CN1141972C - 一种具有皮肤消毒作用的蒙药擦剂 - Google Patents

一种具有皮肤消毒作用的蒙药擦剂 Download PDF

Info

Publication number
CN1141972C
CN1141972C CNB021003939A CN02100393A CN1141972C CN 1141972 C CN1141972 C CN 1141972C CN B021003939 A CNB021003939 A CN B021003939A CN 02100393 A CN02100393 A CN 02100393A CN 1141972 C CN1141972 C CN 1141972C
Authority
CN
China
Prior art keywords
portions
weight portion
weight
medicine
fructus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB021003939A
Other languages
English (en)
Other versions
CN1363379A (zh
Inventor
杨文喜
姜素清
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CNB021003939A priority Critical patent/CN1141972C/zh
Publication of CN1363379A publication Critical patent/CN1363379A/zh
Application granted granted Critical
Publication of CN1141972C publication Critical patent/CN1141972C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

本发明公开发一种皮肤消毒擦剂，该外用药物是由黄柏10-50重量份；苦参10-50重量份；蛇床子10-40重量份；地肤子10-40重量份；败酱草10-40重量份；龙胆草10-50重量份；马齿苋10-50重量份；川椒10-30重量份；硼砂1-10重量份；木鳖子仁10-40重量份；红花10-40重量份；黑云香10-40重量份；组成的。该药物组检测表明具有很强的杀菌作用且无毒副作用，为纯天然药物。

Description

一种具有皮肤消毒作用的蒙药擦剂
技术领域
本发明涉及一种中药外用药，特别是涉及一种具有皮肤消毒作用的蒙药擦剂。
背景技术
目前，以中蒙药复配的植物消毒剂正在逐步成为皮肤粘膜消毒的新方向。通过总结前人的经验和查阅大量的文献资料，使祖国传统蒙药进入消毒领域也是目前一个发展趋势，中蒙药提取液具有一定的杀菌能力，且对皮肤、粘膜刺激小，属无毒和绿色环保型消毒剂，这种理念正在被消费者逐步接受。目前医疗机构对皮肤、粘膜消毒基本上使用化学类消毒剂，发展植物类消毒剂符合绿色环保要求，同时对细菌繁殖体及真菌能达到消毒效果，现代研究表明黄柏中的小檗碱、苦参中的苦参碱和蛇床子中的蛇床素等均为天然杀菌有效成分。
技术内容
本发明目的在于提供一种纯天然原料制作，无毒副作用的蒙药外用消毒擦剂。
本发明目的是通过如下技术方案实现的：选取原料药：
黄柏   10-50重量份                    苦参     10-50重量份
蛇床子 10-40重量份                    地肤子   10-40重量份
败酱草 10-40重量份                    龙胆草   10-50重量份
马齿苋 10-50重量份                    川椒     10-30重量份
硼砂   1-10重量份                     木鳖子仁 10-40重量份
红花   10-40重量份                    黑云香   10-40重量份
按常规工艺制成外用药剂。用本发明组合物制备的外用皮肤消毒擦剂“好得乐”经检测，具有很好的杀菌效果。
一、材料：
1、样品：“好得乐”消毒擦剂。
2、中和剂：1.5％吐温-80+0.5％卵磷脂的PBS。
3、试验菌：金黄色葡萄球菌(ATCC6538)菌液含1％蛋白胨。
二、方法：
参照《消毒技术规范》1999.11版悬液定量杀菌试验进行。
取含1％蛋白胨菌液0.1ml加入5.0ml消毒液中，作用一定时间后，取出菌药混合液0.5ml加入4.5ml中和剂中，中和10分钟，取稀释液接种平皿，37℃培养48小时，进行活菌计数，同时用PBC代替消毒剂作阳性对照。以3次试验的平均杀灭率报告结果。
三、结果：(见表1、2)
                表1 杀菌试验测定结果
          作用不同时间(min)的杀灭率(％)    对照回收菌数药物浓度
           3        5        7        9      (cfu/ml)
1∶2     99.84    99.98    99.99    100.00
1∶3     99.69    99.76    99.86    99.96    1.51×106
1∶4     99.35    99.70    99.79    99.87
                 表2 杀菌试验测定结果
          作用不同时间(min)的杀灭率(％)    对照回收菌数药物浓度
           3        5        7        9      (cfu/ml)
1∶2     99.87    99.98    99.99    100.00
1∶3     99.77    99.82    99.88    99.95    1.86×106
1∶4     99.60    99.78    99.84    99.89四、结论：
由表1可见“好得乐”消毒擦剂1∶3、1∶2稀释液作用9分钟，对金黄色葡萄球菌杀灭率分别为99.96％和100％。
由表2可见“好得乐”消毒擦剂1∶3、1∶2稀释液作用9分钟，对大肠杆菌杀灭率分别为99.95％和100％。
实施例：
取原料药：
黄柏30g                             苦参30g
蛇床子30g                           地肤子20g
败酱草20g                           龙胆草30g
马齿苋30g                           川椒15g
硼砂5g                          木鳖子仁25g
红花20g                         黑云香20g
将上述原料药经水煎煮2次，每次1.5小时，合并各水提液，浓缩，加入相当水提液1.2倍量的95％乙醇，放置24小时，回收乙醇，将水提醇沉液浓缩至700ml，消毒，制成外用擦剂，每瓶100ml。

