CN114173561A - Composition of chlorantraniliprole, picoxystrobin and propiconazole - Google Patents

Abstract

The present invention discloses a synergistic combination of chlorantraniliprole, picoxystrobin and propiconazole and compositions thereof, and a method for controlling a wide variety of undesirable pathogenic microorganisms, insect pests and mites of plants, comprising treating the plants/plant parts and the area surrounding the plants. Also disclosed are enhanced efficacy against plant diseases and insect pests as compared to the individual components of the combination. This combination also broadens the therapeutic spectrum and is believed to have a longer residual effect on undesirable pathogenic microorganisms, insect pests and mites. The combination also can increase plant health.

Description

Composition of chlorantraniliprole, picoxystrobin and propiconazole

Technical Field

The invention relates to a combination of chlorantraniliprole (chlorantraniliprole), picoxystrobin (picoxystrobin) and propiconazole (propiconazole) and a composition thereof. In particular, the present invention relates to a composition comprising chlorantraniliprole, picoxystrobin and propiconazole, a process for the preparation of said composition and its use for controlling a wide variety of undesirable phytopathogenic microorganisms, insect pests and mites.

Background

In many important commercial crops, such as agricultural and horticultural crops like rice, pepper, tomatoes, grapes, peas, cotton, fungal infections and insect pests can occur simultaneously, for which the grower either takes control measures alone or simply applies various insecticides and fungicides together. This combination of pesticides may lead to poor efficacy and crop damage due to compatibility problems. Therefore, a premix of the best possible formulation for the combination of insecticide and fungicide will help the grower to combat these important diseases and insects/mites at these crop stages.

A typical problem arising in the field of pest control is to reduce the dosage rate of the active ingredient in order to reduce or avoid adverse environmental or toxicological effects, while still being able to effectively control the disease/pest. Thus, it is desirable to co-apply an effective amount of fungicide and insecticide as a homogeneous composition.

Chlorantraniliprole is an insecticidal compound and belongs to formamido benzamide chemical substances. It was developed by FMC corporation as described in US7,232,836. It is used to control or inhibit a variety of insect pests, including Lepidoptera (Lepidoptera), Coleoptera (Coleoptera), Diptera (Diptera) and Isoptera (Isoptera) insects. It is effective in controlling all stages of development of most target pests. It is classified in group 28 of IRAC mechanisms of action. Chlorantraniliprole is a ryanodine (ryanodine) receptor modulator, and can regulate intracellular Ca²⁺Is released.

Chemically, it is 3-bromo-N- [ 4-chloro-2-methyl-6- [ (methylamino) carbonyl ] phenyl ] -l- (3-chloro-2-pyridinyl) -1H-pyrazole-5-carboxamide, having the following structure:

strobilurin (Strobilurin) derivatives such as picoxystrobin, pyraclostrobin (pyraclosteron), azoxystrobin (azoxystrobin), fluoxastrobin (fluoxastrobin), trifloxystrobin (trifloxystrobin), pyribencarb (pyribencarb) or pyraoxystrobin (pyraoxystrobin) have fungicidal activity. Picoxystrobin is a broad-spectrum fungicide developed by the company jiekang (Zeneca) as described in US5,438,059. It is classified in group 11 of the FRAC mechanism of action, which prevents mitochondrial electron transport, thereby inhibiting the energy supply of the fungus, resulting in the death of the target fungus. Currently, it is used to control various fungal diseases including rust, mold (moulds) and mildew (millews).

Chemically, it is methyl (2E) -3-methoxy-2- {2- [6- (trifluoromethyl) -2-pyridinyloxymethyl ] phenyl } acrylate having the following structure:

propiconazole is a broad-spectrum systemic fungicidal compound, and belongs to triazole chemical substances. It was developed by the Yanssen pharmaceutical company (Janssen Pharmaceutica) as described in US4,079,062. It is classified in group 3 of the FRAC mechanism of action and is useful as a demethylation inhibitor since it binds to 14-alpha demethylase and inhibits 14-alpha demethylase to demethylate the precursor of ergosterol to ergosterol. Currently, it is used to combat diseases caused by:

powdery mildew (Blumeria (old name: Erysiphe) graminis) (powdery mildew (powdery milew)); sclerotinia homoeocarpa (Sclerotinia homoeocarpa) (spot (Dollar spot)), Colletotrichum graminearum (Colletotrichum graminicola), Rhizoctonia solani (Rhizoctonia solani), powdery mildew, Puccinia spp (Puccinia spp.), for example, Puccinia graminis (Puccinia graminis), laetiaria fuciformis (Red leaf scald); limomyces roseipellis (Pink Patch)); smut (Ustilago striatorims) striae (Stripe smut); smut (Ustilago agropyn); large pear spores (Pyricularia grisea); helminthosporium Bipolaris spp and helmhollera spp; pyricularia oryzae (P.oryzae) (Peronospora oryzae (Magnaporthe grisea) of the sexual type, Rhizoctonia solani (Magnaporthe poae) Potophyllum (Gaeumannomyces graminis) (take-all Patch), Microsphaera brasiliensis (Leptosphaera korrae) and Microsphaera naemaria (Leptosphaera namaria namarii), Ophiosphaera graminis (Rhizoctonia graminis), Rhizophora cerealis (Pseudosphaera cerealis) (eye spot), Phyllospora cerealis (Phaseolus sepala), Rhizoctonia cerealis (Rhizoctonia cerealis) (Rhizoctonia solani), Rhizoctonia cerealis (Rhizoctonia solani), Rhizoctonia solani (Rhizoctonia solani) Rust, leaf spot, scab and blight. It also exhibits strong antifeedant properties against the keratin digesting bark beetle (Anthreocerus australis)

Chemically, it is 1- [ [2- (2, 4-dichlorophenyl) -4-propyl-1, 3-dioxolan-2-yl ] methyl ] -1H-1, 2, 4-triazole having the following structure:

several patent applications disclose mixtures of fungicides and insecticides, for example US20120322654, US20080261811, US2008026044, EP2489266 and WO 2011144593. There is no such effective composition that can act on a wide variety of fungi and pests simultaneously.

It has been found that as a solution to the above problems, a combination comprising chlorantraniliprole, picoxystrobin and propiconazole provides an effective composition for controlling a wide variety of undesirable phytopathogenic microorganisms, insect pests and mites.

Disclosure of Invention

In one aspect, the present invention provides a synergistic combination of chlorantraniliprole, picoxystrobin and propiconazole, wherein optionally one or more insecticidal or fungicidal or acaricidal or nematicidal or herbicidal compounds or any combination thereof may be added.

In one aspect, the present invention provides a synergistic combination of chlorantraniliprole, picoxystrobin, and propiconazole to control a wide variety of undesirable phytopathogenic microorganisms, insect pests, and mites.

In another aspect, the present invention provides a synergistic fungicidal and insecticidal combination of chlorantraniliprole, picoxystrobin and propiconazole.

In another embodiment, the present invention provides longer residual control of undesirable phytopathogenic microorganisms, pests and mites treated with a combination of chlorantraniliprole, picoxystrobin and propiconazole.

In one aspect, the present invention provides a synergistic combination of chlorantraniliprole, picoxystrobin and propiconazole to control a wide variety of undesirable phytopathogenic microorganisms, insect pests and mites.

In one aspect, the present invention provides a synergistic composition comprising chlorantraniliprole, picoxystrobin and propiconazole; the composition has fungicidal and/or insecticidal activity.

In another aspect, the present invention provides a method of preparing a composition comprising chlorantraniliprole, picoxystrobin, and propiconazole.

In another aspect, the present invention provides a synergistic composition of chlorantraniliprole, picoxystrobin and propiconazole, wherein the composition is used as a fungicidal and/or insecticidal composition. The composition is selected from a suspending agent (SC), a Wettable Granule (WG), a Wettable Powder (WP), a Water Dispersible Granule (WDG), a water dispersible tablet (WT), an ultra-low volume (ULV) liquid (UL), an ultra-low volume (ULV) suspending agent (SU), a Soluble Powder (SP), a Suspoemulsion (SE), a Granule (GR), an emulsion in water (EG), an emulsion in water (EW), an Emulsifiable Concentrate (EC), a Microemulsion (ME), a dispersible oil suspending agent (OD), a microcapsule suspending agent (CS), a powder (DP) or an Aerosol (AE).

In another aspect, the present invention provides a composition of chlorantraniliprole, picoxystrobin and propiconazole, wherein the active ingredients are chlorantraniliprole, picoxystrobin and propiconazole, and the particle size of the active ingredients is 5 to 60 micrometers, more preferably 5 to 30 micrometers, and most preferably 5 to 10 micrometers.

In another aspect, the present invention provides a composition of chlorantraniliprole, picoxystrobin and propiconazole, wherein the particle size of the active ingredient (d50, measured by laser diffraction after dispersion in an aqueous phase) is from 5 to 40 microns, more preferably from 5 to 30 microns, most preferably from 5 to 10 microns.

In another aspect, the present invention provides a method of improving crop health (plant strengthening) comprising treating the plant with an effective amount of a combination of chlorantraniliprole, picoxystrobin and propiconazole.

The above aspects and other objects will become more apparent in view of the description given below.

Detailed Description

Abbreviations:

AE: aerosol formulation	SG: soluble granules
		CS: microcapsule suspension	SP: soluble powder
DP: powder preparation	SU: ultra-low volume suspending agent
		EC: emulsifiable concentrate	ME: microemulsion preparation
EG: emulsion granule	OD: dispersible oil suspension
		EW: aqueous emulsion	UL: ultra-low volume liquid formulation
e.g.: for example	WDG: water dispersible granule
		GR: granules	WP: wettable powder
SC: suspending agent	WT: water dispersible tablet
		And SE: suspoemulsion formulation

Definition of

The above definitions of terms used in the present disclosure are herein provided for illustrative purposes only and do not limit the scope of the present invention disclosed in the present disclosure in any way.

It is to be understood that the terminology used herein is for the purpose of describing embodiments only and is not intended to be limiting. As used in this specification, the singular forms "a", "an" and "the" include plural referents unless the context clearly dictates otherwise. Thus, for example, reference to "a surfactant" includes one or more such surfactants.

Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Although other methods and materials similar or equivalent to those described herein can be used in the practice of the present invention, the preferred materials and methods are described herein.

As used herein, the terms "comprises," "comprising," "includes," "including," "has," "having" or any other variation thereof, are intended to cover a non-exclusive inclusion, subject to any limitation explicitly indicated. For example, a composition or method that includes a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition or method.

As used herein, unless otherwise specified, the terms "composition" or "formulation" are used interchangeably and are intended to include, but are not limited to, compositions or formulations containing a combination of chlorantraniliprole, picoxystrobin, and propiconazole.

As used herein, the terms "additive" or "adjuvant" or "agriculturally acceptable carrier" are used interchangeably to refer to an inert substance commonly used as a diluent to provide stability or to increase the spectrum of activity of a composition or formulation with or without agrochemical activity or direct action against undesirable pathogenic microorganisms, pests and mites.

As used herein, the term "surfactant" refers to a compound that, when dissolved in a liquid, reduces the surface tension of the liquid, reduces the interfacial tension between two liquids, or reduces the surface tension between a liquid and a solid.

As used herein, the term "stabilizer" refers to a substance capable of imparting an ability to resist physical or chemical deterioration or decomposition.

As used herein, the term "defoamer" refers to a chemical additive that reduces and retards foam formation in industrial process liquids, semisolids, or solids. The terms defoamer (defoaming agent) and antifoam (anti-foaming agent) are used interchangeably.

As used herein, the term "thickener" refers to a polymeric material that increases the viscosity of an aqueous solution at low concentrations and helps stabilize the composition.

Unless otherwise indicated,% means weight percent; and weight percent refers to the weight of each component as a percentage of the total weight of the composition.

As used herein, the term "locus" refers to a plant, plant part, plant propagation material (preferably seeds), soil, area, material or environment in which a pest is growing or is likely to grow.

As used herein, the term "plant part" is understood to refer to all above-and below-ground parts and organs of plants, such as shoots, leaves, flowers and roots, examples including leaves, needles (needles), stems (stems), stalks (stalks), flowers, fruit bodies (fruit-bodies), fruits and seeds, and roots, tubers (tubers) and rhizomes (rhizomes). Plant parts also include harvested plants and vegetative and generative propagation material, for example seedlings (seeds), tubers, rhizomes, cuttings (cuttings) and seeds.

As used herein, the term "effective amount" refers to the amount of active in a composition that achieves an observable effect on the growth of a target organism, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise reducing occurrence and activity. The effective amount can vary for the various compositions used in the present invention. The effective amount of the composition will also vary depending on the prevailing conditions such as the desired pesticidal effect and duration, weather, target species, locus, mode of application and the like.

As used herein, the term "chlorantraniliprole" includes chlorantraniliprole or an agrochemically acceptable salt, ester, derivative, or any other modified form of chlorantraniliprole.

As used herein, the term "picoxystrobin" includes picoxystrobin or an agrochemically acceptable salt, ester, derivative thereof or any other modified form of picoxystrobin.

As used herein, the term "propiconazole" includes propiconazole or an agrochemically acceptable salt, ester, derivative or any other modified form of propiconazole.

