CN114207151A - 治疗泌尿系统癌症的方法 - Google Patents

治疗泌尿系统癌症的方法 Download PDF

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Publication number
CN114207151A
CN114207151A CN202080053765.5A CN202080053765A CN114207151A CN 114207151 A CN114207151 A CN 114207151A CN 202080053765 A CN202080053765 A CN 202080053765A CN 114207151 A CN114207151 A CN 114207151A
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patient
pharmaceutically acceptable
acceptable salt
fgfr3
infigratinib
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R·帕尼库奇
S·阿兰吉奥
C·伯曼
M·蒙泰思
H·索伊弗
G·李
C·丹布科夫斯基
D·穆尔里尼
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Qed Pharmaceutical Co ltd
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Qed Pharmaceutical Co ltd
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61M2210/00—Anatomical parts of the body
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CN202080053765.5A 2019-05-31 2020-05-29 治疗泌尿系统癌症的方法 Pending CN114207151A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962855277P 2019-05-31 2019-05-31
US62/855,277 2019-05-31
US201962906194P 2019-09-26 2019-09-26
US62/906,194 2019-09-26
PCT/US2020/035140 WO2020243442A1 (en) 2019-05-31 2020-05-29 Methods of treating urinary system cancers

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CN114207151A true CN114207151A (zh) 2022-03-18

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EP (1) EP3976833A4 (enExample)
JP (1) JP2022534118A (enExample)
KR (1) KR20220088830A (enExample)
CN (1) CN114207151A (enExample)
AU (1) AU2020282816A1 (enExample)
CA (1) CA3141871A1 (enExample)
IL (1) IL288408A (enExample)
MX (1) MX2021014524A (enExample)
PH (1) PH12021552973A1 (enExample)
SG (1) SG11202112932QA (enExample)
WO (1) WO2020243442A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115785001A (zh) * 2022-11-23 2023-03-14 斯坦德药典标准物质研发(湖北)有限公司 一种英菲格拉替尼的制备方法
WO2024093681A1 (zh) * 2022-11-01 2024-05-10 Qed医药股份有限公司 英菲格拉替尼在治疗胃癌和腺癌中的用途

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KR20230121825A (ko) * 2020-12-18 2023-08-21 큐이디 테라퓨틱스, 인크. 연골무형성증을 치료하는 방법
CN117558346B (zh) * 2023-09-01 2024-12-03 上海仁东医学检验所有限公司 Utuc分子分型及预后预测模型构建方法

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CN107002141A (zh) * 2014-09-26 2017-08-01 詹森药业有限公司 使用fgfr突变基因组鉴定将对用fgfr抑制剂进行治疗有反应的癌症患者
TW201839399A (zh) * 2017-02-06 2018-11-01 比利時商健生藥品公司 癌症治療

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CN110785184A (zh) * 2017-02-06 2020-02-11 雷尼尔医疗公司 用于治疗癌症的方法，组合物和试剂盒
BR112020002555A2 (pt) * 2017-08-07 2020-08-11 The Johns Hopkins University métodos e materiais para avaliar e tratar câncer

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CN103757026A (zh) * 2013-12-20 2014-04-30 广州圣露生物技术有限公司 FGFR2b胞外段的基因序列、多肽及其应用
CN107002141A (zh) * 2014-09-26 2017-08-01 詹森药业有限公司 使用fgfr突变基因组鉴定将对用fgfr抑制剂进行治疗有反应的癌症患者
TW201839399A (zh) * 2017-02-06 2018-11-01 比利時商健生藥品公司 癌症治療

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"BGJ398 in Non-Muscle-Invasive Urothelial Carcinoma of the Bladder", pages 6, Retrieved from the Internet <URL:https://clinicaltrials.gov/ct2/show/record/NCT02657486? term=infigratinib&cond=bladder+cancer&draw=2&rank=3&view=record> *
NAZLI DIZMAN 等: "Infigratinib in upper tract urothelial carcinoma vs urothelial carcinoma of the bladder and association with comprehensive genomic profiling /cell-free DNA results", JOURNAL OF CLINICAL ONCOLOGY, vol. 37, no. 15, 26 May 2019 (2019-05-26), pages 1 *
SUMANTA K. PAL 等: "Efficacy of BGJ398, a Fibroblast Growth Factor Receptor 1–3 Inhibitor, in Patients with Previously Treated Advanced Urothelial Carcinoma with FGFR3 Alterations", 《CANCER DISCOV》, vol. 8, no. 7, pages 813 *
邓通 等: "2018年EAU非肌层浸润性膀胱癌指南解读――诊断、复发与进展风险评估篇", 《中国研究型医院》, no. 5 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024093681A1 (zh) * 2022-11-01 2024-05-10 Qed医药股份有限公司 英菲格拉替尼在治疗胃癌和腺癌中的用途
CN115785001A (zh) * 2022-11-23 2023-03-14 斯坦德药典标准物质研发(湖北)有限公司 一种英菲格拉替尼的制备方法
CN115785001B (zh) * 2022-11-23 2023-09-15 斯坦德药典标准物质研发(湖北)有限公司 一种英菲格拉替尼的制备方法

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IL288408A (en) 2022-01-01
KR20220088830A (ko) 2022-06-28
AU2020282816A1 (en) 2022-01-06
EP3976833A4 (en) 2023-07-05
MX2021014524A (es) 2022-05-19
SG11202112932QA (en) 2021-12-30
JP2022534118A (ja) 2022-07-27
US20220233537A1 (en) 2022-07-28
CA3141871A1 (en) 2020-12-03
PH12021552973A1 (en) 2022-07-11
EP3976833A1 (en) 2022-04-06

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