CN114191718B - Electric field generating electrode paste and tumor electric field treatment device - Google Patents
Electric field generating electrode paste and tumor electric field treatment device Download PDFInfo
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- CN114191718B CN114191718B CN202210142550.1A CN202210142550A CN114191718B CN 114191718 B CN114191718 B CN 114191718B CN 202210142550 A CN202210142550 A CN 202210142550A CN 114191718 B CN114191718 B CN 114191718B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
- A61N1/36002—Cancer treatment, e.g. tumour
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/048—Electrodes characterised by a specific connection between lead and electrode
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0472—Structure-related aspects
- A61N1/0492—Patch electrodes
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K7/00—Constructional details common to different types of electric apparatus
- H05K7/20—Modifications to facilitate cooling, ventilating, or heating
- H05K7/20218—Modifications to facilitate cooling, ventilating, or heating using a liquid coolant without phase change in electronic enclosures
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- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05K—PRINTED CIRCUITS; CASINGS OR CONSTRUCTIONAL DETAILS OF ELECTRIC APPARATUS; MANUFACTURE OF ASSEMBLAGES OF ELECTRICAL COMPONENTS
- H05K7/00—Constructional details common to different types of electric apparatus
- H05K7/20—Modifications to facilitate cooling, ventilating, or heating
- H05K7/2039—Modifications to facilitate cooling, ventilating, or heating characterised by the heat transfer by conduction from the heat generating element to a dissipating body
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Abstract
The application provides an electric field generating electrode paste and a tumor electric field treatment device, wherein the electric field generating electrode paste comprises a substrate, cooling liquid is contained in the substrate, one surface of the substrate is provided with k hole groups, and k is an integer not less than 1; the hole group comprises at least one hole; each hole is hermetically connected with a refrigerating sheet; the heat dissipation end of each refrigeration piece is in heat conduction connection with the cooling liquid, and the heat absorption end of each refrigeration piece is provided with an electric field generation piece; the electric field generating piece is used for applying a designed electric field to the target biological tissue; each electric field generating piece and each refrigerating piece are electrically connected with the host. This application utilizes the coolant liquid and the refrigeration piece of base to take place a heat dissipation for the electric field, has solved the electric field and has taken place a long-time work and be difficult to radiating problem.
Description
Technical Field
The application relates to the field of surgery, in particular to an electric field generating electrode paste and a tumor electric field treatment device.
Background
Tumor electric field therapy (TTF) is a therapeutic approach to inhibit cancer cell proliferation by disrupting the mitosis that destroys cancer cells. At present, in the process of tumor electric field therapy, two electrode patches are mainly attached to a target organism such as a human body, and an electric field is coupled to a target organism tissue, such as an affected part of the target organism, through the electrode patches.
However, in the course of electric field treatment of tumors, a large amount of heat is generated, which increases the surface temperature of the biological tissue and affects the physiological environment of the biological tissue. Namely, the existing tumor electric field treatment still has the problem of difficult heat dissipation.
Disclosure of Invention
The application provides an electric field generating electrode paste and a tumor electric field treatment device aiming at the defects of the prior art, and is used for solving the technical problem that the tumor electric field treatment in the prior art has difficulty in heat dissipation.
In a first aspect, an embodiment of the present application provides an electric field generating electrode patch, including a substrate, where the substrate contains a cooling liquid, one surface of the substrate is provided with k hole groups, and k is an integer not less than 1; the hole group comprises at least one hole; each hole is hermetically connected with a refrigerating sheet; the heat dissipation end of each refrigeration piece is in heat conduction connection with the cooling liquid, and the heat absorption end of each refrigeration piece is provided with an electric field generation piece; the electric field generating piece is used for applying a designed electric field to the target biological tissue; each electric field generating piece and each refrigerating piece are electrically connected with the host.
Optionally, the hole group includes n rows and m columns of holes, where n and m are integers not less than 1.
Optionally, a thermosensitive element is further included for detecting the temperature of the target biological tissue.
Optionally, each of the electric field generating members is stacked with a conductive paste, and a thermosensitive element is disposed between each of the conductive paste and the electric field generating member.