Claims (2)

1、一种皮肤消毒药物，其特征在于该药物是由下列原料药制成的：
黄柏   10-50重量份                    苦参     10-50重量份
蛇床子 10-40重量份                    地肤子   10-40重量份
败酱草 10-40重量份                    龙胆草   10-50重量份
马齿苋 10-50重量份                    川椒     10-30重量份
硼砂   1-10重量份                     木鳖子仁 10-40重量份
红花   10-40重量份                    黑云香   10-40重量份。
2、如权利要求书所述的药物，其特征在于该药物是由下列原料药制成的：
黄柏   30重量份                       苦参     30重量份
蛇床子 30重量份                       地肤子   20重量份
败酱草 20重量份                       龙胆草   30重量份
马齿苋 30重量份                       川椒     15重量份
硼砂   5重量份                        木鳖子仁 25重量份
红花   20重量份                       黑云香   20重量份。
CNB021003939A 2002-01-21 2002-01-21 一种具有皮肤消毒作用的蒙药擦剂 Expired - Fee Related CN1141972C (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB021003939A CN1141972C (zh) 2002-01-21 2002-01-21 一种具有皮肤消毒作用的蒙药擦剂

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB021003939A CN1141972C (zh) 2002-01-21 2002-01-21 一种具有皮肤消毒作用的蒙药擦剂

Publications (2)

Publication Number Publication Date
CN1363379A CN1363379A (zh) 2002-08-14
CN1141972C true CN1141972C (zh) 2004-03-17

Family

ID=4739342

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB021003939A Expired - Fee Related CN1141972C (zh) 2002-01-21 2002-01-21 一种具有皮肤消毒作用的蒙药擦剂

Country Status (1)

Country Link
CN (1) CN1141972C (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102423291A (zh) * 2011-12-30 2012-04-25 山西振东制药股份有限公司 一种中药抗菌护肤洗手液及其制备方法
CN104922449A (zh) * 2015-05-26 2015-09-23 青岛海之星生物科技有限公司 一种中药消毒液及其制备方法

Also Published As

Publication number Publication date
CN1363379A (zh) 2002-08-14

Similar Documents

Publication Publication Date Title
Vasudeva et al. Disinfection of dentinal tubules with 2% Chlorhexidine gel, Calcium hydroxide and herbal intracanal medicaments against Enterococcus faecalis: An in-vitro study
Bazvand et al. Antibacterial effect of triantibiotic mixture, chlorhexidine gel, and two natural materials Propolis and Aloe vera against Enterococcus faecalis: An ex vivo study
Garg et al. Comparison of antimicrobial efficacy of propolis, Morinda citrifolia, Azadirachta indica, triphala, green tea polyphenols and 5.25% sodium hypochlorite against Enterococcus fecalis biofilm
De Lucena et al. Antimicrobial effectiveness of intracanal medicaments on E nterococcus faecalis: chlorhexidine versus octenidine
CN102552775B (zh) 消毒液
Raoof et al. Antimicrobial activity of methanolic extracts of Myrtus communis L. and Eucalyptus galbie and their combination with calcium hydroxide powder against Enterococcus faecalis
Bhandari et al. An in vitro evaluation of antimicrobial efficacy of 2% chlorhexidine gel, propolis and calcium hydroxide against Enterococcus faecalis in human root dentin
Jolly et al. Propolis and commonly used intracanal irrigants.: Comparative evaluation of antimicrobial potential
CN104523545A (zh) 一种抗菌护肤手消毒液及其制备方法
Dedhia et al. Efficacy of Andrographis paniculata compared to Azadirachta indica, Curcuma longa, and sodium hypochlorite when used as root canal irrigants against Candida albicans and Staphylococcus aureus: An: in vitro: antimicrobial study
Thangavelu et al. Antimicrobial properties of silver nitrate nanoparticle and its application in endodontics and dentistry: a review of literature
Valera et al. Action of chlorhexidine, Zingiber officinale, and calcium hydroxide on Candida albicans, Enterococcus faecalis, Escherichia coli, and endotoxin in the root canals
Sinha et al. Dentinal tubule disinfection with propolis & two extracts of Azadirachta indica against Candida albicans biofilm formed on tooth substrate
Taiwo et al. Consumption of aqueous extract of raw Aloe vera leaves: histopathological and biochemical studies in rat and tilapia
CN108041104A (zh) 一种检验科用中药复合型消毒液及其制备方法
CN1141972C (zh) 一种具有皮肤消毒作用的蒙药擦剂
Sailaja et al. Comparative Evaluation of Various Herbal and Synthetic Solutions On Disinfection Of Guttapercha: An: In Vitro: Study
CN109362797A (zh) 碘消毒液及其制备方法
CN105012581A (zh) 一种芦荟舒爽抑菌组合物、应用及其制备方法
CN108853358A (zh) 一种抗菌中药组合物及其制备方法和用途
Almansour et al. Histomorphometric alterations induced in the testicular tissues by variable sizes of silver nanoparticles
CN104147076A (zh) 一种抑制藤黄微球菌的金银花抑菌剂
Malik et al. Antimicrobial effects of essential oils against uropathogens with varying sensitivity to antibiotics
CN101028532A (zh) 植物精油空气消毒清新剂
Shenoy et al. Assessment of precipitate formation on interaction of irrigants used in different combinations: An: in vitro: study

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee