CN114258281A - 荧光成像系统 - Google Patents

荧光成像系统 Download PDF

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Publication number
CN114258281A
CN114258281A CN202080057859.XA CN202080057859A CN114258281A CN 114258281 A CN114258281 A CN 114258281A CN 202080057859 A CN202080057859 A CN 202080057859A CN 114258281 A CN114258281 A CN 114258281A
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CN
China
Prior art keywords
target tissue
excitation light
light
video image
camera
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Pending
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CN202080057859.XA
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English (en)
Chinese (zh)
Inventor
R·冢岛
M·A·阿莫尔索罗
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Rebound Therapeutics Corp
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Rebound Therapeutics Corp
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Publication of CN114258281A publication Critical patent/CN114258281A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A61B17/3423—Access ports, e.g. toroid shape introducers for instruments or hands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/0036—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room including treatment, e.g., using an implantable medical device, ablating, ventilating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077—Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/6865—Access ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
    • A61B5/7425—Displaying combinations of multiple images regardless of image source, e.g. displaying a reference anatomical image with a live image
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0036—Porphyrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3417—Details of tips or shafts, e.g. grooves, expandable, bendable; Multiple coaxial sliding cannulas, e.g. for dilating
    • A61B17/3421—Cannulas
    • A61B17/3423—Access ports, e.g. toroid shape introducers for instruments or hands
    • A61B2017/3425—Access ports, e.g. toroid shape introducers for instruments or hands for internal organs, e.g. heart ports
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B2090/103—Cranial plugs for access to brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/373—Surgical systems with images on a monitor during operation using light, e.g. by using optical scanners

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Neurology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endoscopes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN202080057859.XA 2019-08-23 2020-08-21 荧光成像系统 Pending CN114258281A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/550,159 2019-08-23
US16/550,159 US20210052161A1 (en) 2019-08-23 2019-08-23 Fluorescence imaging system
PCT/US2020/047415 WO2021041217A1 (en) 2019-08-23 2020-08-21 Fluorescence imaging system

Publications (1)

Publication Number Publication Date
CN114258281A true CN114258281A (zh) 2022-03-29

Family

ID=74646583

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080057859.XA Pending CN114258281A (zh) 2019-08-23 2020-08-21 荧光成像系统

Country Status (8)

Country Link
US (1) US20210052161A1 (https=)
EP (1) EP4017399A4 (https=)
JP (1) JP2022545172A (https=)
KR (1) KR20220054326A (https=)
CN (1) CN114258281A (https=)
AU (2) AU2020336268A1 (https=)
CA (1) CA3149612A1 (https=)
WO (1) WO2021041217A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116942055A (zh) * 2023-06-19 2023-10-27 武汉迈瑞医疗技术研究院有限公司 一种内窥镜图像处理装置、系统、方法及存储介质

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US12557989B2 (en) 2021-03-12 2026-02-24 Stryker European Operations Limited Neurosurgical methods and systems for detecting and removing tumorous tissue
JP7702294B2 (ja) 2021-07-27 2025-07-03 富士フイルム株式会社 内視鏡システム及びその作動方法
WO2023102718A1 (zh) * 2021-12-07 2023-06-15 中国科学院深圳先进技术研究院 基于荧光显微镜的自由活动的脊髓成像方法、装置及应用
CN114569874A (zh) * 2022-05-09 2022-06-03 精微致远医疗科技(武汉)有限公司 一种应用于可视化导丝的成像控制器主机及图像处理方法

Citations (5)

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US20050288556A1 (en) * 2004-06-29 2005-12-29 Pentax Corporation Electronic endoscope system for fluorescence observation
CN102370462A (zh) * 2010-07-13 2012-03-14 索尼公司 成像装置、成像系统、手术导航系统和成像方法
US20140171764A1 (en) * 2012-12-13 2014-06-19 General Electric Company Systems and methods for nerve imaging
US20180153408A1 (en) * 2016-05-10 2018-06-07 Ze Shan YAO Multispectral synchronized imaging
CN109843200A (zh) * 2016-08-17 2019-06-04 瑞邦治疗股份有限公司 具有近端安装的摄像机的套管

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CA2042075C (en) * 1991-05-08 2001-01-23 Branko Palcic Endoscopic imaging system
AU2003272531A1 (en) * 2003-09-15 2005-04-27 Beth Israel Deaconess Medical Center Medical imaging systems
JP5160276B2 (ja) * 2008-03-24 2013-03-13 富士フイルム株式会社 画像表示方法及び装置
EP2384686B8 (en) * 2009-04-21 2013-01-16 Olympus Medical Systems Corp. Fluorescence image device and fluorescence image acquiring method
US8706184B2 (en) * 2009-10-07 2014-04-22 Intuitive Surgical Operations, Inc. Methods and apparatus for displaying enhanced imaging data on a clinical image
US9134243B2 (en) * 2009-12-18 2015-09-15 University Health Network System and method for sub-surface fluorescence imaging
EP2359745A1 (en) * 2010-02-12 2011-08-24 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Method and device for multi-spectral photonic imaging
KR102416278B1 (ko) * 2013-04-23 2022-07-05 세다르스-신나이 메디칼 센터 형광단들로부터의 가시 광 이미지 및 적외선 광 이미지를 동시에 레코딩하기 위한 시스템들 및 방법들
CN106572792B (zh) * 2014-06-05 2020-03-06 海德堡大学 用于多光谱成像的方法和部件
WO2016126879A1 (en) * 2015-02-03 2016-08-11 The Arizona Board Of Regents On Behalf Of The University Of Arizona Falloposcope and method for ovarian cancer detection
KR101784063B1 (ko) * 2015-08-03 2017-10-11 국립암센터 펜타입의 의료용 형광 이미지 장치 및 이를 이용한 다중 형광 영상의 정합 시스템
JP7110174B2 (ja) * 2016-08-17 2022-08-01 リバウンド セラピュティクス コーポレーション 近位に取り付けられたカメラを備えるカニューレ
JP6512320B2 (ja) * 2018-02-21 2019-05-15 株式会社島津製作所 イメージング装置

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Publication number Priority date Publication date Assignee Title
US20050288556A1 (en) * 2004-06-29 2005-12-29 Pentax Corporation Electronic endoscope system for fluorescence observation
CN102370462A (zh) * 2010-07-13 2012-03-14 索尼公司 成像装置、成像系统、手术导航系统和成像方法
US20140171764A1 (en) * 2012-12-13 2014-06-19 General Electric Company Systems and methods for nerve imaging
US20180153408A1 (en) * 2016-05-10 2018-06-07 Ze Shan YAO Multispectral synchronized imaging
CN109843200A (zh) * 2016-08-17 2019-06-04 瑞邦治疗股份有限公司 具有近端安装的摄像机的套管

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116942055A (zh) * 2023-06-19 2023-10-27 武汉迈瑞医疗技术研究院有限公司 一种内窥镜图像处理装置、系统、方法及存储介质

Also Published As

Publication number Publication date
KR20220054326A (ko) 2022-05-02
AU2023233093A1 (en) 2023-10-05
AU2020336268A1 (en) 2022-02-24
JP2022545172A (ja) 2022-10-26
CA3149612A1 (en) 2021-03-04
EP4017399A4 (en) 2023-08-30
EP4017399A1 (en) 2022-06-29
WO2021041217A1 (en) 2021-03-04
US20210052161A1 (en) 2021-02-25

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