CN114271540A - 过滤嘴、卷烟及雾化组件 - Google Patents
过滤嘴、卷烟及雾化组件 Download PDFInfo
- Publication number
- CN114271540A CN114271540A CN202210047940.0A CN202210047940A CN114271540A CN 114271540 A CN114271540 A CN 114271540A CN 202210047940 A CN202210047940 A CN 202210047940A CN 114271540 A CN114271540 A CN 114271540A
- Authority
- CN
- China
- Prior art keywords
- hyaluronic acid
- filter
- powder
- filter according
- filter tip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 235000019504 cigarettes Nutrition 0.000 title claims abstract description 11
- 238000000889 atomisation Methods 0.000 title abstract description 15
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 96
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 96
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 96
- 239000003595 mist Substances 0.000 claims abstract description 23
- 239000000126 substance Substances 0.000 claims abstract description 23
- 239000000843 powder Substances 0.000 claims description 38
- 239000000463 material Substances 0.000 claims description 23
- 239000011324 bead Substances 0.000 claims description 17
- 239000000654 additive Substances 0.000 claims description 9
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 8
- 230000000996 additive effect Effects 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 7
- 239000011162 core material Substances 0.000 claims description 6
- 150000002711 medium chain fatty acid esters Chemical class 0.000 claims description 6
- 239000011812 mixed powder Substances 0.000 claims description 6
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 5
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims description 5
- 229940041616 menthol Drugs 0.000 claims description 5
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 claims description 4
- PVXPPJIGRGXGCY-TZLCEDOOSA-N 6-O-alpha-D-glucopyranosyl-D-fructofuranose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)C(O)(CO)O1 PVXPPJIGRGXGCY-TZLCEDOOSA-N 0.000 claims description 4
- 235000019359 magnesium stearate Nutrition 0.000 claims description 4
- 235000010413 sodium alginate Nutrition 0.000 claims description 4
- 239000000661 sodium alginate Substances 0.000 claims description 4
- 229940005550 sodium alginate Drugs 0.000 claims description 4
- 229920001817 Agar Polymers 0.000 claims description 3
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 3
- 108010010803 Gelatin Proteins 0.000 claims description 3
- 150000007649 L alpha amino acids Chemical class 0.000 claims description 3
- 229930195725 Mannitol Natural products 0.000 claims description 3
- 239000004373 Pullulan Substances 0.000 claims description 3
- 229920001218 Pullulan Polymers 0.000 claims description 3
- 239000008272 agar Substances 0.000 claims description 3
- 235000010419 agar Nutrition 0.000 claims description 3
- 235000013869 carnauba wax Nutrition 0.000 claims description 3
- 239000004203 carnauba wax Substances 0.000 claims description 3
- 235000010418 carrageenan Nutrition 0.000 claims description 3
- 239000000679 carrageenan Substances 0.000 claims description 3
- 229920001525 carrageenan Polymers 0.000 claims description 3
- 229940113118 carrageenan Drugs 0.000 claims description 3
- 239000008273 gelatin Substances 0.000 claims description 3
- 229920000159 gelatin Polymers 0.000 claims description 3
- 235000019322 gelatine Nutrition 0.000 claims description 3
- 235000011852 gelatine desserts Nutrition 0.000 claims description 3
- 239000000594 mannitol Substances 0.000 claims description 3
- 235000010355 mannitol Nutrition 0.000 claims description 3
- 235000019423 pullulan Nutrition 0.000 claims description 3
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 3
- 235000010643 Leucaena leucocephala Nutrition 0.000 claims description 2
- 240000007472 Leucaena leucocephala Species 0.000 claims description 2
- 230000009286 beneficial effect Effects 0.000 abstract description 11
- 238000010521 absorption reaction Methods 0.000 abstract description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 16
- 239000000741 silica gel Substances 0.000 description 12
- 229910002027 silica gel Inorganic materials 0.000 description 12
- 239000000835 fiber Substances 0.000 description 8
- 241000208125 Nicotiana Species 0.000 description 6
- 235000002637 Nicotiana tabacum Nutrition 0.000 description 6
- 238000004804 winding Methods 0.000 description 6
- 239000007788 liquid Substances 0.000 description 4
- 230000000391 smoking effect Effects 0.000 description 4
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- 238000005422 blasting Methods 0.000 description 3
- 239000003571 electronic cigarette Substances 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 210000002345 respiratory system Anatomy 0.000 description 3
- 230000037303 wrinkles Effects 0.000 description 3
- 229920000954 Polyglycolide Polymers 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 229920001577 copolymer Polymers 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 125000005456 glyceride group Chemical group 0.000 description 2
- 239000008176 lyophilized powder Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000000178 monomer Substances 0.000 description 2
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical group CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 2
- 229920000747 poly(lactic acid) Polymers 0.000 description 2
- 239000004633 polyglycolic acid Substances 0.000 description 2
- 239000004626 polylactic acid Substances 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- -1 polypropylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000377 silicon dioxide Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 244000215068 Acacia senegal Species 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 229920000084 Gum arabic Polymers 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 description 1
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 description 1
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 description 1
- 235000010489 acacia gum Nutrition 0.000 description 1
- 239000000205 acacia gum Substances 0.000 description 1
- AEMOLEFTQBMNLQ-WAXACMCWSA-N alpha-D-glucuronic acid Chemical compound O[C@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O AEMOLEFTQBMNLQ-WAXACMCWSA-N 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000003796 beauty Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 150000002016 disaccharides Chemical class 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000001125 extrusion Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 210000001156 gastric mucosa Anatomy 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000008407 joint function Effects 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 229950006780 n-acetylglucosamine Drugs 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/18—Treatment of tobacco products or tobacco substitutes
- A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
- A24B15/281—Treatment of tobacco products or tobacco substitutes by chemical substances the action of the chemical substances being delayed
- A24B15/283—Treatment of tobacco products or tobacco substitutes by chemical substances the action of the chemical substances being delayed by encapsulation of the chemical substances
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D1/00—Cigars; Cigarettes
- A24D1/04—Cigars; Cigarettes with mouthpieces or filter-tips
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D1/00—Cigars; Cigarettes
- A24D1/04—Cigars; Cigarettes with mouthpieces or filter-tips
- A24D1/045—Cigars; Cigarettes with mouthpieces or filter-tips with smoke filter means
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/02—Manufacture of tobacco smoke filters
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/02—Manufacture of tobacco smoke filters
- A24D3/0204—Preliminary operations before the filter rod forming process, e.g. crimping, blooming
- A24D3/0212—Applying additives to filter materials
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/02—Manufacture of tobacco smoke filters
- A24D3/0204—Preliminary operations before the filter rod forming process, e.g. crimping, blooming
- A24D3/0212—Applying additives to filter materials
- A24D3/0216—Applying additives to filter materials the additive being in the form of capsules, beads or the like
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/04—Tobacco smoke filters characterised by their shape or structure
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/04—Tobacco smoke filters characterised by their shape or structure
- A24D3/048—Tobacco smoke filters characterised by their shape or structure containing additives
