CN114323899B

CN114323899B - Oscillation device for estrogen receptor modulator-treated osteoarticular inflammation detector and oscillation method thereof

Info

Publication number: CN114323899B
Application number: CN202210001404.7A
Authority: CN
Inventors: 段莉
Original assignee: Shenzhen Second Peoples Hospital
Current assignee: Shenzhen Second Peoples Hospital
Priority date: 2022-01-04
Filing date: 2022-01-04
Publication date: 2022-12-30
Anticipated expiration: 2042-01-04
Also published as: CN114323899A

Abstract

The invention relates to the technical field of reagent detection, in particular to a vibrating device for an estrogen receptor modulator treatment osteoarticular inflammation detector, which comprises a detection box, wherein a vibrating table is slidably connected in the middle of the lower end of the detection box, a connecting table is arrayed at the upper end of the vibrating table, a placing cavity is formed in the upper end surface of the connecting table, extruding plates are arranged on two sides of the placing cavity, the two extruding plates are symmetrically arranged by taking the placing cavity as a center, rubber bulges are arrayed on the inner walls of the two extruding plates, the placing cavity is of an arc-shaped structure, a connecting plate is fixedly connected in the middle of the detection box, a mounting cavity is arrayed in the middle of the connecting plate, a vibrating block is slidably connected in the mounting cavity, the vibrating block corresponds to the placing cavity one by one, a mounting through hole is formed in the middle of the vibrating block, detection test tubes are arranged in the middle of the mounting through hole, and the lower ends of the detection test tubes are located in the placing cavity.

Description

Oscillation device for estrogen receptor modulator-treated osteoarticular inflammation detector and oscillation method thereof

Technical Field

The invention relates to the technical field of reagent detection, in particular to a vibrating device for an estrogen receptor modulator-treated osteoarticular inflammation detector and a vibrating method thereof.

Background

Arthritis generally refers to inflammatory diseases caused by inflammation, infection, degeneration, trauma or other factors, and can be classified into bone, rheumatoid, ankylosis, reactivity, gout, rheumatism, suppuration, etc. according to the cause. According to statistics, half of people who are over 50 years old in China suffer from osteoarthritis, which is a very common disease in China. It has been found from the literature that estrogen can affect many organ systems. There are several ways in which estrogen acts on tissues, the most characteristic of which is its interaction with estrogen receptors, resulting in altered gene transcription. The use of estrogen receptors to treat osteoarthritis has begun in the clinic. When detecting the result, need add various reagents to shake it evenly, it is even that testing personnel shakes hand now mainly, shakes even effect relatively poorly, and the reagent in the test tube mixes inhomogeneously, influences the experimental result, and does not have among the current device and can make the test tube shake even and heat the many test tubes of hand shake even again automatically.

Disclosure of Invention

The invention aims to provide a vibrating device for an estrogen receptor modulator treatment osteoarticular inflammation detector and a vibrating method thereof. To solve the problems set forth in the background art described above.

In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides an estrogen receptor modulator treatment bone articular inflammation oscillation device for detector, includes the detection case, sliding connection has the vibration platform in the middle of the lower extreme of detection case, the upper end array of vibrating the platform has the connection platform, the up end of connecting the platform is equipped with places the chamber, the both sides of placing the chamber all are equipped with stripper plate, two the stripper plate is in order to place the chamber and set up as central symmetry, two it has rubber bulge all to array on the inner wall of stripper plate, it is the arc structure to place the chamber, the middle fixedly connected with connecting plate of detection case, the middle array of connecting plate has the installation cavity, sliding connection has the vibration piece in the installation cavity, vibrate the piece and place the chamber one-to-one, the centre of vibrating the piece is equipped with the installation through-hole, be equipped with the detection test tube in the middle of the installation through-hole, the lower extreme that detects the test tube is located places the intracavity, the both sides sliding connection of vibrating the piece has the drive plate, the lower extreme both sides of vibrating the piece all fixedly connected with fixed slat, the lower extreme and the connection platform fixed connection of fixed connection, two the fixed slat sets up as central symmetry with the installation through-hole, the side of fixed slat, the fixed side of fixed slat, the side of locking adjustment mechanism and the side of the stripper plate.

