CA3141817A1 - Methods for evaluation and treatment of renal injury based on c-c motif chemokine ligand 14 measurement - Google Patents

Methods for evaluation and treatment of renal injury based on c-c motif chemokine ligand 14 measurement Download PDF

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Publication number
CA3141817A1
CA3141817A1 CA3141817A CA3141817A CA3141817A1 CA 3141817 A1 CA3141817 A1 CA 3141817A1 CA 3141817 A CA3141817 A CA 3141817A CA 3141817 A CA3141817 A CA 3141817A CA 3141817 A1 CA3141817 A1 CA 3141817A1
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CA
Canada
Prior art keywords
subject
renal
acute
creatinine
ccl14
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3141817A
Other languages
English (en)
French (fr)
Inventor
James Patrick Kampf
Thomas Kwan
Paul Mcpherson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astute Medical Inc
Original Assignee
Astute Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astute Medical Inc filed Critical Astute Medical Inc
Publication of CA3141817A1 publication Critical patent/CA3141817A1/en
Pending legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/521—Chemokines
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA3141817A 2019-05-24 2020-05-22 Methods for evaluation and treatment of renal injury based on c-c motif chemokine ligand 14 measurement Pending CA3141817A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962852961P 2019-05-24 2019-05-24
US62/852,961 2019-05-24
PCT/US2020/034400 WO2020243011A1 (en) 2019-05-24 2020-05-22 Methods for evaluation and treatment of renal injury based on c-c motif chemokine ligand 14 measurement

Publications (1)

Publication Number Publication Date
CA3141817A1 true CA3141817A1 (en) 2020-12-03

Family

ID=73554165

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3141817A Pending CA3141817A1 (en) 2019-05-24 2020-05-22 Methods for evaluation and treatment of renal injury based on c-c motif chemokine ligand 14 measurement

Country Status (7)

Country Link
US (1) US20220236285A1 (https=)
EP (1) EP3977118A4 (https=)
JP (1) JP2022532947A (https=)
CN (1) CN114207436A (https=)
AU (1) AU2020282321A1 (https=)
CA (1) CA3141817A1 (https=)
WO (1) WO2020243011A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2021381364A1 (en) * 2020-11-18 2023-06-22 Astute Medical, Inc. Methods and compositions for treatment of renal injury and renal failure
US20220284243A1 (en) * 2021-03-03 2022-09-08 International Business Machines Corporation Ensemble voting classifiers using adjusted thresholds
WO2023168299A1 (en) * 2022-03-03 2023-09-07 Astute Medical, Inc. Methods and compositions for assessing and treating persistent acute kidney injury based on c-c motif chemokine ligand 14 measurement
JP2025141825A (ja) * 2024-03-15 2025-09-29 台北医学大学 急性腎臓病予測方法及び予測システム

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105556305A (zh) * 2013-06-05 2016-05-04 阿斯图特医药公司 用于肾损伤和肾衰竭的诊断及预后的方法和组合物
CN107003301B (zh) * 2014-10-20 2019-11-01 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
JP2020504157A (ja) * 2017-01-12 2020-02-06 アスチュート メディカル，インコーポレイテッド Ｃ−ｃモチーフケモカインリガンド１４の測定に基づく腎損傷および腎不全の評価および処置のための方法および組成物
US11327082B2 (en) * 2017-09-13 2022-05-10 B.R.A.H.M.S Gmbh Proadrenomedullin as a marker for abnormal platelet levels

Also Published As

Publication number Publication date
CN114207436A (zh) 2022-03-18
EP3977118A4 (en) 2023-06-14
EP3977118A1 (en) 2022-04-06
AU2020282321A1 (en) 2021-12-23
WO2020243011A1 (en) 2020-12-03
US20220236285A1 (en) 2022-07-28
JP2022532947A (ja) 2022-07-20

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Effective date: 20260105