CN114272517A - Transcranial magnetic pulse waveform conversion circuit - Google Patents
Transcranial magnetic pulse waveform conversion circuit Download PDFInfo
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- CN114272517A CN114272517A CN202111584966.0A CN202111584966A CN114272517A CN 114272517 A CN114272517 A CN 114272517A CN 202111584966 A CN202111584966 A CN 202111584966A CN 114272517 A CN114272517 A CN 114272517A
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Abstract
The invention discloses a transcranial magnetic pulse waveform conversion circuit, which comprises an input port, an output port and a control signal port, wherein the input port and the control signal port are used as the input of a drive control circuit, the output of the drive control circuit is connected to a direction conversion circuit, and the input of the direction conversion circuit is connected to the output of the drive control circuit; the direction conversion circuit is of an H-bridge structure consisting of Q1, Q2, Q3, Q4, Q5, Q6, Q7 and Q8 silicon controlled rectifiers, is connected with a half sine wave shaping circuit, and is also connected with a single-phase wave shaping circuit.
Description
Technical Field
The invention relates to the field of transcranial magnetic pulse waveform control circuits, in particular to a transcranial magnetic pulse waveform conversion circuit.
Background
Transcranial Magnetic Stimulation (TMS) is a non-invasive technique acting on cerebral cortex, and is a physical nerve regulation technique which mainly utilizes the principle that a time-varying magnetic field generates induction current to apply a pulse magnetic field on the cerebral cortex so as to depolarize cortical neurons to generate action potential and influence the electrical activity of the cerebral cortex. Through more than thirty years of research and clinical application, transcranial magnetic stimulation has been proved to have wide application prospects in treatment of diseases such as Parkinson's disease, epilepsy and relevant dyskinesia, depression and mood disorder, cerebral apoplexy, schizophrenia, chronic pain and the like. In addition, the transcranial magnetic stimulation can be used for objective and direct motor nervous system or sensory nervous system function examination, and can be used for diagnosing and evaluating nervous system diseases such as conductivity of corticospinal tracts, excitability of motor cortex, function of central nervous system damage, prognosis evaluation and the like. Recent studies have shown that transcranial magnetic stimulation also has application in new fields, such as improving human memory, and treating tobacco, alcohol and drug addiction.
Since the first modern transcranial magnetic stimulation instrument was developed by Barker et al in 1985, the transcranial magnetic stimulation technology developed various output modes such as single-pulse transcranial magnetic stimulation, repeated transcranial magnetic stimulation, burst type transcranial magnetic stimulation, double-pulse paired transcranial magnetic stimulation, and the like. In the aspect of marketization of transcranial magnetic stimulation instruments, various transcranial magnetic stimulation instruments with mature technologies and excellent designs are introduced at home and abroad, but from the aspect of pulse waveform types, the currently marketed transcranial magnetic stimulation instruments are generally single-cycle sine waves, and no other types of waveforms appear.
The basic principle of the conventional transcranial magnetic stimulation instrument is shown in fig. 1, and the conventional transcranial magnetic stimulation instrument consists of a charging circuit, an energy storage capacitor, a silicon controlled switch and a stimulation coil, wherein the silicon controlled switch is turned on when pulses are output, a discharge loop is formed by the energy storage capacitor and the stimulation coil, current flows through the coil, and the current is electromagnetically converted to output biphase sine wave magnetic field pulses.
Disclosure of Invention
The invention provides a transcranial magnetic pulse waveform conversion circuit, and aims to solve the problem that the existing transcranial magnetic pulse stimulation equipment can only output a single-cycle sine wave.
According to the embodiment of the application, a transcranial magnetic pulse waveform conversion circuit is provided, which comprises an input port, an output port and a control signal port, wherein the input port and the control signal port are used as the input of a driving control circuit, the output of the driving control circuit is connected to a direction conversion circuit, the input of the direction conversion circuit is connected to the output of the driving control circuit, and the output of the direction conversion circuit is used as the output port; the direction conversion circuit is an H-bridge structure consisting of eight thyristors of Q1, Q2, Q3, Q4, Q5, Q6, Q7 and Q8; the direction conversion circuit is also connected with a half sine wave shaping circuit, and the half sine wave shaping circuit consists of a controlled silicon Q9 and an L-Load; the direction conversion circuit is also connected with a single-phase wave shaping circuit, and the single-phase wave shaping circuit is composed of a controllable silicon Q10 and an R-Load.
Preferably, the driving control circuit is used for analyzing the control signal and identifying the trigger signal.