Preferably, the upper side of the fixed slat is of a V-shaped structure, the lower end of the fixed slat is of an L-shaped structure, and the corners of the V-shaped structure at the upper end of the fixed slat are vertical structures.

Preferably, locking adjustment mechanism is by mounting panel, lock plate, pressure regulating plate and reset spring, the intermediate position sliding connection of mounting panel and fixed slat, lock plate fixed connection is in the middle of the upper end of mounting panel, the lock plate is just to the vertical structure department of fixed slat, reset spring fixed connection is between lock plate and fixed slat, pressure regulating plate is located the upper end of mounting panel.

Preferably, the adjusting pressure plate is of a V-shaped structure, the corners of the adjusting pressure plate are hinged to the side ends of the fixed slats, the upper side of the adjusting pressure plate is of a horizontal structure, the lower side of the adjusting pressure plate is of an inclined structure, the top end of the lower side of the adjusting pressure plate is of a hook-shaped structure, and the top end of the lower side of the adjusting pressure plate abuts against the side end of the locking plate.

Preferably, the upper end of the drive plate is a pressing head, the lower end of the drive plate abuts against the upper side of the adjusting pressure plate, a fixing ring is fixedly connected between the two drive plates, and the axis of the fixing ring and the axis of the mounting through hole are on the same straight line.

Preferably, the middle array of shaking the platform has the connector, connect platform and connector one-to-one, connect in the middle of the left side of platform and connector rotation connection, fixedly connected with electric putter on the left side inner wall of detection case, shake the left side and the power take off end fixed connection of platform.

Preferably, the installation intracavity wall all is the arc structure with the lateral wall that vibrates the piece, be equipped with the spacing groove on the inside wall of installation chamber, vibrate the both sides of piece all fixedly connected with stopper, stopper sliding connection is in the spacing inslot.

Preferably, both sides of the lower end of the extrusion plate are fixedly connected with auxiliary plates, the upper end of the connecting table is provided with a sliding groove, and the auxiliary plates are slidably connected in the sliding groove.

A vibrating method of a vibrating device for an estrogen receptor modulator treatment osteoarticular inflammation detector comprises the following steps:

the method comprises the following steps: pressing the driving plate, driving the extrusion plate to move by the driving plate, placing the detection test tube added with the reagent in the installation through hole, and limiting and fixing the detection test tube by the extrusion plate;

step two: after the detection test tube is installed, the electric push rod drives the oscillating table to reciprocate back and forth, and when the oscillating table moves, the oscillating block is limited in the installation cavity, so that the connecting table rotates and inclines;

step three: the oscillating block is fixedly connected with the connecting table through the fixed strip plate, the oscillating block rotates along with the connecting table when the connecting table rotates, the connecting table and the oscillating block keep horizontal in the rotating process, and the reagents in the test tube are oscillated in reciprocating movement so that the reagents can be fully fused;

step four: vibrate the completion back, vibrate the platform and connect the platform and all keep the horizontality, conveniently take out the detection test tube.

Compared with the prior art, the invention has the beneficial effects that:

1. the connecting tables are arranged on the oscillating table, so that a plurality of test tubes are shaken up at one time, the test tubes with different diameters are clamped and fixed through the extrusion plate, the adaptability is stronger, and the test tubes are prevented from being collided and damaged in the shaking up process;

2. vibrate platform reciprocating motion back and forth through the drive of electric push rod, shake even processing to the test tube, guarantee the abundant mixture of reagent for testing result is more accurate.

Drawings

FIG. 1 is a schematic view of the connection structure inside the detection box;

FIG. 2 is a schematic view of a three-dimensional connection structure of the oscillating block and the connection table;

FIG. 3 is an enlarged view of point A;

FIG. 4 is a schematic view of a connection structure of the oscillating table.

