CN114206936B - 用于治疗癌症的组合物和方法 - Google Patents

用于治疗癌症的组合物和方法 Download PDF

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CN114206936B
CN114206936B CN202080052834.0A CN202080052834A CN114206936B CN 114206936 B CN114206936 B CN 114206936B CN 202080052834 A CN202080052834 A CN 202080052834A CN 114206936 B CN114206936 B CN 114206936B
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cells
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CN114206936A (zh
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凯文·弗里德曼
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Regeneron Pharmaceuticals Inc
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2 Savinti Biology
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A61K40/31—Chimeric antigen receptors [CAR]
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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CN202080052834.0A 2019-06-14 2020-06-11 用于治疗癌症的组合物和方法 Active CN114206936B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962861838P 2019-06-14 2019-06-14
US62/861,838 2019-06-14
US202062991314P 2020-03-18 2020-03-18
US62/991,314 2020-03-18
PCT/US2020/037145 WO2020252110A1 (en) 2019-06-14 2020-06-11 Compositions and methods for treating cancer

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CN114206936A CN114206936A (zh) 2022-03-18
CN114206936B true CN114206936B (zh) 2025-01-03

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US (1) US20220280567A1 (https=)
EP (1) EP3983445A4 (https=)
JP (1) JP7649258B2 (https=)
KR (1) KR20220033485A (https=)
CN (1) CN114206936B (https=)
AU (1) AU2020291922A1 (https=)
BR (1) BR112021025259A2 (https=)
CA (1) CA3143248A1 (https=)
IL (1) IL288914A (https=)
MA (1) MA56212A (https=)
MX (1) MX2021015495A (https=)
WO (1) WO2020252110A1 (https=)

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JP2024503508A (ja) 2021-01-15 2024-01-25 シージェン インコーポレイテッド 免疫調節性抗体－薬物コンジュゲート
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IL310550A (en) * 2021-08-04 2024-03-01 Univ Colorado Regents LAT-activating chimeric antigen receptor T cells and methods of using them
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CA3255500A1 (en) 2022-04-08 2023-10-12 Regeneron Pharmaceuticals, Inc. MULTI-PART RECEIVERS AND SIGNALING COMPLEXES
EP4518905A1 (en) 2022-05-06 2025-03-12 Seagen Inc. Immunomodulatory antibody-drug conjugates
JP2025520227A (ja) 2022-05-26 2025-07-02 リジェネロン・ファーマシューティカルズ・インコーポレイテッド レンチウイルスベクターを維持するための組成物及びその使用
JP2025525904A (ja) 2022-08-03 2025-08-07 シージェン インコーポレイテッド 免疫刺激性抗ｐｄ－ｌ１－薬物コンジュゲート
EP4321522A1 (en) 2022-08-12 2024-02-14 Seagen Inc. Cytotoxic compounds and conjugates thereof

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US20220280567A1 (en) 2022-09-08
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EP3983445A1 (en) 2022-04-20
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AU2020291922A1 (en) 2022-02-10
EP3983445A4 (en) 2023-06-21
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JP7649258B2 (ja) 2025-03-19
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