Preferably, the driving control circuit is composed of a logic gate circuit and a QD flip-flop.
Compared with the prior art, the transcranial magnetic pulse waveform conversion circuit provided by the invention has the following beneficial effects:
by adopting the H-bridge structure of a plurality of silicon controlled rectifiers, the types of output magnetic stimulation pulse waveforms are increased, the waveform direction can be changed, different types of nerve depolarization can be caused, and different nerve regulation and control functions are expanded. Meanwhile, as the interface of the conversion circuit is simple and the connection is clear, the conversion circuit can be used as an expansion part of the existing transcranial magnetic stimulation system under the condition of not influencing the existing magnetic stimulation system, and can also be assembled in the form of modules in the transcranial magnetic stimulation system at the beginning of design to achieve the capability of multi-waveform output, thereby being convenient for the improvement of the existing equipment by users.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
Fig. 1 is a circuit diagram of the basic principle of a prior art transcranial magnetic stimulation apparatus.
Fig. 2 is a block diagram of a transcranial magnetic pulse waveform conversion circuit according to a first embodiment of the present invention.
Fig. 3 is a circuit diagram of a transcranial magnetic pulse waveform conversion circuit according to a first embodiment of the invention.
Fig. 4 is a circuit diagram of the output positive or negative going waveform of a transcranial magnetic pulse waveform conversion circuit according to a first embodiment of the invention.
Fig. 5 is a circuit diagram of a sinusoidal waveform output by a transcranial magnetic pulse waveform conversion circuit according to a first embodiment of the present invention.
Fig. 6 is a circuit diagram of a half sine wave output by a transcranial magnetic pulse waveform conversion circuit according to a first embodiment of the present invention.
Fig. 7 is a circuit diagram of a single-phase waveform output by a transcranial magnetic pulse waveform conversion circuit according to a first embodiment of the invention.
Description of reference numerals:
11. an input port; 12. an output port; 13. a control signal port; 14. a direction conversion circuit; 15. a half sine waveform shaping circuit; 16. single-phase wave shaping circuit.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It is also to be understood that the terminology used in the description of the invention herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used in the specification of the present invention and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
It should be further understood that the term "and/or" as used in this specification and the appended claims refers to and includes any and all possible combinations of one or more of the associated listed items.
Referring to fig. 2 and 3, the present invention discloses a transcranial magnetic pulse waveform conversion circuit, which is used to be connected between a transcranial magnetic stimulation generating device and a stimulation coil. The transcranial magnetic pulse waveform conversion circuit comprises an input port 11, an output port 12 and a control signal port 13, wherein the input port 11 and the control signal port 13 are used as the input of a driving control circuit, the output of the driving control circuit is connected to a direction conversion circuit 14, the input of the direction conversion circuit 14 is connected to the output of the driving control circuit, and the output of the direction conversion circuit 14 is used as the output port 12.
Specifically, the direction conversion circuit 14 is of an H-bridge structure consisting of eight thyristors, namely Q1, Q2, Q3, Q4, Q5, Q6, Q7 and Q8, the direction conversion circuit is further connected with a half-sine wave shaping circuit 15, the half-sine wave shaping circuit 15 consists of the thyristors, namely Q9 and L-Load, the direction conversion circuit 14 is further connected with a single-phase wave shaping circuit 16, and the single-phase wave shaping circuit 16 consists of the thyristors, namely Q10 and R-Load.
It can be understood that the input port 11 is connected to the conventional transcranial magnetic stimulation generating device, the output port 12 is connected to the connection interface of the transcranial magnetic stimulation coil, the control signal port 13 is used for setting the circuit working mode and receiving the magnetic field output pulse control signal, the half sine wave shaping circuit 15 can convert the output waveform into a half sine wave when working, and the single-phase wave shaping circuit 16 can convert the output waveform into a single-phase wave when working.
It can be understood that, in fig. 3, the Mode3 is the control signal port 13, the Mode control signal connected to the input terminal of the drive control circuit includes a Mode [0], a Mode [1] and a Mode [2] total three-way interface, Trigger is the input port 11, and timer + and timer-are the output ports 12
In this embodiment, the driving control circuit is composed of a logic gate circuit and a QD flip-flop, and is used for analyzing the control signal and identifying the trigger signal. Specifically, as shown in fig. 4, the direction change principle of the circuit of the present invention is shown in fig. 4, when the highest Mode [2] of the control signal Mode is 0, the driving control circuit only sets Q1, Q2, Q7 and Q8 to operate, and current only flows through the path when the magnetic pulse trigger is generated, and the output direction is the forward direction (as shown by the forward arrow in fig. 5). On the contrary, when the Mode [2] is 1, the drive control circuit only sets the Q3, the Q4, the Q5 and the Q6 to work, the current flows through the path when the magnetic pulse trigger is generated, the flowing direction of the stimulating coil is reversed, and the output direction is negative (a negative arrow in fig. 5).