Accordingly, the present invention provides a synergistic combination of chlorantraniliprole, picoxystrobin and propiconazole, wherein optionally one or more insecticidal or fungicidal or acaricidal or nematicidal or herbicidal compounds or any combination thereof may be added.

In one embodiment, the present invention provides a synergistic combination of chlorantraniliprole, picoxystrobin and propiconazole to control a wide variety of undesirable phytopathogenic microorganisms, insect pests and mites.

In one embodiment, the present invention provides a synergistic fungicidal and insecticidal combination of chlorantraniliprole, picoxystrobin and propiconazole.

In another embodiment, the present invention provides longer residual control of undesirable phytopathogenic microorganisms, pests and mites treated with a combination of chlorantraniliprole, picoxystrobin and propiconazole.

The combined ratio of chlorantraniliprole, picoxystrobin and propiconazole depends on various factors, such as the harmful phytopathogenic microorganisms to be controlled, insect pests and mites, degree of infestation, climatic conditions, soil characteristics and method of application, wherein the ratio of chlorantraniliprole, picoxystrobin and propiconazole is from 1: 10: 20 to 1: 2: 3, more preferably from 1: 5: 10 to 1: 2: 3, most preferably from 1: 3: 5 to 1: 2: 3.

In one embodiment, the present invention provides a synergistic combination of chlorantraniliprole, picoxystrobin and propiconazole for the control of a wide variety of undesirable phytopathogenic microorganisms, insect pests and mites.

In another embodiment, the present invention provides a synergistic composition of chlorantraniliprole, picoxystrobin and propiconazole, wherein the composition is used as a fungicidal and/or insecticidal composition. The composition is selected from a suspending agent (SC), a Wettable Granule (WG), a Wettable Powder (WP), a Water Dispersible Granule (WDG), a water dispersible tablet (WT), an Ultra Low Volume (ULV) liquid (UL), an Ultra Low Volume (ULV) Suspension (SU), a Soluble Powder (SP), a Suspoemulsion (SE), a Granule (GR), an Emulsion Granule (EG), an emulsion in water (EW), an Emulsifiable Concentrate (EC), a Microemulsion (ME), a dispersible oil suspension (OD), a microcapsule suspension (CS), a powder (DP) or an Aerosol (AE).

In a specific embodiment, the present invention provides a Suspension Concentrate (SC) composition of chlorantraniliprole, picoxystrobin, and propiconazole.

In a specific embodiment, the present invention provides a Suspoemulsion (SE) composition of chlorantraniliprole, picoxystrobin, and propiconazole.

In one embodiment, the present invention provides an Emulsifiable Concentrate (EC) composition of chlorantraniliprole, picoxystrobin, and propiconazole.

In a specific embodiment, the present invention provides a Wettable Powder (WP) composition of chlorantraniliprole, picoxystrobin and propiconazole.

In a particular embodiment, the present invention provides a Wettable Granule (WG) composition of chlorantraniliprole, picoxystrobin and propiconazole.

In a specific embodiment, the present invention provides a composition of chlorantraniliprole, picoxystrobin and propiconazole, wherein the particle size of the active ingredients chlorantraniliprole, picoxystrobin and propiconazole is 5 to 60 microns, more preferably 5 to 30 microns, most preferably 5 to 10 microns.

In a particular embodiment, the present invention provides a composition of chlorantraniliprole, picoxystrobin and propiconazole wherein the particle size of the active ingredient (d50, measured by laser diffraction after dispersion in the aqueous phase) is from 5 to 40 microns, more preferably from 5 to 30 microns, most preferably from 5 to 10 microns.

In a specific embodiment, the present invention provides a method for preparing a composition of chlorantraniliprole, picoxystrobin and propiconazole, comprising the steps of:

a) adding chlorantraniliprole, picoxystrobin and propiconazole or acceptable salt thereof,

b) an agrochemically acceptable additive selected from the group consisting of surfactants, carriers and other additives is added uniformly to the mixer,

c) optionally grinding with a mill.

In a specific embodiment, the present invention provides a method for preparing a suspending agent (SC) composition of chlorantraniliprole, picoxystrobin and propiconazole, comprising the steps of:

a) grinding picoxystrobin and chlorantraniliprole with an alkoxy polycarbonate, respectively, to obtain an average particle size of about 10 to 40 microns,

b) adding an agrochemically acceptable additive and a proper amount of water,

c) adding propiconazole to the mixture obtained in steps (a) and (b) to obtain a homogeneous mixture,

d) water was added at ambient temperature and ground to obtain a suspension composition with an average particle size of 5-7 nm.

Step (a) of the process for preparing the Suspension Concentrate (SC) composition comprises obtaining picoxystrobin and chlorantraniliprole having an average particle size of about 10 to 40 microns by milling with alkyl polycarboxylates, respectively.

Step (b) of the process for preparing the Suspension Concentrate (SC) composition comprises adding a mixture of excipients and a suitable amount of water, the amount of water being about 60 to 80%.

Step (c) of the process for preparing a Suspension Concentrate (SC) composition comprises mixing the mixture obtained in step (a), step (b) with propiconazole to obtain a homogeneous mixture.

Step (d) of the process for preparing the Suspension Concentrate (SC) composition comprises adding water at ambient temperature and then cooling the mixture at a temperature of about 15 ℃. The resulting mixture was processed in a colloid mill at 10000rpm for 20 minutes to form a suspension having an average particle diameter of 5-7 nm.

These compositions can be manufactured by any method known in The art, for example, "Pesticide Formulation Guide" (edited by Pesticide Science Society of Japan, The Agricultural Formulation and Application Committee, Japan Plant Protection Association, 1997).

The compositions of the present invention comprise a broader ratio of chlorantraniliprole, picoxystrobin and propiconazole, depending on various factors, such as the type of crop, the undesirable phytopathogenic microorganisms to be controlled, the insect pests and mites, the extent of infestation, the climatic conditions, the nature of the soil and the method of application, wherein the weight ratio of chlorantraniliprole, picoxystrobin and propiconazole is from 1: 10: 20 to 1: 2: 3, more preferably from 1: 5: 10 to 1: 2: 3, most preferably from 1: 3: 5 to 1: 2: 3.

Thus, the present invention further provides a composition for controlling a wide variety of undesirable phytopathogenic microorganisms, insect pests and mites, wherein the weight percentage of chlorantraniliprole is from 0.5% to 10%, the weight percentage of picoxystrobin is from 5% to 30% and the weight percentage of propiconazole is from 8% to 50%. The total content of chlorantraniliprole, picoxystrobin and propiconazole in the composition is generally selected in the range of 15% to 80%, preferably 20% to 60% by weight.

The composition comprises an organic or inorganic carrier material, including agriculturally acceptable additives, selected from solid carriers, liquid carriers, gaseous carriers, surfactants, binders, disintegrants, pH adjusting agents, thickeners, preservatives, anti-caking agents, anti-freezing agents, anti-foaming agents, extenders, stabilizers and/or colorants or combinations thereof. The compositions may, if desired, also comprise one or more auxiliaries customary for crop protection compositions.

The solid carrier is selected from, but not limited to, natural minerals such as quartz, talc, kaolin, pyrophyllite, montmorillonite, attapulgite, bentonite, chalk, zeolite, calcite, sericite, clay, acid clay, diatomaceous earth, fuller's earth, sepiolite, gibbsite, dolomite or pumice; synthetic minerals such as precipitated silica, fumed silica, sodium silicate, alumina, aluminum hydroxide; inorganic salts such as calcium carbonate, ammonium sulfate, sodium sulfate, potassium chloride, organic materials such as urea, solid polyoxyethylene, solid polyoxypropylene, polyethylene, polypropylene, lactose, starch, lignin, cellulose, cottonseed hull, wheat flour, soybean flour, wood flour, walnut shell flour, plant flour, sawdust, coconut shell, corn cob, and tobacco stem. These solid carriers may be used alone or in combination.

The liquid carrier is selected from, but not limited to, water; alcohols such as ethanol, propanol, butanol, n-octanol, isopropanol, ethylene glycol, diethylene glycol, propylene glycol, polyethylene glycol, benzyl alcohol, glycerol; polyhydric alcohol ethers such as ethylene glycol monopropyl ether, diethylene glycol monomethyl ether, dipropylene glycol dimethyl ether; ketones, such as acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone; ethers such as dipropyl ether, dioxane, tetrahydrofuran; aliphatic hydrocarbons such as normal paraffin, isoparaffin, kerosene, mineral oil; aromatic hydrocarbons, such as xylene, toluene, naphthenic hydrocarbons (naphthene), solvent naphtha, solvent C9(solvent C9), solvent C10(solvent C10), solvent C12(solvent C10), solvent o 100, solvent o 150, solvent o 200; chlorinated aliphatic or aromatic hydrocarbons, such as chlorobenzene, vinyl chloride, dichloromethane; esters, such as ethyl acetate, diisopropyl phthalate, dimethyl adipate, methyl oleate, methyl tallate; lactones such as gamma-butyrolactone, gamma-valerolactone, epsilon-caprolactone; amides such as dimethylformamide, N-methylpyrrolidone, N-octylpyrrolidone, N-dimethyldecanamide; nitriles, such as acetonitrile; organic sulfur compounds such as dimethyl sulfoxide; vegetable oils, such as soybean oil, rapeseed oil, and cottonseed oil. These liquid carriers may be used alone or in combination.

The gaseous carrier is selected from, but not limited to, liquefied petroleum gas, air, nitrogen, carbon dioxide or dimethyl ether. These gas carriers may be used alone or in combination.

Surfactants (dispersants, wetting agents, spreading agents, penetration-enhancing, resistance toRain fastness (rain fastness), adjuvants for soil leaching control, etc.) are nonionic or anionic surfactants or combinations of these surfactants. Preferably, one or more than one surfactant is used. The surfactant is selected from, but not limited to, sugar esters such as sorbitan monolaurate, polyoxyethylene sorbitan monolaurate; C1-C30 alkyl carboxylates, C1-C20 hydroxyalkyl carboxylates, carboxylate-containing polymers, aryl carboxylates, alkyl x having 2 to 32 carbon atoms (e.g., aliphatic di-and tri-carboxylates), such as aconitic acid, adipic acid, aspartic acid, citric acid, fumaric acid, galactaric acid, glutamic acid, glutaric acid, ketoglutaric acid (oxoglutanic acid), maleic acid, malic acid, malonic acid, oxalic acid, sebacic acid, succinic acid, tartaric acid; alkyl glycosides, such as decyl glycoside; polyoxyethylene alkyl ethers, such as polyoxyethylene lauryl ether, polyoxyethylene coconut oil fatty alcohol ether; polyoxyethylene alkynyl ethers such as polyoxyethylene 2, 4, 7, 9-tetramethyl-5-decyne-4, 7-diol ether; polyoxyethylene aryl ethers such as polyoxyethylene nonylphenyl ether or polyoxyethylene tris (phenylethyl) phenyl ether (polyoxyyethylene trisstyrylphenyl ether); polyoxyethylene vegetable oil ethers such as polyoxyethylene castor oil or polyoxyethylene hydrogenated castor oil; a vegetable oil ethoxylate; C6-C20 straight and branched alcohol ethoxylates, C6-C20 alcohol propoxylates, C6-C20 propoxylated and ethoxylated alcohols; polyoxyethylene fatty acid esters such as polyoxyethylene monolaurate, polyoxyethylene distearate or polyoxyethylene resinate; polyoxyethylene polyoxypropylene (EO-PO) block copolymers, e.g.

Polyoxyethylene polyoxypropylene alkyl ethers such as polyoxyethylene polyoxypropylene lauryl ether; polyoxyethylene polyoxypropylene aryl ethers such as polyoxyethylene polyoxypropylene styryl phenyl ether; polyoxyethylene alkylamines, such as polyoxyethylene stearylamine; polyoxyethylene fatty amides, such as lauric diethanolamide; a fluorinated surfactant; alkyl sulfates such as decaSodium dialkyl sulfates; sodium alkyl benzene sulfonate, calcium alkyl benzene sulfonate; polyoxyethylene alkyl ether sulfates such as sodium polyoxyethylene lauryl ether sulfate; polyoxyethylene aryl ether sulfates such as sodium polyoxyethylene nonylphenyl ether sulfate or ammonium polyoxyethylene tris (phenylethyl) phenyl ether sulfate (ammonium polyoxyethylenetriphenylphenyl ether sulfate); aryl sulfonates, e.g. calcium benzenesulfonate, calcium dodecylbenzenesulfonate, sodium naphthalenesulfonate polycondensate (sodium salt) (sodium salt)

D-425) or a sodium naphthalenesulfonate formaldehyde polycondensate; a polyarylphenyl ether ammonium sulfate salt; 'alpha' -olefin sulfonate; lauryl sulfosuccinate (laureth sulfosuccinate), laureth-5 sulfosuccinate, ricinoleic acid amide MEA sulfosuccinate (ricinoleic acid amide MEA sulfosuccinate), undeceneamide MEA sulfosuccinate, diisobutyl sulfosuccinate, dioctyl sulfosuccinate, dihexyl sulfosuccinate, dicyclohexyl sulfosuccinate, diisodecyl succinate, diisotridecyl sulfosuccinate, di (2-ethylhexyl) sulfosuccinate, di (2-methylpentyl) sulfosuccinate, dimethyl pentyl sulfosuccinate, di (butylhexyl) sulfosuccinate, diisooctyl sulfosuccinate or their alkali metal salts, sodium lignosulfonate; sodium salts of polycarboxylic acids; n-methyl fatty acid sarcosinate (N-methyl fatty acid sarcosinate); polyoxyethylene alkyl ether phosphate; polyoxyethylene aryl ether phosphates such as polyoxyethylene phenyl ether phosphate; polyoxyethylene alkylphenyl ether phosphate; graft copolymers, such as polymethyl methacrylate-polyethylene glycol graft copolymers. These surfactants may be used alone or in combination.