In the figure: 1 detection case, 2 connecting plates, 21 installation cavity, 3 detection test tubes, 4 vibrate the piece, 5 installation through-holes, 6 spacing grooves, 7 spacing blocks, 8 connection platforms, 9 fixed slat, 10 drive plates, 101 solid fixed ring, 11 stripper plate, 12 rubber bulge, 13 accessory plate, 14 spouts, 15 place the chamber, 16 locking adjustment mechanism, 161 mounting panel, 162 locking plate, 163 pressure regulating plate, 164 reset spring, 17 vibrate platform, 18 connector.

Detailed Description

In order to further understand and appreciate the present invention, the technical solutions in the embodiments of the present invention will be clearly and completely described and illustrated in the drawings in the embodiments of the present invention, and it should be understood that the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments, and do not limit the embodiments in any way. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

Referring to fig. 1-4, the present invention provides a technical solution: the utility model provides an estrogen receptor modulator treatment bone joint's inflammation oscillation device for detector, including detection case 1, sliding connection vibrates platform 17 in the middle of the lower extreme of detection case 1, the upper end array that vibrates platform 17 has connection platform 8, the up end of connecting platform 8 is equipped with places chamber 15, the both sides of placing chamber 15 all are equipped with stripper plate 11, two stripper plate 11 are with placing chamber 15 and set up as central symmetry, all the array has rubber bulge 12 on the inner wall of two stripper plate 11, it is the arc structure to place chamber 15, the middle fixedly connected with connecting plate 2 of detection case 1, the middle array of connecting plate 2 has installation cavity 21, sliding connection has vibration piece 4 in installation cavity 21, vibrate piece 4 and place chamber 15 one-to-one, the centre of vibrating piece 4 is equipped with mounting hole 5, be equipped with detection test tube 3 in the middle of mounting hole 5, the lower extreme that detects test tube 3 is located places chamber 15, the both sides sliding connection of vibrating piece 4 has drive plate 10, the lower extreme both sides of vibrating piece 4 all fixedly connected with fixed slat 9, fixed slat 9's lower extreme and connection platform 8 fixed connection, two fixed slat 9 use mounting hole 5 to set up as central symmetry, the side end of

locking adjusting plate

16 and 16 connecting mechanism that the fixed connection that the side that the adjusting plate constructs.

The upside of fixed slat 9 is the V-arrangement structure, and the lower extreme of fixed slat 9 is the L shape structure, and the corner of fixed slat 9 upper end V-arrangement structure is vertical structure, connects platform 8 to carry out fixed connection through fixed slat 9 and shock piece 4, connects platform 8 to drive when rotatory to vibrate piece 4 and rotate together through fixed slat 9, guarantees that the two is in the horizontality, avoids colliding detection test tube 3.

Locking adjustment mechanism 16 is by mounting panel 161, lock plate 162, regulation pressure plate 163 and reset spring 164, the intermediate position sliding connection of mounting panel 161 and fixed slat 9, lock plate 162 fixed connection is in the middle of the upper end of mounting panel 161, lock plate 162 is just to the vertical structure department of fixed slat 9, reset spring 164 fixed connection is between lock plate 162 and fixed slat 9, regulation pressure plate 163 is located the upper end of mounting panel 161, mounting panel 161 can drive the removal of extrusion plate 11, it is fixed to press from both sides the clamp to detect test tube 3, adapt to the detection test tube 3 of different diameters.

The adjusting pressure plate 163 is of a V-shaped structure, the corners of the adjusting pressure plate 163 are hinged to the side ends of the fixing strips 9, the upper side of the adjusting pressure plate 163 is of a horizontal structure, the lower side of the adjusting pressure plate 163 is of an inclined structure, the top end of the lower side of the adjusting pressure plate 163 is of a hook-shaped structure, the top end of the lower side of the adjusting pressure plate 163 abuts against the side end of the locking plate 162, when the driving plate 10 is pressed, the upper end of the adjusting pressure plate 163 is pressed by the lower end of the driving plate 10, the adjusting pressure plate 163 rotates, the locking plate 162 is pressed by the lower end of the adjusting pressure plate 163, the mounting plate 161 and the pressing plate 11 are pushed to move, and the detection test tube 3 can be conveniently inserted.

