CN114177120A - Composition for lip care - Google Patents
Composition for lip care Download PDFInfo
- Publication number
- CN114177120A CN114177120A CN202111543901.1A CN202111543901A CN114177120A CN 114177120 A CN114177120 A CN 114177120A CN 202111543901 A CN202111543901 A CN 202111543901A CN 114177120 A CN114177120 A CN 114177120A
- Authority
- CN
- China
- Prior art keywords
- parts
- composition
- lip care
- lip
- beeswax
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 57
- 239000004264 Petrolatum Substances 0.000 claims abstract description 31
- 239000004480 active ingredient Substances 0.000 claims abstract description 31
- 235000013871 bee wax Nutrition 0.000 claims abstract description 31
- 239000012166 beeswax Substances 0.000 claims abstract description 31
- 229940066842 petrolatum Drugs 0.000 claims abstract description 31
- 235000019271 petrolatum Nutrition 0.000 claims abstract description 31
- 235000019519 canola oil Nutrition 0.000 claims abstract description 11
- 239000000828 canola oil Substances 0.000 claims abstract description 11
- 235000019484 Rapeseed oil Nutrition 0.000 claims description 32
- DPUOLQHDNGRHBS-UHFFFAOYSA-N Brassidinsaeure Natural products CCCCCCCCC=CCCCCCCCCCCCC(O)=O DPUOLQHDNGRHBS-UHFFFAOYSA-N 0.000 claims description 28
- URXZXNYJPAJJOQ-UHFFFAOYSA-N Erucic acid Natural products CCCCCCC=CCCCCCCCCCCCC(O)=O URXZXNYJPAJJOQ-UHFFFAOYSA-N 0.000 claims description 28
- DPUOLQHDNGRHBS-KTKRTIGZSA-N erucic acid Chemical compound CCCCCCCC\C=C/CCCCCCCCCCCC(O)=O DPUOLQHDNGRHBS-KTKRTIGZSA-N 0.000 claims description 28
- 244000075850 Avena orientalis Species 0.000 claims description 24
- 235000007319 Avena orientalis Nutrition 0.000 claims description 24
- 239000003921 oil Substances 0.000 claims description 23
- 235000019198 oils Nutrition 0.000 claims description 23
- CRDAMVZIKSXKFV-FBXUGWQNSA-N (2-cis,6-cis)-farnesol Chemical compound CC(C)=CCC\C(C)=C/CC\C(C)=C/CO CRDAMVZIKSXKFV-FBXUGWQNSA-N 0.000 claims description 19
- 239000000260 (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol Substances 0.000 claims description 19
- 229940043259 farnesol Drugs 0.000 claims description 19
- 229930002886 farnesol Natural products 0.000 claims description 19
- CRDAMVZIKSXKFV-UHFFFAOYSA-N trans-Farnesol Natural products CC(C)=CCCC(C)=CCCC(C)=CCO CRDAMVZIKSXKFV-UHFFFAOYSA-N 0.000 claims description 19
- WTVHAMTYZJGJLJ-UHFFFAOYSA-N (+)-(4S,8R)-8-epi-beta-bisabolol Natural products CC(C)=CCCC(C)C1(O)CCC(C)=CC1 WTVHAMTYZJGJLJ-UHFFFAOYSA-N 0.000 claims description 18
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims description 18
- ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 claims description 18
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims description 18
- 229940036350 bisabolol Drugs 0.000 claims description 18
- HHGZABIIYIWLGA-UHFFFAOYSA-N bisabolol Natural products CC1CCC(C(C)(O)CCC=C(C)C)CC1 HHGZABIIYIWLGA-UHFFFAOYSA-N 0.000 claims description 18
- 229940042585 tocopherol acetate Drugs 0.000 claims description 17
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 14
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 6
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 6
- 229930003268 Vitamin C Natural products 0.000 claims description 6
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims description 6
- 235000019154 vitamin C Nutrition 0.000 claims description 6
- 239000011718 vitamin C Substances 0.000 claims description 6
- 229960003966 nicotinamide Drugs 0.000 claims description 5
- 235000005152 nicotinamide Nutrition 0.000 claims description 5
- 239000011570 nicotinamide Substances 0.000 claims description 5
- 229940064064 purslane extract Drugs 0.000 claims description 5
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 claims description 4
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 claims description 4
- 235000013793 astaxanthin Nutrition 0.000 claims description 4
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 claims description 4
- 229940022405 astaxanthin Drugs 0.000 claims description 4
- 239000001168 astaxanthin Substances 0.000 claims description 4
- 229940114124 ferulic acid Drugs 0.000 claims description 4
- KSEBMYQBYZTDHS-HWKANZROSA-N ferulic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-N 0.000 claims description 4
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 claims description 4
- 235000001785 ferulic acid Nutrition 0.000 claims description 4
- 239000007934 lip balm Substances 0.000 claims description 4
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 claims description 4
- AJBZENLMTKDAEK-UHFFFAOYSA-N 3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-4,9-diol Chemical compound CC12CCC(O)C(C)(C)C1CCC(C1(C)CC3O)(C)C2CCC1C1C3(C)CCC1C(=C)C AJBZENLMTKDAEK-UHFFFAOYSA-N 0.000 claims description 3
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims description 3
- 235000003880 Calendula Nutrition 0.000 claims description 3
- 240000001432 Calendula officinalis Species 0.000 claims description 3
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 3
- BIVBRWYINDPWKA-VLQRKCJKSA-L Glycyrrhizinate dipotassium Chemical compound [K+].[K+].O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@H]1CC[C@]2(C)[C@H]3C(=O)C=C4[C@@H]5C[C@](C)(CC[C@@]5(CC[C@@]4(C)[C@]3(C)CC[C@H]2C1(C)C)C)C(O)=O)C([O-])=O)[C@@H]1O[C@H](C([O-])=O)[C@@H](O)[C@H](O)[C@H]1O BIVBRWYINDPWKA-VLQRKCJKSA-L 0.000 claims description 3
- 241000208680 Hamamelis mollis Species 0.000 claims description 3
- 240000007817 Olea europaea Species 0.000 claims description 3
- 229930003571 Vitamin B5 Natural products 0.000 claims description 3
- 229960000458 allantoin Drugs 0.000 claims description 3
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 claims description 3
- 229960002079 calcium pantothenate Drugs 0.000 claims description 3
- 229940059958 centella asiatica extract Drugs 0.000 claims description 3
- 235000019480 chamomile oil Nutrition 0.000 claims description 3
- 239000010628 chamomile oil Substances 0.000 claims description 3
- 229940101029 dipotassium glycyrrhizinate Drugs 0.000 claims description 3
- -1 olive leaf extract Substances 0.000 claims description 3
- 235000009492 vitamin B5 Nutrition 0.000 claims description 3
- 239000011675 vitamin B5 Substances 0.000 claims description 3
- 229940118846 witch hazel Drugs 0.000 claims description 3
- 229940069521 aloe extract Drugs 0.000 claims description 2
- 235000013399 edible fruits Nutrition 0.000 claims description 2
- 229940114496 olive leaf extract Drugs 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 16
- 208000007287 cheilitis Diseases 0.000 abstract description 8
- 206010067484 Adverse reaction Diseases 0.000 abstract description 6
- 230000006838 adverse reaction Effects 0.000 abstract description 6
- 230000003020 moisturizing effect Effects 0.000 abstract description 5
- 239000002537 cosmetic Substances 0.000 abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 4
- 229920000832 Cutin Polymers 0.000 abstract description 3
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 description 22
- 210000003491 skin Anatomy 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 7
- 238000000034 method Methods 0.000 description 6
- 206010040844 Skin exfoliation Diseases 0.000 description 5
- 230000035618 desquamation Effects 0.000 description 5
- 208000003251 Pruritus Diseases 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 208000002193 Pain Diseases 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 206010067482 No adverse event Diseases 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 206010013781 dry mouth Diseases 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 210000004877 mucosa Anatomy 0.000 description 2
- 210000001732 sebaceous gland Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
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- 235000002961 Aloe barbadensis Nutrition 0.000 description 1
- 244000146462 Centella asiatica Species 0.000 description 1
- 235000004032 Centella asiatica Nutrition 0.000 description 1
- 235000007866 Chamaemelum nobile Nutrition 0.000 description 1
- 241000208681 Hamamelis virginiana Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010024552 Lip dry Diseases 0.000 description 1
- 244000042664 Matricaria chamomilla Species 0.000 description 1
- 235000007232 Matricaria chamomilla Nutrition 0.000 description 1
- 239000004909 Moisturizer Substances 0.000 description 1
- 241000795633 Olea <sea slug> Species 0.000 description 1
- 235000002725 Olea europaea Nutrition 0.000 description 1
- 206010051246 Photodermatosis Diseases 0.000 description 1
- 206010039509 Scab Diseases 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- JAWMENYCRQKKJY-UHFFFAOYSA-N [3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-ylmethyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl]-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]methanone Chemical compound N1N=NC=2CN(CCC=21)CC1=NOC2(C1)CCN(CC2)C(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F JAWMENYCRQKKJY-UHFFFAOYSA-N 0.000 description 1
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- 235000011399 aloe vera Nutrition 0.000 description 1
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- 239000003963 antioxidant agent Substances 0.000 description 1
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- ZAKOWWREFLAJOT-UHFFFAOYSA-N d-alpha-Tocopheryl acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-UHFFFAOYSA-N 0.000 description 1
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- 239000000194 fatty acid Substances 0.000 description 1
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- 150000004665 fatty acids Chemical class 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- FOYKKGHVWRFIBD-UHFFFAOYSA-N gamma-tocopherol acetate Natural products CC(=O)OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 FOYKKGHVWRFIBD-UHFFFAOYSA-N 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
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- 230000001333 moisturizer Effects 0.000 description 1
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- 238000007254 oxidation reaction Methods 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 150000007965 phenolic acids Chemical class 0.000 description 1
- 230000008845 photoaging Effects 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
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- 238000007619 statistical method Methods 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
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- 230000000475 sunscreen effect Effects 0.000 description 1
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- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/927—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
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- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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Abstract
The invention relates to a composition for lip care, belonging to the technical field of cosmetics. The technical problem solved by the invention is to provide a composition for lip care. The active ingredients of the composition comprise petrolatum, beeswax and canola oil. The composition for lip care can improve the moisturizing and lip moistening effects of the composition for lip care, moisten and nourish the skin of the lips, soften the cutin of the lips, improve the discomfort of the lips caused by dryness and water shortage, treat exfoliative cheilitis and avoid adverse reactions.
Description
Technical Field
The invention relates to a composition for lip care, belonging to the technical field of cosmetics.
Background
Unlike the skin of other parts, the horny layer of the lips is thin and there are no appendages such as sebaceous glands and hair follicles. Because the lips do not have melanocytes, melanin cannot be effectively secreted to resist photoaging; meanwhile, the lips are not provided with sebaceous glands and can not spontaneously secrete sebum to form a protective layer of a sebaceous membrane, so that the water loss speed of the skin of the lips is much higher than that of the skin of the face. The lip mucosa is the only non-cornified mucosa exposed outside the whole body for a long time, and has poor capability of resisting the change of the external environment, so that the lips are easy to crack, peel and even red and swollen due to the reasons of dryness, coldness, ultraviolet rays and the like. Thus, the lips need to be treated, and the most commonly used lip care substance is lipstick.
The lipstick mainly has the functions of providing a barrier for the moisture locked by the two lips, and simultaneously, relieving and repairing the lips and preventing the dryness phenomenon. At present, the main components of lipstick on the market are mostly petrolatum and wax, although the price is low, the use texture is poor, the reaction of allergy, red swelling and dryness can be easily generated on the fragile lip skin, and the original effect of moisturizing and lip moistening can not be achieved, so that the damage can be brought to the lip skin.
With the improvement of living standard and the upgrading of consumption, the requirements of people on lip cosmetic products are improved, the problems of closed moisturizing, cheilitis resistance, lip skin aging resistance and the like also become new requirements, and the development of a brand-new and upgraded lip care composition is urgently needed to meet the upgrading requirements of people.
Disclosure of Invention
The technical problem solved by the invention is to provide a composition for lip care.
The active ingredients of the lip care composition comprise petrolatum, beeswax and canola oil.
In one embodiment of the present invention, the active ingredient of the composition for lip care comprises the following components in parts by weight: 50-80 parts of petrolatum, 2-12 parts of beeswax and 10-30 parts of low erucic acid rapeseed oil.
In a preferred embodiment of the present invention, the active ingredient of the composition for lip care comprises the following components in parts by weight: 50-80 parts of petrolatum, 2-12 parts of beeswax and 10-30 parts of low erucic acid rapeseed oil
In a more preferred embodiment of the present invention, the active ingredient of the composition for lip care comprises the following components in parts by weight: 72.8 parts of petrolatum, 4 parts of beeswax and 23 parts of low erucic acid rapeseed oil.
Further, the active ingredient of the lip care composition of the present invention further comprises at least one of tocopherol acetate, bisabolol, farnesol, oat kernel oil, calendula extract, dipotassium glycyrrhizinate, chamomile oil, allantoin, aloe vera extract, witch hazel extract, purslane extract, centella asiatica extract, niacinamide, vitamin C, olive fruit extract, ferulic acid, vitamin B5, hypecol extract, olive leaf extract, astaxanthin.
In one embodiment of the present invention, the active ingredient of the composition for lip care further comprises the following components in parts by weight: 0.05-1 part of tocopherol acetate, 0.01-0.8 part of bisabolol, 0.001-0.01 part of farnesol and 0.01-0.1 part of oat kernel oil.
In one embodiment of the invention, the active ingredients of the composition for lip care consist of the following components in parts by weight: 50-80 parts of petrolatum, 2-12 parts of beeswax, 10-30 parts of low erucic acid rapeseed oil, 0.05-1 part of tocopherol acetate, 0.01-0.8 part of bisabolol, 0.001-0.01 part of farnesol and 0.01-0.1 part of oat kernel oil.
In a preferred embodiment of the present invention, the active ingredient of the composition for lip care consists of the following components in parts by weight: 60-75 parts of petrolatum, 4-10 parts of beeswax, 20-30 parts of low erucic acid rapeseed oil, 0.1-0.3 part of tocopherol acetate, 0.04-0.2 part of bisabolol, 0.002-0.01 part of farnesol and 0.01-0.05 part of oat kernel oil.
In a more preferred embodiment of the present invention, the active ingredients of the composition for lip care consist of the following components in parts by weight: 72.8 parts of petrolatum, 4 parts of beeswax, 23 parts of low erucic acid rapeseed oil, 0.1 part of tocopherol acetate, 0.048 part of bisabolol, 0.002 part of farnesol and 0.05 part of oat kernel oil.
In some embodiments of the invention, the composition for lip care is a lipstick, lip mask or lip balm.
Compared with the prior art, the invention has the following beneficial effects:
the composition for lip care can improve the moisturizing and lip moistening effects of the composition for lip care, moisten and nourish the skin of the lips, soften the cutin of the lips, improve the discomfort of the lips caused by dryness and water shortage, treat exfoliative cheilitis and avoid adverse reactions.
Detailed Description
The active ingredients of the lip care composition comprise petrolatum, beeswax and canola oil.
The low erucic acid rapeseed oil is rapeseed oil with an erucic acid content of no more than 3 wt% of fatty acid composition. The low erucic acid rapeseed oil has high content of phenolic substances and high total phenolic acid content, and has important functional activities of bacteriostasis, anti-tumor, anti-inflammation, antivirus and the like besides delaying the oxidation of grease. In addition, the composition also contains a certain amount of sterol, vitamin E, etc. The invention discovers that the combination of the low erucic acid rapeseed oil, the petrolatum and the beeswax can play a role in synergy, so that the moisturizing and lip moistening effects of the composition for lip care can be improved, the lip skin is nourished and softened, the cutin of the lips is softened, the discomfort of the lips caused by dryness and water shortage is improved, exfoliative cheilitis can be treated, and no adverse reaction is caused.
Wherein BEESWAX, INCI is BEESWAX, and is available on the market. PETROLATUM, INCI name PETROLATE, CAS number 8009-03-8, CANOLA OIL, INCI name CANOLA OIL, is also commercially available.
In one embodiment of the present invention, the active ingredient of the composition for lip care comprises the following components in parts by weight: 50-80 parts of petrolatum, 2-12 parts of beeswax and 10-30 parts of low erucic acid rapeseed oil.
In a preferred embodiment of the present invention, the active ingredient of the composition for lip care comprises the following components in parts by weight: 50-80 parts of petrolatum, 2-12 parts of beeswax and 10-30 parts of low erucic acid rapeseed oil
In a more preferred embodiment of the present invention, the active ingredient of the composition for lip care comprises the following components in parts by weight: 72.8 parts of petrolatum, 4 parts of beeswax and 23 parts of low erucic acid rapeseed oil.
Further, the active ingredients of the lip care composition of the present invention further comprise TOCOPHERYL ACETATE (INCI name: tocophenyl ACETATE), BISABOLOL (INCI name: bisarol), FARNESOL (INCI name: FARNESOL), oat kernel OIL, CALENDULA EXTRACT (INCI name: CALENDULA OFFICINALIS EXTRACT), DIPOTASSIUM glycyrrhizinate (INCI name: dipate glycoRRhite), chamomile OIL (INCI name: anthobilis FLOWER OIL), ALLANTOIN (INCI name: alloant), ALOE EXTRACT (INCI name: ALOE vera chamomile), WITCH HAZEL EXTRACT (INCI name: HAMAMELIS VIRGINIANA (wiwort dye) EXTRACT), purslane EXTRACT (INCI name: extracellular OLEA, centella asiatica EXTRACT (INCI name: CENTELLA ASIATICA), purslane EXTRACT (INCI name: EXTRACT) (INCI name: purslane EXTRACT) (vitamin C NIACINAMIDE), nicotinamide emulsion EXTRACT (INCI name: ASCORBIC ACID), and vitamin C EXTRACT (vitamin C) (vitamin C NIACINAMIDE), FERULIC ACID (INCI name: FERULIC ACID), vitamin B5, Crithmum MARITIMUM EXTRACT (INCI name: CRTHMUM MARITIUM EXTRACT), folium Canarii albi EXTRACT (INCI name: OLEA EUROPAEA (OLEVE) LEAF EXTRACT), and ASTAXANTHIN (INCI name: ASTAXANTHIN).
The OAT KERNEL OIL provided by the invention is OAT (AVENA SATIVA) KERNEL OIL in the international cosmetic raw material standard Chinese name, and the INCI name of the OAT KERNEL OIL is AVENA SATIVA (OAT) KERNEL OIL.
In one embodiment of the present invention, the active ingredient of the composition for lip care comprises the following components in parts by weight in addition to the above components: 0.05-1 part of tocopherol acetate, 0.01-0.8 part of bisabolol, 0.001-0.01 part of farnesol and 0.01-0.1 part of oat kernel oil.
In one embodiment of the invention, the active ingredients of the composition for lip care consist of the following components in parts by weight: 50-80 parts of petrolatum, 2-12 parts of beeswax, 10-30 parts of low erucic acid rapeseed oil, 0.05-1 part of tocopherol acetate, 0.01-0.8 part of bisabolol, 0.001-0.01 part of farnesol and 0.01-0.1 part of oat kernel oil.
In a preferred embodiment of the present invention, the active ingredient of the composition for lip care consists of the following components in parts by weight: 60-75 parts of petrolatum, 4-10 parts of beeswax, 20-30 parts of low erucic acid rapeseed oil, 0.1-0.3 part of tocopherol acetate, 0.04-0.2 part of bisabolol, 0.002-0.01 part of farnesol and 0.01-0.05 part of oat kernel oil.
In a more preferred embodiment of the present invention, the active ingredients of the composition for lip care consist of the following components in parts by weight: 72.8 parts of petrolatum, 4 parts of beeswax, 23 parts of low erucic acid rapeseed oil, 0.1 part of tocopherol acetate, 0.048 part of bisabolol, 0.002 part of farnesol and 0.05 part of oat kernel oil.
In addition to the above active ingredients, the lip care composition of the present invention may further comprise adjuvants which do not affect the effect of the composition, such as colorants, antioxidants, moisturizers, preservatives, emulsion stabilizers, skin conditioners, antibacterial agents, softeners, physical sunscreens, and the like.
In some embodiments of the invention, the composition for lip care is a lipstick, lip mask or lip balm. It can be prepared into lipstick, lip mask or lip balm by conventional method in the art.
The following examples are provided to further illustrate the embodiments of the present invention and are not intended to limit the scope of the present invention.
Example 1
The composition for lip care comprises the following components in parts by weight: 70 parts of petrolatum, 4 parts of beeswax and 26 parts of low erucic acid rapeseed oil.
Example 2
The composition for lip care comprises the following components in parts by weight: 70 parts of petrolatum, 6 parts of beeswax and 24 parts of low erucic acid rapeseed oil.
Example 3
The composition for lip care comprises the following components in parts by weight: 65 parts of petrolatum, 5 parts of beeswax and 30 parts of low erucic acid rapeseed oil.
Example 4
The composition for lip care comprises the following components in parts by weight: 72.8 parts of petrolatum, 4 parts of beeswax, 23 parts of low erucic acid rapeseed oil, 0.1 part of tocopherol acetate, 0.048 part of bisabolol, 0.002 part of farnesol and 0.05 part of oat kernel oil.
Example 5
The composition for lip care comprises the following components in parts by weight: 65 parts of petrolatum, 6 parts of beeswax, 28 parts of low erucic acid rapeseed oil, 0.2 part of tocopherol acetate, 0.1 part of bisabolol, 0.004 part of farnesol and 0.01 part of oat kernel oil.
Example 6
The composition for lip care comprises the following components in parts by weight: 60 parts of petrolatum, 10 parts of beeswax, 29 parts of low erucic acid rapeseed oil, 0.3 part of tocopherol acetate, 0.2 part of bisabolol, 0.01 part of farnesol and 0.02 part of oat kernel oil.
Test example 1
1. Study subjects:
180 patients with exfoliative cheilitis are selected, and the diagnosis is definitely confirmed according to clinical symptoms, so that the diagnosis standard (54 men and 126 women) of exfoliative cheilitis is met, and the age is 15-37 years old. Patients were randomly divided into nine groups, a blank base group (active ingredient was the base excluding canola oil in example 1), regular rapeseed oil group (canola oil was changed to regular rapeseed oil in example 1), canola oil group (active ingredient was only canola oil), composition groups for lip care of examples 1-6, each group being 20. All subjects had the symptoms of repeated dryness, desquamation, exudation, incrustation, pain, swelling of lipstick, and had the habit of licking and biting lips.
There were no statistical differences in sex, age, initial chronic cheilitis status and cheilitis area composition ratio between the two groups of patients (P > 0.05).
2. The treatment method comprises the following steps:
all patients in each group were under the careful guidance of the physician to correct bad habits and clean the lips after meals in the morning, at noon and evening and before sleep.
The product is applied to lips and mouth, and can be administered within 30min without drinking water, eating food, and reducing speech. 2 times per day in the morning and at night, for example, drinking water or after eating, it should be supplemented at any time. Lipstick and lip licking are avoided after each group is used, and the curative effect is evaluated after 2 weeks of continuous use.
3. Evaluation indexes are as follows: and the occurrence condition of adverse reaction of the patient is observed in the medication process.
4. The curative effect standard is as follows: judging according to the clinical symptom score, and respectively classifying the symptoms such as skin damage area, dryness/chapping, scabbing, desquamation, pruritus, pain and the like into (0-3) scores according to the absence, lightness, middle and severity; the congestion and swelling are divided into 0-3 points according to the non-, light-, medium-and severe-degrees. And calculating the curative effect index. And (3) clinical control: after treatment, the symptoms of dry mouth and lips, desquamation, pruritus, swelling, pain and the like of a patient disappear, and the curative effect index is 95% or more; the effect is shown: after treatment, the symptoms of dry mouth and lips, desquamation and the like of the patient are obviously improved, and the curative effect index is 60-94%; the method has the following advantages: the symptoms of dry lips, desquamation and the like are relieved, and the curative effect index is 20 to 59 percent; and (4) invalidation: the clinical symptoms and signs of the patients are not improved or even aggravated after the treatment.
5. Statistical analysis:
the SPSS 22.0 version software is used for treatment, the clinical curative effect, the adverse reaction and the recurrence rate of two groups are all expressed as (n,%), and the difference of P less than 0.05 has statistical significance through X2 test.
6. As a result:
method for comparing clinical curative effects
The clinical efficacy statistics are shown in table 1.
TABLE 1
| Group of | Control (ratio) | Display effect (ratio) | Effective (ratio) | Ineffectiveness (ratio) | Total effective rate |
| Blank matrix group | 2 example (10%) | 3 example (15%) | 5 examples (25%) | 10 cases (50%) | 50.00％ |
| Canola oil | 0 example (0%) | 1 example (5%) | 2 example (10%) | 17 example (85%) | 15％ |
| Common rapeseed oil | 3 example (15%) | 5 examples (25%) | 6 examples (30%) | 6 examples (30%) | 70.00％ |
| Example 1 | 8 cases (40%) | 6 examples (30%) | 4 cases (20%) | 2 example (10%) | 90.00％ |
| Example 2 | 7 examples (35%) | 7 examples (35%) | 4 cases (20%) | 2 example (10%) | 90％ |
| Example 3 | 8 cases (40%) | 4 cases (20%) | 6 examples (30%) | 2 example (10%) | 90％ |
| Example 4 | 9 cases (45%) | 6 examples (30%) | 5 examples (25%) | 0 example (0%) | 100％ |
| Example 5 | 8 cases (40%) | 6 examples (30%) | 4 cases (20%) | 2 example (10%) | 90％ |
| Example 6 | 8 cases (40%) | 6 examples (30%) | 4 cases (20%) | 2 example (10%) | 90％ |
As can be seen, the product of the examples of the invention is superior in efficiency, and the differences are statistically significant (X2 ═ 11.656, P < 0.01)
Do untoward effect
In the process of using the blank matrix group, 1 case of pruritus is found, the incidence rate of adverse reactions is 5%, in the process of using the common rapeseed oil group, 1 case of pruritus is found, the incidence rate of adverse reactions is 5%, and the rest groups have no adverse reactions.
Claims (10)
1. Composition for lip care, characterized in that its active ingredients comprise petrolatum, beeswax and canola oil.
2. The composition for lip care according to claim 1, wherein the active ingredients comprise the following components in parts by weight: 50-80 parts of petrolatum, 2-12 parts of beeswax and 10-30 parts of low erucic acid rapeseed oil.
3. The composition for lip care according to claim 2, characterized in that its active ingredients comprise the following components in parts by weight: 60-75 parts of petrolatum, 4-10 parts of beeswax and 20-30 parts of low erucic acid rapeseed oil.
4. The composition for lip care according to claim 2, characterized in that its active ingredients comprise the following components in parts by weight: 72.8 parts of petrolatum, 4 parts of beeswax and 23 parts of low erucic acid rapeseed oil.
5. The composition for lip care according to claim 1, characterized in that: the active ingredients further comprise at least one of tocopherol acetate, bisabolol, farnesol, oat kernel oil, calendula extract, dipotassium glycyrrhizinate, chamomile oil, allantoin, aloe extract, witch hazel extract, purslane extract, centella asiatica extract, niacinamide, vitamin C, olive fruit extract, ferulic acid, vitamin B5, hypecol extract, olive leaf extract, and astaxanthin.
6. The composition for lip care according to claim 2, characterized in that: the active ingredients of the composition also comprise the following components in parts by weight: 0.05-1 part of tocopherol acetate, 0.01-0.8 part of bisabolol, 0.001-0.01 part of farnesol and 0.01-0.1 part of oat kernel oil.
7. The composition for lip care according to claim 6, wherein the active ingredient comprises the following components in parts by weight: 50-80 parts of petrolatum, 2-12 parts of beeswax, 10-30 parts of low erucic acid rapeseed oil, 0.05-1 part of tocopherol acetate, 0.01-0.8 part of bisabolol, 0.001-0.01 part of farnesol and 0.01-0.1 part of oat kernel oil.
8. The composition for lip care according to claim 6, wherein the active ingredient comprises the following components in parts by weight: 60-75 parts of petrolatum, 4-10 parts of beeswax, 20-30 parts of low erucic acid rapeseed oil, 0.1-0.3 part of tocopherol acetate, 0.04-0.2 part of bisabolol, 0.002-0.01 part of farnesol and 0.01-0.05 part of oat kernel oil.
9. The composition for lip care according to claim 6, wherein the active ingredient comprises the following components in parts by weight: 72.8 parts of petrolatum, 4 parts of beeswax, 23 parts of low erucic acid rapeseed oil, 0.1 part of tocopherol acetate, 0.048 part of bisabolol, 0.002 part of farnesol and 0.05 part of oat kernel oil.
10. The composition for lip care according to any one of claims 1 to 9, characterized in that: the composition is lipstick, lip mask or lip balm.
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| CN202111543901.1A CN114177120A (en) | 2021-12-16 | 2021-12-16 | Composition for lip care |
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| CN117838610A (en) * | 2024-03-07 | 2024-04-09 | 天津科技大学 | High-permeability slow-release liposome lipstick for treating plateau cheilitis and preparation method thereof |
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| CN113712846A (en) * | 2020-08-04 | 2021-11-30 | 长沙黛西生物科技有限公司 | Composition and cosmetic composition for skin anti-inflammation and/or moisture retention, lipstick and preparation method thereof |
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| CN113712846A (en) * | 2020-08-04 | 2021-11-30 | 长沙黛西生物科技有限公司 | Composition and cosmetic composition for skin anti-inflammation and/or moisture retention, lipstick and preparation method thereof |
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| CN117838610A (en) * | 2024-03-07 | 2024-04-09 | 天津科技大学 | High-permeability slow-release liposome lipstick for treating plateau cheilitis and preparation method thereof |
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