AU2020291922A1 - Compositions and methods for treating cancer - Google Patents

Compositions and methods for treating cancer Download PDF

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Publication number
AU2020291922A1
AU2020291922A1 AU2020291922A AU2020291922A AU2020291922A1 AU 2020291922 A1 AU2020291922 A1 AU 2020291922A1 AU 2020291922 A AU2020291922 A AU 2020291922A AU 2020291922 A AU2020291922 A AU 2020291922A AU 2020291922 A1 AU2020291922 A1 AU 2020291922A1
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Prior art keywords
cell
cells
cd79a
seq
set forth
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AU2020291922A
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Inventor
Kevin FRIEDMAN
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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Publication of AU2020291922A1 publication Critical patent/AU2020291922A1/en
Assigned to REGENERON PHARMACEUTICALS, INC. reassignment REGENERON PHARMACEUTICALS, INC. Request for Assignment Assignors: 2SEVENTY BIO, INC.
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    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/00Cellular immunotherapy
    • A61K40/30Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31Chimeric antigen receptors [CAR]
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    • A61K40/00Cellular immunotherapy
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    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
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    • A61K40/42Cancer antigens
    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
    • A61K40/421Immunoglobulin superfamily
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    • A61K40/00Cellular immunotherapy
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    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
    • A61K40/4221CD20
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    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
    • A61K40/4224Molecules with a "CD" designation not provided for elsewhere
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    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • A61K2239/28Expressing multiple CARs, TCRs or antigens
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AU2020291922A 2019-06-14 2020-06-11 Compositions and methods for treating cancer Pending AU2020291922A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962861838P 2019-06-14 2019-06-14
US62/861,838 2019-06-14
US202062991314P 2020-03-18 2020-03-18
US62/991,314 2020-03-18
PCT/US2020/037145 WO2020252110A1 (en) 2019-06-14 2020-06-11 Compositions and methods for treating cancer

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AU2020291922A1 true AU2020291922A1 (en) 2022-02-10

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AU2020291922A Pending AU2020291922A1 (en) 2019-06-14 2020-06-11 Compositions and methods for treating cancer

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US (1) US20220280567A1 (https=)
EP (1) EP3983445A4 (https=)
JP (1) JP7649258B2 (https=)
KR (1) KR20220033485A (https=)
CN (1) CN114206936B (https=)
AU (1) AU2020291922A1 (https=)
BR (1) BR112021025259A2 (https=)
CA (1) CA3143248A1 (https=)
IL (1) IL288914A (https=)
MA (1) MA56212A (https=)
MX (1) MX2021015495A (https=)
WO (1) WO2020252110A1 (https=)

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JP2024503508A (ja) 2021-01-15 2024-01-25 シージェン インコーポレイテッド 免疫調節性抗体-薬物コンジュゲート
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EP4518905A1 (en) 2022-05-06 2025-03-12 Seagen Inc. Immunomodulatory antibody-drug conjugates
JP2025520227A (ja) 2022-05-26 2025-07-02 リジェネロン・ファーマシューティカルズ・インコーポレイテッド レンチウイルスベクターを維持するための組成物及びその使用
JP2025525904A (ja) 2022-08-03 2025-08-07 シージェン インコーポレイテッド 免疫刺激性抗pd-l1-薬物コンジュゲート
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CA3143248A1 (en) 2020-12-17
CN114206936A (zh) 2022-03-18
IL288914A (en) 2022-02-01
KR20220033485A (ko) 2022-03-16
US20220280567A1 (en) 2022-09-08
WO2020252110A1 (en) 2020-12-17
JP2022537159A (ja) 2022-08-24
EP3983445A1 (en) 2022-04-20
BR112021025259A2 (pt) 2022-03-15
EP3983445A4 (en) 2023-06-21
MX2021015495A (es) 2022-04-18
JP7649258B2 (ja) 2025-03-19
MA56212A (fr) 2022-04-20
CN114206936B (zh) 2025-01-03

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