WO2011158158A1 - Pesticidal compositions - Google Patents

Pesticidal compositions Download PDF

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Publication number
WO2011158158A1
WO2011158158A1 PCT/IB2011/052537 IB2011052537W WO2011158158A1 WO 2011158158 A1 WO2011158158 A1 WO 2011158158A1 IB 2011052537 W IB2011052537 W IB 2011052537W WO 2011158158 A1 WO2011158158 A1 WO 2011158158A1
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WO
WIPO (PCT)
Prior art keywords
composition
component
compositions
spp
inhibitors
Prior art date
Application number
PCT/IB2011/052537
Other languages
French (fr)
Inventor
Markus Gewehr
Egon Haden
Original Assignee
Basf Se
Basf (China) Company Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se, Basf (China) Company Limited filed Critical Basf Se
Publication of WO2011158158A1 publication Critical patent/WO2011158158A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/12—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, neither directly attached to a ring nor the nitrogen atom being a member of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/22—O-Aryl or S-Aryl esters thereof

Definitions

  • the present invention relates to a composition
  • a composition comprising the following components (1 ) and (2):
  • fungicidal compound (I) selected from inhibitors of phospholipid biosynthesis and cell wall deposition
  • acetylcholinesterase inhibitors selected from carbamates, organopho-mens and triazamate;
  • respiration inhibitors selected from mitochondrial complex I inhibitors and mitochondrial complex II inhibitors
  • insecticides selected from chlorfenapyr, fenbutatin oxide, indoxacarb, metaflumizone, pymetrozine, cyhexatin, diafenthiuron, propargite, ben- clothiaz, bifenazate, cartap, flonicamid, pyridalyl, thiocyclam, cyenopyrafen, dicofol, flupyrazofos, cyflumetofen, amidoflumet, imicyafos, bistrifluron and pyrifluquinazon; in a synergistically effective amount.
  • the invention relates to a method for controlling pests, using the inventive compositions and to the use of component (1 ) and (2) for preparing such compositions, and also to pesticidal compositions comprising such compositions.
  • 'pests' comprises animal pests and phytopathogenic fungi.
  • the present invention provides methods for the control of animal pests (such as insects, acarids and/or nematodes) comprising contacting the ani- mal pest (the insect, acarid or nematode) or their food supply, habitat, breeding grounds or their locus with a pesticidally effective amount of an inventive composition.
  • animal pests such as insects, acarids and/or nematodes
  • the present invention relates to a method of protecting plants from attack or infestation by animal pests (insects, acarids and/or nema- todes) comprising contacting the plant, or the soil or water in which the plant is growing, with a pesticidally effective amount of an inventive composition.
  • the present invention also relates to a method for protecting plant propagation material from harmful insects, arachnids or nematodes comprising contact- ing the plant propagation material with an inventive composition in pesticidally effective amounts.
  • the invention relates to a method for controlling phytopathogenic fungi using the inventive compositions and to the use of the component (1 ) and the component (2) for preparing such compositions, and also to pesticidal compositions compris- ing such compositions.
  • the present invention also comprises a method for protecting plant propagation material from phytopathogenic fungi comprising contacting the plant propagation material with an inventive composition in pesticidally effective amounts.
  • the present invention further relates to plant-protecting active ingredient composi- tions having synergistically enhanced action of improving the health of plants and to a method of applying such inventive compositions to the plants.
  • the compounds of formula (I), (II) as well as their pesticidal action and methods for producing them are generally known.
  • the commercially available compounds may be found in http://www.alanwood.net/pesticides/.
  • they may be found in The Pesticide Manual, 14th Edition, British Crop Protection Council (2006) among other publications.
  • compositions of the present invention which are based on the presence of a compound (I) and a compound (II) are not disclosed therein.
  • inventive compositions show markedly enhanced action against pests compared to the control rates that are possible with the individual compounds when applied to plants, parts of plants, plant propagation materials (preferably seeds), or at their locus of growth.
  • compound (I) and the compound (II) may be applied simultaneously, that is jointly or separately, or may be applied successively. This allows enhanced control of pests, which means animal pests and/or phytopathogenic fungi, compared to the control rates that are possible with the individual compounds (synergistic compositions).
  • the composition comprises as component (1 ) a fungicidal compound (I) selected from inhibitors of phospholipid biosynthesis and cell wall deposition.
  • component (1 ) is selected from benthiavalicarb, dimethomorph, flumorph, iprovalicarb, mandipropamid, pyri- morph, valifenalate, N-(1 -(1 -(4-cyanophenyl)ethanesulfonyl)-but-2-yl) carbamic acid-(4- fluorophenyl) ester and 1 -(4-chloro-phenyl)-1 -(propin-2-yl-oxy)-3-(4-(3,4-dimethoxy- phenyl)-isoxazol-5-yl)-propan-2-one.
  • component (1 ) is se- lected from dimethomorph, flumorph, iprovalicarb, mandipropamid and 1 -(4-chloro- phenyl)-1 -(propin-2-yl-oxy)-3-(4-(3,4-dimethoxy-phenyl)-isoxazol-5-yl)-propan-2-one.
  • component (1 ) is dimethomorph.
  • the composition comprises as component (2) an insecticidal compound (II) selected from the groups (A) to (F):
  • acetylcholinesterase inhibitors selected from carbamates, organophospates and triazamate
  • B sodium channel modulators
  • respiration inhibitors selected from mitochondrial complex I inhibitors and mitochondrial complex II inhibitors.
  • insecticides selected from chlorfenapyr, fenbutatin oxide, indoxacarb,
  • component (2) is selected from from groups (A) to (F), wherein
  • (A) are carbamates, selected from alanycarb, aldicarb, bendiocarb, benfuracarb, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenoxycarb, furathiocarb, methio- carb, methomyl, oxamyl, pirimicarb, propoxur, thiodicarb; organophospates, selected from acephate, azamethiphos, azinphos-methyl, cadusafos, chlorfenvin- phos, chlorpyrifos, dimethoate, diazinon, dichlorvos, dicrotophos disulfoton, ethion, fenitrothion, fenthion, isoxathion, malathion, methamidophos, methi- dathion, methyl-parathion, mevinphos, monocrotophos, oxydemeton-methyl, parathion
  • (C) are insect growth regulators, selected from flufenoxuron, lufenuron, novaluron, buprofezin, teflubenzuron, methoxyfenozide, chlorfluazuron, cyramazin, diflubenzuron, flucycloxuron, hexaflumuron, triflumuron; diofenolan, hexythiazox, etoxazole, clofentezine, halofenozide, tebufenozide, azadirachtin, pyriproxyfen, methoprene, spirodiclofen, spiromesifen, spirotetramat;
  • (D) are macrocyclic lactone insecticides, selected from abamectin, emamectin, mil- bemectin, lepimectin, spinetoram, spinosad;
  • (E) are mitochondrial complex I inhibitors, selecetd from fenazaquin, pyridaben, tolf- enpyrad, flufenerim, tebufenpyrad; and mitochondrial complex II inhibitors, selected from acequinocyl, fluacyprim, hydramethylnon, 2,2-Dimethyl-propionic acid (Z)-2-cyano-1 -(2-methyl-4-trifluoromethyl-thiazol-5-yl)-2-(2-phenyl-thiazol-4-yl)- vinyl ester; and
  • (F) are insecticides, selected from chlorfenapyr, fenbutatin oxide, indoxacarb,
  • metaflumizone metaflumizone, pymetrozine, cyhexatin, diafenthiuron, propargite, benclothiaz, bifenazate, cartap, flonicamid, pyridalyl, thiocyclam, cyenopyrafen, dicofol, flu- pyrazofos, cyflumetofen, amidoflumet, imicyafos, bistrifluron, pyrifluquinazon.
  • the above active ingredient groups, (B), (D) and (F) are defined as follows: are sodium channel modulators, selected from bifenthrin, cypermethrin, zeta- cypermethrin, deltamethrin, esfen-valerate, etofenprox, lambda-cyhalothrin, per- methrin, cyfluthrin, acrinathrin, allethrin, cycloprothrin, cyhalothrin, cyphenothrin, beta-cypermethrin, fenpropathrin, fenvalerate, flucythrinate, imiprothrin, pral- lethrin, pyrethrin I and II, resmethrin, silafluofen, tau-fluvalinate, tetramethrin, tralomethrin, transfluthrin
  • Group (A) is in particular defined as a group consisting of aldicarb, carbofuran, carbosulfan, methiocarb, methomyl, thiodicarb, acephate, chlorpyrifos, dimethoate, malathion, methamidophos, profenofos and terbufos; more particularly aldicarb, carbo- furan, carbosulfan, methiocarb, thiodicarb and dimethoate; even more methiocarb and thiodicarb.
  • Group (B) is, according to a further inventive embodiment, in particular defined as a group consisting of bifenthrin, cypermethrin, alpha-cypermethrin, zeta-cypermethrin, deltamethrin, esfen-valerate, etofenprox, lambda-cyhalothrin, permethrin, tefluthrin, cyfluthrin and betacyfluthrin; more particularly bifenthrin, alpha-cypermethrin, deltamethrin, lambda-cyhalothrin, tefluthrin and betacyfluthrin.
  • Group (B) is, according to another inventive embodiment, in particular defined as a group consisting of bifenthrin, cypermethrin, zeta-cypermethrin, deltamethrin, esfen- valerate, etofenprox, lambda-cyhalothrin, permethrin and cyfluthrin; more particularly bifenthrin, deltamethrin and lambda-cyhalothrin.
  • Group (B) is, according to still another inventive embodiment, in particular defined as a group consisting of bifenthrin, cypermethrin, zeta-cypermethrin, deltamethrin, es- fen-valerate, etofenprox, lambda-cyhalothrin and permethrin; more particularly bifenthrin, deltamethrin and lambda-cyhalothrin.
  • Group (C) is in particular defined as a group consisting of flufenoxuron, lufenuron, novaluron, buprofezin, teflubenzuron and methoxyfenozide; more particularly flufenoxuron and methoxyfenozide.
  • Group (D) is, according to one embodiment, in particular defined as a group consisting of abamectin, emamectin, milbemectin, lepimectin and spinosad; more particularly abamectin, emamectina and spinosad; more specifically abamectin and spinosad.
  • Group (D) is, according to another embodiment, in particular defined as a group consisting of emamectin, milbemectin and lepimectin; specifically emamectin.
  • Group (E) is in particular defined as a group consisting of fenazaquin, tolfenpyrada and hydramethylnon; specifically hydramethylnon.
  • Group (F) is, according to one embodiment, in particular defined as a group consisting of chlorfenapyr, fenbutatin oxide, indoxacarb, metaflumizone, pymetrozine and pyridalyl; more particularly, chlorfenapyr, fenbutatin oxide, indoxacarb, metaflumizone, pymetrozine, specifically chlorfenapyr, metaflumizone and pymetrozine.
  • Group (F) is, according to another embodiment, in particular defined as being a group consisting of chlorfenapyr, fenbutatin oxide, indoxacarb, pymetrozine and pyridalyl; more particularly, chlorfenapyr, fenbutatin oxide, indoxacarb, and pymetrozine; specifically chlorfenapyr and pymetrozine.
  • compositions of the present invention are mixtures, wherein component (1 ) is selected from compounds (l)-1 to (l)-9:
  • component (2) is selected from compounds (ll)-1 to (ll)-29:
  • compositions B1-1 to B1-261 of table B1 wherein each row corresponds to an embodiment of the inventive compositions.
  • Table B1 Binary compositions comprising as component (1) one of compounds (l)-1 to (l)-9 and a component (2) selected from one of compounds (ll)-1 to (ll)-29 component
  • B1-1 (l)-1 (ll)-1 preferably 20:1 to 1:20,
  • B1-2 (l)-1 (ll)-2 preferably 20:1 to 1:20
  • B1-3 (l)-1 (ll)-3 preferably 20:1 to 1:20,
  • B1-4 (l)-1 (ll)-4 preferably 20:1 to 1:20
  • B1-5 (l)-1 (ll)-5 preferably 20:1 to 1:20,
  • B1-6 (l)-1 (ll)-6 preferably 20:1 to 1:20,
  • B1-7 (l)-1 (ll)-7 preferably 20:1 to 1:20,
  • B1-8 (l)-1 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-9 (l)-1 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-10 (l)-1 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-11 (l)-1 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-12 (l)-1 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-13 (l)-1 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-14 (l)-1 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-15 (l)-1 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-16 (l)-1 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-17 (l)-1 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-18 (l)-1 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-19 (l)-1 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-20 (l)-1 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-21 (l)-1 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-22 (l)-1 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-23 (l)-1 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-24 (l)-1 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-25 (l)-1 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-26 (l)-1 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-27 (l)-1 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-28 (l)-1 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-29 (l)-1 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-30 (l)-2 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-31 (l)-2 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-32 (l)-2 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-33 (l)-2 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-34 (l)-2 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-35 (l)-2 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-36 (l)-2 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-37 (l)-2 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-38 (l)-2 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-39 (l)-2 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-41 (l)-2 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-42 (l)-2 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-43 (l)-2 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-44 (l)-2 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-45 (l)-2 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-46 (l)-2 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-47 (l)-2 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-48 (l)-2 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-49 (l)-2 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-50 (l)-2 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-51 (l)-2 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-52 (l)-2 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-53 (l)-2 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-54 (l)-2 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-55 (l)-2 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-56 (l)-2 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-57 (l)-2 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-58 (l)-2 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-59 (l)-3 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-60 (l)-3 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-61 (l)-3 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-62 (l)-3 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-63 (l)-3 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-64 (l)-3 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-65 (l)-3 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-66 (l)-3 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-67 (l)-3 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-68 (l)-3 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-69 (l)-3 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-70 (l)-3 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-71 (l)-3 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-72 (l)-3 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-73 (l)-3 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-74 (l)-3 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-75 (l)-3 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-76 (l)-3 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-77 (l)-3 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-78 (l)-3 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-79 (l)-3 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-80 (l)-3 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-81 (l)-3 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-82 (l)-3 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-83 (l)-3 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-84 (l)-3 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-85 (l)-3 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-86 (l)-3 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-87 (l)-3 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-88 (l)-4 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-89 (l)-4 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-90 (l)-4 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-91 (l)-4 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-92 (l)-4 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-93 (l)-4 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-94 (l)-4 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-95 (l)-4 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-96 (l)-4 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-97 (l)-4 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-98 (l)-4 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-99 (l)-4 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-100 (l)-4 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-101 (l)-4 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-102 (l)-4 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-103 (l)-4 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-104 (l)-4 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-105 (l)-4 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-106 (l)-4 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-107 (l)-4 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-108 (l)-4 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-109 (l)-4 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-110 (l)-4 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-111 (l)-4 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-112 (l)-4 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-113 (l)-4 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-114 (l)-4 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-115 (l)-4 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-116 (l)-4 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-117 (l)-5 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-118 (l)-5 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-119 (l)-5 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-120 (l)-5 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-121 (l)-5 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-122 (l)-5 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-123 (l)-5 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-124 (l)-5 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-125 (l)-5 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-126 (l)-5 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-127 (l)-5 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-128 (l)-5 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-129 (l)-5 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-130 (l)-5 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-131 (l)-5 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-132 (l)-5 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-133 (l)-5 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-134 (l)-5 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-135 (l)-5 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-136 (l)-5 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-137 (l)-5 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-138 (l)-5 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-139 (l)-5 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-140 (l)-5 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-141 (l)-5 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-142 (l)-5 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-143 (l)-5 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-144 (l)-5 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-145 (l)-5 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-146 (l)-6 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-147 (l)-6 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-148 (l)-6 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-149 (l)-6 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-150 (l)-6 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-151 (l)-6 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-152 (l)-6 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-153 (l)-6 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-154 (l)-6 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-155 (l)-6 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-156 (l)-6 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-157 (l)-6 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-158 (l)-6 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-159 (l)-6 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-160 (l)-6 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-161 (l)-6 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-162 (l)-6 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-163 (l)-6 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-164 (l)-6 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-165 (l)-6 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-166 (l)-6 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-167 (l)-6 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-168 (l)-6 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-169 (l)-6 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-170 (l)-6 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-171 (l)-6 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-172 (l)-6 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-173 (l)-6 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-174 (l)-6 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-175 (l)-7 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-176 (l)-7 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-177 (l)-7 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-178 (l)-7 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-179 (l)-7 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-180 (l)-7 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-181 (l)-7 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-182 (l)-7 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-183 (l)-7 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-184 (l)-7 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-185 (l)-7 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-186 (l)-7 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-187 (l)-7 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-188 (l)-7 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-189 (l)-7 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-190 (l)-7 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-191 (l)-7 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-192 (l)-7 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-193 (l)-7 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-194 (l)-7 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-195 (l)-7 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-196 (l)-7 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-197 (l)-7 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-198 (l)-7 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-199 (l)-7 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-200 (l)-7 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-201 (l)-7 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-202 (l)-7 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-203 (l)-7 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-204 (l)-8 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-205 (l)-8 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-206 (l)-8 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-207 (l)-8 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-208 (l)-8 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-209 (l)-8 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-210 (l)-8 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-211 (l)-8 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-212 (l)-8 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-213 (l)-8 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-214 (l)-8 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-215 (l)-8 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B1-216 (l)-8 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-217 (l)-8 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-218 (l)-8 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-219 (l)-8 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-220 (l)-8 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-221 (l)-8 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-222 (l)-8 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-223 (l)-8 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-224 (l)-8 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-225 (l)-8 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-226 (l)-8 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-227 (l)-8 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-228 (l)-8 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B 1-229 (l)-8 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-230 (l)-8 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-231 (l)-8 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-232 (l)-8 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-233 (l)-9 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-234 (l)-9 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-235 (l)-9 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-236 (l)-9 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-237 (l)-9 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-239 (l)-9 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-240 (l)-9 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-241 (l)-9 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B 1-242 (l)-9 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-244 (l)-9 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-245 (l)-9 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-246 (l)-9 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-247 (l)-9 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-248 (l)-9 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-249 (l)-9 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B1-251 (l)-9 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-252 (l)-9 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-253 (l)-9 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
  • B 1-254 (l)-9 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
  • B 1 -259 (l)-9 (ll)-27 preferably 20:1 to 1 :20
  • B 1 -260 (l)-9 (ll)-28 preferably 20:1 to 1 :20
  • B1 -261 (l)-9 (ll)-29 preferably 20:1 to 1 :20
  • compositions according to the invention are suitable as fungicides. They are distinguished by an outstanding effectiveness against a broad spectrum of phytopatho- genic fungi, including soil-borne fungi, which derive especially from the classes of the Plasmodiophoromycetes, Peronosporomycetes (syn. Oomycetes), Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes and Deuteromycetes (syn. Fungi imper- fecti). Some are systemically effective and they can be used in crop protection as foliar fungicides, fungicides for seed dressing and soil fungicides. Moreover, they are suitable for controlling phytopathogenic fungi, which inter alia occur in wood or roots of plants.
  • compositions according to the invention are particularly important in the control of a multitude of phytopathogenic fungi on various cultivated plants, such as cereals, e. g. wheat, rye, barley, triticale, oats or rice; beet, e. g. sugar beet or fodder beet; fruits, such as pomes, stone fruits or soft fruits, e. g.
  • cereals e. g. wheat, rye, barley, triticale, oats or rice
  • beet e. g. sugar beet or fodder beet
  • fruits such as pomes, stone fruits or soft fruits, e. g.
  • the inventive compositions are used for controlling a multitude of fungi on field crops, such as potatoes sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rape, legumes, sunflowers, coffee or sugar cane; fruits; vines; ornamentals; or vegetables, such as cucumbers, tomatoes, beans or squashes.
  • field crops such as potatoes sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rape, legumes, sunflowers, coffee or sugar cane; fruits; vines; ornamentals; or vegetables, such as cucumbers, tomatoes, beans or squashes.
  • plant propagation material is to be understood to denote all the generative parts of the plant such as seeds and vegetative plant material such as cuttings and tubers (e. g. potatoes), which can be used for the multiplication of the plant. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants, including seedlings and young plants, which are to be transplanted after germination or after emergence from soil. These young plants may also be protected before transplantation by a total or partial treatment by immersion or pouring.
  • treatment of plant propagation materials with compound (I) and compound (II) and/or a composition comprising said compounds, respectively, is used for controlling a multitude of fungi on cereals, such as wheat, rye, barley and oats; rice, corn, cotton and soybeans.
  • cultiva plants is to be understood as including plants which have been modified by breeding, mutagenesis or genetic engineering including but not limiting to agricultural biotech products on the market or in development (cf.
  • Genetically modified plants are plants, which genetic material has been so modified by the use of recombinant DNA techniques that under natural circumstances cannot readily be obtained by cross breeding, mutations or natural recombination. Typically, one or more genes have been integrated into the genetic material of a genetically modified plant in order to improve certain properties of the plant.
  • Such genetic modifications also include but are not limited to targeted post-translational modification of protein(s), oligo- or polypeptides e. g. by glycosylation or polymer additions such as prenylated, acetylated or farnesylated moieties or PEG moieties.
  • herbicides e. bromoxynil or ioxynil herbicides as a result of conventional methods of breeding or genetic engineering. Furthermore, plants have been made resistant to multiple classes of herbicides through multiple genetic modifications, such as resistance to both glyphosate and glufosinate or to both glyphosate and a herbicide from another class such as ALS inhibitors, HPPD inhibitors, auxin herbicides, or AC- Case inhibitors. These herbicide resistance technologies are e. g. described in Pest Managem. Sci. 61 , 2005, 246; 61 , 2005, 258; 61 , 2005, 277; 61 , 2005, 269; 61 , 2005, 286; 64, 2008, 326; 64, 2008, 332; Weed Sci.
  • Several culti- vated plants have been rendered tolerant to herbicides by conventional methods of breeding (mutagenesis), e. g. Clearfield ® summer rape (Canola, BASF SE, Germany) being tolerant to imidazolinones, e. g. imazamox, or ExpressSun ® sunflowers (DuPont, USA) being tolerant to sulfonyl ureas, e. g. tribenuron.
  • mutagenesis e. g. Clearfield ® summer rape (Canola, BASF SE, Germany) being tolerant to imidazolinones, e. g. imazamox, or ExpressSun ® sunflowers (DuPont, USA) being tolerant to sulfonyl ureas, e. g. tribenuron.
  • plants are also covered that are by the use of recombinant DNA tech- niques capable to synthesize one or more insecticidal proteins, especially those known from the bacterial genus Bacillus, particularly from Bacillus thuringiensis, such as ⁇ - endotoxins, e. g. CrylA(b), CrylA(c), CrylF, CrylF(a2), CryllA(b), CrylllA, CrylllB(bl ) or Cry9c; vegetative insecticidal proteins (VIP), e. g. VIP1 , VIP2, VIP3 or VIP3A; insecticidal proteins of bacteria colonizing nematodes, e. g. Photorhabdus spp.
  • VIP1 , VIP2, VIP3 or VIP3A vegetative insecticidal proteins
  • toxins produced by animals such as scorpion toxins, arachnid toxins, wasp toxins, or other insect-specific neurotoxins
  • toxins produced by fungi such Streptomy- cetes toxins, plant lectins, such as pea or barley lectins; agglutinins
  • proteinase inhibitors such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin or papain inhibitors
  • ribosome-inactivating proteins (RIP) such as ricin, maize-RIP, abrin, luffin, saporin or bryodin
  • steroid metabolism enzymes such as 3-hydroxysteroid oxidase, ecdysteroid-IDP-glycosyl-transferase, cholesterol oxidases, ecdysone inhibitors or HMG-CoA-reductase
  • ion channel blockers such as blockers of sodium
  • these insecticidal proteins or toxins are to be understood expressly also as pre-toxins, hybrid proteins, truncated or otherwise modified proteins.
  • Hybrid proteins are characterized by a new combination of protein domains, (see, e. g. WO 02/015701 ).
  • Further examples of such toxins or genetically modified plants capable of synthesizing such toxins are disclosed, e. g., in EP-A 374 753, WO 93/007278, WO 95/34656, EP-A 427 529, EP-A 451 878, WO 03/18810 und WO 03/52073.
  • the methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e. g.
  • insecticidal proteins contained in the genetically modified plants impart to the plants producing these proteins tolerance to harmful pests from all taxonomic groups of athropods, especially to beetles (Coeloptera), two-winged insects (Diptera), and moths (Lepidoptera) and to nematodes (Nematoda).
  • Genetically modified plants capable to synthesize one or more insecticidal proteins are, e.
  • WO 03/018810 MON 863 from Monsanto Europe S.A., Belgium (corn cultivars producing the Cry3Bb1 toxin), IPC 531 from Monsanto Europe S.A., Belgium (cotton cultivars producing a modified version of the CrylAc toxin) and 1507 from Pioneer Overseas Corporation, Belgium (corn cultivars producing the Cry1 F toxin and PAT enzyme).
  • plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the resistance or tolerance of those plants to bacterial, viral or fungal pathogens.
  • proteins are the so-called “pathogenesis-related proteins” (PR proteins, see, e. g.
  • EP-A 392 225 plant disease resistance genes (e. g. potato cultivars, which express resistance genes acting against Phytophthora infestans derived from the mexican wild potato Solanum bulbocastanum) or T4-lysozym (e. g. potato cultivars capable of synthesizing these proteins with increased resistance against bacteria such as Erwinia amylvora).
  • plant disease resistance genes e. g. potato cultivars, which express resistance genes acting against Phytophthora infestans derived from the mexican wild potato Solanum bulbocastanum
  • T4-lysozym e. g. potato cultivars capable of synthesizing these proteins with increased resistance against bacteria such as Erwinia amylvora.
  • the methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e. g. in the publications mentioned above.
  • plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the productivity (e. g. bio mass production, grain yield, starch content, oil content or protein content), toler- ance to drought, salinity or other growth-limiting environmental factors or tolerance to pests and fungal, bacterial or viral pathogens of those plants.
  • productivity e. g. bio mass production, grain yield, starch content, oil content or protein content
  • plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve human or animal nutrition, e. g. oil crops that produce health- promoting long-chain omega-3 fatty acids or unsaturated omega-9 fatty acids (e. g. Nexera ® rape, DOW Agro Sciences, Canada).
  • plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve raw material production, e. g. potatoes that produce increased amounts of amylopectin (e. g. Amflora ® potato, BASF SE, Germany).
  • a modified amount of substances of content or new substances of content specifically to improve raw material production, e. g. potatoes that produce increased amounts of amylopectin (e. g. Amflora ® potato, BASF SE, Germany).
  • compositions are particularly suitable for controlling the following plant diseases:
  • Albugo spp. (white rust) on ornamentals, vegetables (e. g. A. Candida) and sunflowers (e. g. A. tragopogonis); Alternaria spp. (Alternaria leaf spot) on vegetables, rape (A. brassicola or brassicae), sugar beets (A. tenuis), fruits, rice, soybeans, potatoes (e. g. A. solani or A. alternata), tomatoes (e. g. A. solani or A. alternata) and wheat; Aphano- myces spp. on sugar beets and vegetables; Ascochyta spp. on cereals and vegetables, e. g. A. tritici (anthracnose) on wheat and A.
  • Bipolaris and Drechslera spp. (teleomorph: Cochliobolus spp.), e. g. Southern leaf blight (D. maydis) or Northern leaf blight (B. zeicola) on corn, e. g. spot blotch (B. sorokiniana) on cereals and e.g. B. oryzae on rice and turfs; Blumeria (formerly Erysiphe) graminis (powdery mildew) on cereals (e. g. on wheat or barley); Botrytis cinerea (teleomorph: Botryotinia fuckeliana: grey mold) on fruits and berries (e. g.
  • strawberries strawberries
  • vegetables e. g. lettuce, carrots, celery and cabbages
  • rape flowers, vines, forestry plants and wheat
  • Bremia lactucae downy mildew
  • Ceratocystis syn. Ophiostoma
  • spp. rot or wilt
  • broad- leaved trees and evergreens e. g. C. ulmi (Dutch elm disease) on elms
  • Cercospora spp. Cercospora leaf spots
  • corn e.g. Gray leaf spot: C. zeae-maydis
  • sugar beets e. g. C.
  • Colletotrichum teleomorph: Glomerella
  • spp. anthracnose
  • cotton e. g. C. gossypii
  • corn e. g. C. graminicola: Anthracnose stalk rot
  • soft fruits e. g. C. coccodes: black dot
  • beans e. g. C. Iindemuthianum
  • soybeans e. g. C. truncatum or C. gloeosporioides
  • Corticium spp. e. g. C.
  • sa- sakii sheath blight
  • Corynespora cassiicola leaf spots
  • Cycloconium spp. e. g. C. oleaginum on olive trees
  • Cylindrocarpon spp. e. g. fruit tree canker or young vine decline, teleomorph: Nectria or Neonectria spp.
  • liriodendri Neonectria liriodendri: Black Foot Disease) and ornamentals; Dematophora (teleomorph: Rosellinia) necatrix (root and stem rot) on soybeans; Diaporthe spp., e. g. D. phaseolorum (damping off) on soy- beans; Drechslera (syn. Helminthosporium, teleomorph: Pyrenophora) spp. on corn, cereals, such as barley (e. g. D. teres, net blotch) and wheat (e. g. D. D.
  • tritici-repentis tan spot), rice and turf; Esca (dieback, apoplexy) on vines, caused by Formitiporia (syn. Phellinus) punctata, F. mediterranea, Phaeomoniella chlamydospora (earlier Phaeo- acremonium chlamydosporum), Phaeoacremonium aleophilum and/or Botryosphaeria obtusa; Elsinoe spp. on pome fruits (E. pyri), soft fruits (E. veneta: anthracnose) and vines (E.
  • ampelina anthracnose
  • Entyloma oryzae leaf smut
  • Epicoccum spp. black mold
  • Erysiphe spp. potowdery mildew
  • sugar beets E. betae
  • vegetables e. g. E. pisi
  • cucurbits e. g. E. cichoracearum
  • cabbages e. g. E. cruciferarum
  • Eutypa lata Eutypa canker or dieback, anamorph: Cytosporina lata, syn.
  • Drechslera, teleomorph Cochliobolus) on corn, cereals and rice; Hemileia spp., e. g. H. vastatrix (coffee leaf rust) on coffee; Isariopsis clavispora (syn. Cladosporium vitis) on vines; Macrophomina phaseolina (syn. phaseoli) (root and stem rot) on soybeans and cotton; Microdochium (syn. Fusarium) nivale (pink snow mold) on cereals (e. g. wheat or barley); Microsphaera diffusa (powdery mildew) on soybeans; Monilinia spp., e. g. M.
  • phaseoli, teleomorph Diaporthe phaseolorum
  • Physoderma maydis brown spots
  • Phytophthora spp. wilt, root, leaf, fruit and stem root
  • various plants such as paprika and cucurbits (e. g. P. capsici), soybeans (e. g. P. megasperma, syn. P. sojae), potatoes and tomatoes (e. g. P. infestans: late blight) and broad-leaved trees (e. g. P. ramorum: sudden oak death);
  • Plasmodiophora brassicae club root
  • cabbage rape, radish and other plants
  • Plasmopara spp. e.
  • wheat or barley Pseudoperonospora (downy mildew) on various plants, e. g. P. cubensis on cucurbits or P. humili on hop; Pseudopezicula tracheiphila (red fire disease or .rotbrenner', anamorph: Phialophora) on vines; Puccinia spp. (rusts) on various plants, e. g. P. triticina (brown or leaf rust), P. striiformis (stripe or yellow rust), P. hordei (dwarf rust), P. graminis (stem or black rust) or P.
  • P. triticina brown or leaf rust
  • P. striiformis stripe or yellow rust
  • P. hordei dwarf rust
  • P. graminis seed or black rust
  • recondita brown or leaf rust
  • cereals such as e. g. wheat, barley or rye, P. kuehnii (orange rust) on sugar cane and P. asparagi on asparagus
  • Pyrenophora anamorph: Drechslera
  • tritici-repentis tan spot
  • P. teres net blotch
  • Pyricularia spp. e. g. P. oryzae (teleomorph: Magnaporthe grisea, rice blast) on rice and P. grisea on turf and cereals
  • solani (sheath blight) on rice or R. cerealis (Rhizoctonia spring blight) on wheat or barley; Rhizopus stolonifer (black mold, soft rot) on strawberries, carrots, cabbage, vines and tomatoes; Rhynchosporium secalis (scald) on barley, rye and triti- cale; Sarocladium oryzae and S. attenuatum (sheath rot) on rice; Sclerotinia spp. (stem rot or white mold) on vegetables and field crops, such as rape, sunflowers (e. g. S. sclerotiorum) and soybeans (e. g. S. rolfsii or S.
  • rape sunflowers
  • sunflowers e. g. S. sclerotiorum
  • soybeans e. g. S. rolfsii or S.
  • Septoria spp. on various plants, e. g. S. glycines (brown spot) on soybeans, S. tritici (Septoria blotch) on wheat and S. (syn. Stagonospora) nodorum (Stagonospora blotch) on cereals; Uncinula (syn. Erysiphe) necator (powdery mildew, anamorph: Oidium tuckeri) on vines; Setospaeria spp. (leaf blight) on corn (e. g. S. turcicum, syn.
  • Sphacelotheca spp. (smut) on corn, (e. g. S. reiliana: head smut), sorghum und sugar cane; Sphaerotheca fuliginea (powdery mildew) on cucurbits; Spongospora subterra- nea (powdery scab) on potatoes and thereby transmitted viral diseases; Stagonospora spp. on cereals, e. g. S. nodorum (Stagonospora blotch, teleomorph: Leptosphaeria [syn.
  • T. deformans leaf curl disease
  • T. pruni plum pocket
  • Thielaviopsis spp. black root rot
  • tobacco, pome fruits, vegetables, soybeans and cotton e. g. T. basico
  • controversa dwarf bunt
  • Typhula incarnata grey snow mold
  • Urocystis spp. e. g. U. occulta (stem smut) on rye
  • Uromyces spp. rust on vegetables, such as beans (e. g. U. appendiculatus, syn. U. phaseoli) and sugar beets (e. g. U. betae)
  • Ustilago spp. loose smut) on cereals (e. g. U. nuda and U. avaenae), corn (e. g. U. maydis: corn smut) and sugar cane; Venturia spp.
  • compositions are also suitable for controlling phytopathogenic fungi in the protection of stored products or harvest and in the protection of materials.
  • protection of materials is to be understood to denote the protection of technical and non-living materials, such as adhesives, glues, wood, paper and paperboard, textiles, leather, paint dispersions, plastics, colling lubricants, fiber or fabrics, against the infestation and destruction by harmful microorganisms, such as fungi and bacteria.
  • Ascomycetes such as Ophiostoma spp., Ceratocystis spp., Aureobasidium pullulans, Sclerophoma spp., Chaetomium spp., Humicola spp., Petriella spp., Trichurus spp.; Basidiomycetes such as Coniophora spp., Coriolus spp., Gloeophyllum spp., Lentinus spp., Pleurotus spp., Poria spp., Serpula spp.
  • compositions of the invention are especially suitable in the control of Plasmopara spp., for example P. viticola.
  • compositions of the invention are especially suitable in the control of Phytophthora spp., for example P. infestans: late blight.
  • compositions of the invention are especially suitable in the control of Peronospora spp. (downy mildew), for eample P. brassicae and P. destructor.
  • compositions of the invention are especially suitable in the control of leaf spots in various cultivated plants, for example Alternaria spp. (Alternaria leaf spot) A. solani or A. alternata, A. brassicola or brassica- e.
  • compositions of the invention are especially suitable in the control of Pseudoperonospora (downy mildew) on various plants.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on vines (table grapes and grape juice grape vines).
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on potatoes.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on rapeseed (in particular canola, oilseed-rape).
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on beans.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on artichoke.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on asparagus.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on beetroot.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on broccoli. According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on brussels sprouts.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on cabbage.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on cauliflower.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on celery.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on chicory.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on chives.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on cress.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on cucumbers.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on eggplant.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on endive and chicory.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on fennel.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on garlic.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on gourd.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on kohlrabi.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on lettuce.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on leeks.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on melon.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on onion.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on parsley.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on peas.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on pepper.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on punpkin.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on radish.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on rhubarb.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on shallot.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on spinach.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on tomato.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on watermelon.
  • compositions of the invention are especially suitable in the control of phytopathogenic fungi on zucchini.
  • the inventive compositions are used for controlling a multitude of fungi on field crops, such as potatoes, rape, legumes; fruits; vines; or vegetables, such as cucumbers, tomatoes, beans or squashes.
  • Preferred cultivated plants that can be protected and/or cured according to the present invention are vines, potatoes, rapeseed, in particular canola, oilseed-rape, beans, cucumbers, melon, peas, spinach, tomato and watermelon.
  • the inventive compositions may also be used for improving the health of a plant.
  • the invention also relates to a method for improving plant health by treating a plant, its propagation material and/or the locus where the plant is growing or is to grow with an effective amount of an inventive composition.
  • plant health is to be understood to denote a condition of the plant and/or its products which is determined by several indicators alone or in combination with each other such as yield (e. g. increased biomass and/or increased content of valuable ingredients), plant vigor (e. g. improved plant growth and/or greener leaves ("greening effect")), quality (e. g. improved content or composition of certain ingredients) and tolerance to abiotic and/or biotic stress.
  • yield e. g. increased biomass and/or increased content of valuable ingredients
  • plant vigor e. g. improved plant growth and/or greener leaves ("greening effect")
  • quality e. g. improved content or composition of certain ingredients
  • tolerance to abiotic and/or biotic stress e. g. improved content or composition of certain ingredients
  • compositions comprising said modifications are likewise subject matter of the present invention.
  • compositions can be carried out both before and af- ter the infection of the plants, plant propagation materials, such as seeds, soil, surfaces, materials or rooms by the fungi.
  • Plant propagation materials may be treated with the inventive compositions prophy- lactically either at or before planting or transplanting.
  • the invention also relates to agrochemical compositions comprising a solvent or solid carrier and at least one composition of the invention and to the use for controlling phytopathogenic fungi.
  • An agrochemical composition comprises a fungicidally effective amount of an inven- tive composition.
  • fungicidally effective amount denotes an amount of the composition, which is sufficient for controlling phytopathogenic fungi on cultivated plants or in the protection of materials and which does not result in a substantial damage to the treated plants. Such an amount can vary in a broad range and is dependent on various factors, such as the fungal species to be controlled, the treated cultivated plant or material, the climatic conditions and the specific composition used.
  • compositions comprising a compound (I) and/or a N-oxide or salt thereof and a compound (II) and/or a N-oxide or salt thereof can be converted into customary types of agrochemical compositions, e. g. solutions, emulsions, suspensions, dusts, powders, pastes and granules.
  • agrochemical compositions e. g. solutions, emulsions, suspensions, dusts, powders, pastes and granules.
  • the composition type depends on the particular intended purpose; in each case, it should ensure a fine and uniform distribution of the components used according to the invention.
  • composition types are suspensions (SC, OD, FS), emulsifiable concentrates (EC), emulsions (EW, EO, ES), pastes, pastilles, wettable powders or dusts (WP, SP, SS, WS, DP, DS) or granules (GR, FG, GG, MG), which can be water- soluble or wettable, as well as gel formulations for the treatment of plant propagation materials such as seeds (GF).
  • composition types e. g. SC, OD, FS, EC, WG, SG, WP, SP, SS, WS, GF
  • composition types such as DP, DS, GR, FG, GG and MG are usually used undiluted.
  • compositions are prepared in a known manner (cf. US 3,060,084,
  • the agrochemical compositions may also comprise auxiliaries which are customary in agrochemical compositions.
  • auxiliaries depend on the particular application form and active substances, respectively.
  • auxiliaries are solvents, solid carriers, dispersants or emulsi- fiers (such as further solubilizers, protective colloids, surfactants and adhesion agents), organic and anorganic thickeners, bactericides, anti-freezing agents, anti-foaming agents, if appropriate colorants and tackifiers or binders (e. g. for seed treatment formulations).
  • Suitable solvents are water, organic solvents such as mineral oil fractions of medium to high boiling point, such as kerosene or diesel oil, furthermore coal tar oils and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons, e. g.
  • Solid carriers are mineral earths such as silicates, silica gels, talc, kaolins, limestone, lime, chalk, bole, loess, clays, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers, such as, e. g., ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and products of vegetable origin, such as cereal meal, tree bark meal, wood meal and nutshell meal, cellulose powders and other solid carriers.
  • mineral earths such as silicates, silica gels, talc, kaolins, limestone, lime, chalk, bole, loess, clays, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers, such as, e. g., ammonium sulfate, ammonium phosphat
  • Suitable surfactants are alkali metal, alkaline earth metal and ammonium salts of aromatic sulfonic acids, such as ligninsoulfonic acid (Borresperse ® types, Borregard, Norway) phenolsulfonic acid, naphthalenesulfonic acid (Morwet ® types, Akzo Nobel, U.S.A.), dibutylnaphthalene- sulfonic acid (Nekal ® types, BASF, Germany), and fatty acids, alkylsulfonates, alkyl- arylsulfonates, alkyl sulfates, laurylether sulfates, fatty alcohol sulfates, and sulfated hexa-, hepta- and octadecanolates, sulfated fatty alcohol glycol ethers,
  • aromatic sulfonic acids such as ligninsoulfonic acid (Borresperse
  • methylcellulose g. methylcellulose
  • hydrophobically modified starches polyvinyl alcohols (Mowiol ® types, Clariant, Switzerland), polycarboxylates (Sokolan ® types, BASF, Germany), polyalkoxylates, polyvinyl- amines (Lupasol ® types, BASF, Germany), polyvinylpyrrolidone and the copolymers therof.
  • thickeners i. e. compounds that impart a modified flowability to compositions, i. e. high viscosity under static conditions and low viscosity during agitation
  • thickeners are polysaccharides and organic and anorganic clays such as Xanthan gum (Kelzan ® , CP Kelco, U.S.A.), Rhodopol ® 23 (Rhodia, France), Veegum ® (R.T. Vanderbilt, U.S.A.) or Attaclay ® (Engelhard Corp., NJ, USA).
  • Bactericides may be added for preservation and stabilization of the composition.
  • suitable bactericides are those based on dichlorophene and benzyl- alcohol hemi formal (Proxel ® from ICI or Acticide ® RS from Thor Chemie and Kathon ® MK from Rohm & Haas) and isothiazolinone derivatives such as alkylisothiazolinones and benzisothiazolinones (Acticide ® MBS from Thor Chemie).
  • Suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.
  • anti-foaming agents examples include silicone emulsions (such as e. g. Silikon ® SRE, Wacker, Germany or Rhodorsil ® , Rhodia, France), long chain alcohols, fatty acids, salts of fatty acids, fluoroorganic compounds and mixtures thereof.
  • Suitable colorants are pigments of low water solubility and water-soluble dyes. Examples to be mentioned are rhodamin B, C. I. pigment red 1 12, C. I. solvent red 1 , pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1 , pigment blue 80, pigment yellow 1 , pigment yellow 13, pigment red 1 12, pigment red 48:2, pigment red 48:1 , pigment red 57:1 , pigment red 53:1 , pigment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment green 7, pigment white 6, pigment brown 25, basic violet 10, basic violet 49, acid red 51 , acid red 52, acid red 14, acid blue 9, acid yellow 23, basic red 10, basic red 108.
  • tackifiers or binders examples include polyvinylpyrrolidone, polyvinylacetates, polyvinyl alcohols and cellulose ethers (Tylose ® , Shin-Etsu, Japan).
  • Powders, materials for spreading and dusts can be prepared by mixing or concomitantly grinding the active compounds with at least one solid carrier.
  • Granules e. g. coated granules, impregnated granules and homogeneous granules, can be prepared by binding the active substances to solid carriers.
  • solid carriers are mineral earths such as silica gels, silicates, talc, kaolin, attaclay, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers, such as, e.
  • ammonium sulfate ammonium phosphate, ammonium nitrate, ureas
  • products of vegetable origin such as cereal meal, tree bark meal, wood meal and nutshell meal, cellulose powders and other solid carriers.
  • composition types are:
  • compositions according to the invention 10 parts by weight of a composition according to the invention are dissolved in 90 parts by weight of water or in a water-soluble solvent.
  • wetting agents or other auxiliaries are added.
  • the active substances dissolve upon dilution with water. In this way, a composition having a content of 10% by weight of active substances is obtained.
  • a composition according to the invention 20 parts by weight of a composition according to the invention are dissolved in 70 parts by weight of cyclohexanone with addition of 10 parts by weight of a dispersant, e. g. polyvinylpyrrolidone. Dilution with water gives a dispersion.
  • the active substances content is 20% by weight.
  • compositions according to the invention 15 parts by weight of a composition according to the invention are dissolved in 75 parts by weight of xylene with addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (in each case 5 parts by weight). Dilution with water gives an emulsion.
  • the composition has an active substances content of 15% by weight.
  • Emulsions (EW, EO, ES)
  • compositions according to the invention 25 parts by weight of a composition according to the invention are dissolved in 35 parts by weight of xylene with addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (in each case 5 parts by weight).
  • This mixture is introduced into 30 parts by weight of water by means of an emulsifying machine (Ultraturrax) and made into a homogeneous emulsion. Dilution with water gives an emulsion.
  • the composition has an active substances content of 25% by weight.
  • a composition according to the invention 20 parts by weight of a composition according to the invention are comminuted with addition of 10 parts by weight of dispersants and wetting agents and 70 parts by weight of water or an organic solvent to give a fine active sub- stances suspension. Dilution with water gives a stable suspension of the active composition.
  • the active substances content in the composition is 20% by weight.
  • compositions according to the invention are ground finely with addition of 50 parts by weight of dispersants and wetting agents and prepared as wa- ter-dispersible or water-soluble granules by means of technical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substances.
  • the composition has an active substances content of 50% by weight.
  • Water-dispersible powders and water-soluble powders (WP, SP, SS, WS) 75 parts by weight of a composition according to the invention are ground in a rotor- stator mill with addition of 25 parts by weight of dispersants, wetting agents and silica gel. Dilution with water gives a stable dispersion or solution of the active substances.
  • the active substances content of the composition is 75% by weight.
  • a composition according to the invention 20 parts by weight of a composition according to the invention are comminuted with addition of 10 parts by weight of dispersants, 1 part by weight of a gelling agent wetters and 70 parts by weight of water or of an organic solvent to give a fine suspension of the active substances. Dilution with water gives a stable suspension of the active substances, whereby a composition with 20% (w/w) of active substances is obtained.
  • Dustable powders (DP, DS)
  • composition according to the invention 5 parts by weight of a composition according to the invention are ground finely and mixed intimately with 95 parts by weight of finely divided kaolin. This gives a dustable composition having an active substances content of 5% by weight.
  • a composition according to the invention is ground finely and associated with 99.5 parts by weight of carriers.
  • Current methods are extrusion, spray- drying or the fluidized bed. This gives granules to be applied undiluted having an active substances content of 0.5% by weight.
  • compositions according to the invention 10 parts by weight of a composition according to the invention are dissolved in 90 parts by weight of an organic solvent, e. g. xylene. This gives a composition to be ap- plied undiluted having an active substances content of 10% by weight.
  • an organic solvent e. g. xylene
  • the agrochemical compositions generally comprise between 0.01 and 95%, preferably between 0.1 and 90%, most preferably between 0.5 and 90%, by weight of ac- tive substances.
  • the active substances are usually employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).
  • Water-soluble concentrates (LS), flowable concentrates (FS), powders for dry treatment (DS), water-dispersible powders for slurry treatment (WS), water-soluble powders (SS), emulsions (ES) emulsifiable concentrates (EC) and gels (GF) are usu- ally employed for the purposes of treatment of plant propagation materials, particularly seeds.
  • These compositions can be applied to plant propagation materials, particularly seeds, diluted or undiluted.
  • the compositions in question give, after two-to-tenfold dilution, active substances concentrations of from 0.01 to 60% by weight, preferably from 0.1 to 40% by weight, in the ready-to-use preparations. Application can be carried out before or during sowing.
  • Methods for applying the compounds of the inventive compositions on to plant propagation material, especially seeds are known in the art, and include dressing, coating, pelleting, dusting, soaking and in-furrow application methods of the propagation material.
  • the compounds of the inventive compositions are applied on to the plant propagation material by a method such that germination is not induced, e. g. by seed dressing, pelleting, coating and dusting.
  • a suspension-type (FS) composition is used for seed treatment.
  • a FS composition may comprise 1 -800 g/l of active substances, 1 -200 g/l Surfactant, 0 to 200 g/l antifreezing agent, 0 to 400 g/l of binder, 0 to 200 g/l of a pigment and up to 1 liter of a solvent, preferably water.
  • the active substances of the inventive compositions can be used as such or in the form e. g. directly sprayable solutions, powders, suspensions, dispersions, emulsions, oil dispersions, pastes, dustable products, materials for spreading, or granules, by means of spraying, atomizing, dusting, spreading, brushing, immersing or pouring.
  • the application forms depend entirely on the intended purposes; it is intended to ensure in each case the finest possible distribution of the active substances used according to the invention.
  • Aqueous application forms can be prepared from emulsion concentrates, pastes or wettable powders (sprayable powders, oil dispersions) by adding water.
  • the substances as such or dissolved in an oil or solvent, can be homogenized in water by means of a wetter, tackifier, dispersant or emulsifier.
  • concentrates composed of active substances, wetter, tackifier, dispersant or emulsifier and, if appropriate, solvent or oil, and such concentrates are suitable for dilution with water.
  • the active substances concentrations in the ready-to-use preparations can be var- ied within relatively wide ranges. In general, they are from 0.0001 to 10%, preferably from 0.001 to 1 % by weight of active substances.
  • the active substances may also be used successfully in the ultra-low-volume process (ULV), it being possible to apply compositions comprising over 95% by weight of active substances, or even to apply the active substances without additives.
  • UUV ultra-low-volume process
  • the amounts of active substances applied are, depending on the kind of effect desired, from 0.001 to 2 kg per ha, preferably from 0.005 to 2 kg per ha, more preferably from 0.05 to 0.9 kg per ha, in particular from 0.1 to 0.75 kg per ha.
  • amounts of active substances of from 0.1 to 1000 g, preferably from 1 to 1000 g, more preferably from 1 to 100 g and most preferably from 5 to 100 g, per 100 kilogram of plant propagation material (preferably seed) are generally required.
  • the amount of active substances applied depends on the kind of application area and on the desired effect. Amounts customarily applied in the protection of materials are, e. g., 0.001 g to 2 kg, preferably 0.005 g to 1 kg, of active substances per cubic meter of treated material.
  • oils, wetters an/or adjuvants may be added to the active sub- stances or the compositions comprising them, if appropriate not until immediately prior to use (tank mix).
  • These agents can be admixed with the compositions according to the invention in a weight ratio of 1 :100 to 100:1 , preferably 1 :10 to 10:1.
  • Adjuvants which can be used are in particular organic modified polysiloxanes such as Break Thru S 240 ® ; alcohol alkoxylates such as Atplus 245 ® , Atplus MBA 1303 ® , Plurafac LF 300 ® and Lutensol ON 30 ® ; EO/PO block polymers, e. g. Pluronic RPE 2035 ® and Genapol B ® ; alcohol ethoxylates such as Lutensol XP 80 ® ; and dioctyl sul- fosuccinate sodium such as Leophen RA ® .
  • organic modified polysiloxanes such as Break Thru S 240 ®
  • alcohol alkoxylates such as Atplus 245 ® , Atplus MBA 1303 ® , Plurafac LF 300 ® and Lutensol ON 30 ®
  • EO/PO block polymers e. g. Pluronic RPE 2035 ® and Genapol B ®
  • the weight ratio of component (1 ) and component (2) generally depends from the properties of the active substances used, usually it is in the range of from 1 :500 to 500:1 , more particularly from 1 :100 to 100:1 , regularly in the range of from 1 :50 to 50:1 , preferably in the range of from 1 :20 to 20:1 , more preferably in the range of from 1 :10 to 10:1 and in particular in the range of from 1 :3 to 3:1 .
  • the components can be used individually or already partially or completely mixed with one another to prepare the composition according to the invention. It is also possible for them to be packaged and used further as combination composition such as a kit of parts.
  • kits may include one or more, including all, components that may be used to prepare a subject agrochemical composition.
  • kits may include one or two of the active substances and/or an adjuvant component.
  • One or more of the components may already be combined together or pre-formulated.
  • the components may already be combined together and as such are packaged in a single container such as a vial, bottle, can, pouch, bag or canister.
  • two or more components of a kit may be packaged separately, i. e., not pre-formulated.
  • kits may include one or more separate containers such as vials, cans, bottles, pouches, bags or canisters, each container containing a separate component for an agrochemical composition.
  • a component of the kit may be applied sepa- rately from or together with the further components or as a component of a combination composition according to the invention for preparing the composition according to the invention.
  • the user applies the composition according to the invention usually from a predos- age device, a knapsack sprayer, a spray tank or a spray plane.
  • the agrochemical composition is made up with water and/or buffer to the desired application concentration, it being possible, if appropriate, to add further auxiliaries, and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained.
  • 50 to 500 liters of the ready-to-use spray liquor are applied per hectare of agricultural useful area, preferably 100 to 400 liters.
  • composition according to the invention such as parts of a kit or parts of a binary mixture may be mixed by the user himself in a spray tank and further auxiliaries may be added, if appropriate (tank mix).
  • either individual components of the composition according to the invention or partially premixed components may be mixed by the user in a spray tank and further auxiliaries and additives may be added, if appropriate (tank mix).
  • either individual components of the composition according to the invention or partially premixed components e. g. components comprising (1 ) and/or component (2) can be applied jointly (e. .g. after tankmix) or consecutively.
  • inventive compositions exhibit also advantgeous action against animal pests from the following orders:
  • insects from the order of the lepidopterans for example Agrotis ypsi- Ion, Agrotis segetum, Alabama argillacea, Anticarsia gemmatalis, Argyresthia con-clerosislla, Autographa gamma, Bupalus piniarius, Cacoecia murinana, Capua reticulana, Cheimatobia brumata, Chonstoneura fumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea grandi- osella, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bou- liana, Feltia subterranea, Galleria mellonella, Grapholitha funebrana, Grapholitha mo- les
  • beetles Coldeoptera
  • Agrilus sinuatus for example Agrilus sinuatus, Agriotes lineatus, Agriotes ob- scurus, Amphimallus solstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum, Aphthona euphoridae, Athous haemorrhoidalis, Atomaria linearis, Blasto- phagus piniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum, Bruchus lentis, Byctiscus betulae, Cassida nebulosa, Cerotoma trifurcata, Cetonia aurata, Ceuthorrhynchus assimilis, Ceuthorrhynchus napi, Chaetocnema tibialis, Conoderus vespertinus, Crioceris asparagi, Ctenicera ssp
  • mosquitoes e.g. Aedes aegypti, Aedes albopictus, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Anopheles crucians, Anopheles albi- manus, Anopheles gambiae, Anopheles freeborni, Anopheles leucosphyrus, Anopheles minimus, Anopheles quadrimaculatus, Calliphora vicina, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Chrysops discalis, Chrysops silacea, Chrysops atlanticus, Cochliomyia hominivorax, Contarinia sorghicola Cordylobia anthropophaga, Culicoides furens, Culex pipiens, Culex nigripal
  • Thrips thrips (Thysanoptera), e.g. Dichromothrips corbetti, Dichromothrips ssp., Frank- liniella fusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri, Thrips oryzae, Thrips palmi and Thrips tabaci, termites (Isoptera), e.g.
  • Calotermes flavicollis Leucotermes flavipes, Heterotermes aureus, Reticulitermes flavipes, Reticulitermes virginicus, Reticulitermes lucifugus, Reticulitermes santonensis, Reticulitermes grassei, Termes natalensis, and Coptotermes formosanus, cockroaches (Blattaria - Blattodea), e.g. Blattella germanica, Blattella asahinae, Pe- riplaneta americana, Periplaneta japonica, Periplaneta brunnea, Periplaneta fuliggi- nosa, Periplaneta australasiae, and Blatta orientalis,
  • crickets grasshoppers, locusts (Orthoptera), e.g. Acheta domestica, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplus bivittatus, Melanoplus femurrubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Schistocerca americana, Schistocerca gregaria, Dociostaurus maroc- canus, Tachycines asynamorus, Oedaleus senegalensis, Zonozerus variegatus, Hiero- glyphus daganensis, Kraussaria angulifera, Calliptamus italicus, Chortoicetes terminif- era, and Locustana pardalina,
  • Arachnoidea such as arachnids (Acarina), e.g. of the families Argasidae, Ixodidae and Sarcoptidae, such as Amblyomma americanum, Amblyomma variegatum, Ambry- omma maculatum, Argas persicus, Boophilus annulatus, Boophilus decoloratus, Boophilus microplus, Dermacentor silvarum, Dermacentor andersoni, Dermacentor variabilis, Hyalomma truncatum, Ixodes ricinus, Ixodes rubicundus, Ixodes scapularis, Ixodes holocyclus, Ixodes pacificus, Ornithodorus moubata, Ornithodorus hermsi, Orni- thodorus turicata, Ornithonyssus bacoti, Otobius megnini, Dermanyss
  • Tetranychidae spp. such as Tetranychus cinnabarinus, Tetranychus kan- zawai, Tetranychus pacificus, Tetranychus telarius and Tetranychus urticae, Panony- chus ulmi, Panonychus citri, and Oligonychus pratensis; Araneida, e.g. Latrodectus mactans, and Loxosceles reclusa,
  • fleas e.g. Ctenocephalides felis, Ctenocephalides canis, Xenopsylla cheopis, Pulex irritans, Tunga penetrans, and Nosopsyllus fasciatus,
  • silverfish, firebrat e.g. Lepisma saccharina and Thermobia domestica, centipedes (Chilopoda), e.g. Scutigera coleoptrata,
  • Earwigs e.g. forficula auricularia
  • Pediculus humanus capitis e.g. Pediculus humanus capitis, Pediculus humanus corporis, Pthirus pubis, Haematopinus eurysternus, Haematopinus suis, Linognathus vituli, Bovi- cola bovis, Menopon gallinae, Menacanthus stramineus and Solenopotes capillatus.
  • compositions according to the invention can be applied to any and all developmental stages of pests, such as egg, larva, pupa, and adult.
  • the pests may be controlled by contacting the target pest, its food supply, habitat, breeding ground or its lo- cus with a pesticidally effective amount of the inventive compositions or pesticidal compositions.
  • Locus means a plant, plant propagation material (preferably seed), soil, area, material or environment in which a pest is growing or may grow.
  • pesticidally effective amount means the amount of the inventive com- positions or of pesticidal compositions needed to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target organism.
  • the pesticidally effective amount can vary for the various inventive compositions.
  • a pesticidally effective amount of the compositions will also vary according to the prevail- ing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, and the like.
  • the present invention also relates to a method for improving the health of plants, wherein the plant, the locus where the plant is growing or is expected to grow or plant propagation material, from which the plant grows, is treated with an plant health effective amount of an inventive mixture.