The binding or bond imparting agent is selected from, but not limited to, polyvinyl alcohol, dextrin, modified dextrin, soluble starch, guar gum, xanthan gum, sucrose, polyvinylpyrrolidone, gum arabic, polyvinyl acetate, sodium polyacrylate, carboxymethyl cellulose or a salt thereof, carboxymethyl cellulose dextrin, bentonite, polyethylene glycol having an average molecular weight of 6,000 to 20,000, polyethylene oxide having an average molecular weight of 100,000 to 5,000,000, natural phospholipids such as cephalin or lecithin. These binders or adhesion imparting agents may be used alone or in combination.

Disintegrants are selected from, but not limited to, sodium tripolyphosphate, metal stearates, cellulose powder, dextrin, methacrylate copolymers, polyvinylpyrrolidone, polyaminocarboxylic acid chelate compounds, styrene sulfonate/isobutylene/maleic anhydride copolymers, starch/polyacrylonitrile graft copolymers, sodium hexametaphosphate, carboxymethylcellulose, sodium polycarbonate (sodium polycarbonate), bentonite. These disintegrants may be used alone or in combination.

The pH adjusting agent is selected from, but not limited to, sodium or potassium carbonate, sodium or potassium bicarbonate, sodium or potassium dihydrogen phosphate, disodium or dipotassium hydrogen phosphate, citric acid, malic acid, and triethanolamine. These pH adjusters may be used alone or in combination.

Thickeners are selected from, but not limited to, polyvinyl alcohol, carboxymethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymers, acrylic acid graft copolymers, starch derivatives, synthetic macromolecules, such as modified cellulose-based polymers, polycarboxylates, montmorillonites, hectorites (hectonites), attapulgite, polysaccharide gums, such as gellan gum, jelutong gum, xanthan gum, guar gum, gum arabic, tragacanth gum, karaya gum, tara gum, carob gum, agar, carrageenan, alginic acid, propylene glycol alginate, alginates (such as sodium, potassium, ammonium or calcium salts), or inorganic fine powders selected from high purity silica, bentonite, white carbon. These thickeners may be used alone or in combination.

The preservative is selected from, but not limited to, formaldehyde and paraformaldehyde, 2-hydroxydiphenyl ether and its salts, 2-mercaptopyridine N-oxide zinc salt (2-zinc sulfoxydine N-oxide), inorganic sulfites and bisulfites, sodium iodate, chlorobutanol, dehydroacetic acid, formic acid, 1, 6-Bis (4-amidino-2-bromophenoxy) -n-hexane and salts thereof, 10-undecenoic acid and salts thereof, 5-amino-1, 3-bis (2-ethylhexyl) -5-methyl-hexahydropyrimidine, 5-bromo-5-nitro-1, 3-dioxane, 2-bromo-2-nitro-1, 3-propanediol, 2, 4-dichlorobenzyl alcohol, potassium sorbate, 4-hydroxybenzoate, dichlorophen, isothiazolines (isothiazoliazolenes), and isothiazolones (e.g., 1, 2-benzisothiazol-3 (2H) -one (E) (R) ())

GXL), 2-methyl-2H-isothiazol-3-one hydrochloride, 5-chloro-2- (4-chlorobenzyl) -3(2H) -isothiazolone, 5-chloro-2-methyl-2H-isothiazol-3-one hydrochloride, 4, 5-dichloro-2-cyclohexyl-4-isothiazolin-3-one, 4, 5-dichloro-2-octyl-2H-isothiazol-3-one, 2-methyl-2H-isothiazol-3-one, and mixtures thereof, 2-methyl-2H-isothiazol-3-one calcium chloride complex, 2-octyl-2H-isothiazol-3-one). These preservatives may be used alone or in combination.

The anticaking agent is selected from, but not limited to, disodium, dipotassium, disodium and dipotassium benzene disulfonates, glycol-based aqueous solvents such as ethylene glycol, diethylene glycol, dipropylene glycol and propylene glycol, precipitated silica, fumed silica, aluminum silicate, magnesium silicate, sodium silicate, calcium silicate, talc, diatomaceous earth (diatomaceous earth), bentonite, calcium carbonate, sodium carbonate, alumina and talc (talcum), cellulose, attapulgite, diatomaceous earth (kieselguhr), silica aerogel, silica xerogel, perlite, talc, vermiculite, sodium aluminosilicate, zirconium oxychloride, starch, sodium or potassium phthalate, calcium phosphate, calcium nitride, aluminum nitride, copper oxide, magnesium carbonate, magnesium nitride, magnesium phosphate, magnesium oxide, magnesium nitrate, magnesium sulfate, magnesium chloride, magnesium oxide, C10-C22 fatty acids (e.g., palmitic acid, sodium or potassium palmitate), calcium carbonate, magnesium sulfate, magnesium carbonate, and magnesium carbonate, and C22 fatty acid, and/C22 fatty acid, and magnesium carbonate, and/C4, Stearic acid and oleic acid), tricalcium phosphate, hydrophobic starch derivatives, powdered cellulose, polyacrylic acid and its sodium salt, and sodium polyalkylnaphthalenesulfonate. These anti-caking agents may be used alone or in combination.

The anti-freeze agent is selected from, but not limited to, urea, glycerol (glycerine), ethylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, 1, 3-propanediol, 1, 2-butanediol, 1, 3-butanediol, 1, 4-pentanediol, 3-methyl-1, 5-pentanediol, 2, 3-dimethyl-2, 3-butanediol, trimethylolpropane, mannitol, sorbitol, glycerol, pentaerythritol, 1, 4-cyclohexanedimethanol, xylenol, bisphenols (e.g., bisphenol A, etc.), propylene glycol (propylene glycol), glycerol (glycerol), diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, triethylene glycol monomethyl ether, butoxyethanol, butanediol monobutyl ether, dipentaerythritol, tripentaerythritol, diglycerol (diglycerol), Triglycerol (triglycerol), tetraglycerol (tetraglycerol), pentaglycerol (pentaglycerol), hexaglycerol (hexaglycerol), heptaglycerol (heptaglycerol), and octaglycerol (octaglycerol). These antifreeze agents may be used alone or in combination.

The defoaming agent is selected from, but not limited to, organosilicon compounds (e.g., polysiloxanes, polydimethylsiloxanes, silicone oils), magnesium stearate, long chain alcohols, fatty acids, salts of fatty acids, and organofluorine compounds. These antifoaming agents may be used alone or in combination.

The extender is selected from, but not limited to, silicone-type surfactants, cellulose powders, dextrins, processed starches (processed starches), polyaminocarboxylic acid chelates (polyaminocarboxylic acid chelate compounds), crosslinked polyvinylpyrrolidones, copolymers of maleic acid and styrene, methacrylic acid, half esters of polyols with dicarboxylic anhydride polymers, water-soluble salts of polystyrene sulfonic acid. These extenders may be used alone or in combination.

Stabilizers are selected from, but not limited to, desiccants such as zeolites, quicklime or magnesia; antioxidants, such as phenols, amines, sulfur or phosphorus; or ultraviolet absorbers such as salicylic acids or benzophenones. These stabilizers may be used alone or in combination.

The colorant is selected from, but not limited to, inorganic pigments such as iron oxide, titanium oxide, or prussian blue; organic dyes, such as alizarin dyes, azo dyes, metal phthalocyanine dyes. These colorants may be used alone or in combination.

When the additive components are added to the compositions of the invention, the carrier content is generally chosen in the range from 5% to 95%, preferably from 20% to 90%, by weight; the content of the surfactant is generally selected from the range of 0.1% to 30%, preferably 0.5% to 10%, and the content of the other additives is generally selected from the range of 0.1% to 50%.

The composition of the present invention may be applied by any one method selected from atomization (atomization), spreading (spraying), dusting (dusting), spraying (spraying), spreading, dipping, irrigation, injection, mixing, sprinkling (water immersion), foaming, dressing (dressing), coating (coating), blasting (blasting), fumigation (smoking), smoking (smoking), smoke (fog), and painting (painting).

In one embodiment, the present invention provides a method of controlling a wide variety of undesirable phytopathogenic microorganisms, insect pests and mites with an effective amount of a combination of chlorantraniliprole, picoxystrobin and propiconazole.

In one embodiment, the present invention provides a method of controlling undesirable phytopathogenic microorganisms with an effective amount of a synergistic combination of chlorantraniliprole, picoxystrobin and propiconazole.

Undesirable pathogenic microorganisms of the present invention are selected from: white rust (Albugo spp.) (white rust) on ornamental plants, vegetables (e.g. white rust (a. candida)) and sunflowers (e.g. salsify white rust (a. tetragopogonis)); vegetables, citrus fruits (Alternaria citrosum), oilseed rape (Alternaria brassicola) or Alternaria brassicae), sugar beet (Alternaria tenuis), fruits, rice, soy beans, potatoes (e.g. Alternaria solani (a.solani) or Alternaria alternata (a.alternata)), tomatoes (e.g. Alternaria solani or Alternaria alternata) and Alternaria on wheat (Alternaria spp.) (Alternaria leaf spot); rhizopus (Aphanomyces spp.) on sugar beets and vegetables; ascochyta spp on cotton, cereals and vegetables, e.g. wheat Ascochyta (a.tritici) on wheat and barley Ascochyta (a.hordei) on barley; helminthosporium Bipolaris spp and helminthosporium endocordycep spp, such as Cochliobolus carbonum (Northern leaf blight), for example Southern leaf blight (d. maydis) or Northern leaf blight (Northern leaf blast) on maize, for example Southern leaf blast (Southern leaf blast) on maize, or maize-derived helminthosporium (b. zea), for example Northern leaf blast (spot blast) on cereals, and also helminthosporium B. oryzae on rice, turf and oats, for example; powdery mildew (powdery mildew) of Blumeria (old name: Erysiphe) graminis on cereals (e.g. wheat or barley); fruits and berries (e.g. strawberry), vegetables (e.g. lettuce, carrot, root celery (celery) and cabbage), rape, flowers, grapevine, forest plants and Botrytis cinerea (Botrytis cinerea) on wheat (sexually: Botrytis fulva); bremia lactucae (Bremia lactucae) on lettuce (downy mildew); the genus Ceratophys (synonym Ceratophys) on broad-leaved trees and evergreen trees (the synonym Ophiospora (Ophiotoma)) (rot or blight), for example, elm blight (C.ulmi) on elms (elm disease in the Netherlands); cercospora spp, on rice and cotton (Cercospora leaf spot), cotton (e.g. gray leaf spot: Cercospora zeae (c. zeae-maydis)), rice, sugar beet (e.g. urospora betanae (c. beticola)), sugarcane, vegetables, coffee, soybean (e.g. botrytis cinerea (c. sojina) or purpurea sojae) and rice, sunflower (e.g. Cercospora leaf spot: Cercospora helianthus (c. heliothi)), peanut (e.g. early leaf spot: Cercospora arachidicola (c. arachidicola)) (Cercospora oxysporum); brevibacillus sp on peanuts (e.g., peanut late leaf spot C. personatum: late leaf spot); tomato (e.g., Cladosporium fulvum (c.fulvum): leaf mold) and Cladosporium spp on cereals (e.g., Cladosporium graminearum (c.herbarum) on wheat (black ear rot), c.caryigenum (pecan scab) on pecan; stemphylium sp on peanut (c. crotalariae: stemphylium black rot); ergot bacteria on cereals (Claviceps purpurea) (ergot disease); maize (C.carbonum) cereal (e.g.C.graminearum (C.sativus), anamorph: C.tritici (B.sorokiniana)) and Coccidioides (anamorph: Helminthosporium (Helminthosporium) or Helminthosporium (leaf spot)) on rice (e.g.Coccidioides (C.miyabenus), anamorph: H.oryzae (H.oryzae)); cotton (e.g. Colletotrichum gossypii (c.gossypii)), corn (e.g. Colletotrichum graminearum (c.graminicola), anthracnose stem rot), berries, potatoes (e.g. potato anthracnose (c.coccodes), black spot disease), beans (e.g. bean anthracnose (c.linear multiple disease), citrus fruits (e.g. Colletotrichum oxysporum (c.acutum), Colletotrichum gloeosporioides (c.gloeosporioides)) and soybeans (e.g. soybean anthracnose (c.truncatum) or Colletotrichum spicatum) (Colletotrichum sp.) (sexual: crustaceana pericarpium (gloeophilum)) (anthracnose), corium spp. (corium spp.), e.g. carallum (c.sakamura kokia (c.sakh) on rice, and brassica frutesla sp. (c.sp.) (c., and (3) sexual type: neonectria liriodendri: lindera foot disease) and staphyloma (Cylindrocarpon spp.) (e.g. fruit tree rot or grapevine debilitating disease, sexually: genus rosenbergia (necatria spp.) or new rosenbergia (Neonectria spp.); mucor albopica (teleomorpha: Roselliia) necatrix (root/stem rot) on soybean; chromodiplospora (Diplodia spp.), e.g., chromodiplospora rot in cotton; diaporthe spp, for example, phaseolorum (damping off) on soybean; citrus intercalary seat husk (d.citri) (melanose) on citrus fruits; examples of the bacterial diseases include brown spot, and other bacterial diseases on corn, cereals (such as barley (e.g., barley helminthosporium coeruleum (d.teres), netleaf spot), oats (such as barley helminthosporium coeruleum avenae (d.avenae), leaf spot), and wheat (e.g., d.tritici-reptilis: brown spot), helminthosporium on rice and lawn (synonymous with helminthosporium, sexual type: Pyrenophora), and escopa on grapevine (Esca) (old name of phaeacerespora crazydophora, phaeacetonium aleophorum and/or bocetobacter sphaericus), escapa on grapevine (Esca) (dead of escapa, xeromyces xerophycus), brown spot on grapevine (e.sp.7.a), brown spot, brown rot, brown spot, brown rot, brown rot, brown rot, brown rot, brown Mildew (black mold)); powdery mildew (powdery mildew), on sugar beet (e.beta), on rye (e.graminis), on vegetables (e.g. pea powdery mildew), such as cucurbits (e.g. powdery mildew), on cabbage, sunflower, oilseed rape (e.g. cruciferous powdery mildew), on peas and beans (e.g. powdery mildew); curvularia laterosporus (Eutypa lata) on fruit trees, grapevines and ornamental trees (Curvularia canker or dieback, anamorph: Cytosporina lata, synonym Libertella blacharis); helminthosporium (Exserohilum) (synonym helminthosporium) on corn (e.g. helminthosporium grandiflorum (e.turcicum)); fusarium (Fusarium) (sexual type: Gibberella) (blight, root rot or stem rot) on various plants, such as hard knots (hardlock) of cotton, bolls, Fusarium graminearum (f.graminearum) or Fusarium culmorum (f.culmorum) on cereals (e.g., wheat or barley), Fusarium oxysporum (f.oxysporum) on tomatoes, Fusarium solani (f.solani) on soybeans and Fusarium verticillium (f.verticillium) on corn; gaeumannomyces graminis (take-all patch) on cereals (e.g. wheat or barley) and maize; gibberella spp on cereals (e.g. Gibberella zeae) and rice (e.g. Gibberella gambogic (g.fujikuroi): bakanae); periplex husks on grapevine, pome and other plants (glomeriella cingulata) and cotton grommet husks on cotton (g.gossypii); grain staining complex on rice (Grain staining complex); staphylococcal coccobacillus (Guignardia bidwellii) on grapevine (black rot); globulothrix citricola (signardia citricarpa) on citrus fruits (melasma); rust (rust) on rosaceous plants and juniper plants, such as the pear rust (g. sabinae); helminthosporium (synonym: Helminthosporium, sexually: Courospora) on corn, cereals and rice; camelina rust (hemheiia spp.) such as camelina rust (h. vastatrix) on coffee (coffee leaf rust); isaria fuscoporia (Isariopsis clavispora) (synonym Cladosporium vitas) on grapevine; maize (northern leaf blight) of maize (sabatiella zeae); laetiscaria fuciformis (erythroid disease); limomyces roseipellis (melasma); lumenalella maculatus (Leptosphaeria maculans) on oil crops, lumenalia korrae (Leptosphaeria korraea) and Leptosphaeria namari on orchards; ophiosphaerella herpotricha on bermudagrass; microchaetomium spp on peanuts (e.g., peanut mesochitum (L.crassisca)); ascochyta phaseoloides (synonym phaseolina) on soybeans and cotton (root/stem rot); fusarium nivale (Microdochium (synonym) nivale (Umbelliferae) on cereals (e.g. wheat or barley), Sphaerotheca diffusa (Microphaera diffusa) on soybeans, Mycosphaera citrina (Guignaria citricola) (grease spot) on citrus fruits, Sclerotinia spp (Monilinia spp.) such as Sclerotinia nucleata (M.laxa), Sclerotinia sclerotiorum (M.fructicola) and Sclerotinia funiculorum (M.fructicola) (flower and twig blight (bloom and twig blight), brown rot disease), Mycohalella spp (Mycohalella spp.) on cereals and peanuts such as wheat, citrus, wheat, citrus, wheat, citrus, wheat, citrus, wheat, citrus, and citrus, etc Peronospora spp on oilseed rape (e.g. Peronospora parasitica), onions (e.g. Peronospora destructor), tobacco (p.tabacina) and soybean (e.g. Peronospora northeast (p.manshurica)) (downy mildew); maize Phyllosticta maydis (Phyllosticta maydis) on corn (yellow leaf blight); phakopsora pachyrhizi (Phakopsora pachyrhizi) and Phakopsora manillensis (p.meibomiae) (soybean rust); phialophora spp, for example on grapevines (e.g. tracheiphila and p.tetraspora) and soybeans (e.g. brown rot (p.gregata): stalk rot); phoma nigricans (Phoma lingam) on rape and cabbage (root rot and stem rot) and Phoma saccharina (p. betae) (root rot, leaf spot and damping off) on sugar beet; phoma exigua (ascochyta blight) on peas and beans, Phoma blight (Phoma blight) on cotton, Bell rot (Phoma longissima), Phoma arachidicola (dictyophora) on peanuts (netroplasma); phomopsis spp on sunflower, grapevine (e.g. Phomopsis viticola (p. viticola): stem and leaf spot) and soybean (e.g. stalk rot: p. phaseoli, sexually: Diaporthe phaseolorum); genus Phykopsora, such as rust on cotton, thraustochytrium zeae (physodema maydis) on corn (thraustochytrium brown spot); various plants such as capsicum and cucurbits (e.g. Phytophthora capsici (p.capsici)), soybean (e.g. Phytophthora macrospora (p.megaspora), synonym Phytophthora sojae (p.sojae)), potato and tomato (e.g. Phytophthora infestans (p.infestans): late blight)) and broadleaf trees (e.g. Phytophthora polybotrys (p.ramorum): oak death) and Phytophthora on (Phytophthora spp) on peas and beans (e.g. Phytophthora nicotianae (p.nicotianae): downy mildew) (blight, root rot, leaf rot, fruit rot and rot); plasmodiophora brassica (clubroot) on brassica oleracea, brassica campestris, radish (radish), and other plants; plasmopara spp, such as Plasmopara viticola (p.viticola) (downy mildew) on grapevine and Plasmopara holstein (p.halstedii) on sunflower; the genus (Podosphaera spp.) of wishbone on rosaceous plants, hops, pomes and berries, for example, the wishbone (p.leucotricha) on apples; polymyxa (Polymyxa spp.), viral diseases such as those on cereals such as barley and wheat (Polymyxa graminis) and sugar beet (Polymyxa betanae (p.betae)), and transmitted thereby; pseudocercospora cercospora graminicola wheat-based pythium (pseudocercospora hertricoides) on cereals such as wheat or barley (sigatoka: tapetia yallundae); pseudoperonospora (downy mildew) on various plants, such as Pseudoperonospora cubensis (p. cubensis) on cucurbitaceae plants or Pseudoperonospora humuli (p. humini) on lupulus; pyrophosphaera viticola (Pseudopleionella tracheipila) on grapevine (red fire disease or 'rotbrenner', Anopora: Calycota (Phialophora)); puccinia spp (rust) on various plants, for example, p.dichondrae (dichondra) rust on cereals such as wheat, barley or rye (Puccinia recondita), Puccinia triticina (p.tritici) brown or leaf rust, Puccinia striiformis (p.striiformis) (stripe or yellow rust), Puccinia horbia (p.hordei) (short rust), Puccinia graminis (p.graminis) (stem or black rust) or Puccinia recondita (brown or leaf rust), Puccinia on sugarcane (p.kuehnihii) (yellow rust) and Puccinia on asparagus (p.paraguai); puccinia graminis (p.coronata) (crown rust) and puccinia graminis (p.graminis) (stem rust) on oats, puccinia arachidissima (p.arachididis) (rust) on peanuts; pyrenophora tritici-sinensis (Pyrenophora (anamorph: endophytic fungi) (yellow spot)), Pyrenophora teres (P.feres) (netblot) on wheat, or Pyrenophora avenae (P.avenae) (leaf spot) on oat, Pyricularia (Pyricularia spp.) such as Pyricularia oryzae (P.oryzae) on rice, and Pyricularia grisea (P.oryzae) on lawn and cereals (sexually: Pyricularia oryzae (Magnaporthegrisea), Pyricularia grisea (Pythium blight) on Kentaria, and Pyricularia thaliana (P.grisea) on lawn and cereals, Pyrenophora glauca (P.grisea) on lawn and cereals, Pyrenophora tritici (P.grisea) on lawn and vegetable, such as Pyricularia medica sp. on, rice, maize, wheat, cotton, rape, sunflower, soybean, sugarbeet, timothria and various other plants (such as Pseudoperonospora nivale p. solani) on wheat, and P.nigella sp, physiological leaf spot) and septoria betanae (r. betacola) on sugar beets; rhizoctonia species (Rhizoctonia spp) on cotton, rice, potato, lawn, corn, oilseed rape, potato, sugar beet, vegetables and various other plants, such as Rhizoctonia solani (r.solani) (brown spot) (root/stem rot) on soybean, Rhizoctonia solani (r.solani) (sheath blight) on rice and peanut or Rhizoctonia cerealis (r.cerealis) (Rhizoctonia spring blight)) on wheat or barley; rhizopus stolonifer (black mold, soft rot) on strawberries, carrots, cabbage, grapevines and tomatoes; rhynchophorium secalis (clouding disease (scald)) on barley, rye, and triticale; branch of rice broom (Sarocladium oryzae) and s. attenuatum (sheath rot) on rice; sclerotinia spp (stem rot or southern blight) on vegetables and field crops, such as rape, sunflower (e.g. Sclerotinia sclerotiorum) and soybean (e.g. Sclerotinia rolfsii or Sclerotinia sclerotiorum), Sclerotinia homoeocarpa (Sclerotinia sclerotiorum) on peanuts (septoria canescens), Sclerotinia sclerotiorum (s.minor) (Sclerotinia sclerotiorum), Sclerotinia sclerotiorum (s.sclerotiorum) on potatoes (white mold); sclerotinia sclerotiorum (s.rolfsii) on peanuts; septoria (Septoria spp.) on various plants, such as Septoria sojae (s.glycines) on soybean (brown spot), Septoria tritici (s.tritici) on wheat (Septoria), Septoria avenae (s.avenae) on oat (Septoria), Septoria linum (s.linicola) on linseed (phytophthora lini); grapevine devillicate (Uncinula (synonym Erysiphe)) necator) on grapevine (powdery mildew, anamorph: Vibrio cinerea (Oidium tuckeri)); maize (e.g. chaetomium grandis (s. turcicum), the synonym Helminthosporium grandis (Helminthosporium turcium)) and chaetomium on lawn (bacterial blight); maize (e.g., smut (s. reiliana): head smut), smut (Sphacelotheca spp.) on sorghum and sugarcane; sphaerotheca fuliginea (powdery mildew) on Cucurbitaceae plants; potato powdery scab (Spongospora subcoriana) on potatoes and viral diseases transmitted thereby; sphaerotheca sp on cereals, such as, for example, Sphaerotheca nodorum (S. nodorum) on wheat (Sphaerotheca nodorum, sexual type: Leptosphaeria nodorum (Phaeosphaeria [ synonym Phaeosphaeria ] nodorum)); leaf spot and chloa of septaria on rye; stemphylium spp, such as stemphylium leaf spot on cotton, endophytic chytrium endobioticum (potato cancerous disease) on potatoes; excystia species (Taphrina spp.), such as excystia malformate (t. deformans) on peaches and excystia plum (t. pruni) (plum pockets); rhizopusilla (Thielaviopsis spp.) on tobacco, pome, vegetables, soybean and cotton (black root rot), such as rhizopustula (t. basicola) (the synonym schalata elegans); tilletia spp (bunt) or Tilletia burnetii (bunt) on cereals, such as t.tritici (synonym t.caries, wheat bunt) and t.contrivalas (Tilletia dwarf) on wheat; scleronaria carolina (Typhula incarnata) on barley or wheat (gray snow rot); smut sp, e.g. cryptomela nigricans (u.occulta) on rye, smut ice on wheat (u.agropyn); single-spore rust (Uromyces spp.) (rust) on vegetables such as kidney beans (e.g. puccindiculus verrucosus (u.phaseolitus), synonyms phaseomannitis (u.phaseoli)) and sugar beet (e.g. phaseolana aptata (u.betae)); cereals (e.g., smut (u.nuda) and aleuromyces avellana (u.avaenae)), maize (e.g., maize smut (u.maydis): maize smut) and smut (usellago spp.) on sugarcane (smut), which is a grass smut (u.stiifera) (smut) on lawn-planted grass; apple (e.g., Venturia inaequalis) and Venturia (scab) on pear (scab); and Verticillium spp (blight) on various plants such as fruit and ornamental trees, grapevine, berries, vegetables and field crops, for example Verticillium dahliae (v. dahliae) on strawberries, rape, potatoes and tomatoes.

In a preferred embodiment, the present invention provides a fungicidal or insecticidal combination or composition comprising chlorantraniliprole, picoxystrobin and propiconazole to control undesirable pathogenic microorganisms selected from, but not limited to, powdery mildew, erysiphe necator, anthrax, brown spot, pink spot, redline, red stem rot of cereal (red stalk rot), neck rot, smut, gray leaf spot, melted leaf spot, bark beetle, summer leaf spot, early maturing rice leaf spot, all-rot, dead spring leaf spot, necrotic ringspot, snow mold, fusarium, yellow spot, zoysia, stalactinia graminis, yellow rust, stalked rust, crown rust, brown rust, yellow rust, black smut, black stripe smut, brown rust, yellow rust, brown rust, yellow rust, brown spot, yellow spot, brown spot, yellow spot, brown spot, yellow spot, Leaf blight, rhizoctonia solani, black coal mold, snow mold, and sclerotinia sclerotiorum.

The combinations or compositions of the invention are also suitable for controlling undesirable pathogenic microorganisms which occur in plant parts, in the protection of materials such as wood, paper, paint dispersions, fibres or textiles and in the protection of stored products. The term "protection of materials" is understood to mean the protection of technical non-biological materials (e.g. adhesives, glues, wood, paper and cardboard, textiles, leather, paint dispersions, plastics, cooling lubricants, fibers or fabrics) from the invasion and destruction by undesirable pathogenic microorganisms such as fungi and bacteria. For the protection of wood and other materials, particular attention is paid to the following harmful pathogenic microorganisms: ascomycetes (Ascomycetes) fungi, for example, Rhizoctonia spp (Ophiostomas spp.), Rhizoctonia spp (Ceratocystis spp.), Aureobasidium pullulans (Aureobasidium pullulans), Sclerophoma spp, Chaetomium spp (Chaetomium spp.), Humicola spp (Humicola spp.), Petershell spp (Petriella spp.), Phyllospora spp (Trichoderma spp.); basidiomycetes (Basidiomycetes) fungi, such as, for example, dermospora (coniphora spp.), Coriolus (Coriolus spp.), Mucor (Gloeophyllum spp.), shiitake (Lentinus spp.), Pleurotus (Pleurotus spp.), Porphyra spp.), xeroderma (Serpula spp.) and cheese (Tyromyces spp.), Deuteromycetes (Deuteromycetes) fungi, such as, for example, Aspergillus (Aspergillus spp.), Cladosporium spp.), Penicillium (Penicillium spp.), Streptomyces spp., and Trichoderma spp., for example, Streptomyces spp., Aspergillus spp., and fungi (Zygomycetes spp.), and also for the protection of undesirable fungi such as, for example, Trichoderma spp, in fungi, such as, Trichoderma spp: candida spp and Saccharomyces cerevisiae.

The combinations or compositions of the present invention also provide non-agronomic (other than field crop) applications such as applications on horticultural crops (e.g., greenhouses, nurseries or horticultural plants not growing in the field), residential homes, commercial and industrial structures, turf (e.g., turf farms, rangelands, golf courses, turf fields, sports fields, etc.).

In one embodiment, the present invention provides a method of controlling insect pests and mites using an effective amount of a combination of chlorantraniliprole, picoxystrobin, and propiconazole.

The insect pest or mite is selected from the following orders: moths and butterflies (Lepidoptera)), beetles (Coleoptera)), flies, mosquitos (Diptera), thrips (Thysanoptera), termites (Isoptera), cockroaches (Blattaria-Blattodea), stinkbugs (Hemiptera), crickets, grasshoppers, locusts (Orthoptera), arachnids (Acarina), arachnids (acrina), fleas (siphintera), silverfish, fireflies (Thysanura), dry foot worms (dipopada), wigs (Dermaptera), lice (philippinara), or plant parasites.

In another embodiment of the invention, the insect pests and mites are defined from the following orders: lepidoptera (Lepidoptera) (Lepidoptera)), such as black cutworm (Agrotis ypsilon), yellow cutworm (Agrotis segetum) (cutworm)), cotton leafworm (Alabama argillacea), soybean looper (anticasia gemmatalis), apple silverworm (argyresia contugella), oriental armyworm (autogra gamma), pine looper (bupleurum piniarius), fir leafworm (cacalia murrina), tobacco budworm (carpula reticulata), winter looper (cheimaobia brumata), spruce looper (chlamydia saccharina), western spruce (budworm), southern cabbage caterpillar (ostrinia nubilalis), European looper (ostrinia nubila nubilalis), European looper (ostrinia nubila nubilalis), European looper (ostrinia nubila nubilalis), European looper (ostrinia nubila nubilalis), European looper (ostrinia nubila nubilalis), European looper (ostrinia, ostrinia nubila, ostrinia nubila (ostrinia nubila, ostrinia nubila, ostrinia nubila, ostrinia nubila, ostrinia nubila, ostrinia nubila, etc. and (ostrinia nubila, etc. and ostrinia nubila, etc. and (ostrinia, etc. donia nubila, etc. and stem (ostrinia nubila, etc. donii (stem borer nubila, etc.), etc. donii (stem borer, etc. and (e, etc. donia, etc. of stem (stem borer nubila (e, etc. of stem borer nubila (e, etc.), etc. of stem borer (e, etc. of stem borer nubila, etc. of stem borer (stem borer nubila (e, etc. of stem borer (, Evetria bouliana, Feltia subterranean, Helicoverpa punctiferalis (Galleria mellonella), Grapholitha funebrana (Grapholitha funebrana), Grapholitha molesta (Grapholitha molesta), Heliothis armigera (Heliothis virescens), Heliothis virescens (Tobacco budworm), Heliothis virescens (Heliothis zea), Heliothis virescens (Heliothis virescens), Helicoverpa sinensis (Heliothis undalis), Helicoverpa punctifera (Heliothis virescens), Helicoverpa virescens (Heliothis virescens), Helicoverpa punctifera (Helicoverpa punctifera), Helicoverpa virescens (Helicoverpa punctifera virescens), Helicoverpa punctifera virescens (Helicoverpa punctata (Helicoverpa punctifera), Lyricius (Helicoverpa punctifera), Lyricius (Lyricius), Lyricia punctifera punctata (Lyricola terrestris punctifera), Lysima (Lysima) and Lyricius (Lyricius), Lyricius (Lysima punctifera), Lysima (Lysima) and Lysima (Lysima), Lysima terrestris (Lysima), Lysima (Lysima terrestris), Lysima (Lysima terrestris), Lysima (Lysima), Lysima (Lysima), Lysima (Lysima), Lysima (Lysima) Pilat) and Lysima) Pilat), Lysima (Lysima), Lysima (Lysima terrestris), Lysima (Lysima), Lysima (Lysima), Lysima (Lysima), Lysima terrestris), Lysima (Rotif), Lysima (Rotif (Lysima), Lysima (Rotif (Lysima), Lysima (Rotif (Lysima), Lysima (Rotif (Ro, The plant may be selected from the group consisting of Spodoptera frugiperda (Panolis flammea), Spodoptera litura (Pectinophora gossypiella) (Red Convolvulus (pink bollworm)), Spodoptera litura (Peridroma sauca), Spodoptera litura (Phalera budphala), Potato Grapholitura (Phorimaea operculella), Citrus subterrata (Phyllanthus citrus), Pieris europaea (Pieriis brasiliensis), Pieris brassicae (Pieriis rapae) (cabbage caterpillar (imported cabbagum)), Medicago viridis (Plasmopara scabra), Plutella xylostella (Plutella xylostella), Spodoptera glycines (Psathyriella), Spodoptera litura heterosporum (Spodoptera), Spodoptera litura heterospodoptera (Spodoptera), Spodoptera litura (Spodoptera frugiperda (Spodoptera), Spodoptera litura), Spodoptera frugiperda (Spodoptera), Spodoptera (Spodoptera pallida), Spodoptera (Spodoptera spp), Spodoptera frugiperda (Spodoptera spp), Spodoptera spp (Spodoptera spp), Spodoptera pallida), Spodoptera litura), Spodoptera frugiperda (Spodoptera), Spodoptera (Spodoptera frugiperda (Spodoptera), Spodoptera (Spodoptera) and Spodoptera), Spodoptera frugiperda (Spodoptera) Spodoptera (Spodoptera), Spodoptera (Spodoptera) A (Spodoptera), Spodoptera (Spodoptera), Spodoptera) Spodoptera (Spodoptera), Spodoptera) Spodoptera frugiperda (Spodoptera) Spodoptera frugiperda (Spodoptera), Spodoptera) and Spodoptera frugiperda (Spodoptera), Spodoptera frugiperda (Spodoptera), Spodoptera (Spodoptera frugiperda (Spodoptera) and Spodoptera), Spodoptera frugiperda (Spodoptera), Spodoptera) A (Spodoptera), Spodoptera) Spodoptera, Spodoptera (Spodoptera), Spodoptera frugiperda (Spodoptera), Spodoptera (Spodoptera ) and Spodoptera (Spodoptera), Spodo, Grape leaf rollers (grapevine vironema) (grapevine borer (grapevine berry worm)), Desmia funeralis (grape leaf roller), Heliothis virescens (Helicoverpa zea) (corn earworm (corn earword)), Heliothis gossypii (cotton glover I) (cotton bollworm), Heliothis lutea (Agrotis segetum), Heliothis minor (Agrotis ipsilon), Heliothis striata (Agrotis excoria), Helicoverpa armigera (Mandarius quinquefoil) (tomato hornworm)), Heliothis virescens (European hornworm (apple hornworm)) and Heliothis virescens (walnut hornworm) (apple borer), Heliothis virescens (apple armyworm) (green armyworm (gryphora), Lithophanotheca virescens (European mountain armyworm (corn earworm)), and Pholiota indica) (walnut borer (corn earworm),

beetles (Coleoptera), for example narrow Jidinus (Agrilus siuvatus), straight Strongylostoma (Agriotes lineulatus), dark Strongylostoma (Agriotes obsculus), Amphiococcus solsticis, Analandrus dispar, Paralichthys sinensis (Anthonomus grandis), Arthromus pyrifera (Anthonomus pomorum), Aphtona eupatoria, Athous haemorrhoidis, Cryptophycus bicoloris (Atomaria lineolaris), Blastopodium gracilium (Blastophamus nigra), Blitophycus giganteus (Blastopharia nigra), Blitophycus giganteus, Pirophus fabus (Bruchus rupestris), Piperita sativus (Bruchus pisum), Brucheus solanacearus pinorula (Bruch sativa), Bruchera, Byteus, Dicotivochytea (Cassia japonica), Cyrtymenia indica (Ceratophycus), Cyrtymenia indica, Ceripophycus nigra indica (Ceriporia indica), Pieris indica, Cyrtymenia indica (Cereus solani), Pieris (Cereus chinensis (Ctenofovea), Cyrtymenia indica (C), Cyrtymenia indica (C (C., Tobacco flea beetles (epix hirtipnenis), Eutinobium brasiliensis, bark weevil (Hylobius), bark weevil (Hylobius brauniensis), alfalfa weevil (Hyperba potetica), spruce bark beetle (Ipps typographus), Lema bililea, Lema melanopus, potato leaf beetle (Leptotarsa decemlineata) (Colorado potato beetle), beet beetle (Ligmonius californicus), rice water weevil (Lissophorus oryzae oryzophyllus), Melanotus manii, Japanese beetle (Melothria cauliflora), Japanese beetle (Melothria japonica), Japanese beetle (Phyllodendrophyra), Japanese beetle (Phyllodendrophytylum), Japanese beetle (Phyllodendrocalamus grandis), Japanese beetle (Phyllostachydiothria), Japanese beetle (Phyllophytylodes japonica), Japanese beetle (Phyllodendrophysallow, Phyllodendrobium grandis), Japanese beetle (Phyllostachys nigra), Japanese beetle (Phyllodendrocalamus), Japanese beetle (Phyllostachydiothria), Phyllocha, Phyllostachys nigra (Phyllostachys nigra), Phyllostachys nigra (Phyllostachys nigra, Phyllophora (Phyllophora, Phyllo, Striped root nodule elephant (Sitona Lineatus), cereal elephant (Sitophilus granaria), weevil (Diaprep abbrevates) and plum weevil (Conotrachelus nenophar) (plum curculio),

flies, mosquitoes (Diptera), such as Aedes aegypti (Aedes aegypti), Aedes albopictus (Aedes albopictus), Aedes spinifera (Aedes vexans), Euonymus mexicanus (Anastrephanus ludens), Anopheles quinquefolius (Anopheles maculipennis), Anopheles crucus, Anopheles leucotrichum (Anopheles albomanus), Anopheles gambiae (Anopheles gambiae), Anopheles freudenreichii (Anopheles freomberophycus), Anopheles albus (Anopheles leucotrichus), Anopheles minimus (Anopheles minimus), Anopheles tetraorum (Anopheles dyphyllus), Euonymus praecox (Calyphylla), Euonymus terreus mediterranus (Ceratodes flavus), Chrysomycinia terreus (Chrysomycinia sinensis), Chrysomycinia lutea (Cutina), Chrysomycinia sinensis), Chrysomycinia lutea (Chrysomycinia sinensis), Chrysomycinia illus (Chrysomycinia lutea), Chrysomycinia sinensis), Chrysomycinia lutea (Corynebacterium parva), Chrysomycinia sinensis), Chrysomycinia lutea (Corynebacterium parva), Euonymus (Corynebacterium parva sylvestris (Corynebacterium parva), Euonymus (Corynebacterium parva sylvestris (Corynebacterium parva), Euonymus (C (Corynebacterium parvus (C.D.D.D.D.D.D.D.D.D.D.D.D.D.D.D.D.D.D.D.D.C.D.D.D.D.C.C.D.C.D.D.D.C.D.D.C.A), Euonymus (C.D.D.D.D.D.D.C.D.D.D.C.C.D.D.C.C.D.A), Euonymus (C.D.D.D.C.C.C.D.D.D.C.C.D.D.D.D.C.C.D.D.D.C.A.D.C.C.D.D.C.C.C.C.C.C.C.C.C.C.C.D.D.D.D.D.D.D.D.C.C.D.D.D.D.C.D.D.D.D.D.D.D.D.D.C.C.D.C.C.D.C.C.C.C.C.D.D.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C.C, Culex fatigus (Culex quinquefasciata), Culex tarsalis (Culiseta tarsalis), Culex vein-spikemotes (Culiseta inorganata), coccinella melanogaster (Culiseta melanura), Bactrocera cucurbitae (Dacus cucurbitae), Sarcophaga rugosa (Dacus oleae), Diphylloto brassicae (Dasinesuria brassica), Allis sativa fly (Delica anique), Dinophaga coarcta (Delica coarctata), Drosophila griseus (Dellia brassica), Drosophila hominis (Dermatobia hominis), Drosophila japonica (Drosophila suzukii) (Drosophila ptera (Spodoptera), Drosophila melanogaster (Fabricius), Gennula, Gaoyza, Hygrophyta (Hydracus), Ossis (Hypocrea), Ossis dora pallida (Glyphosatus), Glyphosatus tarcus, Haemophila pallida), Glyphosatus prata, Haemophilus pallida (Glyphosatus), Glyphosatus prata, Glyphosatus oblita (Glyphosatus), Glyphosatus oblita (Glyphosatus), Glyphosatus oblitera pallida (Glyphosatus oblita, Glyphosatus oblitera pallida), Glyphosatus oblita (Glyphosatus oblita, Glyphosatus oblitera pallida), Glyphosatus oblita (Glyphosatus), Glyphosatus oblitera pallida (Glyphosatus), Glyphosatus oblita (Glyphosatus oblita, Glyphosatus), Glyphosatus oblitera pallida), Glyphosatus oblita, Glyphosatus), Glyphosatus oblita (Glyphosatus), Glyphosatus oblita (Glyphosatus oblita, Glyphosatus), Glyphosatus oblita (Glyphosatus), Glyphosatus oblita (Glyphosatus obliquus pallida), Glyphosatus obliquus pallida (Glyphosatus), Glyphosatus obliquus pallida (Glyphosatus), Glyphosatus) and Glyphosatus, Glyphosatus obliquus pallida), Glyphosatus obliquus pallida (Glyphosatus ), Glyphosatus), Glyphosatus, Lucilis, Glyphosatus, Gl, Tetranychus urticae (Liriomyza trifolii), Lucilia caprina, Lucilia cuprina (Lucilia cuprina), Lucilia sericata (Lucilia sericata), Lycoria pecoralis, Mansonia titillanus, Heisea nigricans (Mayetia destructor), Musca domestica (Musca domestica), Musca stablipes (Muscina stablans), Musca ovis ovirina (Oestrus ovis), Opomya florum, Sclerotidae (Oscinella frypris), Pegomya hysocymi, Phorbia anta, Phorbia brassica, Phorbia corartata, Paulophyllus chrysolepis (Phellonitus argentipes), Cochlophia argentifolia (Phomopsis argentifolia), Codium pseudoptera (Psorophora), Musca domestica (Sarcopora), Sarcopora indica (Sarcopora), Sarcopora indica), Sarcopora (Sarcopora), Sarcopora indica), Sarcopora (Sarcopora), Sarcopora indica), Sarcopora (Sarcopora), Sarcopora (Sarcopora indica), Sarcopora (Sarcopora) and Sarcopora (Sarcopora), Sarcopora (Sarcopora), Sarcopora (Sarcopora), Sarcopora (Sarcopora) and Sarcopora (Sarcopora), Sarcopora (Sarcopora), Sarcopora) and Sarcopora (Sarcopora), Sarcopora (Sarcopora) and Sarcopora (Sarcopora), Sarcopora) and Sarcopora (Sarcopora), Sarcopora (Sarcopora) and Sarcopora), Sarcopora (Sarcopora), Sarcopora) and Sarcopora), Sarcopora) and Sarcopora (Sarcopora), Sarcopora (Sarcopora) and Sarcopora (Sarcopora), Sarcopora (Sarcopora) variety (Sarcopora), Sarcopora (Sarcopora), Sarcopora) and Sarcopora), Sarcopora (Sarcopora) and Sarcopora), Sarcopora) and Sarcopora (Sarcopora) and (Sarcopora) including (Sarcopora) variety (Sarcopora), Sarcopora) and Sarcopora (Sarcopora), Sarcopora (Sarcopora), Sarcopora (Sarcopora) and Sarcopora (Sar, The European midge (Tipulaparludosa) and the cherry fruit fly (Rhagoletis cerasi) (cheryfruitfly),

thrips (Thysanoptera), for example, Frankliniella communis (Dichromothripes corbeti), Frankliniella bicolor (Dichromothrips ssp.), Frankliniella tabescens (Frankliniella fusca), Frankliniella occidentalis (Frankliniella occidentalis), Frankliniella orientalis (Frankliniella tritici), Frankliniella citri (Scirothricinus citri), Frankliniella citri (Cistus Thrips), Frankliniella oryzae (Thrips oryzae), Frankliniella palmaris (Thrips palmi), Frankliniella tabescens (Thripula tabaci) and Frankliniella vinifera (Drephonithrips (grape Thrips) are used as raw materials

Termities (isoptera), such as Calotermes flaviolis, Leucotermes flavipes, Heterotomes aureus, Reticulitermes flavipes, Reticulitermes virginica, Reticulitermes virginicus, Reticulitermes lucidus, Termes natalensis and Trastomates formosanus,

cockroaches (Blattaria Blattodea), such as german cockroach (Blattaria germanica), asian cockroach (Blattaria ashianae), american cockroach (Periplaneta americana), japanese cockroach (Periplaneta japonica), brown cockroach (Periplaneta rubra), black chest cockroach (Periplaneta fuliginosa), australia cockroach (Periplaneta australiae), and oriental cockroach (Blatta orientalis);

stinkbug (Hemiptera), for example, Pediculus citri (Diaphoraria citri), Lygus lucorum (Acrosteronum hirae), Eugenia giraldii (Blissus leucopterus), Cyrtopeltis nottus, Euglenopsis lucorum (Dysdercus cingulatus), Dysdercus intermedia, Euonymus alatus (Eurygaster integriceps), Euschistus impiementris, Leptoglomus phyropus, Lygus pratensis, Lygus lucorum (Lygus lineolaris), Lygus pratensis, Oryza sativa (Nezara virula), Piesubaratata, Solea inscriptorum, Phytophus citri, Phytopira rapula citri, Aphis japonica (Aphis viridula, Aphis japonica), Aphis japonica (Aphis viridula, Aphis japonica), Aphis viridia, Aphis japonica, Aphis viridia, Aphis japonica (Aphis japonica), Aphis japonica, Aphis viridia, Aphis japonica, Ap, Cerosipha gossypii, Chaetosporin fragae folii, Cryptomyces ribisis, Dreyfusia nodemanniana, Cryptococcus spruce (Dreyfusia piceae), Dysapphia radicola, Dysaula corticostum pseudolarii, Plantago major (Dysapphia plantaginea), Dysapphia pyrifera (Fabaceae), Phyllomyces fabae (Empoasca fabae), Mycoporia persicae (Hypopterus pruni), Phyllophytes theophylla (Hyperomycosis lacustacea), Phyllophysa (Macrosiphumus avenae), Phyllophyceae (Phyllophyceae), Phyllophyceae (Phyllophyceae), Phyllophysa nilotis macroaphis, Phyllophycus alphysa (Myophila niloticus), Phyllophycus alphycus alvarezii (Phyllophycus alphycus alvaroides), Phyllophycus alphycus alvarezii (Myophilus, Phyllophycus alphycus alvaroides), Phyllophycus alphycus alvaroides, Phyllophycus alphycus alvarius, Phyllophycus alphycus alvaroides, Phyllophycus alphycus alvarum indicus (Myophilus), Phyllophycus alphycus alvarum, Phyllophycus alphycus alnus, Phyllophycus alphycus, Phyllophycus alphycus alvarum, Phyllophycus alphycus, Phyllophycus alphycus alvarum, Phyllophycus alphycus, Phyllophycus alphycus, Phyllophycus, Phoma indica (Myzus, Phoma indica (Myzus), Phyllophycus alphycus, Phoma indica), Phyllophycus alphycus, Phoma indica, Pholiota (Myzus, Phoma indica, Pholiota), Phoma indica, Pholiota (Myophilum, Phoma indica), Pholiota (Myophilum, Pholiota), Phoma indica, Pholiota (Myophilum, Phoma sylvestalis), Phoma sylvestum, Phoma sylvestalis), Pholiota (Myophilum, Phoma sylvestalis), Phoma sylvestalis (Myophilum, Phoma sylvestalis), Phoma sylvestalis (Myophilum, Phoma sylvestalis), Phoma sylvestris (Myzus (Myophilum grandis), Phoma sylvestris (Myophilum, Phoma sylvestris, Sappaaphis well, Schizaphis graminum (Schizaphis graminum), Schizoneura lanuginosa, Aphis gramineus (Sitobion avenae), Trialeurodes vaporariorum (Trialeurodes vaporariorum), Trionyx Citricola (Toxoptera aurantii), Rhizopus viniferus (Viteus viii), Cimex leucovora (Cimex lectularius), Cimex hemipterus (Cimex hemipterus), Reduvius senilis, Triatoma subulifera (Triatoma hunt), Cipholus giganteus (Cicadius virilis) (green leafhoppers), Lycopersicon esculentus (Bacillus cocci cockereus) (potato psyllium (potatophylli)), Arilus Citricola, Potentilla tarkii (Citrus reticulata), Citrus reticulata (citrus reticulata), and Sclercanicola (citrus grandis), and (citrus grandis) (Brookula), and (citrus grandis) (Brookurushigelidium),

termites, honeybees, wasps (wasps), sawflies (hymenoptera), such as for example the species Vespidae (Athalia rosae), Atta cephalospora (Atta cephalolotes), Atta capiguara, Atta cephalospora (Atta cephalolotes), Orthosiphon (Atta laevigata), Atta robusta, Atta sexdens, Texas cutanea (Atta texana), Anthemis (Crematogra spp.), Hoplocpapa minuta, Aptheir (Hoplopapapa testinina), Solenopsis microphylla (Monomorium sonniana), Solenopsis tropis (Solenopsis geminata), Solenopsis sanguinea (Solenopsis punctata), Solenopsis nigra, Solenopsis punctatus (Melicosa), Melanophora pomica (Melanophora), Melanophora pomona punctata (Melanophora pomona), Melanophora pomona (Melanophora, Melanophora officinalis), Melanophora officinalis (Melanophora officinalis), Melanophora officinalis (Melanophora), Melanophora officinalis (Melanophora, Melanophora officinalis (Melanophora, Melanophor, Wasps flaveria (Vespa crabro), Polistes rubiginosa, Florida back ants (Camptousfloridanus) and Argentina ants (Linepithama humile),

cricket species, grasshoppers, locusts (orthoptera), such as crickets (Acheta domestica), Gryllotalpa Gryllotalpa, Locusta migratoria (Lousta migoritia), Melanulus bivittatus, Melanulus ferrugineus (Melanophagus ferrugum), Melanugineus mexicanus (Melanophagus mexicanus), Melanuginella sanguinii (Melanophagus sanguinipes), Locusta migratoria (Melanopsis spruce), Locusta migratoria (Melanotus migratorius), Locusta americana (Schistocaerucus), Locusta multocida (Nomadecopus macrophyllus), Locusta americana (Schistocerica), Locusta (Schistocarinica), Locusta (Phanerochaeus), locustaria (Phanerochaeta), locustaria, Locusta deserticola (Acanthocerana), Locusta trichoderma amatsumaduratus, and Acinetaria (Colostrinia), Locusta,