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
- A24D3/061—Use of materials for tobacco smoke filters containing additives entrapped within capsules, sponge-like material or the like, for further release upon smoking
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
- A24D3/08—Use of materials for tobacco smoke filters of organic materials as carrier or major constituent
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
- A24D3/14—Use of materials for tobacco smoke filters of organic materials as additive
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/06—Use of materials for tobacco smoke filters
- A24D3/16—Use of materials for tobacco smoke filters of inorganic materials
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
- A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
- A24D3/17—Filters specially adapted for simulated smoking devices
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
- C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cigarettes, Filters, And Manufacturing Of Filters (AREA)
- Cosmetics (AREA)
Abstract
本发明公开一种过滤嘴、应用该过滤嘴的卷烟及应用该过滤嘴的雾化组件。其中，过滤嘴包括滤嘴本体和含透明质酸的物质，所述含透明质酸的物质负载于所述滤嘴本体。本发明的技术方案能够使经过过滤嘴的雾气可以负载对人体有益的物质，以实现人体更好地吸收。
Description
技术领域
本发明涉及雾化吸收技术领域，特别涉及一种过滤嘴、应用该过滤嘴的卷烟及应用该过滤嘴的雾化组件。
背景技术
由雾化器产生的雾气将对人体有益的物质输送进入肺部是吸收效果较佳的输送方式。如何使雾化器的雾气能够负载对人体有益的物质，目前尚未发现较好的方式，如能突破将会有很大市场前景，惠及人体健康。
发明内容
本发明的主要目的是提供一种过滤嘴、应用该过滤嘴的卷烟及应用该过滤嘴的雾化组件，旨在使经过过滤嘴的雾气可以负载对人体有益的物质，以实现人体更好地吸收。
为实现上述目的，本发明提出的过滤嘴包括滤嘴本体和含透明质酸的物质，所述含透明质酸的物质负载于所述滤嘴本体。
在本发明一实施例中，所述含透明质酸的物质为含透明质酸的粉末或含透明质酸的爆珠。
在本发明一实施例中，所述含透明质酸的粉末为透明质酸粉末或透明质酸粉末与添加剂的混合粉末。
在本发明一实施例中，所述添加剂包括薄荷醇、硬脂酸镁、巴西蜡、甘露糖醇、L-α-氨基酸、异麦芽酮糖中的至少一种。
在本发明一实施例中，所述含透明质酸的爆珠包括壁材和被所述壁材包覆的芯材，所述芯材由透明质酸粉末混悬于中链脂肪酸酯中制得。
在本发明一实施例中，所述壁材包括明胶、海藻酸钠、普鲁兰多糖、阿拉伯胶、卡拉胶、琼脂中的至少一种。
在本发明一实施例中，所述透明质酸粉末的粒度分布为0.001μm～0.1mm。
在本发明一实施例中，所述透明质酸的相对分子量分布在103～108。
为实现上述目的，本发明提出的卷烟包括过滤嘴，所述过滤嘴包括滤嘴本体和含透明质酸的物质，所述含透明质酸的物质负载于所述滤嘴本体。
为实现上述目的，本发明提出的雾化组件包括雾化器和过滤嘴，所述过滤嘴包括滤嘴本体和含透明质酸的物质，所述含透明质酸的物质负载于所述滤嘴本体，所述过滤嘴安装在所述雾化器的雾气出口处，以使所述雾化器产生的雾气经所述过滤嘴而导出。
本发明的技术方案，将含透明质酸的物质负载于滤嘴本体，以制得过滤嘴。当这样的过滤嘴与例如雾化器的可以产生雾气的主体配合时，随着雾气的不断产生，雾气将流经过滤嘴而其中的含透明质酸的物质接触，从而负载上透明质酸而进入人体，进而实现人体对透明质酸的吸收。即，本发明的技术方案，能够使经过过滤嘴的雾气可以负载对人体有益的物质，以实现人体更好地吸收。
具体实施方式
下面将对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明的一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有作出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
另外，各个实施例之间的技术方案可以相互结合，但是必须是以本领域普通技术人员能够实现为基础，当技术方案的结合出现相互矛盾或无法实现时应当认为这种技术方案的结合不存在，也不在本发明要求的保护范围之内。
针对背景技术所反映的问题，本发明提出一种过滤嘴，该过滤嘴包括滤嘴本体和含透明质酸的物质，所述含透明质酸的物质负载于所述滤嘴本体。
需要说明的是，透明质酸(英文全称hyaluronic acid，英文简称HA)，又称玻尿酸，分子式为(C14H21NO11)n，是D-葡萄糖醛酸和N-乙酰葡糖胺组成的双糖单位糖胺聚糖。
透明质酸作为生化药物，广泛应用于各类眼科手术，以及用于治疗关节炎和加速伤口愈合。当其用于化妆品中时，则能起到独特的保护皮肤作用，可保持皮肤滋润光滑、细腻柔嫩、富有弹性，具有防皱、抗皱、美容保健及恢复皮肤生理功能的作用。
同时，透明质酸还可以作为食品，其经口服消化吸收后，人体内透明质酸合成的前体增加，从而可使人体内透明质酸含量提高并集中定位于皮肤组织，进而增强皮肤的保水能力，软化皮肤角质层，起到改善肌肤弹性和减少皱纹的功效。与含透明质酸的化妆品仅作用于皮肤表层起局部性保湿作用不同，口服透明质酸通过外源性透明质酸降解、吸收及体内再合成，增加了内源性透明质酸含量，从而具有整体美容保健的功效。此外，透明质酸还能促进肠道抵抗部分种类的细菌感染，改善关节功能，以及起到保护胃黏膜的作用。