Optionally, the wire harness further comprises a first wire group, a second wire group and a third wire group; each electric field generating piece is electrically connected with a first lead in the first lead group one by one, each refrigeration piece is electrically connected with a second lead in the second lead group one by one, and each thermosensitive element is electrically connected with a third lead in the third lead group one by one; the first lead group, the second lead group and the third lead group are all arranged on the substrate.
Optionally, the electric field generating member includes a conductive plate and a dielectric plate stacked together, and the conductive plate is connected to the heat absorbing end of the refrigeration plate.
Optionally, a magic tape is further disposed on the substrate, and is used for wearing the electric field generating electrode on a biological surface corresponding to the target biological tissue.
Optionally, the substrate is shaped as a strip or vest.
Optionally, the refrigerator further comprises a heat conducting fin, a first surface of the heat conducting fin is connected with the hole in a sealing mode, the cooling liquid is in contact with the first surface of the heat conducting fin, and a second surface of the heat conducting fin is connected with the heat dissipation end of the refrigeration fin.
Optionally, one side of the substrate is provided with k hole groups, where k is 1.
In a second aspect, an embodiment of the present application provides a tumor electric field treatment device, which includes a host and the electric field generating electrode paste of the first aspect, where k in the electric field generating electrode paste is an integer not less than 2, and an electric field generating piece, a refrigerating sheet, and a thermosensitive element in the electric field generating electrode paste are all electrically connected to the host.
Optionally, the thermosensitive element is configured to transmit detected temperature data of the target biological tissue to the host, and the host is configured to output a first signal to the refrigeration sheet when the temperature data is greater than a first design temperature, so that the refrigeration sheet is turned on to cool the electric field generating member; when the temperature data is lower than a second design temperature, outputting a second signal to the refrigerating sheet to close the refrigerating sheet; the second design temperature is less than the first design temperature.
In a third aspect, an embodiment of the present invention provides another tumor electric field treatment apparatus, including a host and at least one pair of electric field generating electrode patches described in the first aspect, where k in the electric field generating electrode patch is 1; the electric field generating piece, the refrigerating piece and the thermosensitive element in each electric field generating electrode paste are electrically connected with the host machine.
The utility model provides a pair of electrode subsides take place for electric field, the electric field takes place the piece and applys the design electric field for target biological tissue, along with operating time increases, the piece constantly produces the heat takes place for the electric field, take place a piece with the electric field because of the heat absorption end of refrigeration piece and be connected, the heat that the piece produced takes place for the electric field can in time be given the refrigeration piece, and the cooling liquid in the basement is given in the heat dissipation end transmission through the refrigeration piece, the cooling liquid utilizes the great surface area of basement to dispel the heat to external environment. This application can take place the piece to the electric field through the coolant liquid that utilizes the base and the refrigeration piece and carry out timely effectual heat dissipation for the electric field takes place even long-time work also can maintain at reasonable temperature range.
The foregoing description is only an overview of the technical solutions of the embodiments of the present application, and the embodiments of the present application can be implemented according to the content of the description in order to make the technical means of the embodiments of the present application more clearly understood, and the detailed description of the embodiments of the present application will be given below in order to make the foregoing and other objects, features, and advantages of the embodiments of the present application more clearly understandable.
Drawings
The foregoing and/or additional aspects and advantages of the present application will become apparent and readily appreciated from the following description of the embodiments, taken in conjunction with the accompanying drawings of which:
fig. 1 is a schematic structural diagram of an electric field generating electrode patch according to an embodiment of the present disclosure;
FIG. 2 isbase:Sub>A schematic cross-sectional view taken at A-A in FIG. 1;
FIG. 3 is another schematic cross-sectional view taken at A-A of FIG. 1;
FIG. 4 isbase:Sub>A schematic cross-sectional view taken at A-A in FIG. 1;
FIG. 5 isbase:Sub>A schematic cross-sectional view taken at A-A in FIG. 1;
FIG. 6 isbase:Sub>A schematic cross-sectional view taken at A-A in FIG. 1;
fig. 7 is a schematic structural diagram of an electric field generating electrode patch according to an embodiment of the present disclosure, in which a hole group is formed on one surface of a substrate;
fig. 8 is a schematic structural diagram of an electric field generating electrode sticker in which one surface of a substrate is provided with four hole groups according to an embodiment of the present application;
FIG. 9 is a schematic view of another side of the electric field generating electrode patch of FIG. 8;
FIG. 10 is a schematic structural diagram of an electric field tumor therapy apparatus according to an embodiment of the present disclosure;
fig. 11 is a schematic structural diagram of another tumor electric field treatment device according to an embodiment of the present application.