  • plant effective amount denotes an amount of the inventive mixtures, which is sufficient for achieving plant health effects as defined hereinbelow. More exemplary information about amounts, ways of application and suitable ratios to be used is given herein. Again, the skilled artisan is well aware of the fact that such an amount can vary in a broad range and is dependent on various factors, e.g. the treated cultivated plant or material and the climatic conditions.
  • inventive compositions are employed by treating the fungi or the plants, plant propagation materials (preferably seeds), materials or soil to be protected from fungal attack with a pesticidally effective amount of the active compounds.
  • the application can be carried out both before and after the infection of the materials, plants or plant propagation materials (preferably seeds) by the pests.
  • the application rates of the mix- tures according to the invention are usually from 0,3 g/ha to 2000 g/ha, preferably 5 g/ha to 2000 g/ha, more preferably from 50 to 900 g/ha, in particular from 50 to 750 g/ha.
  • the application rates of the compositions according to the invention are usually from 0,3 g/ha to 2000 g/ha, preferably 5 g/ha to 2000 g/ha, more preferably from 50 to 900 g/ha, in particular from 50 to 750 g/ha.
  • compositions can also be employed for protecting plants from attack or infestation by animal pests (insects, acarids or nematodes) comprising contacting a plant, or soil or water in which the plant is growing.
  • animal pests insects, acarids or nematodes
  • the term plant refers to an entire plant, a part of the plant or the propagation material of the plant.
  • compositions are effective through both contact (via soil, glass, wall, bed net, carpet, plant parts or animal parts), and ingestion (bait, or plant part) and through trophallaxis and transfer.
  • Preferred application methods are into water bodies, via soil, cracks and crevices, pastures, manure piles, sewers, into water, on floor, wall, or by perimeter spray application and bait.
  • the inventive mixtures are prepared into a bait preparation.
  • the bait can be a liquid, a solid or a semisolid preparation (e.g. a gel).
  • the bait employed in the composition is a product which is sufficiently attractive to incite insects such as ants, termites, wasps, flies, mosquitoes, crickets etc. or cockroaches to eat it.
  • This attractant may be chosen from feeding stimulants or para and / or sex phero- mones readily known in the art.
  • Methods to control infectious diseases transmitted by insects with the inventive mixtures and their respective compositions also comprise treating surfaces of huts and houses, air spraying and impregnation of curtains, tents, clothing items, bed nets, tsetse-fly trap or the like.
  • Insecticidal compositions for application to fibers, fabric, knitgoods, non- wovens, netting material or foils and tarpaulins preferably comprise a composition including the inventive mixtures, optionally a repellent and at least one binder.
  • the inventive compositions can be used for protecting wooden materials such as trees, board fences, sleepers, etc.
  • the quantity of active ingredient ranges from 0.0001 to 500 g per 100 m 2 , preferably from 0.001 to 20 g per 100 m 2 .
  • Customary application rates in the protection of materials are, for example, from
  • 0.01 g to 1000 g of active compound per m 2 treated material desirably from 0.1 g to 50 g per m 2 .
  • Insecticidal compositions for use in the impregnation of materials typically contain from 0.001 to 95 weight %, preferably from 0.1 to 45 weight %, and more preferably from 1 to 25 weight % of at least one repellent and / or insecticide.
  • the typical content of active ingredient is from 0.0001 weight % to 15 weight %, desirably from 0.001 weight % to 5% weight % of active compound.
  • the composition used may also comprise other additives such as a solvent of the active material, a flavoring agent, a preserving agent, a dye or a bitter agent. Its attractiveness may also be enhanced by a special color, shape or texture.
  • the content of the mixture of the active ingredients is from 0.001 to 80 weights %, preferably from 0.01 to 50 weight % and most preferably from 0.01 to 15 weight %.

Abstract

The present invention relates to pesticidal compositions comprising (1 ) a fungicidal compound (I) selected from inhibitors of phospholipid biosynthesis and cell wall deposition; and and as component (2) an insecticidal compound (II).

Description

Pesticidal compositions
Description The present invention relates to a composition comprising the following components (1 ) and (2):
(1 ) a fungicidal compound (I) selected from inhibitors of phospholipid biosynthesis and cell wall deposition; and
(2) an insecticidal compound (II) selected from the groups (A) to (F):
(A) acetylcholinesterase inhibitors, selected from carbamates, organopho- spates and triazamate;
(B) sodium channel modulators;
(C) insect growth regulators; (D) macrocyclic lactone insecticides;
(E) respiration inhibitors, selected from mitochondrial complex I inhibitors and mitochondrial complex II inhibitors; and (F) insecticides, selected from chlorfenapyr, fenbutatin oxide, indoxacarb, metaflumizone, pymetrozine, cyhexatin, diafenthiuron, propargite, ben- clothiaz, bifenazate, cartap, flonicamid, pyridalyl, thiocyclam, cyenopyrafen, dicofol, flupyrazofos, cyflumetofen, amidoflumet, imicyafos, bistrifluron and pyrifluquinazon; in a synergistically effective amount.
Moreover, the invention relates to a method for controlling pests, using the inventive compositions and to the use of component (1 ) and (2) for preparing such compositions, and also to pesticidal compositions comprising such compositions.
Within the meaning of the present invention the term 'pests' comprises animal pests and phytopathogenic fungi.
In one embodiment, the present invention provides methods for the control of animal pests (such as insects, acarids and/or nematodes) comprising contacting the ani- mal pest (the insect, acarid or nematode) or their food supply, habitat, breeding grounds or their locus with a pesticidally effective amount of an inventive composition.
Moreover, in another embodiment the present invention relates to a method of protecting plants from attack or infestation by animal pests (insects, acarids and/or nema- todes) comprising contacting the plant, or the soil or water in which the plant is growing, with a pesticidally effective amount of an inventive composition.
Additionally, the present invention also relates to a method for protecting plant propagation material from harmful insects, arachnids or nematodes comprising contact- ing the plant propagation material with an inventive composition in pesticidally effective amounts.
Moreover, the invention relates to a method for controlling phytopathogenic fungi using the inventive compositions and to the use of the component (1 ) and the component (2) for preparing such compositions, and also to pesticidal compositions compris- ing such compositions.
Additionally, the present invention also comprises a method for protecting plant propagation material from phytopathogenic fungi comprising contacting the plant propagation material with an inventive composition in pesticidally effective amounts.
The present invention further relates to plant-protecting active ingredient composi- tions having synergistically enhanced action of improving the health of plants and to a method of applying such inventive compositions to the plants.
The compounds of formula (I), (II) as well as their pesticidal action and methods for producing them are generally known. For instance, the commercially available compounds may be found in http://www.alanwood.net/pesticides/. Furthermore, they may be found in The Pesticide Manual, 14th Edition, British Crop Protection Council (2006) among other publications.
However, the specific compositions of the present invention, which are based on the presence of a compound (I) and a compound (II) are not disclosed therein.
One typical problem arising in the field of pest control lies in the need to reduce the dosage rates of the active ingredient in order to reduce or avoid unfavorable environmental or toxicological effects whilst still allowing effective pest control.
Another problem encountered concerns the need to have available pest control agents which are effective against a broad spectrum of pests, e.g. both animal pests and phytopathogenic fungi.
There also exists the need for pest control agents that combine knock-down activity with prolonged control, that is, fast action with long lasting action.
Another difficulty in relation to the use of pesticides is that the repeated and exclusive application of an individual pesticidal compound leads in many cases to a rapid selection of pests, that means animal pests, and phytopathogenic fungi, which have developed natural or adapted resistance against the active compound in question. Therefore there is a need for pest control agents that help prevent or overcome resistance.
It was therefore an object of the present invention to provide pesticidal mixtures which solve the problems outlined above.
It has been found within the framework of the present invention, that this object is in part or in whole achieved by the specific inventive compositions. Especially, it has been found that the inventive compositions show markedly enhanced action against pests compared to the control rates that are possible with the individual compounds when applied to plants, parts of plants, plant propagation materials (preferably seeds), or at their locus of growth.
It has been found that the action of the inventive compositions goes beyond the fungicidal and/or insecticidal action of the active compounds present in the mixture alone.
According to the present invention, compound (I) and the compound (II) may be applied simultaneously, that is jointly or separately, or may be applied successively. This allows enhanced control of pests, which means animal pests and/or phytopathogenic fungi, compared to the control rates that are possible with the individual compounds (synergistic compositions).
According to the present invention, the composition comprises as component (1 ) a fungicidal compound (I) selected from inhibitors of phospholipid biosynthesis and cell wall deposition.
According to one embodiment of the present invention, component (1 ) is selected from benthiavalicarb, dimethomorph, flumorph, iprovalicarb, mandipropamid, pyri- morph, valifenalate, N-(1 -(1 -(4-cyanophenyl)ethanesulfonyl)-but-2-yl) carbamic acid-(4- fluorophenyl) ester and 1 -(4-chloro-phenyl)-1 -(propin-2-yl-oxy)-3-(4-(3,4-dimethoxy- phenyl)-isoxazol-5-yl)-propan-2-one.
According to another embodiment of the present invention, component (1 ) is se- lected from dimethomorph, flumorph, iprovalicarb, mandipropamid and 1 -(4-chloro- phenyl)-1 -(propin-2-yl-oxy)-3-(4-(3,4-dimethoxy-phenyl)-isoxazol-5-yl)-propan-2-one.
Particularly, component (1 ) is dimethomorph.
According to the present invention, the composition comprises as component (2) an insecticidal compound (II) selected from the groups (A) to (F):
(A) acetylcholinesterase inhibitors, selected from carbamates, organophospates and triazamate; (B) sodium channel modulators;
(C) insect growth regulators;
(D) macrocyclic lactone insecticides;
(E) respiration inhibitors, selected from mitochondrial complex I inhibitors and mitochondrial complex II inhibitors; and
(F) insecticides, selected from chlorfenapyr, fenbutatin oxide, indoxacarb,
metaflumizone, pymetrozine, cyhexatin, diafenthiuron, propargite, benclothiaz, bifenazate, cartap, flonicamid, pyridalyl, thiocyclam, cyenopyrafen, dicofol, flu- pyrazofos, cyflumetofen, amidoflumet, imicyafos, bistrifluron and pyrifluquinazon. According to one embodiment of the present invention, component (2) is selected from from groups (A) to (F), wherein
(A) are carbamates, selected from alanycarb, aldicarb, bendiocarb, benfuracarb, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenoxycarb, furathiocarb, methio- carb, methomyl, oxamyl, pirimicarb, propoxur, thiodicarb; organophospates, selected from acephate, azamethiphos, azinphos-methyl, cadusafos, chlorfenvin- phos, chlorpyrifos, dimethoate, diazinon, dichlorvos, dicrotophos disulfoton, ethion, fenitrothion, fenthion, isoxathion, malathion, methamidophos, methi- dathion, methyl-parathion, mevinphos, monocrotophos, oxydemeton-methyl, parathion, phenthoate, phosalone, phorate, phosmet, phosphamidon, phoxim, pirimiphos-methyl, profenofos, prothiofos, tebupirimfos, terbufos, tetrachlorvin- phos, triazophos, trichlorfon; and triazamate; (B) are sodium channel modulators, selected from betacyfluthrin, bifenthrin, cyper- methrin, alpha-cypermethrin, zeta-cypermethrin, deltamethrin, esfen-valerate, etofenprox, lambda-cyhalothrin, permethrin, tefluthrin, cyfluthrin, acrinathrin, al- lethrin, cycloprothrin, cyhalothrin, cyphenothrin, beta-cypermethrin, fenpropathrin, fenvalerate, flucythrinate, imiprothrin, prallethrin, pyrethrin I and II, resmethrin, si- lafluofen, tau-fluvalinate, tetramethrin, tralomethrin, transfluthrin, profluthrin, di- mefluthrin, gamma-cyhalothrin, theta-cypermethrin;
(C) are insect growth regulators, selected from flufenoxuron, lufenuron, novaluron, buprofezin, teflubenzuron, methoxyfenozide, chlorfluazuron, cyramazin, diflubenzuron, flucycloxuron, hexaflumuron, triflumuron; diofenolan, hexythiazox, etoxazole, clofentezine, halofenozide, tebufenozide, azadirachtin, pyriproxyfen, methoprene, spirodiclofen, spiromesifen, spirotetramat;
(D) are macrocyclic lactone insecticides, selected from abamectin, emamectin, mil- bemectin, lepimectin, spinetoram, spinosad;
(E) are mitochondrial complex I inhibitors, selecetd from fenazaquin, pyridaben, tolf- enpyrad, flufenerim, tebufenpyrad; and mitochondrial complex II inhibitors, selected from acequinocyl, fluacyprim, hydramethylnon, 2,2-Dimethyl-propionic acid (Z)-2-cyano-1 -(2-methyl-4-trifluoromethyl-thiazol-5-yl)-2-(2-phenyl-thiazol-4-yl)- vinyl ester; and
(F) are insecticides, selected from chlorfenapyr, fenbutatin oxide, indoxacarb,
metaflumizone, pymetrozine, cyhexatin, diafenthiuron, propargite, benclothiaz, bifenazate, cartap, flonicamid, pyridalyl, thiocyclam, cyenopyrafen, dicofol, flu- pyrazofos, cyflumetofen, amidoflumet, imicyafos, bistrifluron, pyrifluquinazon. According to one embodiment of the invention, the above active ingredient groups, (B), (D) and (F) are defined as follows: are sodium channel modulators, selected from bifenthrin, cypermethrin, zeta- cypermethrin, deltamethrin, esfen-valerate, etofenprox, lambda-cyhalothrin, per- methrin, cyfluthrin, acrinathrin, allethrin, cycloprothrin, cyhalothrin, cyphenothrin, beta-cypermethrin, fenpropathrin, fenvalerate, flucythrinate, imiprothrin, pral- lethrin, pyrethrin I and II, resmethrin, silafluofen, tau-fluvalinate, tetramethrin, tralomethrin, transfluthrin, profluthrin, dimefluthrin, gamma-cyhalothrin and theta- cypermethrin; in another specific embodiment, (B) is thereby defined as sodium channel modulators, selected from bifenthrin, cypermethrin, zeta-cypermethrin, deltamethrin, esfen-valerate, etofenprox, lambda-cyhalothrin, permethrin, acrinathrin, allethrin, cycloprothrin, cyhalothrin, cyphenothrin, beta-cypermethrin, fenpropathrin, fenvalerate, flucythrinate, imiprothrin, prallethrin, pyrethrin I and II, resmethrin, silafluofen, tau-fluvalinate, tetramethrin, tralomethrin, transfluthrin, profluthrin, dimefluthrin, gamma-cyhalothrin, theta-cypermethrin; are macrocyclic lactone insecticides, selected from, emamectin, milbemectin, lepimectin, spinetoram; are mitochondrial complex I inhibitors, selected from fenazaquin, pyridaben, tolf- enpyrad, flufenerim, tebufenpyrad; and mitochondrial complex II inhibitors, selected from acequinocyl, fluacyprim, hydramethylnon, 2,2-Dimethyl-propionic acid (Z)-2-cyano-1 -(2-methyl-4-trifluoromethyl-thiazol-5-yl)-2-(2-phenyl-thiazol-4-yl)- vinyl ester; and are insecticides, selected from chlorfenapyr, fenbutatin oxide, indoxacarb, py- metrozine, cyhexatin, diafenthiuron, propargite, benclothiaz, bifenazate, cartap, flonicamid, pyridalyl, thiocyclam, cyenopyrafen, dicofol, flupyrazofos, cyflumeto- fen, amidoflumet, imicyafos, bistrifluron, pyrifluquinazon.
Group (A) is in particular defined as a group consisting of aldicarb, carbofuran, carbosulfan, methiocarb, methomyl, thiodicarb, acephate, chlorpyrifos, dimethoate, malathion, methamidophos, profenofos and terbufos; more particularly aldicarb, carbo- furan, carbosulfan, methiocarb, thiodicarb and dimethoate; even more methiocarb and thiodicarb.
Group (B) is, according to a further inventive embodiment, in particular defined as a group consisting of bifenthrin, cypermethrin, alpha-cypermethrin, zeta-cypermethrin, deltamethrin, esfen-valerate, etofenprox, lambda-cyhalothrin, permethrin, tefluthrin, cyfluthrin and betacyfluthrin; more particularly bifenthrin, alpha-cypermethrin, deltamethrin, lambda-cyhalothrin, tefluthrin and betacyfluthrin.
Group (B) is, according to another inventive embodiment, in particular defined as a group consisting of bifenthrin, cypermethrin, zeta-cypermethrin, deltamethrin, esfen- valerate, etofenprox, lambda-cyhalothrin, permethrin and cyfluthrin; more particularly bifenthrin, deltamethrin and lambda-cyhalothrin.
Group (B) is, according to still another inventive embodiment, in particular defined as a group consisting of bifenthrin, cypermethrin, zeta-cypermethrin, deltamethrin, es- fen-valerate, etofenprox, lambda-cyhalothrin and permethrin; more particularly bifenthrin, deltamethrin and lambda-cyhalothrin.
Group (C) is in particular defined as a group consisting of flufenoxuron, lufenuron, novaluron, buprofezin, teflubenzuron and methoxyfenozide; more particularly flufenoxuron and methoxyfenozide.
Group (D) is, according to one embodiment, in particular defined as a group consisting of abamectin, emamectin, milbemectin, lepimectin and spinosad; more particularly abamectin, emamectina and spinosad; more specifically abamectin and spinosad.
Group (D) is, according to another embodiment, in particular defined as a group consisting of emamectin, milbemectin and lepimectin; specifically emamectin.
Group (E) is in particular defined as a group consisting of fenazaquin, tolfenpyrada and hydramethylnon; specifically hydramethylnon.
Group (F) is, according to one embodiment, in particular defined as a group consisting of chlorfenapyr, fenbutatin oxide, indoxacarb, metaflumizone, pymetrozine and pyridalyl; more particularly, chlorfenapyr, fenbutatin oxide, indoxacarb, metaflumizone, pymetrozine, specifically chlorfenapyr, metaflumizone and pymetrozine.
Group (F) is, according to another embodiment, in particular defined as being a group consisting of chlorfenapyr, fenbutatin oxide, indoxacarb, pymetrozine and pyridalyl; more particularly, chlorfenapyr, fenbutatin oxide, indoxacarb, and pymetrozine; specifically chlorfenapyr and pymetrozine.
Particularly preferred compositions of the present invention are mixtures, wherein component (1 ) is selected from compounds (l)-1 to (l)-9:
(l)-1 benthiavalicarb
(l)-2 dimethomorph
(l)-3 flumorph
(l)-4 iprovalicarb
(l)-5 mandipropamid
(l)-6 pyrimorph
(l)-7 valifenalate
(l)-8 N-(1 -(1 -(4-cyanophenyl)ethanesulfonyl)-but-2-yl) carbamic acid-(4-fluorophenyl)
(l)-9 1 -(4-chloro-phenyl)-1 -(propin-2-yl-oxy)-3-(4-(3,4-dimethoxy-phenyl)-isoxazol-5- yl)-propan-2-one
Furthermore, in preferred compositions of the invention, component (2) is selected from compounds (ll)-1 to (ll)-29:
(ll)-1 aldicarb (ll)-5 thiodicarb
(ll)-2 carbofuran 45 (ll)-6 dimethoate
(ll)-3 carbosulfan (ll)-7 bifenthrin
(ll)-4 methiocarb (ll)-8 cypermethrin l)-9 alpha-cypermethrin (ll)-20 methoxyfenozide l)-10 zeta-cypermethrin (ll)-21 abamectin
l)-11 deltamethrin (ll)-22 emamectin
l)-12 esfen-valerate 15 (ll)-23 spinosad
l)-13 etofenprox (ll)-24 hydramethylnon
l)-14 lambda-cyhalothrin (ll)-25 chlorfenapyr
l)-15 permethrin (ll)-26 fenbutatin oxide
l)-16 tefluthrin (\\)-27 indoxacarb
l)-17 cyfluthrin 20 (ll)-28 metaflumizone
(I l)-18 betacyfluthrin (ll)-29 pymetrozine.
(I l)-19 flufenoxuron
Particularly preferred compositions are the binary compositions B1-1 to B1-261 of table B1 , wherein each row corresponds to an embodiment of the inventive compositions.
Table B1: Binary compositions comprising as component (1) one of compounds (l)-1 to (l)-9 and a component (2) selected from one of compounds (ll)-1 to (ll)-29 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-1 (l)-1 (ll)-1 preferably 20:1 to 1:20,
more preferably 10:1 to 1:10
50:1 to 1:50
B1-2 (l)-1 (ll)-2 preferably 20:1 to 1:20,
more preferably 10:1 to 1:10
50:1 to 1:50
B1-3 (l)-1 (ll)-3 preferably 20:1 to 1:20,
more preferably 10:1 to 1:10
50:1 to 1:50
B1-4 (l)-1 (ll)-4 preferably 20:1 to 1:20,
more preferably 10:1 to 1:10
50:1 to 1:50
B1-5 (l)-1 (ll)-5 preferably 20:1 to 1:20,
more preferably 10:1 to 1:10
50:1 to 1:50
B1-6 (l)-1 (ll)-6 preferably 20:1 to 1:20,
more preferably 10:1 to 1:10
50:1 to 1:50
B1-7 (l)-1 (ll)-7 preferably 20:1 to 1:20,
more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-8 (l)-1 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-9 (l)-1 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-10 (l)-1 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-11 (l)-1 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-12 (l)-1 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-13 (l)-1 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-14 (l)-1 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-15 (l)-1 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-16 (l)-1 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-17 (l)-1 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-18 (l)-1 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-19 (l)-1 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-20 (l)-1 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-21 (l)-1 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-22 (l)-1 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-23 (l)-1 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-24 (l)-1 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-25 (l)-1 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-26 (l)-1 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-27 (l)-1 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-28 (l)-1 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-29 (l)-1 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-30 (l)-2 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-31 (l)-2 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-32 (l)-2 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-33 (l)-2 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-34 (l)-2 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-35 (l)-2 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-36 (l)-2 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-37 (l)-2 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-38 (l)-2 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-39 (l)-2 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-40 (l)-2 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-41 (l)-2 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-42 (l)-2 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-43 (l)-2 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-44 (l)-2 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-45 (l)-2 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-46 (l)-2 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-47 (l)-2 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-48 (l)-2 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-49 (l)-2 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-50 (l)-2 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-51 (l)-2 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-52 (l)-2 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-53 (l)-2 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-54 (l)-2 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-55 (l)-2 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-56 (l)-2 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-57 (l)-2 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-58 (l)-2 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-59 (l)-3 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-60 (l)-3 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-61 (l)-3 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-62 (l)-3 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-63 (l)-3 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-64 (l)-3 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-65 (l)-3 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-66 (l)-3 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-67 (l)-3 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-68 (l)-3 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-69 (l)-3 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-70 (l)-3 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-71 (l)-3 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-72 (l)-3 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-73 (l)-3 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-74 (l)-3 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-75 (l)-3 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-76 (l)-3 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-77 (l)-3 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-78 (l)-3 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-79 (l)-3 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-80 (l)-3 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-81 (l)-3 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-82 (l)-3 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-83 (l)-3 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-84 (l)-3 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-85 (l)-3 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-86 (l)-3 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-87 (l)-3 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-88 (l)-4 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-89 (l)-4 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-90 (l)-4 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-91 (l)-4 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-92 (l)-4 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-93 (l)-4 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-94 (l)-4 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-95 (l)-4 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-96 (l)-4 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-97 (l)-4 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-98 (l)-4 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-99 (l)-4 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-100 (l)-4 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-101 (l)-4 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-102 (l)-4 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-103 (l)-4 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-104 (l)-4 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-105 (l)-4 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-106 (l)-4 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-107 (l)-4 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-108 (l)-4 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-109 (l)-4 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-110 (l)-4 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-111 (l)-4 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-112 (l)-4 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-113 (l)-4 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-114 (l)-4 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-115 (l)-4 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-116 (l)-4 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-117 (l)-5 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-118 (l)-5 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-119 (l)-5 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-120 (l)-5 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-121 (l)-5 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-122 (l)-5 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-123 (l)-5 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-124 (l)-5 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-125 (l)-5 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-126 (l)-5 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-127 (l)-5 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-128 (l)-5 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-129 (l)-5 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-130 (l)-5 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-131 (l)-5 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-132 (l)-5 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-133 (l)-5 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-134 (l)-5 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-135 (l)-5 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-136 (l)-5 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-137 (l)-5 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-138 (l)-5 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-139 (l)-5 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-140 (l)-5 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-141 (l)-5 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-142 (l)-5 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-143 (l)-5 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-144 (l)-5 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-145 (l)-5 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-146 (l)-6 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-147 (l)-6 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-148 (l)-6 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-149 (l)-6 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-150 (l)-6 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-151 (l)-6 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-152 (l)-6 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-153 (l)-6 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-154 (l)-6 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-155 (l)-6 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-156 (l)-6 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-157 (l)-6 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-158 (l)-6 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-159 (l)-6 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-160 (l)-6 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-161 (l)-6 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-162 (l)-6 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-163 (l)-6 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-164 (l)-6 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-165 (l)-6 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-166 (l)-6 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-167 (l)-6 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-168 (l)-6 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-169 (l)-6 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-170 (l)-6 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-171 (l)-6 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-172 (l)-6 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-173 (l)-6 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-174 (l)-6 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-175 (l)-7 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-176 (l)-7 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-177 (l)-7 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-178 (l)-7 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-179 (l)-7 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-180 (l)-7 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-181 (l)-7 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-182 (l)-7 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-183 (l)-7 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-184 (l)-7 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-185 (l)-7 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-186 (l)-7 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-187 (l)-7 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-188 (l)-7 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-189 (l)-7 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-190 (l)-7 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-191 (l)-7 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-192 (l)-7 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-193 (l)-7 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-194 (l)-7 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-195 (l)-7 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-196 (l)-7 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-197 (l)-7 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-198 (l)-7 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-199 (l)-7 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-200 (l)-7 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-201 (l)-7 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-202 (l)-7 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-203 (l)-7 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-204 (l)-8 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-205 (l)-8 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-206 (l)-8 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-207 (l)-8 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-208 (l)-8 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-209 (l)-8 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-210 (l)-8 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-211 (l)-8 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-212 (l)-8 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-213 (l)-8 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-214 (l)-8 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-215 (l)-8 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B1-216 (l)-8 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-217 (l)-8 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-218 (l)-8 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-219 (l)-8 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-220 (l)-8 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-221 (l)-8 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-222 (l)-8 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-223 (l)-8 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-224 (l)-8 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-225 (l)-8 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-226 (l)-8 (ll)-23 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-227 (l)-8 (ll)-24 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-228 (l)-8 (ll)-25 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B 1-229 (l)-8 (ll)-26 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-230 (l)-8 (ll)-27 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-231 (l)-8 (ll)-28 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-232 (l)-8 (ll)-29 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-233 (l)-9 (ll)-1 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-234 (l)-9 (ll)-2 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-235 (l)-9 (ll)-3 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-236 (l)-9 (ll)-4 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-237 (l)-9 (ll)-5 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-238 (l)-9 (ll)-6 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-239 (l)-9 (ll)-7 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-240 (l)-9 (ll)-8 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-241 (l)-9 (ll)-9 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1:50
B 1-242 (l)-9 (ll)-10 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-243 (l)-9 (ll)-11 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-244 (l)-9 (ll)-12 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-245 (l)-9 (ll)-13 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-246 (l)-9 (ll)-14 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-247 (l)-9 (ll)-15 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-248 (l)-9 (ll)-16 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-249 (l)-9 (ll)-17 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-250 (l)-9 (ll)-18 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B1-251 (l)-9 (ll)-19 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-252 (l)-9 (ll)-20 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-253 (l)-9 (ll)-21 preferably 20:1 to 1:20, more preferably 10:1 to 1:10
50:1 to 1:50
B 1-254 (l)-9 (ll)-22 preferably 20:1 to 1:20, more preferably 10:1 to 1:10 component
compo¬
(1) (2) weight ratio (1) : (2) sition
50:1 to 1 :50
B 1 -255 (l)-9 (ll)-23 preferably 20:1 to 1 :20,
more preferably 10:1 to 1 :10
50:1 to 1 :50
B 1 -256 (l)-9 (ll)-24 preferably 20:1 to 1 :20,
more preferably 10:1 to 1 :10
50:1 to 1 :50
B 1 -257 (l)-9 (ll)-25 preferably 20:1 to 1 :20,
more preferably 10:1 to 1 :10
50:1 to 1 :50
B 1 -258 (l)-9 (ll)-26 preferably 20:1 to 1 :20,
more preferably 10:1 to 1 :10
50:1 to 1 :50
B 1 -259 (l)-9 (ll)-27 preferably 20:1 to 1 :20,
more preferably 10:1 to 1 :10
50:1 to 1 :50
B 1 -260 (l)-9 (ll)-28 preferably 20:1 to 1 :20,
more preferably 10:1 to 1 :10
50:1 to 1 :50
B1 -261 (l)-9 (ll)-29 preferably 20:1 to 1 :20,
more preferably 10:1 to 1 :10
The compositions according to the invention are suitable as fungicides. They are distinguished by an outstanding effectiveness against a broad spectrum of phytopatho- genic fungi, including soil-borne fungi, which derive especially from the classes of the Plasmodiophoromycetes, Peronosporomycetes (syn. Oomycetes), Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes and Deuteromycetes (syn. Fungi imper- fecti). Some are systemically effective and they can be used in crop protection as foliar fungicides, fungicides for seed dressing and soil fungicides. Moreover, they are suitable for controlling phytopathogenic fungi, which inter alia occur in wood or roots of plants.
The compositions according to the invention are particularly important in the control of a multitude of phytopathogenic fungi on various cultivated plants, such as cereals, e. g. wheat, rye, barley, triticale, oats or rice; beet, e. g. sugar beet or fodder beet; fruits, such as pomes, stone fruits or soft fruits, e. g. apples, pears, plums, peaches, almonds, cherries, strawberries, raspberries, blackberries or gooseberries; leguminous plants, such as lentils, peas, alfalfa or soybeans; oil plants, such as rape, mustard, olives, sunflowers, coconut, cocoa beans, castor oil plants, oil palms, ground nuts or soybeans; cucurbits, such as squashes, cucumber or melons; fiber plants, such as cotton, flax, hemp or jute; citrus fruit, such as oranges, lemons, grapefruits or mandarins; vegeta- bles, such as spinach, lettuce, asparagus, cabbages, carrots, onions, tomatoes, potatoes, cucurbits or paprika; lauraceous plants, such as avocados, cinnamon or camphor; energy and raw material plants, such as corn, soybean, rape, sugar cane or oil palm; corn; tobacco; nuts; coffee; tea; bananas; vines (table grapes and grape juice grape vines); hop; turf; sweet leaf (also called Stevia); natural rubber plants or ornamental and forestry plants, such as flowers, shrubs, broad-leaved trees or evergreens, e. g. conifers; and on the plant propagation material, such as seeds, and the crop material of these plants.
Preferably, the inventive compositions are used for controlling a multitude of fungi on field crops, such as potatoes sugar beets, tobacco, wheat, rye, barley, oats, rice, corn, cotton, soybeans, rape, legumes, sunflowers, coffee or sugar cane; fruits; vines; ornamentals; or vegetables, such as cucumbers, tomatoes, beans or squashes.
The term "plant propagation material" is to be understood to denote all the generative parts of the plant such as seeds and vegetative plant material such as cuttings and tubers (e. g. potatoes), which can be used for the multiplication of the plant. This includes seeds, roots, fruits, tubers, bulbs, rhizomes, shoots, sprouts and other parts of plants, including seedlings and young plants, which are to be transplanted after germination or after emergence from soil. These young plants may also be protected before transplantation by a total or partial treatment by immersion or pouring.
Preferably, treatment of plant propagation materials with compound (I) and compound (II) and/or a composition comprising said compounds, respectively, is used for controlling a multitude of fungi on cereals, such as wheat, rye, barley and oats; rice, corn, cotton and soybeans.
The term "cultivated plants" is to be understood as including plants which have been modified by breeding, mutagenesis or genetic engineering including but not limiting to agricultural biotech products on the market or in development (cf.
http://www.bio.org/speeches/pubs/er/agri_products.asp). Genetically modified plants are plants, which genetic material has been so modified by the use of recombinant DNA techniques that under natural circumstances cannot readily be obtained by cross breeding, mutations or natural recombination. Typically, one or more genes have been integrated into the genetic material of a genetically modified plant in order to improve certain properties of the plant. Such genetic modifications also include but are not limited to targeted post-translational modification of protein(s), oligo- or polypeptides e. g. by glycosylation or polymer additions such as prenylated, acetylated or farnesylated moieties or PEG moieties.
Plants that have been modified by breeding, mutagenesis or genetic engineering, e. g. have been rendered tolerant to applications of specific classes of herbicides, such as auxin herbicides such as dicamba or 2,4-D; bleacher herbicides such as hydroxyl- phenylpyruvate dioxygenase (HPPD) inhibitors or phytoene desaturase (PDS) inhibit- tors; acetolactate synthase (ALS) inhibitors such as sulfonyl ureas or imidazolinones; enolpyruvylshikimate-3-phosphate synthase (EPSPS) inhibitors, such as glyphosate; glutamine synthetase (GS) inhibitors such as glufosinate; protoporphyrinogen-IX oxidase inhibitors; lipid biosynthesis inhibitors such as acetyl CoA carboxylase (ACCase) inhibitors; or oxynil (i. e. bromoxynil or ioxynil) herbicides as a result of conventional methods of breeding or genetic engineering. Furthermore, plants have been made resistant to multiple classes of herbicides through multiple genetic modifications, such as resistance to both glyphosate and glufosinate or to both glyphosate and a herbicide from another class such as ALS inhibitors, HPPD inhibitors, auxin herbicides, or AC- Case inhibitors. These herbicide resistance technologies are e. g. described in Pest Managem. Sci. 61 , 2005, 246; 61 , 2005, 258; 61 , 2005, 277; 61 , 2005, 269; 61 , 2005, 286; 64, 2008, 326; 64, 2008, 332; Weed Sci. 57, 2009, 108; Austral. J. Agricult. Res. 58, 2007, 708; Science 316, 2007, 1 185; and references quoted therein. Several culti- vated plants have been rendered tolerant to herbicides by conventional methods of breeding (mutagenesis), e. g. Clearfield® summer rape (Canola, BASF SE, Germany) being tolerant to imidazolinones, e. g. imazamox, or ExpressSun® sunflowers (DuPont, USA) being tolerant to sulfonyl ureas, e. g. tribenuron. Genetic engineering methods have been used to render cultivated plants such as soybean, cotton, corn, beets and rape, tolerant to herbicides such as glyphosate and glufosinate, some of which are commercially available under the trade names RoundupReady® (glyphosate-tolerant, Monsanto, U.S.A.), Cultivance® (imidazolinone tolerant, BASF SE, Germany) and Lib- ertyLink® (glufosinate-tolerant, Bayer CropScience, Germany).
Furthermore, plants are also covered that are by the use of recombinant DNA tech- niques capable to synthesize one or more insecticidal proteins, especially those known from the bacterial genus Bacillus, particularly from Bacillus thuringiensis, such as δ- endotoxins, e. g. CrylA(b), CrylA(c), CrylF, CrylF(a2), CryllA(b), CrylllA, CrylllB(bl ) or Cry9c; vegetative insecticidal proteins (VIP), e. g. VIP1 , VIP2, VIP3 or VIP3A; insecticidal proteins of bacteria colonizing nematodes, e. g. Photorhabdus spp. or Xenorhab- dus spp.; toxins produced by animals, such as scorpion toxins, arachnid toxins, wasp toxins, or other insect-specific neurotoxins; toxins produced by fungi, such Streptomy- cetes toxins, plant lectins, such as pea or barley lectins; agglutinins; proteinase inhibitors, such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin or papain inhibitors; ribosome-inactivating proteins (RIP), such as ricin, maize-RIP, abrin, luffin, saporin or bryodin; steroid metabolism enzymes, such as 3-hydroxysteroid oxidase, ecdysteroid-IDP-glycosyl-transferase, cholesterol oxidases, ecdysone inhibitors or HMG-CoA-reductase; ion channel blockers, such as blockers of sodium or calcium channels; juvenile hormone esterase; diuretic hormone receptors (helicokinin receptors); stilben synthase, bibenzyl synthase, chitinases or glucanases. In the context of the present invention these insecticidal proteins or toxins are to be understood expressly also as pre-toxins, hybrid proteins, truncated or otherwise modified proteins. Hybrid proteins are characterized by a new combination of protein domains, (see, e. g. WO 02/015701 ). Further examples of such toxins or genetically modified plants capable of synthesizing such toxins are disclosed, e. g., in EP-A 374 753, WO 93/007278, WO 95/34656, EP-A 427 529, EP-A 451 878, WO 03/18810 und WO 03/52073. The methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e. g. in the publications mentioned above. These insecticidal proteins contained in the genetically modified plants impart to the plants producing these proteins tolerance to harmful pests from all taxonomic groups of athropods, especially to beetles (Coeloptera), two-winged insects (Diptera), and moths (Lepidoptera) and to nematodes (Nematoda). Genetically modified plants capable to synthesize one or more insecticidal proteins are, e. g., described in the publications mentioned above, and some of which are commercially available such as YieldGard® (corn cultivars producing the CrylAb toxin), YieldGard® Plus (corn cultivars producing CrylAb and Cry3Bb1 toxins), Starlink® (corn cultivars producing the Cry9c toxin), Her- culex® RW (corn cultivars producing Cry34Ab1 , Cry35Ab1 and the enzyme Phosphi- nothricin-N-Acetyltransferase [PAT]); NuCOTN® 33B (cotton cultivars producing the CrylAc toxin), Bollgard® I (cotton cultivars producing the CrylAc toxin), Bollgard® II (cotton cultivars producing CrylAc and Cry2Ab2 toxins); VIPCOT® (cotton cultivars producing a VIP-toxin); NewLeaf® (potato cultivars producing the Cry3A toxin); Bt- Xtra®, NatureGard®, KnockOut®, BiteGard®, Protecta®, Bt1 1 (e. g. Agrisure® CB) and Bt176 from Syngenta Seeds SAS, France, (corn cultivars producing the CrylAb toxin and PAT enyzme), MIR604 from Syngenta Seeds SAS, France (corn cultivars producing a modified version of the Cry3A toxin, c.f. WO 03/018810), MON 863 from Monsanto Europe S.A., Belgium (corn cultivars producing the Cry3Bb1 toxin), IPC 531 from Monsanto Europe S.A., Belgium (cotton cultivars producing a modified version of the CrylAc toxin) and 1507 from Pioneer Overseas Corporation, Belgium (corn cultivars producing the Cry1 F toxin and PAT enzyme).
Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the resistance or tolerance of those plants to bacterial, viral or fungal pathogens. Examples of such proteins are the so-called "pathogenesis-related proteins" (PR proteins, see, e. g.
EP-A 392 225), plant disease resistance genes (e. g. potato cultivars, which express resistance genes acting against Phytophthora infestans derived from the mexican wild potato Solanum bulbocastanum) or T4-lysozym (e. g. potato cultivars capable of synthesizing these proteins with increased resistance against bacteria such as Erwinia amylvora). The methods for producing such genetically modified plants are generally known to the person skilled in the art and are described, e. g. in the publications mentioned above.
Furthermore, plants are also covered that are by the use of recombinant DNA techniques capable to synthesize one or more proteins to increase the productivity (e. g. bio mass production, grain yield, starch content, oil content or protein content), toler- ance to drought, salinity or other growth-limiting environmental factors or tolerance to pests and fungal, bacterial or viral pathogens of those plants.
Furthermore, plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve human or animal nutrition, e. g. oil crops that produce health- promoting long-chain omega-3 fatty acids or unsaturated omega-9 fatty acids (e. g. Nexera® rape, DOW Agro Sciences, Canada).
Furthermore, plants are also covered that contain by the use of recombinant DNA techniques a modified amount of substances of content or new substances of content, specifically to improve raw material production, e. g. potatoes that produce increased amounts of amylopectin (e. g. Amflora® potato, BASF SE, Germany).
The inventive compositions are particularly suitable for controlling the following plant diseases:
Albugo spp. (white rust) on ornamentals, vegetables (e. g. A. Candida) and sunflowers (e. g. A. tragopogonis); Alternaria spp. (Alternaria leaf spot) on vegetables, rape (A. brassicola or brassicae), sugar beets (A. tenuis), fruits, rice, soybeans, potatoes (e. g. A. solani or A. alternata), tomatoes (e. g. A. solani or A. alternata) and wheat; Aphano- myces spp. on sugar beets and vegetables; Ascochyta spp. on cereals and vegetables, e. g. A. tritici (anthracnose) on wheat and A. hordei on barley; Bipolaris and Drechslera spp. (teleomorph: Cochliobolus spp.), e. g. Southern leaf blight (D. maydis) or Northern leaf blight (B. zeicola) on corn, e. g. spot blotch (B. sorokiniana) on cereals and e.g. B. oryzae on rice and turfs; Blumeria (formerly Erysiphe) graminis (powdery mildew) on cereals (e. g. on wheat or barley); Botrytis cinerea (teleomorph: Botryotinia fuckeliana: grey mold) on fruits and berries (e. g. strawberries), vegetables (e. g. lettuce, carrots, celery and cabbages), rape, flowers, vines, forestry plants and wheat; Bremia lactucae (downy mildew) on lettuce; Ceratocystis (syn. Ophiostoma) spp. (rot or wilt) on broad- leaved trees and evergreens, e. g. C. ulmi (Dutch elm disease) on elms; Cercospora spp. (Cercospora leaf spots) on corn (e.g. Gray leaf spot: C. zeae-maydis), rice, sugar beets (e. g. C. beticola), sugar cane, vegetables, coffee, soybeans (e. g. C. sojina or C. kikuchii) and rice; Cladosporium spp. on tomatoes (e. g. C. fulvum: leaf mold) and cereals, e. g. C. herbarum (black ear) on wheat; Claviceps purpurea (ergot) on cereals; Cochliobolus (anamorph: Helminthosporium of Bipolaris) spp. (leaf spots) on corn (C. carbonum), cereals (e. g. C. sativus, anamorph: B. sorokiniana) and rice (e. g. C. miy- abeanus, anamorph: H. oryzae); Colletotrichum (teleomorph: Glomerella) spp. (anthracnose) on cotton (e. g. C. gossypii), corn (e. g. C. graminicola: Anthracnose stalk rot), soft fruits, potatoes (e. g. C. coccodes: black dot), beans (e. g. C. Iindemuthianum) and soybeans (e. g. C. truncatum or C. gloeosporioides); Corticium spp., e. g. C. sa- sakii (sheath blight) on rice; Corynespora cassiicola (leaf spots) on soybeans and or- namentals; Cycloconium spp., e. g. C. oleaginum on olive trees; Cylindrocarpon spp. (e. g. fruit tree canker or young vine decline, teleomorph: Nectria or Neonectria spp.) on fruit trees, vines (e. g. C. liriodendri, teleomorph: Neonectria liriodendri: Black Foot Disease) and ornamentals; Dematophora (teleomorph: Rosellinia) necatrix (root and stem rot) on soybeans; Diaporthe spp., e. g. D. phaseolorum (damping off) on soy- beans; Drechslera (syn. Helminthosporium, teleomorph: Pyrenophora) spp. on corn, cereals, such as barley (e. g. D. teres, net blotch) and wheat (e. g. D. tritici-repentis: tan spot), rice and turf; Esca (dieback, apoplexy) on vines, caused by Formitiporia (syn. Phellinus) punctata, F. mediterranea, Phaeomoniella chlamydospora (earlier Phaeo- acremonium chlamydosporum), Phaeoacremonium aleophilum and/or Botryosphaeria obtusa; Elsinoe spp. on pome fruits (E. pyri), soft fruits (E. veneta: anthracnose) and vines (E. ampelina: anthracnose); Entyloma oryzae (leaf smut) on rice; Epicoccum spp. (black mold) on wheat; Erysiphe spp. (powdery mildew) on sugar beets (E. betae), vegetables (e. g. E. pisi), such as cucurbits (e. g. E. cichoracearum), cabbages, rape (e. g. E. cruciferarum); Eutypa lata (Eutypa canker or dieback, anamorph: Cytosporina lata, syn. Libertella blepharis) on fruit trees, vines and ornamental woods; Exserohilum (syn. Helminthosporium) spp. on corn (e. g. E. turcicum); Fusarium (teleomorph: Gib- berella) spp. (wilt, root or stem rot) on various plants, such as F. graminearum or F. culmorum (root rot, scab or head blight) on cereals (e. g. wheat or barley), F. oxy- sporum on tomatoes, F. solani on soybeans and F. verticillioides on corn; Gaeumanno- myces graminis (take-all) on cereals (e. g. wheat or barley) and corn; Gibberella spp. on cereals (e. g. G. zeae) and rice (e. g. G. fujikuroi: Bakanae disease); Glomerella cingulata on vines, pome fruits and other plants and G. gossypii on cotton; Grain- staining complex on rice; Guignardia bidwellii (black rot) on vines; Gymnosporangium spp. on rosaceous plants and junipers, e. g. G. sabinae (rust) on pears; Helminthosporium spp. (syn. Drechslera, teleomorph: Cochliobolus) on corn, cereals and rice; Hemileia spp., e. g. H. vastatrix (coffee leaf rust) on coffee; Isariopsis clavispora (syn. Cladosporium vitis) on vines; Macrophomina phaseolina (syn. phaseoli) (root and stem rot) on soybeans and cotton; Microdochium (syn. Fusarium) nivale (pink snow mold) on cereals (e. g. wheat or barley); Microsphaera diffusa (powdery mildew) on soybeans; Monilinia spp., e. g. M. laxa, M. fructicola and M. fructigena (bloom and twig blight, brown rot) on stone fruits and other rosaceous plants; Mycosphaerella spp. on cereals, bananas, soft fruits and ground nuts, such as e. g. M. graminicola (anamorph: Septoria tritici, Septoria blotch) on wheat or M. fijiensis (black Sigatoka disease) on bananas; Peronospora spp. (downy mildew) on cabbage (e. g. P. brassicae), rape (e. g. P. parasitica), onions (e. g. P. destructor), tobacco (P. tabacina) and soybeans (e. g. P.
manshurica); Phakopsora pachyrhizi and P. meibomiae (soybean rust) on soybeans; Phialophora spp. e. g. on vines (e. g. P. tracheiphila and P. tetraspora) and soybeans (e. g. P. gregata: stem rot); Phoma lingam (root and stem rot) on rape and cabbage and P. betae (root rot, leaf spot and damping-off) on sugar beets; Phomopsis spp. on sunflowers, vines (e. g. P. viticola: can and leaf spot) and soybeans (e. g. stem rot: P. phaseoli, teleomorph: Diaporthe phaseolorum); Physoderma maydis (brown spots) on corn; Phytophthora spp. (wilt, root, leaf, fruit and stem root) on various plants, such as paprika and cucurbits (e. g. P. capsici), soybeans (e. g. P. megasperma, syn. P. sojae), potatoes and tomatoes (e. g. P. infestans: late blight) and broad-leaved trees (e. g. P. ramorum: sudden oak death); Plasmodiophora brassicae (club root) on cabbage, rape, radish and other plants; Plasmopara spp., e. g. P. viticola (grapevine downy mildew) on vines and P. halstedii on sunflowers; Podosphaera spp. (powdery mildew) on rosa- ceous plants, hop, pome and soft fruits, e. g. P. leucotricha on apples; Polymyxa spp., e. g. on cereals, such as barley and wheat (P. graminis) and sugar beets (P. betae) and thereby transmitted viral diseases; Pseudocercosporella herpotrichoides (eyespot, teleomorph: Tapesia yallundae) on cereals, e. g. wheat or barley; Pseudoperonospora (downy mildew) on various plants, e. g. P. cubensis on cucurbits or P. humili on hop; Pseudopezicula tracheiphila (red fire disease or .rotbrenner', anamorph: Phialophora) on vines; Puccinia spp. (rusts) on various plants, e. g. P. triticina (brown or leaf rust), P. striiformis (stripe or yellow rust), P. hordei (dwarf rust), P. graminis (stem or black rust) or P. recondita (brown or leaf rust) on cereals, such as e. g. wheat, barley or rye, P. kuehnii (orange rust) on sugar cane and P. asparagi on asparagus; Pyrenophora (anamorph: Drechslera) tritici-repentis (tan spot) on wheat or P. teres (net blotch) on barley; Pyricularia spp., e. g. P. oryzae (teleomorph: Magnaporthe grisea, rice blast) on rice and P. grisea on turf and cereals; Pythium spp. (damping-off) on turf, rice, corn, wheat, cotton, rape, sunflowers, soybeans, sugar beets, vegetables and various other plants (e. g. P. ultimum or P. aphanidermatum); Ramularia spp., e. g. R. collo-cygni (Ramularia leaf spots, Physiological leaf spots) on barley and R. beticola on sugar beets; Rhizoctonia spp. on cotton, rice, potatoes, turf, corn, rape, potatoes, sugar beets, vegetables and various other plants, e. g. R. solani (root and stem rot) on soy- beans, R. solani (sheath blight) on rice or R. cerealis (Rhizoctonia spring blight) on wheat or barley; Rhizopus stolonifer (black mold, soft rot) on strawberries, carrots, cabbage, vines and tomatoes; Rhynchosporium secalis (scald) on barley, rye and triti- cale; Sarocladium oryzae and S. attenuatum (sheath rot) on rice; Sclerotinia spp. (stem rot or white mold) on vegetables and field crops, such as rape, sunflowers (e. g. S. sclerotiorum) and soybeans (e. g. S. rolfsii or S. sclerotiorum); Septoria spp. on various plants, e. g. S. glycines (brown spot) on soybeans, S. tritici (Septoria blotch) on wheat and S. (syn. Stagonospora) nodorum (Stagonospora blotch) on cereals; Uncinula (syn. Erysiphe) necator (powdery mildew, anamorph: Oidium tuckeri) on vines; Setospaeria spp. (leaf blight) on corn (e. g. S. turcicum, syn. Helminthosporium turcicum) and turf; Sphacelotheca spp. (smut) on corn, (e. g. S. reiliana: head smut), sorghum und sugar cane; Sphaerotheca fuliginea (powdery mildew) on cucurbits; Spongospora subterra- nea (powdery scab) on potatoes and thereby transmitted viral diseases; Stagonospora spp. on cereals, e. g. S. nodorum (Stagonospora blotch, teleomorph: Leptosphaeria [syn. Phaeosphaeria] nodorum) on wheat; Synchytrium endobioticum on potatoes (po- tato wart disease); Taphrina spp., e. g. T. deformans (leaf curl disease) on peaches and T. pruni (plum pocket) on plums; Thielaviopsis spp. (black root rot) on tobacco, pome fruits, vegetables, soybeans and cotton, e. g. T. basicola (syn. Chalara elegans); Tilletia spp. (common bunt or stinking smut) on cereals, such as e. g. T. tritici (syn. T. caries, wheat bunt) and T. controversa (dwarf bunt) on wheat; Typhula incarnata (grey snow mold) on barley or wheat; Urocystis spp., e. g. U. occulta (stem smut) on rye; Uromyces spp. (rust) on vegetables, such as beans (e. g. U. appendiculatus, syn. U. phaseoli) and sugar beets (e. g. U. betae); Ustilago spp. (loose smut) on cereals (e. g. U. nuda and U. avaenae), corn (e. g. U. maydis: corn smut) and sugar cane; Venturia spp. (scab) on apples (e. g. V. inaequalis) and pears; and Verticillium spp. (wilt) on various plants, such as fruits and ornamentals, vines, soft fruits, vegetables and field crops, e. g. V. dahliae on strawberries, rape, potatoes and tomatoes.
The inventive compositions are also suitable for controlling phytopathogenic fungi in the protection of stored products or harvest and in the protection of materials. The term "protection of materials" is to be understood to denote the protection of technical and non-living materials, such as adhesives, glues, wood, paper and paperboard, textiles, leather, paint dispersions, plastics, colling lubricants, fiber or fabrics, against the infestation and destruction by harmful microorganisms, such as fungi and bacteria. As to the protection of wood and other materials, the particular attention is paid to the following phytopathogenic fungi: Ascomycetes such as Ophiostoma spp., Ceratocystis spp., Aureobasidium pullulans, Sclerophoma spp., Chaetomium spp., Humicola spp., Petriella spp., Trichurus spp.; Basidiomycetes such as Coniophora spp., Coriolus spp., Gloeophyllum spp., Lentinus spp., Pleurotus spp., Poria spp., Serpula spp. and Tyro- myces spp., Deuteromycetes such as Aspergillus spp., Cladosporium spp., Penicillium spp., Trichorma spp., Alternaria spp., Paecilomyces spp. and Zygomycetes such as Mucor spp., and in addition in the protection of stored products and harvest the following yeast fungi are worthy of note: Candida spp. and Saccharomyces cerevisae. According to one specific embodiment, the compositions of the invention are especially suitable in the control of Plasmopara spp., for example P. viticola.
According to a further specific embodiment, the compositions of the invention are especially suitable in the control of Phytophthora spp., for example P. infestans: late blight.
According to still a further specific embodiment, the compositions of the invention are especially suitable in the control of Peronospora spp. (downy mildew), for eample P. brassicae and P. destructor.
According to still a further specific embodiment, the compositions of the invention are especially suitable in the control of leaf spots in various cultivated plants, for example Alternaria spp. (Alternaria leaf spot) A. solani or A. alternata, A. brassicola or brassica- e.
According to still a further specific embodiment, the compositions of the invention are especially suitable in the control of Pseudoperonospora (downy mildew) on various plants.
According to one specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on vines (table grapes and grape juice grape vines).
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on potatoes.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on rapeseed (in particular canola, oilseed-rape).
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on beans.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on artichoke.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on asparagus.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on beetroot.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on broccoli. According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on brussels sprouts.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on cabbage.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on cauliflower.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on celery.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on chicory.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on chives.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on cress.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on cucumbers.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on eggplant.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on endive and chicory.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on fennel.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on garlic.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on gourd.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on kohlrabi.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on lettuce.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on leeks.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on melon.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on onion.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on parsley.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on peas.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on pepper.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on punpkin.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on radish.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on rhubarb.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on shallot.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on spinach.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on tomato.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on watermelon.
According to another specific embodiment, the compositions of the invention are especially suitable in the control of phytopathogenic fungi on zucchini.
According to a preferred embodiment, the inventive compositions are used for controlling a multitude of fungi on field crops, such as potatoes, rape, legumes; fruits; vines; or vegetables, such as cucumbers, tomatoes, beans or squashes.
Preferred cultivated plants that can be protected and/or cured according to the present invention are vines, potatoes, rapeseed, in particular canola, oilseed-rape, beans, cucumbers, melon, peas, spinach, tomato and watermelon. The inventive compositions may also be used for improving the health of a plant. The invention also relates to a method for improving plant health by treating a plant, its propagation material and/or the locus where the plant is growing or is to grow with an effective amount of an inventive composition.
The term "plant health" is to be understood to denote a condition of the plant and/or its products which is determined by several indicators alone or in combination with each other such as yield (e. g. increased biomass and/or increased content of valuable ingredients), plant vigor (e. g. improved plant growth and/or greener leaves ("greening effect")), quality (e. g. improved content or composition of certain ingredients) and tolerance to abiotic and/or biotic stress. The above identified indicators for the health con- dition of a plant may be interdependent or may result from each other.
The compounds (I) and/or (II) can be present in different crystal modifications whose biological activity may differ. Compositions comprising said modifications are likewise subject matter of the present invention.
The application of the inventive compositions can be carried out both before and af- ter the infection of the plants, plant propagation materials, such as seeds, soil, surfaces, materials or rooms by the fungi.
Plant propagation materials may be treated with the inventive compositions prophy- lactically either at or before planting or transplanting. The invention also relates to agrochemical compositions comprising a solvent or solid carrier and at least one composition of the invention and to the use for controlling phytopathogenic fungi.
An agrochemical composition comprises a fungicidally effective amount of an inven- tive composition. The term "fungicidally effective amount" denotes an amount of the composition, which is sufficient for controlling phytopathogenic fungi on cultivated plants or in the protection of materials and which does not result in a substantial damage to the treated plants. Such an amount can vary in a broad range and is dependent on various factors, such as the fungal species to be controlled, the treated cultivated plant or material, the climatic conditions and the specific composition used.
The inventive compositions, comprising a compound (I) and/or a N-oxide or salt thereof and a compound (II) and/or a N-oxide or salt thereof can be converted into customary types of agrochemical compositions, e. g. solutions, emulsions, suspensions, dusts, powders, pastes and granules. The composition type depends on the particular intended purpose; in each case, it should ensure a fine and uniform distribution of the components used according to the invention.
Examples for composition types are suspensions (SC, OD, FS), emulsifiable concentrates (EC), emulsions (EW, EO, ES), pastes, pastilles, wettable powders or dusts (WP, SP, SS, WS, DP, DS) or granules (GR, FG, GG, MG), which can be water- soluble or wettable, as well as gel formulations for the treatment of plant propagation materials such as seeds (GF).
Usually the composition types (e. g. SC, OD, FS, EC, WG, SG, WP, SP, SS, WS, GF) are employed diluted. Composition types such as DP, DS, GR, FG, GG and MG are usually used undiluted.
The compositions are prepared in a known manner (cf. US 3,060,084,
EP-A 707 445 (for liquid concentrates), Browning: "Agglomeration", Chemical Engineering, Dec. 4, 1967, 147-48, Perry's Chemical Engineer's Handbook, 4th Ed., McGraw-Hill, New York, 1963, S. 8-57 und ff. WO 91/13546, US 4,172,714,
US 4,144,050, US 3,920,442, US 5,180,587, US 5,232,701 , US 5,208,030,
GB 2,095,558, US 3,299,566, Klingman: Weed Control as a Science (J. Wiley & Sons, New York, 1961 ), Hance et al.: Weed Control Handbook (8th Ed., Blackwell Scientific, Oxford, 1989) and Mollet, H. and Grubemann, A.: Formulation technology (Wiley VCH Verlag, Weinheim, 2001 ).
The agrochemical compositions may also comprise auxiliaries which are customary in agrochemical compositions. The auxiliaries used depend on the particular application form and active substances, respectively.
Examples for suitable auxiliaries are solvents, solid carriers, dispersants or emulsi- fiers (such as further solubilizers, protective colloids, surfactants and adhesion agents), organic and anorganic thickeners, bactericides, anti-freezing agents, anti-foaming agents, if appropriate colorants and tackifiers or binders (e. g. for seed treatment formulations).
Suitable solvents are water, organic solvents such as mineral oil fractions of medium to high boiling point, such as kerosene or diesel oil, furthermore coal tar oils and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons, e. g. toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalenes or their derivatives, alcohols such as methanol, ethanol, propanol, butanol and cyclohexanol, glycols, ketones such as cyclohexanone and gamma-butyrolactone, fatty acid dimethyla- mides, fatty acids and fatty acid esters and strongly polar solvents, e. g. amines such as N-methylpyrrolidone.
Solid carriers are mineral earths such as silicates, silica gels, talc, kaolins, limestone, lime, chalk, bole, loess, clays, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers, such as, e. g., ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and products of vegetable origin, such as cereal meal, tree bark meal, wood meal and nutshell meal, cellulose powders and other solid carriers.
Suitable surfactants (adjuvants, wtters, tackifiers, dispersants or emulsifiers) are alkali metal, alkaline earth metal and ammonium salts of aromatic sulfonic acids, such as ligninsoulfonic acid (Borresperse® types, Borregard, Norway) phenolsulfonic acid, naphthalenesulfonic acid (Morwet® types, Akzo Nobel, U.S.A.), dibutylnaphthalene- sulfonic acid (Nekal® types, BASF, Germany), and fatty acids, alkylsulfonates, alkyl- arylsulfonates, alkyl sulfates, laurylether sulfates, fatty alcohol sulfates, and sulfated hexa-, hepta- and octadecanolates, sulfated fatty alcohol glycol ethers, furthermore condensates of naphthalene or of naphthalenesulfonic acid with phenol and formaldehyde, polyoxy-ethylene octylphenyl ether, ethoxylated isooctylphenol, octylphenol, nonylphenol, alkylphenyl polyglycol ethers, tributylphenyl polyglycol ether, tristearyl- phenyl polyglycol ether, alkylaryl polyether alcohols, alcohol and fatty alcohol/ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether acetal, sorbitol esters, lignin-sulfite waste liquors and proteins, denatured proteins, polysaccharides (e. g. methylcellulose), hydrophobically modified starches, polyvinyl alcohols (Mowiol® types, Clariant, Switzerland), polycarboxylates (Sokolan® types, BASF, Germany), polyalkoxylates, polyvinyl- amines (Lupasol® types, BASF, Germany), polyvinylpyrrolidone and the copolymers therof.
Examples for thickeners (i. e. compounds that impart a modified flowability to compositions, i. e. high viscosity under static conditions and low viscosity during agitation) are polysaccharides and organic and anorganic clays such as Xanthan gum (Kelzan®, CP Kelco, U.S.A.), Rhodopol® 23 (Rhodia, France), Veegum® (R.T. Vanderbilt, U.S.A.) or Attaclay® (Engelhard Corp., NJ, USA).
Bactericides may be added for preservation and stabilization of the composition. Examples for suitable bactericides are those based on dichlorophene and benzyl- alcohol hemi formal (Proxel® from ICI or Acticide® RS from Thor Chemie and Kathon® MK from Rohm & Haas) and isothiazolinone derivatives such as alkylisothiazolinones and benzisothiazolinones (Acticide® MBS from Thor Chemie).
Examples for suitable anti-freezing agents are ethylene glycol, propylene glycol, urea and glycerin.
Examples for anti-foaming agents are silicone emulsions (such as e. g. Silikon® SRE, Wacker, Germany or Rhodorsil®, Rhodia, France), long chain alcohols, fatty acids, salts of fatty acids, fluoroorganic compounds and mixtures thereof.
Suitable colorants are pigments of low water solubility and water-soluble dyes. Examples to be mentioned are rhodamin B, C. I. pigment red 1 12, C. I. solvent red 1 , pigment blue 15:4, pigment blue 15:3, pigment blue 15:2, pigment blue 15:1 , pigment blue 80, pigment yellow 1 , pigment yellow 13, pigment red 1 12, pigment red 48:2, pigment red 48:1 , pigment red 57:1 , pigment red 53:1 , pigment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment green 7, pigment white 6, pigment brown 25, basic violet 10, basic violet 49, acid red 51 , acid red 52, acid red 14, acid blue 9, acid yellow 23, basic red 10, basic red 108.
Examples for tackifiers or binders are polyvinylpyrrolidone, polyvinylacetates, polyvinyl alcohols and cellulose ethers (Tylose®, Shin-Etsu, Japan).
Powders, materials for spreading and dusts can be prepared by mixing or concomitantly grinding the active compounds with at least one solid carrier.
Granules, e. g. coated granules, impregnated granules and homogeneous granules, can be prepared by binding the active substances to solid carriers. Examples of solid carriers are mineral earths such as silica gels, silicates, talc, kaolin, attaclay, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground synthetic materials, fertilizers, such as, e. g., ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas, and products of vegetable origin, such as cereal meal, tree bark meal, wood meal and nutshell meal, cellulose powders and other solid carriers.
Examples for composition types are:
1 . Composition types for dilution with water
i) Water-soluble concentrates (SL, LS)
10 parts by weight of a composition according to the invention are dissolved in 90 parts by weight of water or in a water-soluble solvent. As an alternative, wetting agents or other auxiliaries are added. The active substances dissolve upon dilution with water. In this way, a composition having a content of 10% by weight of active substances is obtained.
ii) Dispersible concentrates (DC)
20 parts by weight of a composition according to the invention are dissolved in 70 parts by weight of cyclohexanone with addition of 10 parts by weight of a dispersant, e. g. polyvinylpyrrolidone. Dilution with water gives a dispersion. The active substances content is 20% by weight.
iii) Emulsifiable concentrates (EC)
15 parts by weight of a composition according to the invention are dissolved in 75 parts by weight of xylene with addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (in each case 5 parts by weight). Dilution with water gives an emulsion. The composition has an active substances content of 15% by weight.
iv) Emulsions (EW, EO, ES)
25 parts by weight of a composition according to the invention are dissolved in 35 parts by weight of xylene with addition of calcium dodecylbenzenesulfonate and castor oil ethoxylate (in each case 5 parts by weight). This mixture is introduced into 30 parts by weight of water by means of an emulsifying machine (Ultraturrax) and made into a homogeneous emulsion. Dilution with water gives an emulsion. The composition has an active substances content of 25% by weight.
v) Suspensions (SC, OD, FS)
In an agitated ball mill, 20 parts by weight of a composition according to the invention are comminuted with addition of 10 parts by weight of dispersants and wetting agents and 70 parts by weight of water or an organic solvent to give a fine active sub- stances suspension. Dilution with water gives a stable suspension of the active composition. The active substances content in the composition is 20% by weight.
vi) Water-dispersible granules and water-soluble granules (WG, SG)
50 parts by weight of a composition according to the invention are ground finely with addition of 50 parts by weight of dispersants and wetting agents and prepared as wa- ter-dispersible or water-soluble granules by means of technical appliances (e. g. extrusion, spray tower, fluidized bed). Dilution with water gives a stable dispersion or solution of the active substances. The composition has an active substances content of 50% by weight.
vii) Water-dispersible powders and water-soluble powders (WP, SP, SS, WS) 75 parts by weight of a composition according to the invention are ground in a rotor- stator mill with addition of 25 parts by weight of dispersants, wetting agents and silica gel. Dilution with water gives a stable dispersion or solution of the active substances. The active substances content of the composition is 75% by weight.
viii) Gel (GF)
In an agitated ball mill, 20 parts by weight of a composition according to the invention are comminuted with addition of 10 parts by weight of dispersants, 1 part by weight of a gelling agent wetters and 70 parts by weight of water or of an organic solvent to give a fine suspension of the active substances. Dilution with water gives a stable suspension of the active substances, whereby a composition with 20% (w/w) of active substances is obtained.
2. Composition types to be applied undiluted
ix) Dustable powders (DP, DS)
5 parts by weight of a composition according to the invention are ground finely and mixed intimately with 95 parts by weight of finely divided kaolin. This gives a dustable composition having an active substances content of 5% by weight.
x) Granules (GR, FG, GG, MG)
0.5 parts by weight of a composition according to the invention is ground finely and associated with 99.5 parts by weight of carriers. Current methods are extrusion, spray- drying or the fluidized bed. This gives granules to be applied undiluted having an active substances content of 0.5% by weight.
xi) ULV solutions (UL)
10 parts by weight of a composition according to the invention are dissolved in 90 parts by weight of an organic solvent, e. g. xylene. This gives a composition to be ap- plied undiluted having an active substances content of 10% by weight.
The agrochemical compositions generally comprise between 0.01 and 95%, preferably between 0.1 and 90%, most preferably between 0.5 and 90%, by weight of ac- tive substances. The active substances are usually employed in a purity of from 90% to 100%, preferably from 95% to 100% (according to NMR spectrum).
Water-soluble concentrates (LS), flowable concentrates (FS), powders for dry treatment (DS), water-dispersible powders for slurry treatment (WS), water-soluble powders (SS), emulsions (ES) emulsifiable concentrates (EC) and gels (GF) are usu- ally employed for the purposes of treatment of plant propagation materials, particularly seeds. These compositions can be applied to plant propagation materials, particularly seeds, diluted or undiluted. The compositions in question give, after two-to-tenfold dilution, active substances concentrations of from 0.01 to 60% by weight, preferably from 0.1 to 40% by weight, in the ready-to-use preparations. Application can be carried out before or during sowing. Methods for applying the compounds of the inventive compositions on to plant propagation material, especially seeds, are known in the art, and include dressing, coating, pelleting, dusting, soaking and in-furrow application methods of the propagation material. In a preferred embodiment, the compounds of the inventive compositions are applied on to the plant propagation material by a method such that germination is not induced, e. g. by seed dressing, pelleting, coating and dusting.
In a preferred embodiment, a suspension-type (FS) composition is used for seed treatment. Typically, a FS composition may comprise 1 -800 g/l of active substances, 1 -200 g/l Surfactant, 0 to 200 g/l antifreezing agent, 0 to 400 g/l of binder, 0 to 200 g/l of a pigment and up to 1 liter of a solvent, preferably water.
The active substances of the inventive compositions can be used as such or in the form e. g. directly sprayable solutions, powders, suspensions, dispersions, emulsions, oil dispersions, pastes, dustable products, materials for spreading, or granules, by means of spraying, atomizing, dusting, spreading, brushing, immersing or pouring. The application forms depend entirely on the intended purposes; it is intended to ensure in each case the finest possible distribution of the active substances used according to the invention.
Aqueous application forms can be prepared from emulsion concentrates, pastes or wettable powders (sprayable powders, oil dispersions) by adding water. To prepare emulsions, pastes or oil dispersions, the substances, as such or dissolved in an oil or solvent, can be homogenized in water by means of a wetter, tackifier, dispersant or emulsifier. Alternatively, it is possible to prepare concentrates composed of active substances, wetter, tackifier, dispersant or emulsifier and, if appropriate, solvent or oil, and such concentrates are suitable for dilution with water.
The active substances concentrations in the ready-to-use preparations can be var- ied within relatively wide ranges. In general, they are from 0.0001 to 10%, preferably from 0.001 to 1 % by weight of active substances.
The active substances may also be used successfully in the ultra-low-volume process (ULV), it being possible to apply compositions comprising over 95% by weight of active substances, or even to apply the active substances without additives.
When employed in plant protection, the amounts of active substances applied are, depending on the kind of effect desired, from 0.001 to 2 kg per ha, preferably from 0.005 to 2 kg per ha, more preferably from 0.05 to 0.9 kg per ha, in particular from 0.1 to 0.75 kg per ha.
In treatment of plant propagation materials such as seeds, e. g. by dusting, coating or drenching seed, amounts of active substances of from 0.1 to 1000 g, preferably from 1 to 1000 g, more preferably from 1 to 100 g and most preferably from 5 to 100 g, per 100 kilogram of plant propagation material (preferably seed) are generally required.
When used in the protection of materials or stored products, the amount of active substances applied depends on the kind of application area and on the desired effect. Amounts customarily applied in the protection of materials are, e. g., 0.001 g to 2 kg, preferably 0.005 g to 1 kg, of active substances per cubic meter of treated material.
Various types of oils, wetters an/or adjuvants may be added to the active sub- stances or the compositions comprising them, if appropriate not until immediately prior to use (tank mix). These agents can be admixed with the compositions according to the invention in a weight ratio of 1 :100 to 100:1 , preferably 1 :10 to 10:1.
Adjuvants which can be used are in particular organic modified polysiloxanes such as Break Thru S 240®; alcohol alkoxylates such as Atplus 245®, Atplus MBA 1303®, Plurafac LF 300® and Lutensol ON 30®; EO/PO block polymers, e. g. Pluronic RPE 2035® and Genapol B®; alcohol ethoxylates such as Lutensol XP 80®; and dioctyl sul- fosuccinate sodium such as Leophen RA®.
In the compositions according to the invention the weight ratio of component (1 ) and component (2) generally depends from the properties of the active substances used, usually it is in the range of from 1 :500 to 500:1 , more particularly from 1 :100 to 100:1 , regularly in the range of from 1 :50 to 50:1 , preferably in the range of from 1 :20 to 20:1 , more preferably in the range of from 1 :10 to 10:1 and in particular in the range of from 1 :3 to 3:1 .
The components can be used individually or already partially or completely mixed with one another to prepare the composition according to the invention. It is also possible for them to be packaged and used further as combination composition such as a kit of parts.
In one embodiment of the invention, the kits may include one or more, including all, components that may be used to prepare a subject agrochemical composition. E. g., kits may include one or two of the active substances and/or an adjuvant component. One or more of the components may already be combined together or pre-formulated. In those embodiments where more than two components are provided in a kit, the components may already be combined together and as such are packaged in a single container such as a vial, bottle, can, pouch, bag or canister. In other embodiments, two or more components of a kit may be packaged separately, i. e., not pre-formulated. As such, kits may include one or more separate containers such as vials, cans, bottles, pouches, bags or canisters, each container containing a separate component for an agrochemical composition. In both forms, a component of the kit may be applied sepa- rately from or together with the further components or as a component of a combination composition according to the invention for preparing the composition according to the invention.
The user applies the composition according to the invention usually from a predos- age device, a knapsack sprayer, a spray tank or a spray plane. Here, the agrochemical composition is made up with water and/or buffer to the desired application concentration, it being possible, if appropriate, to add further auxiliaries, and the ready-to-use spray liquor or the agrochemical composition according to the invention is thus obtained. Usually, 50 to 500 liters of the ready-to-use spray liquor are applied per hectare of agricultural useful area, preferably 100 to 400 liters.
According to one embodiment, individual components of the composition according to the invention such as parts of a kit or parts of a binary mixture may be mixed by the user himself in a spray tank and further auxiliaries may be added, if appropriate (tank mix).
In a further embodiment, either individual components of the composition according to the invention or partially premixed components, e. g. components comprising component (1 ) and/or component (2), may be mixed by the user in a spray tank and further auxiliaries and additives may be added, if appropriate (tank mix). In a further embodiment, either individual components of the composition according to the invention or partially premixed components, e. g. components comprising (1 ) and/or component (2) can be applied jointly (e. .g. after tankmix) or consecutively.
It has been found that the inventive compositions exhibit also advantgeous action against animal pests from the following orders:
insects from the order of the lepidopterans (Lepidoptera), for example Agrotis ypsi- Ion, Agrotis segetum, Alabama argillacea, Anticarsia gemmatalis, Argyresthia con- jugella, Autographa gamma, Bupalus piniarius, Cacoecia murinana, Capua reticulana, Cheimatobia brumata, Chonstoneura fumiferana, Choristoneura occidentalis, Cirphis unipuncta, Cydia pomonella, Dendrolimus pini, Diaphania nitidalis, Diatraea grandi- osella, Earias insulana, Elasmopalpus lignosellus, Eupoecilia ambiguella, Evetria bou- liana, Feltia subterranea, Galleria mellonella, Grapholitha funebrana, Grapholitha mo- lesta, Heliothis armigera, Heliothis virescens, Heliothis zea, Hellula undalis, Hibernia defoliaria, Hyphantria cunea, Hyponomeuta malinellus, Keiferia lycopersicella, Lamb- dina fiscellaria, Laphygma exigua, Leucoptera coffeella, Leucoptera scitella, Lithocol- letis blancardella, Lobesia botrana, Loxostege sticticalis, Lymantria dispar, Lymantria monacha, Lyonetia clerkella, Malacosoma neustria, Mamestra brassicae, Orgyia pseu- dotsugata, Ostrinia nubilalis, Panolis flammea, Pectinophora gossypiella, Peridroma saucia, Phalera bucephala, Phthorimaea operculella, Phyllocnistis citrella, Pieris brassicae, Plathypena scabra, Plutella xylostella, Pseudoplusia includens, Rhyacionia frus- trana, Scrobipalpula absoluta, Sitotroga cerealella, Sparganothis pilleriana, Spodoptera frugiperda, Spodoptera littoralis, Spodoptera litura, Thaumatopoea pityocampa, Tortrix viridana, Trichoplusia ni and Zeiraphera canadensis,
beetles (Coleoptera), for example Agrilus sinuatus, Agriotes lineatus, Agriotes ob- scurus, Amphimallus solstitialis, Anisandrus dispar, Anthonomus grandis, Anthonomus pomorum, Aphthona euphoridae, Athous haemorrhoidalis, Atomaria linearis, Blasto- phagus piniperda, Blitophaga undata, Bruchus rufimanus, Bruchus pisorum, Bruchus lentis, Byctiscus betulae, Cassida nebulosa, Cerotoma trifurcata, Cetonia aurata, Ceuthorrhynchus assimilis, Ceuthorrhynchus napi, Chaetocnema tibialis, Conoderus vespertinus, Crioceris asparagi, Ctenicera ssp., Diabrotica longicornis, Diabrotica semipunctata, Diabrotica 12-punctata Diabrotica speciosa, Diabrotica virgifera, Epila- chna varivestis, Epitrix hirtipennis, Eutinobothrus brasiliensis, Hylobius abietis, Hypera brunneipennis, Hypera postica, Ips typographus, Lema bilineata, Lema melanopus, Leptinotarsa decemlineata, Limonius californicus, Lissorhoptrus oryzophilus, Melanotus communis, Meligethes aeneus, Melolontha hippocastani, Melolontha melolontha, Oulema oryzae, Otiorrhynchus sulcatus, Otiorrhynchus ovatus, Phaedon cochleariae, Phyllobius pyri, Phyllotreta chrysocephala, Phyllophaga sp., Phyllopertha horticola, Phyllotreta nemorum, Phyllotreta striolata, Popillia japonica, Sitona lineatus and Sito- philus granaria,
flies, mosquitoes (Diptera), e.g. Aedes aegypti, Aedes albopictus, Aedes vexans, Anastrepha ludens, Anopheles maculipennis, Anopheles crucians, Anopheles albi- manus, Anopheles gambiae, Anopheles freeborni, Anopheles leucosphyrus, Anopheles minimus, Anopheles quadrimaculatus, Calliphora vicina, Ceratitis capitata, Chrysomya bezziana, Chrysomya hominivorax, Chrysomya macellaria, Chrysops discalis, Chrysops silacea, Chrysops atlanticus, Cochliomyia hominivorax, Contarinia sorghicola Cordylobia anthropophaga, Culicoides furens, Culex pipiens, Culex nigripalpus, Culex quinquefasciatus, Culex tarsalis, Culiseta inornata, Culiseta melanura, Dacus cucurbi- tae, Dacus oleae, Dasineura brassicae, Delia antique, Delia coarctata, Delia platura, Delia radicum, Dermatobia hominis, Fannia canicularis, Geomyza Tripunctata, Gaster- ophilus intestinalis, Glossina morsitans, Glossina palpalis, Glossina fuscipes, Glossina tachinoides, Haematobia irritans, Haplodiplosis equestris, Hippelates spp., Hylemyia platura, Hypoderma lineata, Leptoconops torrens, Liriomyza sativae, Liriomyza trifolii, Lucilia caprina, Lucilia cuprina, Lucilia sericata, Lycoria pectoralis, Mansonia titillanus, Mayetiola destructor, Musca autumnalis, Musca domestica, Muscina stabulans, Oes- trus ovis, Opomyza florum, Oscinella frit, Pegomya hysocyami, Phorbia antiqua, Phor- bia brassicae, Phorbia coarctata, Phlebotomus argentipes, Psorophora columbiae, Psila rosae, Psorophora discolor, Prosimulium mixtum, Rhagoletis cerasi, Rhagoletis pomonella, Sarcophaga haemorrhoidalis, Sarcophaga spp., Simulium vittatum, Sto- moxys calcitrans, Tabanus bovinus, Tabanus atratus, Tabanus lineola, and Tabanus similis, Tipula oleracea, and Tipula paludosa
thrips (Thysanoptera), e.g. Dichromothrips corbetti, Dichromothrips ssp., Frank- liniella fusca, Frankliniella occidentalis, Frankliniella tritici, Scirtothrips citri, Thrips oryzae, Thrips palmi and Thrips tabaci, termites (Isoptera), e.g. Calotermes flavicollis, Leucotermes flavipes, Heterotermes aureus, Reticulitermes flavipes, Reticulitermes virginicus, Reticulitermes lucifugus, Reticulitermes santonensis, Reticulitermes grassei, Termes natalensis, and Coptotermes formosanus, cockroaches (Blattaria - Blattodea), e.g. Blattella germanica, Blattella asahinae, Pe- riplaneta americana, Periplaneta japonica, Periplaneta brunnea, Periplaneta fuliggi- nosa, Periplaneta australasiae, and Blatta orientalis,
bugs, aphids, leafhoppers, whiteflies, scale insects, cicadas (Hemiptera), e.g. Acrosternum hilare, Blissus leucopterus, Cyrtopeltis notatus, Dysdercus cingulatus, Dysdercus intermedius, Eurygaster integriceps, Euschistus impictiventris, Leptoglossus phyllopus, Lygus lineolaris, Lygus pratensis, Nezara viridula, Piesma quadrata, Solubea insularis , Thyanta perditor, Acyrthosiphon onobrychis, Adelges laricis, Aphidula nasturtii, Aphis fabae, Aphis forbesi, Aphis pomi, Aphis gossypii, Aphis gros- sulariae, Aphis schneideri, Aphis spiraecola, Aphis sambuci, Acyrthosiphon pisum, Aulacorthum solani , Bemisia argentifolii, Brachycaudus cardui , Brachycaudus helichrysi, Brachycaudus persicae, Brachycaudus prunicola, Brevicoryne brassicae, Capitophorus horni, Cerosipha gossypii, Chaetosiphon fragaefolii, Cryptomyzus ribis, Dreyfusia nordmannianae, Dreyfusia piceae, Dysaphis radicola, Dysaulacorthum pseudosolani, Dysaphis plantaginea, Dysaphis pyri, Empoasca fabae, Hyalopterus pruni, Hyperomyzus lactucae, Macrosiphum avenae, Macrosiphum euphorbiae, Mac- rosiphon rosae, Megoura viciae, Melanaphis pyrarius, Metopolophium dirhodum, Myzus persicae, Myzus ascalonicus, Myzus cerasi, Myzus varians, Nasonovia ribis- nigri, Nilaparvata lugens, Pemphigus bursarius, Perkinsiella saccharicida, Phorodon humuli, Psylla mali, Psylla piri, Rhopalomyzus ascalonicus, Rhopalosiphum maidis, Rhopalosiphum padi, Rhopalosiphum insertum, Sappaphis mala, Sappaphis mali, Schizaphis graminum, Schizoneura lanuginosa, Sitobion avenae, Trialeurodes vapo- rariorum, Toxoptera aurantiiand, Viteus vitifolii, Cimex lectularius, Cimex hemipterus, Reduvius senilis, Triatoma spp., and Arilus critatus.
ants, bees, wasps, sawflies (Hymenoptera), e.g. Athalia rosae, Atta cephalotes, Atta capiguara, Atta cephalotes, Atta laevigata, Atta robusta, Atta sexdens, Atta texana, Crematogaster spp., Hoplocampa minuta, Hoplocampa testudinea, Lasius niger, Monomorium pharaonis, Solenopsis geminata, Solenopsis invicta, Solenopsis richteri, Solenopsis xyloni, Pogonomyrmex barbatus, Pogonomyrmex californicus, Pheidole megacephala, Dasym uti l la occidental is , Bom bus spp. , Vespu la sq uamosa , Pa ravespula vulgaris , Paravespu la pen nsylvanica , Pa ravespula germanica, Dolichovespula maculata, Vespa crabro, Polistes rubiginosa, Camponotus floridanus, and Linepithema humile,
crickets, grasshoppers, locusts (Orthoptera), e.g. Acheta domestica, Gryllotalpa gryllotalpa, Locusta migratoria, Melanoplus bivittatus, Melanoplus femurrubrum, Melanoplus mexicanus, Melanoplus sanguinipes, Melanoplus spretus, Nomadacris septemfasciata, Schistocerca americana, Schistocerca gregaria, Dociostaurus maroc- canus, Tachycines asynamorus, Oedaleus senegalensis, Zonozerus variegatus, Hiero- glyphus daganensis, Kraussaria angulifera, Calliptamus italicus, Chortoicetes terminif- era, and Locustana pardalina,
Arachnoidea, such as arachnids (Acarina), e.g. of the families Argasidae, Ixodidae and Sarcoptidae, such as Amblyomma americanum, Amblyomma variegatum, Ambry- omma maculatum, Argas persicus, Boophilus annulatus, Boophilus decoloratus, Boophilus microplus, Dermacentor silvarum, Dermacentor andersoni, Dermacentor variabilis, Hyalomma truncatum, Ixodes ricinus, Ixodes rubicundus, Ixodes scapularis, Ixodes holocyclus, Ixodes pacificus, Ornithodorus moubata, Ornithodorus hermsi, Orni- thodorus turicata, Ornithonyssus bacoti, Otobius megnini, Dermanyssus gallinae, Pso- roptes ovis, Rhipicephalus sanguineus, Rhipicephalus appendiculatus, Rhipicephalus evertsi, Sarcoptes scabiei, and Eriophyidae spp. such as Aculus schlechtendali, Phyl- locoptrata oleivora and Eriophyes sheldoni; Tarsonemidae spp. such as Phytonemus pallidus and Polyphagotarsonemus latus; Tenuipalpidae spp. such as Brevipalpus phoenicis; Tetranychidae spp. such as Tetranychus cinnabarinus, Tetranychus kan- zawai, Tetranychus pacificus, Tetranychus telarius and Tetranychus urticae, Panony- chus ulmi, Panonychus citri, and Oligonychus pratensis; Araneida, e.g. Latrodectus mactans, and Loxosceles reclusa,
fleas (Siphonaptera), e.g. Ctenocephalides felis, Ctenocephalides canis, Xenopsylla cheopis, Pulex irritans, Tunga penetrans, and Nosopsyllus fasciatus,
silverfish, firebrat (Thysanura), e.g. Lepisma saccharina and Thermobia domestica, centipedes (Chilopoda), e.g. Scutigera coleoptrata,
millipedes (Diplopoda), e.g. Narceus spp.,
Earwigs (Dermaptera), e.g. forficula auricularia,
lice (Phthiraptera), e.g. Pediculus humanus capitis, Pediculus humanus corporis, Pthirus pubis, Haematopinus eurysternus, Haematopinus suis, Linognathus vituli, Bovi- cola bovis, Menopon gallinae, Menacanthus stramineus and Solenopotes capillatus.
The compositions according to the invention can be applied to any and all developmental stages of pests, such as egg, larva, pupa, and adult. The pests may be controlled by contacting the target pest, its food supply, habitat, breeding ground or its lo- cus with a pesticidally effective amount of the inventive compositions or pesticidal compositions.
"Locus" means a plant, plant propagation material (preferably seed), soil, area, material or environment in which a pest is growing or may grow.
In general, "pesticidally effective amount" means the amount of the inventive com- positions or of pesticidal compositions needed to achieve an observable effect on growth, including the effects of necrosis, death, retardation, prevention, and removal, destruction, or otherwise diminishing the occurrence and activity of the target organism. The pesticidally effective amount can vary for the various inventive compositions. A pesticidally effective amount of the compositions will also vary according to the prevail- ing conditions such as desired pesticidal effect and duration, weather, target species, locus, mode of application, and the like.
As said above, the present invention also relates to a method for improving the health of plants, wherein the plant, the locus where the plant is growing or is expected to grow or plant propagation material, from which the plant grows, is treated with an plant health effective amount of an inventive mixture.
The term "plant effective amount" denotes an amount of the inventive mixtures, which is sufficient for achieving plant health effects as defined hereinbelow. More exemplary information about amounts, ways of application and suitable ratios to be used is given herein. Anyway, the skilled artisan is well aware of the fact that such an amount can vary in a broad range and is dependent on various factors, e.g. the treated cultivated plant or material and the climatic conditions.
The inventive compositions are employed by treating the fungi or the plants, plant propagation materials (preferably seeds), materials or soil to be protected from fungal attack with a pesticidally effective amount of the active compounds. The application can be carried out both before and after the infection of the materials, plants or plant propagation materials (preferably seeds) by the pests.
In the method of combating phytopathogenic fungi the application rates of the mix- tures according to the invention are usually from 0,3 g/ha to 2000 g/ha, preferably 5 g/ha to 2000 g/ha, more preferably from 50 to 900 g/ha, in particular from 50 to 750 g/ha.
In the method of combating animal pests (insects, acarids or nematodes) the application rates of the compositions according to the invention are usually from 0,3 g/ha to 2000 g/ha, preferably 5 g/ha to 2000 g/ha, more preferably from 50 to 900 g/ha, in particular from 50 to 750 g/ha.
The inventive compositions can also be employed for protecting plants from attack or infestation by animal pests (insects, acarids or nematodes) comprising contacting a plant, or soil or water in which the plant is growing.
In the context of the present invention, the term plant refers to an entire plant, a part of the plant or the propagation material of the plant.
The inventive compositions are effective through both contact (via soil, glass, wall, bed net, carpet, plant parts or animal parts), and ingestion (bait, or plant part) and through trophallaxis and transfer.
Preferred application methods are into water bodies, via soil, cracks and crevices, pastures, manure piles, sewers, into water, on floor, wall, or by perimeter spray application and bait.
According to another preferred embodiment of the invention, for use against non crop pests such as ants, termites, wasps, flies, mosquitoes, crickets, locusts, or cock- roaches the inventive mixtures are prepared into a bait preparation.
The bait can be a liquid, a solid or a semisolid preparation (e.g. a gel). The bait employed in the composition is a product which is sufficiently attractive to incite insects such as ants, termites, wasps, flies, mosquitoes, crickets etc. or cockroaches to eat it. This attractant may be chosen from feeding stimulants or para and / or sex phero- mones readily known in the art.
Methods to control infectious diseases transmitted by insects (e.g. malaria, dengue and yellow fever, lymphatic filariasis, and leishmaniasis) with the inventive mixtures and their respective compositions also comprise treating surfaces of huts and houses, air spraying and impregnation of curtains, tents, clothing items, bed nets, tsetse-fly trap or the like. Insecticidal compositions for application to fibers, fabric, knitgoods, non- wovens, netting material or foils and tarpaulins preferably comprise a composition including the inventive mixtures, optionally a repellent and at least one binder. The inventive compositions can be used for protecting wooden materials such as trees, board fences, sleepers, etc. and buildings such as houses, outhouses, factories, but also construction materials, furniture, leathers, fibers, vinyl articles, electric wires and cables etc. from ants and/or termites, and for controlling ants and termites from doing harm to crops or human being (e.g. when the pests invade into houses and public facilities).
In the case of soil treatment or of application to the pests dwelling place or nest, the quantity of active ingredient ranges from 0.0001 to 500 g per 100 m2, preferably from 0.001 to 20 g per 100 m2.
Customary application rates in the protection of materials are, for example, from
0.01 g to 1000 g of active compound per m2 treated material, desirably from 0.1 g to 50 g per m2.
Insecticidal compositions for use in the impregnation of materials typically contain from 0.001 to 95 weight %, preferably from 0.1 to 45 weight %, and more preferably from 1 to 25 weight % of at least one repellent and / or insecticide.
For use in bait compositions, the typical content of active ingredient is from 0.0001 weight % to 15 weight %, desirably from 0.001 weight % to 5% weight % of active compound. The composition used may also comprise other additives such as a solvent of the active material, a flavoring agent, a preserving agent, a dye or a bitter agent. Its attractiveness may also be enhanced by a special color, shape or texture.
For use in spray compositions, the content of the mixture of the active ingredients is from 0.001 to 80 weights %, preferably from 0.01 to 50 weight % and most preferably from 0.01 to 15 weight %.

Claims

claim:
A composition comprising the following components (1 ) and (2):
(1 ) a fungicidal compound (I) selected from inhibitors of phospholipid biosynthesis and cell wall deposition; and
(2) an insecticidal compound (II) selected from the groups (A) to (F):
(A) acetylcholinesterase inhibitors, selected from carbamates, organo- phospates and triazamate;
(B) sodium channel modulators;
(C) insect growth regulators;
(D) macrocyclic lactone insecticides;
(E) respiration inhibitors, selected from mitochondrial complex I inhibitors and mitochondrial complex II inhibitors; and
(F) insecticides, selected from chlorfenapyr, fenbutatin oxide, indoxacarb, metaflumizone, pymetrozine, cyhexatin, diafenthiuron, propargite, benclothiaz, bifenazate, cartap, flonicamid, pyridalyl, thiocyclam, cye- nopyrafen, dicofol, flupyrazofos, cyflumetofen, amidoflumet, imicya- fos, bistrifluron and pyrifluquinazon; in a synergistically effective amount.
The composition as claimed in claim 1 , wherein component (1 ) is selected from benthiavalicarb, dimethomorph, flumorph, iprovalicarb, mandipropamid, pyri- morph, valifenalate, N-(1 -(1 -(4-cyanophenyl)ethanesulfonyl)-but-2-yl) carbamic acid-(4-fluorophenyl) ester and 1-(4-chloro-phenyl)-1 -(propin-2-yl-oxy)-3-(4-(3,4- dimethoxy-phenyl)-isoxazol-5-yl)-propan-2-one.
3. The composition as claimed in 1 , wherein component (1 ) is selected from benthiavalicarb, dimethomorph, flumorph, iprovalicarb, mandipropamid, pyrimorph and 1 -(4-chloro-phenyl)-1 -(propin-2-yl-oxy)-3-(4-(3,4-dimethoxy-phenyl)-isoxazol- 5-yl)-propan-2-one.
4. The composition as claimed in claim 1 , wherein component (1 ) is selected from dimethomorph, flumorph, iprovalicarb, mandipropamid and 1 -(4-chloro-phenyl)-1 - (propin-2-yl-oxy)-3-(4-(3,4-dimethoxy-phenyl)-isoxazol-5-yl)-propan-2-one. 5. The composition as claimed in claim 1 , wherein component (1 ) is dimethomorph.
6. The composition as claimed in any one of claims 1 or 5, wherein component (2) is selected from groups (A) to (F), wherein (A) are carbamates, selected from alanycarb, aldicarb, bendiocarb, benfura- carb, carbaryl, carbofuran, carbosulfan, ethiofencarb, fenoxycarb, furathio- carb, methiocarb, methomyl, oxamyl, pirimicarb, propoxur, thiodicarb; or- ganophospates, selected from acephate, azamethiphos, azinphos-methyl, cadusafos, chlorfenvinphos, chlorpyrifos, dimethoate, diazinon, dichlorvos, dicrotophos disulfoton, ethion, fenitrothion, fenthion, isoxathion, malathion, methamidophos, methidathion, methyl-parathion, mevinphos, monocroto- phos, oxydemeton-methyl, parathion, phenthoate, phosalone, phorate, phosmet, phosphamidon, phoxim, pirimiphos-methyl, profenofos, prothio- fos, tebupirimfos, terbufos, tetrachlorvinphos, triazophos, trichlorfon; and triazamate;
(B) are sodium channel modulators, selected from betacyfluthrin, bifenthrin, cypermethrin, alpha-cypermethrin, zeta-cypermethrin, deltamethrin, esfen- valerate, etofenprox, lambda-cyhalothrin, permethrin, tefluthrin, cyfluthrin, acrinathrin, allethrin, cycloprothrin, cyhalothrin, cyphenothrin, beta- cypermethrin, fenpropathrin, fenvalerate, flucythrinate, imiprothrin, pral- lethrin, pyrethrin I and II, resmethrin, silafluofen, tau-fluvalinate, tetrame- thrin, tralomethrin, transfluthrin, profluthrin, dimefluthrin, gamma- cyhalothrin, theta-cypermethrin;
(C) are insect growth regulators, selected from flufenoxuron, lufenuron, novalu- ron, buprofezin, teflubenzuron, methoxyfenozide, chlorfluazuron, cyrama- zin, diflubenzuron, flucycloxuron, hexaflumuron, triflumuron; diofenolan, he- xythiazox, etoxazole, clofentezine, halofenozide, tebufenozide, azadirach- tin, pyriproxyfen, methoprene, spirodiclofen, spiromesifen, spirotetramat; are macrocyclic lactone insecticides, selected from abamectin, emamectin, milbemectin, lepimectin, spinetoram, spinosad;
(E) are mitochondrial complex I inhibitors, selected from fenazaquin, pyridaben, tolfenpyrad, flufenerim, tebufenpyrad; and mitochondrial complex II inhibitors, selected from acequinocyl, fluacyprim, hydramethylnon, 2,2-Dimethyl- propionic acid (Z)-2-cyano-1 -(2-methyl-4-trifluoromethyl-thiazol-5-yl)-2-(2- phenyl-thiazol-4-yl)-vinyl ester; and
(F) are insecticides, selected from chlorfenapyr, fenbutatin oxide, indoxacarb, metaflumizone, pymetrozine, cyhexatin, diafenthiuron, propargite, ben- clothiaz, bifenazate, cartap, flonicamid, pyridalyl, thiocyclam, cyenopyrafen, dicofol, flupyrazofos, cyflumetofen, amidoflumet, imicyafos, bistrifluron, py- rifluquinazon.
The composition as claimed in any one of claims 1 to 6, wherein component (2) is selected from aldicarb, carbofuran, carbosulfan, methiocarb, thiodicarb, dimetho- ate, bifenthrin, cypermethrin, zeta-cypermethrin, deltamethrin, esfen-valerate, etofenprox, lambda-cyhalothrin, permethrin, cyfluthrin, flufenoxuron, methoxy- fenozide, emamectin, hydramethylnon, chlorfenapyr, fenbutatin oxide, indoxacarb, and pymetrozine.
The composition as claimed in any one of claims 1 to 6, wherein component (2) is selected from methiocarb, thiodicarb, bifenthrin, deltamethrin, lambda- cyhalothrin, chlorfenapyr and pymetrozine.
The composition as claimed in any one of claims 1 to 8, comprising component (1 ) and component (2) in a total weight ratio of from 500:1 to 1 :500.
A plant propagation material, comprising the composition as defined in any one claims 1 to 9 in an amount of from 0.01 g to 10 kg per 100 kg of plant propagation material.
A method for controlling pests, which method comprises treating the pest, their habitat, breeding grounds, their locus or the plants to be protected against pest attack, the soil or plant propagation material, with a composition comprising component (1 ) and component (2) in a synergistically effective amount, as defined in any one of claims 1 to 9.
The method as claimed in claim 11 , wherein component (1 ) and component (2) are applied simultaneously, that is jointly or separately, or in succession.
13. An agrochemical composition, comprising a liquid or solid carrier and a composition as defined in any one of claims 1 to 9.
PCT/IB2011/052537 2010-06-14 2011-06-10 Pesticidal compositions WO2011158158A1 (en)

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