因此，本发明的技术方案，将含透明质酸的物质负载于滤嘴本体，以制得过滤嘴。当这样的过滤嘴与例如雾化器的可以产生雾气的主体配合时，随着雾气的不断产生，雾气将流经过滤嘴而其中的含透明质酸的物质接触，从而负载上透明质酸而进入人体，进而实现人体对透明质酸的吸收。即，本发明的技术方案，能够使经过过滤嘴的雾气可以负载对人体有益的物质，以实现人体更好地吸收。
可以理解地，前述与过滤嘴进行配合的雾化器，既可以是医用雾化设备中的雾化器，也可以是电子烟中的雾化器，还可以是其他形式的雾化器。
关于前述过滤嘴，本发明进一步提出两种具体的实现形式：
(1)过滤嘴中含透明质酸的物质为含透明质酸的粉末；
可以理解地，含透明质酸的粉末，既可以是透明质酸粉末，也可以是透明质酸粉末与添加剂粉末的混合粉末；即，将透明质酸以粉末形式制成纯品粉末或者混合粉末，再安置进入滤嘴本体中。
具体地，将透明质酸以粉末形式制成纯品粉末时，可以采用透明质酸的冻干粉。并且，还可以进一步利用低温粉碎技术对该纯品粉末进行粉碎处理，且将粒度控制在0.001μm～0.1mm之间；其中，粒度可以是0.001μm、0.002μm、0.005μm、0.01μm、0.02μm、0.05μm、0.1μm、0.2μm、0.5μm、1μm、2μm、5μm、10μm、50μm、100μm。
将透明质酸以粉末形式制成混合粉末时，同样可以采用透明质酸的冻干粉；此时，冻干的透明质酸粉末需要与一种或多种具有自润滑性、低吸湿性的食品级添加剂粉末进行混合；其中，添加剂可以是薄荷醇、硬脂酸镁、巴西蜡、甘露糖醇、L-α-氨基酸、异麦芽酮糖等。并且，还可以进一步利用低温粉碎技术对该混合粉末进行粉碎处理，且将粒度控制在0.001μm～0.1mm之间；其中，粒度可以是0.001μm、0.002μm、0.005μm、0.01μm、0.02μm、0.05μm、0.1μm、0.2μm、0.5μm、1μm、2μm、5μm、10μm、50μm、100μm。
此外，还需要说明的是，将含透明质酸的粉末充填至滤嘴本体中时，滤嘴本体主要由卷筒、滤材、多孔硅胶塞构成。在一种可选的实施例中，卷筒为两端开口的筒状结构，卷筒具有背对设置的烟油端和吸食端；滤材和多孔硅胶塞均填充在卷筒中，滤材和多孔硅胶塞沿烟油端至吸食端的方向依次设置，多孔硅胶塞内部形成有气道，气道沿烟油端至吸食端的方向贯穿多孔硅胶塞的两端；滤材和硅胶塞之间形成中空腔，含透明质酸的粉末填充于该中空腔内。如此的结构设置，在用户抽吸时，雾气先经过滤材过滤、降温后进入中空腔内，中空腔内含透明质酸的粉末散发并随雾气流经多孔硅胶塞的气道，最后流出并进入人体的口腔内，而被人体吸收。其中，滤材包括聚乳酸纤维，或者聚羟基乙酸纤维，或者聚丙烯纤维，或者前述聚合物单体中的至少两种的共聚物纤维。
(2)过滤嘴中含透明质酸的物质为含透明质酸的爆珠；
即，将透明质酸制作成爆珠，再以爆珠的形式充填至滤嘴本体中。这样，使用时通过挤压，使爆珠破裂，使其中含有透明质酸的液体流出随雾气进入人体口腔，即可被人体有效吸收。
具体地，含透明质酸的爆珠包括壁材和被壁材包覆的芯材；其中，芯材由透明质酸粉末混悬于中链脂肪酸酯中制得；壁材包括明胶、海藻酸钠、普鲁兰多糖、阿拉伯胶、卡拉胶、琼脂中的至少一种。其中，透明质酸粉末可以采用透明质酸的冻干粉，中链脂肪酸酯可以采用辛癸酸甘油酯；并且，含透明质酸的爆珠的直径可以控制在2mm～5mm之间。
当然，可以理解地，在将透明质酸粉末混悬于中链脂肪酸酯中时，中链脂肪酸酯中还可以按照实际应用场景的需求，添加其他添加剂，添加剂的形式可以是粉末，也可以是液体。
此外，还需要说明的是，类似将含透明质酸的粉末充填至滤嘴本体中，将为含透明质酸的爆珠填充至滤嘴本体中时，滤嘴本体也主要由卷筒、滤材、多孔硅胶塞构成。在一种可选的实施例中，卷筒为两端开口的筒状结构，卷筒具有背对设置的烟油端和吸食端；滤材和多孔硅胶塞均填充在卷筒中，滤材和多孔硅胶塞沿烟油端至吸食端的方向依次设置，多孔硅胶塞内部形成有气道，气道沿烟油端至吸食端的方向贯穿多孔硅胶塞的两端；滤材和硅胶塞之间形成中空腔，含透明质酸的爆珠填充于该中空腔内。如此的结构设置，在用户抽吸时，雾气先经过滤材过滤、降温后进入中空腔内，中空腔内含透明质酸的爆珠受挤压破裂会有含有透明质酸的液体流出而散发并随雾气流经多孔硅胶塞的气道，最后流出并进入人体的口腔内，而被人体吸收。其中，滤材包括聚乳酸纤维，或者聚羟基乙酸纤维，或者聚丙烯纤维，或者前述聚合物单体中的至少两种的共聚物纤维。
另外，需要说明的是，不论是含透明质酸的粉末，还是含透明质酸的爆珠，其中的透明质酸都是以分子的形式存在的。此时，本实施例将透明质酸的相对分子量选定在103～108的范围内。具体地，透明质酸的相对分子量可以是103、104、105、106、107、108。可以理解地，透明质酸的来源包括动物提取和微生物发酵。
下面通过具体实施例对本发明过滤嘴进行详细说明：
实施例1：载透明质酸冻干粉的过滤嘴的制备
冻干透明质酸粉末70g，加入10g薄荷醇，10g异麦芽酮糖，硬脂酸镁1g，混合后通过低温粉碎机粉碎至15μm以内，分装到1000支滤嘴本体中，以制得过滤嘴。微细颗粒化的透明质酸更容易进入呼吸道，越细小颗粒越能获得长程的自由飞行距离，从而深入呼吸道内部，在组织的外壁获得分布，从而滋养呼吸道上皮组织。
实施例2：载透明质酸爆珠的过滤嘴的制备
20mL辛癸酸甘油酯，加入1g薄荷醇，2mL甘油，溶解混匀后，加入冻干透明质酸粉末18g，形成混悬液，通过海藻酸钠包封形成爆珠1000粒，并分装到1000支滤嘴本体中，以制得过滤嘴。通过辛癸酸甘油酯分散的透明质酸包封在爆珠之中，可以抑制高度亲水的透明质酸粘聚，保持其生物活性，在消化道内分散更加均匀容易以较大分子量状态下直接吸收，更有益健康。
综上，本发明的含透明质酸的过滤嘴可广泛应用于雾化组件(例如医用雾化设备、电子烟等)、卷烟中，可使经过过滤嘴的雾气可以负载对人体有益的物质，以实现人体更好地吸收。
本发明还提出了一种卷烟，该卷烟包括如前所述的过滤嘴，该过滤嘴的具体实施方式可参照前述过滤嘴部分的相关内容。由于本卷烟采用了前述所有实施例的全部技术方案，因此至少具有前述所有实施例的全部技术方案所带来的所有有益效果，在此不再一一赘述。
本发明还提出了一种雾化组件，该雾化组件包括雾化器和如前所述的过滤嘴，该过滤嘴的具体实施方式可参照前述过滤嘴部分的相关内容。由于本雾化组件采用了前述所有实施例的全部技术方案，因此至少具有前述所有实施例的全部技术方案所带来的所有有益效果，在此不再一一赘述。
其中，所述过滤嘴安装在所述雾化器的雾气出口处，以使所述雾化器产生的雾气经所述过滤嘴而导出。
可以理解地，雾化组件既可以是医用雾化设备中的雾化组件，也可以是电子烟中的雾化组件；当然，还可以是其他设备中的雾化组件。
以上所述仅为本发明的优选实施例，并非因此限制本发明的专利范围，凡是在本发明的发明构思下，利用本发明说明书内容所作的等效结构变换，或直接/间接运用在其他相关的技术领域均包括在本发明的专利保护范围内。
Claims (10)
1.一种过滤嘴，其特征在于，包括滤嘴本体和含透明质酸的物质，所述含透明质酸的物质负载于所述滤嘴本体。
2.如权利要求1所述的过滤嘴，其特征在于，所述含透明质酸的物质为含透明质酸的粉末或含透明质酸的爆珠。
3.如权利要求2所述的过滤嘴，其特征在于，所述含透明质酸的粉末为透明质酸粉末或透明质酸粉末与添加剂的混合粉末。
4.如权利要求3所述的过滤嘴，其特征在于，所述添加剂包括薄荷醇、硬脂酸镁、巴西蜡、甘露糖醇、L-α-氨基酸、异麦芽酮糖中的至少一种。
5.如权利要求2所述的过滤嘴，其特征在于，所述含透明质酸的爆珠包括壁材和被所述壁材包覆的芯材，所述芯材由透明质酸粉末混悬于中链脂肪酸酯中制得。
6.如权利要求5所述的过滤嘴，其特征在于，所述壁材包括明胶、海藻酸钠、普鲁兰多糖、阿拉伯胶、卡拉胶、琼脂中的至少一种。
7.如权利要求3至6中任一项所述的过滤嘴，其特征在于，所述透明质酸粉末的粒度分布为0.001μm～0.1mm。
8.如权利要求1至6中任一项所述的过滤嘴，其特征在于，所述透明质酸的相对分子量分布在103～108。
9.一种卷烟，其特征在于，包括如权利要求1至8中任一项所述的过滤嘴。
10.一种雾化组件，其特征在于，包括雾化器和如权利要求1至9中任一项所述的过滤嘴，所述过滤嘴安装在所述雾化器的雾气出口处，以使所述雾化器产生的雾气经所述过滤嘴而导出。
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210047940.0A CN114271540A (zh) | 2022-01-17 | 2022-01-17 | 过滤嘴、卷烟及雾化组件 |
| PCT/CN2022/072919 WO2023133915A1 (zh) | 2022-01-17 | 2022-01-20 | 过滤嘴、卷烟及雾化组件 |
| KR1020227012568A KR20230111584A (ko) | 2022-01-17 | 2022-01-20 | 필터, 궐련 및 분무화 어셈블리 |
| JP2022524072A JP2024519191A (ja) | 2022-01-17 | 2022-01-20 | フィルタ、巻きたばこ及び霧化組立体 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210047940.0A CN114271540A (zh) | 2022-01-17 | 2022-01-17 | 过滤嘴、卷烟及雾化组件 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN114271540A true CN114271540A (zh) | 2022-04-05 |
Family
ID=80881022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210047940.0A Pending CN114271540A (zh) | 2022-01-17 | 2022-01-17 | 过滤嘴、卷烟及雾化组件 |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JP2024519191A (zh) |
| KR (1) | KR20230111584A (zh) |
| CN (1) | CN114271540A (zh) |
| WO (1) | WO2023133915A1 (zh) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5758669A (en) * | 1995-10-05 | 1998-06-02 | Daicel Chemical Industries, Limited | Tobacco filters and production process thereof |
| CN101731757A (zh) * | 2009-12-08 | 2010-06-16 | 湖南中烟工业有限责任公司 | 保湿剂在卷烟纸质滤材中的应用 |
| CN103113686A (zh) * | 2013-01-30 | 2013-05-22 | 福建中烟工业有限责任公司 | 降低烟气中重金属释放量的保润树脂的制备方法及应用 |
| CN104886554A (zh) * | 2015-04-30 | 2015-09-09 | 山东圣健生物科技有限公司 | 爆珠软胶囊及其制备方法 |
| CN106690412A (zh) * | 2017-03-06 | 2017-05-24 | 云南芯韵科技开发有限公司 | 一种含纸质线的功能化滤棒及其制备方法 |
| CN112931940A (zh) * | 2021-03-19 | 2021-06-11 | 深圳市智叶科技有限公司 | 过滤嘴和电子烟 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060090769A1 (en) * | 2004-11-02 | 2006-05-04 | Philip Morris Usa Inc. | Temperature sensitive powder for enhanced flavor delivery in smoking articles |
| CN105601983B (zh) * | 2016-03-10 | 2020-09-15 | 云南中烟工业有限责任公司 | 一种天然多糖气凝胶、其制备方法及在卷烟中的应用 |
| CN112220102B (zh) * | 2020-09-25 | 2022-12-09 | 山东华熙海御生物医药有限公司 | 一种含透明质酸和依克多因的电子烟液及其制备方法 |
| CN214509367U (zh) * | 2021-01-29 | 2021-10-29 | 高国庆 | 一种新型电子烟 |
| CN214759094U (zh) * | 2021-03-19 | 2021-11-19 | 深圳市智叶科技有限公司 | 过滤嘴以及电子烟 |
| CN113812672B (zh) * | 2021-09-24 | 2022-08-02 | 任国涛 | 一种含透明质酸钠的电子烟烟油及其制备方法 |
-
2022