Referring to FIG. 5, when the control signal Mode [1:0] is 00, Q9 and Q10 are completely turned off, except for direction adjustment, the stimulating coil is connected directly to the magnetic pulse generating circuit, and the waveform of the magnetic field output is sine wave.
Referring to fig. 6, fig. 6 shows the half sine wave output principle of the circuit of the present invention, when the control signal Mode [1:0] is 01, the waveform shaping circuit Q10 is completely turned off, when the magnetic pulse trigger is generated, the trigger control circuit opens the H-bridge according to the setting direction until the sine wave positive half cycle output is completed, and the Q9 waveform shaping circuit is turned on in the negative half cycle to return the voltage energy to the magnetic pulse generating circuit through the L-Load, at this time, the magnetic field generated on the stimulating coil is a half sine magnetic field wave.
Referring to fig. 7, fig. 7 shows the principle of single-phase wave output of the circuit of the present invention, when the control signal Mode [1:0] is 10, the waveform shaping circuit Q9 is completely turned off, when the magnetic pulse trigger is generated, the trigger control circuit opens the H-bridge according to the setting direction until the magnetic field sine wave reaches the maximum value, then the IGBT Q10 waveform shaping circuit is turned on to consume the current energy through the resistor R-Load until the waveform output is completed, and at this time, the magnetic field generated on the stimulation coil is a single-phase magnetic field wave.
Compared with the prior art, the transcranial magnetic pulse waveform conversion circuit provided by the invention has the following beneficial effects:
by adopting the H-bridge structure of a plurality of silicon controlled rectifiers, the types of output magnetic stimulation pulse waveforms are increased, the waveform direction can be changed, different types of nerve depolarization can be caused, and different nerve regulation and control functions are expanded. Meanwhile, as the interface of the conversion circuit is simple and the connection is clear, the conversion circuit can be used as an expansion part of the existing transcranial magnetic stimulation system under the condition of not influencing the existing magnetic stimulation system, and can also be assembled in the form of modules in the transcranial magnetic stimulation system at the beginning of design to achieve the capability of multi-waveform output, thereby being convenient for the improvement of the existing equipment by users.
While the invention has been described with reference to specific embodiments, the invention is not limited thereto, and various equivalent modifications and substitutions can be easily made by those skilled in the art within the technical scope of the invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (3)
1. A transcranial magnetic pulse waveform conversion circuit is characterized by comprising an input port, an output port and a control signal port, wherein the input port and the control signal port are used as the input of a drive control circuit, the output of the drive control circuit is connected with a direction conversion circuit, the input of the direction conversion circuit is connected with the output of the drive control circuit, and the output of the direction conversion circuit is used as the output port;
the direction conversion circuit is an H-bridge structure consisting of eight thyristors of Q1, Q2, Q3, Q4, Q5, Q6, Q7 and Q8;
the direction conversion circuit is also connected with a half sine wave shaping circuit, and the half sine wave shaping circuit consists of a controlled silicon Q9 and an L-Load;
the direction conversion circuit is also connected with a single-phase wave shaping circuit, and the single-phase wave shaping circuit is composed of a controllable silicon Q10 and an R-Load.
2. The transcranial magnetic pulse waveform conversion circuit according to claim 1, wherein: the drive control circuit is used for analyzing the control signal and identifying the trigger signal.
3. The transcranial magnetic pulse waveform conversion circuit according to claim 1, wherein: the driving control circuit consists of a logic gate circuit and a QD trigger.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111584966.0A CN114272517A (en) | 2021-12-22 | 2021-12-22 | Transcranial magnetic pulse waveform conversion circuit |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111584966.0A CN114272517A (en) | 2021-12-22 | 2021-12-22 | Transcranial magnetic pulse waveform conversion circuit |
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| Publication Number | Publication Date |
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| CN114272517A true CN114272517A (en) | 2022-04-05 |
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| CN202111584966.0A Pending CN114272517A (en) | 2021-12-22 | 2021-12-22 | Transcranial magnetic pulse waveform conversion circuit |
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