigger action signals and foot switch release action signals;
the foot switch action signal is a foot switch trigger action signal, and the pulse forming module transmits a pulse signal to the electrode through the output switching module;
the foot switch action signal is a foot switch loosening action signal, and the pulse forming module only applies the pulse signal to the internal load Rint of the switching module, and does not transmit the pulse signal to the electrode.
3. A pulsed electric field therapy apparatus according to claim 1, characterized in that: the power filter is also included;
the power filter filters the electric signals output by the isolation and power supply module.
4. A pulsed electric field therapy apparatus according to claim 1, characterized in that: the pulse forming module outputs pulse signals with adjustable amplitude, pulse width, polarity and number.
5. A pulsed electric field therapy apparatus according to claim 1, characterized in that: the measuring circuit is also included;
the measuring circuit monitors real-time pulse parameters output by the pulse forming module and feeds the real-time pulse parameters back to the programmable control acquisition module.
6. A pulsed electric field therapy apparatus according to claim 1, characterized in that: the device also comprises a discharge circuit;
the discharging circuit is used for discharging the electric energy stored in the pulse forming module.
7. A pulsed electric field therapy apparatus according to claim 1, characterized in that: the device also comprises a foot switch circuit and an isolation device;
the foot switch circuit is used for receiving foot switch action signals generated by the foot switch and transmitting the foot switch action signals to the programmable control acquisition module through the isolation device.
8. A pulsed electric field therapy apparatus according to claim 1, characterized in that: the pulse forming module comprises a bipolar multi-level pulse generating circuit and a unipolar multi-level pulse generating circuit.
9. A pulsed electric field therapy apparatus according to claim 1, characterized in that: the emergency stop switch is also included;
the emergency stop switch is used for closing the pulse electric field treatment device.
10. A pulsed electric field therapy apparatus according to claim 1, characterized in that: a display for displaying the pulse operating state is also included.
CN202222254974.5U 2022-08-26 2022-08-26 Pulsed electric field therapeutic device Active CN219439389U (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202222254974.5U CN219439389U (en) 2022-08-26 2022-08-26 Pulsed electric field therapeutic device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202222254974.5U CN219439389U (en) 2022-08-26 2022-08-26 Pulsed electric field therapeutic device

Publications (1)

Publication Number Publication Date
CN219439389U true CN219439389U (en) 2023-08-01

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN202222254974.5U Active CN219439389U (en) 2022-08-26 2022-08-26 Pulsed electric field therapeutic device

Country Status (1)

Country Link
CN (1) CN219439389U (en)

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