- 2022-01-17 CN CN202210047940.0A patent/CN114271540A/zh active Pending
- 2022-01-20 KR KR1020227012568A patent/KR20230111584A/ko unknown
- 2022-01-20 WO PCT/CN2022/072919 patent/WO2023133915A1/zh active Application Filing
- 2022-01-20 JP JP2022524072A patent/JP2024519191A/ja active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5758669A (en) * | 1995-10-05 | 1998-06-02 | Daicel Chemical Industries, Limited | Tobacco filters and production process thereof |
| CN101731757A (zh) * | 2009-12-08 | 2010-06-16 | 湖南中烟工业有限责任公司 | 保湿剂在卷烟纸质滤材中的应用 |
| CN103113686A (zh) * | 2013-01-30 | 2013-05-22 | 福建中烟工业有限责任公司 | 降低烟气中重金属释放量的保润树脂的制备方法及应用 |
| CN104886554A (zh) * | 2015-04-30 | 2015-09-09 | 山东圣健生物科技有限公司 | 爆珠软胶囊及其制备方法 |
| CN106690412A (zh) * | 2017-03-06 | 2017-05-24 | 云南芯韵科技开发有限公司 | 一种含纸质线的功能化滤棒及其制备方法 |
| CN112931940A (zh) * | 2021-03-19 | 2021-06-11 | 深圳市智叶科技有限公司 | 过滤嘴和电子烟 |
Non-Patent Citations (1)
| Title |
|---|
| 单熙滨: "《制药工程》", 北京医科大学，中国协和医科大学联合出版社, pages: 405 - 406 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2023133915A1 (zh) | 2023-07-20 |
| JP2024519191A (ja) | 2024-05-09 |
| KR20230111584A (ko) | 2023-07-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4766745B2 (ja) | 経鼻式吸入器 | |
| KR100598138B1 (ko) | 니코틴 흡입기 | |
| Taylor et al. | Ultrasonic nebulisers for pulmonary drug delivery | |
| AU685458B2 (en) | Nasal drug delivery composition containing nicotine | |
| Douafer et al. | Scope and limitations on aerosol drug delivery for the treatment of infectious respiratory diseases | |
| Möbus et al. | Zinc–alginate microparticles for controlled pulmonary delivery of proteins prepared by spray-drying | |
| Goel et al. | Exploring targeted pulmonary delivery for treatment of lung cancer | |
| US5607662A (en) | Pharmaceutical inhalation compositions | |
| JP2002543165A (ja) | エーロゾル化および吸入のための組成物 | |
| JP2023086774A (ja) | 乾燥粉末配合および使用方法 | |
| US20120042886A1 (en) | Method of producing a nicotine medicament and a medicament made by the method | |
| JPH072654A (ja) | 吸入によるタウリン投与装置 | |
| JPH01221313A (ja) | 昇華放出薬剤組成物とその放出システム | |
| CN114271540A (zh) | 过滤嘴、卷烟及雾化组件 | |
| JP5981123B2 (ja) | ニコチン薬の製造法およびその方法により製造される医薬 | |
| Aragao-Santiago et al. | Innovative formulations for controlled drug delivery to the lungs and the technical and toxicological challenges to overcome | |
| Cassano et al. | Hydrogel based on hyaluronic acid | |
| Sheth et al. | Polymers for pulmonary drug delivery | |
| Lin et al. | Novel microencapsulated Pluronic–chitosan nanomicelles for lung delivery | |
| CA2265198C (en) | Method of producing a nicotine medicament and a medicament made by the method | |
| JP4097737B2 (ja) | 鼻口腔用抗炎症散布剤 | |
| CA2480123C (en) | Highly aqueous liquid carrier formulations | |
| CN214547161U (zh) | 嘴棒以及雾化吸食装置 | |
| CN217743138U (zh) | 嘴棒以及雾化吸食装置 | |
| KR20050105490A (ko) | 경폐 투여용 서방성 제제학적 조성물 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20220405 |