The reference numerals are introduced as follows:
1-sticking an electric field generating electrode; 11-a substrate; 111-cooling liquid; 12-a group of holes; 121-holes; 13-a refrigerating sheet; 14-an electric field generating member; 141-a conductive sheet; 142-a dielectric sheet; 15-a thermo-sensitive element; 16-conductive application; 171-a first magic tape; 172-a second magic tape; 18-a thermally conductive sheet;
2-a host;
100-tumor electric field treatment device.
Detailed Description
The present application is described in detail below and examples of embodiments of the present application are illustrated in the accompanying drawings, wherein like reference numerals refer to the same or similar elements or elements with the same or similar functionality throughout. In addition, if a detailed description of the known art is unnecessary for the features of the present application shown, it is omitted. The embodiments described below with reference to the drawings are exemplary only for the purpose of explaining the present application and are not to be construed as limiting the present application.
It will be understood by those within the art that, unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the prior art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
As used herein, the singular forms "a", "an", "the" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof. It will be understood that when an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. Further, "connected" as used herein may include wirelessly connected. As used herein, the term "and/or" includes all or any element and all combinations of one or more of the associated listed items.
At present, in the process of tumor electric field therapy, two electrode patches are mainly attached to a target organism such as a human body, and an electric field is coupled to a target organism tissue, such as an affected part of the target organism, through the electrode patches.
However, in the course of tumor electric field therapy, a large amount of heat is generated, which increases the surface temperature of the biological tissue, thereby affecting the physiological environment of the biological tissue. Namely, the existing tumor electric field treatment still has the problem of difficult heat dissipation.
The following describes the technical solutions of the present application and how to solve the above technical problems with specific embodiments. It should be noted that the dashed line boxes in fig. 1, 7, 8, 10, and 11 do not actually exist, but are provided for the purpose of specifying the hole group.
The embodiment of the application provides an electric field generating electrode paste 1, which is shown in reference to fig. 1 and fig. 2 and comprises a substrate 11, wherein the substrate 11 contains cooling liquid 111, one surface of the substrate 11 is provided with k hole groups 12, and k is an integer not less than 1; the set of holes 12 comprises at least one hole 121; each hole 121 is hermetically connected with a refrigerating sheet 13; the heat dissipation end of each refrigeration sheet 13 is in heat conduction connection with the cooling liquid 111, and the heat absorption end of each refrigeration sheet 13 is provided with an electric field generation piece 14; the electric-field generating member 14 is used for applying a designed electric field to a target biological tissue; each electric field generating piece 14 and each refrigerating sheet 13 are used for being electrically connected with the main machine 2.
In this embodiment, the electric field generating element 14 applies a designed electric field to the target biological tissue, and as the operating time increases, the electric field generating element 14 continuously generates heat, and as the heat absorbing end of the cooling fin 13 is connected to the electric field generating element 14, the heat generated by the electric field generating element 14 can be timely transmitted to the cooling fin 13 and transmitted to the cooling liquid 111 in the substrate 11 through the heat dissipating end of the cooling fin 13, and the cooling liquid 111 dissipates heat to the external environment by using the larger surface area of the substrate. The process utilizes the cooling liquid 111 and the cooling fins 13 of the base 11 to effectively dissipate heat of the electric field generating member 14 in time, so that the electric field generating member 14 can be maintained in a reasonable temperature range even if the electric field generating member is operated for a long time.
After the electric field generating member 14 is cooled, the target living body feels more comfortable during the treatment of the target living body tissue, and the influence on the physiological environment of the target living body, such as the abnormality of the functions of body temperature regulation, water and salt metabolism or blood circulation, etc., and the occurrence of side effects of rash, ulcer, etc., caused by the heat generated by the electric field generating member 14 can be prevented.
Alternatively, the target biological tissue may include a tumor of the thoracic cavity, and the electric field generating electrode patch 1 may be applied to a tumor treatment of the thoracic cavity, such as a lung tumor, a liver tumor, or the like.
Alternatively, the base 11 may comprise a container bag, the interior of which is filled with a cooling liquid and no gas is present.
Optionally, the hole group 12 includes n rows and m columns of holes 121, where n and m are integers not less than 1.
In this embodiment, the hole group 12 includes n rows and m columns of holes 121, where n and m are integers not less than 1, specifically, 3 rows and 3 columns, 4 rows and 4 cases, 5 rows and 5 columns, and the like. Referring to fig. 1, the hole group 12 includes 4 rows and 4 columns of holes 121, each hole 121 in adjacent rows may be disposed oppositely, and each hole 121 in adjacent columns may also be disposed oppositely.
Alternatively, the hole group 12 may include a plurality of holes 121 arranged in a circle, a regular polygon, a rectangle or a prism, or a plurality of holes 121 arranged in other combinations.
Optionally, the electric field generating electrode patch 1 further comprises a thermosensitive element 15, and the thermosensitive element 15 is used for detecting the temperature of the target biological tissue. The heat sensitive element 15 may be a thermistor.
In this embodiment, the thermal sensitive element 15 is used to detect the temperature of the target biological tissue, so as to open the refrigeration sheet 13 in time to absorb the heat generated by the electric field generating member 14, thereby cooling the surface of the target biological tissue.
The specific position of the thermosensitive element 15 is not limited at all, and may be set according to actual needs.
In one embodiment, as shown in fig. 3, the position of the thermal sensitive element 15 is arranged at the center of the electric field generating member 14, so that the temperature of the biological surface can be measured, and the measured temperature data is more accurate.
In another embodiment, as shown in fig. 4, the thermosensitive element 15 is positioned between the two electric field generating members 14 for easy installation.
In yet another embodiment, as shown in FIG. 5, the heat sensitive element 15 is positioned on the base 11 for easy installation.
Alternatively, as shown in FIG. 6, each of the electric field generating members 14 is laminated with a conductive application 16, and a thermosensitive element 15 is provided between each of the conductive application 16 and the electric field generating member 14.
In this embodiment, the conductive patch 16 is laminated on one side of the electric field generator 14, and the electric field generator 14 is hard, so that the living body is likely to feel uncomfortable if the electric field generator 14 is in direct contact with the living body surface, and therefore the electric field generator 14 does not directly contact with the living body surface, but acts on the living body surface through the conductive patch 16, thereby increasing the comfort of the living body. In particular, the conductive patch 16 may be a conductive gel.
Optionally, the electric field generating electrode sticker 1 further includes a first lead group, a second lead group and a third lead group; each electric field generating piece 14 is electrically connected with a first lead wire in the first lead wire group one by one, each refrigerating piece 13 is electrically connected with a second lead wire in the second lead wire group one by one, and each thermosensitive element 15 is electrically connected with a third lead wire in the third lead wire group one by one; the first, second, and third lead groups are disposed on the substrate 11.
Alternatively, as shown in fig. 6, the electric field generating member 14 includes a conductive plate 141 and a dielectric plate 142, which are stacked, and the conductive plate 141 is connected to the heat absorbing end of the cooling plate 13.
In this embodiment, one surface of the conductive plate 141 is connected to the heat absorbing end of the cooling plate 13, and the other surface is connected to the dielectric plate 142 in an overlapping manner. The dielectric sheet 142 is specifically a ceramic sheet, and the dielectric sheet 142 and the conductive sheet 141 are coupled to function as a capacitor.
Optionally, as shown in fig. 8 and 9, a magic tape is further disposed on the substrate 11 for wearing the electric field generating electrode patch 1 on the biological surface corresponding to the target biological tissue.
In this embodiment, the magic tape is disposed on the substrate 11, so that the electric field generating electrode tape 1 can be worn on the biological surface corresponding to the target biological tissue, that is, the wearing mode of the electric field generating electrode tape 1 replaces the existing sticking type electrode tape.
Optionally, as shown in fig. 8 and 9, the magic tape includes a first magic tape 171 and a second magic tape 172, the first magic tape 171 is disposed at a first end portion of one side of the substrate 11 where the cooling fins 13 are disposed, the second magic tape 172 is disposed at a second end portion of the other side of the substrate 11, and the first end portion and the second end portion are opposite sides of the substrate 11.
In this embodiment, the first end portion and the second end portion of the two opposite sides of the substrate 11 are respectively provided with the first magic tape 171 and the second magic tape 172, so that when the electric field generating electrode tape 1 is worn on the biological surface corresponding to the target biological tissue, the electric field generating electrode tape 1 is conveniently fixed on the biological surface corresponding to the target biological tissue by the mutual matching of the first magic tape 171 and the second magic tape 172.
Alternatively, the shape of the substrate 11 is a strip shape or a vest shape.
In this embodiment, the shape of the substrate 11 may be set according to actual requirements, and specifically, the shape of the substrate 11 may be a strip shape or a waistcoat shape, which are both convenient to wear.
Optionally, with continued reference to fig. 6, the electric field generating electrode patch 1 further includes a heat conducting plate 18, a first surface of the heat conducting plate 18 is hermetically connected to the hole 121, the cooling liquid 111 contacts the first surface of the heat conducting plate 18, and a second surface of the heat conducting plate 18 is connected to the heat dissipating end of the cooling plate 13.
In this embodiment, the cooling fins 13 conduct heat with the cooling liquid 111 through the heat conducting fins 18, and the heat conducting fins 18 directly contact with the cooling liquid 111, so as to accelerate the cooling speed; the first surface of the heat-conducting sheet 18 is hermetically connected to the hole 121, thereby preventing the coolant 111 from leaking.
Alternatively, as shown in FIG. 7, one side of the substrate 11 is provided with k sets of holes 12, k being 1.
In this embodiment, the substrate 11 is provided with 1 hole group 12.
Optionally, as shown in fig. 8, in the embodiment, one surface of the substrate 11 is provided with 4 hole groups 12, and for convenience of description, a direction parallel to the substrate 11 is set as a first direction, a direction parallel to the substrate 11 and perpendicular to the first direction is set as a second direction, the first direction is a row direction of the hole groups 12, and the second direction is a column direction of the hole groups 12.
Optionally, as shown in fig. 8, the hole group 12 includes 4 rows and 4 columns of holes 121, the number of the holes 121 from the 1 st row to the 4 th row is 4 in sequence, and the holes 121 in two adjacent rows are disposed oppositely, accordingly, the number of the holes 121 from the 1 st column to the 4 th column is 4 in sequence, and the holes 121 in two adjacent columns are disposed oppositely.
Based on the same concept, an embodiment of the present application provides a tumor electric field treatment apparatus 100, as shown in fig. 10, including a host machine 2 and the electric field generating electrode paste 1 of the above embodiment, where k in the electric field generating electrode paste 1 is an integer not less than 2, and the electric field generating element 14, the refrigerating sheet 13 and the thermosensitive element 15 in the electric field generating electrode paste 1 are all electrically connected to the host machine 2.
In this embodiment, the main body 2 is electrically connected to the electric field generator 14, the refrigerating sheet 13 and the heat sensitive element 15 through the wire group.
In an alternative embodiment, the host 2 may include a generating device, a controller, and a power supply device. The generating device, the controller and the power supply device are electrically connected in pairs.
The power supply device is respectively and electrically connected with the electric field generating piece 14, the refrigerating piece 13 and the thermosensitive element 15 and is used for providing required electric energy for the generating device, the controller, the electric field generating piece 14, the refrigerating piece 13 and the thermosensitive element 15.
The generating device is electrically connected with the electric field generating element 14 and outputs signals to the electric field generating element 14, and the electric field generating element 14 emits corresponding electric fields to the target biological tissues to act on the target biological tissues.
The controller is respectively electrically connected with the thermosensitive element 15 and the refrigerating sheet 13 and is used for receiving the temperature data of the target biological tissues detected by the thermosensitive element 15 and controlling the opening and closing of the refrigerating sheet 13 according to the relation between the temperature data and the design temperature.
Optionally, the thermosensitive element 15 is configured to transmit the detected temperature data of the target biological tissue to the host 2, and the host 2 is configured to output a first signal to the cooling plate 13 when the temperature data is greater than a first design temperature, so that the cooling plate 13 is turned on to cool the electric field generating element 14; when the temperature data is lower than the second design temperature, outputting a second signal to the refrigerating sheet 13 to close the refrigerating sheet 13; the second design temperature is less than the first design temperature.
In this embodiment, the first design temperature may be a relatively large temperature that the surface of the target biological tissue can bear, and the first design temperature may be between 36 ℃ and 42 ℃, for example, 36 ℃, 38 ℃, 40 ℃ or 42 ℃, and when the detected temperature data exceeds the first design temperature, the target biological tissue may feel uncomfortable, so when the detected temperature data is greater than the first design temperature, the cooling fins 13 are turned on, the heat absorbing ends of the cooling fins 13 absorb the heat generated by the electric field generating member 14, and the heat is transferred to the heat conducting fins 18 through the heat dissipating ends of the cooling fins 13, the heat conducting fins 18 are in contact with the cooling liquid 111 in the substrate 11, and the heat is dissipated through the cooling liquid 111, and in this process, the temperature of the electric field generating member 14 can be rapidly reduced, and the temperature of the target biological tissue feels comfortable.
The second design temperature may be a smaller temperature that the surface of the target biological tissue can bear, and the second design temperature may be between 25 ℃ and 30 ℃, for example, 25 ℃, 27 ℃, 28 ℃ or 30 ℃, and the target biological tissue may feel uncomfortable after the detected temperature data is lower than the second design temperature, so that when the detected temperature data is lower than the second design temperature, the cooling plate 13 is turned off, and the electric field generating member 14 does not need to be cooled.
Based on the same conception, the present embodiment provides another tumor electric field treatment apparatus 100, as shown in fig. 11, which includes a main machine 2 and a pair of electric field generating electrode pastes 1 of the above embodiments, one surface of a substrate 11 of the electric field generating electrode paste 1 is provided with a hole group 12, and an electric field generating part 14, a refrigerating plate 13 and a thermosensitive element 15 in each electric field generating electrode paste 1 are electrically connected to the main machine 2.
In this embodiment, the electric field generating electrode patch 1 can be fixed on the surface of the target biological tissue by attaching a pair of substrates 11 disposed opposite to each other, thereby treating the target biological tissue.
Since the tumor electric field treatment apparatus 100 of the present embodiment includes the electric field generating electrode patch 1 of the above embodiment, the beneficial effects of the tumor electric field treatment apparatus 100 are the same as those of the electric field generating electrode patch 1, and the details are not repeated herein.
By applying the embodiment of the application, at least the following beneficial effects can be realized:
1. utilize the coolant liquid and the refrigeration piece of base to take place a heat dissipation for the electric field in the embodiment of this application, it takes away the heat that the electric field takes place a long-time work and is difficult to the radiating problem to have solved the electric field, make the in-process of target biological tissue at the treatment more comfortable, and prevent to the physiological environment production influence of biological tissue, function such as body temperature regulation, water salt metabolism or blood circulation etc. are unusual, and prevent that the electric field from taking place the rash that the heat that the piece produced causes, the emergence of side effect such as ulcer.
2. In the embodiment of the application, the electric field generating parts are laminated with the conductive application, so that the comfort of the target biological tissue is improved.
3. The mode that pastes formula electrode paster with wearing formula electric field generating electrode subsides replaces current mode of pasting formula electrode paster in this application embodiment, and the mode of wearing not only makes electric field generating electrode paste wear to take off the time of installation such as simple and convenient more, reduction equipment, still makes the biological activity of target more free, brings the biological better comfort of target.
Those of skill in the art will appreciate that the various operations, methods, steps in the processes, acts, or solutions discussed in this application can be interchanged, modified, combined, or eliminated. Further, other steps, measures, or schemes in various operations, methods, or flows that have been discussed in this application can be alternated, altered, rearranged, broken down, combined, or deleted. Further, steps, measures, schemes in the prior art having various operations, methods, procedures disclosed in the present application may also be alternated, modified, rearranged, decomposed, combined, or deleted.
In the description of the present application, it is to be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", and the like indicate orientations or positional relationships based on those shown in the drawings, and are only for convenience in describing the present application and simplifying the description, but do not indicate or imply that the referred device or element must have a particular orientation, be constructed in a particular orientation, and be operated, and thus should not be construed as limiting the present application.
The terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present application, "a plurality" means two or more unless otherwise specified.
In the description herein, particular features, structures, materials, or characteristics may be combined in any suitable manner in any one or more embodiments or examples.
It should be understood that, although the steps in the flowcharts of the figures are shown in order as indicated by the arrows, the steps are not necessarily performed in order as indicated by the arrows. The steps are not performed in the exact order shown and may be performed in other orders unless explicitly stated herein. Moreover, at least a portion of the steps in the flow chart of the figure may include multiple sub-steps or multiple stages, which are not necessarily performed at the same time, but may be performed at different times, which are not necessarily performed in sequence, but may be performed alternately or alternately with other steps or at least a portion of the sub-steps or stages of other steps.
The foregoing is only a partial embodiment of the present application, and it should be noted that, for those skilled in the art, several modifications and decorations can be made without departing from the principle of the present application, and these modifications and decorations should also be regarded as the protection scope of the present application.
Claims (12)
1. An electric field generating electrode paste is characterized by comprising a substrate, wherein the substrate comprises a container bag, the container bag is filled with cooling liquid and has no gas, one surface of the substrate is provided with k hole groups, and k is an integer not less than 1; the hole group comprises at least one hole; each hole is hermetically connected with a refrigerating sheet; the heat dissipation end of each refrigeration sheet is in heat conduction connection with the cooling liquid, and the heat absorption end of each refrigeration sheet is provided with an electric field generation piece; the electric field generating piece is used for applying a designed electric field to the target biological tissue;
the electric field generating electrode paste also comprises a first lead group, a second lead group and a third lead group; each electric field generating piece is respectively and electrically connected with a first lead in the first lead group one by one, each refrigerating piece is respectively and electrically connected with a second lead in the second lead group one by one, and each thermosensitive element in the electrode paste of the electric field is respectively and electrically connected with a third lead in the third lead group one by one; the first lead group, the second lead group and the third lead group are all arranged on the substrate;
each electric field generating piece and each refrigerating piece are electrically connected with the host.
2. The electric field generating electrode paste as claimed in claim 1, wherein the hole group comprises n rows and m columns of holes, and n and m are integers not less than 1.
3. The electric field generating electrode patch as claimed in claim 1, further comprising the thermosensitive element for detecting the temperature of the target biological tissue.
4. The electric field generating electrode paste as claimed in claim 3, wherein each of said electric field generating members is laminated with a conductive paste, and a heat sensitive element is provided between each of said conductive paste and said electric field generating member.
5. The electric field generating electrode paste as claimed in claim 1, wherein the electric field generating member comprises a conductive sheet and a dielectric sheet stacked together, and the conductive sheet is connected to the heat absorbing end of the cooling sheet.
6. The electric field generating electrode patch as claimed in claim 1, wherein a magic tape is further disposed on the substrate for wearing the electric field generating electrode patch on a biological surface corresponding to a target biological tissue.
7. The electric field generating electrode paste as claimed in claim 1, wherein the substrate has a strip shape or a waistcoat shape.
8. The electric field generating electrode paste as claimed in claim 1, further comprising a heat conducting sheet, wherein a first surface of the heat conducting sheet is hermetically connected to the hole, the coolant is in contact with the first surface of the heat conducting sheet, and a second surface of the heat conducting sheet is connected to the heat dissipating end of the refrigerating sheet.