The upper end of drive plate 10 is for pressing the head for press more comfortable, the lower extreme of drive plate 10 supports and leans on adjusting pressure plate 163 upside, the solid fixed ring 101 of fixedly connected with between two drive plates 10, gu fixed ring 101's axis and mounting hole 5's axis are on same straight line, gu fixed ring 101 can prescribe a limit to the position of drive plate 10, avoid drive plate 10 and shock piece 4 to drop when shaking even reagent.

Vibrate platform 17's middle array has connector 18, connect platform 8 and connector 18 one-to-one, rotate with connector 18 in the middle of connecting platform 8's the left side and connect, fixedly connected with electric push rod on the left side inner wall of detection case 1, vibrate platform 17's left side and power take off end fixed connection, electric push rod drives and vibrates platform 17 reciprocating motion that makes a round trip, vibrate platform 17 when the removal, it is restricted in installation cavity 21 to vibrate piece 4, make and connect platform 8 to take place the rotation slope.

The lateral wall of installation cavity 21 inner wall and shock piece 4 all is the arc structure, is equipped with spacing groove 6 on the inside wall of installation cavity 21, vibrates the both sides of piece 4 all fixedly connected with stopper 7, and stopper 7 sliding connection is in spacing groove 6, and spacing groove 6 restricts the displacement who vibrates piece 4 and stopper 7, carries out spacing fixed to vibrating piece 4 simultaneously, avoids shaking even in-process, vibrates piece 4 and takes place to drop.

All fixedly connected with accessory plate 13 in the lower extreme both sides of stripper plate 11, the upper end of connecting table 8 is equipped with spout 14, and accessory plate 13 sliding connection restricts the distance that stripper plate 11 removed in spout 14, and when avoiding not having centre gripping detection test tube 3, stripper plate 11 takes place to drop.

the method comprises the following steps: pressing the driving plate 10, driving the extrusion plate 11 to move by the driving plate 10, placing the detection test tube 3 added with the reagent in the installation through hole 5, and limiting and fixing the detection test tube by the extrusion plate 11;

step two: after the detection test tube 3 is installed, the electric push rod drives the oscillating table 17 to reciprocate back and forth, and when the oscillating table 17 moves, the oscillating block 4 is limited in the installation cavity 21, so that the connecting table 8 rotates and inclines;

step three: the oscillating block 4 is fixedly connected with the connecting table 8 through the fixed strip plate 9, the oscillating block 4 rotates along with the connecting table 8 when the connecting table 8 rotates, the connecting table 8 and the oscillating block 4 keep a horizontal state in the rotating process, and the reagents in the detection test tube 3 are oscillated in the reciprocating movement, so that the reagents can be fully fused;

step four: vibrate the completion back, vibrate platform 17 and connect platform 8 and all keep the horizontality, conveniently take out test tube 3.