arachnidae (Arachnoidea), for example arachnids (arahnides) (Acarina), such as Acarina (acarbians) (Acarina), for example Amblyomma (Argasidae), Iridaceae (Ixodidae) and Sarcophytidae (Sarcophytidae), for example Amblyomma americanum (Amblyomma americanum), Orchidactylus variegatus (Amblyomma variegatum), Amblyomma major (Amblyomma americanum), Oryza sativa (Boophilus decoroloatus), Oryza microplus (Boophilus), Dermacentor (Dermacentor luteola), Dermacentor (Dermacentus), Oryza sativa (Amblyomma americanum), Oryza ornithicus (Iridaria), Oryza nilla (Oryza sativa), Oryza ornica (Oryza), Oryza sativa (Iridaria), Oryza ornus), Oryza ornica (Oryza sativa), Oryza (Oryza), Oryza sativa (Oryza), Oryza sativa), Oryza (Oryza), Oryza sativa (Oryza), Oryza (Oryza sativa), Oryza (Oryza sativa) and Oryza (Oryza), Oryza (Oryza sativa), Oryza (Oryza), Oryza sativum (Oryza) or Oryza), Oryza (Oryza) or Oryza, Oryza (Oryza), Oryza sative (Oryza) or Oryza), Oryza sativa), Oryza (Oryza) or Oryza (Oryza) of Oryza, Oryza (Oryza sativa), Oryza (Oryza ) or Oryza (Oryza) or Oryza, Oryza) or Oryza (Oryza, Oryza (Oryza) or Oryza, Oryza (Oryza sative (Oryza) or Oryza, Oryza (Oryza sativa, Oryza) or Oryza, Oryza (Oryza, Oryza (Oryza, Oryza (Oryza) and Oryza, Oryza (Oryza) or Oryza, Oryza (Oryza, Oryza (Oryza, scrapie ovis (Psoroptes ovis), Rhipicephalus sanguineus (Rhipicephalus sanguineus), Rhipicephalus caudatus (Rhipicephalus aperdiculus), Rhipicephalus eversus (Rhipicephalus evertsi), Sarcoptes scabies (Sarcoptes scabies), and gophycidae species (eriophyceae spp.), such as codling rust mite (Aculus schlechlendole), citrus gall mite (phyllocoptera olevora) (citrus rust mite), citrus gall mite (acia fili) (citrus gall mite (citrus bud)) and citrus mite (eriophys filini); tarsonchidae species (Tarsonemidae spp.), such as Phytonemus pallidus and Tarsonemus laterosus (Polyphagata pallidus); a species of the family eustachydidae (tenuipilpidae spp.), such as, for example, brachyporus purpureus (brevipus phoenicis); tetranychidae species (Tetranyhidae spp.), such as Tetranychus cinnabarinus (Tetranychus cinnabarinus), Tetranychus cinnabarinus (Tetranychus kanzawai), Tetranychus pacificus (Tetranychus pacificus), Tetranychus urticae (Tetranychus tetrandrus) and Tetranychus urticae (Tetranychus urticae), Tetranychus ulmi (Panychus ulmi), Panonychus citri (Panonychus citri) (Citrus red mite) and Tetranychus urticae (Oligonchus pratense); araneida (Araneida), such as the black widow spider (Latrodectus macrants) and the brown cricket spider (Loxosceles reclusia),

fleas (fleas) (Siphonaptera), such as Ctenocephalides felis (Ctenocephalides felis), Ctenocephalides canis (Ctenocephalides canis), Xenopsylla cheopis (Xenopsylla cheopis), human fleas (Pulex irrants), Tetranychus penetrans (Tungpenetrrans) and Xenopus australis (Nosopsyllus fasciatus),

silverfish (silverfish), chlamydomonas maculatus (Thysanura), such as silverfish (lepisia saccharana) and chlamydomonas maculatus (Thermobia domestica),

the class of the Chilopoda, such as the Scutigera spp (Scutigera oleoptrata),

millipedes (Diplopoda), such as the genus Narceus,

earwigs (Earwigs) (Dermaptera), such as european Earwigs (forficula auricularia),

lice (1) (Phiriraptera), such as Pediculus humanus (Pediculus humanus capitis), Pediculus humanus (Pediculus humanus murpris), pubic louse (Pthirus pubis), Haliotis bovis (Haematopinus eurystenus), Haliotis suis (Haematopinus suis), Tilapis bovis (Linogatus), Bovilis bovis (Bovicola bovis), Luciola gallinarum (Menopon gallina), Luciola gallinarum (Mencanarthus stramineus) and Tilapis aquatica (Solenopsis callosa),

plant parasitic nematodes: such as root-knot nematodes, peanut root-knot nematodes (Meloidogyne arenaria), chia root-knot nematodes (Meloidogyne chilo di), Meloidogyne pumilus (Meloidogyne exigua), Meloidogyne hapla, Meloidogyne incognita, Meloidogyne javanica and other root-knot nematode species; cyst nematodes (cyst nematodes), potato gold nematodes (Globodera rostochiensis), potato cyst nematodes (Globodera pallida), tobacco cyst nematodes (Globodera tabacum) and other cyst nematode (Globodera) species; heterodera avenae (Heterodera avenae), glycine sojae (Heterodera glycines), glycine betanae (Heterodera schachtii), trefoil cyst nematode (Heterodera trifolii) and other Heterodera (Heterodera) species; seed gall nematodes (Seed gall nematodes), Anguina funesta, wheat grain nematodes (Anguina tritici) and other Ditylenchus (Anguina) species; stem and leaf nematodes, Aphelenchoides besseyi, Aphelenchoides fragiae, Chrysanthemum Aphelenchoides ritzemabosi and other Aphelenchoides species; nematoda (stingnematodas), pratylenchus longicaudatus (Belonolaimus longicaudatus) and other nematoda (Belonolaimus) species; pine nematodes (Pine nematodies), Pine wood nematodes (Bursaphelenchus xylophilus) and other species of Gliocladium spp (Bursaphelenchus); roundworm (Ring nematodes), circumcision (cricole) species, circumcision (cricolella) species, rotifer (cricole) species, cyclostrodia (mesocrynemia) species; stem and bulb nematodes, the species Ditylenchus spp (Ditylenchus destructor), the species Ditylenchus spp (Ditylenchus dipsaci), the species Ditylenchus myceliophiusgugus (Ditylenchus myceliophiumgus) and other species of Stem nematodes (Ditylenchus); trypanosomes (Awl nematodies), trypanosoma (dolichorus) species; helicopterids (spironematodes), dicylongylongylongylon (Helicotylenchus dihystera), pleomorphus (Helicotylenchus multicinctus) and other Helicotylenchus (Helicotylenchus) species, strong Helicotylenchus (Rotylenchus) and other Helicotylenchus (Rotylenchus) species; coleopterans, species of the genus coleoptera (Hemicliophora) and the species of the genus hemistrodia (Hemicconsmoeoides); a species of latent meloidogyne (hirshmaniella); spear nematodes (lancet nemates), columbaria columbiformis (hopolaimus columbius), caenorhabditis capitis (hopolaimus galeatus) and other species of nematodiasis (hopolaimus); pseudorhizoid nematode (false rootknot nematodes), abnormal pearl nematode (Nacobb aberrans) and other species of the genus Phyllanthus (Nacobbus); longneedle nematodes (Needle nematodies), longneedle nematodes (longiderus elengatus) and other longneedle nematode (longiderus) species; (ii) the spicules (pin nematodies), the genus of spicules (parthenochs) species; lesion nematodes (nematodes), brachypodium brachypodioides (Pratylenchus brachyurus), Pratylenchus coffeeensis (Pratylenchus coffeeus), Pratylenchus curvatus, Pratylenchus goodyi, Pratylenchus neogylus (Pratylenchus negenus), Pratylenchus penetrans (Pratylenchus peneratans), strongyloides stichus scripta (Pratylenchus scriber), Pratylenchus vestigius (Pratylenchus vunus vulus), Pratylenchus maydis (Pratylenchus zeae) and other Pratylenchus species; species of Peroideus Cophilus coioides and other species of Peroideus; nematoda (Burrowing nematodas), similar nematoda (Radophyllus similis) and other species of the genus Periploca (Radophyllus); reniform nematodes (reniformed nematodes), Reniform nematodes (Rotylenchus reniformis) and other species of the genus stropharia (Rotylenchus); scutellarian (Scutellonema) species; brachycorrhytides (Stubby root nematodes), primitive ragweed nematodes (Trichodorus privativus) and other Trichodorus species; minor Burstropheid (Paratrichorus minor) and other Burstrophe (Paratrichorus) species; dwarf nematodes (Stunt nematodies), Kletto dwarf nematodes (Tylenochyphus clavytoni), indeterminate dwarf nematodes (Tylenochyphus dubius) and other species of dwarf nematodes (Tylenochyphus) and Mellinius species; citrus nematodes (Citrus nematodies), heminematoda (Tylenchulus semipenetans) and other species of heminematoda (Tylenchulus); sword nematodes (Dagger nematoes), american sword nematodes (xiphonema americanum), standard sword nematodes (xiphonema index), tail-splitting sword nematodes (xiphonema diversicacaudate) and other species of sword nematodes (xiphonema); and other plant parasitic nematode species.

In a preferred embodiment, the present invention provides a fungicidal or insecticidal combination/composition comprising chlorantraniliprole, picoxystrobin and propiconazole for the control of lepidopteran, coleopteran, dipteran, isopteran and acarina insect pests and mites.

The compositions of the present invention for controlling a wide variety of undesirable pathogenic microorganisms, insect pests and mites are advantageous for several purposes, for example:

for addressing a wider range of pests, for example: insecticidal, fungicidal and acaricidal activity;

providing a single application in the form of a homogeneous composition instead of applying the fungicide and insecticide separately;

improved crop health compared to separate application of fungicides and insecticides;

longer residual control time after application of the composition.

In another embodiment, the present invention provides a combination or composition which, when applied to plants, parts of plants, plant propagation material or their locus of growth, has an enhanced effect on undesired pathogenic microorganisms, insect pests and mites compared to the control rates which are possible with the individual compounds and/or control rates suitable for improving the health of plants.

In a further embodiment, the combinations or compositions of the invention are of particular importance for controlling a multitude of undesired pathogenic microorganisms, insect pests and mites on various cultivated plants or plant parts, for example cereals, such as wheat, rye, barley, triticale, oats, rice, mushrooms; sugar beets, such as sugar or fodder beets; fruits, such as pomes, stone fruits or soft fruits, for example apples, apricots, peanuts, pears, pecans, plums (plums), peaches, almonds, cherries, strawberries, raspberries, nectarines, plums (prunes), blackberries or gooseberries; leguminous plants, such as lentils, peas, alfalfa or soybeans; oil plants, such as rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palm, peanuts or soybeans; cucurbitaceae, such as squash, cucumber or melon; fiber plants, such as cotton, flax, hemp or jute; citrus fruits, such as oranges, lemons, grapefruits or mandarins (citrus); vegetables, such as spinach, lettuce, asparagus, cabbage, carrots, onions, tomatoes, potatoes, cucurbits or peppers; lauraceae, such as avocado, cinnamon or camphor; energy and raw material plants, such as corn, soybean, rape, sugar cane or oil palm; corn; tobacco; a nut; coffee; tea; bananas; grapevine (fresh grape and grape juice grapevine); hops; turfgrass; stevia rebaudiana (also known as stevia rebaudiana); natural rubber plants or ornamental and forestry plants, such as flowers, shrubs, broad-leaved trees or evergreens, such as conifers; such as seeds.

In a preferred embodiment, the combinations or compositions of the invention are particularly important for controlling a variety of undesirable pathogenic microorganisms, insect pests and mites in rice, tomato, pepper, soybean and cucumber crops.

In general, the rate of application depends on, for example, the mixing ratio of the active ingredients, the weather conditions, the dosage form, the application time, the application method, the application site, the pests to be controlled and the target crop.

In a method for combating harmful fungi, which depends on the type of compound and the desired effect, the application rate of the mixtures according to the invention is preferably from 5 to 1000g/ha, most preferably from 10 to 750g/ha, in particular from 20 to 500 g/ha.

In the method for controlling pests (insects, acarids or nematodes) depending on the type of compound and the desired effect, the application rate of the mixtures according to the invention is from 20 to 1000g/ha, more preferably from 10g/ha to 750g/ha, in particular from 20 to 500 g/ha.

In one embodiment, the present invention provides a method for improving crop health (phyto-tonic effect) comprising treating a plant with an effective amount of a combination of chlorantraniliprole, picoxystrobin, and propiconazole.

The invention is further illustrated by the following examples. These examples describe possible preferred embodiments for illustrative purposes only, but they do not limit the scope of the invention. These laboratory scale experiments can be scaled up to industrial/commercial scale.

Example 1: preparation of Suspension Concentrate (SC) compositions

Components	％w/w	Function(s)
			Propiconazole	14.4	Al
Picoxystrobin	9.6	Al
			Chlorantraniliprole	4.8	Al
Linear alcohol ethoxylates	8	Wetting agent
			Alkyl polycarboxylates	6	Dispersing agent
Xanthan gum	0.25	Rheology modifier
			Proxel GXL	1	Biocide agent
Silicone oil	1.25	Defoaming agent
			Silica (ppt)	6	Anti-caking agent
Polypropylene glycol	6	Antifreezing agent
			Water (W)	q.s

Example 2: preparation of Suspension Concentrate (SC) compositions

Example 3: preparation of Suspoemulsion (SE) compositions

Components	％w/w	Function(s)
			Propiconazole	14.4	Al
Picoxystrobin	9.6	Al
			Chlorantraniliprole	4.8	Al
EO-PO polymer	5	Dispersing agent
			Linear alcohol ethoxylates	7	Wetting agent
Dioctyl sulfosuccinate	4	Wetting agent
			Alkyl polycarboxylates	6	Dispersing agent
Xanthan gum	0.25	Rheology modifier
			Proxel GXL	1	Biocide agent
Silicone oil	2	Defoaming agent
			Silica (ppt)	8	Anti-caking agent
Polypropylene glycol	6	Antifreezing agent
			Water (W)	q.s

Example 4: preparation of Emulsifiable Concentrate (EC) compositions

Components	％w/w	Function(s)
			Propiconazole	15	Al
Picoxystrobin	10	Al
			Chlorantraniliprole	2	Al
Linear alcohol ethoxylates	8	Emulsifier
			Calcium benzenesulfonate	5	Emulsifier
C9	60	Solvent(s)

Example 5: preparation of Wettable Powder (WP) compositions

Example 6: preparation of Water Dispersible Granule (WDG) composition

Components	％w/w	Function(s)
			Propiconazole	8	Al
Picoxystrobin	18	Al
			Chlorantraniliprole	20	Al
Morwet D425	8	Wetting agent
			Lignosulfonic acid sodium salt	15	Dispersing agent
Silica (ppt)	18	Adsorbent and process for producing the same
			Polyvinyl alcohol	1	Adhesive agent
Clay clay	10	Filler material
			Moisture content	2

Biological examples:

materials and methods

The experiment was carried out at the agricultural research station of PI industries, Inc. of Kashempeth (Telangana), Caliper, Tenon, Toronto, N.C.. A nursery of rice (Oryza sativa L.) was cultivated, and seedlings in the nursery were transplanted at intervals of 20 cm x 15 cm 30 days after sowing. This experiment followed all recommended rice planting criteria. 27 treatments were evaluated in a random complete block design, repeated three times (block size: 5 m x 10 m-50 m). Technical grade pesticides of the insecticides chlorantraniliprole and the fungicides picoxystrobin and propiconazole were purchased and used in different permutations and combinations. Administration of all treatments was completed 30 and 50 days post-transplantation (DAT). Care was taken to avoid the spray solution from drifting to the adjacent experimental block. These applications are accomplished with the aid of a knapsack sprayer which delivers about 500 liters/hectare of spray solution through a flat fan nozzle at a spray pressure of 20-25 psi.

Table 1: treatment details to evaluate the synergistic effect of a combination of chlorantraniliprole, picoxystrobin and propiconazole

All treatments were evaluated for vigor, phytotoxicity and insect/disease control. The vitality description rating is based entirely on visual reflection. For the viability comparison between treatments, the untreated block was considered 100% and the other treatments were visually rated based thereon. Phytotoxicity was recorded on a scale of 0-10 at 10 and 20 days after each application as shown in table 2. All blocks were carefully observed for the phytotoxicity description grades mentioned below.

Table 2: phytotoxicity description rating (0-10)

Chlorantraniliprole is a ryanodine receptor modulator. Chlorantraniliprole activates the ryanodine receptors of insects, stimulating the release of calcium stored inside smooth and striated muscles, resulting in impaired muscle regulation, paralysis and ultimately death of the insect.

Picoxystrobin belongs to strobilurins, inhibits mitochondrial respiration, combines Qo on cytochrome b and blocks electron transfer between cytochrome b and cytochrome c; this disrupts the energy cycle within the fungus by stopping ATP production. Propiconazole acts on fungal pathogens inside the plant during the first haustorium formation stage; it prevents the development of fungi by interfering with the biosynthesis of sterols in the cell membrane, and more precisely it belongs to the DMI-fungicide class (demethylation inhibitors). Therefore, combining all three compounds, each with a different mode of action, is a new approach to addressing both insects and diseases. With this in mind, field experiments were conducted to understand the effect of this combination on pest control and crop yield.

For insect/disease control; plots (hills) of 10 markers (randomly selected) per block were observed from 0 days on application to 10 and 20 days after each application, depending on the disease severity of borer infestation (in the form of a dead heart count), sheath blight and leaf blast. The stem borer infestation was assessed by counting the total tillers and infected tillers. The percentage incidence of heartburn was calculated using the following formula:

the occurrence of sheath blight and leaf blast disease was recorded on a 0-9 scale at 0, 10 and 20 days after each application. In addition, the scoring data was converted to a Percent Disease Index (PDI) using the formula given below.

Finally, when the rice is harvested, recording the grain yield according to the area of the clean block; calculated in tons/hectare and compared between treatments.

Establishment of synergistic action:

surprisingly, this experimental trial demonstrated a synergistic effect of the combination of chlorantraniliprole, picoxystrobin and propiconazole; compared with single application or binary mixture, the composition shows effective control on rice stem borers, banded sclerotial blight and leaf blast.

The expected activity was calculated for the binary combination using the Colby formula:

the expected activity of a given combination of two active compounds (binary composition) can be calculated as follows:

wherein E represents the expected response of two pesticides combined at a specified dose

X-the observed efficacy of the same active ingredient X as the concentration used in the mixture;

y ═ the efficacy observed with the same concentration of active ingredient Y used in the mixture;

when the observed response of the mixture is greater than the expected response (E), the mixture is said to have a synergistic effect.

The expected activity was calculated for the triple combination using the Colby formula:

the expected effect of the combination of the three active ingredients can be calculated according to S.R. Colby ("stabilizing Synergistic and antibacterial Responses of the pharmaceutical compositions", Weeds 1967, 15, 20-22) as follows:

a is the observed efficacy of the same concentration of active ingredient a as used in the mixture;

b-the efficacy observed with the same concentration of active ingredient B as used in the mixture;

c-the efficacy observed with the same concentration of active ingredient C as used in the mixture.

The synergy of the mixture is determined by comparing the observed response (O) of the mixture to an expected or predicted response (E) calculated from the observed response of each individual component administered alone. A mixture is said to have a synergistic effect if the observed response of the mixture is greater than the expected or predicted response (E). Antagonism is obtained if E > O and additivity if E ═ O.

Results

Vigor and phytotoxicity

Visual observation of this combination clearly showed that all three active ingredients were physically compatible and safe for rice crops. Picoxystrobin alone and in combination with propiconazole and chlorantraniliprole showed good plant vigor compared to the control. Vigorous growth was observed in all combination mixtures including picoxystrobin. Grain yield data also supported the vigorous growth observed in each blend treatment (table 3). No symptoms of plant toxicity were observed in any of the treatments applied in combination or alone.

Table 3: grade of vitality

Efficacy of chlorantraniliprole, picoxystrobin and propiconazole on sheath blight and leaf blast

There was no significant difference in the incidence of sheath blight and leaf blast recorded with chlorantraniliprole alone. Binary mixture combinations show good control of these fungal diseases. Surprisingly, the combined mixture of chlorantraniliprole, picoxystrobin and propiconazole recorded the greatest degree of control, unexpectedly in particular control of foliar pest (tables 4 and 5).

Table 4: efficacy of chlorantraniliprole, picoxystrobin and propiconazole on sheath blight

The numbers in parentheses are the percent disease control compared to the control.

Table 5: therapeutic effects of chlorantraniliprole, picoxystrobin and propiconazole on leaf blast

The numbers in parentheses are the percent disease control compared to the control.

Chlorantraniliprole, picoxystrobin and propiconazole control effect on stem borer

The pre-treatment data shows that the difference in the kurtosis counts for each 10 marked mounds in the blocks prepared for the different treatments is nearly identical (table 6). After 20 days of the second application, there was a significant improvement in the kurtosis control in all treatments involving chlorantraniliprole. The untreated block recorded the highest percentage of hearts.

Table 6: efficacy of chlorantraniliprole, picoxystrobin and propiconazole in controlling snout moth's larva

Numbers in parentheses are borer damage control compared to control.

Efficacy of chlorantraniliprole, picoxystrobin and propiconazole on grain yield

The grain yield data showed that treatment No. 25 (chlorantraniliprole @40+ picoxystrobin @80+ propiconazole @120 gai/ha-1: 2: 3) recorded the highest grain yield of 7.89 tons/ha, followed by treatment No. 20 (chlorantraniliprole @25+ picoxystrobin @75+ propiconazole @125 gai/ha-1: 3: 5) and 7.41 tons/ha, indicating synergistic effects respectively (table 7).

Table 7: grain yield

The expected response of the mixture is shown in the table above, followed by the difference between the observed and expected values in parentheses, indicating synergy with the plus (+) sign.

Conclusion

In field conditions, severe crop damage and reduced yield occur when borers, sheath blight and leaf blast occur simultaneously in rice. This occurs many times in many rice-growing countries around the world, as the windows of pest infestation overlap. Surprisingly, a synergistic effect was observed in the combination comprising chlorantraniliprole, picoxystrobin and propiconazole at a ratio of 1: 2: 3 and 1: 3: 5, wherein the pest control effect was significant and a synergistic effect was observed in rice grain yield.

Thus, it will be apparent to those skilled in the art from the foregoing description that many changes and modifications can be made therein without departing from the spirit or scope of the invention as set forth in the description. Accordingly, the scope of the above description is not limited by the above description, but rather the description is to be construed as encompassing all the features and embodiments that may be present in the invention, including all the features and embodiments that would be treated as equivalents thereof by those skilled in the relevant art.

Claims (12)

1. A synergistic combination comprising chlorantraniliprole, picoxystrobin and propiconazole or acceptable salts thereof, optionally with the addition of one or more insecticidal or fungicidal or acaricidal or nematicidal or herbicidal compounds or any combination thereof.

2. The synergistic combination according to claim 1, wherein the ratio of chlorantraniliprole, picoxystrobin and propiconazole is from 1: 10: 20 to 1: 2: 3, more preferably from 1: 5: 10 to 1: 2: 3, most preferably from 1: 3: 5 to 1: 2: 3.

3. A synergistic composition comprising chlorantraniliprole, picoxystrobin and propiconazole or acceptable salts thereof and an agriculturally acceptable additive, optionally with the addition of one or more insecticidal or fungicidal or acaricidal or nematicidal or herbicidal compounds or any combination thereof.

4. The synergistic composition as claimed in claim 3, wherein the ratio of chlorantraniliprole, picoxystrobin and propiconazole is from 1: 10: 20 to 1: 2: 3, more preferably from 1: 5: 10 to 1: 2: 3, most preferably from 1: 3: 5 to 1: 2: 3.

5. The synergistic composition according to claim 3, wherein the particle size of the active ingredients chlorantraniliprole, picoxystrobin and propiconazole is between 5 and 60 microns, more preferably between 5 and 30 microns, most preferably between 5 and 10 microns.

6. The synergistic composition according to claim 3, wherein the particle size of the active ingredient (d50, measured by laser diffraction after dispersion in the aqueous phase) is from 5 to 40 microns, more preferably from 5 to 30 microns, most preferably from 5 to 10 microns.

7. The synergistic composition as claimed in claim 3, wherein the agriculturally acceptable additive is selected from solid carriers, liquid carriers, gaseous carriers, surfactants, binders, disintegrants, pH adjusting agents, thickeners, preservatives, anti-caking agents, anti-freezing agents, anti-foaming agents, extenders, stabilizers and/or colorants or combinations thereof.

8. A method of applying the combination or composition of claim 1 or 3 for the management of an undesirable insect pest or mite or pathogen.

9. The synergistic combination or composition as claimed in claim 1 or 3, wherein the combination or composition additionally comprises one or more compounds selected from insecticides, fungicides, acaricides, nematicides, safeners, herbicides or any combination thereof.

10. The synergistic composition as claimed in claim 3, wherein the synergistic composition is selected from Wettable Powder (WP), Water Dispersible Granules (WDG), water dispersible tablets (WT), Ultra Low Volume (ULV) liquid formulation (UL), Ultra Low Volume (ULV) Suspension (SU), Soluble Powder (SP), soluble Solution (SL), Soluble Granules (SG), Suspoemulsion (SE), Granules (GR), Emulsifiable Granules (EG), aqueous Emulsion (EW), Emulsifiable Concentrate (EC), Microemulsion (ME), oil dispersible suspension (OD), microcapsule suspension (CS), Aerosol (AE) or a mixed formulation of CS and SC (ZC).

11. The synergistic composition as claimed in claim 3, wherein the synergistic composition is a Suspension Concentrate (SC), a Suspoemulsion (SE), an Emulsifiable Concentrate (EC), a Wettable Powder (WP), or a Water Dispersible Granule (WDG).

12. A method of preparing the composition of claim 9, comprising the steps of:

a) adding chlorantraniliprole, picoxystrobin and propiconazole or acceptable salt thereof,

b) an agrochemically acceptable additive selected from the group consisting of surfactants, carriers and other additives is added uniformly to the mixer,

c) optionally grinding with a mill.