9. The electric field generating electrode paste as claimed in claim 1, wherein k is 1.
10. An electric field treatment device for tumor, which comprises a host and the electric field generating electrode paste as claimed in any one of claims 1 to 8, wherein k in the electric field generating electrode paste is an integer not less than 2, and the electric field generating piece, the refrigerating sheet and the thermosensitive element in the electric field generating electrode paste are all electrically connected with the host.
11. The tumor electric field treatment device according to claim 10, wherein the thermosensitive element is configured to transmit the detected temperature data of the target biological tissue to the host, and the host is configured to output a first signal to the cooling plate when the temperature data is greater than a first design temperature, so that the cooling plate is turned on to cool the electric field generating member; when the temperature data is lower than a second design temperature, outputting a second signal to the refrigerating sheet to close the refrigerating sheet; the second design temperature is less than the first design temperature.
12. An electric field tumor treating device, comprising a main machine and at least one pair of electric field generating electrode patches according to claim 9; the electric field generating piece, the refrigerating piece and the thermosensitive element in each electric field generating electrode paste are electrically connected with the host machine.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113289247A (en) * | 2021-05-20 | 2021-08-24 | 杭州维那泰克医疗科技有限责任公司 | Electrode patch and cell division suppression device |
| CN113856052A (en) * | 2021-09-28 | 2021-12-31 | 江苏海莱新创医疗科技有限公司 | Active heat absorption type electrode, tumor electric field treatment system and temperature control method |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4649923A (en) * | 1985-10-16 | 1987-03-17 | Murray Electronics Associates Limited | Temperature indicating electrotherapy electrode |
| SE455920B (en) * | 1986-01-29 | 1988-08-22 | Hans Wiksell | TUMOR HYPERTERMY TREATMENT DEVICE |
| WO2006119343A1 (en) * | 2005-05-03 | 2006-11-09 | Children's Hospital Medical Center | Determination of eosinophilic esophagitis |
| CN1748814A (en) * | 2005-09-29 | 2006-03-22 | 上海奥润微纳新材料科技有限公司 | Alternating magnetic field thermotherapeutic system for tumor |
| CN100518684C (en) * | 2006-06-30 | 2009-07-29 | 南京福中信息产业集团有限公司 | Cold circulation microwave tumor therapeutic apparatus |
| US20120290049A1 (en) * | 2011-05-09 | 2012-11-15 | Michel Marc | Apparatus and Method for Providing a Substantially Constant Voltage Between Electrodes Extending Across a Treatment Region |
| US9675814B2 (en) * | 2011-05-09 | 2017-06-13 | Innovolink, Llc | Apparatus and method for obtaining a substantially constant current across a treatment region |
| US8649869B2 (en) * | 2012-03-05 | 2014-02-11 | Pacesetter, Inc. | Implantable medical device having feedthru assembly with header side bunched conductor array and can side linear conductor array |
| KR102234149B1 (en) * | 2018-09-07 | 2021-03-30 | 네오-나노메딕스.인크 | Ac magnetic field generator based on magnetic materials heating |
| US11458298B2 (en) * | 2020-01-22 | 2022-10-04 | Novocure Gmbh | Assemblies containing two conductive gel compositions and methods of production and use thereof |
| CN113476742A (en) * | 2021-08-09 | 2021-10-08 | 杭州维纳安可医疗科技有限责任公司 | System for inhibiting pathological cell division and control method thereof |
| CN113769267B (en) * | 2021-08-25 | 2024-04-26 | 杭州维纳安可医疗科技有限责任公司 | Implantable electrode capable of monitoring conductivity signal and device for inhibiting cell division |
| CN113926079A (en) * | 2021-10-15 | 2022-01-14 | 杭州维纳安可医疗科技有限责任公司 | Implantable electrode plate and control system thereof |
-
2022
- 2022-02-16 CN CN202210142550.1A patent/CN114191718B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113289247A (en) * | 2021-05-20 | 2021-08-24 | 杭州维那泰克医疗科技有限责任公司 | Electrode patch and cell division suppression device |
| CN113856052A (en) * | 2021-09-28 | 2021-12-31 | 江苏海莱新创医疗科技有限公司 | Active heat absorption type electrode, tumor electric field treatment system and temperature control method |
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