While embodiments of the invention have been shown and described, it is emphasized that: the above description is presented for the purpose of illustration and description of an exemplary embodiment of the invention, and is not intended to limit the invention in any way. It will be appreciated by those skilled in the art that various changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides an estrogen receptor modulator treats vibration device for inflammation detector of bone joint, includes detection case (1), its characterized in that: the middle of the lower end of the detection box (1) is connected with a vibration table (17) in a sliding manner, the upper end array of the vibration table (17) is provided with a connection table (8), the upper end face of the connection table (8) is provided with a placing cavity (15), both sides of the placing cavity (15) are provided with extrusion plates (11), two extrusion plates (11) are arranged by taking the placing cavity (15) as central symmetry, two rubber bumps (12) are arranged on the inner wall of the extrusion plates (11) in an array manner, the placing cavity (15) is of an arc structure, the middle of the detection box (1) is fixedly connected with a connecting plate (2), the middle of the connecting plate (2) is provided with an installation cavity (21), the installation cavity (21) is internally provided with vibration blocks (4) in a sliding manner, the vibration blocks (4) correspond to the placing cavity (15) one by one, the middle of the vibration blocks (4) is provided with installation through holes (5), the middle of the installation through holes (5) is provided with detection plates (3), the lower end of the detection box (3) is positioned in the placing cavity (15), both sides of the test tube (9) are connected with fixed strips (9), and the test tube (9) are connected with two fixed strips (9) by the test tube fixed strips (9), the side of fixed slat (9) is equipped with locking adjustment mechanism (16), the top of locking adjustment mechanism (16) and the side fixed connection of stripper plate (11), the upside of fixed slat (9) is the V-arrangement structure, the lower extreme of fixed slat (9) is the L shape structure, the corner of fixed slat (9) upper end V-arrangement structure is vertical structure, locking adjustment mechanism (16) is by mounting panel (161), lock plate (162), regulation pressure plate (163) and reset spring (164), the intermediate position sliding connection of mounting panel (161) and fixed slat (9), lock plate (162) fixed connection is in the middle of the upper end of mounting panel (161), lock plate (162) just is fixed slat (9) vertical structure department, reset spring (164) fixed connection is between lock plate (162) and fixed slat (9), regulation pressure plate (163) are located the upper end of mounting panel (161), the upper end of drive plate (10) is the pressure head, the lower extreme of drive plate (10) supports and leans on and adjusts the upside of drive plate (163), two fixed slat (10) between the fixed slat (101), the straight line axis of connection piece (17) is connected with the straight line of the straight line (17) on the mounting plate (17), connect platform (8) and connector (18) one-to-one, rotate with connector (18) in the middle of the left side of connecting platform (8) and connect, fixedly connected with electric push rod on the left side inner wall of detection case (1), vibrate the left side and the power take off end fixed connection of platform (17), installation cavity (21) inner wall and the lateral wall that vibrates piece (4) all are the arc structure, be equipped with spacing groove (6) on the inside wall of installation cavity (21), the both sides of vibrating piece (4) all fixedly connected with stopper (7), stopper (7) sliding connection is in spacing groove (6), the lower extreme both sides of stripper plate (11) all fixedly connected with accessory plate (13), the upper end of connecting platform (8) is equipped with spout (14), accessory plate (13) sliding connection is in spout (14).

2. The oscillation device for the inflammation detector for the estrogen receptor modulator to treat the bone joint according to the claim 1, wherein: the adjusting pressure plate (163) is of a V-shaped structure, the corners of the adjusting pressure plate (163) are hinged to the side ends of the fixing strips (9), the upper side of the adjusting pressure plate (163) is of a horizontal structure, the lower side of the adjusting pressure plate (163) is of an inclined structure, the top end of the lower side of the adjusting pressure plate (163) is of a hook-shaped structure, and the top end of the lower side of the adjusting pressure plate (163) abuts against the side end of the locking plate (162).

3. A method for oscillating the oscillating device for the instrument for treating inflammation of bone joints with the estrogen receptor modulator according to any one of claims 1 to 2, wherein the method comprises the following steps:

the method comprises the following steps: pressing the driving plate (10), driving the extrusion plate (11) to move by the driving plate (10), placing the detection test tube (3) added with the reagent in the installation through hole (5), and limiting and fixing the detection test tube through the extrusion plate (11);

step two: after the detection test tube (3) is installed, the electric push rod drives the vibration table (17) to reciprocate back and forth, and when the vibration table (17) moves, the vibration block (4) is limited in the installation cavity (21), so that the connection table (8) rotates and inclines;

step three: the oscillating block (4) is fixedly connected with the connecting table (8) through the fixing strip plate (9), the oscillating block (4) rotates along with the connecting table (8) when the connecting table (8) rotates, the connecting table (8) and the oscillating block (4) keep a horizontal state in the rotating process, and reagents in the detection test tube (3) are oscillated in reciprocating movement so that the reagents can be fully fused;

step four: vibrate the completion back, vibrate platform (17) and connect platform (8) and all keep the horizontality, conveniently take out test tube (3).