CN1142934C - 作为药物的生物相容性载体的金属类可啉 - Google Patents

作为药物的生物相容性载体的金属类可啉 Download PDF

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Publication number
CN1142934C
CN1142934C CNB988138220A CN98813822A CN1142934C CN 1142934 C CN1142934 C CN 1142934C CN B988138220 A CNB988138220 A CN B988138220A CN 98813822 A CN98813822 A CN 98813822A CN 1142934 C CN1142934 C CN 1142934C
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CN
China
Prior art keywords
carbon atoms
metallocorrinoids
group
groups containing
nitric oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB988138220A
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English (en)
Chinese (zh)
Other versions
CN1284958A (zh
Inventor
Ja
J·A·保尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Akron
Original Assignee
University of Akron
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Akron filed Critical University of Akron
Publication of CN1284958A publication Critical patent/CN1284958A/zh
Application granted granted Critical
Publication of CN1142934C publication Critical patent/CN1142934C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CNB988138220A 1997-12-30 1998-12-30 作为药物的生物相容性载体的金属类可啉 Expired - Fee Related CN1142934C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/000581 1997-12-30
US09/000,581 US5936082A (en) 1997-12-30 1997-12-30 Metallocorrinoids as biologically compatible carriers of pharmacological agents

Publications (2)

Publication Number Publication Date
CN1284958A CN1284958A (zh) 2001-02-21
CN1142934C true CN1142934C (zh) 2004-03-24

Family

ID=21692125

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988138220A Expired - Fee Related CN1142934C (zh) 1997-12-30 1998-12-30 作为药物的生物相容性载体的金属类可啉

Country Status (11)

Country Link
US (1) US5936082A (enExample)
EP (1) EP1066292B1 (enExample)
JP (1) JP2001527077A (enExample)
CN (1) CN1142934C (enExample)
AU (1) AU754303B2 (enExample)
DE (1) DE69812721T2 (enExample)
DK (1) DK1066292T3 (enExample)
IN (1) IN192148B (enExample)
NO (1) NO316688B1 (enExample)
NZ (1) NZ505905A (enExample)
WO (1) WO1999033833A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739313A (en) 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
US6806363B1 (en) 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
AU4243400A (en) * 1999-10-15 2001-04-30 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging agents and as antitumor agents
AU785505B2 (en) 1999-10-15 2009-02-26 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
US7591995B2 (en) * 1999-10-15 2009-09-22 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
AU2002243438A1 (en) * 2000-10-25 2002-07-24 Mayo Foundation For Medical Education And Research Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
US6752986B2 (en) 2001-05-24 2004-06-22 The Cleveland Clinic Foundation Composition and methods for affecting metallocorrinoid uptake
EP1435973A4 (en) * 2001-09-28 2007-05-02 Mayo Foundation SIMULTANEOUS ADMINISTRATION OF A TRANSPORT PROTEIN WITH CONJUGATED COBALAMINE FOR THE DISTRIBUTION OF MEDICINAL PRODUCTS
EP1596815A4 (en) * 2003-02-20 2007-07-04 Cleveland Clinic Foundation COMPOSITION AND METHOD FOR INHIBITING THE SURVIVAL OF CELLS
US20070232996A1 (en) * 2004-04-29 2007-10-04 Cube Medical A/S Balloon for Use in Angioplasty with an Outer Layer of Nanofibers
WO2006020291A2 (en) * 2004-08-02 2006-02-23 Bebaas, Inc. Vitamin b12 compositions
BRPI0610419A2 (pt) * 2005-05-17 2012-10-23 Cargill Inc lecitina granular, lisolecitina, processo para produzir lecitina granular, composição granular, processo para produzir uma composição de lecitina granular, produto, e, processos para produzir lisolecitina granular e para produzir uma composição de lisolecitina granular
US20130131007A1 (en) 2005-09-07 2013-05-23 Bebaas, Inc. Vitamin b12 compositions
US20070178141A1 (en) * 2005-09-07 2007-08-02 Bebaas, Inc. Vitamin B12 compositions
WO2007087631A2 (en) * 2006-01-26 2007-08-02 Bebaas, Inc. Cobalamin compositions for the treatment of cancer
KR102241407B1 (ko) * 2019-08-22 2021-04-16 재단법인대구경북과학기술원 광분해성 코발트 나이트로실 착물 및 이를 포함하는 일산화질소 전달체

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0210014A (ja) * 1988-06-28 1990-01-12 Matsushita Seiko Co Ltd ごみ処理装置
WO1990010014A1 (fr) * 1989-02-28 1990-09-07 Teijin Limited Nouveau derive de vitamine b12, sa production et son application
WO1995031204A1 (en) * 1994-05-17 1995-11-23 Research Corporation Technologies, Inc. Cobalamins as nitric oxide sequestrants

Also Published As

Publication number Publication date
EP1066292B1 (en) 2003-03-26
IN192148B (enExample) 2004-02-28
US5936082A (en) 1999-08-10
NZ505905A (en) 2003-05-30
AU754303B2 (en) 2002-11-14
CN1284958A (zh) 2001-02-21
DE69812721T2 (de) 2004-01-15
JP2001527077A (ja) 2001-12-25
DE69812721D1 (de) 2003-04-30
AU2023399A (en) 1999-07-19
NO20003411L (no) 2000-08-14
DK1066292T3 (da) 2003-07-14
HK1034257A1 (en) 2001-10-19
NO316688B1 (no) 2004-04-05
NO20003411D0 (no) 2000-06-29
EP1066292A4 (en) 2001-08-16
WO1999033833A1 (en) 1999-07-08
EP1066292A1 (en) 2001-01-10

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