CN114207436A - 基于c-c基序趋化因子配体14测量而评估和治疗肾损伤的方法 - Google Patents

基于c-c基序趋化因子配体14测量而评估和治疗肾损伤的方法 Download PDF

Info

Publication number
CN114207436A
CN114207436A CN202080052788.4A CN202080052788A CN114207436A CN 114207436 A CN114207436 A CN 114207436A CN 202080052788 A CN202080052788 A CN 202080052788A CN 114207436 A CN114207436 A CN 114207436A
Authority
CN
China
Prior art keywords
subject
renal
acute
creatinine
cystatin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202080052788.4A
Other languages
English (en)
Chinese (zh)
Inventor
J·P·康甫
T·科万
P·麦克菲森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smart Medicine Co ltd
Original Assignee
Smart Medicine Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smart Medicine Co ltd filed Critical Smart Medicine Co ltd
Publication of CN114207436A publication Critical patent/CN114207436A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN202080052788.4A 2019-05-24 2020-05-22 基于c-c基序趋化因子配体14测量而评估和治疗肾损伤的方法 Pending CN114207436A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962852961P 2019-05-24 2019-05-24
US62/852,961 2019-05-24
PCT/US2020/034400 WO2020243011A1 (en) 2019-05-24 2020-05-22 Methods for evaluation and treatment of renal injury based on c-c motif chemokine ligand 14 measurement

Publications (1)

Publication Number Publication Date
CN114207436A true CN114207436A (zh) 2022-03-18

Family

ID=73554165

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202080052788.4A Pending CN114207436A (zh) 2019-05-24 2020-05-22 基于c-c基序趋化因子配体14测量而评估和治疗肾损伤的方法

Country Status (7)

Country Link
US (1) US20220236285A1 (https=)
EP (1) EP3977118A4 (https=)
JP (1) JP2022532947A (https=)
CN (1) CN114207436A (https=)
AU (1) AU2020282321A1 (https=)
CA (1) CA3141817A1 (https=)
WO (1) WO2020243011A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021381364A1 (en) * 2020-11-18 2023-06-22 Astute Medical, Inc. Methods and compositions for treatment of renal injury and renal failure
US20220284243A1 (en) * 2021-03-03 2022-09-08 International Business Machines Corporation Ensemble voting classifiers using adjusted thresholds
WO2023168299A1 (en) * 2022-03-03 2023-09-07 Astute Medical, Inc. Methods and compositions for assessing and treating persistent acute kidney injury based on c-c motif chemokine ligand 14 measurement
JP2025141825A (ja) * 2024-03-15 2025-09-29 台北医学大学 急性腎臓病予測方法及び予測システム

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107003301A (zh) * 2014-10-20 2017-08-01 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
WO2018132702A1 (en) * 2017-01-12 2018-07-19 Astute Medical, Inc. Methods and compositions for evaluation and treatment of renal injury and renal failure based on c-c motif chemokine ligand 14 measurement

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105556305A (zh) * 2013-06-05 2016-05-04 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断及预后的方法和组合物
US11327082B2 (en) * 2017-09-13 2022-05-10 B.R.A.H.M.S Gmbh Proadrenomedullin as a marker for abnormal platelet levels

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107003301A (zh) * 2014-10-20 2017-08-01 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
WO2018132702A1 (en) * 2017-01-12 2018-07-19 Astute Medical, Inc. Methods and compositions for evaluation and treatment of renal injury and renal failure based on c-c motif chemokine ligand 14 measurement

Also Published As

Publication number Publication date
EP3977118A4 (en) 2023-06-14
CA3141817A1 (en) 2020-12-03
EP3977118A1 (en) 2022-04-06
AU2020282321A1 (en) 2021-12-23
WO2020243011A1 (en) 2020-12-03
US20220236285A1 (en) 2022-07-28
JP2022532947A (ja) 2022-07-20

Similar Documents

Publication Publication Date Title
EP3734280B1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP7217796B2 (ja) 腎障害および腎不全の診断および予後のための方法および組成物
DK2666872T3 (en) Methods and compositions for the diagnosis and prognosis of renal injury and renal insufficiency
WO2010059996A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2010054389A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
WO2010091236A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and failure
HK1200218A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1220764A1 (zh) 肾损伤和肾衰竭的诊断及预後
CN114207436A (zh) 基于c-c基序趋化因子配体14测量而评估和治疗肾损伤的方法
CN107003325A (zh) 用于诊断和预后肾损伤和肾衰竭的方法和组合物
JP6538353B2 (ja) 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
EP3233106B1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1207155A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1236621A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1236620A1 (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP2018518676A (ja) 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
CN107735147A (zh) 用于肾损伤和肾衰竭的诊断和预后的方法和组合物
HK1167455B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1219129A1 (zh) 用於肾损伤和肾衰竭的诊断及预後的方法和组合物
HK1203620B (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
HK1168129B (en) Diagnosis and prognosis of renal injury and renal failure
HK1162617B (zh) 腎損傷和腎衰竭的診斷和預後
HK1195128A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination